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G |
ABCB1 |
ATP binding cassette subfamily B member 1 |
multiple interactions |
EXP |
Calcium deficiency inhibits the reaction [ABCB1 protein results in increased export of Xanthenes]; Calcium inhibits the reaction [Magnesium results in increased activity of ABCB1 protein] |
CTD |
PMID:2900677 PMID:25862123 |
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NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
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G |
ABCB11 |
ATP binding cassette subfamily B member 11 |
multiple interactions |
EXP |
Calcium deficiency inhibits the reaction [ABCB11 protein results in increased export of Taurocholic Acid] |
CTD |
PMID:25862123 |
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NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324
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G |
ABCC2 |
ATP binding cassette subfamily C member 2 |
multiple interactions |
EXP |
Calcium deficiency inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein] |
CTD |
PMID:25862123 |
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NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
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G |
ACO2 |
aconitase 2 |
increases activity multiple interactions |
ISO |
Calcium results in increased activity of ACO2 protein [Calcium results in increased activity of ACO2 protein] which results in increased reduction of thiazolyl blue; [Nicardipine results in decreased uptake of Calcium] which results in decreased activity of ACO2 protein |
CTD |
PMID:12548706 |
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NCBI chr22:41,469,117...41,528,974
Ensembl chr22:41,447,830...41,529,273
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G |
ACTB |
actin beta |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of ACTB mRNA |
CTD |
PMID:15913539 |
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NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902
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G |
ADCY5 |
adenylate cyclase 5 |
decreases activity increases response to substance |
EXP ISO |
Calcium results in decreased activity of ADCY5 protein ADCY5 protein results in increased susceptibility to Calcium |
CTD |
PMID:12065575 PMID:12869393 |
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NCBI chr 3:123,282,296...123,449,090
Ensembl chr 3:123,282,296...123,449,090
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G |
ADCY9 |
adenylate cyclase 9 |
multiple interactions |
EXP |
Calcium inhibits the reaction [Miconazole results in increased activity of ADCY9 protein]; Tacrolimus inhibits the reaction [Calcium inhibits the reaction [Miconazole results in increased activity of ADCY9 protein]] |
CTD |
PMID:30607468 |
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NCBI chr16:3,953,387...4,116,442
Ensembl chr16:3,953,387...4,116,442
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G |
ADCYAP1 |
adenylate cyclase activating polypeptide 1 |
increases abundance affects abundance multiple interactions |
ISO |
ADCYAP1 protein results in increased abundance of Calcium ADCYAP1 protein affects the abundance of Calcium Calcium affects the reaction [ADCYAP1 protein results in increased expression of SELENOT mRNA]; SELENOT protein affects the reaction [ADCYAP1 protein results in increased abundance of Calcium] |
CTD |
PMID:18198219 PMID:21039959 |
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NCBI chr18:904,411...912,172
Ensembl chr18:904,871...912,172
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G |
ADGRL1 |
adhesion G protein-coupled receptor L1 |
multiple interactions |
ISO |
[alpha-latrotoxin binds to ADGRL1 protein] which results in increased uptake of Calcium; [black widow spider venom binds to ADGRL1 protein] which results in increased uptake of Calcium |
CTD |
PMID:10026162 |
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NCBI chr19:14,147,743...14,206,169
Ensembl chr19:14,147,743...14,206,187
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G |
ADGRL2 |
adhesion G protein-coupled receptor L2 |
multiple interactions |
ISO |
[alpha-latrotoxin binds to ADGRL2 protein] which results in increased uptake of Calcium; [black widow spider venom binds to ADGRL2 protein] which results in increased uptake of Calcium |
CTD |
PMID:10026162 |
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NCBI chr 1:81,306,132...81,993,932
Ensembl chr 1:81,306,147...81,993,932
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G |
ADM |
adrenomedullin |
decreases expression |
EXP |
Calcium results in decreased expression of ADM mRNA |
CTD |
PMID:20682585 |
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NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397
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G |
ADRA1A |
adrenoceptor alpha 1A |
multiple interactions affects transport |
ISO EXP |
[Epinephrine binds to and results in increased activity of ADRA1A protein] which results in increased transport of Calcium; [Phenylephrine binds to and results in increased activity of ADRA1A protein] which results in increased transport of Calcium; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of EIF4EBP1 protein]; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of MTOR protein]; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of RPS6KB1 protein] 5-methylurapidil inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; [A 61603 results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Epinephrine binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Oxymetazoline binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium] ADRA1A protein affects the transport of Calcium |
CTD |
PMID:12935885 PMID:15306222 PMID:15639650 PMID:15672411 PMID:16498073 PMID:20030735 More...
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NCBI chr 8:26,748,150...26,867,379
Ensembl chr 8:26,748,150...26,867,278
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G |
ADRA1B |
adrenoceptor alpha 1B |
multiple interactions |
EXP |
[Epinephrine binds to and results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; [Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; Carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; Carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium] |
CTD |
PMID:15306222 PMID:16498073 PMID:20030735 |
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NCBI chr 5:159,865,086...159,989,205
Ensembl chr 5:159,865,080...159,973,012
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G |
ADRA1D |
adrenoceptor alpha 1D |
multiple interactions |
EXP |
[Epinephrine binds to and results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; [Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium] |
CTD |
PMID:15306222 PMID:20030735 |
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NCBI chr20:4,220,630...4,249,287
Ensembl chr20:4,220,630...4,249,287
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G |
ADRA2A |
adrenoceptor alpha 2A |
multiple interactions |
EXP |
[Epinephrine binds to and results in increased activity of ADRA2A protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA2A protein] which results in increased abundance of Calcium |
CTD |
PMID:20030735 |
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NCBI chr10:111,077,029...111,080,907
Ensembl chr10:111,077,029...111,080,907
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G |
ADRA2B |
adrenoceptor alpha 2B |
multiple interactions |
EXP |
[Epinephrine binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; [Oxymetazoline binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; [xylometazoline binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium |
CTD |
PMID:20030735 |
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NCBI chr 2:96,112,876...96,116,571
Ensembl chr 2:96,112,876...96,116,571
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G |
ADRA2C |
adrenoceptor alpha 2C |
multiple interactions |
EXP |
[Epinephrine binds to and results in increased activity of ADRA2C protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA2C protein] which results in increased abundance of Calcium |
CTD |
PMID:20030735 |
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NCBI chr 4:3,766,385...3,768,526
Ensembl chr 4:3,766,348...3,768,526
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G |
ADRB2 |
adrenoceptor beta 2 |
multiple interactions |
ISO EXP |
[Terbutaline binds to and results in increased activity of ADRB2 protein] which affects the abundance of Calcium [Benzo(a)pyrene binds to ADRB2 protein] which results in increased transport of Calcium; ADRB2 protein promotes the reaction [Benzo(a)pyrene results in increased transport of Calcium] |
CTD |
PMID:10372813 PMID:22167199 |
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NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623
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G |
AGO2 |
argonaute RISC catalytic component 2 |
multiple interactions |
ISO |
Calcium affects the reaction [PICK1 protein binds to AGO2 protein]; Calcium deficiency inhibits the reaction [Excitatory Amino Acid Agonists inhibits the reaction [PICK1 protein binds to AGO2 protein]] |
CTD |
PMID:28404816 |
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NCBI chr 8:140,520,156...140,642,313
Ensembl chr 8:140,520,156...140,635,633
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G |
AGT |
angiotensinogen |
increases uptake affects localization multiple interactions increases abundance |
EXP ISO |
AGT protein results in increased uptake of Calcium AGT protein affects the localization of Calcium 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [AGT protein affects the localization of Calcium]; bafilomycin A1 inhibits the reaction [AGT protein affects the localization of Calcium]; Heparin inhibits the reaction [AGT protein affects the localization of Calcium]; Losartan inhibits the reaction [AGT protein affects the localization of Calcium]; Saralasin inhibits the reaction [AGT protein affects the localization of Calcium]; Sirolimus inhibits the reaction [AGT protein affects the localization of Calcium]; xestospongin C inhibits the reaction [AGT protein affects the localization of Calcium] [AGT protein results in increased abundance of Calcium] which results in increased abundance of Reactive Oxygen Species Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein] benidipine inhibits the reaction [AGT protein results in increased uptake of Calcium]; Mibefradil inhibits the reaction [AGT protein results in increased uptake of Calcium] |
CTD |
PMID:10660688 PMID:18331727 PMID:18854758 PMID:21613610 |
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NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
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G |
AGTR1 |
angiotensin II receptor type 1 |
affects expression |
ISO |
Calcium affects the expression of AGTR1A mRNA |
CTD |
PMID:15913539 |
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NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008
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G |
AKAP1 |
A-kinase anchoring protein 1 |
affects expression |
ISO |
Calcium affects the expression of AKAP1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr17:57,085,246...57,121,344
Ensembl chr17:57,085,092...57,121,346
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G |
AKAP11 |
A-kinase anchoring protein 11 |
affects expression |
ISO |
Calcium affects the expression of AKAP11 mRNA |
CTD |
PMID:15913539 |
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NCBI chr13:42,271,477...42,323,261
Ensembl chr13:42,272,152...42,323,261
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G |
AKT1 |
AKT serine/threonine kinase 1 |
affects abundance affects expression multiple interactions affects response to substance |
EXP ISO |
AKT1 protein affects the abundance of Calcium Calcium affects the expression of AKT1 mRNA [Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein; Calcium affects the reaction [P2RY1 protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; CAMKK2 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; PDK1 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; PX-866 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; STO 609 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; W 7 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein] AKT1 protein affects the susceptibility to Calcium |
CTD |
PMID:15913539 PMID:16094411 PMID:16236484 PMID:28634229 |
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NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
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G |
ALDH2 |
aldehyde dehydrogenase 2 family member |
multiple interactions |
ISO EXP |
ALDH2 protein inhibits the reaction [Ethanol affects the abundance of Calcium] Calcium affects the reaction [ALDH2 gene SNP affects the abundance of Lead] |
CTD |
PMID:17590987 PMID:28212632 |
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NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
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G |
ALG2 |
ALG2 alpha-1,3/1,6-mannosyltransferase |
affects binding |
EXP |
Calcium binds to ALG2 protein |
CTD |
PMID:18997320 |
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NCBI chr 9:99,216,425...99,221,942
Ensembl chr 9:99,216,425...99,221,942
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G |
ALOX5 |
arachidonate 5-lipoxygenase |
multiple interactions |
EXP |
Calcium promotes the reaction [L 708714 binds to ALOX5 protein] |
CTD |
PMID:7577949 |
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NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119
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G |
ALPP |
alkaline phosphatase, placental |
affects binding |
EXP |
Calcium binds to ALPP protein |
CTD |
PMID:16815919 |
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NCBI chr 2:232,378,751...232,382,889
Ensembl chr 2:232,378,724...232,382,889
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G |
ANO1 |
anoctamin 1 |
multiple interactions increases activity |
EXP |
9-phenanthrol inhibits the reaction [Calcium results in increased activity of ANO1 protein] |
CTD |
PMID:25573456 |
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NCBI chr11:69,965,997...70,189,530
Ensembl chr11:69,985,907...70,189,530
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G |
ANXA1 |
annexin A1 |
affects activity |
ISO |
Calcium affects the activity of ANXA1 protein |
CTD |
PMID:20655937 |
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NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393
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G |
ANXA5 |
annexin A5 |
multiple interactions |
EXP |
Calcium binds to and results in increased activity of ANXA5 protein; Calcium promotes the reaction [Phosphatidylserines binds to ANXA5 protein] |
CTD |
PMID:11578147 PMID:16076491 |
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NCBI chr 4:121,667,946...121,696,980
Ensembl chr 4:121,667,946...121,696,995
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G |
AOC1 |
amine oxidase copper containing 1 |
affects binding |
EXP |
AOC1 protein binds to Calcium |
CTD |
PMID:12072962 |
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NCBI chr 7:150,852,120...150,861,504
Ensembl chr 7:150,824,627...150,861,504
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G |
APOE |
apolipoprotein E |
affects abundance affects expression |
ISO |
APOE protein affects the abundance of Calcium Calcium affects the expression of APOE mRNA |
CTD |
PMID:15913539 PMID:17899169 |
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NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
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G |
APOM |
apolipoprotein M |
affects expression |
ISO |
Calcium affects the expression of APOM mRNA |
CTD |
PMID:15913539 |
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NCBI chr 6:31,652,404...31,658,210
Ensembl chr 6:31,652,416...31,658,210
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G |
APP |
amyloid beta precursor protein |
multiple interactions increases uptake affects abundance |
ISO |
2,4-Dinitrophenol affects the reaction [APP protein affects the abundance of Calcium]; 3-nitrophenol affects the reaction [APP protein affects the abundance of Calcium]; 4-anisidine affects the reaction [APP protein affects the abundance of Calcium] APP protein modified form results in increased uptake of Calcium; APP protein results in increased uptake of Calcium Calcium deficiency inhibits the reaction [APP protein modified form results in increased uptake of Calcium]; EDN3 protein inhibits the reaction [APP protein results in increased uptake of Calcium]; Flurbiprofen inhibits the reaction [APP protein results in increased uptake of Calcium]; Ibuprofen inhibits the reaction [APP protein results in increased uptake of Calcium]; Indomethacin inhibits the reaction [APP protein results in increased uptake of Calcium]; Nimodipine inhibits the reaction [APP protein results in increased uptake of Calcium]; Ruthenium Red inhibits the reaction [APP protein modified form results in increased uptake of Calcium]; Salicylates inhibits the reaction [APP protein results in increased uptake of Calcium]; sulindac sulfide inhibits the reaction [APP protein results in increased uptake of Calcium] |
CTD |
PMID:12383957 PMID:18648507 PMID:18949129 PMID:24457011 |
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NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128
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G |
ARRB2 |
arrestin beta 2 |
multiple interactions |
ISO |
ARRB2 protein affects the abundance of and affects the localization of Calcium ARRB2 promotes the reaction [carvedilol results in increased uptake of Calcium] |
CTD |
PMID:16210646 PMID:21078978 |
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NCBI chr17:4,710,632...4,721,497
Ensembl chr17:4,710,596...4,721,499
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G |
ATP1A1 |
ATPase Na+/K+ transporting subunit alpha 1 |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of ATP1A1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 1:116,373,244...116,404,774
Ensembl chr 1:116,372,668...116,410,261
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G |
ATP1B1 |
ATPase Na+/K+ transporting subunit beta 1 |
multiple interactions |
ISO |
Calcium affects the reaction [Ouabain results in increased expression of ATP1B1 mRNA] |
CTD |
PMID:11204457 |
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NCBI chr 1:169,106,690...169,132,719
Ensembl chr 1:169,105,697...169,310,992
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G |
ATP2A1 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 |
affects transport multiple interactions |
ISO |
ATP2A1 protein affects the transport of Calcium [Phenols results in decreased activity of ATP2A1 protein] which results in decreased transport of Calcium |
CTD |
PMID:11230109 PMID:18773882 |
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NCBI chr16:28,878,488...28,904,466
Ensembl chr16:28,878,405...28,904,466
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G |
ATP2A2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
affects abundance multiple interactions affects transport affects uptake affects export |
ISO EXP |
ATP2A2 protein affects the abundance of Calcium Calcium promotes the reaction [Clioquinol results in decreased expression of ATP2A2 mRNA]; Calcium promotes the reaction [Clioquinol results in decreased expression of ATP2A2 protein] ATP2A2 protein affects the transport of Calcium [[Phenylephrine results in increased activity of SLC9A1 protein] which results in increased transport of Calcium] which results in increased expression of ATP2A2 protein; [Phenylephrine results in decreased expression of ATP2A2 protein] which results in decreased transport of Calcium; [Thapsigargin results in decreased activity of ATP2A2 protein] which results in decreased transport of Calcium Calcium promotes the reaction [Clioquinol results in decreased expression of ATP2A2 mRNA]; Calcium promotes the reaction [Clioquinol results in decreased expression of ATP2A2 protein]; PPP3R1 gene mutant form inhibits the reaction [ATP2A2 protein affects the transport of Calcium] ATP2A2 protein alternative form affects the uptake of Calcium ATP2A2 protein alternative form affects the export of Calcium |
CTD |
PMID:11679415 PMID:16236312 PMID:17287366 PMID:19244478 PMID:19328205 PMID:19700627 PMID:33511738 More...
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NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093
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G |
ATP2B1 |
ATPase plasma membrane Ca2+ transporting 1 |
multiple interactions increases export |
EXP |
caloxin 1b1 inhibits the reaction [ATP2B1 protein results in increased export of Calcium] |
CTD |
PMID:16452157 |
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NCBI chr12:89,588,049...89,709,366
Ensembl chr12:89,588,049...89,709,366
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G |
ATP2B4 |
ATPase plasma membrane Ca2+ transporting 4 |
increases export multiple interactions |
EXP |
ATP2B4 protein results in increased export of Calcium caloxin 1b1 inhibits the reaction [ATP2B4 protein results in increased export of Calcium] |
CTD |
PMID:16452157 |
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NCBI chr 1:203,626,832...203,744,081
Ensembl chr 1:203,626,832...203,744,081
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G |
ATP8B1 |
ATPase phospholipid transporting 8B1 |
multiple interactions |
ISO |
Calcium inhibits the reaction [ATP8B1 protein results in increased transport of Phosphatidylserines] |
CTD |
PMID:11584374 |
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NCBI chr18:57,646,426...57,803,315
Ensembl chr18:57,646,426...57,803,315
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G |
AVP |
arginine vasopressin |
multiple interactions increases uptake increases abundance |
ISO |
1-Butanol inhibits the reaction [AVP protein results in increased abundance of Calcium]; 2-(4-amylcinnamoyl)amino-4-chlorobenzoic acid inhibits the reaction [AVP protein results in increased abundance of Calcium]; [[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; [[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein; [AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium; [AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium; AVP protein results in increased import of and results in increased abundance of Calcium; Carvedilol inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium]; Chromium affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; Chromium affects the reaction [INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; chromium tripicolinate affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; chromium tripicolinate affects the reaction [INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; INS1 protein affects the reaction [Chromium affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; INS1 protein affects the reaction [chromium tripicolinate affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; Nicardipine inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium]; Nifedipine inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium] |
CTD |
PMID:9446840 PMID:11356622 PMID:11553362 PMID:14711191 PMID:21039959 |
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NCBI chr20:3,082,556...3,084,724
Ensembl chr20:3,082,556...3,084,724
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G |
AVPR1A |
arginine vasopressin receptor 1A |
multiple interactions |
ISO |
[[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; [[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein; [AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium; [NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium; Carbachol promotes the reaction [[NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium]; Nicardipine inhibits the reaction [[NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium]; Nicardipine inhibits the reaction [Carbachol promotes the reaction [[NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium]] |
CTD |
PMID:11553362 PMID:12646291 |
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NCBI chr12:63,142,759...63,151,201
Ensembl chr12:63,142,759...63,151,201
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G |
AVPR2 |
arginine vasopressin receptor 2 |
affects expression |
ISO |
Calcium affects the expression of AVPR2 mRNA |
CTD |
PMID:15913539 |
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NCBI chr X:153,902,625...153,907,166
Ensembl chr X:153,902,531...153,907,166
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G |
AXIN1 |
axin 1 |
affects expression |
ISO |
Calcium affects the expression of AXIN1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr16:287,440...352,723
Ensembl chr16:287,440...352,723
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G |
BAD |
BCL2 associated agonist of cell death |
affects expression |
ISO |
Calcium affects the expression of BAD mRNA |
CTD |
PMID:15913539 |
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NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
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G |
BDKRB1 |
bradykinin receptor B1 |
multiple interactions |
EXP ISO |
2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [[kallidin, des-Arg(10)- results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]; [kallidin, des-Arg(10)- results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium; Sodium affects the reaction [[kallidin, des-Arg(10)- results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium] [kallidin, des-Arg(10)- binds to and results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium; bradykinin, Lys-Leu(8)-desArg(9)- inhibits the reaction [[kallidin, des-Arg(10)- binds to and results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]; Indomethacin inhibits the reaction [[kallidin, des-Arg(10)- binds to and results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium] |
CTD |
PMID:15703175 PMID:22554775 |
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NCBI chr14:96,256,210...96,264,763
Ensembl chr14:96,256,210...96,268,967
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G |
BDKRB2 |
bradykinin receptor B2 |
multiple interactions |
EXP ISO |
BDKRB2 protein affects the reaction [KNG1 protein affects the abundance of Calcium] BDKRB2 protein affects the reaction [pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]] |
CTD |
PMID:16473424 PMID:18054572 |
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NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166
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G |
BDNF |
brain derived neurotrophic factor |
multiple interactions increases transport |
ISO EXP |
[Cadmium results in decreased transport of Calcium] inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein]; Calcium affects the reaction [Oxygen deficiency results in increased secretion of BDNF protein] BDNF protein results in increased transport of Calcium 3,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]; 3,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide promotes the reaction [Tetrodotoxin inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]]; Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]; Tetrodotoxin inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]] |
CTD |
PMID:16553631 PMID:26095976 |
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NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
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G |
BEST1 |
bestrophin 1 |
increases activity multiple interactions |
ISO EXP |
Calcium results in increased activity of BEST1 protein [PAR-1-activating peptide results in increased abundance of Calcium] which results in increased activity of BEST1 protein |
CTD |
PMID:19828819 PMID:25573456 |
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NCBI chr11:61,949,821...61,965,515
Ensembl chr11:61,950,063...61,965,515
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G |
BMP4 |
bone morphogenetic protein 4 |
affects expression multiple interactions |
ISO EXP |
Calcium affects the expression of BMP4 mRNA [Calcium binds to MGP protein] which binds to and results in decreased activity of BMP4 protein; [Edetic Acid inhibits the reaction [Calcium binds to MGP protein]] inhibits the reaction [MGP protein binds to BMP4 protein] |
CTD |
PMID:15913539 PMID:18369157 |
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NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
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G |
BTK |
Bruton tyrosine kinase |
affects transport |
ISO |
BTK protein affects the transport of Calcium |
CTD |
PMID:12848851 |
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NCBI chr X:101,349,450...101,390,796
Ensembl chr X:101,349,338...101,390,796
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G |
C5 |
complement C5 |
multiple interactions |
EXP ISO |
[C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium; resveratrol inhibits the reaction [[C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium] |
CTD |
PMID:19284563 PMID:19346296 |
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NCBI chr 9:120,952,335...121,074,865
Ensembl chr 9:120,932,987...121,075,195
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G |
CA4 |
carbonic anhydrase 4 |
affects expression |
ISO |
Calcium affects the expression of CA4 mRNA |
CTD |
PMID:15913539 |
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NCBI chr17:60,149,973...60,179,021
Ensembl chr17:60,149,942...60,170,899
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G |
CACNA1A |
calcium voltage-gated channel subunit alpha1 A |
increases transport multiple interactions |
ISO |
CACNA1A protein results in increased transport of Calcium Allethrins inhibits the reaction [CACNA1A protein results in increased transport of Calcium] |
CTD |
PMID:14634047 |
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NCBI chr19:13,206,442...13,506,479
Ensembl chr19:13,206,442...13,633,025
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G |
CACNA1B |
calcium voltage-gated channel subunit alpha1 B |
multiple interactions decreases uptake increases transport |
ISO |
decamethrin inhibits the reaction [CACNA1B protein results in increased transport of Calcium]; decamethrin promotes the reaction [CACNA1B gene mutant form results in increased transport of Calcium] CACNA1B protein alternative form results in decreased uptake of Calcium |
CTD |
PMID:18383452 PMID:22891239 |
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NCBI chr 9:137,877,782...138,124,619
Ensembl chr 9:137,877,782...138,124,624
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G |
CACNA1C |
calcium voltage-gated channel subunit alpha1 C |
increases transport multiple interactions |
EXP ISO |
CACNA1C protein results in increased transport of Calcium [CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium; [CACNA2D4 protein binds to CACNA1C protein binds to CACNB3 protein] which results in increased transport of Calcium; CACNA2D4 protein promotes the reaction [[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium] Allethrins inhibits the reaction [CACNA1C protein results in increased transport of Calcium] |
CTD |
PMID:12181424 PMID:14634047 PMID:15299022 |
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NCBI chr12:1,970,780...2,697,950
Ensembl chr12:1,970,772...2,697,950
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G |
CACNA1D |
calcium voltage-gated channel subunit alpha1 D |
affects transport multiple interactions |
ISO |
CACNA1D protein affects the transport of Calcium CACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Calcium] [CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium; [CACNA1D protein results in increased uptake of Calcium] which affects the localization of SLC2A2 protein; [CACNA1D protein results in increased uptake of Calcium] which results in increased phosphorylation of MYL9 protein; CACNA2D1 protein promotes the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]; gabapentin affects the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]; SLC5A1 protein affects the reaction [CACNA1D protein results in increased uptake of Calcium] |
CTD |
PMID:15357422 PMID:17272349 PMID:19796812 PMID:27798183 |
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NCBI chr 3:53,494,611...53,813,733
Ensembl chr 3:53,328,963...53,813,733
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G |
CACNA1E |
calcium voltage-gated channel subunit alpha1 E |
increases transport multiple interactions |
EXP ISO |
CACNA1E protein results in increased transport of Calcium Calcium inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]] Cadmium inhibits the reaction [CACNA1E protein results in increased transport of Calcium]; Nickel inhibits the reaction [CACNA1E protein results in increased transport of Calcium] |
CTD |
PMID:10627594 PMID:10669483 PMID:12663092 |
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NCBI chr 1:181,317,699...181,808,084
Ensembl chr 1:181,317,690...181,813,262
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G |
CACNA1F |
calcium voltage-gated channel subunit alpha1 F |
increases transport |
ISO |
CACNA1F protein results in increased transport of Calcium |
CTD |
PMID:14744918 |
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NCBI chr X:49,205,063...49,233,340
Ensembl chr X:49,205,063...49,233,371
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G |
CACNA1G |
calcium voltage-gated channel subunit alpha1 G |
increases transport multiple interactions |
ISO |
CACNA1G protein results in increased transport of Calcium Allethrins inhibits the reaction [CACNA1G protein results in increased transport of Calcium] CACNG2 protein affects the reaction [CACNA1G protein results in increased transport of Calcium]; CACNG4 protein affects the reaction [CACNA1G protein results in increased transport of Calcium]; CACNG5 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] |
CTD |
PMID:10734232 PMID:11073957 PMID:14634047 |
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NCBI chr17:50,560,715...50,627,474
Ensembl chr17:50,560,715...50,627,474
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G |
CACNA1H |
calcium voltage-gated channel subunit alpha1 H |
increases transport multiple interactions |
EXP ISO |
CACNA1H protein results in increased transport of Calcium Amiloride inhibits the reaction [CACNA1H protein results in increased transport of Calcium]; Nickel inhibits the reaction [CACNA1H protein results in increased transport of Calcium] Amiloride inhibits the reaction [CACNA1H protein results in increased transport of Calcium]; Mibefradil inhibits the reaction [CACNA1H protein results in increased transport of Calcium]; Nickel inhibits the reaction [CACNA1H protein results in increased transport of Calcium] |
CTD |
PMID:9930755 PMID:11073957 PMID:11897840 |
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NCBI chr16:1,153,106...1,221,768
Ensembl chr16:1,153,103...1,224,169
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G |
CACNA1I |
calcium voltage-gated channel subunit alpha1 I |
increases transport |
ISO |
CACNA1I protein results in increased transport of Calcium |
CTD |
PMID:11073957 |
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NCBI chr22:39,570,753...39,689,735
Ensembl chr22:39,570,753...39,689,735
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G |
CACNA2D1 |
calcium voltage-gated channel auxiliary subunit alpha2delta 1 |
multiple interactions increases transport |
ISO |
[gabapentin results in decreased activity of CACNA2D1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]; CACNA2D1 protein affects the reaction [Potassium Chloride results in increased transport of Calcium] CACNA2D1 protein promotes the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium] CACNA2D1 protein results in increased transport of Calcium |
CTD |
PMID:15474003 PMID:17442347 PMID:17881535 PMID:19796812 |
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NCBI chr 7:81,946,444...82,443,956
Ensembl chr 7:81,946,444...82,443,956
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G |
CACNA2D2 |
calcium voltage-gated channel auxiliary subunit alpha2delta 2 |
affects transport multiple interactions |
ISO |
CACNA2D2 protein affects the transport of Calcium CACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Calcium] |
CTD |
PMID:14660671 PMID:27798183 |
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NCBI chr 3:50,362,613...50,504,244
Ensembl chr 3:50,362,613...50,504,244
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G |
CACNA2D4 |
calcium voltage-gated channel auxiliary subunit alpha2delta 4 |
multiple interactions |
EXP |
[CACNA2D4 protein binds to CACNA1C protein binds to CACNB3 protein] which results in increased transport of Calcium; CACNA2D4 protein promotes the reaction [[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium] |
CTD |
PMID:12181424 |
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NCBI chr12:1,791,963...1,918,652
Ensembl chr12:1,791,963...1,918,666
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G |
CACNB3 |
calcium voltage-gated channel auxiliary subunit beta 3 |
multiple interactions |
EXP ISO |
[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium; [CACNA2D4 protein binds to CACNA1C protein binds to CACNB3 protein] which results in increased transport of Calcium; CACNA2D4 protein promotes the reaction [[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium] [CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium; CACNA2D1 protein promotes the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]; gabapentin affects the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium] |
CTD |
PMID:12181424 PMID:19796812 |
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NCBI chr12:48,814,480...48,828,941
Ensembl chr12:48,813,794...48,828,941
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G |
CACNG2 |
calcium voltage-gated channel auxiliary subunit gamma 2 |
multiple interactions |
ISO |
CACNG2 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] |
CTD |
PMID:10734232 |
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NCBI chr22:36,560,857...36,703,752
Ensembl chr22:36,560,857...36,703,752
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G |
CACNG4 |
calcium voltage-gated channel auxiliary subunit gamma 4 |
multiple interactions |
ISO |
CACNG4 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] |
CTD |
PMID:10734232 |
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NCBI chr17:66,964,707...67,033,398
Ensembl chr17:66,964,707...67,033,398
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G |
CACNG5 |
calcium voltage-gated channel auxiliary subunit gamma 5 |
multiple interactions |
ISO |
CACNG5 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] |
CTD |
PMID:10734232 |
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NCBI chr17:66,835,117...66,894,751
Ensembl chr17:66,835,117...66,894,751
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G |
CALB1 |
calbindin 1 |
affects expression |
ISO |
Calcium affects the expression of CALB1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 8:90,058,608...90,082,879
Ensembl chr 8:90,058,608...90,095,475
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G |
CALCA |
calcitonin related polypeptide alpha |
multiple interactions increases expression |
ISO EXP |
rimabotulinumtoxinB inhibits the reaction [[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein]; rimabotulinumtoxinB inhibits the reaction [[Potassium co-treated with Calcium] results in increased secretion of CALCA protein] Calcium promotes the reaction [Lipopolysaccharides results in increased expression of CALCA mRNA] Calcium results in increased expression of CALCA mRNA Calcium results in increased expression of CALCA protein [Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein; [KNG1 protein alternative form co-treated with Calcium] results in increased secretion of CALCA protein; [Potassium co-treated with Calcium] results in increased secretion of CALCA protein; [Sumatriptan results in increased abundance of Calcium] inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA]; botulinum toxin type D inhibits the reaction [[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein]; botulinum toxin type D inhibits the reaction [[Potassium co-treated with Calcium] results in increased secretion of CALCA protein]; Botulinum Toxins, Type A inhibits the reaction [[Potassium co-treated with Calcium] results in increased secretion of CALCA protein]; Calcium affects the reaction [Capsaicin inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Calcium affects the reaction [Capsaicin inhibits the reaction [mustard oil results in increased secretion of CALCA protein]]; Calcium affects the reaction [mustard oil inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Calcium deficiency inhibits the reaction [safranal results in increased secretion of CALCA protein]; Calcium inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA] |
CTD |
PMID:2470235 PMID:12574409 PMID:17590514 PMID:17666428 PMID:20682585 PMID:30636360 More...
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NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354
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G |
CALM1 |
calmodulin 1 |
multiple interactions affects binding |
EXP ISO |
Calcium affects the folding of [CALM1 protein binds to RYR1 protein modified form]; Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein] Calcium binds to CALM1 protein [Calcium binds to CALM1 protein] promotes the reaction [NOS1 protein results in increased chemical synthesis of Nitric Oxide]; [Calcium binds to CALM1 protein] which binds to and affects the folding of and results in increased activity of NOS1 protein; Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]; Calcium affects the reaction [CALM1 protein modified form binds to and affects the activity of RYR1 protein]; Calcium binds to and affects the folding of CALM1 protein |
CTD |
PMID:15381065 PMID:15628869 PMID:17098364 |
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NCBI chr14:90,396,502...90,408,268
Ensembl chr14:90,396,502...90,408,268
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G |
CALR |
calreticulin |
affects response to substance multiple interactions |
ISO |
CALR protein affects the susceptibility to Calcium CALR protein promotes the reaction [KNG1 protein modified form results in increased abundance of Calcium] |
CTD |
PMID:7961812 |
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NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489
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G |
CAMK2D |
calcium/calmodulin dependent protein kinase II delta |
affects expression multiple interactions |
ISO EXP |
Calcium affects the expression of CAMK2D mRNA [Ionomycin co-treated with Calcium co-treated with CAMK2D protein] results in increased activity of TRPM4 protein |
CTD |
PMID:15913539 PMID:33392831 |
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NCBI chr 4:113,451,032...113,761,738
Ensembl chr 4:113,418,054...113,761,927
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G |
CAMKK2 |
calcium/calmodulin dependent protein kinase kinase 2 |
multiple interactions |
EXP |
CAMKK2 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:28634229 |
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NCBI chr12:121,237,692...121,297,819
Ensembl chr12:121,237,675...121,298,308
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G |
CAPN1 |
calpain 1 |
multiple interactions increases cleavage increases activity |
EXP ISO |
[Caffeine co-treated with Alprazolam] promotes the reaction [Calcium results in increased activity of CAPN1 protein]; [Calcium co-treated with CAPN1 protein] results in increased degradation of TP73 protein modified form; [sodium arsenite results in increased abundance of Arsenic] promotes the reaction [[Calcium results in increased cleavage of CAPN1 protein] which results in increased degradation of CAPN1 protein] calpain inhibitor III inhibits the reaction [Calcium results in increased activity of CAPN1 protein] |
CTD |
PMID:19490937 PMID:21516125 PMID:21985864 PMID:31398423 |
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NCBI chr11:65,181,373...65,212,006
Ensembl chr11:65,180,566...65,212,006
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G |
CASP3 |
caspase 3 |
multiple interactions |
ISO EXP |
[Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in increased expression of CASP3 mRNA]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in increased expression of CASP3 mRNA]; Calcium affects the reaction [sodium arsenite results in increased expression of CASP3 mRNA] Calcium deficiency inhibits the reaction [Dasatinib results in increased activity of CASP3 protein]; Calcium deficiency inhibits the reaction [Ionomycin results in increased activity of CASP3 protein] |
CTD |
PMID:24184500 PMID:29803841 |
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NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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G |
CASP9 |
caspase 9 |
multiple interactions |
ISO |
[Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in increased expression of CASP9 mRNA]]; Calcium affects the reaction [sodium arsenite results in increased expression of CASP9 mRNA] |
CTD |
PMID:24184500 |
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NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
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G |
CASR |
calcium sensing receptor |
increases phosphorylation multiple interactions increases uptake increases activity affects expression decreases response to substance increases response to substance |
EXP ISO |
Calcium results in increased phosphorylation of CASR protein [Aluminum binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Calcium binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Calcium binds to and results in increased activity of CASR protein] which results in increased abundance of Inositol Phosphates; [Gadolinium binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Magnesium binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Neomycin binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; Calcium binds to and results in increased activity of CASR protein; Gadolinium inhibits the reaction [Calcium binds to and results in increased activity of CASR protein] CASR protein results in increased uptake of Calcium Calcium results in increased activity of CASR protein 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [CASR protein results in increased uptake of Calcium]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [CASR protein results in increased uptake of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]; 2-aminoethoxydiphenyl borate inhibits the reaction [CASR protein results in increased uptake of Calcium]; [2-quinoxaline-carboxamide-N-adamantan-1-yl binds to and results in decreased activity of CASR protein] inhibits the reaction [Nickel results in increased abundance of Calcium]; [Calcium binds to and results in increased activity of CASR protein] which results in increased uptake of Calcium; [CASR protein mutant form results in increased susceptibility to Calcium] which results in increased abundance of Inositol 1,4,5-Trisphosphate; [Spermine binds to and results in increased activity of CASR protein] which results in increased uptake of Calcium; bisindolylmaleimide I inhibits the reaction [NPS R-467 promotes the reaction [Calcium results in increased phosphorylation of CASR protein]]; Calcium Chloride promotes the reaction [Calcium results in increased phosphorylation of CASR protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of WNT5A protein]; CASR protein affects the reaction [Nickel results in increased abundance of Calcium]; CASR protein promotes the reaction [TRPC6 protein results in increased uptake of Calcium]; chelerythrine inhibits the reaction [CASR protein results in increased uptake of Calcium]; Flufenamic Acid promotes the reaction [CASR protein results in increased uptake of Calcium]; Lanthanum inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]; Lanthanum inhibits the reaction [CASR protein results in increased uptake of Calcium]; methyl-beta-cyclodextrin inhibits the reaction [CASR protein results in increased uptake of Calcium]; N-(2-chlorophenylpropyl)-1-(3-methoxyphenyl)ethylamine affects the reaction [CASR gene mutant form results in increased susceptibility to Calcium]; N-(2-chlorophenylpropyl)-1-(3-methoxyphenyl)ethylamine promotes the reaction [CASR protein results in increased susceptibility to Calcium]; NPS R-467 promotes the reaction [Calcium results in increased phosphorylation of CASR protein]; Pertussis Toxin inhibits the reaction [CASR protein results in increased uptake of Calcium] Calcium affects the expression of CASR mRNA; Calcium affects the expression of CASR protein CASR protein mutant form results in decreased susceptibility to Calcium CASR gene mutant form results in increased susceptibility to Calcium; CASR protein mutant form results in increased susceptibility to Calcium |
CTD |
PMID:7874174 PMID:9011580 PMID:10231437 PMID:11071898 PMID:11089548 PMID:11701698 PMID:15788476 PMID:17041782 PMID:17376781 PMID:19781536 PMID:21562303 PMID:24658506 More...
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NCBI chr 3:122,183,668...122,291,629
Ensembl chr 3:122,183,668...122,291,629
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G |
CAT |
catalase |
multiple interactions |
EXP ISO |
CAT protein inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; CAT protein inhibits the reaction [Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]] [Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in decreased activity of CAT protein]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in decreased activity of CAT protein]; [Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of CAT protein]; Calcium affects the reaction [sodium arsenite results in decreased activity of CAT protein] |
CTD |
PMID:21127073 PMID:22534743 PMID:24184500 |
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NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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G |
CAV1 |
caveolin 1 |
affects transport |
ISO |
CAV1 protein affects the transport of Calcium |
CTD |
PMID:16428350 |
|
NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179
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G |
CAV3 |
caveolin 3 |
multiple interactions |
EXP |
CAV3 protein affects the reaction [Potassium Chloride results in increased uptake of Calcium] |
CTD |
PMID:21294223 |
|
NCBI chr 3:8,733,802...8,746,758
Ensembl chr 3:8,733,802...8,841,808
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G |
CBFB |
core-binding factor subunit beta |
affects expression |
ISO |
Calcium affects the expression of CBFB mRNA |
CTD |
PMID:15913539 |
|
NCBI chr16:67,029,149...67,101,058
Ensembl chr16:67,028,984...67,101,058
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G |
CCL11 |
C-C motif chemokine ligand 11 |
increases uptake |
EXP |
CCL11 protein results in increased uptake of Calcium |
CTD |
PMID:10984371 |
|
NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334
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G |
CCL13 |
C-C motif chemokine ligand 13 |
increases uptake |
EXP |
CCL13 protein results in increased uptake of Calcium |
CTD |
PMID:10984371 |
|
NCBI chr17:34,356,480...34,358,610
Ensembl chr17:34,356,480...34,358,610
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G |
CCL2 |
C-C motif chemokine ligand 2 |
multiple interactions increases abundance increases uptake |
EXP |
montelukast inhibits the reaction [CCL2 protein results in increased abundance of Calcium]; Piperidines analog inhibits the reaction [CCL2 protein results in increased uptake of Calcium]; resveratrol inhibits the reaction [CCL2 protein affects the localization of Calcium] |
CTD |
PMID:10843593 PMID:10984371 PMID:16212921 PMID:16771778 |
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NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
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G |
CCL3 |
C-C motif chemokine ligand 3 |
multiple interactions |
EXP |
resveratrol inhibits the reaction [CCL3 protein affects the localization of Calcium] |
CTD |
PMID:16212921 |
|
NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
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G |
CCL5 |
C-C motif chemokine ligand 5 |
increases uptake |
EXP |
CCL5 protein results in increased uptake of Calcium |
CTD |
PMID:10984371 |
|
NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
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G |
CCL7 |
C-C motif chemokine ligand 7 |
increases uptake multiple interactions |
EXP |
CCL7 protein results in increased uptake of Calcium Piperidines analog inhibits the reaction [CCL7 protein results in increased uptake of Calcium] |
CTD |
PMID:10843593 PMID:10984371 |
|
NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242
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G |
CCND1 |
cyclin D1 |
affects expression increases expression |
ISO EXP |
Calcium affects the expression of CCND1 mRNA Calcium results in increased expression of CCND1 mRNA |
CTD |
PMID:15913539 PMID:24658506 |
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NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
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G |
CCR10 |
C-C motif chemokine receptor 10 |
affects abundance |
EXP |
CCR10 protein affects the abundance of Calcium |
CTD |
PMID:12055238 |
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NCBI chr17:42,678,889...42,681,843
Ensembl chr17:42,678,889...42,683,917
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G |
CCR4 |
C-C motif chemokine receptor 4 |
affects abundance |
EXP |
CCR4 protein affects the abundance of Calcium |
CTD |
PMID:12055238 |
|
NCBI chr 3:32,951,644...32,956,349
Ensembl chr 3:32,951,644...32,956,349
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G |
CCR8 |
C-C motif chemokine receptor 8 |
affects abundance |
EXP |
CCR8 protein affects the abundance of Calcium |
CTD |
PMID:12055238 |
|
NCBI chr 3:39,329,709...39,333,680
Ensembl chr 3:39,329,709...39,333,680
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G |
CCR9 |
C-C motif chemokine receptor 9 |
affects abundance |
EXP |
CCR9 protein affects the abundance of Calcium |
CTD |
PMID:12055238 |
|
NCBI chr 3:45,886,064...45,903,174
Ensembl chr 3:45,884,425...45,903,174
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G |
CD28 |
CD28 molecule |
multiple interactions increases abundance |
EXP |
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [CD28 protein results in increased abundance of Calcium]; 2-aminoethoxydiphenylborane inhibits the reaction [CD28 protein results in increased abundance of Calcium]; 5-diisopropoxyphosphoryl-5-methyl-1-pyrroline-N-oxide inhibits the reaction [CD28 protein results in increased abundance of Calcium]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [CD28 protein results in increased abundance of Calcium] |
CTD |
PMID:14607919 |
|
NCBI chr 2:203,706,482...203,738,912
Ensembl chr 2:203,706,475...203,738,912
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G |
CD38 |
CD38 molecule |
multiple interactions |
ISO |
CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]; CD38 protein inhibits the reaction [CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]] |
CTD |
PMID:20200208 |
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NCBI chr 4:15,778,328...15,853,232
Ensembl chr 4:15,778,275...15,853,232
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G |
CDC42 |
cell division cycle 42 |
multiple interactions |
ISO |
Calcium promotes the reaction [PAFAH1B1 protein binds to IQGAP1 protein binds to CDC42 protein] |
CTD |
PMID:16369480 |
|
NCBI chr 1:22,052,709...22,101,360
Ensembl chr 1:22,052,627...22,101,360
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G |
CDC42BPB |
CDC42 binding protein kinase beta |
affects expression |
ISO |
Calcium affects the expression of CDC42BPB mRNA |
CTD |
PMID:15913539 |
|
NCBI chr14:102,932,380...103,057,549
Ensembl chr14:102,932,380...103,057,549
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G |
CDK5R1 |
cyclin dependent kinase 5 regulatory subunit 1 |
increases cleavage multiple interactions |
EXP |
Calcium results in increased cleavage of CDK5R1 protein calpeptin inhibits the reaction [Calcium results in increased cleavage of CDK5R1 protein] |
CTD |
PMID:18242949 |
|
NCBI chr17:32,486,993...32,491,253
Ensembl chr17:32,486,993...32,491,253
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G |
CEBPB |
CCAAT enhancer binding protein beta |
affects expression |
ISO |
Calcium affects the expression of CEBPB mRNA |
CTD |
PMID:15913539 |
|
NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668
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G |
CERK |
ceramide kinase |
multiple interactions |
EXP |
Calcium affects the reaction [CERK protein results in increased phosphorylation of Ceramides] |
CTD |
PMID:16269826 |
|
NCBI chr22:46,684,410...46,738,252
Ensembl chr22:46,684,410...46,738,252
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G |
CFB |
complement factor B |
multiple interactions |
ISO |
CFD protein affects the reaction [[cobra venom factor co-treated with Magnesium co-treated with Calcium] results in increased cleavage of CFB protein] |
CTD |
PMID:11724962 |
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NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,086
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G |
CFD |
complement factor D |
multiple interactions |
ISO |
CFD protein affects the reaction [[cobra venom factor co-treated with Magnesium co-treated with Calcium] results in increased cleavage of CFB protein] |
CTD |
PMID:11724962 |
|
NCBI chr19:859,664...863,641
Ensembl chr19:859,453...867,884
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G |
CFL1 |
cofilin 1 |
multiple interactions |
EXP |
[Capsaicin results in decreased phosphorylation of and results in increased activity of CFL1 protein] which results in increased import of Calcium |
CTD |
PMID:17303079 |
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NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026
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G |
CHRM1 |
cholinergic receptor muscarinic 1 |
multiple interactions |
EXP ISO |
[Acetylcholine results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; [Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; [Pilocarpine results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; CHRM1 protein promotes the reaction [Methacholine Compounds results in increased abundance of Calcium] 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; 1-oleoyl-2-acetylglycerol promotes the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; [Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; Atropine inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Flufenamic Acid inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Gadolinium inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Lanthanum inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Pirenzepine inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Thapsigargin inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium] [[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; [[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein |
CTD |
PMID:11527950 PMID:11553362 PMID:12456425 PMID:18316702 |
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NCBI chr11:62,908,679...62,921,878
Ensembl chr11:62,908,679...62,921,807
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G |
CHRNA4 |
cholinergic receptor nicotinic alpha 4 subunit |
multiple interactions |
ISO |
[CHRNA4 protein co-treated with CHRNB2 protein mutant form] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein co-treated with CHRNB2 protein] affects the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein mutant form co-treated with CHRNB2 protein] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine] |
CTD |
PMID:12754307 |
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NCBI chr20:63,343,223...63,361,349
Ensembl chr20:63,343,223...63,378,401
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G |
CHRNA7 |
cholinergic receptor nicotinic alpha 7 subunit |
multiple interactions |
EXP ISO |
[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium; [[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] which results in increased uptake of Calcium] inhibits the reaction [CHRNA7 protein results in decreased susceptibility to Okadaic Acid]; [Acetylcholine results in increased activity of CHRNA7 protein] which results in increased uptake of Calcium; [Bungarotoxins binds to and results in increased activity of CHRNA7 protein] which results in increased transport of Calcium; [methyllycaconitine binds to and results in increased activity of CHRNA7 protein] which results in increased transport of Calcium; [Nicotine results in increased activity of CHRNA7 protein] which results in increased transport of Calcium; [PNU-282987 binds to and results in increased activity of CHRNA7 protein] which results in increased uptake of Calcium; Bungarotoxins inhibits the reaction [[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium]; Mecamylamine inhibits the reaction [[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium]; methyllycaconitine inhibits the reaction [[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium]; methyllycaconitine promotes the reaction [[Nicotine results in increased activity of CHRNA7 protein] which results in increased transport of Calcium] |
CTD |
PMID:17709503 PMID:21051662 PMID:21715663 |
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NCBI chr15:32,030,483...32,173,018
Ensembl chr15:31,923,438...32,173,018
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G |
CHRNB2 |
cholinergic receptor nicotinic beta 2 subunit |
multiple interactions |
EXP ISO |
[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium; alpha-conotoxin MII inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium]; Calcium affects the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased susceptibility to Okadaic Acid]; Dihydro-beta-Erythroidine inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium]; Mecamylamine inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium] [CHRNA4 protein co-treated with CHRNB2 protein mutant form] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein co-treated with CHRNB2 protein] affects the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein mutant form co-treated with CHRNB2 protein] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine] |
CTD |
PMID:12754307 PMID:21715663 |
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NCBI chr 1:154,567,778...154,580,013
Ensembl chr 1:154,567,778...154,580,013
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G |
CITED2 |
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 |
affects expression |
ISO |
Calcium affects the expression of CITED2 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 6:139,371,807...139,374,648
Ensembl chr 6:139,371,807...139,374,648
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G |
CLN8 |
CLN8 transmembrane ER and ERGIC protein |
multiple interactions |
ISO |
CLN8 protein affects the reaction [[Ionomycin co-treated with Calcium] results in increased transport of D-Aspartic Acid]; CLN8 protein affects the reaction [[Potassium Chloride co-treated with Calcium] results in increased transport of D-Aspartic Acid] |
CTD |
PMID:22302580 |
|
NCBI chr 8:1,753,059...1,786,570
Ensembl chr 8:1,755,778...1,801,711
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G |
CNNM4 |
cyclin and CBS domain divalent metal cation transport mediator 4 |
affects expression |
ISO |
Calcium affects the expression of CNNM4 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 2:96,760,902...96,811,874
Ensembl chr 2:96,760,902...96,811,874
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G |
CNR1 |
cannabinoid receptor 1 |
multiple interactions |
ISO |
[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein] affects the reaction [Potassium Chloride results in increased transport of Calcium]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] affects the reaction [Potassium Chloride results in increased transport of Calcium]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium results in increased transport of Calcium]; Calcium affects the reaction [Potassium Chloride results in decreased expression of CNR1 mRNA]; Calcium affects the reaction [Potassium Chloride results in decreased expression of CNR1 protein]; CNR1 protein affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; CNR1 protein affects the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Pertussis Toxin inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]] |
CTD |
PMID:12421626 PMID:14973253 PMID:16412482 |
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NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347
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G |
CNR2 |
cannabinoid receptor 2 |
multiple interactions |
EXP |
CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]; Pertussis Toxin inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]]; SR 144528 inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]] |
CTD |
PMID:10617657 |
|
NCBI chr 1:23,870,515...23,913,362
Ensembl chr 1:23,870,515...23,913,362
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G |
COL18A1 |
collagen type XVIII alpha 1 chain |
affects abundance |
ISO |
COL18A1 protein affects the abundance of Calcium |
CTD |
PMID:15296943 |
|
NCBI chr21:45,405,165...45,513,720
Ensembl chr21:45,405,165...45,513,720
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G |
COL1A2 |
collagen type I alpha 2 chain |
affects abundance |
ISO |
COL1A2 protein affects the abundance of Calcium |
CTD |
PMID:10913914 |
|
NCBI chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227
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G |
CP |
ceruloplasmin |
affects binding multiple interactions |
EXP ISO |
Calcium binds to CP protein [Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of CP protein] |
CTD |
PMID:17242517 PMID:22534743 |
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NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829
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G |
CREB1 |
cAMP responsive element binding protein 1 |
affects expression multiple interactions |
ISO |
Calcium affects the expression of CREB1 mRNA [Estradiol results in increased import of Calcium] which results in increased activity of CREB1 protein; Calcium promotes the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased phosphorylation of CREB1 protein]; Calcium promotes the reaction [Dopamine results in increased phosphorylation of CREB1 protein] |
CTD |
PMID:14622123 PMID:15802184 PMID:15913539 |
|
NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
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G |
CSNK1A1 |
casein kinase 1 alpha 1 |
affects expression |
ISO |
Calcium affects the expression of CSNK1A1 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 5:149,492,982...149,551,439
Ensembl chr 5:149,492,982...149,551,471
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G |
CSNK1G3 |
casein kinase 1 gamma 3 |
affects expression |
ISO |
Calcium affects the expression of CSNK1G3 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 5:123,512,177...123,617,049
Ensembl chr 5:123,512,177...123,617,049
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G |
CTNNB1 |
catenin beta 1 |
increases expression multiple interactions |
EXP |
Calcium results in increased expression of CTNNB1 mRNA; Calcium results in increased expression of CTNNB1 protein CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein] |
CTD |
PMID:24658506 |
|
NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
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G |
CTSS |
cathepsin S |
multiple interactions |
EXP |
[CTSS protein results in increased cleavage of and results in decreased activity of CXCL10 protein] which results in decreased uptake of Calcium; [CTSS protein results in increased cleavage of and results in decreased activity of CXCL9 protein] which results in decreased uptake of Calcium; [CTSS protein results in increased cleavage of and results in increased activity of CXCL2 protein] which results in increased uptake of Calcium; [CTSS protein results in increased cleavage of and results in increased activity of CXCL5 protein] which results in increased uptake of Calcium |
CTD |
PMID:25833952 |
|
NCBI chr 1:150,730,188...150,765,778
Ensembl chr 1:150,730,079...150,765,957
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G |
CXCL1 |
C-X-C motif chemokine ligand 1 |
increases abundance multiple interactions |
ISO |
CXCL1 protein results in increased abundance of Calcium epigallocatechin gallate inhibits the reaction [CXCL1 protein results in increased abundance of Calcium] |
CTD |
PMID:9430702 PMID:15237969 |
|
NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
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G |
CXCL10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
EXP |
[CTSS protein results in increased cleavage of and results in decreased activity of CXCL10 protein] which results in decreased uptake of Calcium; [CXCL10 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium |
CTD |
PMID:25833952 |
|
NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
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G |
CXCL12 |
C-X-C motif chemokine ligand 12 |
multiple interactions increases uptake |
EXP |
resveratrol inhibits the reaction [CXCL12 protein affects the localization of Calcium] CXCL12 protein results in increased uptake of Calcium |
CTD |
PMID:10984371 PMID:11872090 PMID:16212921 |
|
NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493
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G |
CXCL2 |
C-X-C motif chemokine ligand 2 |
multiple interactions |
EXP |
[CTSS protein results in increased cleavage of and results in increased activity of CXCL2 protein] which results in increased uptake of Calcium; [CXCL2 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium |
CTD |
PMID:25833952 |
|
NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
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G |
CXCL5 |
C-X-C motif chemokine ligand 5 |
multiple interactions |
EXP |
[CTSS protein results in increased cleavage of and results in increased activity of CXCL5 protein] which results in increased uptake of Calcium; [CXCL5 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium |
CTD |
PMID:25833952 |
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NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677
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G |
CXCL8 |
C-X-C motif chemokine ligand 8 |
multiple interactions increases uptake increases abundance |
EXP |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[PLA2G1B protein results in increased abundance of Calcium] which results in increased expression of CXCL8 protein]; [CXCL8 protein binds to and results in increased activity of CXCR1 protein] which results in increased abundance of and results in increased activity of Calcium; [CXCL8 protein binds to and results in increased activity of CXCR2 protein] which results in increased abundance of and results in increased activity of Calcium; [PLA2G1B protein results in increased abundance of Calcium] which results in increased expression of CXCL8 protein; Calcium promotes the reaction [Neurotensin results in increased expression of CXCL8 mRNA]; CXCL8 protein affects the localization of and affects the abundance of Calcium; resveratrol inhibits the reaction [CXCL8 protein affects the localization of Calcium] CXCL8 protein results in increased uptake of Calcium CXCL8 protein results in increased abundance of Calcium |
CTD |
PMID:10984371 PMID:11298490 PMID:14505796 PMID:15528384 PMID:15748943 PMID:16212921 PMID:17000667 More...
