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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:epoxycarotenoid
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Accession:CHEBI:23043 term browser browse the term
Synonyms:related_synonym: carotenoid epoxides;   epoxycarotenoids


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9'-cis-neoxanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIFM1 apoptosis inducing factor mitochondria associated 1 affects localization EXP neoxanthin affects the localization of AIFM1 protein CTD PMID:17186379 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879
Ensembl chr  X:130,124,666...130,165,879
JBrowse link
G CASP3 caspase 3 multiple interactions EXP neoxanthin results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:17186379 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP8 caspase 8 increases activity EXP neoxanthin results in increased activity of CASP8 protein CTD PMID:17186379 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,287,711
JBrowse link
G CASP9 caspase 9 multiple interactions EXP neoxanthin results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:17186379 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
all-trans-neoxanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIFM1 apoptosis inducing factor mitochondria associated 1 affects localization EXP neoxanthin affects the localization of AIFM1 protein CTD PMID:17186379 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879
Ensembl chr  X:130,124,666...130,165,879
JBrowse link
G CASP3 caspase 3 multiple interactions EXP neoxanthin results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:17186379 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP8 caspase 8 increases activity EXP neoxanthin results in increased activity of CASP8 protein CTD PMID:17186379 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,287,711
JBrowse link
G CASP9 caspase 9 multiple interactions EXP neoxanthin results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:17186379 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
fucoxanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOX1 acyl-CoA oxidase 1 increases expression ISO fucoxanthin results in increased expression of ACOX1 mRNA CTD PMID:20519145 NCBI chr17:75,941,507...75,979,199
Ensembl chr17:75,941,507...75,979,177
JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions ISO fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of AKT1 protein] CTD PMID:26418808 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions
decreases expression
EXP Acetylcysteine inhibits the reaction [fucoxanthin results in decreased expression of BCL2L1 protein] CTD PMID:20594983 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G CASP3 caspase 3 increases cleavage
multiple interactions
EXP fucoxanthin results in increased cleavage of CASP3 protein
Acetylcysteine inhibits the reaction [fucoxanthin results in increased cleavage of CASP3 protein]
CTD PMID:20594983 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP7 caspase 7 multiple interactions
increases cleavage
EXP Acetylcysteine inhibits the reaction [fucoxanthin results in increased cleavage of CASP7 protein] CTD PMID:20594983 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
JBrowse link
G CAT catalase multiple interactions ISO fucoxanthin inhibits the reaction [Carrageenan results in decreased activity of CAT protein] CTD PMID:26418808 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G DRD3 dopamine receptor D3 increases activity EXP fucoxanthin results in increased activity of DRD3 protein CTD PMID:31323226 NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
JBrowse link
G DRD4 dopamine receptor D4 increases activity EXP fucoxanthin results in increased activity of DRD4 protein CTD PMID:31323226 NCBI chr11:637,269...640,706
Ensembl chr11:637,269...640,706
JBrowse link
G FLG filaggrin decreases expression ISO fucoxanthin results in decreased expression of FLG mRNA CTD PMID:27590588 NCBI chr 1:152,302,165...152,325,239
Ensembl chr 1:152,302,165...152,325,239
Ensembl chr 1:152,302,165...152,325,239
JBrowse link
G GJA1 gap junction protein alpha 1 increases expression EXP fucoxanthin results in increased expression of GJA1 mRNA; fucoxanthin results in increased expression of GJA1 protein CTD PMID:19737546 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G GJB1 gap junction protein beta 1 increases expression EXP fucoxanthin results in increased expression of GJB1 mRNA; fucoxanthin results in increased expression of GJB1 protein CTD PMID:19737546 NCBI chr  X:71,215,239...71,225,516
Ensembl chr  X:71,212,811...71,225,516
Ensembl chr  X:71,212,811...71,225,516
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase decreases activity ISO fucoxanthin results in decreased activity of HMGCR protein CTD PMID:20519145 NCBI chr 5:75,336,334...75,362,116
Ensembl chr 5:75,336,329...75,362,101
JBrowse link
G HMOX1 heme oxygenase 1 increases expression ISO
EXP
fucoxanthin results in increased expression of HMOX1 protein CTD PMID:23358145 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,207
JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] CTD PMID:22735499 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL6 interleukin 6 multiple interactions ISO fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] CTD PMID:22735499 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G MAOA monoamine oxidase A decreases activity EXP fucoxanthin results in decreased activity of MAOA protein CTD PMID:31323226 NCBI chr  X:43,655,006...43,746,817
Ensembl chr  X:43,654,907...43,746,824
JBrowse link
G MAOB monoamine oxidase B decreases activity EXP fucoxanthin results in decreased activity of MAOB protein CTD PMID:31323226 NCBI chr  X:43,766,610...43,882,450
Ensembl chr  X:43,766,610...43,882,450
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of MAPK1 protein] CTD PMID:26418808 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,754,500...21,867,680
Ensembl chr22:21,754,500...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of MAPK3 protein] CTD PMID:26418808 NCBI chr16:30,114,105...30,123,309
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; fucoxanthin inhibits the reaction [Carrageenan results in increased expression of NOS2 protein] CTD PMID:22735499, PMID:26418808 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha increases expression ISO fucoxanthin results in increased expression of PPARA mRNA CTD PMID:20519145 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,756
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma decreases expression ISO fucoxanthin results in decreased expression of PPARG mRNA CTD PMID:20519145 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO fucoxanthin analog affects the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; fucoxanthin analog affects the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; fucoxanthin inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein] CTD PMID:22735499, PMID:26418808 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,423
JBrowse link
G RETN resistin decreases expression ISO fucoxanthin results in decreased expression of RETN protein CTD PMID:20519145 NCBI chr19:7,669,049...7,670,455
Ensembl chr19:7,669,049...7,670,455
JBrowse link
G TNF tumor necrosis factor multiple interactions ISO fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:22735499 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 24216
    chemical entity 24181
      molecular entity 24130
        main group molecular entity 23996
          gas molecular entity 19334
            oxirane 5823
              epoxide 5821
                epoxycarotenoid 28
                  9-cis-epoxycarotenoid + 4
                  beta-carotene 15,15'-epoxide 0
                  beta-carotene 5,6-epoxide + 0
                  epoxycarotenol + 28
Path 2
Term Annotations click to browse term
  CHEBI ontology 24216
    subatomic particle 24167
      composite particle 24167
        hadron 24167
          baryon 24167
            nucleon 24167
              atomic nucleus 24167
                atom 24167
                  main group element atom 23996
                    main group molecular entity 23996
                      s-block molecular entity 23130
                        hydrogen molecular entity 22938
                          hydrides 21046
                            organic hydride 20077
                              organic fundamental parent 20077
                                hydrocarbon 19444
                                  terpene 9980
                                    tetraterpene 419
                                      carotene 419
                                        carotenoid 419
                                          xanthophyll 153
                                            epoxycarotenoid 28
                                              9-cis-epoxycarotenoid + 4
                                              beta-carotene 15,15'-epoxide 0
                                              beta-carotene 5,6-epoxide + 0
                                              epoxycarotenol + 28
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.