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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Solithromycin
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Accession:CHEBI:230261 term browser browse the term
Synonyms:exact_synonym: (1S,2R,5S,7R,8R,9R,11R,13R,14R)-15-[4-[4-(3-aminophenyl)triazol-1-yl]butyl]-8-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-5-luoro-9-methoxy-1,5,7,9,11,13-hexamethyl-3,17-dioxa-15-azabicyclo[12.3.0]heptadecane-4,6,12,16-tetrone
 related_synonym: Formula=C43H65FN6O10;   InChI=1S/C43H65FN6O10/c1-12-32-43(8)35(50(40(55)60-43)19-14-13-18-49-23-30(46-47-49)28-16-15-17-29(45)21-28)26(4)33(51)24(2)22-41(6,56-11)37(27(5)36(53)42(7,44)39(54)58-32)59-38-34(52)31(48(9)10)20-25(3)57-38/h15-17,21,23-27,31-32,34-35,37-38,52H,12-14,18-20,22,45H2,1-11H3/t24-,25-,26+,27+,31+,32-,34-,35-,37-,38+,41-,42+,43-/m1/s1;   InChIKey=IXXFZUPTQVDPPK-ZAWHAJPISA-N;   SMILES=F[C@]1(C(=O)[C@@H]([C@@H](O[C@@H]2O[C@@H](C[C@H](N(C)C)[C@H]2O)C)[C@](OC)(C[C@H](C(=O)[C@@H]([C@H]3N(C(O[C@@]3([C@H](OC1=O)CC)C)=O)CCCCN4N=NC(=C4)C5=CC(N)=CC=C5)C)C)C)C)C
 xref: Chemspider:25056854;   DrugBank:DB09308
 xref_mesh: MESH:C547755
 xref: PDBeChem:EM1


show annotations for term's descendants           Sort by:
Solithromycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO solithromycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]
solithromycin inhibits the reaction [Tobacco Smoke Pollution results in increased expression of MMP9 protein]		 CTD PMID:23359665 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO solithromycin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:23359665 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    chemical entity 19909
      atom 19909
        nonmetal atom 19832
          oxygen atom 19570
            oxygen molecular entity 19570
              organooxygen compound 19193
                carbohydrates and carbohydrate derivatives 15275
                  carbohydrate derivative 14313
                    aminoglycoside 11271
                      Solithromycin 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    p-block element atom 19849
                      carbon group element atom 19766
                        carbon atom 19785
                          organic molecular entity 19785
                            heteroorganic entity 19541
                              organochalcogen compound 19301
                                organooxygen compound 19193
                                  carbohydrates and carbohydrate derivatives 15275
                                    carbohydrate 15302
                                      carbohydrate derivative 14313
                                        glycosyl compound 13078
                                          glycoside 11847
                                            aminoglycoside 11271
                                              Solithromycin 2
paths to the root