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NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
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G |
CXCL9 |
C-X-C motif chemokine ligand 9 |
multiple interactions increases abundance |
EXP |
[[CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium] which results in increased expression of EGR1 mRNA; [CTSS protein results in increased cleavage of and results in decreased activity of CXCL9 protein] which results in decreased uptake of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium CXCL9 protein results in increased abundance of Calcium |
CTD |
PMID:12517959 PMID:25833952 |
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NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509
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G |
CXCR1 |
C-X-C motif chemokine receptor 1 |
multiple interactions affects abundance |
EXP |
[CXCL8 protein binds to and results in increased activity of CXCR1 protein] which results in increased abundance of and results in increased activity of Calcium CXCR1 protein affects the abundance of Calcium |
CTD |
PMID:11298490 PMID:12055238 |
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NCBI chr 2:218,162,841...218,166,962
Ensembl chr 2:218,162,841...218,166,962
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G |
CXCR2 |
C-X-C motif chemokine receptor 2 |
affects transport multiple interactions |
EXP ISO |
CXCR2 protein affects the transport of Calcium [CXCL2 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium; [CXCL5 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium; [CXCL8 protein binds to and results in increased activity of CXCR2 protein] which results in increased abundance of and results in increased activity of Calcium Excitatory Amino Acid Agonists inhibits the reaction [CXCR2 protein affects the localization of Calcium] |
CTD |
PMID:11298490 PMID:15618463 PMID:15914698 PMID:25833952 |
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NCBI chr 2:218,125,294...218,137,251
Ensembl chr 2:218,125,289...218,137,251
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G |
CXCR3 |
C-X-C motif chemokine receptor 3 |
affects abundance multiple interactions |
EXP |
CXCR3 protein affects the abundance of Calcium [[CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium] which results in increased expression of EGR1 mRNA; [CXCL10 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium |
CTD |
PMID:12055238 PMID:12517959 PMID:25833952 |
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NCBI chr X:71,615,919...71,618,511
Ensembl chr X:71,615,916...71,618,511
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G |
CXCR4 |
C-X-C motif chemokine receptor 4 |
affects abundance |
EXP |
CXCR4 protein affects the abundance of Calcium |
CTD |
PMID:12055238 |
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NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177
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G |
CXCR5 |
C-X-C motif chemokine receptor 5 |
affects abundance |
EXP |
CXCR5 protein affects the abundance of Calcium |
CTD |
PMID:12055238 |
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NCBI chr11:118,883,892...118,897,787
Ensembl chr11:118,883,892...118,897,787
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G |
CYCS |
cytochrome c, somatic |
multiple interactions increases secretion decreases secretion |
ISO |
[Calcium co-treated with Phosphates] affects the localization of CYCS protein; caffeic acid phenethyl ester inhibits the reaction [Calcium results in increased secretion of CYCS protein]; Cyclosporine inhibits the reaction [[Calcium co-treated with Phosphates] affects the localization of CYCS protein]; Nicotine inhibits the reaction [[Calcium co-treated with Phosphates] affects the localization of CYCS protein]; xestospongin C inhibits the reaction [Calcium results in decreased secretion of CYCS protein] |
CTD |
PMID:15345483 PMID:15469948 PMID:15985439 |
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NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
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G |
CYP1A1 |
cytochrome P450 family 1 subfamily A member 1 |
multiple interactions |
EXP ISO |
2-aminoethoxydiphenyl borate inhibits the reaction [[oltipraz results in increased abundance of Calcium] which results in increased expression of CYP1A1 mRNA]; [2,3,7,8-tetrachlorodibenzofuran co-treated with Calcium] results in increased expression of CYP1A1 mRNA; [oltipraz results in increased abundance of Calcium] which results in increased expression of CYP1A1 mRNA; Calcium promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; Calcium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein] |
CTD |
PMID:1979076 PMID:11959854 PMID:16237193 PMID:23298284 |
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NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
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G |
CYP1B1 |
cytochrome P450 family 1 subfamily B member 1 |
multiple interactions |
EXP ISO |
Calcium promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; Calcium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] |
CTD |
PMID:16237193 PMID:19782052 |
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NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
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G |
CYP24A1 |
cytochrome P450 family 24 subfamily A member 1 |
affects expression multiple interactions |
ISO |
Calcium affects the expression of CYP24A1 mRNA [Calcium co-treated with Calcitriol] affects the expression of CYP24A1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr20:54,143,538...54,173,986
Ensembl chr20:54,153,446...54,173,986
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G |
CYP27B1 |
cytochrome P450 family 27 subfamily B member 1 |
affects expression |
ISO |
Calcium affects the expression of CYP27B1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr12:57,762,334...57,767,078
Ensembl chr12:57,762,334...57,768,986
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G |
CYP2E1 |
cytochrome P450 family 2 subfamily E member 1 |
affects expression decreases uptake |
ISO EXP |
Calcium affects the expression of CYP2E1 mRNA CYP2E1 protein results in decreased uptake of Calcium |
CTD |
PMID:15913539 PMID:19028543 |
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NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
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G |
CYSLTR1 |
cysteinyl leukotriene receptor 1 |
multiple interactions |
EXP ISO |
[CP 199330 binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; [CP 199331 binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; [CP 265298 binds to and results in decreased activity of CYSLTR1 protein] which results in decreased abundance of Calcium; [CP 288886 binds to and results in decreased activity of CYSLTR1 protein] which results in decreased abundance of Calcium; [Leukotriene C4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [Leukotriene D4 results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [Leukotriene E4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [pranlukast binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; [Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [zafirlukast binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; BAY u9773 inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; CYSLTR1 protein promotes the reaction [Leukotriene D4 results in increased abundance of Calcium]; montelukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; montelukast inhibits the reaction [[Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; pobilukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; pranlukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; verlukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; zafirlukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; zafirlukast inhibits the reaction [[Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; zafirlukast inhibits the reaction [CYSLTR1 protein promotes the reaction [Leukotriene D4 results in increased abundance of Calcium]] |
CTD |
PMID:8014876 PMID:9934474 PMID:10391245 PMID:10462554 PMID:10509933 PMID:11093801 PMID:11705452 PMID:12853847 PMID:15792791 PMID:15990778 PMID:18704935 PMID:20083671 More...
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NCBI chr X:78,271,468...78,327,611
Ensembl chr X:78,271,468...78,327,691
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G |
CYSLTR2 |
cysteinyl leukotriene receptor 2 |
multiple interactions |
EXP |
[Leukotriene C4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene C4 results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene D4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene D4 results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene E4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene E4 results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; BAY u9773 inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium] |
CTD |
PMID:10851239 PMID:11093801 |
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NCBI chr13:48,653,929...48,711,226
Ensembl chr13:48,653,711...48,711,226
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G |
DDR1 |
discoidin domain receptor tyrosine kinase 1 |
affects expression |
ISO |
Calcium affects the expression of DDR1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 6:30,880,970...30,900,156
Ensembl chr 6:30,876,421...30,900,156
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G |
DMD |
dystrophin |
increases abundance multiple interactions |
ISO |
DMD gene mutant form results in increased abundance of Calcium Nifedipine inhibits the reaction [DMD gene mutant form results in increased abundance of Calcium] |
CTD |
PMID:24349043 |
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NCBI chr X:31,119,222...33,339,388
Ensembl chr X:31,097,677...33,339,609
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G |
DNAJB11 |
DnaJ heat shock protein family (Hsp40) member B11 |
multiple interactions decreases transport |
EXP |
[DNAJB11 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [DNAJB11 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin; DNAJB11 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium] |
CTD |
PMID:26085089 |
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NCBI chr 3:186,570,720...186,585,793
Ensembl chr 3:186,567,403...186,585,800
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G |
DNAJC3 |
DnaJ heat shock protein family (Hsp40) member C3 |
multiple interactions decreases transport |
EXP |
[DNAJC3 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [DNAJC3 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin; DNAJC3 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium] |
CTD |
PMID:26085089 |
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NCBI chr13:95,677,139...95,794,988
Ensembl chr13:95,677,139...95,794,988
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G |
DRD1 |
dopamine receptor D1 |
multiple interactions |
ISO |
[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased activity of DRD1 protein] which results in increased abundance of Calcium |
CTD |
PMID:14622123 |
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NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
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G |
DRD2 |
dopamine receptor D2 |
multiple interactions |
EXP ISO |
[Norepinephrine binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium; [Quinpirole binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium; Sulpiride inhibits the reaction [[Norepinephrine binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium]; Sulpiride inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium] [DRD2 protein affects the abundance of Calcium] which results in decreased transport of Barium |
CTD |
PMID:8032591 PMID:11124974 |
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NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
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G |
DRD3 |
dopamine receptor D3 |
increases phosphorylation |
ISO |
Calcium results in increased phosphorylation of DRD3 protein |
CTD |
PMID:19217379 |
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NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
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G |
DUSP1 |
dual specificity phosphatase 1 |
multiple interactions |
ISO |
Calcium affects the reaction [Potassium Chloride results in increased expression of DUSP1 mRNA] |
CTD |
PMID:11577072 |
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NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195
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G |
EDN1 |
endothelin 1 |
increases abundance increases uptake multiple interactions affects transport affects localization |
ISO EXP |
EDN1 protein results in increased abundance of Calcium EDN1 protein results in increased uptake of Calcium EDN1 protein affects the localization of and affects the abundance of Calcium carvedilol inhibits the reaction [EDN1 protein results in increased import of and results in increased abundance of Calcium]; EDN1 protein affects the abundance of and affects the localization of Calcium; EDN1 protein results in increased import of and results in increased abundance of Calcium; Glucose affects the reaction [EDN1 protein affects the abundance of and affects the localization of Calcium]; Heparin inhibits the reaction [EDN1 protein results in increased abundance of Calcium] EDN1 protein affects the transport of Calcium EDN1 protein results in increased transport of and results in increased abundance of Calcium; Propofol inhibits the reaction [EDN1 protein affects the transport of Calcium] EDN1 protein affects the localization of Calcium |
CTD |
PMID:1443220 PMID:9138053 PMID:11425647 PMID:12628492 PMID:12821678 PMID:14711191 PMID:27226631 More...
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NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194
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G |
EDN2 |
endothelin 2 |
increases uptake multiple interactions |
ISO |
EDN2 protein results in increased uptake of Calcium EDN2 protein affects the localization of and affects the abundance of Calcium |
CTD |
PMID:11425647 |
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NCBI chr 1:41,478,775...41,484,683
Ensembl chr 1:41,478,775...41,484,683
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G |
EDN3 |
endothelin 3 |
multiple interactions increases uptake |
ISO |
EDN3 protein affects the localization of and affects the abundance of Calcium BQ 788 inhibits the reaction [EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium]]; EDN3 protein inhibits the reaction [APP protein results in increased uptake of Calcium]; EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium] EDN3 protein results in increased uptake of Calcium |
CTD |
PMID:11425647 PMID:12383957 PMID:15695168 |
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NCBI chr20:59,300,611...59,325,992
Ensembl chr20:59,300,443...59,325,992
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G |
EDNRA |
endothelin receptor type A |
affects activity |
ISO |
Calcium affects the activity of EDNRA protein |
CTD |
PMID:12628492 |
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NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954
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G |
EEF2 |
eukaryotic translation elongation factor 2 |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of EEF2 mRNA |
CTD |
PMID:15913539 |
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NCBI chr19:3,976,056...3,985,463
Ensembl chr19:3,976,056...3,985,463
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G |
EGF |
epidermal growth factor |
increases abundance multiple interactions affects expression increases transport |
EXP ISO |
EGF protein results in increased abundance of Calcium [Calcium co-treated with Calcitriol] affects the expression of EGF mRNA Calcium affects the expression of EGF mRNA EGF protein results in increased transport of Calcium [IGF2 protein co-treated with EGF protein] results in increased import of Calcium RTKI cpd inhibits the reaction [EGF protein results in increased abundance of Calcium] |
CTD |
PMID:2442157 PMID:11527950 PMID:15913539 PMID:24990931 |
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NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
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G |
EGFR |
epidermal growth factor receptor |
multiple interactions |
ISO |
Calcium affects the phosphorylation of and affects the expression of EGFR protein |
CTD |
PMID:8393775 |
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NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
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G |
EGR1 |
early growth response 1 |
multiple interactions |
EXP |
[[CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium] which results in increased expression of EGR1 mRNA; [Ionomycin results in increased abundance of Calcium] which results in increased expression of EGR1 protein |
CTD |
PMID:12517959 |
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NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
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G |
EIF2AK3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions |
EXP |
Calcium promotes the reaction [Diclofenac results in increased phosphorylation of EIF2AK3 protein] |
CTD |
PMID:26609140 |
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NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518
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G |
EIF4A2 |
eukaryotic translation initiation factor 4A2 |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of EIF4A2 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 3:186,783,577...186,789,897
Ensembl chr 3:186,783,205...186,789,897
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G |
EIF4EBP1 |
eukaryotic translation initiation factor 4E binding protein 1 |
multiple interactions |
ISO |
Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of EIF4EBP1 protein] |
CTD |
PMID:12935885 |
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NCBI chr 8:38,030,534...38,060,365
Ensembl chr 8:38,030,534...38,060,365
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G |
EPHX2 |
epoxide hydrolase 2 |
affects expression |
ISO |
Calcium affects the expression of EPHX2 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564
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G |
F2 |
coagulation factor II, thrombin |
increases abundance increases localization multiple interactions increases uptake |
EXP |
F2 protein results in increased abundance of Calcium F2 protein results in increased localization of Calcium 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [F2 protein results in increased localization of Calcium]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [F2 protein results in increased localization of Calcium]; Apigenin inhibits the reaction [F2 protein results in increased localization of Calcium]; arsenite inhibits the reaction [F2 protein results in increased abundance of Calcium]; Genistein inhibits the reaction [F2 protein results in increased localization of Calcium]; Nickel inhibits the reaction [F2 protein results in increased uptake of Calcium]; Quercetin inhibits the reaction [F2 protein results in increased localization of Calcium] |
CTD |
PMID:2125206 PMID:19814731 PMID:22244921 |
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NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
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G |
F2R |
coagulation factor II thrombin receptor |
multiple interactions |
ISO |
[Peptides results in increased activity of F2R protein] which results in increased abundance of Calcium |
CTD |
PMID:15086339 |
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NCBI chr 5:76,716,126...76,735,770
Ensembl chr 5:76,716,126...76,735,770
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G |
F2RL1 |
F2R like trypsin receptor 1 |
multiple interactions |
EXP |
F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]; PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]] |
CTD |
PMID:16793902 |
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NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315
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G |
F2RL3 |
F2R like thrombin or trypsin receptor 3 |
multiple interactions |
EXP ISO |
[alanyl-tyrosyl-prolyl-glycyl-lysyl-phenylalanine binds to and results in increased activity of F2RL3 protein] which results in increased uptake of Calcium F2RL3 protein affects the localization of and affects the transport of Calcium |
CTD |
PMID:16702038 PMID:17707436 |
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NCBI chr19:16,888,999...16,892,606
Ensembl chr19:16,888,999...16,892,606
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G |
F8 |
coagulation factor VIII |
multiple interactions |
EXP |
[Copper co-treated with Calcium] results in increased activity of [F8 protein alternative form binds to F8 protein alternative form]; Calcium results in increased activity of [F8 protein alternative form binds to F8 protein alternative form] |
CTD |
PMID:11513607 |
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NCBI chr X:154,835,792...155,022,723
Ensembl chr X:154,835,788...155,026,940
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G |
FASLG |
Fas ligand |
multiple interactions affects localization |
ISO |
bafilomycin A1 inhibits the reaction [FASL protein affects the localization of Calcium]; CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]; CD38 protein inhibits the reaction [CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]]; Ryanodine inhibits the reaction [FASL protein affects the localization of Calcium] |
CTD |
PMID:20200208 |
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NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
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G |
FGF1 |
fibroblast growth factor 1 |
increases expression |
ISO |
Calcium results in increased expression of FGF1 protein |
CTD |
PMID:15264218 |
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NCBI chr 5:142,592,178...142,698,070
Ensembl chr 5:142,592,178...142,698,070
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G |
FGF23 |
fibroblast growth factor 23 |
affects expression |
EXP |
Calcium affects the expression of FGF23 mRNA; Calcium affects the expression of FGF23 protein |
CTD |
PMID:15086938 PMID:16381997 |
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NCBI chr12:4,368,227...4,379,712
Ensembl chr12:4,368,227...4,379,712
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G |
FGF9 |
fibroblast growth factor 9 |
affects expression |
ISO |
Calcium affects the expression of FGF9 mRNA |
CTD |
PMID:15913539 |
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NCBI chr13:21,671,073...21,704,498
Ensembl chr13:21,671,073...21,704,498
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G |
FGFR1 |
fibroblast growth factor receptor 1 |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of FGFR1 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
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G |
FIS1 |
fission, mitochondrial 1 |
affects expression |
ISO |
Calcium affects the expression of FIS1 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316
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G |
FKBP1A |
FKBP prolyl isomerase 1A |
multiple interactions |
EXP |
FKBP1A protein inhibits the reaction [Calcium results in increased activity of RYR2 protein] |
CTD |
PMID:17872463 |
|
NCBI chr20:1,368,978...1,393,054
Ensembl chr20:1,368,977...1,393,164
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G |
FKBP1B |
FKBP prolyl isomerase 1B |
multiple interactions |
ISO |
FKBP1B gene mutant form inhibits the reaction [Acetylcholine affects the localization of and affects the abundance of Calcium]; Ryanodine inhibits the reaction [FKBP1B gene mutant form inhibits the reaction [Acetylcholine affects the localization of and affects the abundance of Calcium]] |
CTD |
PMID:17261647 |
|
NCBI chr 2:24,033,206...24,063,681
Ensembl chr 2:24,049,701...24,063,681
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G |
FURIN |
furin, paired basic amino acid cleaving enzyme |
affects expression |
ISO |
Calcium affects the expression of FURIN mRNA |
CTD |
PMID:15913539 |
|
NCBI chr15:90,868,588...90,883,457
Ensembl chr15:90,868,588...90,883,564
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G |
FXYD2 |
FXYD domain containing ion transport regulator 2 |
multiple interactions decreases activity |
EXP |
Calcium inhibits the reaction [FXYD2 protein results in increased transport of Deoxyglucose]; Calcium inhibits the reaction [FXYD2 protein results in increased transport of Inulin] Calcium results in decreased activity of FXYD2 protein |
CTD |
PMID:11533133 |
|
NCBI chr11:117,820,057...117,828,089
Ensembl chr11:117,800,844...117,828,698
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G |
G6PC1 |
glucose-6-phosphatase catalytic subunit 1 |
affects expression |
ISO |
Calcium affects the expression of G6PC1 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438
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G |
GABBR1 |
gamma-aminobutyric acid type B receptor subunit 1 |
multiple interactions affects expression |
EXP ISO |
Calcium promotes the reaction [3-aminopropylphosphinic acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]; Calcium promotes the reaction [CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]]; Calcium promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]] Calcium affects the expression of GABBR1 mRNA |
CTD |
PMID:15627515 PMID:15913539 |
|
NCBI chr 6:29,602,238...29,633,183
Ensembl chr 6:29,555,629...29,633,976
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G |
GABBR2 |
gamma-aminobutyric acid type B receptor subunit 2 |
multiple interactions |
EXP |
Calcium promotes the reaction [3-aminopropylphosphinic acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]; Calcium promotes the reaction [CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]]; Calcium promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]] |
CTD |
PMID:15627515 |
|
NCBI chr 9:98,288,109...98,708,935
Ensembl chr 9:98,288,109...98,708,935
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G |
GAST |
gastrin |
multiple interactions |
EXP |
Calcium promotes the reaction [Colforsin results in increased secretion of GAST protein]; Calcium promotes the reaction [Terbutaline results in increased secretion of GAST protein] |
CTD |
PMID:9277405 |
|
NCBI chr17:41,712,331...41,715,969
Ensembl chr17:41,712,331...41,715,969
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G |
GATA1 |
GATA binding protein 1 |
affects expression |
ISO |
Calcium affects the expression of GATA1 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr X:48,786,590...48,794,311
Ensembl chr X:48,786,540...48,794,311
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G |
GC |
GC vitamin D binding protein |
affects expression |
ISO |
Calcium affects the expression of GC mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 4:71,741,693...71,805,520
Ensembl chr 4:71,741,696...71,804,041
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G |
GCG |
glucagon |
multiple interactions |
ISO |
Calcium affects the reaction [Pyruvic Acid results in increased secretion of GCG protein] |
CTD |
PMID:15919803 |
|
NCBI chr 2:162,142,882...162,152,247
Ensembl chr 2:162,142,882...162,152,404
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G |
GCLC |
glutamate-cysteine ligase catalytic subunit |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of GCLC mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
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G |
GFAP |
glial fibrillary acidic protein |
multiple interactions |
ISO |
Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]; Calcium deficiency inhibits the reaction [Ethanol results in increased expression of GFAP protein] |
CTD |
PMID:17888892 PMID:21879721 |
|
NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937
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G |
GHR |
growth hormone receptor |
affects expression multiple interactions |
ISO |
Calcium affects the expression of GHR mRNA [Calcium co-treated with Calcitriol] affects the expression of GHR mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 5:42,423,439...42,721,878
Ensembl chr 5:42,423,439...42,721,878
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G |
GIPC3 |
GIPC PDZ domain containing family member 3 |
affects uptake |
ISO |
GIPC3 protein affects the uptake of Calcium |
CTD |
PMID:27462107 |
|
NCBI chr19:3,585,478...3,593,541
Ensembl chr19:3,585,478...3,593,541
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G |
GLRX3 |
glutaredoxin 3 |
affects response to substance |
ISO |
GLRX3 protein affects the susceptibility to Calcium |
CTD |
PMID:16809552 |
|
NCBI chr10:130,136,391...130,180,377
Ensembl chr10:130,136,391...130,184,521
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G |
GNAI2 |
G protein subunit alpha i2 |
affects expression |
ISO |
Calcium affects the expression of GNAI2 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 3:50,227,068...50,263,358
Ensembl chr 3:50,226,292...50,259,362
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G |
GNAS |
GNAS complex locus |
multiple interactions |
ISO |
[[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium; [[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium |
CTD |
PMID:23022524 |
|
NCBI chr20:58,839,748...58,911,192
Ensembl chr20:58,839,718...58,911,192
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G |
GPBAR1 |
G protein-coupled bile acid receptor 1 |
multiple interactions |
EXP ISO |
[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased abundance of Calcium [[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium; [[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium |
CTD |
PMID:23022524 |
|
NCBI chr 2:218,259,496...218,263,861
Ensembl chr 2:218,259,496...218,263,861
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G |
GRIA1 |
glutamate ionotropic receptor AMPA type subunit 1 |
multiple interactions |
ISO |
Calcium deficiency inhibits the reaction [Excitatory Amino Acid Agonists results in decreased phosphorylation of GRIA1 protein] |
CTD |
PMID:28404816 |
|
NCBI chr 5:153,489,615...153,813,869
Ensembl chr 5:153,489,615...153,813,869
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G |
GRIA2 |
glutamate ionotropic receptor AMPA type subunit 2 |
multiple interactions |
ISO |
Calcium promotes the reaction [PICK1 protein binds to GRIA2 protein] |
CTD |
PMID:28404816 |
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NCBI chr 4:157,220,120...157,366,075
Ensembl chr 4:157,204,182...157,387,146
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G |
GRM1 |
glutamate metabotropic receptor 1 |
multiple interactions |
ISO |
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]; [3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium; Flufenamic Acid inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]; GRM1 protein promotes the reaction [Propionates results in increased transport of Calcium]; Ruthenium Red inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium] |
CTD |
PMID:14622174 PMID:24582715 |
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NCBI chr 6:146,027,707...146,437,601
Ensembl chr 6:146,027,646...146,437,601
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G |
GSR |
glutathione-disulfide reductase |
multiple interactions |
ISO |
[Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in decreased activity of GSR protein]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in decreased activity of GSR protein]; [Carmustine results in decreased activity of GSR protein] which results in increased uptake of Calcium; Calcium affects the reaction [sodium arsenite results in decreased activity of GSR protein] |
CTD |
PMID:15321730 PMID:24184500 |
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NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
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G |
HCAR3 |
hydroxycarboxylic acid receptor 3 |
increases abundance multiple interactions |
EXP |
HCAR3 protein results in increased abundance of Calcium Pertussis Toxin affects the reaction [HCAR3 protein results in increased abundance of Calcium] |
CTD |
PMID:19237584 |
|
NCBI chr12:122,714,756...122,716,811
Ensembl chr12:122,714,756...122,716,811
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G |
HECTD4 |
HECT domain E3 ubiquitin protein ligase 4 |
multiple interactions |
EXP |
Calcium affects the reaction [HECTD4 gene SNP affects the abundance of Lead] |
CTD |
PMID:28212632 |
|
NCBI chr12:112,160,195...112,382,431
Ensembl chr12:112,160,188...112,382,439
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G |
HES1 |
hes family bHLH transcription factor 1 |
affects expression |
ISO |
Calcium affects the expression of HES1 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732
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G |
HGF |
hepatocyte growth factor |
increases abundance |
ISO |
HGF protein results in increased abundance of Calcium |
CTD |
PMID:10963052 |
|
NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438
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G |
HMGCS2 |
3-hydroxy-3-methylglutaryl-CoA synthase 2 |
affects expression |
ISO |
Calcium affects the expression of HMGCS2 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 1:119,747,996...119,768,932
Ensembl chr 1:119,748,002...119,768,905
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G |
HMOX1 |
heme oxygenase 1 |
multiple interactions |
EXP |
Calcium affects the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA] |
CTD |
PMID:21443188 |
|
NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
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G |
HNF4A |
hepatocyte nuclear factor 4 alpha |
affects expression |
ISO |
Calcium affects the expression of HNF4A mRNA |
CTD |
PMID:15913539 |
|
NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,699...44,432,845
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G |
HNRNPD |
heterogeneous nuclear ribonucleoprotein D |
multiple interactions |
ISO |
Calcium deficiency promotes the reaction [HNRNPD protein binds to PTH 3' UTR] |
CTD |
PMID:18583400 |
|
NCBI chr 4:82,352,498...82,373,991
Ensembl chr 4:82,352,498...82,374,503
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G |
HNRNPU |
heterogeneous nuclear ribonucleoprotein U |
affects expression |
ISO |
Calcium affects the expression of SP120 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 1:244,850,297...244,864,543
Ensembl chr 1:244,840,638...244,864,560
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G |
HOMER1 |
homer scaffold protein 1 |
multiple interactions |
ISO |
HOMER1 protein alternative form inhibits the reaction [Caffeine promotes the reaction [RYR2 protein results in increased secretion of Calcium]]; HOMER1 protein alternative form inhibits the reaction [Cyclic ADP-Ribose promotes the reaction [RYR2 protein results in increased secretion of Calcium]] |
CTD |
PMID:12887973 |
|
NCBI chr 5:79,372,636...79,514,134
Ensembl chr 5:79,372,636...79,514,134
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G |
HPCA |
hippocalcin |
decreases response to substance |
ISO |
HPCA protein results in decreased susceptibility to Calcium |
CTD |
PMID:12445469 |
|
NCBI chr 1:32,885,996...32,894,646
Ensembl chr 1:32,885,994...32,898,441
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G |
HRH1 |
histamine receptor H1 |
multiple interactions increases abundance |
EXP |
[6-((2-(4-imidazolyl)ethyl)amino)heptanoic acid 4-toluidide binds to and results in increased activity of HRH1 protein] which results in increased abundance of Calcium; [Histamine results in increased activity of HRH1 protein] which results in increased abundance of Calcium; [HRH1 protein binds to Histamine] which results in increased import of Calcium; [HRH1 protein binds to Lidocaine] which results in increased import of Calcium; [HRH1 protein binds to Procaine] which results in increased import of Calcium; [HRH1 protein binds to Tetracaine] which results in increased import of Calcium; fexofenadine inhibits the reaction [[Histamine binds to and results in increased activity of HRH1 protein] which results in increased abundance of Calcium]; HRH1 protein promotes the reaction [Histamine results in increased export of Calcium]; Triprolidine inhibits the reaction [[Histamine results in increased activity of HRH1 protein] which results in increased abundance of Calcium]; Triprolidine inhibits the reaction [HRH1 protein promotes the reaction [Histamine results in increased export of Calcium]] HRH1 protein results in increased abundance of Calcium |
CTD |
PMID:2419744 PMID:11238657 PMID:11527950 PMID:19443731 PMID:32061592 |
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NCBI chr 3:11,137,238...11,263,557
Ensembl chr 3:11,137,093...11,263,557
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G |
HRH3 |
histamine receptor H3 |
multiple interactions |
ISO |
[4-(1H-imidazol-4-ylmethyl)piperidine binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; [Histamine binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; [imetit binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; [Methylhistamines binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; clobenpropit inhibits the reaction [[Methylhistamines binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium] |
CTD |
PMID:12706455 |
|
NCBI chr20:62,214,960...62,220,278
Ensembl chr20:62,214,960...62,220,278
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G |
HRH4 |
histamine receptor H4 |
multiple interactions |
EXP |
1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine inhibits the reaction [[4-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium]; 1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine inhibits the reaction [[clobenpropit binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium]; [4-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [alpha-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [clobenpropit binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [Histamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [imetit binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [N-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium |
CTD |
PMID:11181941 PMID:17507084 |
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NCBI chr18:24,460,637...24,479,974
Ensembl chr18:24,460,637...24,479,961
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G |
HSD17B12 |
hydroxysteroid 17-beta dehydrogenase 12 |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of HSD17B12 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr11:43,556,721...43,856,615
Ensembl chr11:43,680,680...43,856,617
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G |
HSP90AA1 |
heat shock protein 90 alpha family class A member 1 |
multiple interactions |
ISO |
Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]] |
CTD |
PMID:23184943 |
|
NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions decreases transport |
EXP |
[DNAJB11 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [DNAJC3 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [HSPA5 protein binds to SEC61A1 protein] which results in decreased transport of Calcium; [HSPA5 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin |
CTD |
PMID:26085089 |
|
NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
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G |
HSPA9 |
heat shock protein family A (Hsp70) member 9 |
increases abundance |
ISO |
HSPA9 protein results in increased abundance of Calcium |
CTD |
PMID:34308505 |
|
NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,675
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G |
HTR1A |
5-hydroxytryptamine receptor 1A |
increases activity |
EXP |
Calcium results in increased activity of HTR1A protein |
CTD |
PMID:11356925 |
|
NCBI chr 5:63,957,874...63,962,445
Ensembl chr 5:63,957,874...63,962,507
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G |
HTR2A |
5-hydroxytryptamine receptor 2A |
multiple interactions |
ISO |
HTR2A protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium] |
CTD |
PMID:16901936 |
|
NCBI chr13:46,831,546...46,898,082
Ensembl chr13:46,831,546...46,897,076
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G |
HTR2B |
5-hydroxytryptamine receptor 2B |
multiple interactions |
ISO |
Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK1 protein]; Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:18758753 |
|
NCBI chr 2:231,108,230...231,125,042
Ensembl chr 2:231,108,230...231,125,042
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G |
HTR7 |
5-hydroxytryptamine receptor 7 |
multiple interactions |
ISO |
HTR7 protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium] |
CTD |
PMID:16901936 |
|
NCBI chr10:90,740,823...90,858,039
Ensembl chr10:90,740,823...90,858,039
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G |
IFNG |
interferon gamma |
multiple interactions |
ISO EXP |
KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]] [IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]; [TNF protein co-treated with IFNG protein] promotes the reaction [Diclofenac affects the abundance of Calcium]; Calcium promotes the reaction [[Diclofenac co-treated with IFNG protein] results in increased phosphorylation of STAT1 protein] |
CTD |
PMID:23747339 PMID:26609140 |
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NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
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G |
IFT88 |
intraflagellar transport 88 |
multiple interactions increases uptake |
ISO |
Gadolinium inhibits the reaction [IFT88 protein mutant form results in increased uptake of Calcium]; IFT88 protein affects the reaction [PKD2 protein results in increased uptake of Calcium] |
CTD |
PMID:16396941 |
|
NCBI chr13:20,567,157...20,691,444
Ensembl chr13:20,567,138...20,691,444
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G |
IGF1 |
insulin like growth factor 1 |
affects expression multiple interactions increases import |
ISO |
Calcium affects the expression of IGF1 mRNA Cobalt inhibits the reaction [IGF1 protein results in increased import of Calcium]; tetramethrin inhibits the reaction [IGF1 protein results in increased import of Calcium] |
CTD |
PMID:1550224 PMID:2460452 PMID:2539779 PMID:15913539 |
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NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744
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G |
IGF2 |
insulin like growth factor 2 |
multiple interactions increases import |
ISO |
[IGF2 protein co-treated with EGF protein] results in increased import of Calcium; Cobalt inhibits the reaction [IGF2 protein results in increased import of Calcium]; Lanthanum inhibits the reaction [IGF2 protein results in increased import of Calcium]; Pertussis Toxin inhibits the reaction [IGF2 protein results in increased import of Calcium]; tetramethrin inhibits the reaction [IGF2 protein results in increased import of Calcium] |
CTD |
PMID:2442157 PMID:2460452 PMID:2539779 |
|
NCBI chr11:2,129,117...2,149,566
Ensembl chr11:2,129,112...2,158,391
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G |
IGFBP2 |
insulin like growth factor binding protein 2 |
affects expression |
ISO |
Calcium affects the expression of IGFBP2 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 2:216,632,828...216,664,436
Ensembl chr 2:216,632,828...216,664,436
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G |
IGFBP5 |
insulin like growth factor binding protein 5 |
affects expression decreases degradation |
ISO |
Calcium affects the expression of IGFBP5 mRNA Calcium results in decreased degradation of IGFBP5 protein |
CTD |
PMID:8894652 PMID:15913539 |
|
NCBI chr 2:216,672,105...216,695,549
Ensembl chr 2:216,672,105...216,695,549
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G |
IL11 |
interleukin 11 |
multiple interactions increases abundance |
ISO |
Flurbiprofen inhibits the reaction [IL11 protein results in increased abundance of Calcium]; IL13 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium]; IL4 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium]; IL6ST protein promotes the reaction [IL11 protein results in increased abundance of Calcium]; Indomethacin inhibits the reaction [IL11 protein results in increased abundance of Calcium]; TNFRSF11B protein inhibits the reaction [IL11 protein results in increased abundance of Calcium] |
CTD |
PMID:12110441 |
|
NCBI chr19:55,364,382...55,370,463
Ensembl chr19:55,364,382...55,370,463
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G |
IL13 |
interleukin 13 |
multiple interactions |
ISO |
IL13 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium] |
CTD |
PMID:12110441 |
|
NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
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G |
IL1B |
interleukin 1 beta |
multiple interactions |
ISO EXP |
KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]] |
CTD |
PMID:23747339 |
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NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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G |
IL4 |
interleukin 4 |
multiple interactions |
ISO |
IL4 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium] |
CTD |
PMID:12110441 |
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NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
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G |
IL6 |
interleukin 6 |
multiple interactions increases expression |
EXP |
Calcimycin inhibits the reaction [Calcium promotes the reaction [Histamine results in increased expression of IL6 protein]]; Calcium promotes the reaction [Histamine results in increased expression of IL6 protein]; Edetic Acid inhibits the reaction [Calcium promotes the reaction [Histamine results in increased expression of IL6 protein]] Calcium results in increased expression of IL6 mRNA |
CTD |
PMID:11238657 PMID:20682585 |
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NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
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G |
IL6ST |
interleukin 6 cytokine family signal transducer |
multiple interactions |
ISO |
IL6ST protein promotes the reaction [IL11 protein results in increased abundance of Calcium] |
CTD |
PMID:12110441 |
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NCBI chr 5:55,935,095...55,994,963
Ensembl chr 5:55,935,095...55,995,022
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G |
ILF3 |
interleukin enhancer binding factor 3 |
multiple interactions |
EXP |
Calcium affects the reaction [Vanadates results in increased activity of ILF3 protein] |
CTD |
PMID:10623810 |
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NCBI chr19:10,654,346...10,692,400
Ensembl chr19:10,654,304...10,692,400
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G |
INS-IGF2 |
INS-IGF2 readthrough |
multiple interactions |
ISO |
Calcium deficiency inhibits the reaction [[Glucose co-treated with INS1 protein] results in increased secretion of LEP protein]; Calcium deficiency inhibits the reaction [INS1 protein results in increased activity of SLC2A1 protein]; Chromium affects the reaction [INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; chromium tripicolinate affects the reaction [INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; INS1 protein affects the reaction [Chromium affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; INS1 protein affects the reaction [chromium tripicolinate affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]] |
CTD |
PMID:9446840 PMID:10780946 PMID:10970766 |
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NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209
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G |
IQGAP1 |
IQ motif containing GTPase activating protein 1 |
multiple interactions |
ISO |
Calcium promotes the reaction [PAFAH1B1 protein binds to IQGAP1 protein binds to CDC42 protein] |
CTD |
PMID:16369480 |
|
NCBI chr15:90,388,242...90,502,239
Ensembl chr15:90,388,242...90,502,239
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G |
ITGA2 |
integrin subunit alpha 2 |
multiple interactions |
ISO |
ITGA2 protein promotes the reaction [[Dinoprostone co-treated with Serotonin] results in increased import of Calcium]; TRPV4 protein promotes the reaction [ITGA2 protein promotes the reaction [[Dinoprostone co-treated with Serotonin] results in increased import of Calcium]] |
CTD |
PMID:18234883 |
|
NCBI chr 5:52,989,352...53,094,779
Ensembl chr 5:52,989,340...53,094,779
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G |
ITGB1BP2 |
integrin subunit beta 1 binding protein 2 |
multiple interactions |
EXP ISO |
Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to SUGT1 protein]] Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]] |
CTD |
PMID:23184943 |
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NCBI chr X:71,301,750...71,305,371
Ensembl chr X:71,301,750...71,305,371
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G |
ITIH1 |
inter-alpha-trypsin inhibitor heavy chain 1 |
multiple interactions |
EXP |
Calcium promotes the reaction [ITIH1 protein binds to TNFAIP6 protein] |
CTD |
PMID:16768462 |
|
NCBI chr 3:52,777,599...52,792,068
Ensembl chr 3:52,777,595...52,792,068
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G |
ITIH2 |
inter-alpha-trypsin inhibitor heavy chain 2 |
multiple interactions |
EXP |
Calcium promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] |
CTD |
PMID:16768462 |
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NCBI chr10:7,703,316...7,749,520
Ensembl chr10:7,703,316...7,749,520
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G |
ITPR1 |
inositol 1,4,5-trisphosphate receptor type 1 |
multiple interactions |
EXP |
ITPR1 protein promotes the reaction [Acetaldehyde metabolite results in increased abundance of Calcium]; ITPR1 protein promotes the reaction [Ethanol metabolite results in increased abundance of Calcium] |
CTD |
PMID:17241155 |
|
NCBI chr 3:4,493,348...4,847,506
Ensembl chr 3:4,493,345...4,847,506
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G |
ITPR2 |
inositol 1,4,5-trisphosphate receptor type 2 |
multiple interactions |
ISO |
2-aminoethoxydiphenyl borate inhibits the reaction [[adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium]; [adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium; xestospongin C inhibits the reaction [[adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium] |
CTD |
PMID:15201137 |
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NCBI chr12:26,335,352...26,833,194
Ensembl chr12:26,335,352...26,833,194
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G |
ITPR3 |
inositol 1,4,5-trisphosphate receptor type 3 |
affects expression |
ISO |
Calcium affects the expression of ITPR3 protein |
CTD |
PMID:10963052 |
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NCBI chr 6:33,621,322...33,696,562
Ensembl chr 6:33,620,365...33,696,574
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G |
IVL |
involucrin |
increases expression multiple interactions |
EXP |
Calcium results in increased expression of IVL mRNA NPS R-467 promotes the reaction [Calcium results in increased expression of IVL mRNA] |
CTD |
PMID:10469331 |
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NCBI chr 1:152,908,546...152,911,886
Ensembl chr 1:152,908,546...152,911,886
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G |
JAK2 |
Janus kinase 2 |
multiple interactions |
ISO |
JAK2 protein promotes the reaction [LEP protein results in increased transport of Calcium] |
CTD |
PMID:20107083 |
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NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948
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G |
KCNE1 |
potassium voltage-gated channel subfamily E regulatory subunit 1 |
increases activity multiple interactions |
ISO |
Calcium results in increased activity of KCNE1 protein W 7 inhibits the reaction [Calcium results in increased activity of KCNE1 protein] |
CTD |
PMID:1655403 |
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NCBI chr21:34,446,688...34,512,210
Ensembl chr21:34,446,688...34,512,214
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G |
KCNH2 |
potassium voltage-gated channel subfamily H member 2 |
multiple interactions |
ISO |
Nimodipine inhibits the reaction [KCNH2 protein affects the abundance of Calcium] |
CTD |
PMID:11040061 |
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NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321
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G |
KCNJ11 |
potassium inwardly rectifying channel subfamily J member 11 |
multiple interactions affects abundance |
ISO |
Dantrolene inhibits the reaction [KCNJ11 protein mutant form results in increased abundance of Calcium]; KCNJ11 protein affects the reaction [[Manganese co-treated with Dobutamine] results in increased abundance of Calcium]; W 7 inhibits the reaction [KCNJ11 protein mutant form results in increased abundance of Calcium] KCNJ11 protein affects the abundance of Calcium |
CTD |
PMID:17189350 |
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NCBI chr11:17,385,248...17,389,346
Ensembl chr11:17,365,172...17,389,331
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G |
KCNMA1 |
potassium calcium-activated channel subfamily M alpha 1 |
multiple interactions increases response to substance |
EXP ISO |
[KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium; Lithocholic Acid promotes the reaction [[KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium] KCNMA1 mRNA alternative form results in increased susceptibility to Calcium |
CTD |
PMID:22123969 PMID:28090300 |
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NCBI chr10:76,869,602...77,637,808
Ensembl chr10:76,869,601...77,638,369
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G |
KCNMB1 |
potassium calcium-activated channel subfamily M regulatory beta subunit 1 |
multiple interactions |
EXP |
[KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium; Lithocholic Acid promotes the reaction [[KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium] |
CTD |
PMID:22123969 |
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NCBI chr 5:170,374,671...170,389,367
Ensembl chr 5:170,374,671...170,389,634
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G |
KCNN2 |
potassium calcium-activated channel subfamily N member 2 |
increases activity multiple interactions |
EXP |
Calcium results in increased activity of KCNN2 protein cyclohexyl-(2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl)amine promotes the reaction [Calcium results in increased activity of KCNN2 protein] |
CTD |
PMID:17486140 |
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NCBI chr 5:114,055,978...114,496,496
Ensembl chr 5:114,055,926...114,496,500
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G |
KCNN3 |
potassium calcium-activated channel subfamily N member 3 |
multiple interactions increases activity |
EXP |
6,7-dichloro-1H-indole-2,3-dione 3-oxime promotes the reaction [Calcium results in increased activity of KCNN3 protein]; cyclohexyl-(2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl)amine promotes the reaction [Calcium results in increased activity of KCNN3 protein] |
CTD |
PMID:17486140 |
|
NCBI chr 1:154,697,455...154,870,281
Ensembl chr 1:154,697,455...154,870,281
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G |
KCNN4 |
potassium calcium-activated channel subfamily N member 4 |
affects abundance multiple interactions |
EXP |
KCNN4 protein affects the abundance of Calcium KCNN4 protein affects the reaction [Calcium results in increased transport of Potassium] |
CTD |
PMID:11826162 PMID:14985237 |
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NCBI chr19:43,766,533...43,780,973
Ensembl chr19:43,766,533...43,780,976
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G |
KDR |
kinase insert domain receptor |
multiple interactions |
EXP ISO |
[VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium; TRPC6 protein promotes the reaction [[VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium] Calcium promotes the reaction [Corticosterone results in decreased expression of KDR protein] |
CTD |
PMID:14551041 PMID:21647420 |
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NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595
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G |
KHSRP |
KH-type splicing regulatory protein |
multiple interactions |
ISO |
Calcium deficiency inhibits the reaction [KHSRP protein binds to PTH 3' UTR] |
CTD |
PMID:18583400 |
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NCBI chr19:6,413,102...6,424,811
Ensembl chr19:6,413,102...6,424,811
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G |
KISS1 |
KiSS-1 metastasis suppressor |
multiple interactions |
ISO |
2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; [KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium; Flufenamic Acid inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin promotes the reaction [2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]] |
CTD |
PMID:18948403 |
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NCBI chr 1:204,190,341...204,196,491
Ensembl chr 1:204,190,341...204,196,491
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G |
KISS1R |
KISS1 receptor |
multiple interactions |
ISO |
2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; [KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium; Flufenamic Acid inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin promotes the reaction [2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]] |
CTD |
PMID:18948403 |
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NCBI chr19:917,333...921,005
Ensembl chr19:917,287...921,005
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G |
KL |
klotho |
affects abundance multiple interactions |
ISO |
KL protein affects the abundance of Calcium KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]] |
CTD |
PMID:11796525 PMID:23747339 |
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NCBI chr13:33,016,243...33,066,143
Ensembl chr13:33,016,423...33,066,143
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G |
KLK1 |
kallikrein 1 |
decreases activity |
EXP |
Calcium results in decreased activity of KLK1 protein |
CTD |
PMID:15558947 |
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NCBI chr19:50,819,146...50,823,787
Ensembl chr19:50,819,146...50,823,787
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G |
KLK8 |
kallikrein related peptidase 8 |
increases activity |
EXP |
Calcium results in increased activity of KLK8 protein |
CTD |
PMID:16800733 |
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NCBI chr19:50,996,008...51,001,604
Ensembl chr19:50,996,007...51,002,711
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G |
KNG1 |
kininogen 1 |
multiple interactions increases abundance affects abundance |
EXP ISO |
BDKRB2 protein affects the reaction [KNG1 protein affects the abundance of Calcium] [KNG1 protein alternative form co-treated with Calcium] results in increased secretion of CALCA protein; Calcium affects the reaction [KNG1 protein results in increased secretion of Excitatory Amino Acid Agents] B 4162 inhibits the reaction [pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]]; BDKRB2 protein affects the reaction [pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]]; CALR protein promotes the reaction [KNG1 protein modified form results in increased abundance of Calcium]; KNG1 protein affects the transport of and affects the localization of Calcium; pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium] KNG1 protein results in increased abundance of Calcium |
CTD |
PMID:7961812 PMID:8592139 PMID:10535458 PMID:12582005 PMID:16473424 PMID:17666428 PMID:18054572 More...
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NCBI chr 3:186,717,359...186,744,410
Ensembl chr 3:186,717,348...186,744,410
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G |
KRT1 |
keratin 1 |
multiple interactions increases expression |
ISO EXP |
12-Hydroxy-5,8,10,14-eicosatetraenoic Acid inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; 15-hydroxy-5,8,11,13-eicosatetraenoic acid inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; 8-hydroxyeicosatetraenoic acid promotes the reaction [Calcium results in increased expression of KRT1 mRNA]; Masoprocol inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; morin inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; Quercetin inhibits the reaction [Calcium results in increased expression of KRT1 mRNA] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of KRT1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of KRT1 protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; SB 203580 inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; SB 203580 inhibits the reaction [Calcium results in increased expression of KRT1 protein]; WNT5A protein promotes the reaction [Calcium results in increased expression of KRT1 mRNA]; WNT5A protein promotes the reaction [Calcium results in increased expression of KRT1 protein] Calcium results in increased expression of KRT1 mRNA; Calcium results in increased expression of KRT1 protein |
CTD |
PMID:12069687 PMID:21524694 PMID:24658506 |
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NCBI chr12:52,674,736...52,680,407
Ensembl chr12:52,674,736...52,680,407
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G |
LEP |
leptin |
affects abundance multiple interactions affects secretion increases transport affects expression decreases abundance |
ISO |
LEP protein affects the abundance of Calcium Calcium deficiency inhibits the reaction [[Glucose co-treated with INS1 protein] results in increased secretion of LEP protein] Calcium deficiency affects the secretion of LEP protein LEP protein results in increased transport of Calcium 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [LEP protein results in increased transport of Calcium]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [LEP protein results in increased transport of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [LEP protein results in increased transport of Calcium]; acetovanillone inhibits the reaction [LEP protein affects the abundance of Calcium]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [LEP protein results in increased transport of Calcium]; BQ 788 inhibits the reaction [LEP protein affects the abundance of Calcium]; Calcium promotes the reaction [LEP protein results in increased transport of Calcium]; cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [LEP protein affects the abundance of Calcium]; edelfosine inhibits the reaction [LEP protein results in increased transport of Calcium]; Flufenamic Acid inhibits the reaction [LEP protein results in increased transport of Calcium]; JAK2 protein promotes the reaction [LEP protein results in increased transport of Calcium]; Lanthanum promotes the reaction [LEP protein results in increased transport of Calcium]; LEP protein promotes the reaction [TRPC1 protein results in increased transport of Calcium]; LEP protein promotes the reaction [TRPC4 protein results in increased transport of Calcium]; LEP protein promotes the reaction [TRPC5 protein results in increased transport of Calcium]; wortmannin inhibits the reaction [LEP protein results in increased transport of Calcium] Calcium affects the expression of LEP mRNA LEP protein results in decreased abundance of Calcium |
CTD |
PMID:10780946 PMID:14657008 PMID:15913539 PMID:16380530 PMID:20107083 |
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NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629
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G |
LEPR |
leptin receptor |
affects expression |
ISO |
Calcium affects the expression of LEPR mRNA |
CTD |
PMID:15913539 |
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NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559
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G |
LIF |
LIF interleukin 6 family cytokine |
increases abundance |
ISO |
LIF protein results in increased abundance of Calcium |
CTD |
PMID:11073891 |
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NCBI chr22:30,240,453...30,246,759
Ensembl chr22:30,240,453...30,246,759
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G |
LORICRIN |
loricrin cornified envelope precursor protein |
increases expression multiple interactions |
EXP |
Calcium results in increased expression of LORICRIN mRNA; Calcium results in increased expression of LORICRIN protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of LORICRIN mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of LORICRIN protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; SB 203580 inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; SB 203580 inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; WNT5A protein promotes the reaction [Calcium results in increased expression of LORICRIN mRNA]; WNT5A protein promotes the reaction [Calcium results in increased expression of LORICRIN protein] |
CTD |
PMID:21524694 PMID:24658506 |
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NCBI chr 1:153,259,687...153,262,124
Ensembl chr 1:153,259,687...153,262,124
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G |
LYPLA1 |
lysophospholipase 1 |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of LYPLA1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 8:54,046,367...54,101,947
Ensembl chr 8:54,046,367...54,102,017
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G |
MAP2K1 |
mitogen-activated protein kinase kinase 1 |
multiple interactions |
ISO |
[Sumatriptan results in increased abundance of Calcium] inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA]; Calcium inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA] |
CTD |
PMID:12574409 |
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NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656
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G |
MAP2K2 |
mitogen-activated protein kinase kinase 2 |
affects expression |
ISO |
Calcium affects the expression of MAP2K2 mRNA |
CTD |
PMID:15913539 |
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NCBI chr19:4,090,321...4,124,122
Ensembl chr19:4,090,321...4,124,122
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G |
MAPK1 |
mitogen-activated protein kinase 1 |
increases phosphorylation multiple interactions |
EXP ISO |
Calcium results in increased phosphorylation of MAPK1 protein Calcium promotes the reaction [Diclofenac results in increased phosphorylation of MAPK1 protein] Calcium affects the reaction [Ptychodiscus brevis T2 toxin affects the phosphorylation of MAPK1 protein]; Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK1 protein] Calcium deficiency inhibits the reaction [Carbachol results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
CTD |
PMID:10660688 PMID:15086530 PMID:16877402 PMID:17537980 PMID:18758753 PMID:19782052 PMID:26609140 More...
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NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
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G |
MAPK14 |
mitogen-activated protein kinase 14 |
affects expression |
ISO |
Calcium affects the expression of MAPK14 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,782...36,111,236
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G |
MAPK3 |
mitogen-activated protein kinase 3 |
increases phosphorylation multiple interactions |
EXP ISO |
Calcium results in increased phosphorylation of MAPK3 protein Calcium promotes the reaction [Diclofenac results in increased phosphorylation of MAPK3 protein] Calcium deficiency inhibits the reaction [Carbachol results in increased phosphorylation of and results in increased activity of MAPK3 protein] Calcium affects the reaction [Ptychodiscus brevis T2 toxin affects the phosphorylation of MAPK3 protein]; Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]; Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:10660688 PMID:15086530 PMID:16877402 PMID:17537980 PMID:18758753 PMID:19782052 PMID:26609140 More...
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NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
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G |
MAPK4 |
mitogen-activated protein kinase 4 |
affects expression |
ISO |
Calcium affects the expression of MAPK4 mRNA |
CTD |
PMID:15913539 |
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NCBI chr18:50,559,612...50,731,826
Ensembl chr18:50,560,087...50,731,826
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G |
MARCO |
macrophage receptor with collagenous structure |
multiple interactions |
EXP |
Calcium promotes the reaction [titanium dioxide binds to MARCO protein] |
CTD |
PMID:18836211 |
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NCBI chr 2:118,942,194...118,994,660
Ensembl chr 2:118,942,194...118,994,660
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G |
MCOLN1 |
mucolipin TRP cation channel 1 |
multiple interactions |
EXP |
[NAADP results in increased activity of MCOLN1 protein] which affects the localization of Calcium |
CTD |
PMID:21613607 |
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NCBI chr19:7,522,624...7,534,009
Ensembl chr19:7,522,624...7,534,009
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G |
MCU |
mitochondrial calcium uniporter |
affects localization |
ISO |
MCU protein affects the localization of Calcium |
CTD |
PMID:22829870 |
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NCBI chr10:72,692,143...72,887,694
Ensembl chr10:72,692,143...72,887,694
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G |
MGP |
matrix Gla protein |
multiple interactions affects expression affects binding |
EXP ISO |
[Calcium binds to MGP protein] which binds to and results in decreased activity of BMP4 protein; [Edetic Acid inhibits the reaction [Calcium binds to MGP protein]] inhibits the reaction [MGP protein binds to BMP4 protein]; Edetic Acid inhibits the reaction [Calcium binds to MGP protein] Calcium affects the expression of MGP mRNA |
CTD |
PMID:15913539 PMID:18369157 |
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NCBI chr12:14,880,864...14,885,854
Ensembl chr12:14,880,864...14,885,857
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G |
MMP1 |
matrix metallopeptidase 1 |
affects expression |
EXP |
Calcium affects the expression of MMP1 mRNA; Calcium affects the expression of MMP1 protein |
CTD |
PMID:17508023 |
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NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160
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G |
MTOR |
mechanistic target of rapamycin kinase |
multiple interactions |
ISO |
Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of MTOR protein] |
CTD |
PMID:12935885 |
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NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556
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G |
MYBPC3 |
myosin binding protein C3 |
multiple interactions increases response to substance |
ISO |
epigallocatechin gallate inhibits the reaction [MYBPC3 gene mutant form results in increased susceptibility to Calcium] |
CTD |
PMID:27994558 |
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NCBI chr11:47,331,406...47,352,702
Ensembl chr11:47,331,406...47,352,702
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G |
MYH7 |
myosin heavy chain 7 |
increases transport |
EXP |
MYH7 gene mutant form results in increased transport of Calcium |
CTD |
PMID:29741611 |
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NCBI chr14:23,412,740...23,435,660
Ensembl chr14:23,412,740...23,435,660
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G |
MYL2 |
myosin light chain 2 |
multiple interactions |
EXP |
Calcium affects the reaction [MYL2 gene SNP affects the abundance of Lead] |
CTD |
PMID:28212632 |
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NCBI chr12:110,910,845...110,921,449
Ensembl chr12:110,910,819...110,921,443
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G |
MYL3 |
myosin light chain 3 |
affects expression |
ISO |
Calcium affects the expression of MYL3 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 3:46,857,872...46,882,182
Ensembl chr 3:46,835,111...46,882,178
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G |
MYL9 |
myosin light chain 9 |
multiple interactions affects phosphorylation decreases phosphorylation |
ISO |
[[Calcium results in increased activity of MYLK protein] which results in increased phosphorylation of MYL9 protein] which results in decreased secretion of REN protein; [CACNA1D protein results in increased uptake of Calcium] which results in increased phosphorylation of MYL9 protein; [Escin affects the susceptibility to Calcium] which results in increased phosphorylation of MYL9 protein; Glycodeoxycholic Acid inhibits the reaction [[Escin affects the susceptibility to Calcium] which results in increased phosphorylation of MYL9 protein]; Y 27632 inhibits the reaction [[Escin affects the susceptibility to Calcium] which results in increased phosphorylation of MYL9 protein] Calcium affects the phosphorylation of MYL9 protein Calcium deficiency results in decreased phosphorylation of MYL9 protein |
CTD |
PMID:7503253 PMID:9618396 PMID:17272349 PMID:29660437 |
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NCBI chr20:36,541,519...36,551,447
Ensembl chr20:36,541,497...36,551,447
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G |
MYLK |
myosin light chain kinase |
increases activity multiple interactions |
EXP ISO |
Calcium deficiency results in increased activity of MYLK protein; Calcium results in increased activity of MYLK protein [[Calcium results in increased activity of MYLK protein] which results in increased phosphorylation of MYL9 protein] which results in decreased secretion of REN protein ML 7 inhibits the reaction [Calcium deficiency results in increased activity of MYLK protein] |
CTD |
PMID:9618396 PMID:10640419 PMID:11054866 |
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NCBI chr 3:123,610,049...123,884,332
Ensembl chr 3:123,610,049...123,884,332
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G |
MYO1B |
myosin IB |
increases activity |
ISO |
Calcium deficiency results in increased activity of MYO1B protein |
CTD |
PMID:10419463 |
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NCBI chr 2:191,245,404...191,425,386
Ensembl chr 2:191,245,185...191,425,389
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G |
MYO5A |
myosin VA |
affects activity |
ISO |
Calcium affects the activity of MYO5A protein |
CTD |
PMID:10660602 |
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NCBI chr15:52,307,283...52,529,050
Ensembl chr15:52,307,281...52,529,132
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G |
NAIP |
NLR family apoptosis inhibitory protein |
decreases response to substance |
ISO |
NAIP protein results in decreased susceptibility to Calcium |
CTD |
PMID:12445469 |
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NCBI chr 5:70,968,166...71,025,339
Ensembl chr 5:70,968,166...71,025,339
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G |
NCF1 |
neutrophil cytosolic factor 1 |
affects abundance |
ISO |
NCF1 protein affects the abundance of Calcium |
CTD |
PMID:16280459 |
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NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315
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G |
NDUFS1 |
NADH:ubiquinone oxidoreductase core subunit S1 |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of NDUFS1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 2:206,114,817...206,159,444
Ensembl chr 2:206,114,817...206,159,509
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G |
NEDD4 |
NEDD4 E3 ubiquitin protein ligase |
affects expression |
ISO |
Calcium affects the expression of NEDD4 mRNA |
CTD |
PMID:15913539 |
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NCBI chr15:55,826,917...55,993,612
Ensembl chr15:55,826,922...55,993,660
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G |
NEDD4L |
NEDD4 like E3 ubiquitin protein ligase |
multiple interactions |
ISO |
[NEDD4L gene mutant form results in increased susceptibility to Sodium, Dietary] which results in increased abundance of Calcium; Thiazides inhibits the reaction [[NEDD4L gene mutant form results in increased susceptibility to Sodium, Dietary] which results in increased abundance of Calcium] |
CTD |
PMID:23348737 |
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NCBI chr18:58,044,226...58,401,540
Ensembl chr18:58,044,226...58,401,540
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G |
NEFL |
neurofilament light chain |
multiple interactions |
ISO |
Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of NEFL protein]; calpeptin inhibits the reaction [Calcium results in increased degradation of NEFL protein]; Indomethacin inhibits the reaction [Calcium results in increased degradation of NEFL protein] |
CTD |
PMID:11071371 PMID:21879721 |
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NCBI chr 8:24,950,955...24,956,612
Ensembl chr 8:24,950,955...24,956,721
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G |
NEFM |
neurofilament medium chain |
multiple interactions |
ISO |
Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of NEFM protein] |
CTD |
PMID:21879721 |
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NCBI chr 8:24,913,761...24,919,093
Ensembl chr 8:24,913,758...24,919,098
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G |
NEK9 |
NIMA related kinase 9 |
affects expression |
ISO |
Calcium affects the expression of NEK9 mRNA |
CTD |
PMID:15913539 |
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NCBI chr14:75,079,353...75,127,202
Ensembl chr14:75,079,353...75,127,344
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G |
NF1 |
neurofibromin 1 |
decreases transport |
ISO |
NF1 protein results in decreased transport of Calcium |
CTD |
PMID:21949590 |
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NCBI chr17:31,094,927...31,377,677
Ensembl chr17:31,094,927...31,382,116
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G |
NFATC2 |
nuclear factor of activated T cells 2 |
multiple interactions |
ISO |
4-methyl-4'-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)-1,2,3-thiadiazole-5-carboxanilide inhibits the reaction [[Muscarine co-treated with Calcium] affects the localization of NFATC2 protein]; 4-methyl-4'-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)-1,2,3-thiadiazole-5-carboxanilide inhibits the reaction [[Thapsigargin co-treated with Calcium] affects the localization of NFATC2 protein]; [Muscarine co-treated with Calcium] affects the localization of NFATC2 protein; [Thapsigargin co-treated with Calcium] affects the localization of NFATC2 protein |
CTD |
PMID:24990931 |
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NCBI chr20:51,386,963...51,562,839
Ensembl chr20:51,386,957...51,562,831
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G |
NFE2L2 |
NFE2 like bZIP transcription factor 2 |
increases abundance |
ISO |
NFE2L2 gene mutant form results in increased abundance of Calcium |
CTD |
PMID:29618784 |
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NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
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G |
NFKBIA |
NFKB inhibitor alpha |
affects expression multiple interactions |
ISO EXP |
Calcium affects the expression of NFKBIA mRNA Calcium affects the reaction [Morphine inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]] |
CTD |
PMID:15913539 PMID:24068670 |
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NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
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G |
NGB |
neuroglobin |
affects transport |
EXP |
NGB protein affects the transport of Calcium |
CTD |
PMID:19154338 |
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NCBI chr14:77,265,483...77,271,206
Ensembl chr14:77,265,483...77,271,206
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G |
NGF |
nerve growth factor |
multiple interactions increases uptake |
ISO |
[NGF protein co-treated with 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester] results in increased uptake of Calcium; [NGF protein co-treated with Adenosine Triphosphate] results in increased uptake of Calcium; cadmium acetate inhibits the reaction [NGF protein results in increased uptake of Calcium]; Cadmium inhibits the reaction [NGF protein results in increased uptake of Calcium]; calmidazolium inhibits the reaction [NGF protein results in increased uptake of Calcium]; Fluphenazine inhibits the reaction [NGF protein results in increased uptake of Calcium]; Nifedipine inhibits the reaction [NGF protein results in increased uptake of Calcium]; Okadaic Acid promotes the reaction [NGF protein results in increased uptake of Calcium]; Staurosporine inhibits the reaction [NGF protein results in increased uptake of Calcium] |
CTD |
PMID:1374475 |
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NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770
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G |
NHERF4 |
NHERF family PDZ scaffold protein 4 |
multiple interactions |
ISO |
[[USP2 gene mutant form results in increased expression of NHERF4 protein] which results in increased activity of TRPV6 protein] which results in increased uptake of Calcium |
CTD |
PMID:26756164 |
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NCBI chr11:119,185,475...119,190,213
Ensembl chr11:119,185,457...119,190,223
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G |
NOA1 |
nitric oxide associated 1 |
multiple interactions |
ISO |
[Tamoxifen results in increased abundance of Calcium] which results in increased activity of NOA1 protein |
CTD |
PMID:17283165 |
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NCBI chr 4:56,963,350...56,977,606
Ensembl chr 4:56,963,350...56,977,606
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G |
NOS1 |
nitric oxide synthase 1 |
multiple interactions |
ISO |
[Calcium binds to CALM1 protein] promotes the reaction [NOS1 protein results in increased chemical synthesis of Nitric Oxide]; [Calcium binds to CALM1 protein] which binds to and affects the folding of and results in increased activity of NOS1 protein |
CTD |
PMID:17098364 |
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NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
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G |
NOS3 |
nitric oxide synthase 3 |
affects response to substance increases activity multiple interactions |
ISO EXP |
NOS3 protein affects the susceptibility to Calcium Calcium results in increased activity of NOS3 protein Calcium affects the reaction [Polycyclic Aromatic Hydrocarbons results in increased expression of and results in increased activity of NOS3 protein]; Calcium deficiency inhibits the reaction [Digitoxin results in increased activity of NOS3 protein]; Calcium deficiency inhibits the reaction [ginsenoside Re results in increased phosphorylation of NOS3 protein] |
CTD |
PMID:15183461 PMID:17403420 PMID:17490654 PMID:19380615 PMID:19446813 PMID:22244921 More...
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NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
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G |
NOX1 |
NADPH oxidase 1 |
multiple interactions |
ISO |
1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid inhibits the reaction [NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]]; NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]] |
CTD |
PMID:24912985 |
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NCBI chr X:100,843,324...100,874,359
Ensembl chr X:100,843,324...100,874,359
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G |
NPPC |
natriuretic peptide C |
increases uptake multiple interactions |
ISO |
NPPC protein results in increased uptake of Calcium Ammonia inhibits the reaction [NPPC protein results in increased uptake of Calcium]; Nimodipine inhibits the reaction [NPPC protein results in increased uptake of Calcium] |
CTD |
PMID:18222015 |
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NCBI chr 2:231,921,809...231,926,396
Ensembl chr 2:231,921,809...231,926,396
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G |
NPR1 |
natriuretic peptide receptor 1 |
affects expression |
ISO |
Calcium affects the expression of NPR1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 1:153,678,688...153,693,992
Ensembl chr 1:153,678,688...153,693,992
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G |
NR0B2 |
nuclear receptor subfamily 0 group B member 2 |
affects expression |
ISO |
Calcium affects the expression of NR0B2 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 1:26,911,489...26,913,975
Ensembl chr 1:26,911,489...26,913,975
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G |
NR1D2 |
nuclear receptor subfamily 1 group D member 2 |
affects expression |
ISO |
Calcium affects the expression of NR1D2 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 3:23,945,286...23,980,617
Ensembl chr 3:23,945,286...23,980,617
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G |
NRXN1 |
neurexin 1 |
multiple interactions |
ISO |
Calcium affects the reaction [alpha-latrotoxin binds to NRXN1 protein]; Calcium affects the reaction [black widow spider venom binds to NRXN1 protein] |
CTD |
PMID:9430716 |
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NCBI chr 2:49,918,503...51,032,132
Ensembl chr 2:49,918,503...51,225,575
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G |
NUCB2 |
nucleobindin 2 |
multiple interactions |
ISO |
KT 5720 inhibits the reaction [NUCB2 protein results in increased import of Calcium] |
CTD |
PMID:17627999 |
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NCBI chr11:17,276,739...17,349,980
Ensembl chr11:17,208,153...17,349,980
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G |
OCLN |
occludin |
multiple interactions |
EXP |
Calcium deficiency inhibits the reaction [TJP1 protein binds to OCLN protein] |
CTD |
PMID:11054866 |
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NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104
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G |
OPRM1 |
opioid receptor mu 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcium] inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]] |
CTD |
PMID:18652891 |
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NCBI chr 6:154,010,496...154,246,867
Ensembl chr 6:154,010,496...154,246,867
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G |
OR1D2 |
olfactory receptor family 1 subfamily D member 2 |
multiple interactions |
EXP |
[bourgeonal binds to and results in increased activity of OR1D2 protein] which results in increased abundance of Calcium |
CTD |
PMID:21454470 |
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NCBI chr17:3,088,484...3,104,422
Ensembl chr17:3,088,484...3,104,422
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G |
OR5D18 |
olfactory receptor family 5 subfamily D member 18 |
multiple interactions |
ISO |
[ethyl vanillin binds to and results in increased activity of OR5D18 protein] which results in increased transport of Calcium; [Eugenol binds to and results in increased activity of OR5D18 protein] which results in increased transport of Calcium; [Eugenol binds to OR5D18 protein] which results in increased transport of Calcium; [isomethyleugenol binds to and results in decreased activity of OR5D18 protein] which results in decreased transport of Calcium; isomethyleugenol inhibits the reaction [[Eugenol binds to OR5D18 protein] which results in increased transport of Calcium] |
CTD |
PMID:14685265 PMID:15716417 |
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NCBI chr11:55,819,630...55,820,571
Ensembl chr11:55,819,630...55,820,571
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G |
ORAI1 |
ORAI calcium release-activated calcium modulator 1 |
multiple interactions increases uptake |
ISO |
[Calcium affects the activity of and affects the localization of STIM1 protein] which affects the activity of ORAI1 protein ORAI1 protein results in increased uptake of Calcium |
CTD |
PMID:23212906 PMID:24990931 |
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NCBI chr12:121,626,530...121,643,109
Ensembl chr12:121,626,509...121,643,218
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G |
OXT |
oxytocin/neurophysin I prepropeptide |
multiple interactions |
EXP ISO |
OXT protein promotes the reaction [TRPC3 protein results in increased transport of Calcium] [Thapsigargin results in increased transport of Calcium] which results in increased secretion of OXT protein |
CTD |
PMID:12700192 PMID:22028774 |
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NCBI chr20:3,071,620...3,072,517
Ensembl chr20:3,071,620...3,072,517
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G |
P2RX3 |
purinergic receptor P2X 3 |
multiple interactions |
EXP |
[alpha,beta-methyleneadenosine 5'-triphosphate binds to and results in increased activity of P2RX3 protein] which results in increased abundance of Calcium; Trichloroethylene inhibits the reaction [[alpha,beta-methyleneadenosine 5'-triphosphate binds to and results in increased activity of P2RX3 protein] which results in increased abundance of Calcium] |
CTD |
PMID:12694404 |
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NCBI chr11:57,335,950...57,372,396
Ensembl chr11:57,338,352...57,372,396
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G |
P2RX7 |
purinergic receptor P2X 7 |
multiple interactions |
EXP |
[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium; KN 62 inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium]; protoberberine analog inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium] |
CTD |
PMID:21320518 |
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NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032
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G |
P2RY1 |
purinergic receptor P2Y1 |
multiple interactions |
EXP ISO |
[Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein] which results in increased abundance of Calcium; Calcium affects the reaction [P2RY1 protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; Trichloroethylene inhibits the reaction [[Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein] which results in increased abundance of Calcium] [N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate binds to and results in decreased activity of P2RY1 protein] inhibits the reaction [Adenosine Triphosphate results in increased uptake of Calcium] |
CTD |
PMID:12694404 PMID:16236484 PMID:16973929 |
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NCBI chr 3:152,835,131...152,841,439
Ensembl chr 3:152,835,131...152,841,439
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G |
P2RY2 |
purinergic receptor P2Y2 |
multiple interactions affects response to substance |
EXP ISO |
[Adenosine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Calcium P2RY2 protein affects the susceptibility to Calcium [Adenosine Triphosphate results in increased activity of P2RY2 protein] which results in increased uptake of Calcium; Go 6976 promotes the reaction [P2RY2 protein results in increased uptake of Calcium]; Tetradecanoylphorbol Acetate inhibits the reaction [P2RY2 protein results in increased uptake of Calcium] |
CTD |
PMID:11527950 PMID:17003265 PMID:18343036 |
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NCBI chr11:73,218,281...73,242,427
Ensembl chr11:73,218,281...73,242,427
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G |
P2RY4 |
pyrimidinergic receptor P2Y4 |
multiple interactions |
EXP |
[Adenosine Triphosphate binds to and results in increased activity of P2RY4 protein] which results in increased abundance of Calcium; Trichloroethylene inhibits the reaction [[Adenosine Triphosphate binds to and results in increased activity of P2RY4 protein] which results in increased abundance of Calcium] |
CTD |
PMID:12694404 |
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NCBI chr X:70,258,166...70,260,204
Ensembl chr X:70,258,166...70,260,204
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G |
P4HB |
prolyl 4-hydroxylase subunit beta |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of P4HB mRNA |
CTD |
PMID:15913539 |
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NCBI chr17:81,843,166...81,860,535
Ensembl chr17:81,843,159...81,860,856
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G |
PAFAH1B1 |
platelet activating factor acetylhydrolase 1b regulatory subunit 1 |
increases abundance multiple interactions |
EXP ISO |
PAFAH1B1 protein results in increased abundance of Calcium Calcium promotes the reaction [PAFAH1B1 protein binds to IQGAP1 protein binds to CDC42 protein] PKD1 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium]; PKD2 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium] |
CTD |
PMID:15001556 PMID:16369480 |
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NCBI chr17:2,593,183...2,685,615
Ensembl chr17:2,593,210...2,685,615
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G |
PARG |
poly(ADP-ribose) glycohydrolase |
multiple interactions |
ISO |
PARG protein promotes the reaction [Hydrogen Peroxide results in increased uptake of Calcium] |
CTD |
PMID:20878536 |
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NCBI chr10:49,818,279...49,942,027
Ensembl chr10:49,818,279...49,970,203
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G |
PARP1 |
poly(ADP-ribose) polymerase 1 |
multiple interactions |
ISO |
PARP1 protein promotes the reaction [Hydrogen Peroxide results in increased uptake of Calcium] |
CTD |
PMID:20878536 |
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NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
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G |
PASK |
PAS domain containing serine/threonine kinase |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of PASK mRNA |
CTD |
PMID:15913539 |
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NCBI chr 2:241,106,099...241,150,347
Ensembl chr 2:241,106,099...241,150,264
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G |
PAX6 |
paired box 6 |
affects expression |
ISO |
Calcium affects the expression of PAX6 mRNA |
CTD |
PMID:15913539 |
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NCBI chr11:31,789,026...31,817,961
Ensembl chr11:31,784,779...31,817,961
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G |
PAX8 |
paired box 8 |
affects expression |
ISO |
Calcium affects the expression of PAX8 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 2:113,215,997...113,278,921
Ensembl chr 2:113,215,997...113,278,921
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G |
PCDH19 |
protocadherin 19 |
affects binding |
EXP |
Calcium binds to PCDH19 protein |
CTD |
PMID:18469813 |
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NCBI chr X:100,291,644...100,410,273
Ensembl chr X:100,291,644...100,410,273
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G |
PDGFB |
platelet derived growth factor subunit B |
increases import |
EXP |
PDGFB protein results in increased import of Calcium |
CTD |
PMID:19576918 |
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NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982
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G |
PDK1 |
pyruvate dehydrogenase kinase 1 |
affects abundance multiple interactions |
ISO EXP |
PDK1 protein affects the abundance of Calcium PDK1 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein] 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester affects the reaction [PDK1 protein affects the abundance of Calcium]; [PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium; Adenosine Triphosphate promotes the reaction [PDK1 protein affects the abundance of Calcium]; PDK1 protein affects the reaction [Thapsigargin affects the abundance of Calcium]; tubacin affects the reaction [[PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium]; tubacin affects the reaction [PDK1 protein affects the abundance of Calcium]; tubacin inhibits the reaction [PDK1 protein affects the reaction [Thapsigargin affects the abundance of Calcium]] |
CTD |
PMID:28634229 PMID:28887310 |
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NCBI chr 2:172,555,373...172,724,312
Ensembl chr 2:172,555,373...172,608,669
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G |
PGP |
phosphoglycolate phosphatase |
decreases activity |
ISO |
Calcium results in decreased activity of PGP protein |
CTD |
PMID:24338473 |
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NCBI chr16:2,211,593...2,214,840
Ensembl chr16:2,211,593...2,214,840
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G |
PICK1 |
protein interacting with PRKCA 1 |
multiple interactions |
ISO |
Calcium affects the reaction [PICK1 protein binds to AGO2 protein]; Calcium deficiency inhibits the reaction [Excitatory Amino Acid Agonists inhibits the reaction [PICK1 protein binds to AGO2 protein]]; Calcium promotes the reaction [PICK1 protein binds to GRIA2 protein] |
CTD |
PMID:28404816 |
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NCBI chr22:38,057,255...38,075,701
Ensembl chr22:38,056,311...38,075,701
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G |
PIK3CB |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
affects transport |
ISO |
PIK3CB protein affects the transport of Calcium |
CTD |
PMID:11597992 |
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NCBI chr 3:138,652,698...138,834,928
Ensembl chr 3:138,652,698...138,834,928
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G |
PIK3CD |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta |
affects transport |
ISO |
PIK3CD protein affects the transport of Calcium |
CTD |
PMID:16179367 |
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NCBI chr 1:9,627,258...9,729,114
Ensembl chr 1:9,629,889...9,729,114
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G |
PIP5K1B |
phosphatidylinositol-4-phosphate 5-kinase type 1 beta |
affects expression |
ISO |
Calcium affects the expression of PIP5K1B mRNA |
CTD |
PMID:15913539 |
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NCBI chr 9:68,705,240...69,009,176
Ensembl chr 9:68,705,240...69,009,176
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G |
PKD1 |
polycystin 1, transient receptor potential channel interacting |
multiple interactions |
EXP ISO |
PKD1 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium] PKD1 protein affects the reaction [Caffeine affects the abundance of Calcium]; PKD1 protein affects the reaction [Thapsigargin affects the abundance of Calcium] |
CTD |
PMID:15001556 PMID:18679710 |
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NCBI chr16:2,088,708...2,135,898
Ensembl chr16:2,088,708...2,135,898
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G |
PKD2 |
polycystin 2, transient receptor potential cation channel |
increases transport multiple interactions |
EXP ISO |
PKD2 protein results in increased transport of Calcium PKD2 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium] IFT88 protein affects the reaction [PKD2 protein results in increased uptake of Calcium] |
CTD |
PMID:15001556 PMID:15100357 PMID:16396941 |
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NCBI chr 4:88,007,635...88,077,777
Ensembl chr 4:88,007,635...88,077,777
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G |
PKLR |
pyruvate kinase L/R |
multiple interactions |
ISO |
Calcium inhibits the reaction [Phenylephrine results in decreased activity of PKLR protein] |
CTD |
PMID:747652 |
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NCBI chr 1:155,289,293...155,308,654
Ensembl chr 1:155,289,293...155,301,438
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G |
PLA2G1B |
phospholipase A2 group IB |
multiple interactions increases abundance |
EXP |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[PLA2G1B protein results in increased abundance of Calcium] which results in increased expression of CXCL8 protein]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [PLA2G1B protein results in increased abundance of Calcium]; [PLA2G1B protein results in increased abundance of Calcium] which results in increased expression of CXCL8 protein |
CTD |
PMID:15528384 |
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NCBI chr12:120,322,115...120,327,779
Ensembl chr12:120,322,115...120,327,779
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G |
PLA2G2A |
phospholipase A2 group IIA |
increases uptake multiple interactions |
ISO |
PLA2G2A protein results in increased uptake of Calcium BQ 788 inhibits the reaction [EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium]]; EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium] |
CTD |
PMID:15695168 |
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NCBI chr 1:19,975,431...19,980,434
Ensembl chr 1:19,975,431...19,980,416
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G |
PLA2G6 |
phospholipase A2 group VI |
increases activity multiple interactions |
ISO |
Calcium deficiency results in increased activity of PLA2G6 protein 6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2H-pyran-2-one inhibits the reaction [[Lipopolysaccharides results in increased expression of and results in increased activity of PLA2G6 protein] which results in increased susceptibility to Calcium]; [Lipopolysaccharides results in increased expression of and results in increased activity of PLA2G6 protein] which results in increased susceptibility to Calcium |
CTD |
PMID:17885217 PMID:21178110 |
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NCBI chr22:38,111,495...38,181,830
Ensembl chr22:38,111,495...38,214,778
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G |
PLCG2 |
phospholipase C gamma 2 |
multiple interactions |
EXP |
Calcium promotes the reaction [PLCG2 protein mutant form results in increased chemical synthesis of Inositol Phosphates]; Calcium promotes the reaction [PLCG2 protein results in increased chemical synthesis of Inositol Phosphates] |
CTD |
PMID:27542411 |
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NCBI chr16:81,779,291...81,962,685
Ensembl chr16:81,779,279...81,962,685
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G |
PNOC |
prepronociceptin |
decreases abundance |
ISO |
PNOC protein results in decreased abundance of Calcium |
CTD |
PMID:21039959 |
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NCBI chr 8:28,316,988...28,343,351
Ensembl chr 8:28,316,986...28,343,355
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G |
PON1 |
paraoxonase 1 |
increases activity multiple interactions |
EXP ISO |
Calcium results in increased activity of PON1 protein [Calcium results in increased activity of PON1 protein] which affects the susceptibility to O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate; [Calcium results in increased activity of PON1 protein] which affects the susceptibility to oxamyl; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Aldicarb; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to methylparaoxon; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Paraoxon [Calcium co-treated with 1,2-dioleoyl-sn-glycero-3-phosphoglycerol] results in increased stability of PON1 protein; [Calcium co-treated with Oleic Acid] results in increased stability of PON1 protein; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Aldicarb; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to methylparaoxon; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to oxamyl; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Paraoxon; Calcium promotes the reaction [Oleic Acid inhibits the reaction [4-hydroxymercuribenzoate results in decreased activity of PON1 protein]] |
CTD |
PMID:12871208 PMID:27132127 |
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NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
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G |
PON2 |
paraoxonase 2 |
affects abundance multiple interactions |
EXP |
PON2 gene polymorphism affects the abundance of Calcium Calcium inhibits the reaction [lead acetate results in decreased activity of PON2 protein] |
CTD |
PMID:16141008 PMID:22271317 |
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NCBI chr 7:95,404,862...95,435,028
Ensembl chr 7:95,404,862...95,435,329
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G |
POU6F1 |
POU class 6 homeobox 1 |
affects expression |
ISO |
Calcium affects the expression of POU6F1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr12:51,186,936...51,218,062
Ensembl chr12:51,186,936...51,218,062
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G |
PPARA |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
[GW 7647 binds to and results in increased activity of PPARA protein] affects the reaction [Glucose affects the abundance of Calcium]; [Oleylethanolamide binds to and results in increased activity of PPARA protein] affects the reaction [Glucose affects the abundance of Calcium]; [pirinixic acid binds to and results in increased activity of PPARA protein] affects the reaction [Glucose affects the abundance of Calcium] |
CTD |
PMID:19017711 |
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NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
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G |
PPP1CA |
protein phosphatase 1 catalytic subunit alpha |
affects expression |
ISO |
Calcium affects the expression of PPP1CA mRNA |
CTD |
PMID:15913539 |
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NCBI chr11:67,398,183...67,401,858
Ensembl chr11:67,398,181...67,421,183
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G |
PPP1CB |
protein phosphatase 1 catalytic subunit beta |
affects expression |
ISO |
Calcium affects the expression of PPP1CB mRNA |
CTD |
PMID:15913539 |
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NCBI chr 2:28,751,604...28,802,940
Ensembl chr 2:28,751,640...28,802,940
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G |
PPP1R15A |
protein phosphatase 1 regulatory subunit 15A |
multiple interactions |
ISO |
[Egtazic Acid co-treated with Calcium deficiency] results in increased expression of PPP1R15A mRNA |
CTD |
PMID:9878749 |
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NCBI chr19:48,872,421...48,876,058
Ensembl chr19:48,872,212...48,876,059
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G |
PPP2CA |
protein phosphatase 2 catalytic subunit alpha |
affects abundance affects transport |
ISO |
PPP2CA protein affects the abundance of Calcium PPP2CA protein affects the transport of Calcium |
CTD |
PMID:15247211 |
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NCBI chr 5:134,194,332...134,226,073
Ensembl chr 5:134,194,035...134,226,073
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G |
PPP3R1 |
protein phosphatase 3 regulatory subunit B, alpha |
multiple interactions affects response to substance |
ISO |
PPP3R1 gene mutant form inhibits the reaction [ATP2A2 protein affects the transport of Calcium]; PPP3R1 gene mutant form inhibits the reaction [SLC8A1 protein affects the transport of Calcium] PPP3R1 gene mutant form affects the susceptibility to Calcium |
CTD |
PMID:19700627 |
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NCBI chr 2:68,178,857...68,252,532
Ensembl chr 2:68,178,857...68,256,237
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G |
PRDX6 |
peroxiredoxin 6 |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of PRDX6 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 1:173,477,335...173,488,815
Ensembl chr 1:173,477,330...173,488,815
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G |
PRKCA |
protein kinase C alpha |
multiple interactions increases response to substance |
ISO |
[Tretinoin co-treated with Calcium] results in increased activity of PRKCA protein PRKCA protein results in increased susceptibility to Calcium |
CTD |
PMID:12388232 PMID:16114872 |
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NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743
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G |
PRKCB |
protein kinase C beta |
multiple interactions |
ISO |
Calcium inhibits the reaction [Chlordecone results in increased activity of PRKCB protein]; Calcium inhibits the reaction [Dicofol results in increased activity of PRKCB protein] |
CTD |
PMID:1724372 |
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NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611
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G |
PRKCD |
protein kinase C delta |
affects expression |
ISO |
Calcium affects the expression of PRKCD mRNA |
CTD |
PMID:15913539 |
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NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717
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G |
PRKCE |
protein kinase C epsilon |
multiple interactions increases phosphorylation affects response to substance |
ISO EXP |
PRKCE protein affects the reaction [Oxygen deficiency results in increased abundance of Calcium] Calcium results in increased phosphorylation of PRKCE protein chelerythrine inhibits the reaction [Calcium results in increased phosphorylation of PRKCE protein]; PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]] PRKCE protein affects the susceptibility to Calcium |
CTD |
PMID:15242976 PMID:16793902 PMID:17087917 PMID:21562303 |
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NCBI chr 2:45,651,279...46,187,990
Ensembl chr 2:45,651,345...46,187,990
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G |
PRKCG |
protein kinase C gamma |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcium] inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]] |
CTD |
PMID:18652891 |
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NCBI chr19:53,881,094...53,907,652
Ensembl chr19:53,879,190...53,907,652
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G |
PRKD1 |
protein kinase D1 |
multiple interactions |
EXP ISO |
PRKD1 promotes the reaction [Capsaicin results in increased uptake of Calcium] PRKD1 mutant form inhibits the reaction [Capsaicin results in increased uptake of Calcium] |
CTD |
PMID:15471852 |
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NCBI chr14:29,576,479...29,927,847
Ensembl chr14:29,576,479...30,191,898
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G |
PRKG1 |
protein kinase cGMP-dependent 1 |
increases response to substance |
ISO |
PRKG1 protein results in increased susceptibility to Calcium |
CTD |
PMID:16533816 |
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NCBI chr10:50,990,888...52,298,350
Ensembl chr10:50,990,888...52,298,423
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G |
PRL |
prolactin |
multiple interactions |
EXP |
Calcium inhibits the reaction [PRL protein binds to PRLR protein] |
CTD |
PMID:6197504 |
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NCBI chr 6:22,287,246...22,302,835
Ensembl chr 6:22,287,244...22,302,826
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G |
PRLR |
prolactin receptor |
affects expression multiple interactions |
ISO EXP |
Calcium affects the expression of PRLR mRNA Calcium inhibits the reaction [PRL protein binds to PRLR protein] |
CTD |
PMID:6197504 PMID:15913539 |
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NCBI chr 5:35,048,756...35,230,487
Ensembl chr 5:35,048,756...35,230,487
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G |
PROK2 |
prokineticin 2 |
multiple interactions increases abundance |
ISO |
PROKR1 protein affects the reaction [PROK2 protein results in increased abundance of Calcium] |
CTD |
PMID:16793879 PMID:17107623 |
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NCBI chr 3:71,771,655...71,785,148
Ensembl chr 3:71,771,655...71,785,206
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G |
PROKR1 |
prokineticin receptor 1 |
multiple interactions |
ISO |
PROKR1 protein affects the reaction [Capsaicin results in increased abundance of Calcium]; PROKR1 protein affects the reaction [PROK2 protein results in increased abundance of Calcium] |
CTD |
PMID:16793879 |
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NCBI chr 2:68,643,579...68,658,251
Ensembl chr 2:68,643,579...68,658,251
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G |
PTAFR |
platelet activating factor receptor |
multiple interactions |
ISO |
RGS4 protein inhibits the reaction [PTAFR protein affects the localization of and affects the abundance of Calcium] |
CTD |
PMID:11297424 |
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NCBI chr 1:28,147,166...28,193,856
Ensembl chr 1:28,147,166...28,193,936
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G |
PTGDR2 |
prostaglandin D2 receptor 2 |
multiple interactions |
EXP |
PTGDR2 protein affects the abundance of and affects the localization of Calcium |
CTD |
PMID:16256979 |
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NCBI chr11:60,850,933...60,855,950
Ensembl chr11:60,850,933...60,855,950
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G |
PTGER1 |
prostaglandin E receptor 1 |
multiple interactions increases abundance |
ISO |
17-phenyltrinorprostaglandin E2 inhibits the reaction [PTGER1 protein results in increased abundance of Calcium] |
CTD |
PMID:11809688 |
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NCBI chr19:14,472,466...14,475,354
Ensembl chr19:14,472,466...14,475,354
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G |
PTGER3 |
prostaglandin E receptor 3 |
multiple interactions |
ISO |
PTGER3 protein affects the reaction [Dinoprostone results in decreased transport of Calcium]; PTGER3 protein affects the reaction [ONO AE 248 results in decreased transport of Calcium] |
CTD |
PMID:12535167 |
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NCBI chr 1:70,852,358...71,047,816
Ensembl chr 1:70,852,353...71,047,816
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G |
PTGIR |
prostaglandin I2 receptor |
multiple interactions |
EXP |
[cicaprost results in increased activity of PTGIR protein] which results in increased abundance of Calcium |
CTD |
PMID:11895442 |
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NCBI chr19:46,610,687...46,625,089
Ensembl chr19:46,620,468...46,625,089
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G |
PTGS1 |
prostaglandin-endoperoxide synthase 1 |
affects expression |
ISO |
Calcium affects the expression of PTGS1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703
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G |
PTGS2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
EXP ISO |
Calcium affects the reaction [bisperoxovanadium results in increased expression of PTGS2 mRNA] Calcium deficiency inhibits the reaction [Serotonin results in increased expression of PTGS2 mRNA] Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA] |
CTD |
PMID:12493747 PMID:19782052 PMID:21262218 |
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NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
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G |
PTH |
parathyroid hormone |
multiple interactions increases stability increases abundance decreases abundance affects metabolic processing decreases expression |
EXP ISO |
[Calcitriol co-treated with Calcium] results in decreased expression of PTH protein; [Cholecalciferol co-treated with Calcium] results in decreased expression of PTH protein Calcium deficiency results in increased stability of PTH mRNA Calcium affects the reaction [Aluminum Compounds results in decreased expression of PTH mRNA]; Calcium affects the reaction [Aluminum Compounds results in decreased secretion of PTH protein]; Calcium affects the reaction [Calcitriol results in decreased expression of PTH mRNA]; Calcium affects the reaction [Calcitriol results in decreased secretion of PTH protein]; Calcium deficiency inhibits the reaction [KHSRP protein binds to PTH 3' UTR]; Calcium deficiency promotes the reaction [HNRNPD protein binds to PTH 3' UTR] PTH protein modified form results in increased abundance of Calcium PTH protein results in decreased abundance of Calcium PTH protein affects the metabolism of Calcium Calcium results in decreased expression of PTH protein |
CTD |
PMID:80633 PMID:6330156 PMID:15891005 PMID:16094769 PMID:16316325 PMID:17476578 PMID:18583400 More...
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NCBI chr11:13,492,054...13,496,181
Ensembl chr11:13,492,054...13,496,181
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G |
PTH1R |
parathyroid hormone 1 receptor |
affects expression |
ISO |
Calcium affects the expression of PTH1R mRNA |
CTD |
PMID:15913539 |
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NCBI chr 3:46,877,721...46,903,799
Ensembl chr 3:46,877,721...46,903,799
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G |
PTK2B |
protein tyrosine kinase 2 beta |
multiple interactions |
EXP ISO |
Calcium affects the reaction [(N)-methanocarba-2MeSADP results in increased phosphorylation of PTK2B protein] Calcium affects the phosphorylation of and affects the activity of PTK2B protein |
CTD |
PMID:16236484 PMID:16877402 |
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NCBI chr 8:27,310,506...27,459,391
Ensembl chr 8:27,311,482...27,459,391
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G |
PTPN12 |
protein tyrosine phosphatase non-receptor type 12 |
affects expression |
ISO |
Calcium affects the expression of PTPN12 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 7:77,537,295...77,640,069
Ensembl chr 7:77,537,295...77,640,069
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G |
PYGL |
glycogen phosphorylase L |
multiple interactions |
ISO |
[Phenylephrine co-treated with Calcium] results in increased activity of PYGL protein; Calcium deficiency inhibits the reaction [Calcimycin results in increased activity of PYGL protein]; Glucose inhibits the reaction [[Phenylephrine co-treated with Calcium] results in increased activity of PYGL protein] |
CTD |
PMID:747652 PMID:6430282 |
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NCBI chr14:50,905,217...50,944,483
Ensembl chr14:50,857,891...50,944,483
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G |
RAB7A |
RAB7A, member RAS oncogene family |
affects expression |
ISO |
Calcium affects the expression of RAB7 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 3:128,726,183...128,814,798
Ensembl chr 3:128,693,669...128,825,942
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G |
RALGDS |
ral guanine nucleotide dissociation stimulator |
affects expression |
ISO |
Calcium affects the expression of RALGDS mRNA |
CTD |
PMID:15913539 |
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NCBI chr 9:133,097,722...133,149,210
Ensembl chr 9:133,097,720...133,149,334
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G |
RAP1A |
RAP1A, member of RAS oncogene family |
multiple interactions |
EXP |
Calcium promotes the reaction [ibandronic acid results in decreased prenylation of RAP1A protein] |
CTD |
PMID:18190680 |
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NCBI chr 1:111,542,009...111,716,691
Ensembl chr 1:111,542,218...111,716,691
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G |
RAPGEF3 |
Rap guanine nucleotide exchange factor 3 |
multiple interactions |
EXP |
RAPGEF3 protein promotes the reaction [Benzo(a)pyrene results in increased transport of Calcium] |
CTD |
PMID:22167199 |
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NCBI chr12:47,734,363...47,758,880
Ensembl chr12:47,734,363...47,771,040
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G |
RBP1 |
retinol binding protein 1 |
affects expression |
ISO |
Calcium affects the expression of RBP1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 3:139,517,438...139,539,742
Ensembl chr 3:139,517,434...139,539,829
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G |
REN |
renin |
decreases secretion multiple interactions |
ISO |
Calcium results in decreased secretion of REN protein [[Calcium results in increased activity of MYLK protein] which results in increased phosphorylation of MYL9 protein] which results in decreased secretion of REN protein; ML 7 inhibits the reaction [Calcium results in decreased secretion of REN protein] |
CTD |
PMID:9618396 |
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NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324
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G |
RGS4 |
regulator of G protein signaling 4 |
multiple interactions |
ISO |
RGS4 protein inhibits the reaction [PTAFR protein affects the localization of and affects the abundance of Calcium] |
CTD |
PMID:11297424 |
|
NCBI chr 1:163,068,871...163,076,802
Ensembl chr 1:163,068,775...163,076,802
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G |
RPS3A |
ribosomal protein S3A |
affects expression |
ISO |
Calcium affects the expression of RPS3A mRNA |
CTD |
PMID:15913539 |
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NCBI chr 4:151,099,628...151,104,642
Ensembl chr 4:151,099,624...151,104,642
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G |
RPS6KB1 |
ribosomal protein S6 kinase B1 |
multiple interactions |
ISO EXP |
Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of RPS6KB1 protein] [Resveratrol results in increased abundance of Calcium] which results in decreased expression of RPS6KB1 protein modified form; dorsomorphin inhibits the reaction [[Resveratrol results in increased abundance of Calcium] which results in decreased expression of RPS6KB1 protein modified form] |
CTD |
PMID:12935885 PMID:23680031 |
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NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574
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G |
RPTOR |
regulatory associated protein of MTOR complex 1 |
multiple interactions |
EXP |
[Resveratrol results in increased abundance of Calcium] which results in increased activity of RPTOR protein modified form; dorsomorphin inhibits the reaction [[Resveratrol results in increased abundance of Calcium] which results in increased activity of RPTOR protein modified form] |
CTD |
PMID:23680031 |
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NCBI chr17:80,544,838...80,966,368
Ensembl chr17:80,544,819...80,966,371
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G |
RRAGA |
Ras related GTP binding A |
affects expression |
ISO |
Calcium affects the expression of RRAGA mRNA |
CTD |
PMID:15913539 |
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NCBI chr 9:19,049,427...19,051,025
Ensembl chr 9:19,049,427...19,051,025
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G |
RYR1 |
ryanodine receptor 1 |
multiple interactions affects abundance increases secretion increases abundance |
EXP ISO |
[Caffeine results in increased activity of RYR1 protein] which affects the localization of Calcium; [chlorocresol results in increased activity of RYR1 protein] which affects the localization of Calcium; [chlorocresol results in increased activity of RYR1 protein] which results in increased transport of Calcium; [Halothane results in increased activity of RYR1 protein] which affects the localization of Calcium; [RYR1 protein co-treated with 2,3,6,2',3',6'-hexachlorobiphenyl] affects the susceptibility to Calcium; Calcium affects the folding of [CALM1 protein binds to RYR1 protein modified form]; Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]; Dantrolene inhibits the reaction [[chlorocresol results in increased activity of RYR1 protein] which results in increased transport of Calcium]; RYR1 protein polymorphism affects the reaction [Caffeine results in increased secretion of Calcium]; RYR1 protein polymorphism affects the reaction [chlorocresol results in increased secretion of Calcium] RYR1 protein polymorphism affects the abundance of Calcium RYR1 protein mutant form results in increased secretion of Calcium RYR1 gene mutant form results in increased abundance of Calcium Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]; Calcium affects the reaction [CALM1 protein modified form binds to and affects the activity of RYR1 protein] |
CTD |
PMID:15381065 PMID:15628869 PMID:16372898 PMID:17707769 PMID:18719443 PMID:18954145 PMID:19191329 PMID:21485675 More...
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NCBI chr19:38,433,691...38,587,564
Ensembl chr19:38,433,691...38,595,273
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G |
RYR2 |
ryanodine receptor 2 |
multiple interactions |
EXP ISO |
FKBP1A protein inhibits the reaction [Calcium results in increased activity of RYR2 protein] Dantrolene inhibits the reaction [Caffeine promotes the reaction [RYR2 protein results in increased secretion of Calcium]]; HOMER1 protein alternative form inhibits the reaction [Caffeine promotes the reaction [RYR2 protein results in increased secretion of Calcium]]; HOMER1 protein alternative form inhibits the reaction [Cyclic ADP-Ribose promotes the reaction [RYR2 protein results in increased secretion of Calcium]] |
CTD |
PMID:12887973 PMID:17872463 |
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NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988
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G |
S100A13 |
S100 calcium binding protein A13 |
multiple interactions |
EXP |
[Calcium co-treated with Copper] binds to and affects the folding of S100A13 protein; Calcium binds to and affects the folding of S100A13 protein |
CTD |
PMID:16766622 |
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NCBI chr 1:153,618,799...153,634,361
Ensembl chr 1:153,618,787...153,631,360
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G |
S100A2 |
S100 calcium binding protein A2 |
affects binding multiple interactions |
EXP |
Calcium binds to S100A2 protein [Zinc binds to S100A2 protein] inhibits the reaction [Calcium binds to S100A2 protein] |
CTD |
PMID:17239974 |
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NCBI chr 1:153,561,108...153,565,844
Ensembl chr 1:153,561,108...153,567,890
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G |
S100A6 |
S100 calcium binding protein A6 |
affects response to substance |
EXP |
S100A6 protein affects the susceptibility to Calcium |
CTD |
PMID:15068510 |
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NCBI chr 1:153,534,599...153,535,991
Ensembl chr 1:153,534,599...153,536,244
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G |
S100A8 |
S100 calcium binding protein A8 |
multiple interactions affects binding |
EXP |
[Zinc co-treated with Calcium] binds to [S100A8 protein binds to S100A9 protein] Calcium binds to [S100A8 protein binds to S100A9 protein] |
CTD |
PMID:17050004 |
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NCBI chr 1:153,390,032...153,422,583
Ensembl chr 1:153,390,032...153,391,073
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G |
S100A9 |
S100 calcium binding protein A9 |
affects binding multiple interactions |
EXP |
Calcium binds to [S100A8 protein binds to S100A9 protein] [Zinc co-treated with Calcium] binds to [S100A8 protein binds to S100A9 protein] |
CTD |
PMID:17050004 |
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NCBI chr 1:153,357,854...153,361,023
Ensembl chr 1:153,357,854...153,361,023
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G |
S100G |
S100 calcium binding protein G |
affects expression |
ISO |
Calcium affects the expression of S100G mRNA |
CTD |
PMID:15913539 |
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NCBI chr X:16,650,158...16,654,670
Ensembl chr X:16,650,158...16,654,670
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G |
SCGB1A1 |
secretoglobin family 1A member 1 |
increases expression |
EXP |
Calcium results in increased expression of SCGB1A1 mRNA; Calcium results in increased expression of SCGB1A1 protein |
CTD |
PMID:16237193 |
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NCBI chr11:62,419,033...62,423,195
Ensembl chr11:62,405,103...62,423,195
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G |
SCT |
secretin |
increases abundance |
EXP |
SCT protein results in increased abundance of Calcium |
CTD |
PMID:1220513 |
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NCBI chr11:626,309...627,181
Ensembl chr11:626,309...627,181
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G |
SEC61A1 |
SEC61 translocon subunit alpha 1 |
multiple interactions increases transport |
EXP |
[HSPA5 protein binds to SEC61A1 protein] which results in decreased transport of Calcium; [SEC61A1 protein results in increased transport of Calcium] which results in increased susceptibility to Thapsigargin; DNAJB11 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium]; DNAJC3 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium] |
CTD |
PMID:26085089 |
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NCBI chr 3:128,051,641...128,071,683
Ensembl chr 3:128,051,641...128,071,705
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G |
SELENOT |
selenoprotein T |
multiple interactions affects abundance |
ISO |
Calcium affects the reaction [ADCYAP1 protein results in increased expression of SELENOT mRNA]; SELENOT protein affects the reaction [ADCYAP1 protein results in increased abundance of Calcium]; Thapsigargin promotes the reaction [SELENOT protein affects the abundance of Calcium] |
CTD |
PMID:18198219 |
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NCBI chr 3:150,603,321...150,630,436
Ensembl chr 3:150,602,875...150,630,436
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G |
SERPINE1 |
serpin family E member 1 |
increases stability |
EXP |
Calcium results in increased stability of SERPINE1 protein |
CTD |
PMID:21280127 PMID:21280128 |
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NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
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G |
SLC12A5 |
solute carrier family 12 member 5 |
multiple interactions |
ISO |
Calcium affects the reaction [Zinc results in increased activity of SLC12A5 protein] |
CTD |
PMID:22441041 |
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NCBI chr20:46,021,686...46,060,150
Ensembl chr20:46,021,690...46,060,150
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G |
SLC23A2 |
solute carrier family 23 member 2 |
decreases expression multiple interactions increases expression |
ISO |
Calcium deficiency results in decreased expression of SLC23A2 mRNA Foscarnet inhibits the reaction [Calcium results in increased expression of SLC23A2 mRNA]; Nifedipine inhibits the reaction [Calcium results in increased expression of SLC23A2 mRNA] Calcium results in increased expression of SLC23A2 mRNA; Calcium results in increased expression of SLC23A2 protein |
CTD |
PMID:12788230 |
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NCBI chr20:4,852,358...5,010,313
Ensembl chr20:4,852,356...5,010,293
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G |
SLC24A2 |
solute carrier family 24 member 2 |
increases uptake |
ISO |
SLC24A2 protein results in increased uptake of Calcium |
CTD |
PMID:14660663 |
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NCBI chr 9:19,507,455...20,307,892
Ensembl chr 9:19,507,452...19,789,037
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G |
SLC2A1 |
solute carrier family 2 member 1 |
multiple interactions |
ISO |
Calcium deficiency inhibits the reaction [2,3-dinitrophenol results in increased activity of SLC2A1 protein]; Calcium deficiency inhibits the reaction [Arsenates results in increased activity of SLC2A1 protein]; Calcium deficiency inhibits the reaction [Azides results in increased activity of SLC2A1 protein]; Calcium deficiency inhibits the reaction [INS1 protein results in increased activity of SLC2A1 protein] |
CTD |
PMID:10970766 |
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NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893
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G |
SLC2A2 |
solute carrier family 2 member 2 |
multiple interactions |
ISO |
[CACNA1D protein results in increased uptake of Calcium] which affects the localization of SLC2A2 protein |
CTD |
PMID:17272349 |
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NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743
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G |
SLC2A4 |
solute carrier family 2 member 4 |
multiple interactions |
ISO |
[[Chloroquine results in increased abundance of Calcium] which affects the localization of SLC2A4 protein] which results in increased uptake of Glucose; [Chloroquine results in increased abundance of Calcium] which affects the localization of SLC2A4 protein |
CTD |
PMID:27160165 |
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NCBI chr17:7,281,718...7,288,257
Ensembl chr17:7,281,718...7,288,257
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G |
SLC30A1 |
solute carrier family 30 member 1 |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of SLC30A1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 1:211,571,568...211,579,161
Ensembl chr 1:211,571,568...211,579,161
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G |
SLC5A1 |
solute carrier family 5 member 1 |
multiple interactions |
ISO |
SLC5A1 protein affects the reaction [CACNA1D protein results in increased uptake of Calcium] |
CTD |
PMID:17272349 |
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NCBI chr22:32,043,261...32,113,029
Ensembl chr22:32,043,261...32,113,029
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G |
SLC8A1 |
solute carrier family 8 member A1 |
multiple interactions increases transport |
EXP ISO |
Calcium inhibits the reaction [SLC8A1 protein results in increased uptake of Nickel] SLC8A1 protein results in increased transport of Calcium 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [SLC8A1 protein results in increased transport of Calcium] PPP3R1 gene mutant form inhibits the reaction [SLC8A1 protein affects the transport of Calcium] |
CTD |
PMID:10329968 PMID:18822394 PMID:19700627 |
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NCBI chr 2:40,097,270...40,512,435
Ensembl chr 2:40,097,270...40,611,053
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G |
SLC8A2 |
solute carrier family 8 member A2 |
increases uptake |
ISO |
SLC8A2 protein results in increased uptake of Calcium |
CTD |
PMID:14660663 |
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NCBI chr19:47,428,017...47,471,893
Ensembl chr19:47,428,017...47,471,893
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G |
SLC8A3 |
solute carrier family 8 member A3 |
increases transport increases uptake |
ISO |
SLC8A3 protein results in increased transport of Calcium SLC8A3 protein results in increased uptake of Calcium |
CTD |
PMID:14660663 PMID:17585341 PMID:29434186 |
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NCBI chr14:70,044,215...70,189,405
Ensembl chr14:70,044,215...70,189,480
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G |
SLC9A1 |
solute carrier family 9 member A1 |
multiple interactions |
ISO |
3-methylsulfonyl-4-piperidinobenzoyl guanidine inhibits the reaction [[Phenylephrine results in increased activity of SLC9A1 protein] which results in increased transport of Calcium]; [[Phenylephrine results in increased activity of SLC9A1 protein] which results in increased transport of Calcium] which results in increased expression of ATP2A2 protein; [Phenylephrine results in increased activity of SLC9A1 protein] which results in increased transport of Calcium |
CTD |
PMID:16236312 |
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NCBI chr 1:27,098,809...27,155,125
Ensembl chr 1:27,098,809...27,166,981
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G |
SNCA |
synuclein alpha |
multiple interactions increases uptake |
ISO |
omega-Conotoxin GVIA inhibits the reaction [SNCA protein results in increased uptake of Calcium] |
CTD |
PMID:17179863 |
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NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315
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G |
SOD1 |
superoxide dismutase 1 |
multiple interactions increases transport |
EXP ISO |
SOD1 protein mutant form promotes the reaction [SOD1 protein binds to Calcium] SOD1 protein modified form results in increased transport of Calcium; SOD1 protein results in increased transport of Calcium [Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in decreased activity of SOD1 protein]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in decreased activity of SOD1 protein]; [Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of SOD1 protein]; Calcium affects the reaction [sodium arsenite results in decreased activity of SOD1 protein] |
CTD |
PMID:19227972 PMID:22534743 PMID:24184500 PMID:28085149 |
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NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
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G |
SOD2 |
superoxide dismutase 2 |
multiple interactions |
ISO |
[Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in decreased activity of SOD2 protein]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in decreased activity of SOD2 protein]; [Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of SOD2 protein]; Calcium affects the reaction [sodium arsenite results in decreased activity of SOD2 protein] |
CTD |
PMID:22534743 PMID:24184500 |
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NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
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G |
SP7 |
Sp7 transcription factor |
affects secretion |
ISO |
SP7 protein affects the secretion of Calcium |
CTD |
PMID:19064586 |
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NCBI chr12:53,326,575...53,344,793
Ensembl chr12:53,326,575...53,345,315
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G |
SPHK1 |
sphingosine kinase 1 |
multiple interactions |
EXP ISO |
[C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium; resveratrol inhibits the reaction [[C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium] |
CTD |
PMID:19284563 PMID:19346296 |
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NCBI chr17:76,383,204...76,387,855
Ensembl chr17:76,376,584...76,387,860
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G |
SPP1 |
secreted phosphoprotein 1 |
increases expression affects expression multiple interactions |
ISO |
Calcium results in increased expression of SPP1 mRNA Calcium affects the expression of SPP1 mRNA Foscarnet inhibits the reaction [Calcium results in increased expression of SPP1 mRNA]; Nifedipine inhibits the reaction [Calcium results in increased expression of SPP1 mRNA] |
CTD |
PMID:12788230 PMID:15913539 |
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NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
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G |
SPP2 |
secreted phosphoprotein 2 |
affects expression |
ISO |
Calcium affects the expression of SPP2 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 2:234,050,702...234,077,134
Ensembl chr 2:234,050,679...234,077,134
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G |
SPTAN1 |
spectrin alpha, non-erythrocytic 1 |
multiple interactions increases cleavage |
ISO |
((1S)-1-((((1S)-1-benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester inhibits the reaction [Calcium results in increased cleavage of SPTAN1 protein]; Edetic Acid inhibits the reaction [Calcium results in increased cleavage of SPTAN1 protein]; N-(4-fluorophenylsulfonyl)-L-valyl-L-leucinal inhibits the reaction [Calcium results in increased cleavage of SPTAN1 protein] |
CTD |
PMID:17069801 |
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NCBI chr 9:128,552,587...128,633,662
Ensembl chr 9:128,552,558...128,633,662
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G |
SQSTM1 |
sequestosome 1 |
affects expression |
ISO |
Calcium affects the expression of SQSTM1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
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G |
SRC |
SRC proto-oncogene, non-receptor tyrosine kinase |
affects transport multiple interactions affects response to substance |
ISO |
SRC protein affects the transport of Calcium Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of SRC protein] SRC protein affects the susceptibility to Calcium |
CTD |
PMID:17551092 PMID:19782052 |
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NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050
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G |
STAR |
steroidogenic acute regulatory protein |
multiple interactions |
ISO |
Calcium inhibits the reaction [Cyclic AMP results in increased expression of STAR protein] |
CTD |
PMID:19822634 |
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NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
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G |
STAT1 |
signal transducer and activator of transcription 1 |
multiple interactions |
EXP |
Calcium promotes the reaction [[Diclofenac co-treated with IFNG protein] results in increased phosphorylation of STAT1 protein] |
CTD |
PMID:26609140 |
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NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960
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G |
STIM1 |
stromal interaction molecule 1 |
affects abundance increases uptake multiple interactions |
EXP ISO |
STIM1 protein affects the abundance of Calcium STIM1 protein results in increased uptake of Calcium [Calcium affects the activity of and affects the localization of STIM1 protein] which affects the activity of ORAI1 protein; STIM1 protein promotes the reaction [Taurodeoxycholic Acid results in increased abundance of Calcium] |
CTD |
PMID:18342630 PMID:18439569 PMID:23212906 PMID:24990931 |
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NCBI chr11:3,854,604...4,093,210
Ensembl chr11:3,854,527...4,093,210
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G |
STMN1 |
stathmin 1 |
affects expression |
ISO |
Calcium affects the expression of STMN1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 1:25,884,179...25,906,880
Ensembl chr 1:25,884,181...25,906,991
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G |
SUGT1 |
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone |
multiple interactions |
EXP |
Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to SUGT1 protein]] |
CTD |
PMID:23184943 |
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NCBI chr13:52,652,836...52,700,909
Ensembl chr13:52,652,709...52,700,909
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G |
SYN2 |
synapsin II |
multiple interactions decreases abundance |
ISO |
SYN2 mutant form inhibits the reaction [Adenosine Triphosphate results in increased abundance of Calcium] SYN2 mutant form results in decreased abundance of Calcium |
CTD |
PMID:18701217 |
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NCBI chr 3:12,004,388...12,192,032
Ensembl chr 3:12,004,388...12,192,032
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G |
SYT1 |
synaptotagmin 1 |
affects binding |
ISO |
Calcium binds to SYT1 protein |
CTD |
PMID:16262243 |
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NCBI chr12:78,863,982...79,452,008
Ensembl chr12:78,863,993...79,452,008
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G |
TAC1 |
tachykinin precursor 1 |
increases transport |
ISO |
TAC1 protein modified form results in increased transport of Calcium |
CTD |
PMID:30116771 |
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NCBI chr 7:97,732,086...97,740,472
Ensembl chr 7:97,732,084...97,740,472
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G |
TAOK1 |
TAO kinase 1 |
affects expression |
ISO |
Calcium affects the expression of TAOK1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr17:29,390,363...29,551,903
Ensembl chr17:29,390,363...29,551,903
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G |
TBXA2R |
thromboxane A2 receptor |
multiple interactions increases transport |
EXP |
rosiglitazone inhibits the reaction [TBXA2R protein results in increased transport of Calcium]; troglitazone inhibits the reaction [TBXA2R protein results in increased transport of Calcium] |
CTD |
PMID:16499875 |
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NCBI chr19:3,594,507...3,606,875
Ensembl chr19:3,594,507...3,606,875
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G |
TGFA |
transforming growth factor alpha |
increases abundance |
EXP |
TGFA protein results in increased abundance of Calcium |
CTD |
PMID:11527950 |
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NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193
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G |
TGFB1 |
transforming growth factor beta 1 |
increases abundance increases uptake |
EXP ISO |
TGFB1 protein results in increased abundance of Calcium TGFB1 protein results in increased uptake of Calcium |
CTD |
PMID:15703175 PMID:17090780 |
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NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
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G |
TGM1 |
transglutaminase 1 |
increases expression multiple interactions |
EXP |
Calcium results in increased expression of TGM1 mRNA NPS R-467 promotes the reaction [Calcium results in increased expression of TGM1 mRNA] |
CTD |
PMID:10469331 |
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NCBI chr14:24,249,114...24,263,177
Ensembl chr14:24,249,114...24,264,432
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G |
TIMM17A |
translocase of inner mitochondrial membrane 17A |
affects expression |
ISO |
Calcium affects the expression of TIMM17A mRNA |
CTD |
PMID:15913539 |
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NCBI chr 1:201,955,503...201,970,664
Ensembl chr 1:201,955,503...201,970,664
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G |
TJP1 |
tight junction protein 1 |
multiple interactions |
EXP |
Calcium deficiency inhibits the reaction [TJP1 protein binds to OCLN protein] |
CTD |
PMID:11054866 |
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NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915
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G |
TNF |
tumor necrosis factor |
multiple interactions |
ISO EXP |
KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]] [IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]; [TNF protein co-treated with IFNG protein] promotes the reaction [Diclofenac affects the abundance of Calcium]; Calcium affects the reaction [Morphine inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]] |
CTD |
PMID:23747339 PMID:24068670 PMID:26609140 |
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NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
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G |
TNFAIP6 |
TNF alpha induced protein 6 |
multiple interactions |
EXP |
Calcium promotes the reaction [ITIH1 protein binds to TNFAIP6 protein]; Calcium promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] |
CTD |
PMID:16768462 |
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NCBI chr 2:151,357,592...151,381,340
Ensembl chr 2:151,357,592...151,380,046
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G |
TNFRSF11B |
TNF receptor superfamily member 11b |
multiple interactions |
ISO |
TNFRSF11B protein inhibits the reaction [IL11 protein results in increased abundance of Calcium]; TNFRSF11B protein inhibits the reaction [TNFSF11 protein results in increased abundance of Calcium] |
CTD |
PMID:12110441 |
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NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885
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G |
TNFSF11 |
TNF superfamily member 11 |
multiple interactions increases abundance |
ISO |
TNFRSF11B protein inhibits the reaction [TNFSF11 protein results in increased abundance of Calcium] |
CTD |
PMID:12110441 |
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NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013
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G |
TNNC1 |
troponin C1, slow skeletal and cardiac type |
affects binding |
EXP |
TNNC1 protein binds to Calcium |
CTD |
PMID:18212018 |
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NCBI chr 3:52,451,100...52,454,041
Ensembl chr 3:52,451,100...52,454,041
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G |
TP53 |
tumor protein p53 |
decreases expression affects localization |
EXP |
Calcium results in decreased expression of TP53 protein TP53 protein affects the localization of Calcium |
CTD |
PMID:15059885 PMID:16043423 |
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NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
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G |
TP73 |
tumor protein p73 |
multiple interactions |
EXP |
[Calcium co-treated with CAPN1 protein] results in increased degradation of TP73 protein modified form |
CTD |
PMID:21516125 |
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NCBI chr 1:3,652,516...3,736,201
Ensembl chr 1:3,652,516...3,736,201
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G |
TRPA1 |
transient receptor potential cation channel subfamily A member 1 |
affects activity multiple interactions |
ISO EXP |
Calcium affects the activity of TRPA1 protein [allicin binds to and results in increased activity of TRPA1 protein] which results in increased transport of Calcium; [allyl isothiocyanate binds to and results in increased activity of TRPA1 protein] which results in increased transport of Calcium; [cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester co-treated with TRPA1 protein] results in increased uptake of Calcium; Calcium affects the reaction [Capsaicin inhibits the reaction [TRPA1 protein affects the susceptibility to mustard oil]]; TRPA1 affects the reaction [AM 1241 results in increased abundance of Calcium]; TRPA1 promotes the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased abundance of Calcium]; TRPA1 promotes the reaction [mustard oil results in increased abundance of Calcium] 4-(4-chlorophenyl)-3-methylbut-3-en-2-oxime inhibits the reaction [[2-chloroethyl ethyl sulfide results in increased activity of TRPA1 protein] which results in increased uptake of Calcium]; 4-(4-chlorophenyl)-3-methylbut-3-en-2-oxime inhibits the reaction [[Mustard Gas results in increased activity of TRPA1 protein] which results in increased uptake of Calcium]; [2-chloroethyl ethyl sulfide results in increased activity of TRPA1 protein] which results in increased uptake of Calcium; [allyl isothiocyanate results in increased activity of TRPA1 protein] which results in increased uptake of Calcium; [cannabidivarin results in increased activity of TRPA1 protein] which results in increased uptake of Calcium; [Cannabinol results in increased activity of TRPA1 protein] which results in increased uptake of Calcium; [cinnamaldehyde results in increased activity of TRPA1 protein] which results in increased transport of Calcium; [cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester co-treated with TRPA1 protein] results in increased uptake of Calcium; [hydroquinone results in increased activity of TRPA1 protein] which results in increased import of Calcium; [Mustard Gas results in increased activity of TRPA1 protein] which results in increased uptake of Calcium; [Pyruvaldehyde results in increased activity of TRPA1 protein] which results in increased transport of Calcium; [Vehicle Emissions results in increased activity of TRPA1 protein] which results in increased import of Calcium; Acetylcysteine inhibits the reaction [[allyl isothiocyanate results in increased activity of TRPA1 protein] which results in increased uptake of Calcium]; Acetylcysteine inhibits the reaction [[Mustard Gas results in increased activity of TRPA1 protein] which results in increased uptake of Calcium]; Dithiothreitol inhibits the reaction [[hydroquinone results in increased activity of TRPA1 protein] which results in increased import of Calcium]; mustard oil promotes the reaction [[hydroquinone results in increased activity of TRPA1 protein] which results in increased import of Calcium]; TRPA1 mRNA affects the reaction [Acrolein results in increased uptake of Calcium]; TRPA1 mRNA affects the reaction [allyl isothiocyanate results in increased uptake of Calcium]; TRPA1 mRNA affects the reaction [cinnamaldehyde results in increased uptake of Calcium] |
CTD |
PMID:15843607 PMID:17314320 PMID:17590514 PMID:18234885 PMID:19507004 PMID:20086034 PMID:22863862 PMID:27738742 PMID:28790335 PMID:30945539 PMID:31096838 More...
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NCBI chr 8:72,021,250...72,090,010
Ensembl chr 8:72,019,917...72,075,584
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G |
TRPC1 |
transient receptor potential cation channel subfamily C member 1 |
increases uptake increases import increases transport decreases transport multiple interactions |
ISO EXP |
TRPC1 protein results in increased uptake of Calcium TRPC1 protein results in increased import of Calcium TRPC1 protein results in increased transport of Calcium TRPC1 protein results in decreased transport of Calcium LEP protein promotes the reaction [TRPC1 protein results in increased transport of Calcium] |
CTD |
PMID:17174323 PMID:18822394 PMID:20107083 PMID:22157757 PMID:24953315 |
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NCBI chr 3:142,724,034...142,807,888
Ensembl chr 3:142,724,034...142,807,888
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G |
TRPC3 |
transient receptor potential cation channel subfamily C member 3 |
multiple interactions increases transport affects transport affects secretion |
EXP ISO |
1-oleoyl-2-acetylglycerol affects the reaction [TRPC3 protein affects the transport of Calcium]; 1-oleoyl-2-acetylglycerol promotes the reaction [TRPC3 protein results in increased transport of Calcium]; OXT protein promotes the reaction [TRPC3 protein results in increased transport of Calcium]; Thapsigargin promotes the reaction [TRPC3 protein results in increased transport of Calcium] TRPC3 protein affects the secretion of Calcium 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [[Phenylephrine results in increased expression of TRPC3 protein] which results in increased transport of Calcium]; [Phenylephrine results in increased expression of TRPC3 protein] which results in increased transport of Calcium; TRPC3 protein promotes the reaction [1-oleoyl-2-acetoyl-sn-glycerol results in increased transport of Calcium]; TRPC3 protein promotes the reaction [Phenylephrine results in increased transport of Calcium]; TRPC3 protein promotes the reaction [Thapsigargin results in increased transport of Calcium] |
CTD |
PMID:12700192 PMID:12736256 PMID:15672411 PMID:16484216 PMID:17351372 PMID:18822394 PMID:19244478 More...
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NCBI chr 4:121,874,481...121,952,060
Ensembl chr 4:121,874,481...121,952,060
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G |
TRPC4 |
transient receptor potential cation channel subfamily C member 4 |
multiple interactions increases transport |
EXP ISO |
TRPC4 protein affects the reaction [Arachidonic Acid results in increased transport of Calcium]; TRPC4 protein affects the reaction [Carbachol results in increased transport of Calcium] TRPC4 protein results in increased transport of Calcium LEP protein promotes the reaction [TRPC4 protein results in increased transport of Calcium] |
CTD |
PMID:11830588 PMID:20107083 |
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NCBI chr13:37,632,063...37,869,772
Ensembl chr13:37,632,063...37,869,802
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G |
TRPC5 |
transient receptor potential cation channel subfamily C member 5 |
multiple interactions increases transport affects transport |
EXP ISO |
1-oleoyl-2-acetylglycerol affects the reaction [TRPC5 protein affects the transport of Calcium]; 2-aminoethoxydiphenyl borate promotes the reaction [resveratrol inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]]; Ascorbic Acid inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; Calcium promotes the reaction [resveratrol inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]]; Carbachol promotes the reaction [TRPC5 protein results in increased transport of Calcium]; CAT protein inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; CAT protein inhibits the reaction [Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; Diethylstilbestrol inhibits the reaction [TRPC5 protein results in increased transport of Calcium]; Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]; Gallic Acid inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; Gallic Acid inhibits the reaction [Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]; Lysophosphatidylcholines promotes the reaction [TRPC5 protein results in increased transport of Calcium]; resveratrol inhibits the reaction [Carbachol promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; resveratrol inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; resveratrol inhibits the reaction [Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; resveratrol inhibits the reaction [Lysophosphatidylcholines promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; resveratrol inhibits the reaction [TRPC5 protein results in increased transport of Calcium]; resveratrol promotes the reaction [Ascorbic Acid inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]] LEP protein promotes the reaction [TRPC5 protein results in increased transport of Calcium] |
CTD |
PMID:17351372 PMID:20107083 PMID:21127073 |
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NCBI chr X:111,768,011...112,082,776
Ensembl chr X:111,768,011...112,082,776
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G |
TRPC6 |
transient receptor potential cation channel subfamily C member 6 |
affects transport increases uptake multiple interactions increases transport |
EXP ISO |
TRPC6 protein affects the transport of Calcium TRPC6 protein results in increased uptake of Calcium 1,2-dioctanoylglycerol promotes the reaction [TRPC6 protein results in increased uptake of Calcium]; 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [1-oleoyl-2-acetoyl-sn-glycerol promotes the reaction [TRPC6 protein results in increased uptake of Calcium]]; 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [Acetylcholine promotes the reaction [TRPC6 protein results in increased uptake of Calcium]]; 1-oleoyl-2-acetoyl-sn-glycerol promotes the reaction [Acetylcholine promotes the reaction [TRPC6 protein results in increased uptake of Calcium]]; 1-oleoyl-2-acetoyl-sn-glycerol promotes the reaction [TRPC6 protein results in increased uptake of Calcium]; 2-aminoethyl diphenylborinate inhibits the reaction [Acetylcholine promotes the reaction [TRPC6 protein results in increased uptake of Calcium]]; 2-aminoethyl diphenylborinate inhibits the reaction [Thapsigargin promotes the reaction [TRPC6 protein results in increased uptake of Calcium]]; Acetylcholine promotes the reaction [TRPC6 protein results in increased uptake of Calcium]; Flufenamic Acid inhibits the reaction [1-oleoyl-2-acetoyl-sn-glycerol promotes the reaction [TRPC6 protein results in increased uptake of Calcium]]; Thapsigargin promotes the reaction [TRPC6 protein results in increased uptake of Calcium]; TRPC6 protein promotes the reaction [1-oleoyl-2-acetoyl-sn-glycerol results in increased transport of Calcium]; TRPC6 protein promotes the reaction [Phenylephrine results in increased transport of Calcium] [Diglycerides results in increased activity of TRPC6 protein] which results in increased abundance of Calcium; [Flufenamic Acid results in increased activity of TRPC6 protein] which results in increased uptake of Calcium; CASR protein promotes the reaction [TRPC6 protein results in increased uptake of Calcium]; TRPC6 protein promotes the reaction [[VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium]; VEGFA protein promotes the reaction [[Diglycerides results in increased activity of TRPC6 protein] which results in increased abundance of Calcium] TRPC6 protein results in increased transport of Calcium |
CTD |
PMID:11179201 PMID:11535132 PMID:14551041 PMID:15672411 PMID:18209485 PMID:18822394 PMID:21562303 More...
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NCBI chr11:101,451,564...101,584,007
Ensembl chr11:101,451,564...101,872,562
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G |
TRPM2 |
transient receptor potential cation channel subfamily M member 2 |
increases transport multiple interactions |
EXP ISO |
TRPM2 protein results in increased transport of Calcium TRPM2 protein promotes the reaction [Adenosine Diphosphate Ribose results in increased uptake of Calcium]; TRPM2 protein promotes the reaction [Hydrogen Peroxide results in increased uptake of Calcium] [Clotrimazole results in decreased activity of TRPM2 protein] inhibits the reaction [Mustard Gas results in increased abundance of Calcium]; [Econazole results in decreased activity of TRPM2 protein] inhibits the reaction [Mustard Gas results in increased abundance of Calcium]; TRPM2 protein affects the reaction [Mustard Gas results in increased abundance of Calcium] Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]; Calcium affects the reaction [Hydrogen Peroxide promotes the reaction [TRPM2 protein results in increased transport of Calcium]]; Clotrimazole inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]]; Flufenamic Acid inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]]; Hydrogen Peroxide promotes the reaction [TRPM2 protein results in increased transport of Calcium] |
CTD |
PMID:12529379 PMID:20878536 PMID:21900507 PMID:22036725 |
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NCBI chr21:44,353,621...44,442,644
Ensembl chr21:44,350,163...44,443,081
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G |
TRPM4 |
transient receptor potential cation channel subfamily M member 4 |
multiple interactions increases activity |
ISO EXP |
Calcium binds to and results in increased activity of TRPM4 protein [Ionomycin co-treated with Calcium co-treated with CAMK2D protein] results in increased activity of TRPM4 protein Calcium results in increased activity of TRPM4 protein |
CTD |
PMID:16966582 PMID:17188667 PMID:33392831 |
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NCBI chr19:49,157,792...49,211,836
Ensembl chr19:49,157,741...49,211,836
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G |
TRPM6 |
transient receptor potential cation channel subfamily M member 6 |
multiple interactions |
EXP |
Gadolinium inhibits the reaction [TRPM6 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Calcium]]; Lanthanum inhibits the reaction [TRPM6 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Calcium]]; TRPM6 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Calcium]; TRPM6 protein affects the reaction [1-stearoyl-2-arachidonoylglycerol results in increased transport of Calcium] |
CTD |
PMID:11988098 |
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NCBI chr 9:74,722,495...74,887,921
Ensembl chr 9:74,722,495...74,888,094
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G |
TRPM7 |
transient receptor potential cation channel subfamily M member 7 |
increases abundance decreases abundance multiple interactions |
EXP ISO |
TRPM7 protein results in increased abundance of Calcium TRPM7 gene mutant form results in decreased abundance of Calcium Magnesium inhibits the reaction [TRPM7 protein results in increased abundance of Calcium] |
CTD |
PMID:19515901 PMID:30770447 |
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NCBI chr15:50,557,158...50,686,797
Ensembl chr15:50,552,473...50,686,797
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G |
TRPM8 |
transient receptor potential cation channel subfamily M member 8 |
affects transport multiple interactions increases transport |
ISO EXP |
TRPM8 protein affects the transport of Calcium [icilin binds to and results in increased activity of TRPM8 protein] which affects the abundance of Calcium; [Menthol binds to and results in increased activity of TRPM8 protein] which affects the abundance of Calcium TRPM8 protein results in increased transport of Calcium [icilin results in increased activity of TRPM8 protein] which results in increased transport of Calcium; [Menthol analog binds to and results in increased activity of TRPM8 protein] which results in increased transport of Calcium; [Menthol results in increased activity of TRPM8 protein] which results in increased transport of Calcium; Calcium deficiency inhibits the reaction [Praziquantel results in increased activity of TRPM8 protein]; icilin promotes the reaction [TRPM8 protein results in increased transport of Calcium]; Menthol promotes the reaction [TRPM8 protein results in increased transport of Calcium] |
CTD |
PMID:16174775 PMID:17517434 PMID:18485891 PMID:18524940 PMID:19363131 PMID:23296101 PMID:29054683 More...
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NCBI chr 2:233,917,373...234,019,522
Ensembl chr 2:233,917,373...234,019,522
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G |
TRPV1 |
transient receptor potential cation channel subfamily V member 1 |
affects import multiple interactions increases import |
EXP ISO |
TRPV1 protein affects the import of Calcium 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [anandamide promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [arachidonyl dopamine promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [N-oleoyldopamine promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; [Capsaicin results in increased activity of TRPV1 protein] which results in increased transport of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin results in increased activity of TRPV1] which results in increased uptake of Calcium; [Formaldehyde results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium; Amitriptyline inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Butyrates promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Cadmium inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Calcium affects the reaction [Capsaicin inhibits the reaction [TRPV1 protein affects the susceptibility to Capsaicin]]; Calcium affects the reaction [mustard oil inhibits the reaction [TRPV1 protein affects the susceptibility to Capsaicin]]; capsazepine inhibits the reaction [[Formaldehyde results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]; capsazepine inhibits the reaction [[Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; Cobalt inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Copper inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; HTR2A protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; HTR7 protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; Indomethacin inhibits the reaction [[Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; Lidocaine promotes the reaction [TRPV1 protein results in increased abundance of Calcium]; Masoprocol inhibits the reaction [[Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; Nickel inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Ruthenium Red inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Serotonin promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased transport of Calcium] 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [anandamide promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [arachidonyl dopamine promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [N-oleoyldopamine promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [Protons promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; [arachidonyl dopamine results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [cannabichromene results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [Cannabidiol results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [cannabidiolic acid results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [cannabidivarin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [cannabigerol results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [cannabigerolic acid results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin binds to and results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [Capsaicin binds to TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased import of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin results in increased activity of TRPV1] which results in increased uptake of Calcium; [N-oleoyldopamine results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [nonivamide binds to and results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [resiniferatoxin binds to and results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [resiniferatoxin binds to TRPV1 protein] which results in increased uptake of Calcium; Cannabidiol inhibits the reaction [[Capsaicin binds to TRPV1 protein] which results in increased uptake of Calcium]; Cannabidiol inhibits the reaction [[resiniferatoxin binds to TRPV1 protein] which results in increased uptake of Calcium]; Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]; Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]; capsazepine inhibits the reaction [[Cannabidiol results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; capsazepine inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]]; capsazepine inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; capsazepine inhibits the reaction [Sodium affects the reaction [TRPV1 protein results in increased abundance of Calcium]]; Edetic Acid inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]; iodoresiniferatoxin inhibits the reaction [[N-oleoyldopamine results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; iodoresiniferatoxin inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]]; iodoresiniferatoxin inhibits the reaction [Sodium affects the reaction [TRPV1 protein results in increased abundance of Calcium]]; PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]]; Ruthenium Red inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]]; Ruthenium Red inhibits the reaction [Sodium affects the reaction [TRPV1 protein results in increased abundance of Calcium]]; Sodium affects the reaction [TRPV1 protein results in increased abundance of Calcium]; TRPV1 promotes the reaction [Capsaicin results in increased uptake of Calcium] Sodium affects the reaction [TRPV1 protein results in increased abundance of Calcium]; TRPV1 protein affects the reaction [Capsaicin results in increased abundance of Calcium]; TRPV1 protein affects the reaction [Capsaicin results in increased transport of Calcium] TRPV1 protein results in increased import of Calcium |
CTD |
PMID:11606325 PMID:12569099 PMID:12886029 PMID:15471852 PMID:15615864 PMID:16597917 PMID:16793902 PMID:16901936 PMID:17332266 PMID:17442041 PMID:17508023 PMID:17590514 PMID:17881535 PMID:18172555 PMID:18230619 PMID:18249134 PMID:18331834 PMID:19602228 PMID:19847360 PMID:21453681 PMID:23264033 PMID:28790335 PMID:31096838 More...
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NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411
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G |
TRPV2 |
transient receptor potential cation channel subfamily V member 2 |
multiple interactions |
EXP |
[cannabichromene results in increased activity of TRPV2 protein] which results in increased uptake of Calcium; [Cannabidiol results in increased activity of TRPV2 protein] which results in increased uptake of Calcium; [cannabidiolic acid results in increased activity of TRPV2 protein] which results in increased uptake of Calcium; [cannabidivarin results in increased activity of TRPV2 protein] which results in increased uptake of Calcium |
CTD |
PMID:31096838 |
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NCBI chr17:16,415,571...16,437,003
Ensembl chr17:16,415,571...16,437,003
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G |
TRPV3 |
transient receptor potential cation channel subfamily V member 3 |
multiple interactions |
ISO |
[carvacrol binds to and results in increased activity of TRPV3 protein] which results in increased transport of Calcium; [carvacrol results in increased activity of TRPV3 protein] which results in increased transport of Calcium; [Eugenol binds to and results in increased activity of TRPV3 protein] which results in increased transport of Calcium; Ruthenium Red inhibits the reaction [[carvacrol binds to and results in increased activity of TRPV3 protein] which results in increased transport of Calcium] [carvacrol results in increased activity of TRPV3 protein] which results in increased transport of Calcium; [Eugenol results in increased activity of TRPV3 protein] which results in increased transport of Calcium |
CTD |
PMID:16617338 PMID:20086034 |
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NCBI chr17:3,510,502...3,557,812
Ensembl chr17:3,510,502...3,557,812
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G |
TRPV4 |
transient receptor potential cation channel subfamily V member 4 |
multiple interactions |
EXP ISO |
TRPV4 protein promotes the reaction [phorbol-12,13-didecanoate results in increased import of Calcium] TRPV4 protein promotes the reaction [ITGA2 protein promotes the reaction [[Dinoprostone co-treated with Serotonin] results in increased import of Calcium]] |
CTD |
PMID:18234883 PMID:18355916 |
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NCBI chr12:109,783,087...109,833,398
Ensembl chr12:109,783,087...109,833,406
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G |
TRPV5 |
transient receptor potential cation channel subfamily V member 5 |
increases uptake multiple interactions |
EXP ISO |
TRPV5 protein results in increased uptake of Calcium KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]] |
CTD |
PMID:23747339 |
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NCBI chr 7:142,908,101...142,933,746
Ensembl chr 7:142,908,101...142,933,746
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G |
TRPV6 |
transient receptor potential cation channel subfamily V member 6 |
increases transport multiple interactions increases uptake increases expression |
EXP ISO |
TRPV6 protein results in increased transport of Calcium [[USP2 gene mutant form results in increased expression of NHERF4 protein] which results in increased activity of TRPV6 protein] which results in increased uptake of Calcium TRPV6 protein results in increased uptake of Calcium 4-O-methyl-12-O-tetradecanoylphorbol 13-acetate inhibits the reaction [Tamoxifen inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]]; Cadmium inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]; calphostin C inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]; Gadolinium inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]; Lanthanum inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]; Tamoxifen inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]; TRPV6 protein promotes the reaction [Capsaicin results in increased abundance of Calcium] Calcium deficiency results in increased expression of TRPV6 mRNA |
CTD |
PMID:12584203 PMID:17292493 PMID:18648087 PMID:19996302 PMID:21146870 PMID:26756164 More...
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NCBI chr 7:142,871,208...142,885,745
Ensembl chr 7:142,871,208...142,885,745
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G |
TXN2 |
thioredoxin 2 |
decreases response to substance |
EXP |
TXN2 protein results in decreased susceptibility to Calcium |
CTD |
PMID:18550601 |
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NCBI chr22:36,467,046...36,481,640
Ensembl chr22:36,467,046...36,481,640
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G |
UBB |
ubiquitin B |
affects expression |
ISO |
Calcium affects the expression of UBB mRNA |
CTD |
PMID:15913539 |
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NCBI chr17:16,380,779...16,382,745
Ensembl chr17:16,380,798...16,382,745
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G |
UBE2D2 |
ubiquitin conjugating enzyme E2 D2 |
affects expression |
ISO |
Calcium affects the expression of UBE2D2 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 5:139,526,240...139,628,434
Ensembl chr 5:139,526,431...139,628,434
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G |
UBE2G1 |
ubiquitin conjugating enzyme E2 G1 |
affects expression multiple interactions |
ISO |
Calcium affects the expression of UBE2G1 mRNA [Calcium co-treated with Calcitriol] affects the expression of UBE2G1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr17:4,269,259...4,366,675
Ensembl chr17:4,269,259...4,366,675
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G |
UBE2I |
ubiquitin conjugating enzyme E2 I |
affects expression |
ISO |
Calcium affects the expression of UBE2I mRNA |
CTD |
PMID:15913539 |
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NCBI chr16:1,309,152...1,327,017
Ensembl chr16:1,291,444...1,327,018
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G |
UBTF |
upstream binding transcription factor |
affects expression |
ISO |
Calcium affects the expression of UBTF mRNA alternative form |
CTD |
PMID:15913539 |
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NCBI chr17:44,205,040...44,221,304
Ensembl chr17:44,205,033...44,221,626
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G |
UCN |
urocortin |
multiple interactions |
ISO |
astressin inhibits the reaction [UCN protein inhibits the reaction [Thapsigargin results in increased uptake of Calcium]]; UCN protein inhibits the reaction [Thapsigargin results in increased uptake of Calcium] |
CTD |
PMID:17885217 |
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NCBI chr 2:27,307,400...27,308,445
Ensembl chr 2:27,307,400...27,308,445
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G |
UMOD |
uromodulin |
affects binding |
EXP |
UMOD protein binds to Calcium |
CTD |
PMID:35263610 |
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NCBI chr16:20,333,051...20,356,301
Ensembl chr16:20,333,051...20,356,301
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G |
USP15 |
ubiquitin specific peptidase 15 |
multiple interactions |
EXP |
Calcium affects the reaction [Morphine results in increased expression of USP15 mRNA] |
CTD |
PMID:24068670 |
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NCBI chr12:62,260,404...62,416,389
Ensembl chr12:62,260,338...62,417,431
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G |
USP2 |
ubiquitin specific peptidase 2 |
multiple interactions |
ISO |
[[USP2 gene mutant form results in increased expression of NHERF4 protein] which results in increased activity of TRPV6 protein] which results in increased uptake of Calcium |
CTD |
PMID:26756164 |
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NCBI chr11:119,355,215...119,381,690
Ensembl chr11:119,355,215...119,381,711
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G |
VDAC1 |
voltage dependent anion channel 1 |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of VDAC1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975
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G |
VDR |
vitamin D receptor |
affects metabolic processing affects abundance affects expression affects response to substance |
EXP ISO |
VDR gene polymorphism affects the metabolism of Calcium VDR protein affects the abundance of Calcium Calcium affects the expression of VDR mRNA VDR gene polymorphism affects the susceptibility to Calcium |
CTD |
PMID:11500311 PMID:15861036 PMID:15883634 PMID:15913539 PMID:16048257 |
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NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048
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G |
VEGFA |
vascular endothelial growth factor A |
affects expression increases abundance multiple interactions |
ISO EXP |
Calcium affects the expression of VEGFA mRNA VEGFA protein results in increased abundance of Calcium [VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium; TRPC6 protein promotes the reaction [[VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium]; VEGFA protein promotes the reaction [[Diglycerides results in increased activity of TRPC6 protein] which results in increased abundance of Calcium] |
CTD |
PMID:14551041 PMID:15913539 PMID:30524369 |
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NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
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G |
VIM |
vimentin |
multiple interactions |
ISO |
Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of VIM protein] |
CTD |
PMID:21879721 |
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NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593
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G |
VIP |
vasoactive intestinal peptide |
decreases abundance |
ISO |
VIP protein results in decreased abundance of Calcium |
CTD |
PMID:21039959 |
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NCBI chr 6:152,750,797...152,759,760
Ensembl chr 6:152,750,797...152,759,765
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G |
WNT5A |
Wnt family member 5A |
increases secretion multiple interactions increases expression |
EXP |
Calcium results in increased secretion of WNT5A protein CASR mutant form inhibits the reaction [Calcium results in increased expression of WNT5A protein]; WNT5A protein promotes the reaction [Calcium results in increased expression of KRT1 mRNA]; WNT5A protein promotes the reaction [Calcium results in increased expression of KRT1 protein]; WNT5A protein promotes the reaction [Calcium results in increased expression of LORICRIN mRNA]; WNT5A protein promotes the reaction [Calcium results in increased expression of LORICRIN protein] Calcium results in increased expression of WNT5A mRNA |
CTD |
PMID:24658506 |
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NCBI chr 3:55,465,715...55,505,263
Ensembl chr 3:55,465,715...55,490,539
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G |
YWHAZ |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta |
affects expression |
ISO |
Calcium affects the expression of YWHAZ mRNA |
CTD |
PMID:15913539 |
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NCBI chr 8:100,916,523...100,953,382
Ensembl chr 8:100,916,523...100,953,388
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G |
ABCA1 |
ATP binding cassette subfamily A member 1 |
increases expression multiple interactions decreases expression |
ISO EXP |
Atorvastatin results in increased expression of ABCA1 mRNA [Rosiglitazone co-treated with Atorvastatin] results in increased expression of ABCA1 protein Atorvastatin results in decreased expression of ABCA1 mRNA; Atorvastatin results in decreased expression of ABCA1 protein |
CTD |
PMID:15183127 PMID:16386711 PMID:25278499 |
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NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155
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G |
ABCB1 |
ATP binding cassette subfamily B member 1 |
multiple interactions decreases expression decreases activity increases transport |
EXP ISO |
ABCB1 alternative form affects the reaction [CYP3A4 polymorphism affects the susceptibility to Atorvastatin]; Atorvastatin analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM] Atorvastatin results in decreased expression of ABCB1A mRNA Atorvastatin analog results in decreased activity of ABCB1 protein ABCB1 protein results in increased transport of Atorvastatin; ABCB1 protein results in increased transport of Atorvastatin analog |
CTD |
PMID:10751037 PMID:15616150 PMID:19802823 PMID:24502637 |
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NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
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G |
ABCB11 |
ATP binding cassette subfamily B member 11 |
multiple interactions decreases activity |
EXP |
Atorvastatin inhibits the reaction [ABCB11 protein affects the import of Taurocholic Acid]; Atorvastatin inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid] Atorvastatin results in decreased activity of ABCB11 protein |
CTD |
PMID:15901796 PMID:23956101 PMID:24014644 |
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NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324
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G |
ABCB4 |
ATP binding cassette subfamily B member 4 |
increases expression |
ISO |
Atorvastatin results in increased expression of ABCB4 mRNA; Atorvastatin results in increased expression of ABCB4 protein |
CTD |
PMID:15986414 PMID:25278499 |
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NCBI chr 7:87,365,896...87,476,027
Ensembl chr 7:87,401,696...87,480,435
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G |
ABCC2 |
ATP binding cassette subfamily C member 2 |
decreases activity multiple interactions increases expression |
EXP ISO |
Atorvastatin analog results in decreased activity of ABCC2 protein ABCC2 protein binds to and results in increased uptake of Atorvastatin analog; Atorvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Atorvastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM] Atorvastatin results in increased expression of ABCC2 mRNA |
CTD |
PMID:15616150 PMID:23562342 PMID:25278499 |
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NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
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G |
ABCC3 |
ATP binding cassette subfamily C member 3 |
increases expression |
ISO |
Atorvastatin results in increased expression of ABCC3 mRNA; Atorvastatin results in increased expression of ABCC3 protein |
CTD |
PMID:15986414 |
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NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253
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G |
ABCG2 |
ATP binding cassette subfamily G member 2 (JR blood group) |
increases expression |
ISO |
Atorvastatin results in increased expression of ABCG2 mRNA |
CTD |
PMID:25278499 |
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NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
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G |
ABCG5 |
ATP binding cassette subfamily G member 5 |
increases expression |
ISO |
Atorvastatin results in increased expression of ABCG5 mRNA |
CTD |
PMID:25278499 |
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NCBI chr 2:43,806,211...43,839,231
Ensembl chr 2:43,812,472...43,838,865
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G |
ABCG8 |
ATP binding cassette subfamily G member 8 |
increases expression |
ISO |
Atorvastatin results in increased expression of ABCG8 mRNA |
CTD |
PMID:25278499 |
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NCBI chr 2:43,838,971...43,882,988
Ensembl chr 2:43,831,942...43,882,988
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G |
ACACB |
acetyl-CoA carboxylase beta |
increases expression multiple interactions |
ISO |
Atorvastatin results in increased expression of ACACB mRNA Mevalonic Acid inhibits the reaction [Atorvastatin results in increased expression of ACACB mRNA] |
CTD |
PMID:12056585 |
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NCBI chr12:109,111,189...109,268,226
Ensembl chr12:109,116,587...109,268,226
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G |
ACE |
angiotensin I converting enzyme |
decreases expression |
ISO |
Atorvastatin results in decreased expression of ACE mRNA |
CTD |
PMID:23390189 |
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NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
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G |
ACE2 |
angiotensin converting enzyme 2 |
increases expression |
ISO |
Atorvastatin results in increased expression of ACE2 mRNA |
CTD |
PMID:23390189 |
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NCBI chr X:15,518,197...15,607,211
Ensembl chr X:15,494,566...15,607,236
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G |
ACOX1 |
acyl-CoA oxidase 1 |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [Fructose results in decreased expression of ACOX1 mRNA] |
CTD |
PMID:21122807 |
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NCBI chr17:75,941,507...75,979,166
Ensembl chr17:75,941,507...75,979,177
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G |
ACTA2 |
actin alpha 2, smooth muscle |
multiple interactions |
ISO |
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of ACTA2 protein] |
CTD |
PMID:34939712 |
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NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,935,074...88,991,339
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G |
ADAM12 |
ADAM metallopeptidase domain 12 |
decreases expression |
ISO |
Atorvastatin results in decreased expression of ADAM12 protein |
CTD |
PMID:18360054 |
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NCBI chr10:126,012,391...126,388,477
Ensembl chr10:126,012,381...126,388,477
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G |
ADAM17 |
ADAM metallopeptidase domain 17 |
decreases expression |
ISO |
Atorvastatin results in decreased expression of ADAM17 protein |
CTD |
PMID:18360054 |
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NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732
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G |
ADGRE1 |
adhesion G protein-coupled receptor E1 |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ADGRE1 protein] |
CTD |
PMID:37023836 |
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NCBI chr19:6,887,579...6,940,450
Ensembl chr19:6,887,566...6,940,459
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G |
ADIPOQ |
adiponectin, C1Q and collagen domain containing |
decreases expression increases expression |
EXP |
Atorvastatin results in decreased expression of ADIPOQ protein Atorvastatin results in increased expression of ADIPOQ protein |
CTD |
PMID:19651449 |
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NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
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G |
AGT |
angiotensinogen |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [AGT protein results in decreased expression of SOD1 protein]; Atorvastatin inhibits the reaction [AGT protein results in increased abundance of Malondialdehyde]; Atorvastatin inhibits the reaction [AGT protein results in increased activity of MAPK1 protein]; Atorvastatin inhibits the reaction [AGT protein results in increased activity of MAPK3 protein]; Atorvastatin inhibits the reaction [AGT protein results in increased expression of NOX1 protein] |
CTD |
PMID:19451411 |
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NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
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G |
AKT1 |
AKT serine/threonine kinase 1 |
multiple interactions increases phosphorylation decreases phosphorylation |
ISO EXP |
Atorvastatin inhibits the reaction [Homocysteine results in decreased phosphorylation of AKT1 protein] [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of AKT1 protein]; coenzyme Q10 inhibits the reaction [Atorvastatin results in decreased phosphorylation of AKT1 protein] Atorvastatin results in increased phosphorylation of AKT1 protein [Atorvastatin co-treated with Celecoxib] results in decreased phosphorylation of AKT1 protein; Atorvastatin results in decreased expression of and results in decreased phosphorylation of AKT1 protein |
CTD |
PMID:18172863 PMID:19526287 PMID:20305681 PMID:27345130 PMID:27815113 PMID:29630879 PMID:32259528 More...
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NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
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G |
ANGPT2 |
angiopoietin 2 |
increases expression |
EXP |
Atorvastatin results in increased expression of ANGPT2 mRNA |
CTD |
PMID:16410222 |
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NCBI chr 8:6,499,632...6,563,245
Ensembl chr 8:6,499,632...6,563,409
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G |
APOB |
apolipoprotein B |
multiple interactions decreases secretion decreases expression |
EXP ISO |
Atorvastatin results in decreased expression of and results in decreased secretion of APOB protein Atorvastatin inhibits the reaction [Fructose results in increased expression of APOB protein] Atorvastatin results in decreased secretion of APOB protein Atorvastatin results in decreased expression of APOB protein |
CTD |
PMID:9512650 PMID:10357840 PMID:11728391 PMID:12065722 PMID:12172771 PMID:12612140 PMID:12633795 PMID:18702965 More...
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NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073
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G |
APOE |
apolipoprotein E |
decreases expression multiple interactions |
EXP ISO |
Atorvastatin results in decreased expression of APOE mRNA; Atorvastatin results in decreased expression of APOE protein Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the activity of GPT protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of BAX protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of BCL2 protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of CASP3 protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of FTH1 protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of GPX4 protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of HMOX1 protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of NFE2L2 protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of RELA protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of TFRC protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of TRP53 protein] [Bezafibrate co-treated with Enalapril co-treated with Dipyridamole co-treated with Atorvastatin co-treated with Valsartan] results in decreased expression of APOE protein |
CTD |
PMID:16386711 PMID:19603250 PMID:32976958 PMID:37121058 |
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NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
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G |
APP |
amyloid beta precursor protein |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [APP protein results in decreased expression of SLC1A2 protein]; Atorvastatin inhibits the reaction [APP protein results in decreased expression of SLC1A3 protein] |
CTD |
PMID:20816828 |
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NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128
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G |
ATF6 |
activating transcription factor 6 |
multiple interactions |
ISO |
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein] |
CTD |
PMID:34939712 |
|
NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574
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G |
ATG5 |
autophagy related 5 |
multiple interactions increases response to substance |
ISO |
ATG5 mutant form promotes the reaction [Atorvastatin results in increased cleavage of CASP3 protein]; ATG5 mutant form promotes the reaction [Atorvastatin results in increased cleavage of PARP1 protein] ATG5 results in increased susceptibility to Atorvastatin |
CTD |
PMID:20876807 |
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NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791
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G |
BAK1 |
BCL2 antagonist/killer 1 |
increases expression |
EXP |
Atorvastatin results in increased expression of BAK1 protein |
CTD |
PMID:19935899 |
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NCBI chr 6:33,572,552...33,580,276
Ensembl chr 6:33,572,547...33,580,293
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G |
BAX |
BCL2 associated X, apoptosis regulator |
increases expression multiple interactions |
EXP ISO |
Atorvastatin results in increased expression of BAX protein Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of BAX protein] |
CTD |
PMID:19935899 PMID:37121058 |
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NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
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G |
BCL2 |
BCL2 apoptosis regulator |
decreases expression multiple interactions |
EXP ISO |
Atorvastatin results in decreased expression of BCL2 mRNA; Atorvastatin results in decreased expression of BCL2 protein Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of BCL2 protein] [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of BCL2 protein] 2-tert-butylhydroquinone inhibits the reaction [Atorvastatin results in decreased expression of BCL2 protein]; RHOA mutant form inhibits the reaction [Atorvastatin results in decreased expression of BCL2 protein] |
CTD |
PMID:16470222 PMID:31423616 PMID:32259528 PMID:37121058 |
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NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
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G |
BECN1 |
beclin 1 |
increases expression |
ISO |
Atorvastatin results in increased expression of BECN1 protein |
CTD |
PMID:20876807 |
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NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
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G |
BGLAP |
bone gamma-carboxyglutamate protein |
increases expression |
EXP |
Atorvastatin results in increased expression of BGLAP mRNA |
CTD |
PMID:17252541 |
|
NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
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G |
BID |
BH3 interacting domain death agonist |
multiple interactions |
ISO |
Atorvastatin results in decreased expression of and results in increased cleavage of BID protein; Mevalonic Acid inhibits the reaction [Atorvastatin results in decreased expression of and results in increased cleavage of BID protein]; U 0126 inhibits the reaction [Atorvastatin results in decreased expression of and results in increased cleavage of BID protein] |
CTD |
PMID:18339080 |
|
NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770
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G |
BIRC5 |
baculoviral IAP repeat containing 5 |
decreases expression |
ISO |
Atorvastatin results in decreased expression of BIRC5 mRNA; Atorvastatin results in decreased expression of BIRC5 protein |
CTD |
PMID:17372815 |
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NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
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G |
BMP2 |
bone morphogenetic protein 2 |
increases expression increases secretion |
EXP |
Atorvastatin results in increased expression of BMP2 mRNA Atorvastatin results in increased secretion of BMP2 protein |
CTD |
PMID:16470222 PMID:17252541 |
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NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246
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G |
C3 |
complement C3 |
multiple interactions |
ISO |
[Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased activity of C3 protein modified form] |
CTD |
PMID:20946910 |
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NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
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G |
CASP1 |
caspase 1 |
multiple interactions |
ISO |
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CASP1 protein] |
CTD |
PMID:34939712 |
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NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
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G |
CASP3 |
caspase 3 |
multiple interactions decreases activity increases activity increases cleavage |
EXP ISO |
2-tert-butylhydroquinone inhibits the reaction [Atorvastatin results in increased cleavage of CASP3 protein]; [Atorvastatin co-treated with Celecoxib] results in increased cleavage of and results in increased activity of CASP3 protein; bafilomycin A1 promotes the reaction [Atorvastatin results in increased cleavage of CASP3 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin results in increased activity of CASP3 protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased activity of CASP3 protein]; RHOA protein inhibits the reaction [Atorvastatin results in increased activity of CASP3 protein] Atorvastatin results in decreased activity of CASP3 protein [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased activity of CASP3 protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased activity of CASP3 protein]; U 0126 inhibits the reaction [Atorvastatin results in increased activity of CASP3 protein] [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the cleavage of CASP3 protein; ATG5 mutant form promotes the reaction [Atorvastatin results in increased cleavage of CASP3 protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of CASP3 protein]; Atorvastatin inhibits the reaction [Homocysteine results in increased activity of CASP3 protein] |
CTD |
PMID:16470222 PMID:18172863 PMID:18339080 PMID:19429019 PMID:20305681 PMID:20876807 PMID:20946910 PMID:30511338 PMID:31423616 PMID:37121058 More...
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NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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G |
CASP8 |
caspase 8 |
multiple interactions increases activity |
EXP ISO |
[Atorvastatin co-treated with Celecoxib] results in increased cleavage of CASP8 protein [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased activity of CASP8 protein]; [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased expression of CASP8 protein] Atorvastatin results in increased activity of CASP8 protein |
CTD |
PMID:15705602 PMID:18172863 PMID:20946910 |
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NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
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G |
CASP9 |
caspase 9 |
multiple interactions increases activity |
EXP ISO |
[Atorvastatin co-treated with Celecoxib] results in increased cleavage of CASP9 protein Mevalonic Acid inhibits the reaction [Atorvastatin results in increased activity of CASP9 protein]; U 0126 inhibits the reaction [Atorvastatin results in increased activity of CASP9 protein] |
CTD |
PMID:15705602 PMID:16470222 PMID:18172863 PMID:18339080 PMID:29630879 |
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NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
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G |
CAT |
catalase |
multiple interactions increases activity |
ISO EXP |
Atorvastatin inhibits the reaction [sodium arsenite results in decreased activity of CAT protein] Atorvastatin results in increased activity of CAT protein |
CTD |
PMID:17479860 PMID:25218292 |
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NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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G |
CCL2 |
C-C motif chemokine ligand 2 |
multiple interactions decreases expression |
EXP ISO |
Atorvastatin inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Atorvastatin results in decreased expression of and results in decreased secretion of CCL2 protein; Mevalonic Acid inhibits the reaction [Atorvastatin inhibits the reaction [TNF results in increased expression of CCL2 mRNA]]; Mevalonic Acid inhibits the reaction [Atorvastatin results in decreased expression of CCL2 mRNA] [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CCL2 protein]; Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of CCL2 protein] |
CTD |
PMID:12117737 PMID:25058445 PMID:34939712 |
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NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
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G |
CD14 |
CD14 molecule |
decreases expression |
EXP |
Atorvastatin results in decreased expression of CD14 protein |
CTD |
PMID:18333374 |
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NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700
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G |
CD36 |
CD36 molecule (CD36 blood group) |
multiple interactions |
EXP ISO |
Atorvastatin inhibits the reaction [Rosiglitazone results in increased expression of CD36 mRNA]; Atorvastatin inhibits the reaction [Rosiglitazone results in increased expression of CD36 protein] [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of CD36 protein] |
CTD |
PMID:15183127 PMID:16386711 PMID:32259528 |
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NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277
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G |
CD40 |
CD40 molecule |
decreases expression |
EXP |
Atorvastatin results in decreased expression of CD40 protein |
CTD |
PMID:16387846 |
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NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863
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G |
CD40LG |
CD40 ligand |
decreases expression |
EXP |
Atorvastatin results in decreased expression of CD40LG protein |
CTD |
PMID:16368305 PMID:19171469 |
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NCBI chr X:136,648,158...136,660,390
Ensembl chr X:136,648,158...136,660,390
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G |
CD83 |
CD83 molecule |
decreases expression |
EXP |
Atorvastatin results in decreased expression of CD83 protein |
CTD |
PMID:16387846 |
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NCBI chr 6:14,117,256...14,136,918
Ensembl chr 6:14,117,256...14,136,918
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G |
CD86 |
CD86 molecule |
decreases expression |
EXP |
Atorvastatin results in decreased expression of CD86 protein |
CTD |
PMID:16387846 |
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NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
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G |
CDC42 |
cell division cycle 42 |
multiple interactions |
EXP |
[Poly I-C co-treated with Atorvastatin] results in decreased expression of CDC42 mRNA |
CTD |
PMID:34696514 |
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NCBI chr 1:22,052,709...22,101,360
Ensembl chr 1:22,052,627...22,101,360
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G |
CDH1 |
cadherin 1 |
multiple interactions |
ISO |
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of CDH1 protein] |
CTD |
PMID:34939712 |
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NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
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G |
CDKN1A |
cyclin dependent kinase inhibitor 1A |
multiple interactions increases expression |
EXP |
[Atorvastatin co-treated with Celecoxib] results in increased expression of CDKN1A protein; CDKN1A protein mutant form inhibits the reaction [Atorvastatin results in increased cleavage of PARP1 protein] Atorvastatin results in increased expression of CDKN1A protein |
CTD |
PMID:18172863 PMID:20876807 |
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NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
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G |
CDKN1B |
cyclin dependent kinase inhibitor 1B |
multiple interactions increases expression |
EXP |
[Atorvastatin co-treated with Celecoxib] results in increased expression of CDKN1B protein Atorvastatin results in increased expression of CDKN1B protein |
CTD |
PMID:16470222 PMID:18172863 |
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NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369
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G |
CHUK |
component of inhibitor of nuclear factor kappa B kinase complex |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [Sodium Glutamate results in increased phosphorylation of CHUK protein] |
CTD |
PMID:19800637 |
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NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596
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G |
CLCN1 |
chloride voltage-gated channel 1 |
decreases expression |
ISO |
Atorvastatin results in decreased expression of CLCN1 protein |
CTD |
PMID:27377005 |
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NCBI chr 7:143,316,111...143,352,083
Ensembl chr 7:143,316,111...143,352,083
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G |
COL1A1 |
collagen type I alpha 1 chain |
increases expression |
EXP |
Atorvastatin results in increased expression of COL1A1 mRNA |
CTD |
PMID:17252541 |
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NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
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G |
CPT1A |
carnitine palmitoyltransferase 1A |
increases expression multiple interactions |
ISO |
Atorvastatin results in increased expression of CPT1A mRNA N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Atorvastatin results in increased expression of CPT1A mRNA] |
CTD |
PMID:19053045 |
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NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410
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G |
CRP |
C-reactive protein |
multiple interactions decreases expression |
EXP ISO |
[Atorvastatin co-treated with Amlodipine] results in decreased expression of CRP protein; Atorvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of CRP mRNA]; Atorvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of CRP protein] Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of CRP protein] Atorvastatin results in decreased expression of CRP protein |
CTD |
PMID:16025360 PMID:16360360 PMID:17673219 PMID:18389332 PMID:21584495 PMID:25058445 More...
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NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
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G |
CS |
citrate synthase |
increases expression multiple interactions |
ISO |
Atorvastatin results in increased expression of CS mRNA Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of CS mRNA] |
CTD |
PMID:21775390 |
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NCBI chr12:56,271,699...56,300,330
Ensembl chr12:56,271,699...56,300,391
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G |
CSF2 |
colony stimulating factor 2 |
multiple interactions |
EXP |
Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of CSF2 mRNA]; Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of CSF2 protein]; Atorvastatin inhibits the reaction [Particulate Matter results in increased expression of CSF2 mRNA]; Atorvastatin inhibits the reaction [Particulate Matter results in increased expression of CSF2 protein] |
CTD |
PMID:19482827 |
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NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170
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G |
CXCL10 |
C-X-C motif chemokine ligand 10 |
decreases expression |
ISO |
Atorvastatin results in decreased expression of CXCL10 |
CTD |
PMID:15831368 |
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NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
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G |
CXCL8 |
C-X-C motif chemokine ligand 8 |
multiple interactions increases expression decreases secretion decreases expression |
EXP |
Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of CXCL8 mRNA]; Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of CXCL8 protein]; Atorvastatin inhibits the reaction [Particulate Matter results in increased expression of CXCL8 mRNA]; Atorvastatin inhibits the reaction [Particulate Matter results in increased expression of CXCL8 protein]; Atorvastatin inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]; Atorvastatin promotes the reaction [Lipopolysaccharides results in increased secretion of CXCL8 protein]; Atorvastatin results in decreased expression of and results in decreased secretion of CXCL8 protein; Mevalonic Acid inhibits the reaction [Atorvastatin inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]]; Mevalonic Acid inhibits the reaction [Atorvastatin results in decreased expression of CXCL8 mRNA] Atorvastatin results in increased expression of CXCL8 protein Atorvastatin results in decreased secretion of CXCL8 protein Atorvastatin results in decreased expression of CXCL8 mRNA; Atorvastatin results in decreased expression of CXCL8 protein |
CTD |
PMID:12117737 PMID:16387846 PMID:16410222 PMID:19171469 PMID:19482827 |
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NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
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G |
CYBA |
cytochrome b-245 alpha chain |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of CYBA mRNA] |
CTD |
PMID:25218292 |
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NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083
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G |
CYCS |
cytochrome c, somatic |
multiple interactions affects localization |
ISO EXP |
[Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of CYCS protein] 2-tert-butylhydroquinone inhibits the reaction [Atorvastatin affects the localization of CYCS protein] |
CTD |
PMID:31423616 PMID:32259528 |
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NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
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G |
CYP11A1 |
cytochrome P450 family 11 subfamily A member 1 |
affects expression |
ISO |
Atorvastatin affects the expression of CYP11A1 mRNA |
CTD |
PMID:29574565 |
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NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646
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G |
CYP17A1 |
cytochrome P450 family 17 subfamily A member 1 |
increases expression |
ISO |
Atorvastatin results in increased expression of CYP17A1 mRNA |
CTD |
PMID:29574565 |
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NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472
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G |
CYP19A1 |
cytochrome P450 family 19 subfamily A member 1 |
increases expression |
ISO |
Atorvastatin results in increased expression of CYP19A1 mRNA |
CTD |
PMID:29574565 |
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NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601
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G |
CYP21A1P |
cytochrome P450 family 21 subfamily A member 1, pseudogene |
increases expression |
ISO |
Atorvastatin results in increased expression of CYP21A2 mRNA |
CTD |
PMID:29574565 |
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NCBI chr 6:32,005,636...32,008,909
Ensembl chr 6:32,005,689...32,008,399
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G |
CYP27A1 |
cytochrome P450 family 27 subfamily A member 1 |
decreases expression increases expression |
EXP ISO |
Atorvastatin results in decreased expression of CYP27A1 mRNA; Atorvastatin results in decreased expression of CYP27A1 protein Atorvastatin results in increased expression of CYP27A1 mRNA |
CTD |
PMID:16386711 PMID:25278499 |
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NCBI chr 2:218,782,147...218,815,293
Ensembl chr 2:218,781,749...218,815,293
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G |
CYP2B6 |
cytochrome P450 family 2 subfamily B member 6 |
increases expression |
EXP ISO |
Atorvastatin results in increased expression of CYP2B6 mRNA Atorvastatin results in increased expression of CYP2B10 mRNA; Atorvastatin results in increased expression of CYP2B10 protein |
CTD |
PMID:15802384 PMID:15986414 |
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NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
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G |
CYP39A1 |
cytochrome P450 family 39 subfamily A member 1 |
increases expression |
ISO |
Atorvastatin results in increased expression of CYP39A1 mRNA |
CTD |
PMID:25278499 |
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NCBI chr 6:46,549,580...46,652,818
Ensembl chr 6:46,549,580...46,652,830
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G |
CYP3A4 |
cytochrome P450 family 3 subfamily A member 4 |
increases expression multiple interactions decreases expression decreases activity affects metabolic processing affects response to substance increases metabolic processing |
EXP ISO |
Atorvastatin results in increased expression of CYP3A4 protein Atorvastatin promotes the reaction [Berberine results in decreased activity of CYP3A4 protein]; Berberine promotes the reaction [Atorvastatin results in decreased activity of CYP3A4 protein]; Berberine promotes the reaction [Atorvastatin results in decreased expression of CYP3A4 mRNA]; Berberine promotes the reaction [Atorvastatin results in decreased expression of CYP3A4 protein] Atorvastatin results in decreased expression of CYP3A4 mRNA; Atorvastatin results in decreased expression of CYP3A4 protein CYP3A4 protein affects the metabolism of Atorvastatin CYP3A4 polymorphism affects the susceptibility to Atorvastatin CYP3A4 protein results in increased metabolism of Atorvastatin ABCB1 alternative form affects the reaction [CYP3A4 polymorphism affects the susceptibility to Atorvastatin]; Atorvastatin inhibits the reaction [CYP3A4 protein affects the metabolism of Midazolam] |
CTD |
PMID:15963098 PMID:16011971 PMID:16029222 PMID:18528690 PMID:18846481 PMID:19802823 PMID:26616219 PMID:30086269 More...
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NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
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G |
CYP3A51P |
cytochrome P450 family 3 subfamily A member 51, pseudogene |
affects response to substance |
EXP |
CYP3A51P gene polymorphism affects the susceptibility to Atorvastatin |
CTD |
PMID:20519697 |
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NCBI chr 7:99,685,024...99,700,120
Ensembl chr 7:99,685,145...99,700,034
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G |
CYP7A1 |
cytochrome P450 family 7 subfamily A member 1 |
increases expression multiple interactions |
ISO |
Atorvastatin results in increased expression of CYP7A1 mRNA Atorvastatin inhibits the reaction [Dietary Fats results in decreased expression of CYP7A1 mRNA] |
CTD |
PMID:25278499 PMID:32048413 |
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NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163
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G |
CYP7B1 |
cytochrome P450 family 7 subfamily B member 1 |
decreases expression |
ISO |
Atorvastatin results in decreased expression of CYP7B1 mRNA |
CTD |
PMID:25278499 |
|
NCBI chr 8:64,586,575...64,798,737
Ensembl chr 8:64,587,763...64,798,737
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G |
DCX |
doublecortin |
increases expression |
ISO |
Atorvastatin results in increased expression of DCX protein |
CTD |
PMID:15255259 |
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NCBI chr X:111,293,779...111,412,192
Ensembl chr X:111,293,779...111,412,429
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G |
DGAT1 |
diacylglycerol O-acyltransferase 1 |
increases expression multiple interactions increases activity |
ISO |
Atorvastatin results in increased expression of DGAT1 mRNA Mevalonic Acid inhibits the reaction [Atorvastatin results in increased activity of DGAT1 protein] |
CTD |
PMID:12056585 |
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NCBI chr 8:144,314,584...144,326,852
Ensembl chr 8:144,314,584...144,326,910
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G |
DSCC1 |
DNA replication and sister chromatid cohesion 1 |
affects response to substance |
EXP |
DSCC1 protein affects the susceptibility to Atorvastatin |
CTD |
PMID:35926565 |
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NCBI chr 8:119,833,976...119,855,894
Ensembl chr 8:119,833,976...119,855,894
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G |
EDN1 |
endothelin 1 |
decreases expression |
EXP |
Atorvastatin results in decreased expression of EDN1 protein |
CTD |
PMID:16360360 |
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NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194
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G |
EDNRA |
endothelin receptor type A |
multiple interactions decreases expression |
ISO |
Atorvastatin promotes the reaction [Losartan results in decreased expression of EDNRA mRNA]; Losartan promotes the reaction [Atorvastatin results in decreased expression of EDNRA mRNA] |
CTD |
PMID:23091284 |
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NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954
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G |
EGFR |
epidermal growth factor receptor |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [Phenylephrine results in increased expression of and results in increased phosphorylation of and results in increased activity of EGFR protein] |
CTD |
PMID:18360054 |
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NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
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G |
EIF2AK3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions increases response to substance |
EXP |
EIF2AK3 mutant form inhibits the reaction [Atorvastatin results in increased phosphorylation of EIF2S1 protein] EIF2AK3 results in increased susceptibility to Atorvastatin |
CTD |
PMID:20876807 |
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NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518
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G |
EIF2S1 |
eukaryotic translation initiation factor 2 subunit alpha |
multiple interactions increases phosphorylation |
EXP |
4-phenylbutyric acid inhibits the reaction [Atorvastatin results in increased phosphorylation of EIF2S1 protein]; EIF2AK3 mutant form inhibits the reaction [Atorvastatin results in increased phosphorylation of EIF2S1 protein] |
CTD |
PMID:20876807 |
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NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516
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G |
EPB41 |
erythrocyte membrane protein band 4.1 |
multiple interactions |
ISO |
[Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in decreased expression of EPB41 protein] |
CTD |
PMID:20946910 |
|
NCBI chr 1:28,887,100...29,120,041
Ensembl chr 1:28,887,091...29,120,046
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G |
F2 |
coagulation factor II, thrombin |
decreases activity |
EXP |
Atorvastatin results in decreased activity of F2 protein |
CTD |
PMID:16907931 |
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NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
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G |
F5 |
coagulation factor V |
decreases activity |
EXP |
Atorvastatin results in decreased activity of F5 protein |
CTD |
PMID:16907931 |
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NCBI chr 1:169,511,951...169,586,481
Ensembl chr 1:169,511,951...169,586,588
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G |
FADD |
Fas associated via death domain |
multiple interactions |
ISO |
[Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased expression of FADD protein] |
CTD |
PMID:20946910 |
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NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,296...70,207,390
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G |
FAS |
Fas cell surface death receptor |
affects expression |
ISO |
Atorvastatin affects the expression of FAS mRNA; Atorvastatin affects the expression of FAS protein |
CTD |
PMID:17372815 |
|
NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
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G |
FASLG |
Fas ligand |
multiple interactions increases expression |
ISO EXP |
[Atorvastatin co-treated with Acetylcysteine] inhibits the reaction [sodium arsenite results in increased expression of FASLG protein] Atorvastatin results in increased expression of FASLG protein modified form Atorvastatin inhibits the reaction [TNF protein results in decreased expression of and results in decreased secretion of FASLG protein modified form] |
CTD |
PMID:15063428 PMID:20946910 |
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NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
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G |
FASN |
fatty acid synthase |
increases expression multiple interactions |
EXP ISO |
Atorvastatin results in increased expression of FASN mRNA [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of FASN protein]; Atorvastatin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of FASN protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased expression of FASN mRNA] |
CTD |
PMID:11728391 PMID:12056585 PMID:32259528 |
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NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
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G |
FBXO32 |
F-box protein 32 |
increases expression |
ISO |
Atorvastatin results in increased expression of FBXO32 mRNA |
CTD |
PMID:27377005 |
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NCBI chr 8:123,497,889...123,541,206
Ensembl chr 8:123,497,889...123,541,206
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G |
FGF19 |
fibroblast growth factor 19 |
decreases expression |
ISO |
Atorvastatin results in decreased expression of FGF15 mRNA |
CTD |
PMID:25278499 |
|
NCBI chr11:69,698,238...69,704,022
Ensembl chr11:69,698,238...69,704,022
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G |
FOXO1 |
forkhead box O1 |
decreases phosphorylation |
ISO |
Atorvastatin results in decreased phosphorylation of FOXO1 protein |
CTD |
PMID:33034787 |
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NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641
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G |
FTH1 |
ferritin heavy chain 1 |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of FTH1 protein] |
CTD |
PMID:32976958 |
|
NCBI chr11:61,964,285...61,967,634
Ensembl chr11:61,959,718...61,967,634
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G |
G6PC1 |
glucose-6-phosphatase catalytic subunit 1 |
multiple interactions |
EXP |
[Atorvastatin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA |
CTD |
PMID:24204015 |
|
NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438
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G |
GCK |
glucokinase |
decreases expression multiple interactions |
EXP ISO |
Atorvastatin results in decreased expression of GCK protein NR1I2 protein promotes the reaction [Atorvastatin results in decreased expression of GCK protein] |
CTD |
PMID:26616219 |
|
NCBI chr 7:44,143,213...44,189,439
Ensembl chr 7:44,143,213...44,198,170
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G |
GJA1 |
gap junction protein alpha 1 |
multiple interactions |
ISO |
Atorvastatin promotes the reaction [dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of GJA1 protein]] |
CTD |
PMID:34939712 |
|
NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
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G |
GNG3 |
G protein subunit gamma 3 |
multiple interactions affects localization |
ISO |
[Isoproterenol co-treated with Atorvastatin] affects the localization of GNG3 protein Atorvastatin affects the localization of GNG3 protein |
CTD |
PMID:19136528 |
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NCBI chr11:62,706,446...62,709,201
Ensembl chr11:62,707,676...62,709,201
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G |
GOT1 |
glutamic-oxaloacetic transaminase 1 |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [Streptozocin results in increased secretion of GOT1 protein] |
CTD |
PMID:30657622 |
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NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624
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G |
GPAM |
glycerol-3-phosphate acyltransferase, mitochondrial |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [Fructose results in increased expression of GPAM mRNA] |
CTD |
PMID:19053045 |
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NCBI chr10:112,149,865...112,227,677
Ensembl chr10:112,149,865...112,215,377
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G |
GPT |
glutamic--pyruvic transaminase |
multiple interactions |
ISO |
[Atorvastatin co-treated with Ciprofloxacin] results in increased expression of GPT protein; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the activity of GPT protein]; Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of GPT protein]; Buthionine Sulfoximine promotes the reaction [[Atorvastatin co-treated with Ciprofloxacin] results in increased expression of GPT protein] [Atorvastatin co-treated with triptolide] results in increased expression of GPT protein; [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of GPT protein]; Atorvastatin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of GPT protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased secretion of GPT protein] |
CTD |
PMID:29679711 PMID:30657622 PMID:32259528 PMID:32976958 PMID:33600922 PMID:37023836 More...
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NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
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G |
GPX4 |
glutathione peroxidase 4 |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of GPX4 protein] |
CTD |
PMID:32976958 |
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NCBI chr19:1,103,994...1,106,779
Ensembl chr19:1,103,982...1,106,791
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G |
HBEGF |
heparin binding EGF like growth factor |
decreases expression |
ISO |
Atorvastatin results in decreased expression of HBEGF protein |
CTD |
PMID:18360054 |
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NCBI chr 5:140,332,843...140,346,603
Ensembl chr 5:140,332,843...140,346,603
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G |
HMGCR |
3-hydroxy-3-methylglutaryl-CoA reductase |
multiple interactions affects binding increases expression increases activity |
EXP ISO |
Atorvastatin results in increased expression of and results in increased activity of HMGCR protein Atorvastatin binds to HMGCR protein Atorvastatin inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in decreased expression of HMGCR mRNA]; Atorvastatin inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in increased activity of HMGCR protein]; Atorvastatin inhibits the reaction [Dietary Fats results in increased expression of HMGCR mRNA]; Atorvastatin results in increased expression of and results in increased activity of HMGCR protein; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased activity of HMGCR protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased expression of HMGCR mRNA] |
CTD |
PMID:9512650 PMID:10357840 PMID:12056585 PMID:12065722 PMID:12612140 PMID:30273964 PMID:32048413 More...
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NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
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G |
HMOX1 |
heme oxygenase 1 |
increases expression multiple interactions |
EXP ISO |
Atorvastatin results in increased expression of HMOX1 mRNA Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of HMOX1 protein] [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; Atorvastatin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of HMOX1 protein] |
CTD |
PMID:16410222 PMID:32259528 PMID:32976958 |
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NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
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G |
HNF4A |
hepatocyte nuclear factor 4 alpha |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in decreased expression of HNF4A mRNA] |
CTD |
PMID:30273964 |
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NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,699...44,432,845
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G |
ICAM1 |
intercellular adhesion molecule 1 |
multiple interactions increases expression |
EXP ISO |
Atorvastatin inhibits the reaction [TNF results in increased expression of ICAM1] Atorvastatin results in increased expression of ICAM1 protein Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of ICAM1 protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein] |
CTD |
PMID:12615677 PMID:17589825 PMID:19171469 PMID:25058445 |
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NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
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G |
IKBKB |
inhibitor of nuclear factor kappa B kinase subunit beta |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [Sodium Glutamate results in increased phosphorylation of IKBKB protein] |
CTD |
PMID:19800637 |
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NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460
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G |
IL12A |
interleukin 12A |
decreases expression |
EXP |
Atorvastatin results in decreased expression of IL12A mRNA |
CTD |
PMID:12492458 |
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NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019
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G |
IL18 |
interleukin 18 |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL18 protein] |
CTD |
PMID:37023836 |
|
NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
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G |
IL1B |
interleukin 1 beta |
multiple interactions |
EXP ISO |
Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of IL1B mRNA]; Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of IL1B protein]; Atorvastatin inhibits the reaction [Particulate Matter results in increased expression of IL1B mRNA]; Atorvastatin inhibits the reaction [Particulate Matter results in increased expression of IL1B protein] Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL1B mRNA]; Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL1B protein] [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of IL1B protein]; Atorvastatin inhibits the reaction [[Dietary Fats co-treated with Ergocalciferols] results in increased expression of IL1B protein]; Atorvastatin inhibits the reaction [Dietary Fats results in increased expression of IL1B protein]; Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of IL1B protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of IL1B protein] |
CTD |
PMID:17589825 PMID:19482827 PMID:25058445 PMID:32048413 PMID:34939712 PMID:37023836 PMID:38213245 More...
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NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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G |
IL2RA |
interleukin 2 receptor subunit alpha |
affects expression |
EXP |
Atorvastatin affects the expression of IL2RA protein |
CTD |
PMID:16387846 |
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NCBI chr10:6,010,689...6,062,367
Ensembl chr10:6,010,689...6,062,370
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G |
IL6 |
interleukin 6 |
multiple interactions decreases expression decreases secretion |
EXP ISO |
Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of IL6 mRNA]; Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of IL6 protein]; Atorvastatin inhibits the reaction [Particulate Matter results in increased expression of IL6 mRNA]; Atorvastatin inhibits the reaction [Particulate Matter results in increased expression of IL6 protein]; Atorvastatin inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Atorvastatin promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Atorvastatin results in decreased expression of and results in decreased secretion of IL6 protein; Mevalonic Acid inhibits the reaction [Atorvastatin inhibits the reaction [TNF results in increased expression of IL6 mRNA]]; Mevalonic Acid inhibits the reaction [Atorvastatin results in decreased expression of IL6 mRNA] Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 protein]; Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of IL6 mRNA]; Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of IL6 protein] Atorvastatin results in decreased expression of IL6 mRNA; Atorvastatin results in decreased expression of IL6 protein Atorvastatin inhibits the reaction [[Dietary Fats co-treated with Ergocalciferols] results in increased expression of IL6 protein]; Atorvastatin inhibits the reaction [Dietary Fats results in increased expression of IL6 protein]; Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of IL6 protein] Atorvastatin results in decreased secretion of IL6 protein |
CTD |
PMID:12117737 PMID:16387846 PMID:17521631 PMID:19171469 PMID:19482827 PMID:19800637 PMID:25058445 PMID:25834641 PMID:32048413 PMID:37023836 PMID:38213245 More...
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NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
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G |
INS |
insulin |
increases expression |
EXP |
Atorvastatin results in increased expression of INS protein |
CTD |
PMID:19651449 |
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NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
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G |
INS-IGF2 |
INS-IGF2 readthrough |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of INS1 protein] [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of INS1 protein] |
CTD |
PMID:19800637 PMID:34939712 |
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NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209
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G |
IRAK1 |
interleukin 1 receptor associated kinase 1 |
multiple interactions |
EXP |
[Atorvastatin co-treated with Enalapril] results in decreased expression of IRAK1 mRNA; [Atorvastatin co-treated with Telmisartan] results in decreased expression of IRAK1 mRNA |
CTD |
PMID:20524934 |
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NCBI chr X:154,010,507...154,019,902
Ensembl chr X:154,010,506...154,019,902
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G |
IRF4 |
interferon regulatory factor 4 |
decreases expression |
ISO |
Atorvastatin results in decreased expression of IRF4 protein |
CTD |
PMID:33034787 |
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NCBI chr 6:391,752...411,443
Ensembl chr 6:391,739...411,443
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G |
ITGA2 |
integrin subunit alpha 2 |
multiple interactions |
EXP ISO |
Atorvastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]; geranylgeraniol inhibits the reaction [Atorvastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]] |
CTD |
PMID:12500026 |
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NCBI chr 5:52,989,352...53,094,779
Ensembl chr 5:52,989,340...53,094,779
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G |
ITGAL |
integrin subunit alpha L |
multiple interactions |
EXP |
Atorvastatin inhibits the reaction [TNF results in increased expression of ITGAL] |
CTD |
PMID:12615677 |
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NCBI chr16:30,472,742...30,523,185
Ensembl chr16:30,472,658...30,523,567
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G |
ITGAM |
integrin subunit alpha M |
decreases expression |
EXP |
Atorvastatin results in decreased expression of ITGAM protein |
CTD |
PMID:18333374 |
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NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892
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G |
ITGAX |
integrin subunit alpha X |
decreases expression |
EXP |
Atorvastatin results in decreased expression of ITGAX protein |
CTD |
PMID:18333374 |
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NCBI chr16:31,355,176...31,382,999
Ensembl chr16:31,355,134...31,382,999
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G |
ITGB1 |
integrin subunit beta 1 |
multiple interactions increases expression |
EXP ISO |
Atorvastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]; geranylgeraniol inhibits the reaction [Atorvastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased expression of ITGB1 mRNA] |
CTD |
PMID:12500026 |
|
NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792
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G |
ITGB2 |
integrin subunit beta 2 |
multiple interactions |
EXP |
Atorvastatin inhibits the reaction [TNF results in increased expression of ITGB2] |
CTD |
PMID:12615677 |
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NCBI chr21:44,885,953...44,928,815
Ensembl chr21:44,885,953...44,931,989
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G |
JUN |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
EXP |
[Atorvastatin co-treated with Celecoxib] results in increased expression of JUN protein; Atorvastatin results in increased phosphorylation of and results in increased activity of JUN protein; Celecoxib promotes the reaction [Atorvastatin results in increased phosphorylation of and results in increased activity of JUN protein] |
CTD |
PMID:18172863 |
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NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
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G |
KCNH2 |
potassium voltage-gated channel subfamily H member 2 |
decreases activity multiple interactions |
ISO |
Atorvastatin results in decreased activity of KCNH2 protein Berberine promotes the reaction [Atorvastatin results in decreased activity of KCNH2 protein] |
CTD |
PMID:30086269 |
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NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321
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G |
KHK |
ketohexokinase |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [Fructose results in increased expression of KHK protein] |
CTD |
PMID:21122807 |
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NCBI chr 2:27,086,772...27,100,762
Ensembl chr 2:27,086,772...27,100,762
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G |
KIF6 |
kinesin family member 6 |
increases response to substance |
EXP |
KIF6 polymorphism results in increased susceptibility to Atorvastatin |
CTD |
PMID:21943003 |
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NCBI chr 6:39,329,990...39,725,408
Ensembl chr 6:39,329,990...39,725,408
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G |
KPNA2 |
karyopherin subunit alpha 2 |
multiple interactions affects localization |
EXP |
[Ivermectin co-treated with Atorvastatin] affects the localization of KPNA2 protein Atorvastatin affects the localization of KPNA2 protein |
CTD |
PMID:34696514 |
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NCBI chr17:68,035,735...68,046,854
Ensembl chr17:68,035,636...68,047,364
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G |
KPNA7 |
karyopherin subunit alpha 7 |
multiple interactions |
EXP |
Atorvastatin inhibits the reaction [Poly I-C results in increased expression of KPNA7 mRNA] |
CTD |
PMID:34696514 |
|
NCBI chr 7:99,145,804...99,219,419
Ensembl chr 7:99,173,572...99,250,075
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G |
LCAT |
lecithin-cholesterol acyltransferase |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in increased activity of LCAT protein] |
CTD |
PMID:30273964 |
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NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131
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G |
LCN2 |
lipocalin 2 |
multiple interactions |
ISO |
[Buthionine Sulfoximine co-treated with Atorvastatin co-treated with Ciprofloxacin] results in increased expression of LCN2 mRNA [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of LCN2 protein]; Atorvastatin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of LCN2 protein] |
CTD |
PMID:29679711 PMID:32259528 |
|
NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453
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G |
LDLR |
low density lipoprotein receptor |
increases activity multiple interactions increases expression |
EXP ISO |
Atorvastatin results in increased activity of LDLR protein Atorvastatin inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in decreased expression of LDLR mRNA]; Atorvastatin inhibits the reaction [Dietary Fats results in decreased expression of LDLR mRNA] Atorvastatin results in increased expression of LDLR mRNA |
CTD |
PMID:10357840 PMID:11728391 PMID:12612140 PMID:24502637 PMID:30273964 PMID:32048413 More...
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NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820
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G |
LEP |
leptin |
multiple interactions |
ISO |
Atorvastatin affects the reaction [Fructose results in increased expression of LEP protein] |
CTD |
PMID:21122807 |
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NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629
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G |
LPL |
lipoprotein lipase |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in increased activity of LPL protein] |
CTD |
PMID:30273964 |
|
NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259
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G |
MAP1LC3B |
microtubule associated protein 1 light chain 3 beta |
multiple interactions |
ISO |
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased lipidation of MAP1LC3B protein] |
CTD |
PMID:34939712 |
|
NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
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G |
MAPK1 |
mitogen-activated protein kinase 1 |
multiple interactions increases phosphorylation decreases phosphorylation |
EXP ISO |
geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin results in decreased phosphorylation of MAPK1 protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in decreased phosphorylation of MAPK1 protein]; RHOA mutant form inhibits the reaction [Atorvastatin results in decreased phosphorylation of MAPK1 protein] Atorvastatin inhibits the reaction [AGT protein results in increased activity of MAPK1 protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Atorvastatin results in increased phosphorylation of MAPK1 protein] Atorvastatin inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
CTD |
PMID:16470222 PMID:18339080 PMID:18360054 PMID:19451411 |
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NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
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G |
MAPK14 |
mitogen-activated protein kinase 14 |
multiple interactions |
ISO EXP |
Atorvastatin inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein] Atorvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK14 protein] |
CTD |
PMID:17589825 PMID:19767766 PMID:20018284 PMID:20305681 |
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NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,782...36,111,236
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G |
MAPK3 |
mitogen-activated protein kinase 3 |
multiple interactions decreases phosphorylation increases phosphorylation |
EXP ISO |
geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin results in decreased phosphorylation of MAPK3 protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in decreased phosphorylation of MAPK3 protein]; RHOA mutant form inhibits the reaction [Atorvastatin results in decreased phosphorylation of MAPK3 protein] Atorvastatin inhibits the reaction [AGT protein results in increased activity of MAPK3 protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Atorvastatin results in increased phosphorylation of MAPK3 protein] Atorvastatin inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
CTD |
PMID:16470222 PMID:18339080 PMID:18360054 PMID:19451411 |
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NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
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G |
MB |
myoglobin |
increases expression multiple interactions |
ISO |
Atorvastatin results in increased expression of MB protein [Buthionine Sulfoximine co-treated with Atorvastatin co-treated with Ciprofloxacin] results in increased secretion of MB protein |
CTD |
PMID:27815113 PMID:29679711 |
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NCBI chr22:35,606,764...35,623,354
Ensembl chr22:35,606,764...35,637,951
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G |
MCL1 |
MCL1 apoptosis regulator, BCL2 family member |
decreases expression |
EXP |
Atorvastatin results in decreased expression of MCL1 protein |
CTD |
PMID:16470222 |
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NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,560,895...150,579,738
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G |
MDM2 |
MDM2 proto-oncogene |
increases expression |
EXP |
Atorvastatin results in increased expression of MDM2 protein |
CTD |
PMID:29630879 |
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NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544
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G |
MEF2D |
myocyte enhancer factor 2D |
increases expression |
ISO |
Atorvastatin results in increased expression of MEF2D mRNA |
CTD |
PMID:27377005 |
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NCBI chr 1:156,463,727...156,500,775
Ensembl chr 1:156,463,727...156,500,779
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G |
MFN2 |
mitofusin 2 |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of MFN2 protein] |
CTD |
PMID:24721408 |
|
NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211
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G |
MIR133B |
microRNA 133b |
multiple interactions |
ISO |
[Buthionine Sulfoximine co-treated with Atorvastatin co-treated with Ciprofloxacin] results in increased expression of MIR133B mRNA |
CTD |
PMID:29679711 |
|
NCBI chr 6:52,148,923...52,149,041
Ensembl chr 6:52,148,923...52,149,041
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G |
MIR145 |
microRNA 145 |
increases expression |
EXP |
Atorvastatin results in increased expression of MIR145 mRNA |
CTD |
PMID:29630879 |
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NCBI chr 5:149,430,646...149,430,733
Ensembl chr 5:149,430,646...149,430,733
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G |
MIR146A |
microRNA 146a |
multiple interactions |
EXP |
[Atorvastatin co-treated with Enalapril] results in decreased expression of MIR146A; [Atorvastatin co-treated with Telmisartan] results in decreased expression of MIR146A |
CTD |
PMID:20524934 |
|
NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450
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G |
MIR146B |
microRNA 146b |
multiple interactions |
EXP |
[Atorvastatin co-treated with Enalapril] results in decreased expression of MIR146B; [Atorvastatin co-treated with Telmisartan] results in decreased expression of MIR146B |
CTD |
PMID:20524934 |
|
NCBI chr10:102,436,512...102,436,584
Ensembl chr10:102,436,512...102,436,584
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G |
MIR206 |
microRNA 206 |
multiple interactions |
ISO |
[Buthionine Sulfoximine co-treated with Atorvastatin co-treated with Ciprofloxacin] results in increased expression of MIR206 mRNA |
CTD |
PMID:29679711 |
|
NCBI chr 6:52,144,349...52,144,434
Ensembl chr 6:52,144,349...52,144,434
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G |
MIR221 |
microRNA 221 |
decreases expression |
EXP |
Atorvastatin results in decreased expression of MIR221 |
CTD |
PMID:25517390 |
|
NCBI chr X:45,746,157...45,746,266
Ensembl chr X:45,746,157...45,746,266
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G |
MIR222 |
microRNA 222 |
decreases expression |
EXP |
Atorvastatin results in decreased expression of MIR222 |
CTD |
PMID:25517390 |
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NCBI chr X:45,747,015...45,747,124
Ensembl chr X:45,747,015...45,747,124
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G |
MLXIPL |
MLX interacting protein like |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [Fructose affects the localization of and results in increased activity of MLXIPL protein]; Atorvastatin inhibits the reaction [Fructose results in increased expression of MLXIPL protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Atorvastatin inhibits the reaction [Fructose results in increased activity of MLXIPL protein]] |
CTD |
PMID:19053045 PMID:21122807 |
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NCBI chr 7:73,593,202...73,647,907
Ensembl chr 7:73,593,194...73,624,543
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G |
MMP2 |
matrix metallopeptidase 2 |
decreases expression increases activity |
ISO |
Atorvastatin results in decreased expression of MMP2 protein Atorvastatin results in increased activity of MMP2 protein |
CTD |
PMID:18360054 PMID:23831763 |
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NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
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G |
MMP9 |
matrix metallopeptidase 9 |
multiple interactions increases activity |
EXP ISO |
Atorvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Atorvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Sildenafil Citrate promotes the reaction [Atorvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]] Atorvastatin results in increased activity of MMP9 protein |
CTD |
PMID:15728660 PMID:23831763 PMID:26614570 |
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NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
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G |
MPO |
myeloperoxidase |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [Paraquat results in increased activity of MPO protein] |
CTD |
PMID:27883937 |
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NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
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G |
MSR1 |
macrophage scavenger receptor 1 |
multiple interactions |
EXP |
[Rosiglitazone co-treated with Atorvastatin] results in increased expression of MSR1 mRNA |
CTD |
PMID:15183127 |
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NCBI chr 8:16,107,881...16,192,651
Ensembl chr 8:16,107,878...16,567,490
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G |
MSTN |
myostatin |
increases expression |
ISO |
Atorvastatin results in increased expression of MSTN protein |
CTD |
PMID:33034787 |
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NCBI chr 2:190,055,700...190,062,729
Ensembl chr 2:190,055,700...190,062,729
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G |
MT-CO1 |
mitochondrially encoded cytochrome c oxidase I |
affects expression multiple interactions |
ISO |
Atorvastatin affects the expression of COX1 mRNA Quercetin inhibits the reaction [Atorvastatin affects the expression of COX1 mRNA] |
CTD |
PMID:21775390 |
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NCBI chr MT:5,904...7,445
Ensembl chr MT:5,904...7,445
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G |
MT2A |
metallothionein 2A |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [Fructose results in increased expression of MT2A mRNA] |
CTD |
PMID:21122807 |
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NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
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G |
MTOR |
mechanistic target of rapamycin kinase |
multiple interactions |
ISO |
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of and results in increased phosphorylation of MTOR protein] |
CTD |
PMID:34939712 |
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NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556
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G |
MTTP |
microsomal triglyceride transfer protein |
increases expression multiple interactions decreases expression |
ISO EXP |
Atorvastatin results in increased expression of MTTP mRNA Mevalonic Acid inhibits the reaction [Atorvastatin results in increased expression of MTTP mRNA] Atorvastatin results in decreased expression of MTTP mRNA |
CTD |
PMID:10357840 PMID:12056585 |
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NCBI chr 4:99,564,130...99,623,997
Ensembl chr 4:99,564,081...99,623,997
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G |
MYC |
MYC proto-oncogene, bHLH transcription factor |
decreases expression |
EXP |
Atorvastatin results in decreased expression of MYC mRNA |
CTD |
PMID:29630879 |
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NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
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G |
MYD88 |
MYD88 innate immune signal transduction adaptor |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [[Dietary Fats co-treated with Ergocalciferols] results in increased expression of MYD88 mRNA]; Atorvastatin inhibits the reaction [[Dietary Fats co-treated with Ergocalciferols] results in increased expression of MYD88 protein] |
CTD |
PMID:38213245 |
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NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024
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G |
MYH2 |
myosin heavy chain 2 |
multiple interactions affects expression |
ISO |
[PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of MYH2 protein Atorvastatin affects the expression of MYH2 protein |
CTD |
PMID:30511338 |
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NCBI chr17:10,521,148...10,549,658
Ensembl chr17:10,521,148...10,549,700
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G |
NFE2L1 |
NFE2 like bZIP transcription factor 1 |
increases expression |
ISO |
Atorvastatin results in increased expression of NFE2L1 mRNA |
CTD |
PMID:30511338 |
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NCBI chr17:48,048,359...48,061,545
Ensembl chr17:48,048,329...48,061,545
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G |
NFE2L2 |
NFE2 like bZIP transcription factor 2 |
increases expression multiple interactions decreases expression |
ISO EXP |
Atorvastatin results in increased expression of NFE2L2 mRNA 2-tert-butylhydroquinone inhibits the reaction [Atorvastatin results in decreased expression of NFE2L2 protein] [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of NFE2L2 protein]; Atorvastatin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of NFE2L2 protein] [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of NFE2L2 mRNA; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of NFE2L2 protein] |
CTD |
PMID:30511338 PMID:31423616 PMID:32259528 PMID:32976958 |
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NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
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G |
NFKB1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
EXP ISO |
[Ivermectin co-treated with Atorvastatin] inhibits the reaction [Poly I-C results in increased expression of NFKB1 mRNA]; Atorvastatin inhibits the reaction [Poly I-C results in increased expression of NFKB1 mRNA] Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of NFKB1 mRNA] |
CTD |
PMID:34696514 PMID:37023836 |
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NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
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G |
NLRP3 |
NLR family pyrin domain containing 3 |
multiple interactions |
ISO |
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of NLRP3 protein] Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of NLRP3 mRNA] |
CTD |
PMID:34939712 PMID:37023836 |
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NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108
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G |
NNMT |
nicotinamide N-methyltransferase |
increases expression |
EXP |
Atorvastatin results in increased expression of NNMT protein |
CTD |
PMID:33073877 |
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NCBI chr11:114,257,806...114,313,536
Ensembl chr11:114,257,787...114,313,536
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G |
NOS2 |
nitric oxide synthase 2 |
multiple interactions decreases expression |
ISO |
Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of NOS2 mRNA]; Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of NOS2 protein] Atorvastatin results in decreased expression of NOS2 mRNA; Atorvastatin results in decreased expression of NOS2 protein |
CTD |
PMID:15166393 PMID:25058445 PMID:25218292 |
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NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
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G |
NOS3 |
nitric oxide synthase 3 |
multiple interactions increases expression affects response to substance |
EXP ISO |
Atorvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of NOS3 mRNA]; Atorvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of NOS3 protein]; Melatonin promotes the reaction [Atorvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of NOS3 protein]] Atorvastatin results in increased expression of NOS3 mRNA; Atorvastatin results in increased expression of NOS3 protein [Dexamethasone co-treated with Atorvastatin] results in increased expression of NOS3 mRNA; [Losartan co-treated with Atorvastatin] results in increased expression of NOS3 mRNA; Atorvastatin inhibits the reaction [Dexamethasone results in decreased expression of NOS3 mRNA]; Atorvastatin inhibits the reaction [sodium arsenite results in decreased expression of and results in decreased phosphorylation of NOS3 protein]; Atorvastatin inhibits the reaction [sodium arsenite results in decreased expression of NOS3 mRNA]; Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of NOS3 protein]; Atorvastatin inhibits the reaction [Streptozocin results in decreased expression of NOS3 protein] Atorvastatin inhibits the reaction [Homocysteine results in decreased expression of NOS3 mRNA]; Atorvastatin inhibits the reaction [Homocysteine results in decreased phosphorylation of NOS3 protein] NOS3 promoter SNP affects the susceptibility to Atorvastatin |
CTD |
PMID:12490971 PMID:15166393 PMID:16410222 PMID:16962929 PMID:17042910 PMID:17589825 PMID:20305681 PMID:21585521 PMID:23091284 PMID:25058445 PMID:25218292 PMID:25517390 More...
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NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
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G |
NOX1 |
NADPH oxidase 1 |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [AGT protein results in increased expression of NOX1 protein] |
CTD |
PMID:19451411 |
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NCBI chr X:100,843,324...100,874,359
Ensembl chr X:100,843,324...100,874,359
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G |
NOX4 |
NADPH oxidase 4 |
multiple interactions |
ISO EXP |
Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of NOX4 mRNA] Atorvastatin inhibits the reaction [Homocysteine results in increased expression of NOX4 mRNA] |
CTD |
PMID:20018284 PMID:25218292 |
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NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187
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G |
NPPA |
natriuretic peptide A |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA] |
CTD |
PMID:19136528 |
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NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345
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G |
NPPB |
natriuretic peptide B |
decreases expression |
ISO |
Atorvastatin results in decreased expression of NPPB protein |
CTD |
PMID:18360054 |
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NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945
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G |
NR0B2 |
nuclear receptor subfamily 0 group B member 2 |
decreases expression |
ISO |
Atorvastatin results in decreased expression of NR0B2 mRNA |
CTD |
PMID:25278499 |
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NCBI chr 1:26,911,489...26,913,975
Ensembl chr 1:26,911,489...26,913,975
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G |
NR1I2 |
nuclear receptor subfamily 1 group I member 2 |
multiple interactions increases expression |
EXP ISO |
[Atorvastatin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA; [Atorvastatin co-treated with NR1I2 protein] results in increased expression of SGK2 mRNA; NR1I2 protein promotes the reaction [Atorvastatin results in decreased expression of GCK protein]; NR1I2 protein promotes the reaction [Atorvastatin results in decreased expression of SLC2A2 protein] Atorvastatin promotes the reaction [Dietary Fats results in increased expression of NR1I2 protein] Atorvastatin binds to and results in increased activity of NR1I2 protein Atorvastatin results in increased expression of NR1I2 protein |
CTD |
PMID:15986414 PMID:24204015 PMID:26616219 |
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NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487
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G |
NR1I3 |
nuclear receptor subfamily 1 group I member 3 |
increases activity |
EXP ISO |
Atorvastatin results in increased activity of NR1I3 protein |
CTD |
PMID:15802384 |
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NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244
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G |
NRF1 |
nuclear respiratory factor 1 |
multiple interactions affects expression increases expression |
ISO |
Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of NRF1 mRNA]; Quercetin inhibits the reaction [Atorvastatin affects the expression of NRF1 mRNA] |
CTD |
PMID:21775390 |
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NCBI chr 7:129,611,720...129,757,076
Ensembl chr 7:129,611,720...129,757,082
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G |
PARP1 |
poly(ADP-ribose) polymerase 1 |
multiple interactions increases cleavage |
EXP ISO |
2-tert-butylhydroquinone inhibits the reaction [Atorvastatin results in increased cleavage of PARP1 protein]; [Atorvastatin co-treated with Celecoxib] results in increased cleavage of PARP1 protein; bafilomycin A1 promotes the reaction [Atorvastatin results in increased cleavage of PARP1 protein]; CDKN1A protein mutant form inhibits the reaction [Atorvastatin results in increased cleavage of PARP1 protein] ATG5 mutant form promotes the reaction [Atorvastatin results in increased cleavage of PARP1 protein] |
CTD |
PMID:16470222 PMID:18172863 PMID:20876807 PMID:31423616 |
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NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
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G |
PCYT1A |
phosphate cytidylyltransferase 1A, choline |
increases activity |
ISO |
Atorvastatin results in increased activity of PCYT1A protein |
CTD |
PMID:12056585 |
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NCBI chr 3:196,234,368...196,287,726
Ensembl chr 3:196,214,222...196,287,957
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G |
PDK4 |
pyruvate dehydrogenase kinase 4 |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [TNF protein results in decreased expression of PDK4 protein]; Mevalonic Acid inhibits the reaction [Atorvastatin inhibits the reaction [TNF protein results in decreased expression of PDK4 protein]] |
CTD |
PMID:22343369 |
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NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516
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G |
PDPK1 |
3-phosphoinositide dependent protein kinase 1 |
multiple interactions |
EXP |
[Atorvastatin co-treated with Celecoxib] results in decreased phosphorylation of and results in decreased expression of PDPK1 protein |
CTD |
PMID:18172863 |
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NCBI chr16:2,538,021...2,603,188
Ensembl chr16:2,537,979...2,603,188
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G |
PIK3CA |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
decreases expression |
EXP |
Atorvastatin results in decreased expression of PIK3CA mRNA |
CTD |
PMID:29630879 |
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NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093
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G |
PKLR |
pyruvate kinase L/R |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [Fructose results in increased expression of PKLR mRNA] |
CTD |
PMID:19053045 PMID:21122807 |
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NCBI chr 1:155,289,293...155,308,654
Ensembl chr 1:155,289,293...155,301,438
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G |
PKM |
pyruvate kinase M1/2 |
increases expression |
ISO |
Atorvastatin results in increased expression of PKM mRNA |
CTD |
PMID:27377005 |
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NCBI chr15:72,199,029...72,231,591
Ensembl chr15:72,199,029...72,231,819
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G |
PLAU |
plasminogen activator, urokinase |
decreases expression |
EXP |
Atorvastatin results in decreased expression of PLAU protein |
CTD |
PMID:16410222 |
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NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496
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G |
PLIN2 |
perilipin 2 |
multiple interactions |
ISO |
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of PLIN2 protein] |
CTD |
PMID:34939712 |
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NCBI chr 9:19,108,388...19,127,492
Ensembl chr 9:19,108,375...19,149,290
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G |
POMC |
proopiomelanocortin |
increases expression |
ISO |
Atorvastatin results in increased expression of POMC protein |
CTD |
PMID:29574565 |
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NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903
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G |
PON1 |
paraoxonase 1 |
increases activity multiple interactions increases expression |
EXP ISO |
Atorvastatin results in increased activity of PON1 protein Atorvastatin inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in decreased secretion of PON1 protein] PON1 gene polymorphism affects the reaction [Atorvastatin results in increased abundance of Cholesterol, HDL]; PON1 gene SNP affects the reaction [Atorvastatin results in increased abundance of Cholesterol, HDL]; PON1 protein affects the reaction [Atorvastatin results in increased abundance of Cholesterol, HDL] Atorvastatin results in increased expression of PON1 mRNA |
CTD |
PMID:15324535 PMID:15690306 PMID:15969877 PMID:16238680 PMID:30273964 |
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NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
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G |
PON2 |
paraoxonase 2 |
increases activity increases expression |
EXP |
Atorvastatin results in increased activity of PON2 protein Atorvastatin results in increased expression of PON2 mRNA |
CTD |
PMID:14592851 |
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NCBI chr 7:95,404,862...95,435,028
Ensembl chr 7:95,404,862...95,435,329
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G |
PPARA |
peroxisome proliferator activated receptor alpha |
decreases expression multiple interactions |
EXP ISO |
Atorvastatin results in decreased expression of PPARA mRNA Atorvastatin promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]] [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of PPARA protein]; Atorvastatin inhibits the reaction [Fructose results in increased expression of PPARA protein] |
CTD |
PMID:12065722 PMID:18812576 PMID:21554872 PMID:32259528 |
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NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
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G |
PPARGC1A |
PPARG coactivator 1 alpha |
decreases expression affects expression multiple interactions increases expression |
ISO |
Atorvastatin results in decreased expression of PPARGC1A mRNA Atorvastatin results in decreased expression of PPARGC1A protein Atorvastatin affects the expression of PPARGC1A mRNA [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of PPARGC1A mRNA Atorvastatin results in increased expression of PPARGC1A mRNA [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of PPARGC1A protein]; Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of PPARGC1A mRNA]; Atorvastatin inhibits the reaction [TNF protein results in decreased expression of PPARGC1A protein]; Farnesol inhibits the reaction [Atorvastatin inhibits the reaction [TNF protein results in decreased expression of PPARGC1A protein]] |
CTD |
PMID:21775390 PMID:22343369 PMID:30511338 PMID:32259528 |
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NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
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G |
PPARGC1B |
PPARG coactivator 1 beta |
affects expression decreases expression affects response to substance multiple interactions |
ISO |
Atorvastatin affects the expression of PPARGC1B mRNA Atorvastatin affects the expression of PPARGC1B protein Atorvastatin results in decreased expression of PPARGC1B mRNA PPARGC1B protein affects the susceptibility to Atorvastatin [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the cleavage of CASP3 protein; [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of MYH2 protein; [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of NFE2L2 mRNA; [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of PPARGC1A mRNA; [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of PPARGC1B mRNA; [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of SOD2 protein; [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of TFAM mRNA; [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of TOMM20 protein Quercetin inhibits the reaction [Atorvastatin affects the expression of PPARGC1B mRNA] |
CTD |
PMID:21775390 PMID:30511338 |
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NCBI chr 5:149,730,310...149,857,959
Ensembl chr 5:149,730,298...149,855,022
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G |
PPP3CA |
protein phosphatase 3 catalytic subunit alpha |
increases expression |
ISO |
Atorvastatin results in increased expression of PPP3CA mRNA |
CTD |
PMID:27377005 |
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NCBI chr 4:101,023,418...101,347,526
Ensembl chr 4:101,023,409...101,348,278
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G |
PRKAA1 |
protein kinase AMP-activated catalytic subunit alpha 1 |
increases activity |
EXP |
Atorvastatin results in increased activity of PRKAA1 protein |
CTD |
PMID:33073877 |
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NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374
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G |
PRKACA |
protein kinase cAMP-activated catalytic subunit alpha |
multiple interactions |
ISO |
Atorvastatin results in increased phosphorylation of and results in increased activity of PRKACA protein; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Atorvastatin results in increased phosphorylation of and results in increased activity of PRKACA protein] |
CTD |
PMID:19053045 |
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NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084
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G |
PRKCA |
protein kinase C alpha |
multiple interactions |
ISO |
[Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of and results in increased phosphorylation of PRKCA protein] |
CTD |
PMID:32259528 |
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NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743
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G |
PRKCQ |
protein kinase C theta |
increases expression |
ISO |
Atorvastatin results in increased expression of PRKCQ mRNA; Atorvastatin results in increased expression of PRKCQ protein |
CTD |
PMID:27377005 |
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NCBI chr10:6,394,097...6,580,646
Ensembl chr10:6,427,143...6,580,301
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G |
PRKCZ |
protein kinase C zeta |
multiple interactions |
ISO |
[Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of PRKCZ protein] |
CTD |
PMID:32259528 |
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NCBI chr 1:2,048,504...2,185,395
Ensembl chr 1:2,050,411...2,185,395
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G |
PTEN |
phosphatase and tensin homolog |
increases expression |
ISO |
Atorvastatin results in increased expression of PTEN protein |
CTD |
PMID:15837263 |
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NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
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G |
PTGS2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression |
ISO |
[Atorvastatin co-treated with Pioglitazone] results in increased expression of PTGS2 protein; [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of PTGS2 protein] Atorvastatin results in increased expression of PTGS2 protein |
CTD |
PMID:16908763 PMID:34939712 |
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NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
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G |
RAC1 |
Rac family small GTPase 1 |
multiple interactions |
EXP ISO |
[Poly I-C co-treated with Atorvastatin] results in decreased expression of RAC1 mRNA; Atorvastatin inhibits the reaction [Glucose results in increased localization of RAC1 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin inhibits the reaction [Glucose results in increased localization of RAC1 protein]] Atorvastatin inhibits the reaction [Streptozocin results in increased activity of RAC1 protein] Atorvastatin inhibits the reaction [Streptozocin results in increased activity of and results in increased localization of RAC1 protein] |
CTD |
PMID:17279352 PMID:17589825 PMID:34696514 |
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NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967
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G |
RB1 |
RB transcriptional corepressor 1 |
multiple interactions |
EXP |
[Atorvastatin co-treated with Celecoxib] results in decreased expression of RB1 protein modified form; [Atorvastatin co-treated with Celecoxib] results in increased expression of RB1 protein |
CTD |
PMID:18172863 |
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NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436
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G |
RELA |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of RELA protein]; Atorvastatin inhibits the reaction [[Dietary Fats co-treated with Ergocalciferols] results in increased expression of RELA mRNA]; Atorvastatin inhibits the reaction [[Dietary Fats co-treated with Ergocalciferols] results in increased expression of RELA protein]; Atorvastatin inhibits the reaction [Nitroglycerin results in increased localization of RELA protein] Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of RELA protein] |
CTD |
PMID:19733216 PMID:34939712 PMID:37121058 PMID:38213245 |
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NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
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G |
RHOA |
ras homolog family member A |
increases expression decreases activity multiple interactions decreases localization |
EXP ISO |
Atorvastatin results in increased expression of RHOA protein Atorvastatin results in decreased activity of RHOA protein Atorvastatin inhibits the reaction [Streptozocin results in increased activity of RHOA protein] [Poly I-C co-treated with Atorvastatin co-treated with Ivermectin] results in increased expression of RHOA mRNA; [Poly I-C co-treated with Atorvastatin] results in increased expression of RHOA mRNA; Atorvastatin results in increased localization of and results in decreased prenylation of RHOA protein; Celecoxib promotes the reaction [Atorvastatin results in decreased localization of RHOA protein]; Celecoxib promotes the reaction [Atorvastatin results in increased expression of RHOA protein]; geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin results in decreased activity of RHOA protein]; geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin results in increased localization of RHOA protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in decreased activity of RHOA protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased localization of RHOA protein]; RHOA mutant form inhibits the reaction [Atorvastatin results in decreased expression of BCL2 protein]; RHOA mutant form inhibits the reaction [Atorvastatin results in decreased phosphorylation of MAPK1 protein]; RHOA mutant form inhibits the reaction [Atorvastatin results in decreased phosphorylation of MAPK3 protein]; RHOA protein inhibits the reaction [Atorvastatin results in increased activity of CASP3 protein] |
CTD |
PMID:16470222 PMID:17589825 PMID:18172863 PMID:34696514 |
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NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998
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G |
RHOB |
ras homolog family member B |
increases localization increases expression multiple interactions |
EXP |
Atorvastatin results in increased localization of RHOB protein Atorvastatin results in increased expression of RHOB protein [Atorvastatin co-treated with Celecoxib] results in increased localization of RHOB protein; Celecoxib promotes the reaction [Atorvastatin results in increased expression of RHOB protein] |
CTD |
PMID:18172863 |
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NCBI chr 2:20,447,074...20,449,440
Ensembl chr 2:20,447,074...20,449,440
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G |
RHOC |
ras homolog family member C |
decreases localization multiple interactions increases expression |
EXP |
Atorvastatin results in decreased localization of RHOC protein Celecoxib promotes the reaction [Atorvastatin results in decreased localization of RHOC protein]; Celecoxib promotes the reaction [Atorvastatin results in increased expression of RHOC protein] |
CTD |
PMID:18172863 |
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NCBI chr 1:112,701,131...112,707,408
Ensembl chr 1:112,701,127...112,707,434
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G |
SCARB1 |
scavenger receptor class B member 1 |
multiple interactions |
EXP |
[Rosiglitazone co-treated with Atorvastatin] results in increased expression of SCARB1 protein |
CTD |
PMID:15183127 |
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NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668
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G |
SCD |
stearoyl-CoA desaturase |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [Fructose results in increased expression of SCD1 mRNA] |
CTD |
PMID:21122807 |
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NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826
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G |
SELE |
selectin E |
increases expression |
EXP |
Atorvastatin results in increased expression of SELE protein |
CTD |
PMID:19171469 |
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NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705
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G |
SERPINE1 |
serpin family E member 1 |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [Fructose results in increased expression of SERPINE1 mRNA] |
CTD |
PMID:21122807 |
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NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
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G |
SGK2 |
serum/glucocorticoid regulated kinase 2 |
multiple interactions |
EXP |
[Atorvastatin co-treated with NR1I2 protein] results in increased expression of SGK2 mRNA |
CTD |
PMID:24204015 |
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NCBI chr20:43,559,027...43,585,627
Ensembl chr20:43,558,968...43,588,237
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G |
SIRT1 |
sirtuin 1 |
multiple interactions increases phosphorylation |
ISO EXP |
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of SIRT1 protein] Atorvastatin results in increased phosphorylation of SIRT1 protein |
CTD |
PMID:33073877 PMID:34939712 |
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NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
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G |
SLC10A1 |
solute carrier family 10 member 1 |
increases expression |
ISO |
Atorvastatin results in increased expression of SLC10A1 mRNA |
CTD |
PMID:25278499 |
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NCBI chr14:69,775,416...69,797,241
Ensembl chr14:69,775,416...69,797,241
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G |
SLC10A2 |
solute carrier family 10 member 2 |
increases expression |
ISO |
Atorvastatin results in increased expression of SLC10A2 mRNA; Atorvastatin results in increased expression of SLC10A2 protein |
CTD |
PMID:15986414 |
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NCBI chr13:103,043,998...103,066,417
Ensembl chr13:103,043,998...103,066,417
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G |
SLC1A2 |
solute carrier family 1 member 2 |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [APP protein results in decreased expression of SLC1A2 protein] |
CTD |
PMID:20816828 |
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NCBI chr11:35,251,205...35,420,507
Ensembl chr11:35,251,205...35,420,063
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G |
SLC1A3 |
solute carrier family 1 member 3 |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [APP protein results in decreased expression of SLC1A3 protein] |
CTD |
PMID:20816828 |
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NCBI chr 5:36,606,606...36,688,334
Ensembl chr 5:36,596,588...36,688,334
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G |
SLC22A1 |
solute carrier family 22 member 1 |
multiple interactions increases expression |
EXP ISO |
Atorvastatin inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] Atorvastatin results in increased expression of SLC22A1 mRNA |
CTD |
PMID:21641380 PMID:25278499 |
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NCBI chr 6:160,121,815...160,158,718
Ensembl chr 6:160,121,815...160,158,718
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G |
SLC22A3 |
solute carrier family 22 member 3 |
multiple interactions |
EXP |
Atorvastatin inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] |
CTD |
PMID:21641380 |
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NCBI chr 6:160,348,378...160,452,577
Ensembl chr 6:160,348,378...160,452,577
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G |
SLC22A5 |
solute carrier family 22 member 5 |
multiple interactions |
EXP |
Atorvastatin inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine] |
CTD |
PMID:21641380 |
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NCBI chr 5:132,369,710...132,395,612
Ensembl chr 5:132,369,710...132,395,613
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G |
SLC29A1 |
solute carrier family 29 member 1 (Augustine blood group) |
increases expression |
ISO |
Atorvastatin results in increased expression of SLC29A1 mRNA |
CTD |
PMID:25278499 |
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NCBI chr 6:44,219,615...44,234,142
Ensembl chr 6:44,219,553...44,234,142
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G |
SLC2A2 |
solute carrier family 2 member 2 |
decreases expression multiple interactions |
ISO EXP |
Atorvastatin results in decreased expression of SLC2A2 protein NR1I2 protein promotes the reaction [Atorvastatin results in decreased expression of SLC2A2 protein] |
CTD |
PMID:26616219 |
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NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743
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G |
SLC2A4 |
solute carrier family 2 member 4 |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [Sodium Glutamate results in decreased expression of SLC2A4 mRNA]; Atorvastatin inhibits the reaction [Sodium Glutamate results in decreased expression of SLC2A4 protein]; Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of SLC2A4 mRNA]; Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of SLC2A4 protein] |
CTD |
PMID:19800637 PMID:25834641 |
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NCBI chr17:7,281,718...7,288,257
Ensembl chr17:7,281,718...7,288,257
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G |
SLC4A1 |
solute carrier family 4 member 1 (Diego blood group) |
multiple interactions |
ISO |
[Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite affects the localization of SLC4A1 protein] |
CTD |
PMID:20946910 |
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NCBI chr17:44,248,390...44,268,135
Ensembl chr17:44,248,390...44,268,141
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G |
SLC6A4 |
solute carrier family 6 member 4 |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [Monocrotaline results in increased expression of SLC6A4 protein] |
CTD |
PMID:17575010 |
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NCBI chr17:30,194,319...30,235,697
Ensembl chr17:30,194,319...30,236,002
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G |
SLCO1A2 |
solute carrier organic anion transporter family member 1A2 |
decreases expression |
ISO |
Atorvastatin results in decreased expression of SLCO1A4 protein |
CTD |
PMID:24909372 |
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NCBI chr12:21,264,600...21,419,634
Ensembl chr12:21,264,600...21,419,594
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G |
SLCO1B1 |
solute carrier organic anion transporter family member 1B1 |
decreases activity increases uptake increases import decreases transport multiple interactions |
EXP |
Atorvastatin results in decreased activity of SLCO1B1 protein SLCO1B1 protein results in increased uptake of Atorvastatin SLCO1B1 protein results in increased import of Atorvastatin SLCO1B1 gene SNP results in decreased transport of Atorvastatin Apigenin inhibits the reaction [SLCO1B1 protein results in increased import of Atorvastatin]; Atorvastatin inhibits the reaction [SLCO1B1 protein results in increased transport of estradiol-17 beta-glucuronide]; glimepiride inhibits the reaction [SLCO1B1 protein results in increased uptake of Atorvastatin]; Glyburide inhibits the reaction [SLCO1B1 protein results in increased uptake of Atorvastatin]; kaempferol inhibits the reaction [SLCO1B1 protein results in increased import of Atorvastatin]; Nateglinide inhibits the reaction [SLCO1B1 protein results in increased uptake of Atorvastatin]; Pioglitazone inhibits the reaction [SLCO1B1 protein results in increased uptake of Atorvastatin]; Quercetin inhibits the reaction [SLCO1B1 protein results in increased import of Atorvastatin]; repaglinide inhibits the reaction [SLCO1B1 protein results in increased uptake of Atorvastatin]; Rosiglitazone inhibits the reaction [SLCO1B1 protein results in increased uptake of Atorvastatin]; Sulfobromophthalein inhibits the reaction [SLCO1B1 protein results in increased uptake of Atorvastatin] |
CTD |
PMID:15616150 PMID:15970799 PMID:22394605 PMID:23121773 PMID:25106415 |
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NCBI chr12:21,131,194...21,239,796
Ensembl chr12:21,131,194...21,239,796
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G |
SLCO1B3 |
solute carrier organic anion transporter family member 1B3 |
increases expression increases uptake multiple interactions |
ISO EXP |
Atorvastatin results in increased expression of SLCO1B2 mRNA SLCO1B3 protein results in increased uptake of Atorvastatin glimepiride affects the reaction [SLCO1B3 protein results in increased uptake of Atorvastatin]; Glyburide inhibits the reaction [SLCO1B3 protein results in increased uptake of Atorvastatin]; Nateglinide inhibits the reaction [SLCO1B3 protein results in increased uptake of Atorvastatin]; repaglinide inhibits the reaction [SLCO1B3 protein results in increased uptake of Atorvastatin]; Rosiglitazone inhibits the reaction [SLCO1B3 protein results in increased uptake of Atorvastatin]; Sulfobromophthalein inhibits the reaction [SLCO1B3 protein results in increased uptake of Atorvastatin] |
CTD |
PMID:23121773 PMID:25106415 PMID:25278499 |
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NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911
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G |
SLCO2B1 |
solute carrier organic anion transporter family member 2B1 |
multiple interactions increases uptake |
EXP |
glimepiride inhibits the reaction [SLCO2B1 protein results in increased uptake of Atorvastatin]; Glyburide inhibits the reaction [SLCO2B1 protein results in increased uptake of Atorvastatin]; Nateglinide inhibits the reaction [SLCO2B1 protein results in increased uptake of Atorvastatin]; repaglinide inhibits the reaction [SLCO2B1 protein results in increased uptake of Atorvastatin]; Rosiglitazone inhibits the reaction [SLCO2B1 protein results in increased uptake of Atorvastatin]; Sulfobromophthalein inhibits the reaction [SLCO2B1 protein results in increased uptake of Atorvastatin] |
CTD |
PMID:23121773 PMID:25106415 |
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NCBI chr11:75,151,107...75,206,549
Ensembl chr11:75,100,563...75,206,549
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G |
SOD1 |
superoxide dismutase 1 |
multiple interactions |
ISO |
Atorvastatin inhibits the reaction [AGT protein results in decreased expression of SOD1 protein] |
CTD |
PMID:19451411 |
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NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
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G |
SOD2 |
superoxide dismutase 2 |
multiple interactions affects expression decreases expression increases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of SOD2 mRNA]; Quercetin affects the reaction [Atorvastatin affects the expression of SOD2 mRNA] Atorvastatin affects the expression of SOD2 protein 2-tert-butylhydroquinone inhibits the reaction [Atorvastatin affects the expression of SOD2 protein] [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of SOD2 protein Atorvastatin results in decreased expression of SOD2 protein |
CTD |
PMID:21775390 PMID:30511338 PMID:31423616 |
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NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
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G |
SOD3 |
superoxide dismutase 3 |
increases expression |
ISO |
Atorvastatin results in increased expression of SOD3 protein |
CTD |
PMID:19451411 |
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NCBI chr 4:24,795,573...24,800,842
Ensembl chr 4:24,789,912...24,800,842
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G |
SQSTM1 |
sequestosome 1 |
multiple interactions |
ISO |
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of SQSTM1 protein] |
CTD |
PMID:34939712 |
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NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
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G |
SREBF1 |
sterol regulatory element binding transcription factor 1 |
multiple interactions |
ISO |
[Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of SREBF1 protein]; Atorvastatin inhibits the reaction [Fructose results in increased activity of SREBF1 protein] |
CTD |
PMID:19053045 PMID:32259528 |
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NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002
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G |
SREBF2 |
sterol regulatory element binding transcription factor 2 |
multiple interactions increases expression increases localization |
ISO EXP |
Atorvastatin results in increased activity of and results in increased localization of SREBF2 protein; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased expression of SREBF2 mRNA] Atorvastatin results in increased localization of SREBF2 protein |
CTD |
PMID:11728391 PMID:12056585 PMID:12065722 |
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NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,105...41,907,306
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G |
STAR |
steroidogenic acute regulatory protein |
affects expression |
ISO |
Atorvastatin affects the expression of STAR mRNA |
CTD |
PMID:29574565 |
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NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
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G |
SYP |
synaptophysin |
increases expression |
ISO |
Atorvastatin results in increased expression of SYP protein |
CTD |
PMID:15255259 |
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NCBI chr X:49,187,815...49,200,193
Ensembl chr X:49,187,815...49,200,218
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G |
TFAM |
transcription factor A, mitochondrial |
increases expression decreases expression multiple interactions |
ISO |
Atorvastatin results in increased expression of TFAM mRNA Atorvastatin results in decreased expression of TFAM protein [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of TFAM mRNA Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of TFAM mRNA] |
CTD |
PMID:21775390 PMID:30511338 |
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NCBI chr10:58,385,410...58,399,220
Ensembl chr10:58,385,345...58,399,220
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G |
TFRC |
transferrin receptor |
affects expression multiple interactions |
EXP ISO |
Atorvastatin affects the expression of TFRC protein Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of TFRC protein] |
CTD |
PMID:16387846 PMID:32976958 |
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NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153
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G |
TGFB1 |
transforming growth factor beta 1 |
multiple interactions |
ISO |
2-chloro-5-nitrobenzanilide inhibits the reaction [Atorvastatin inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA]]; Atorvastatin inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA] |
CTD |
PMID:24161914 |
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NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
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G |
THBS1 |
thrombospondin 1 |
decreases expression |
EXP |
Atorvastatin results in decreased expression of THBS1 mRNA |
CTD |
PMID:16410222 |
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NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466
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G |
TLR2 |
toll like receptor 2 |
increases expression |
EXP |
Atorvastatin results in increased expression of TLR2 protein |
CTD |
PMID:16387846 |
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NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260
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G |
TLR4 |
toll like receptor 4 |
multiple interactions decreases expression increases expression |
EXP ISO |
[Atorvastatin co-treated with Enalapril] results in decreased expression of TLR4 mRNA; [Atorvastatin co-treated with Enalapril] results in decreased expression of TLR4 protein; [Atorvastatin co-treated with Telmisartan] results in decreased expression of TLR4 mRNA; [Atorvastatin co-treated with Telmisartan] results in decreased expression of TLR4 protein Atorvastatin results in decreased expression of TLR4 mRNA; Atorvastatin results in decreased expression of TLR4 protein Atorvastatin inhibits the reaction [[Dietary Fats co-treated with Ergocalciferols] results in increased expression of TLR4 mRNA]; Atorvastatin inhibits the reaction [[Dietary Fats co-treated with Ergocalciferols] results in increased expression of TLR4 protein]; Atorvastatin inhibits the reaction [Paraquat results in increased expression of TLR4 mRNA]; Atorvastatin inhibits the reaction [Paraquat results in increased expression of TLR4 protein] Atorvastatin results in increased expression of TLR4 protein |
CTD |
PMID:16387846 PMID:20524934 PMID:27883937 PMID:38213245 |
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NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
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G |
TNF |
tumor necrosis factor |
multiple interactions decreases expression decreases secretion |
EXP ISO |
Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of TNF mRNA]; Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of TNF protein]; Atorvastatin inhibits the reaction [Particulate Matter results in increased expression of TNF mRNA]; Atorvastatin inhibits the reaction [Particulate Matter results in increased expression of TNF protein]; Atorvastatin inhibits the reaction [TNF protein results in decreased expression of and results in decreased secretion of FASLG protein modified form]; Atorvastatin inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Atorvastatin inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]; Atorvastatin inhibits the reaction [TNF results in increased expression of ICAM1]; Atorvastatin inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Atorvastatin inhibits the reaction [TNF results in increased expression of ITGAL]; Atorvastatin inhibits the reaction [TNF results in increased expression of ITGB2]; Atorvastatin promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Mevalonic Acid inhibits the reaction [Atorvastatin inhibits the reaction [TNF results in increased expression of CCL2 mRNA]]; Mevalonic Acid inhibits the reaction [Atorvastatin inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]]; Mevalonic Acid inhibits the reaction [Atorvastatin inhibits the reaction [TNF results in increased expression of IL6 mRNA]] Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF mRNA]; Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF protein]; Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of TNF mRNA]; Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of TNF protein] [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of TNF protein]; Atorvastatin inhibits the reaction [[Dietary Fats co-treated with Ergocalciferols] results in increased expression of TNF protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Atorvastatin inhibits the reaction [TNF protein results in decreased expression of PDK4 protein]; Atorvastatin inhibits the reaction [TNF protein results in decreased expression of PPARGC1A protein]; Atorvastatin inhibits the reaction [TNF protein results in increased oxidation of Glucose]; Farnesol inhibits the reaction [Atorvastatin inhibits the reaction [TNF protein results in decreased expression of PPARGC1A protein]]; Mevalonic Acid inhibits the reaction [Atorvastatin inhibits the reaction [TNF protein results in decreased expression of PDK4 protein]] Atorvastatin results in decreased expression of TNF mRNA Atorvastatin results in decreased secretion of TNF protein Atorvastatin results in decreased expression of TNF protein |
CTD |
PMID:12117737 PMID:12615677 PMID:15063428 PMID:16387846 PMID:17521631 PMID:17589825 PMID:19171469 PMID:19482827 PMID:19800637 PMID:22343369 PMID:29630879 PMID:34939712 PMID:37023836 PMID:38213245 More...
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NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
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G |
TNFRSF1A |
TNF receptor superfamily member 1A |
decreases expression |
EXP |
Atorvastatin results in decreased expression of TNFRSF1A protein |
CTD |
PMID:16360360 |
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NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114
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G |
TNFSF10 |
TNF superfamily member 10 |
increases response to substance |
EXP |
TNFSF10 protein results in increased susceptibility to Atorvastatin |
CTD |
PMID:21910007 |
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NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475
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G |
TOMM20 |
translocase of outer mitochondrial membrane 20 |
increases expression multiple interactions |
ISO |
Atorvastatin results in increased expression of TOMM20 protein [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of TOMM20 protein |
CTD |
PMID:30511338 |
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NCBI chr 1:235,109,341...235,128,837
Ensembl chr 1:235,109,341...235,128,837
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G |
TP53 |
tumor protein p53 |
increases expression multiple interactions |
EXP ISO |
Atorvastatin results in increased expression of TP53 protein Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of TRP53 protein] |
CTD |
PMID:29630879 PMID:37121058 |
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NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
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G |
TRAF6 |
TNF receptor associated factor 6 |
multiple interactions |
EXP |
[Atorvastatin co-treated with Enalapril] results in decreased expression of TRAF6 mRNA; [Atorvastatin co-treated with Telmisartan] results in decreased expression of TRAF6 mRNA |
CTD |
PMID:20524934 |
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NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272
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G |
TUBB3 |
tubulin beta 3 class III |
increases expression |
ISO |
Atorvastatin results in increased expression of TUBB3 protein |
CTD |
PMID:15255259 |
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NCBI chr16:89,921,925...89,936,097
Ensembl chr16:89,921,392...89,938,761
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VCAM1 |
vascular cell adhesion molecule 1 |
decreases expression multiple interactions |
EXP ISO |
Atorvastatin results in decreased expression of VCAM1 mRNA; Atorvastatin results in decreased expression of VCAM1 protein Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of VCAM1 protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of VCAM1 protein] |
CTD |
PMID:17589825 PMID:17673219 PMID:22245985 PMID:25058445 |
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NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
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G |
VEGFD |
vascular endothelial growth factor D |
affects expression |
EXP |
Atorvastatin affects the expression of VEGFD mRNA |
CTD |
PMID:16410222 |
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NCBI chr X:15,345,596...15,384,413
Ensembl chr X:15,345,596...15,384,413
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G |
VIM |
vimentin |
multiple interactions |
ISO |
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of VIM protein] |
CTD |
PMID:34939712 |
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NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593
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G |
VWF |
von Willebrand factor |
increases expression |
EXP |
Atorvastatin results in increased expression of VWF protein |
CTD |
PMID:19171469 |
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NCBI chr12:5,948,877...6,124,670
Ensembl chr12:5,948,877...6,124,770
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G |
WT1 |
WT1 transcription factor |
multiple interactions |
ISO |
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of WT1 protein] |
CTD |
PMID:34939712 |
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NCBI chr11:32,387,775...32,435,539
Ensembl chr11:32,387,775...32,435,564
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G |
XIRP1 |
xin actin binding repeat containing 1 |
multiple interactions |
ISO |
[Buthionine Sulfoximine co-treated with Atorvastatin co-treated with Ciprofloxacin] results in increased expression of XIRP1 mRNA |
CTD |
PMID:29679711 |
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NCBI chr 3:39,183,215...39,192,595
Ensembl chr 3:39,183,210...39,192,596
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G |
BGLAP |
bone gamma-carboxyglutamate protein |
decreases expression |
EXP |
Calcium Carbonate results in decreased expression of BGLAP protein |
CTD |
PMID:2027271 |
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NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
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G |
CAPN1 |
calpain 1 |
increases activity |
EXP |
Calcium Carbonate analog results in increased activity of CAPN1 protein |
CTD |
PMID:24412303 |
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NCBI chr11:65,181,373...65,212,006
Ensembl chr11:65,180,566...65,212,006
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G |
CASP3 |
caspase 3 |
increases activity |
EXP |
Calcium Carbonate analog results in increased activity of CASP3 protein |
CTD |
PMID:24412303 |
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NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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G |
DDIT3 |
DNA damage inducible transcript 3 |
increases expression |
EXP |
Calcium Carbonate analog results in increased expression of DDIT3 |
CTD |
PMID:24412303 |
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NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
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G |
PTH |
parathyroid hormone |
affects expression decreases expression |
EXP |
Calcium Carbonate affects the expression of PTH protein Calcium Carbonate results in decreased expression of PTH protein |
CTD |
PMID:1752077 PMID:2027271 PMID:3826069 PMID:7891547 PMID:8481062 PMID:16006300 More...
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NCBI chr11:13,492,054...13,496,181
Ensembl chr11:13,492,054...13,496,181
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G |
PTHLH |
parathyroid hormone like hormone |
decreases expression |
EXP |
Calcium Carbonate results in decreased expression of PTHLH protein |
CTD |
PMID:16006300 |
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NCBI chr12:27,958,084...27,972,733
Ensembl chr12:27,958,084...27,972,733
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G |
SPP1 |
secreted phosphoprotein 1 |
decreases expression |
ISO |
Calcium Carbonate results in decreased expression of SPP1 protein |
CTD |
PMID:17977878 |
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NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
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G |
ADAM10 |
ADAM metallopeptidase domain 10 |
increases expression |
ISO |
Calcium Chloride results in increased expression of ADAM10 mRNA; Calcium Chloride results in increased expression of ADAM10 protein |
CTD |
PMID:20621845 |
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NCBI chr15:58,588,809...58,749,707
Ensembl chr15:58,588,809...58,749,791
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G |
ADAM17 |
ADAM metallopeptidase domain 17 |
increases expression |
ISO |
Calcium Chloride results in increased expression of ADAM17 mRNA; Calcium Chloride results in increased expression of ADAM17 protein |
CTD |
PMID:20621845 |
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NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732
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G |
ALPL |
alkaline phosphatase, biomineralization associated |
increases expression |
EXP |
Calcium Chloride results in increased expression of ALPL mRNA |
CTD |
PMID:25824407 |
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NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410
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G |
APOC3 |
apolipoprotein C3 |
increases expression |
EXP |
Calcium Chloride results in increased expression of APOC3 protein |
CTD |
PMID:25824407 |
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NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072
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G |
ATP5PF |
ATP synthase peripheral stalk subunit F6 |
increases expression |
EXP |
Calcium Chloride results in increased expression of ATP5PF protein |
CTD |
PMID:25824407 |
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NCBI chr21:25,724,500...25,735,653
Ensembl chr21:25,716,503...25,735,673
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G |
BAG4 |
BAG cochaperone 4 |
increases expression |
EXP |
Calcium Chloride results in increased expression of BAG4 protein |
CTD |
PMID:25824407 |
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NCBI chr 8:38,176,855...38,213,301
Ensembl chr 8:38,176,533...38,213,301
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G |
BGLAP |
bone gamma-carboxyglutamate protein |
increases expression |
EXP |
Calcium Chloride results in increased expression of BGLAP mRNA |
CTD |
PMID:25824407 |
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NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
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G |
BICD2 |
BICD cargo adaptor 2 |
increases expression |
EXP |
Calcium Chloride results in increased expression of BICD2 protein |
CTD |
PMID:25824407 |
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NCBI chr 9:92,711,363...92,764,833
Ensembl chr 9:92,711,363...92,764,833
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G |
CALM3 |
calmodulin 3 |
multiple interactions |
EXP |
Calcium Chloride inhibits the reaction [CALM3 protein binds to and results in decreased activity of UBE3B protein] |
CTD |
PMID:28003368 |
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NCBI chr19:46,601,074...46,610,782
Ensembl chr19:46,601,074...46,610,782
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G |
CASP3 |
caspase 3 |
multiple interactions increases cleavage |
ISO |
cordycepin inhibits the reaction [Calcium Chloride results in increased cleavage of CASP3 protein] |
CTD |
PMID:36731150 |
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NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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G |
CASP9 |
caspase 9 |
increases cleavage multiple interactions |
ISO |
Calcium Chloride results in increased cleavage of CASP9 protein cordycepin inhibits the reaction [Calcium Chloride results in increased cleavage of CASP9 protein] |
CTD |
PMID:36731150 |
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NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
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G |
CASR |
calcium sensing receptor |
multiple interactions increases activity |
EXP |
Calcium Chloride promotes the reaction [Calcium results in increased phosphorylation of CASR protein] Calcium Chloride results in increased activity of CASR protein |
CTD |
PMID:16316325 PMID:17376781 |
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NCBI chr 3:122,183,668...122,291,629
Ensembl chr 3:122,183,668...122,291,629
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G |
CCL2 |
C-C motif chemokine ligand 2 |
increases phosphorylation increases expression multiple interactions |
ISO |
Calcium Chloride results in increased phosphorylation of CCL2 protein Calcium Chloride results in increased expression of CCL2 mRNA; Calcium Chloride results in increased expression of CCL2 protein Quercetin inhibits the reaction [Calcium Chloride results in increased expression of CCL2 protein]; resveratrol inhibits the reaction [Calcium Chloride results in increased expression of CCL2 mRNA]; resveratrol inhibits the reaction [Calcium Chloride results in increased phosphorylation of CCL2 protein] |
CTD |
PMID:21530968 PMID:22728078 |
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NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
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G |
CCT6A |
chaperonin containing TCP1 subunit 6A |
decreases expression |
EXP |
Calcium Chloride results in decreased expression of CCT6A protein |
CTD |
PMID:25824407 |
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NCBI chr 7:56,051,765...56,063,989
Ensembl chr 7:56,051,685...56,063,989
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G |
CD68 |
CD68 molecule |
multiple interactions increases expression |
ISO |
resveratrol inhibits the reaction [Calcium Chloride results in increased expression of CD68 mRNA] |
CTD |
PMID:21530968 |
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NCBI chr17:7,579,638...7,582,111
Ensembl chr17:7,579,491...7,582,111
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G |
CDKN1B |
cyclin dependent kinase inhibitor 1B |
multiple interactions |
ISO |
Calcium Chloride inhibits the reaction [Azoxymethane results in decreased expression of CDKN1B protein] |
CTD |
PMID:12189186 |
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NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369
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G |
CDKN2A |
cyclin dependent kinase inhibitor 2A |
multiple interactions |
ISO |
Calcium Chloride inhibits the reaction [Azoxymethane results in decreased expression of CDKN2A mRNA]; Calcium Chloride inhibits the reaction [Azoxymethane results in decreased expression of CDKN2A protein] |
CTD |
PMID:12189186 |
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NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
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G |
CEBPA |
CCAAT enhancer binding protein alpha |
increases activity |
EXP |
Calcium Chloride results in increased activity of CEBPA protein |
CTD |
PMID:17214633 |
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NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534
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G |
CLEC3B |
C-type lectin domain family 3 member B |
increases expression |
EXP |
Calcium Chloride results in increased expression of CLEC3B protein |
CTD |
PMID:25824407 |
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NCBI chr 3:45,026,303...45,036,071
Ensembl chr 3:45,001,548...45,036,071
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G |
CLIC3 |
chloride intracellular channel 3 |
decreases expression |
EXP |
Calcium Chloride results in decreased expression of CLIC3 protein |
CTD |
PMID:25824407 |
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NCBI chr 9:136,994,608...136,996,568
Ensembl chr 9:136,994,608...136,996,568
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G |
CMTM6 |
CKLF like MARVEL transmembrane domain containing 6 |
increases expression |
EXP |
Calcium Chloride results in increased expression of CMTM6 protein |
CTD |
PMID:25824407 |
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NCBI chr 3:32,481,312...32,502,852
Ensembl chr 3:32,481,312...32,502,852
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G |
COL1A1 |
collagen type I alpha 1 chain |
increases expression |
EXP |
Calcium Chloride results in increased expression of COL1A1 mRNA |
CTD |
PMID:25824407 |
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NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
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G |
COL8A1 |
collagen type VIII alpha 1 chain |
increases expression |
EXP |
Calcium Chloride results in increased expression of COL8A1 protein |
CTD |
PMID:25824407 |
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NCBI chr 3:99,638,594...99,799,217
Ensembl chr 3:99,638,475...99,799,226
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G |
COPS3 |
COP9 signalosome subunit 3 |
increases expression |
EXP |
Calcium Chloride results in increased expression of COPS3 protein |
CTD |
PMID:25824407 |
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NCBI chr17:17,246,616...17,281,246
Ensembl chr17:17,246,616...17,281,273
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G |
CST3 |
cystatin C |
increases expression |
EXP |
Calcium Chloride results in increased expression of CST3 protein |
CTD |
PMID:25824407 |
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NCBI chr20:23,626,706...23,637,955
Ensembl chr20:23,626,706...23,638,473
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G |
CTHRC1 |
collagen triple helix repeat containing 1 |
decreases expression |
EXP |
Calcium Chloride results in decreased expression of CTHRC1 protein |
CTD |
PMID:25824407 |
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NCBI chr 8:103,371,538...103,382,989
Ensembl chr 8:103,371,538...103,382,989
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G |
CTSB |
cathepsin B |
increases expression multiple interactions |
ISO |
Calcium Chloride results in increased expression of CTSB protein Quercetin inhibits the reaction [Calcium Chloride results in increased expression of CTSB protein] |
CTD |
PMID:22728078 |
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NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533
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G |
CTSK |
cathepsin K |
increases expression multiple interactions |
ISO |
Calcium Chloride results in increased expression of CTSK protein Quercetin inhibits the reaction [Calcium Chloride results in increased expression of CTSK protein] |
CTD |
PMID:22728078 |
|
NCBI chr 1:150,796,208...150,808,260
Ensembl chr 1:150,794,880...150,809,577
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G |
DCN |
decorin |
decreases expression |
EXP |
Calcium Chloride results in decreased expression of DCN protein |
CTD |
PMID:25824407 |
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NCBI chr12:91,140,484...91,182,817
Ensembl chr12:91,140,484...91,183,217
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G |
DDX39B |
DExD-box helicase 39B |
increases expression |
EXP |
Calcium Chloride results in increased expression of DDX39B protein |
CTD |
PMID:25824407 |
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NCBI chr 6:31,530,226...31,542,003
Ensembl chr 6:31,530,219...31,542,448
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G |
EHD2 |
EH domain containing 2 |
increases expression |
EXP |
Calcium Chloride results in increased expression of EHD2 protein |
CTD |
PMID:25824407 |
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NCBI chr19:47,713,422...47,743,134
Ensembl chr19:47,713,422...47,743,134
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G |
F10 |
coagulation factor X |
multiple interactions |
EXP |
[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein; aspalathin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein]; nothofagin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein] |
CTD |
PMID:25325928 |
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NCBI chr13:113,122,799...113,149,529
Ensembl chr13:113,122,799...113,149,529
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G |
F11 |
coagulation factor XI |
multiple interactions |
EXP |
[F11 protein co-treated with Calcium Chloride] results in increased activity of F9 protein |
CTD |
PMID:6604052 |
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NCBI chr 4:186,266,189...186,289,681
Ensembl chr 4:186,266,189...186,289,681
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G |
F2 |
coagulation factor II, thrombin |
multiple interactions |
EXP |
[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein; aspalathin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein]; nothofagin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein] |
CTD |
PMID:25325928 |
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NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
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G |
F5 |
coagulation factor V |
multiple interactions |
EXP |
[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein; aspalathin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein]; nothofagin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein] |
CTD |
PMID:25325928 |
|
NCBI chr 1:169,511,951...169,586,481
Ensembl chr 1:169,511,951...169,586,588
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G |
F9 |
coagulation factor IX |
multiple interactions |
EXP |
[F11 protein co-treated with Calcium Chloride] results in increased activity of F9 protein |
CTD |
PMID:6604052 |
|
NCBI chr X:139,530,739...139,563,459
Ensembl chr X:139,530,739...139,563,459
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G |
FYN |
FYN proto-oncogene, Src family tyrosine kinase |
increases expression |
EXP |
Calcium Chloride results in increased expression of FYN protein |
CTD |
PMID:25824407 |
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NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452
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G |
GIT1 |
GIT ArfGAP 1 |
increases expression |
EXP |
Calcium Chloride results in increased expression of GIT1 protein |
CTD |
PMID:25824407 |
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NCBI chr17:29,573,475...29,589,648
Ensembl chr17:29,573,475...29,594,054
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G |
GNRH1 |
gonadotropin releasing hormone 1 |
multiple interactions |
ISO |
[manganese chloride co-treated with Calcium Chloride] results in increased secretion of GNRH1 protein |
CTD |
PMID:18603625 |
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NCBI chr 8:25,419,258...25,425,040
Ensembl chr 8:25,419,258...25,424,654
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G |
GPR89B |
G protein-coupled receptor 89B |
increases expression |
EXP |
Calcium Chloride results in increased expression of GPR89B protein |
CTD |
PMID:25824407 |
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NCBI chr 1:147,928,420...148,025,934
Ensembl chr 1:147,928,393...147,993,592 Ensembl chr 1:147,928,393...147,993,592 Ensembl chr 1:147,928,393...147,993,592
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G |
GPX1 |
glutathione peroxidase 1 |
multiple interactions increases expression |
ISO |
Quercetin inhibits the reaction [Calcium Chloride results in increased expression of GPX1 mRNA]; resveratrol inhibits the reaction [Calcium Chloride results in increased expression of GPX1 mRNA] |
CTD |
PMID:21530968 PMID:24337353 |
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NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
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G |
GPX3 |
glutathione peroxidase 3 |
multiple interactions increases expression |
ISO |
Quercetin inhibits the reaction [Calcium Chloride results in increased expression of GPX3 mRNA]; resveratrol inhibits the reaction [Calcium Chloride results in increased expression of GPX3 mRNA] |
CTD |
PMID:21530968 PMID:24337353 |
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NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988
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G |
HMOX1 |
heme oxygenase 1 |
multiple interactions |
EXP ISO |
Calcium Chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA] |
CTD |
PMID:21443188 |
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NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
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G |
HTRA1 |
HtrA serine peptidase 1 |
decreases expression |
EXP |
Calcium Chloride results in decreased expression of HTRA1 protein |
CTD |
PMID:25824407 |
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NCBI chr10:122,461,553...122,514,907
Ensembl chr10:122,458,551...122,514,907
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G |
ICAM1 |
intercellular adhesion molecule 1 |
increases expression multiple interactions |
ISO |
Calcium Chloride results in increased expression of ICAM1 mRNA resveratrol inhibits the reaction [Calcium Chloride results in increased expression of ICAM1 mRNA] |
CTD |
PMID:21530968 |
|
NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
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G |
IFT27 |
intraflagellar transport 27 |
increases expression |
EXP |
Calcium Chloride results in increased expression of IFT27 protein |
CTD |
PMID:25824407 |
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NCBI chr22:36,758,211...36,776,119
Ensembl chr22:36,758,202...36,776,256
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G |
IL1B |
interleukin 1 beta |
increases expression multiple interactions |
ISO |
Calcium Chloride results in increased expression of IL1B protein Quercetin inhibits the reaction [Calcium Chloride results in increased expression of IL1B protein] |
CTD |
PMID:22728078 PMID:36731150 |
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NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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G |
ITIH1 |
inter-alpha-trypsin inhibitor heavy chain 1 |
multiple interactions |
EXP |
Calcium Chloride promotes the reaction [ITIH1 protein binds to TNFAIP6 protein] |
CTD |
PMID:16768462 |
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NCBI chr 3:52,777,599...52,792,068
Ensembl chr 3:52,777,595...52,792,068
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G |
ITIH2 |
inter-alpha-trypsin inhibitor heavy chain 2 |
multiple interactions |
EXP |
Calcium Chloride promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] |
CTD |
PMID:16768462 |
|
NCBI chr10:7,703,316...7,749,520
Ensembl chr10:7,703,316...7,749,520
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G |
KLK8 |
kallikrein related peptidase 8 |
increases activity |
EXP |
Calcium Chloride results in increased activity of KLK8 protein |
CTD |
PMID:16800733 |
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NCBI chr19:50,996,008...51,001,604
Ensembl chr19:50,996,007...51,002,711
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G |
LASP1 |
LIM and SH3 protein 1 |
increases expression |
EXP |
Calcium Chloride results in increased expression of LASP1 protein |
CTD |
PMID:25824407 |
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NCBI chr17:38,870,058...38,921,770
Ensembl chr17:38,869,859...38,921,770
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G |
LRRFIP1 |
LRR binding FLII interacting protein 1 |
decreases expression |
EXP |
Calcium Chloride results in decreased expression of LRRFIP1 protein |
CTD |
PMID:25824407 |
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NCBI chr 2:237,627,587...237,781,643
Ensembl chr 2:237,627,587...237,813,682
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MAPK1 |
mitogen-activated protein kinase 1 |
increases phosphorylation multiple interactions |
ISO |
Calcium Chloride results in increased phosphorylation of MAPK1 protein [4-Aminopyridine co-treated with Calcium Chloride] results in increased phosphorylation of MAPK1 protein; typhaneoside inhibits the reaction [[4-Aminopyridine co-treated with Calcium Chloride] results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:21215118 PMID:33621091 |
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NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
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MAPK3 |
mitogen-activated protein kinase 3 |
increases expression multiple interactions increases phosphorylation |
EXP ISO |
Calcium Chloride results in increased expression of MAPK3 protein [4-Aminopyridine co-treated with Calcium Chloride] results in increased phosphorylation of MAPK3 protein; typhaneoside inhibits the reaction [[4-Aminopyridine co-treated with Calcium Chloride] results in increased phosphorylation of MAPK3 protein] Calcium Chloride results in increased phosphorylation of MAPK3 protein |
CTD |
PMID:21215118 PMID:25824407 PMID:33621091 |
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NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
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G |
MMP2 |
matrix metallopeptidase 2 |
increases expression increases activity multiple interactions |
ISO EXP |
Calcium Chloride results in increased expression of MMP2 mRNA; Calcium Chloride results in increased expression of MMP2 protein Calcium Chloride results in increased activity of MMP2 protein Quercetin inhibits the reaction [Calcium Chloride results in increased activity of MMP2 protein]; Quercetin inhibits the reaction [Calcium Chloride results in increased expression of MMP2 mRNA]; Quercetin inhibits the reaction [Calcium Chloride results in increased expression of MMP2 protein]; resveratrol inhibits the reaction [Calcium Chloride results in increased activity of MMP2 protein] Calcium Chloride inhibits the reaction [2,3-dihydroxybenzoic acid results in decreased activity of MMP2 protein]; Calcium Chloride inhibits the reaction [Deferoxamine results in decreased activity of MMP2 protein]; Calcium Chloride inhibits the reaction [Ferrichrome results in decreased activity of MMP2 protein]; Calcium Chloride inhibits the reaction [rhodotorulic acid results in decreased activity of MMP2 protein] |
CTD |
PMID:10086886 PMID:16159824 PMID:20621845 PMID:21530968 PMID:22728078 PMID:24337353 More...
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NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
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G |
MMP9 |
matrix metallopeptidase 9 |
increases expression increases activity multiple interactions |
ISO |
Calcium Chloride results in increased expression of MMP9 mRNA; Calcium Chloride results in increased expression of MMP9 protein Calcium Chloride results in increased activity of MMP9 protein Quercetin inhibits the reaction [Calcium Chloride results in increased activity of MMP9 protein]; Quercetin inhibits the reaction [Calcium Chloride results in increased expression of MMP9 mRNA]; Quercetin inhibits the reaction [Calcium Chloride results in increased expression of MMP9 protein]; resveratrol inhibits the reaction [Calcium Chloride results in increased activity of MMP9 protein] |
CTD |
PMID:20621845 PMID:21530968 PMID:22728078 PMID:24337353 |
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NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
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G |
MYC |
MYC proto-oncogene, bHLH transcription factor |
multiple interactions |
ISO |
Calcium Chloride inhibits the reaction [Azoxymethane results in increased expression of MYC mRNA]; Calcium Chloride inhibits the reaction [Azoxymethane results in increased expression of MYC protein] |
CTD |
PMID:12189186 |
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NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
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G |
NCF1 |
neutrophil cytosolic factor 1 |
increases expression multiple interactions |
ISO |
Calcium Chloride results in increased expression of NCF1 mRNA; Calcium Chloride results in increased expression of NCF1 protein Quercetin inhibits the reaction [Calcium Chloride results in increased expression of NCF1 mRNA]; Quercetin inhibits the reaction [Calcium Chloride results in increased expression of NCF1 protein] |
CTD |
PMID:24337353 |
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NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315
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G |
NOS1 |
nitric oxide synthase 1 |
multiple interactions |
ISO |
Calcium Chloride promotes the reaction [NOS1 protein results in increased reduction of Trinitrotoluene] |
CTD |
PMID:15223068 |
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NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
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G |
NOS2 |
nitric oxide synthase 2 |
increases expression multiple interactions |
ISO |
Calcium Chloride results in increased expression of NOS2 mRNA Quercetin inhibits the reaction [Calcium Chloride results in increased expression of NOS2 mRNA] |
CTD |
PMID:24337353 |
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NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
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G |
NT5C |
5', 3'-nucleotidase, cytosolic |
increases expression |
EXP |
Calcium Chloride results in increased expression of NT5C protein |
CTD |
PMID:25824407 |
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NCBI chr17:75,130,228...75,131,742
Ensembl chr17:75,130,225...75,131,757
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G |
NXN |
nucleoredoxin |
increases expression |
EXP |
Calcium Chloride results in increased expression of NXN protein |
CTD |
PMID:25824407 |
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NCBI chr17:799,310...979,776
Ensembl chr17:799,310...979,776
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G |
PON1 |
paraoxonase 1 |
multiple interactions |
EXP |
Calcium Chloride promotes the reaction [PON1 protein results in increased hydrolysis of Paraoxon] |
CTD |
PMID:16052486 |
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NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
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G |
POSTN |
periostin |
decreases expression |
EXP |
Calcium Chloride results in decreased expression of POSTN protein |
CTD |
PMID:25824407 |
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NCBI chr13:37,562,585...37,598,768
Ensembl chr13:37,562,583...37,598,844
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G |
POTEKP |
POTE ankyrin domain family member K, pseudogene |
increases expression |
EXP |
Calcium Chloride results in increased expression of POTEKP protein |
CTD |
PMID:25824407 |
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NCBI chr 2:131,592,042...131,626,429
Ensembl chr 2:131,591,752...131,628,147
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G |
PPID |
peptidylprolyl isomerase D |
increases expression |
EXP |
Calcium Chloride results in increased expression of PPID mRNA; Calcium Chloride results in increased expression of PPID protein |
CTD |
PMID:18614807 |
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NCBI chr 4:158,709,127...158,723,396
Ensembl chr 4:158,709,127...158,723,396
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G |
PSEN2 |
presenilin 2 |
increases expression |
EXP |
Calcium Chloride results in increased expression of PSEN2 protein |
CTD |
PMID:25824407 |
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NCBI chr 1:226,870,616...226,903,668
Ensembl chr 1:226,870,184...226,927,726
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G |
RAD50 |
RAD50 double strand break repair protein |
decreases expression |
EXP |
Calcium Chloride results in decreased expression of RAD50 protein |
CTD |
PMID:25824407 |
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NCBI chr 5:132,556,977...132,646,349
Ensembl chr 5:132,556,019...132,646,349
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G |
RECK |
reversion inducing cysteine rich protein with kazal motifs |
increases expression |
EXP |
Calcium Chloride results in increased expression of RECK protein |
CTD |
PMID:25824407 |
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NCBI chr 9:36,036,913...36,124,455
Ensembl chr 9:36,036,913...36,124,455
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G |
S100A13 |
S100 calcium binding protein A13 |
multiple interactions |
EXP |
[Calcium Chloride co-treated with cuprous chloride] binds to and affects the folding of S100A13 protein; Calcium Chloride binds to and affects the folding of S100A13 protein |
CTD |
PMID:16766622 |
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NCBI chr 1:153,618,799...153,634,361
Ensembl chr 1:153,618,787...153,631,360
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G |
S100A8 |
S100 calcium binding protein A8 |
increases expression |
EXP |
Calcium Chloride results in increased expression of S100A8 mRNA; Calcium Chloride results in increased expression of S100A8 protein |
CTD |
PMID:17214633 |
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NCBI chr 1:153,390,032...153,422,583
Ensembl chr 1:153,390,032...153,391,073
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G |
S100A9 |
S100 calcium binding protein A9 |
increases expression |
EXP |
Calcium Chloride results in increased expression of S100A9 mRNA; Calcium Chloride results in increased expression of S100A9 protein |
CTD |
PMID:17214633 |
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NCBI chr 1:153,357,854...153,361,023
Ensembl chr 1:153,357,854...153,361,023
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G |
SHC1 |
SHC adaptor protein 1 |
increases expression |
EXP |
Calcium Chloride results in increased expression of SHC1 protein |
CTD |
PMID:25824407 |
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NCBI chr 1:154,962,298...154,974,376
Ensembl chr 1:154,962,298...154,974,395
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G |
SOD2 |
superoxide dismutase 2 |
increases activity multiple interactions |
ISO |
Calcium Chloride results in increased activity of SOD2 protein Quercetin inhibits the reaction [Calcium Chloride results in increased activity of SOD2 protein] |
CTD |
PMID:24337353 |
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NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
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G |
STAT6 |
signal transducer and activator of transcription 6 |
decreases expression |
EXP |
Calcium Chloride results in decreased expression of STAT6 protein |
CTD |
PMID:25824407 |
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NCBI chr12:57,095,408...57,111,362
Ensembl chr12:57,095,408...57,132,139
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G |
SYN1 |
synapsin I |
multiple interactions |
ISO |
[4-Aminopyridine co-treated with Calcium Chloride] results in increased phosphorylation of SYN1 protein; typhaneoside inhibits the reaction [[4-Aminopyridine co-treated with Calcium Chloride] results in increased phosphorylation of SYN1 protein] |
CTD |
PMID:33621091 |
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NCBI chr X:47,571,901...47,619,857
Ensembl chr X:47,571,901...47,619,857
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G |
TGFB1 |
transforming growth factor beta 1 |
decreases expression |
EXP |
Calcium Chloride results in decreased expression of TGFB1 protein |
CTD |
PMID:25824407 |
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NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
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G |
TIMP1 |
TIMP metallopeptidase inhibitor 1 |
decreases expression multiple interactions |
ISO |
Calcium Chloride results in decreased expression of TIMP1 mRNA Quercetin inhibits the reaction [Calcium Chloride results in decreased expression of TIMP1 mRNA] |
CTD |
PMID:22728078 |
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NCBI chr X:47,582,436...47,586,789
Ensembl chr X:47,582,408...47,586,789
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G |
TNF |
tumor necrosis factor |
multiple interactions increases expression |
ISO EXP |
Quercetin inhibits the reaction [Calcium Chloride results in increased expression of TNF protein]; resveratrol inhibits the reaction [Calcium Chloride results in increased expression of TNF mRNA] cordycepin inhibits the reaction [Calcium Chloride results in increased expression of TNF protein] Calcium Chloride inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein] Calcium Chloride results in increased expression of TNF mRNA; Calcium Chloride results in increased expression of TNF protein |
CTD |
PMID:21530968 PMID:22728078 PMID:36416909 PMID:36731150 |
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NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
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G |
TNFAIP6 |
TNF alpha induced protein 6 |
multiple interactions |
EXP |
Calcium Chloride promotes the reaction [ITIH1 protein binds to TNFAIP6 protein]; Calcium Chloride promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] |
CTD |
PMID:16768462 |
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NCBI chr 2:151,357,592...151,381,340
Ensembl chr 2:151,357,592...151,380,046
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G |
TRPV1 |
transient receptor potential cation channel subfamily V member 1 |
multiple interactions increases activity |
ISO |
Calcium Chloride inhibits the reaction [resiniferatoxin affects the reaction [[Sodium Chloride co-treated with benzamil] results in increased activity of TRPV1 protein]]; Ionomycin promotes the reaction [Calcium Chloride inhibits the reaction [resiniferatoxin affects the reaction [[Sodium Chloride co-treated with benzamil] results in increased activity of TRPV1 protein]]] Ionomycin inhibits the reaction [Calcium Chloride results in increased activity of TRPV1 protein]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [Calcium Chloride results in increased activity of TRPV1 protein]; resiniferatoxin promotes the reaction [Calcium Chloride results in increased activity of TRPV1 protein] |
CTD |
PMID:19553475 |
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NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411
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G |
UBE3B |
ubiquitin protein ligase E3B |
multiple interactions |
EXP |
Calcium Chloride inhibits the reaction [CALM3 protein binds to and results in decreased activity of UBE3B protein] |
CTD |
PMID:28003368 |
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NCBI chr12:109,477,634...109,547,829
Ensembl chr12:109,477,402...109,536,705
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G |
UQCRFS1 |
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 |
decreases phosphorylation multiple interactions |
ISO |
Calcium Chloride results in decreased phosphorylation of UQCRFS1 protein [oxophenylarsine co-treated with Calcium Chloride] results in decreased phosphorylation of UQCRFS1 protein; [tert-Butylhydroperoxide co-treated with Calcium Chloride] results in decreased phosphorylation of UQCRFS1 protein; Cyclosporine inhibits the reaction [[oxophenylarsine co-treated with Calcium Chloride] results in decreased phosphorylation of UQCRFS1 protein]; Cyclosporine inhibits the reaction [[tert-Butylhydroperoxide co-treated with Calcium Chloride] results in decreased phosphorylation of UQCRFS1 protein] |
CTD |
PMID:16023995 |
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NCBI chr19:29,205,320...29,213,151
Ensembl chr19:29,205,320...29,213,151
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G |
VEGFA |
vascular endothelial growth factor A |
increases expression multiple interactions |
ISO |
Calcium Chloride results in increased expression of VEGFA mRNA resveratrol inhibits the reaction [Calcium Chloride results in increased expression of VEGFA mRNA] |
CTD |
PMID:21530968 |
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NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
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G |
ALPL |
alkaline phosphatase, biomineralization associated |
increases expression |
EXP |
Calcium Hydroxide results in increased expression of ALPL mRNA |
CTD |
PMID:22083529 |
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NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410
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G |
COL1A1 |
collagen type I alpha 1 chain |
increases expression |
EXP |
Calcium Hydroxide results in increased expression of COL1A1 mRNA |
CTD |
PMID:22083529 |
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NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
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G |
ESR1 |
estrogen receptor 1 |
increases expression |
EXP |
Calcium Hydroxide results in increased expression of ESR1 mRNA |
CTD |
PMID:22083529 |
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NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
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G |
POLG |
DNA polymerase gamma, catalytic subunit |
affects expression |
ISO |
Calcium Hydroxide affects the expression of POLG mRNA |
CTD |
PMID:30615914 |
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NCBI chr15:89,316,320...89,334,824
Ensembl chr15:89,305,198...89,334,861
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G |
POLG2 |
DNA polymerase gamma 2, accessory subunit |
affects expression |
ISO |
Calcium Hydroxide affects the expression of POLG2 mRNA |
CTD |
PMID:30615914 |
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NCBI chr17:64,477,785...64,497,054
Ensembl chr17:64,477,785...64,497,054
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G |
TFAM |
transcription factor A, mitochondrial |
affects expression |
ISO |
Calcium Hydroxide affects the expression of TFAM mRNA |
CTD |
PMID:30615914 |
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NCBI chr10:58,385,410...58,399,220
Ensembl chr10:58,385,345...58,399,220
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G |
TRPV1 |
transient receptor potential cation channel subfamily V member 1 |
increases expression |
EXP |
Calcium Hydroxide results in increased expression of TRPV1 mRNA |
CTD |
PMID:22083529 |
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NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411
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G |
HMBS |
hydroxymethylbilane synthase |
decreases activity |
ISO |
Calcium ion decreases activity of purified Hmbs protein |
RGD |
PMID:6732900 |
RGD:25394584 |
NCBI chr11:119,084,881...119,093,549
Ensembl chr11:119,084,866...119,093,834
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G |
BAX |
BCL2 associated X, apoptosis regulator |
increases expression multiple interactions |
EXP |
Calcium Oxalate results in increased expression of BAX protein SIRT1 protein inhibits the reaction [Calcium Oxalate results in increased expression of BAX protein] |
CTD |
PMID:34333021 |
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NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
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G |
BCL2 |
BCL2 apoptosis regulator |
decreases expression multiple interactions |
EXP |
Calcium Oxalate results in decreased expression of BCL2 protein SIRT1 protein inhibits the reaction [Calcium Oxalate results in decreased expression of BCL2 protein] |
CTD |
PMID:34333021 |
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NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
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G |
CASP3 |
caspase 3 |
multiple interactions increases cleavage |
EXP |
SIRT1 protein inhibits the reaction [Calcium Oxalate results in increased cleavage of CASP3 protein] |
CTD |
PMID:34333021 |
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NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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G |
CAT |
catalase |
multiple interactions decreases expression |
ISO |
2-aminoethyl diphenylborinate inhibits the reaction [Calcium Oxalate results in decreased expression of CAT protein] |
CTD |
PMID:37454925 |
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NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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G |
CCL2 |
C-C motif chemokine ligand 2 |
decreases expression multiple interactions |
ISO |
Calcium Oxalate results in decreased expression of CCL2 protein 2-aminoethyl diphenylborinate inhibits the reaction [Calcium Oxalate results in decreased expression of CCL2 protein]; [Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CCL2 mRNA; [Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CCL2 protein; Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CCL2 mRNA]; Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CCL2 protein] |
CTD |
PMID:37414240 PMID:37454925 |
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NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
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G |
CD44 |
CD44 molecule (IN blood group) |
multiple interactions decreases expression |
ISO |
2-aminoethyl diphenylborinate inhibits the reaction [Calcium Oxalate results in decreased expression of CD44 protein]; [Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CD44 mRNA; [Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CD44 protein; Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CD44 mRNA]; Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CD44 protein] |
CTD |
PMID:37414240 PMID:37454925 |
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NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402
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G |
CYBB |
cytochrome b-245 beta chain |
increases expression multiple interactions |
ISO |
Calcium Oxalate results in increased expression of NOX2 protein 2-aminoethyl diphenylborinate inhibits the reaction [Calcium Oxalate results in increased expression of NOX2 protein] |
CTD |
PMID:37454925 |
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NCBI chr X:37,780,059...37,813,461
Ensembl chr X:37,780,018...37,813,461
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G |
HDAC1 |
histone deacetylase 1 |
multiple interactions |
ISO |
[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of HDAC1 mRNA; Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of HDAC1 mRNA] |
CTD |
PMID:37414240 |
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NCBI chr 1:32,292,083...32,333,626
Ensembl chr 1:32,292,083...32,333,635
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G |
HDAC2 |
histone deacetylase 2 |
multiple interactions |
ISO |
[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of HDAC2 mRNA; Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of HDAC2 mRNA] |
CTD |
PMID:37414240 |
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NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308
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G |
HDAC3 |
histone deacetylase 3 |
multiple interactions |
ISO |
[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of HDAC3 mRNA; Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of HDAC3 mRNA] |
CTD |
PMID:37414240 |
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NCBI chr 5:141,620,881...141,636,849
Ensembl chr 5:141,620,876...141,636,849
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G |
HDAC8 |
histone deacetylase 8 |
multiple interactions |
ISO |
[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of HDAC8 mRNA; Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of HDAC8 mRNA] |
CTD |
PMID:37414240 |
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NCBI chr X:72,329,516...72,572,843
Ensembl chr X:72,329,516...72,573,101
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G |
HMOX1 |
heme oxygenase 1 |
multiple interactions increases expression |
EXP |
phenyl-N-tert-butylnitrone inhibits the reaction [Calcium Oxalate results in increased expression of HMOX1 protein] |
CTD |
PMID:34333021 |
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NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
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G |
ITPR1 |
inositol 1,4,5-trisphosphate receptor type 1 |
increases expression multiple interactions |
ISO |
Calcium Oxalate results in increased expression of ITPR1 protein Losartan inhibits the reaction [Calcium Oxalate results in increased expression of ITPR1 protein] |
CTD |
PMID:37454925 |
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NCBI chr 3:4,493,348...4,847,506
Ensembl chr 3:4,493,345...4,847,506
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G |
ITPR2 |
inositol 1,4,5-trisphosphate receptor type 2 |
increases expression multiple interactions |
ISO |
Calcium Oxalate results in increased expression of ITPR2 protein Losartan inhibits the reaction [Calcium Oxalate results in increased expression of ITPR2 protein] |
CTD |
PMID:37454925 |
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NCBI chr12:26,335,352...26,833,194
Ensembl chr12:26,335,352...26,833,194
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G |
ITPR3 |
inositol 1,4,5-trisphosphate receptor type 3 |
increases expression |
ISO |
Calcium Oxalate results in increased expression of ITPR3 protein |
CTD |
PMID:37454925 |
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NCBI chr 6:33,621,322...33,696,562
Ensembl chr 6:33,620,365...33,696,574
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G |
NOX4 |
NADPH oxidase 4 |
increases expression multiple interactions |
ISO |
Calcium Oxalate results in increased expression of NOX4 protein 2-aminoethyl diphenylborinate inhibits the reaction [Calcium Oxalate results in increased expression of NOX4 protein] |
CTD |
PMID:37454925 |
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NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187
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G |
SIRT1 |
sirtuin 1 |
multiple interactions decreases expression |
EXP |
phenyl-N-tert-butylnitrone inhibits the reaction [Calcium Oxalate results in decreased expression of SIRT1 protein]; SIRT1 protein inhibits the reaction [Calcium Oxalate results in decreased expression of BCL2 protein]; SIRT1 protein inhibits the reaction [Calcium Oxalate results in increased cleavage of CASP3 protein]; SIRT1 protein inhibits the reaction [Calcium Oxalate results in increased expression of BAX protein] |
CTD |
PMID:34333021 |
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NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
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G |
SOD1 |
superoxide dismutase 1 |
decreases expression multiple interactions |
ISO |
Calcium Oxalate results in decreased expression of SOD1 protein 2-aminoethyl diphenylborinate inhibits the reaction [Calcium Oxalate results in decreased expression of SOD1 protein] |
CTD |
PMID:37454925 |
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NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
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G |
SPP1 |
secreted phosphoprotein 1 |
decreases expression multiple interactions |
ISO |
Calcium Oxalate results in decreased expression of SPP1 protein 2-aminoethyl diphenylborinate inhibits the reaction [Calcium Oxalate results in decreased expression of SPP1 protein]; [Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of SPP1 mRNA; [Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of SPP1 protein; Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of SPP1 mRNA]; Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of SPP1 protein] |
CTD |
PMID:37414240 PMID:37454925 |
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NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
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G |
CXCL10 |
C-X-C motif chemokine ligand 10 |
increases expression |
EXP |
calcium phosphate results in increased expression of CXCL10 protein |
CTD |
PMID:14600836 |
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NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
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G |
CXCL12 |
C-X-C motif chemokine ligand 12 |
increases expression |
EXP |
calcium phosphate results in increased expression of CXCL12 protein |
CTD |
PMID:14600836 |
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NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493
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G |
ABCB1 |
ATP binding cassette subfamily B member 1 |
multiple interactions |
EXP |
Calcium deficiency inhibits the reaction [ABCB1 protein results in increased export of Xanthenes]; Calcium inhibits the reaction [Magnesium results in increased activity of ABCB1 protein] |
CTD |
PMID:2900677 PMID:25862123 |
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NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
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G |
ABCB11 |
ATP binding cassette subfamily B member 11 |
multiple interactions |
EXP |
Calcium deficiency inhibits the reaction [ABCB11 protein results in increased export of Taurocholic Acid] |
CTD |
PMID:25862123 |
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NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324
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G |
ABCC2 |
ATP binding cassette subfamily C member 2 |
multiple interactions |
EXP |
Calcium deficiency inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein] |
CTD |
PMID:25862123 |
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NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
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G |
ACO2 |
aconitase 2 |
increases activity multiple interactions |
ISO |
Calcium results in increased activity of ACO2 protein [Calcium results in increased activity of ACO2 protein] which results in increased reduction of thiazolyl blue; [Nicardipine results in decreased uptake of Calcium] which results in decreased activity of ACO2 protein |
CTD |
PMID:12548706 |
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NCBI chr22:41,469,117...41,528,974
Ensembl chr22:41,447,830...41,529,273
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G |
ACTB |
actin beta |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of ACTB mRNA |
CTD |
PMID:15913539 |
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NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902
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G |
ADCY5 |
adenylate cyclase 5 |
decreases activity increases response to substance |
EXP ISO |
Calcium results in decreased activity of ADCY5 protein ADCY5 protein results in increased susceptibility to Calcium |
CTD |
PMID:12065575 PMID:12869393 |
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NCBI chr 3:123,282,296...123,449,090
Ensembl chr 3:123,282,296...123,449,090
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G |
ADCY9 |
adenylate cyclase 9 |
multiple interactions |
EXP |
Calcium inhibits the reaction [Miconazole results in increased activity of ADCY9 protein]; Tacrolimus inhibits the reaction [Calcium inhibits the reaction [Miconazole results in increased activity of ADCY9 protein]] |
CTD |
PMID:30607468 |
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NCBI chr16:3,953,387...4,116,442
Ensembl chr16:3,953,387...4,116,442
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G |
ADCYAP1 |
adenylate cyclase activating polypeptide 1 |
increases abundance affects abundance multiple interactions |
ISO |
ADCYAP1 protein results in increased abundance of Calcium ADCYAP1 protein affects the abundance of Calcium Calcium affects the reaction [ADCYAP1 protein results in increased expression of SELENOT mRNA]; SELENOT protein affects the reaction [ADCYAP1 protein results in increased abundance of Calcium] |
CTD |
PMID:18198219 PMID:21039959 |
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NCBI chr18:904,411...912,172
Ensembl chr18:904,871...912,172
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G |
ADGRL1 |
adhesion G protein-coupled receptor L1 |
multiple interactions |
ISO |
[alpha-latrotoxin binds to ADGRL1 protein] which results in increased uptake of Calcium; [black widow spider venom binds to ADGRL1 protein] which results in increased uptake of Calcium |
CTD |
PMID:10026162 |
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NCBI chr19:14,147,743...14,206,169
Ensembl chr19:14,147,743...14,206,187
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G |
ADGRL2 |
adhesion G protein-coupled receptor L2 |
multiple interactions |
ISO |
[alpha-latrotoxin binds to ADGRL2 protein] which results in increased uptake of Calcium; [black widow spider venom binds to ADGRL2 protein] which results in increased uptake of Calcium |
CTD |
PMID:10026162 |
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NCBI chr 1:81,306,132...81,993,932
Ensembl chr 1:81,306,147...81,993,932
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G |
ADM |
adrenomedullin |
decreases expression |
EXP |
Calcium results in decreased expression of ADM mRNA |
CTD |
PMID:20682585 |
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NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397
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G |
ADRA1A |
adrenoceptor alpha 1A |
multiple interactions affects transport |
ISO EXP |
[Epinephrine binds to and results in increased activity of ADRA1A protein] which results in increased transport of Calcium; [Phenylephrine binds to and results in increased activity of ADRA1A protein] which results in increased transport of Calcium; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of EIF4EBP1 protein]; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of MTOR protein]; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of RPS6KB1 protein] 5-methylurapidil inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; [A 61603 results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Epinephrine binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Oxymetazoline binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium] ADRA1A protein affects the transport of Calcium |
CTD |
PMID:12935885 PMID:15306222 PMID:15639650 PMID:15672411 PMID:16498073 PMID:20030735 More...
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NCBI chr 8:26,748,150...26,867,379
Ensembl chr 8:26,748,150...26,867,278
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G |
ADRA1B |
adrenoceptor alpha 1B |
multiple interactions |
EXP |
[Epinephrine binds to and results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; [Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium] |
CTD |
PMID:15306222 PMID:16498073 PMID:20030735 |
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NCBI chr 5:159,865,086...159,989,205
Ensembl chr 5:159,865,080...159,973,012
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G |
ADRA1D |
adrenoceptor alpha 1D |
multiple interactions |
EXP |
[Epinephrine binds to and results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; [Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium] |
CTD |
PMID:15306222 PMID:20030735 |
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NCBI chr20:4,220,630...4,249,287
Ensembl chr20:4,220,630...4,249,287
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G |
ADRA2A |
adrenoceptor alpha 2A |
multiple interactions |
EXP |
[Epinephrine binds to and results in increased activity of ADRA2A protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA2A protein] which results in increased abundance of Calcium |
CTD |
PMID:20030735 |
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NCBI chr10:111,077,029...111,080,907
Ensembl chr10:111,077,029...111,080,907
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G |
ADRA2B |
adrenoceptor alpha 2B |
multiple interactions |
EXP |
[Epinephrine binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; [Oxymetazoline binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; [xylometazoline binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium |
CTD |
PMID:20030735 |
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NCBI chr 2:96,112,876...96,116,571
Ensembl chr 2:96,112,876...96,116,571
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G |
ADRA2C |
adrenoceptor alpha 2C |
multiple interactions |
EXP |
[Epinephrine binds to and results in increased activity of ADRA2C protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA2C protein] which results in increased abundance of Calcium |
CTD |
PMID:20030735 |
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NCBI chr 4:3,766,385...3,768,526
Ensembl chr 4:3,766,348...3,768,526
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G |
ADRB2 |
adrenoceptor beta 2 |
multiple interactions |
ISO EXP |
[Terbutaline binds to and results in increased activity of ADRB2 protein] which affects the abundance of Calcium [Benzo(a)pyrene binds to ADRB2 protein] which results in increased transport of Calcium; ADRB2 protein promotes the reaction [Benzo(a)pyrene results in increased transport of Calcium] |
CTD |
PMID:10372813 PMID:22167199 |
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NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623
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G |
AGO2 |
argonaute RISC catalytic component 2 |
multiple interactions |
ISO |
Calcium affects the reaction [PICK1 protein binds to AGO2 protein]; Calcium deficiency inhibits the reaction [Excitatory Amino Acid Agonists inhibits the reaction [PICK1 protein binds to AGO2 protein]] |
CTD |
PMID:28404816 |
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NCBI chr 8:140,520,156...140,642,313
Ensembl chr 8:140,520,156...140,635,633
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G |
AGT |
angiotensinogen |
increases uptake affects localization multiple interactions increases abundance |
EXP ISO |
AGT protein results in increased uptake of Calcium AGT protein affects the localization of Calcium 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [AGT protein affects the localization of Calcium]; bafilomycin A1 inhibits the reaction [AGT protein affects the localization of Calcium]; Heparin inhibits the reaction [AGT protein affects the localization of Calcium]; Losartan inhibits the reaction [AGT protein affects the localization of Calcium]; Saralasin inhibits the reaction [AGT protein affects the localization of Calcium]; Sirolimus inhibits the reaction [AGT protein affects the localization of Calcium]; xestospongin C inhibits the reaction [AGT protein affects the localization of Calcium] [AGT protein results in increased abundance of Calcium] which results in increased abundance of Reactive Oxygen Species Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein] benidipine inhibits the reaction [AGT protein results in increased uptake of Calcium]; Mibefradil inhibits the reaction [AGT protein results in increased uptake of Calcium] |
CTD |
PMID:10660688 PMID:18331727 PMID:18854758 PMID:21613610 |
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NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
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G |
AGTR1 |
angiotensin II receptor type 1 |
affects expression |
ISO |
Calcium affects the expression of AGTR1A mRNA |
CTD |
PMID:15913539 |
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NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008
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G |
AKAP1 |
A-kinase anchoring protein 1 |
affects expression |
ISO |
Calcium affects the expression of AKAP1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr17:57,085,246...57,121,344
Ensembl chr17:57,085,092...57,121,346
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G |
AKAP11 |
A-kinase anchoring protein 11 |
affects expression |
ISO |
Calcium affects the expression of AKAP11 mRNA |
CTD |
PMID:15913539 |
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NCBI chr13:42,271,477...42,323,261
Ensembl chr13:42,272,152...42,323,261
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G |
AKT1 |
AKT serine/threonine kinase 1 |
affects abundance affects expression multiple interactions affects response to substance |
EXP ISO |
AKT1 protein affects the abundance of Calcium Calcium affects the expression of AKT1 mRNA [Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein; Calcium affects the reaction [P2RY1 protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; CAMKK2 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; PDK1 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; PX-866 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; STO 609 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; W 7 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein] AKT1 protein affects the susceptibility to Calcium |
CTD |
PMID:15913539 PMID:16094411 PMID:16236484 PMID:28634229 |
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NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
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G |
ALDH2 |
aldehyde dehydrogenase 2 family member |
multiple interactions |
ISO EXP |
ALDH2 protein inhibits the reaction [Ethanol affects the abundance of Calcium] Calcium affects the reaction [ALDH2 gene SNP affects the abundance of Lead] |
CTD |
PMID:17590987 PMID:28212632 |
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NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
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G |
ALG2 |
ALG2 alpha-1,3/1,6-mannosyltransferase |
affects binding |
EXP |
Calcium binds to ALG2 protein |
CTD |
PMID:18997320 |
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NCBI chr 9:99,216,425...99,221,942
Ensembl chr 9:99,216,425...99,221,942
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G |
ALOX5 |
arachidonate 5-lipoxygenase |
multiple interactions |
EXP |
Calcium promotes the reaction [L 708714 binds to ALOX5 protein] |
CTD |
PMID:7577949 |
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NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119
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G |
ALPP |
alkaline phosphatase, placental |
affects binding |
EXP |
Calcium binds to ALPP protein |
CTD |
PMID:16815919 |
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NCBI chr 2:232,378,751...232,382,889
Ensembl chr 2:232,378,724...232,382,889
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G |
ANO1 |
anoctamin 1 |
increases activity multiple interactions |
EXP |
Calcium results in increased activity of ANO1 protein 9-phenanthrol inhibits the reaction [Calcium results in increased activity of ANO1 protein] |
CTD |
PMID:25573456 |
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NCBI chr11:69,965,997...70,189,530
Ensembl chr11:69,985,907...70,189,530
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G |
ANXA1 |
annexin A1 |
affects activity |
ISO |
Calcium affects the activity of ANXA1 protein |
CTD |
PMID:20655937 |
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NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393
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G |
ANXA5 |
annexin A5 |
multiple interactions |
EXP |
Calcium binds to and results in increased activity of ANXA5 protein; Calcium promotes the reaction [Phosphatidylserines binds to ANXA5 protein] |
CTD |
PMID:11578147 PMID:16076491 |
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NCBI chr 4:121,667,946...121,696,980
Ensembl chr 4:121,667,946...121,696,995
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G |
AOC1 |
amine oxidase copper containing 1 |
affects binding |
EXP |
AOC1 protein binds to Calcium |
CTD |
PMID:12072962 |
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NCBI chr 7:150,852,120...150,861,504
Ensembl chr 7:150,824,627...150,861,504
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G |
APOE |
apolipoprotein E |
affects abundance affects expression |
ISO |
APOE protein affects the abundance of Calcium Calcium affects the expression of APOE mRNA |
CTD |
PMID:15913539 PMID:17899169 |
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NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
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G |
APOM |
apolipoprotein M |
affects expression |
ISO |
Calcium affects the expression of APOM mRNA |
CTD |
PMID:15913539 |
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NCBI chr 6:31,652,404...31,658,210
Ensembl chr 6:31,652,416...31,658,210
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G |
APP |
amyloid beta precursor protein |
multiple interactions increases uptake affects abundance |
ISO |
2,4-Dinitrophenol affects the reaction [APP protein affects the abundance of Calcium]; 3-nitrophenol affects the reaction [APP protein affects the abundance of Calcium]; 4-anisidine affects the reaction [APP protein affects the abundance of Calcium] APP protein modified form results in increased uptake of Calcium; APP protein results in increased uptake of Calcium Calcium deficiency inhibits the reaction [APP protein modified form results in increased uptake of Calcium]; EDN3 protein inhibits the reaction [APP protein results in increased uptake of Calcium]; Flurbiprofen inhibits the reaction [APP protein results in increased uptake of Calcium]; Ibuprofen inhibits the reaction [APP protein results in increased uptake of Calcium]; Indomethacin inhibits the reaction [APP protein results in increased uptake of Calcium]; Nimodipine inhibits the reaction [APP protein results in increased uptake of Calcium]; Ruthenium Red inhibits the reaction [APP protein modified form results in increased uptake of Calcium]; Salicylates inhibits the reaction [APP protein results in increased uptake of Calcium]; sulindac sulfide inhibits the reaction [APP protein results in increased uptake of Calcium] |
CTD |
PMID:12383957 PMID:18648507 PMID:18949129 PMID:24457011 |
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NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128
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G |
ARRB2 |
arrestin beta 2 |
multiple interactions |
ISO |
ARRB2 protein affects the abundance of and affects the localization of Calcium ARRB2 promotes the reaction [carvedilol results in increased uptake of Calcium] |
CTD |
PMID:16210646 PMID:21078978 |
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NCBI chr17:4,710,632...4,721,497
Ensembl chr17:4,710,596...4,721,499
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G |
ATP1A1 |
ATPase Na+/K+ transporting subunit alpha 1 |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of ATP1A1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 1:116,373,244...116,404,774
Ensembl chr 1:116,372,668...116,410,261
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G |
ATP1B1 |
ATPase Na+/K+ transporting subunit beta 1 |
multiple interactions |
ISO |
Calcium affects the reaction [Ouabain results in increased expression of ATP1B1 mRNA] |
CTD |
PMID:11204457 |
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NCBI chr 1:169,106,690...169,132,719
Ensembl chr 1:169,105,697...169,310,992
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G |
ATP2A1 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 |
affects transport multiple interactions |
ISO |
ATP2A1 protein affects the transport of Calcium [Phenols results in decreased activity of ATP2A1 protein] which results in decreased transport of Calcium |
CTD |
PMID:11230109 PMID:18773882 |
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NCBI chr16:28,878,488...28,904,466
Ensembl chr16:28,878,405...28,904,466
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G |
ATP2A2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
affects abundance multiple interactions affects transport affects uptake affects export |
ISO EXP |
ATP2A2 protein affects the abundance of Calcium Calcium promotes the reaction [Clioquinol results in decreased expression of ATP2A2 mRNA]; Calcium promotes the reaction [Clioquinol results in decreased expression of ATP2A2 protein] ATP2A2 protein affects the transport of Calcium [[Phenylephrine results in increased activity of SLC9A1 protein] which results in increased transport of Calcium] which results in increased expression of ATP2A2 protein; [Phenylephrine results in decreased expression of ATP2A2 protein] which results in decreased transport of Calcium; [Thapsigargin results in decreased activity of ATP2A2 protein] which results in decreased transport of Calcium Calcium promotes the reaction [Clioquinol results in decreased expression of ATP2A2 mRNA]; Calcium promotes the reaction [Clioquinol results in decreased expression of ATP2A2 protein]; PPP3R1 gene mutant form inhibits the reaction [ATP2A2 protein affects the transport of Calcium] ATP2A2 protein alternative form affects the uptake of Calcium ATP2A2 protein alternative form affects the export of Calcium |
CTD |
PMID:11679415 PMID:16236312 PMID:17287366 PMID:19244478 PMID:19328205 PMID:19700627 PMID:33511738 More...
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NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093
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G |
ATP2B1 |
ATPase plasma membrane Ca2+ transporting 1 |
multiple interactions increases export |
EXP |
caloxin 1b1 inhibits the reaction [ATP2B1 protein results in increased export of Calcium] |
CTD |
PMID:16452157 |
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NCBI chr12:89,588,049...89,709,366
Ensembl chr12:89,588,049...89,709,366
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G |
ATP2B4 |
ATPase plasma membrane Ca2+ transporting 4 |
increases export multiple interactions |
EXP |
ATP2B4 protein results in increased export of Calcium caloxin 1b1 inhibits the reaction [ATP2B4 protein results in increased export of Calcium] |
CTD |
PMID:16452157 |
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NCBI chr 1:203,626,832...203,744,081
Ensembl chr 1:203,626,832...203,744,081
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G |
ATP8B1 |
ATPase phospholipid transporting 8B1 |
multiple interactions |
ISO |
Calcium inhibits the reaction [ATP8B1 protein results in increased transport of Phosphatidylserines] |
CTD |
PMID:11584374 |
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NCBI chr18:57,646,426...57,803,315
Ensembl chr18:57,646,426...57,803,315
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G |
AVP |
arginine vasopressin |
multiple interactions increases uptake increases abundance |
ISO |
1-Butanol inhibits the reaction [AVP protein results in increased abundance of Calcium]; 2-(4-amylcinnamoyl)amino-4-chlorobenzoic acid inhibits the reaction [AVP protein results in increased abundance of Calcium]; [[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; [[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein; [AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium; [AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium; AVP protein results in increased import of and results in increased abundance of Calcium; Carvedilol inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium]; Chromium affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; Chromium affects the reaction [INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; chromium tripicolinate affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; chromium tripicolinate affects the reaction [INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; INS1 protein affects the reaction [Chromium affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; INS1 protein affects the reaction [chromium tripicolinate affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; Nicardipine inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium]; Nifedipine inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium] |
CTD |
PMID:9446840 PMID:11356622 PMID:11553362 PMID:14711191 PMID:21039959 |
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NCBI chr20:3,082,556...3,084,724
Ensembl chr20:3,082,556...3,084,724
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G |
AVPR1A |
arginine vasopressin receptor 1A |
multiple interactions |
ISO |
[[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; [[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein; [AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium; [NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium; Carbachol promotes the reaction [[NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium]; Nicardipine inhibits the reaction [[NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium]; Nicardipine inhibits the reaction [Carbachol promotes the reaction [[NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium]] |
CTD |
PMID:11553362 PMID:12646291 |
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NCBI chr12:63,142,759...63,151,201
Ensembl chr12:63,142,759...63,151,201
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G |
AVPR2 |
arginine vasopressin receptor 2 |
affects expression |
ISO |
Calcium affects the expression of AVPR2 mRNA |
CTD |
PMID:15913539 |
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NCBI chr X:153,902,625...153,907,166
Ensembl chr X:153,902,531...153,907,166
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G |
AXIN1 |
axin 1 |
affects expression |
ISO |
Calcium affects the expression of AXIN1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr16:287,440...352,723
Ensembl chr16:287,440...352,723
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G |
BAD |
BCL2 associated agonist of cell death |
affects expression |
ISO |
Calcium affects the expression of BAD mRNA |
CTD |
PMID:15913539 |
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NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
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G |
BDKRB1 |
bradykinin receptor B1 |
multiple interactions |
EXP ISO |
2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [[kallidin, des-Arg(10)- results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]; [kallidin, des-Arg(10)- results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium; Sodium affects the reaction [[kallidin, des-Arg(10)- results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium] [kallidin, des-Arg(10)- binds to and results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium; bradykinin, Lys-Leu(8)-desArg(9)- inhibits the reaction [[kallidin, des-Arg(10)- binds to and results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]; Indomethacin inhibits the reaction [[kallidin, des-Arg(10)- binds to and results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium] |
CTD |
PMID:15703175 PMID:22554775 |
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NCBI chr14:96,256,210...96,264,763
Ensembl chr14:96,256,210...96,268,967
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G |
BDKRB2 |
bradykinin receptor B2 |
multiple interactions |
EXP ISO |
BDKRB2 protein affects the reaction [KNG1 protein affects the abundance of Calcium] BDKRB2 protein affects the reaction [pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]] |
CTD |
PMID:16473424 PMID:18054572 |
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NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166
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G |
BDNF |
brain derived neurotrophic factor |
multiple interactions increases transport |
ISO EXP |
[Cadmium results in decreased transport of Calcium] inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein]; Calcium affects the reaction [Oxygen deficiency results in increased secretion of BDNF protein] BDNF protein results in increased transport of Calcium 3,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]; 3,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide promotes the reaction [Tetrodotoxin inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]]; Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]; Tetrodotoxin inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]] |
CTD |
PMID:16553631 PMID:26095976 |
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NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
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G |
BEST1 |
bestrophin 1 |
increases activity multiple interactions |
ISO EXP |
Calcium results in increased activity of BEST1 protein [PAR-1-activating peptide results in increased abundance of Calcium] which results in increased activity of BEST1 protein |
CTD |
PMID:19828819 PMID:25573456 |
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NCBI chr11:61,949,821...61,965,515
Ensembl chr11:61,950,063...61,965,515
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G |
BMP4 |
bone morphogenetic protein 4 |
affects expression multiple interactions |
ISO EXP |
Calcium affects the expression of BMP4 mRNA [Calcium binds to MGP protein] which binds to and results in decreased activity of BMP4 protein; [Edetic Acid inhibits the reaction [Calcium binds to MGP protein]] inhibits the reaction [MGP protein binds to BMP4 protein] |
CTD |
PMID:15913539 PMID:18369157 |
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NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
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G |
BTK |
Bruton tyrosine kinase |
affects transport |
ISO |
BTK protein affects the transport of Calcium |
CTD |
PMID:12848851 |
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NCBI chr X:101,349,450...101,390,796
Ensembl chr X:101,349,338...101,390,796
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G |
C5 |
complement C5 |
multiple interactions |
EXP ISO |
[C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium; resveratrol inhibits the reaction [[C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium] |
CTD |
PMID:19284563 PMID:19346296 |
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NCBI chr 9:120,952,335...121,074,865
Ensembl chr 9:120,932,987...121,075,195
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G |
CA4 |
carbonic anhydrase 4 |
affects expression |
ISO |
Calcium affects the expression of CA4 mRNA |
CTD |
PMID:15913539 |
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NCBI chr17:60,149,973...60,179,021
Ensembl chr17:60,149,942...60,170,899
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G |
CACNA1A |
calcium voltage-gated channel subunit alpha1 A |
increases transport multiple interactions |
ISO |
CACNA1A protein results in increased transport of Calcium Allethrins inhibits the reaction [CACNA1A protein results in increased transport of Calcium] |
CTD |
PMID:14634047 |
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NCBI chr19:13,206,442...13,506,479
Ensembl chr19:13,206,442...13,633,025
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G |
CACNA1B |
calcium voltage-gated channel subunit alpha1 B |
multiple interactions decreases uptake increases transport |
ISO |
decamethrin inhibits the reaction [CACNA1B protein results in increased transport of Calcium]; decamethrin promotes the reaction [CACNA1B gene mutant form results in increased transport of Calcium] CACNA1B protein alternative form results in decreased uptake of Calcium |
CTD |
PMID:18383452 PMID:22891239 |
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NCBI chr 9:137,877,782...138,124,619
Ensembl chr 9:137,877,782...138,124,624
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G |
CACNA1C |
calcium voltage-gated channel subunit alpha1 C |
increases transport multiple interactions |
EXP ISO |
CACNA1C protein results in increased transport of Calcium [CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium; [CACNA2D4 protein binds to CACNA1C protein binds to CACNB3 protein] which results in increased transport of Calcium; CACNA2D4 protein promotes the reaction [[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium] Allethrins inhibits the reaction [CACNA1C protein results in increased transport of Calcium] |
CTD |
PMID:12181424 PMID:14634047 PMID:15299022 |
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NCBI chr12:1,970,780...2,697,950
Ensembl chr12:1,970,772...2,697,950
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G |
CACNA1D |
calcium voltage-gated channel subunit alpha1 D |
affects transport multiple interactions |
ISO |
CACNA1D protein affects the transport of Calcium CACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Calcium] [CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium; [CACNA1D protein results in increased uptake of Calcium] which affects the localization of SLC2A2 protein; [CACNA1D protein results in increased uptake of Calcium] which results in increased phosphorylation of MYL9 protein; CACNA2D1 protein promotes the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]; gabapentin affects the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]; SLC5A1 protein affects the reaction [CACNA1D protein results in increased uptake of Calcium] |
CTD |
PMID:15357422 PMID:17272349 PMID:19796812 PMID:27798183 |
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NCBI chr 3:53,494,611...53,813,733
Ensembl chr 3:53,328,963...53,813,733
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G |
CACNA1E |
calcium voltage-gated channel subunit alpha1 E |
increases transport multiple interactions |
EXP ISO |
CACNA1E protein results in increased transport of Calcium Calcium inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]] Cadmium inhibits the reaction [CACNA1E protein results in increased transport of Calcium]; Nickel inhibits the reaction [CACNA1E protein results in increased transport of Calcium] |
CTD |
PMID:10627594 PMID:10669483 PMID:12663092 |
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NCBI chr 1:181,317,699...181,808,084
Ensembl chr 1:181,317,690...181,813,262
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G |
CACNA1F |
calcium voltage-gated channel subunit alpha1 F |
increases transport |
ISO |
CACNA1F protein results in increased transport of Calcium |
CTD |
PMID:14744918 |
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NCBI chr X:49,205,063...49,233,340
Ensembl chr X:49,205,063...49,233,371
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G |
CACNA1G |
calcium voltage-gated channel subunit alpha1 G |
increases transport multiple interactions |
ISO |
CACNA1G protein results in increased transport of Calcium Allethrins inhibits the reaction [CACNA1G protein results in increased transport of Calcium] CACNG2 protein affects the reaction [CACNA1G protein results in increased transport of Calcium]; CACNG4 protein affects the reaction [CACNA1G protein results in increased transport of Calcium]; CACNG5 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] |
CTD |
PMID:10734232 PMID:11073957 PMID:14634047 |
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NCBI chr17:50,560,715...50,627,474
Ensembl chr17:50,560,715...50,627,474
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G |
CACNA1H |
calcium voltage-gated channel subunit alpha1 H |
increases transport multiple interactions |
EXP ISO |
CACNA1H protein results in increased transport of Calcium Amiloride inhibits the reaction [CACNA1H protein results in increased transport of Calcium]; Nickel inhibits the reaction [CACNA1H protein results in increased transport of Calcium] Amiloride inhibits the reaction [CACNA1H protein results in increased transport of Calcium]; Mibefradil inhibits the reaction [CACNA1H protein results in increased transport of Calcium]; Nickel inhibits the reaction [CACNA1H protein results in increased transport of Calcium] |
CTD |
PMID:9930755 PMID:11073957 PMID:11897840 |
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NCBI chr16:1,153,106...1,221,768
Ensembl chr16:1,153,103...1,224,169
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G |
CACNA1I |
calcium voltage-gated channel subunit alpha1 I |
increases transport |
ISO |
CACNA1I protein results in increased transport of Calcium |
CTD |
PMID:11073957 |
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NCBI chr22:39,570,753...39,689,735
Ensembl chr22:39,570,753...39,689,735
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G |
CACNA2D1 |
calcium voltage-gated channel auxiliary subunit alpha2delta 1 |
multiple interactions increases transport |
ISO |
[gabapentin results in decreased activity of CACNA2D1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]; CACNA2D1 protein affects the reaction [Potassium Chloride results in increased transport of Calcium] CACNA2D1 protein promotes the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium] CACNA2D1 protein results in increased transport of Calcium |
CTD |
PMID:15474003 PMID:17442347 PMID:17881535 PMID:19796812 |
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NCBI chr 7:81,946,444...82,443,956
Ensembl chr 7:81,946,444...82,443,956
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G |
CACNA2D2 |
calcium voltage-gated channel auxiliary subunit alpha2delta 2 |
affects transport multiple interactions |
ISO |
CACNA2D2 protein affects the transport of Calcium CACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Calcium] |
CTD |
PMID:14660671 PMID:27798183 |
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NCBI chr 3:50,362,613...50,504,244
Ensembl chr 3:50,362,613...50,504,244
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G |
CACNA2D4 |
calcium voltage-gated channel auxiliary subunit alpha2delta 4 |
multiple interactions |
EXP |
[CACNA2D4 protein binds to CACNA1C protein binds to CACNB3 protein] which results in increased transport of Calcium; CACNA2D4 protein promotes the reaction [[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium] |
CTD |
PMID:12181424 |
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NCBI chr12:1,791,963...1,918,652
Ensembl chr12:1,791,963...1,918,666
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G |
CACNB3 |
calcium voltage-gated channel auxiliary subunit beta 3 |
multiple interactions |
EXP ISO |
[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium; [CACNA2D4 protein binds to CACNA1C protein binds to CACNB3 protein] which results in increased transport of Calcium; CACNA2D4 protein promotes the reaction [[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium] [CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium; CACNA2D1 protein promotes the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]; Gabapentin affects the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium] |
CTD |
PMID:12181424 PMID:19796812 |
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NCBI chr12:48,814,480...48,828,941
Ensembl chr12:48,813,794...48,828,941
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G |
CACNG2 |
calcium voltage-gated channel auxiliary subunit gamma 2 |
multiple interactions |
ISO |
CACNG2 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] |
CTD |
PMID:10734232 |
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NCBI chr22:36,560,857...36,703,752
Ensembl chr22:36,560,857...36,703,752
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G |
CACNG4 |
calcium voltage-gated channel auxiliary subunit gamma 4 |
multiple interactions |
ISO |
CACNG4 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] |
CTD |
PMID:10734232 |
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NCBI chr17:66,964,707...67,033,398
Ensembl chr17:66,964,707...67,033,398
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G |
CACNG5 |
calcium voltage-gated channel auxiliary subunit gamma 5 |
multiple interactions |
ISO |
CACNG5 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] |
CTD |
PMID:10734232 |
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NCBI chr17:66,835,117...66,894,751
Ensembl chr17:66,835,117...66,894,751
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G |
CALB1 |
calbindin 1 |
affects expression |
ISO |
Calcium affects the expression of CALB1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 8:90,058,608...90,082,879
Ensembl chr 8:90,058,608...90,095,475
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G |
CALCA |
calcitonin related polypeptide alpha |
multiple interactions increases expression |
ISO EXP |
rimabotulinumtoxinB inhibits the reaction [[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein]; rimabotulinumtoxinB inhibits the reaction [[Potassium co-treated with Calcium] results in increased secretion of CALCA protein] Calcium promotes the reaction [Lipopolysaccharides results in increased expression of CALCA mRNA] Calcium results in increased expression of CALCA mRNA Calcium results in increased expression of CALCA protein [Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein; [KNG1 protein alternative form co-treated with Calcium] results in increased secretion of CALCA protein; [Potassium co-treated with Calcium] results in increased secretion of CALCA protein; [Sumatriptan results in increased abundance of Calcium] inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA]; botulinum toxin type D inhibits the reaction [[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein]; botulinum toxin type D inhibits the reaction [[Potassium co-treated with Calcium] results in increased secretion of CALCA protein]; Botulinum Toxins, Type A inhibits the reaction [[Potassium co-treated with Calcium] results in increased secretion of CALCA protein]; Calcium affects the reaction [Capsaicin inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Calcium affects the reaction [Capsaicin inhibits the reaction [mustard oil results in increased secretion of CALCA protein]]; Calcium affects the reaction [mustard oil inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Calcium deficiency inhibits the reaction [safranal results in increased secretion of CALCA protein]; Calcium inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA] |
CTD |
PMID:2470235 PMID:12574409 PMID:17590514 PMID:17666428 PMID:20682585 PMID:30636360 More...
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NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354
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G |
CALM1 |
calmodulin 1 |
multiple interactions affects binding |
EXP ISO |
Calcium affects the folding of [CALM1 protein binds to RYR1 protein modified form]; Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein] Calcium binds to CALM1 protein [Calcium binds to CALM1 protein] promotes the reaction [NOS1 protein results in increased chemical synthesis of Nitric Oxide]; [Calcium binds to CALM1 protein] which binds to and affects the folding of and results in increased activity of NOS1 protein; Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]; Calcium affects the reaction [CALM1 protein modified form binds to and affects the activity of RYR1 protein]; Calcium binds to and affects the folding of CALM1 protein |
CTD |
PMID:15381065 PMID:15628869 PMID:17098364 |
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NCBI chr14:90,396,502...90,408,268
Ensembl chr14:90,396,502...90,408,268
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G |
CALR |
calreticulin |
affects response to substance multiple interactions |
ISO |
CALR protein affects the susceptibility to Calcium CALR protein promotes the reaction [KNG1 protein modified form results in increased abundance of Calcium] |
CTD |
PMID:7961812 |
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NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489
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G |
CAMK2D |
calcium/calmodulin dependent protein kinase II delta |
affects expression multiple interactions |
ISO EXP |
Calcium affects the expression of CAMK2D mRNA [Ionomycin co-treated with Calcium co-treated with CAMK2D protein] results in increased activity of TRPM4 protein |
CTD |
PMID:15913539 PMID:33392831 |
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NCBI chr 4:113,451,032...113,761,738
Ensembl chr 4:113,418,054...113,761,927
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G |
CAMKK2 |
calcium/calmodulin dependent protein kinase kinase 2 |
multiple interactions |
EXP |
CAMKK2 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:28634229 |
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NCBI chr12:121,237,692...121,297,819
Ensembl chr12:121,237,675...121,298,308
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G |
CAPN1 |
calpain 1 |
multiple interactions increases cleavage increases activity |
EXP ISO |
[Caffeine co-treated with Alprazolam] promotes the reaction [Calcium results in increased activity of CAPN1 protein]; [Calcium co-treated with CAPN1 protein] results in increased degradation of TP73 protein modified form; [sodium arsenite results in increased abundance of Arsenic] promotes the reaction [[Calcium results in increased cleavage of CAPN1 protein] which results in increased degradation of CAPN1 protein] calpain inhibitor III inhibits the reaction [Calcium results in increased activity of CAPN1 protein] |
CTD |
PMID:19490937 PMID:21516125 PMID:21985864 PMID:31398423 |
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NCBI chr11:65,181,373...65,212,006
Ensembl chr11:65,180,566...65,212,006
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G |
CASP3 |
caspase 3 |
multiple interactions |
ISO EXP |
[Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in increased expression of CASP3 mRNA]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in increased expression of CASP3 mRNA]; Calcium affects the reaction [sodium arsenite results in increased expression of CASP3 mRNA] Calcium deficiency inhibits the reaction [Dasatinib results in increased activity of CASP3 protein]; Calcium deficiency inhibits the reaction [Ionomycin results in increased activity of CASP3 protein] |
CTD |
PMID:24184500 PMID:29803841 |
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NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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G |
CASP9 |
caspase 9 |
multiple interactions |
ISO |
[Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in increased expression of CASP9 mRNA]]; Calcium affects the reaction [sodium arsenite results in increased expression of CASP9 mRNA] |
CTD |
PMID:24184500 |
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NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
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G |
CASR |
calcium sensing receptor |
increases phosphorylation multiple interactions increases uptake increases activity affects expression decreases response to substance increases response to substance |
EXP ISO |
Calcium results in increased phosphorylation of CASR protein [Aluminum binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Calcium binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Calcium binds to and results in increased activity of CASR protein] which results in increased abundance of Inositol Phosphates; [Gadolinium binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Magnesium binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Neomycin binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; Calcium binds to and results in increased activity of CASR protein; Gadolinium inhibits the reaction [Calcium binds to and results in increased activity of CASR protein] CASR protein results in increased uptake of Calcium Calcium results in increased activity of CASR protein 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [CASR protein results in increased uptake of Calcium]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [CASR protein results in increased uptake of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]; 2-aminoethoxydiphenyl borate inhibits the reaction [CASR protein results in increased uptake of Calcium]; [2-quinoxaline-carboxamide-N-adamantan-1-yl binds to and results in decreased activity of CASR protein] inhibits the reaction [Nickel results in increased abundance of Calcium]; [Calcium binds to and results in increased activity of CASR protein] which results in increased uptake of Calcium; [CASR protein mutant form results in increased susceptibility to Calcium] which results in increased abundance of Inositol 1,4,5-Trisphosphate; [Spermine binds to and results in increased activity of CASR protein] which results in increased uptake of Calcium; bisindolylmaleimide I inhibits the reaction [NPS R-467 promotes the reaction [Calcium results in increased phosphorylation of CASR protein]]; Calcium Chloride promotes the reaction [Calcium results in increased phosphorylation of CASR protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of WNT5A protein]; CASR protein affects the reaction [Nickel results in increased abundance of Calcium]; CASR protein promotes the reaction [TRPC6 protein results in increased uptake of Calcium]; chelerythrine inhibits the reaction [CASR protein results in increased uptake of Calcium]; Flufenamic Acid promotes the reaction [CASR protein results in increased uptake of Calcium]; Lanthanum inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]; Lanthanum inhibits the reaction [CASR protein results in increased uptake of Calcium]; methyl-beta-cyclodextrin inhibits the reaction [CASR protein results in increased uptake of Calcium]; N-(2-chlorophenylpropyl)-1-(3-methoxyphenyl)ethylamine affects the reaction [CASR gene mutant form results in increased susceptibility to Calcium]; N-(2-chlorophenylpropyl)-1-(3-methoxyphenyl)ethylamine promotes the reaction [CASR protein results in increased susceptibility to Calcium]; NPS R-467 promotes the reaction [Calcium results in increased phosphorylation of CASR protein]; Pertussis Toxin inhibits the reaction [CASR protein results in increased uptake of Calcium] Calcium affects the expression of CASR mRNA; Calcium affects the expression of CASR protein CASR protein mutant form results in decreased susceptibility to Calcium CASR gene mutant form results in increased susceptibility to Calcium; CASR protein mutant form results in increased susceptibility to Calcium |
CTD |
PMID:7874174 PMID:9011580 PMID:10231437 PMID:11071898 PMID:11089548 PMID:11701698 PMID:15788476 PMID:17041782 PMID:17376781 PMID:19781536 PMID:21562303 PMID:24658506 More...
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NCBI chr 3:122,183,668...122,291,629
Ensembl chr 3:122,183,668...122,291,629
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G |
CAT |
catalase |
multiple interactions |
EXP ISO |
CAT protein inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; CAT protein inhibits the reaction [Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]] [Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in decreased activity of CAT protein]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in decreased activity of CAT protein]; [Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of CAT protein]; Calcium affects the reaction [sodium arsenite results in decreased activity of CAT protein] |
CTD |
PMID:21127073 PMID:22534743 PMID:24184500 |
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NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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G |
CAV1 |
caveolin 1 |
affects transport |
ISO |
CAV1 protein affects the transport of Calcium |
CTD |
PMID:16428350 |
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NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179
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G |
CAV3 |
caveolin 3 |
multiple interactions |
EXP |
CAV3 protein affects the reaction [Potassium Chloride results in increased uptake of Calcium] |
CTD |
PMID:21294223 |
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NCBI chr 3:8,733,802...8,746,758
Ensembl chr 3:8,733,802...8,841,808
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G |
CBFB |
core-binding factor subunit beta |
affects expression |
ISO |
Calcium affects the expression of CBFB mRNA |
CTD |
PMID:15913539 |
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NCBI chr16:67,029,149...67,101,058
Ensembl chr16:67,028,984...67,101,058
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G |
CCL11 |
C-C motif chemokine ligand 11 |
increases uptake |
EXP |
CCL11 protein results in increased uptake of Calcium |
CTD |
PMID:10984371 |
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NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334
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G |
CCL13 |
C-C motif chemokine ligand 13 |
increases uptake |
EXP |
CCL13 protein results in increased uptake of Calcium |
CTD |
PMID:10984371 |
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NCBI chr17:34,356,480...34,358,610
Ensembl chr17:34,356,480...34,358,610
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G |
CCL2 |
C-C motif chemokine ligand 2 |
multiple interactions increases abundance increases uptake |
EXP |
montelukast inhibits the reaction [CCL2 protein results in increased abundance of Calcium]; Piperidines analog inhibits the reaction [CCL2 protein results in increased uptake of Calcium]; Resveratrol inhibits the reaction [CCL2 protein affects the localization of Calcium] |
CTD |
PMID:10843593 PMID:10984371 PMID:16212921 PMID:16771778 |
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NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
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G |
CCL3 |
C-C motif chemokine ligand 3 |
multiple interactions |
EXP |
resveratrol inhibits the reaction [CCL3 protein affects the localization of Calcium] |
CTD |
PMID:16212921 |
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NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
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G |
CCL5 |
C-C motif chemokine ligand 5 |
increases uptake |
EXP |
CCL5 protein results in increased uptake of Calcium |
CTD |
PMID:10984371 |
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NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
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G |
CCL7 |
C-C motif chemokine ligand 7 |
increases uptake multiple interactions |
EXP |
CCL7 protein results in increased uptake of Calcium Piperidines analog inhibits the reaction [CCL7 protein results in increased uptake of Calcium] |
CTD |
PMID:10843593 PMID:10984371 |
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NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242
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G |
CCND1 |
cyclin D1 |
affects expression increases expression |
ISO EXP |
Calcium affects the expression of CCND1 mRNA Calcium results in increased expression of CCND1 mRNA |
CTD |
PMID:15913539 PMID:24658506 |
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NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
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G |
CCR10 |
C-C motif chemokine receptor 10 |
affects abundance |
EXP |
CCR10 protein affects the abundance of Calcium |
CTD |
PMID:12055238 |
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NCBI chr17:42,678,889...42,681,843
Ensembl chr17:42,678,889...42,683,917
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G |
CCR4 |
C-C motif chemokine receptor 4 |
affects abundance |
EXP |
CCR4 protein affects the abundance of Calcium |
CTD |
PMID:12055238 |
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NCBI chr 3:32,951,644...32,956,349
Ensembl chr 3:32,951,644...32,956,349
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G |
CCR8 |
C-C motif chemokine receptor 8 |
affects abundance |
EXP |
CCR8 protein affects the abundance of Calcium |
CTD |
PMID:12055238 |
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NCBI chr 3:39,329,709...39,333,680
Ensembl chr 3:39,329,709...39,333,680
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G |
CCR9 |
C-C motif chemokine receptor 9 |
affects abundance |
EXP |
CCR9 protein affects the abundance of Calcium |
CTD |
PMID:12055238 |
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NCBI chr 3:45,886,064...45,903,174
Ensembl chr 3:45,884,425...45,903,174
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G |
CD28 |
CD28 molecule |
multiple interactions increases abundance |
EXP |
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [CD28 protein results in increased abundance of Calcium]; 2-aminoethoxydiphenylborane inhibits the reaction [CD28 protein results in increased abundance of Calcium]; 5-diisopropoxyphosphoryl-5-methyl-1-pyrroline-N-oxide inhibits the reaction [CD28 protein results in increased abundance of Calcium]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [CD28 protein results in increased abundance of Calcium] |
CTD |
PMID:14607919 |
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NCBI chr 2:203,706,482...203,738,912
Ensembl chr 2:203,706,475...203,738,912
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G |
CD38 |
CD38 molecule |
multiple interactions |
ISO |
CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]; CD38 protein inhibits the reaction [CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]] |
CTD |
PMID:20200208 |
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NCBI chr 4:15,778,328...15,853,232
Ensembl chr 4:15,778,275...15,853,232
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G |
CDC42 |
cell division cycle 42 |
multiple interactions |
ISO |
Calcium promotes the reaction [PAFAH1B1 protein binds to IQGAP1 protein binds to CDC42 protein] |
CTD |
PMID:16369480 |
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NCBI chr 1:22,052,709...22,101,360
Ensembl chr 1:22,052,627...22,101,360
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G |
CDC42BPB |
CDC42 binding protein kinase beta |
affects expression |
ISO |
Calcium affects the expression of CDC42BPB mRNA |
CTD |
PMID:15913539 |
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NCBI chr14:102,932,380...103,057,549
Ensembl chr14:102,932,380...103,057,549
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G |
CDK5R1 |
cyclin dependent kinase 5 regulatory subunit 1 |
increases cleavage multiple interactions |
EXP |
Calcium results in increased cleavage of CDK5R1 protein calpeptin inhibits the reaction [Calcium results in increased cleavage of CDK5R1 protein] |
CTD |
PMID:18242949 |
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NCBI chr17:32,486,993...32,491,253
Ensembl chr17:32,486,993...32,491,253
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G |
CEBPB |
CCAAT enhancer binding protein beta |
affects expression |
ISO |
Calcium affects the expression of CEBPB mRNA |
CTD |
PMID:15913539 |
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NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668
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G |
CERK |
ceramide kinase |
multiple interactions |
EXP |
Calcium affects the reaction [CERK protein results in increased phosphorylation of Ceramides] |
CTD |
PMID:16269826 |
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NCBI chr22:46,684,410...46,738,252
Ensembl chr22:46,684,410...46,738,252
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G |
CFB |
complement factor B |
multiple interactions |
ISO |
CFD protein affects the reaction [[cobra venom factor co-treated with Magnesium co-treated with Calcium] results in increased cleavage of CFB protein] |
CTD |
PMID:11724962 |
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NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,086
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G |
CFD |
complement factor D |
multiple interactions |
ISO |
CFD protein affects the reaction [[cobra venom factor co-treated with Magnesium co-treated with Calcium] results in increased cleavage of CFB protein] |
CTD |
PMID:11724962 |
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NCBI chr19:859,664...863,641
Ensembl chr19:859,453...867,884
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G |
CFL1 |
cofilin 1 |
multiple interactions |
EXP |
[Capsaicin results in decreased phosphorylation of and results in increased activity of CFL1 protein] which results in increased import of Calcium |
CTD |
PMID:17303079 |
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NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026
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G |
CHRM1 |
cholinergic receptor muscarinic 1 |
multiple interactions |
EXP ISO |
[Acetylcholine results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; [Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; [Pilocarpine results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; CHRM1 protein promotes the reaction [Methacholine Compounds results in increased abundance of Calcium] 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; 1-oleoyl-2-acetylglycerol promotes the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; [Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; Atropine inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Flufenamic Acid inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Gadolinium inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Lanthanum inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Pirenzepine inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Thapsigargin inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium] [[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; [[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein |
CTD |
PMID:11527950 PMID:11553362 PMID:12456425 PMID:18316702 |
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NCBI chr11:62,908,679...62,921,878
Ensembl chr11:62,908,679...62,921,807
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G |
CHRNA4 |
cholinergic receptor nicotinic alpha 4 subunit |
multiple interactions |
ISO |
[CHRNA4 protein co-treated with CHRNB2 protein mutant form] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein co-treated with CHRNB2 protein] affects the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein mutant form co-treated with CHRNB2 protein] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine] |
CTD |
PMID:12754307 |
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NCBI chr20:63,343,223...63,361,349
Ensembl chr20:63,343,223...63,378,401
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G |
CHRNA7 |
cholinergic receptor nicotinic alpha 7 subunit |
multiple interactions |
EXP ISO |
[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium; [[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] which results in increased uptake of Calcium] inhibits the reaction [CHRNA7 protein results in decreased susceptibility to Okadaic Acid]; [Acetylcholine results in increased activity of CHRNA7 protein] which results in increased uptake of Calcium; [Bungarotoxins binds to and results in increased activity of CHRNA7 protein] which results in increased transport of Calcium; [methyllycaconitine binds to and results in increased activity of CHRNA7 protein] which results in increased transport of Calcium; [Nicotine results in increased activity of CHRNA7 protein] which results in increased transport of Calcium; [PNU-282987 binds to and results in increased activity of CHRNA7 protein] which results in increased uptake of Calcium; Bungarotoxins inhibits the reaction [[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium]; Mecamylamine inhibits the reaction [[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium]; methyllycaconitine inhibits the reaction [[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium]; methyllycaconitine promotes the reaction [[Nicotine results in increased activity of CHRNA7 protein] which results in increased transport of Calcium] |
CTD |
PMID:17709503 PMID:21051662 PMID:21715663 |
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NCBI chr15:32,030,483...32,173,018
Ensembl chr15:31,923,438...32,173,018
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G |
CHRNB2 |
cholinergic receptor nicotinic beta 2 subunit |
multiple interactions |
EXP ISO |
[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium; alpha-conotoxin MII inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium]; Calcium affects the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased susceptibility to Okadaic Acid]; Dihydro-beta-Erythroidine inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium]; Mecamylamine inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium] [CHRNA4 protein co-treated with CHRNB2 protein mutant form] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein co-treated with CHRNB2 protein] affects the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein mutant form co-treated with CHRNB2 protein] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine] |
CTD |
PMID:12754307 PMID:21715663 |
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NCBI chr 1:154,567,778...154,580,013
Ensembl chr 1:154,567,778...154,580,013
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G |
CITED2 |
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 |
affects expression |
ISO |
Calcium affects the expression of CITED2 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 6:139,371,807...139,374,648
Ensembl chr 6:139,371,807...139,374,648
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G |
CLN8 |
CLN8 transmembrane ER and ERGIC protein |
multiple interactions |
ISO |
CLN8 protein affects the reaction [[Ionomycin co-treated with Calcium] results in increased transport of D-Aspartic Acid]; CLN8 protein affects the reaction [[Potassium Chloride co-treated with Calcium] results in increased transport of D-Aspartic Acid] |
CTD |
PMID:22302580 |
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NCBI chr 8:1,753,059...1,786,570
Ensembl chr 8:1,755,778...1,801,711
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G |
CNNM4 |
cyclin and CBS domain divalent metal cation transport mediator 4 |
affects expression |
ISO |
Calcium affects the expression of CNNM4 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 2:96,760,902...96,811,874
Ensembl chr 2:96,760,902...96,811,874
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G |
CNR1 |
cannabinoid receptor 1 |
multiple interactions |
ISO |
[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein] affects the reaction [Potassium Chloride results in increased transport of Calcium]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] affects the reaction [Potassium Chloride results in increased transport of Calcium]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium results in increased transport of Calcium]; Calcium affects the reaction [Potassium Chloride results in decreased expression of CNR1 mRNA]; Calcium affects the reaction [Potassium Chloride results in decreased expression of CNR1 protein]; CNR1 protein affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; CNR1 protein affects the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Pertussis Toxin inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]] |
CTD |
PMID:12421626 PMID:14973253 PMID:16412482 |
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NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347
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G |
CNR2 |
cannabinoid receptor 2 |
multiple interactions |
EXP |
CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]; Pertussis Toxin inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]]; SR 144528 inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]] |
CTD |
PMID:10617657 |
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NCBI chr 1:23,870,515...23,913,362
Ensembl chr 1:23,870,515...23,913,362
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G |
COL18A1 |
collagen type XVIII alpha 1 chain |
affects abundance |
ISO |
COL18A1 protein affects the abundance of Calcium |
CTD |
PMID:15296943 |
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NCBI chr21:45,405,165...45,513,720
Ensembl chr21:45,405,165...45,513,720
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G |
COL1A2 |
collagen type I alpha 2 chain |
affects abundance |
ISO |
COL1A2 protein affects the abundance of Calcium |
CTD |
PMID:10913914 |
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NCBI chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227
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G |
CP |
ceruloplasmin |
affects binding multiple interactions |
EXP ISO |
Calcium binds to CP protein [Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of CP protein] |
CTD |
PMID:17242517 PMID:22534743 |
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NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829
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G |
CREB1 |
cAMP responsive element binding protein 1 |
affects expression multiple interactions |
ISO |
Calcium affects the expression of CREB1 mRNA [Estradiol results in increased import of Calcium] which results in increased activity of CREB1 protein; Calcium promotes the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased phosphorylation of CREB1 protein]; Calcium promotes the reaction [Dopamine results in increased phosphorylation of CREB1 protein] |
CTD |
PMID:14622123 PMID:15802184 PMID:15913539 |
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NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
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G |
CSNK1A1 |
casein kinase 1 alpha 1 |
affects expression |
ISO |
Calcium affects the expression of CSNK1A1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 5:149,492,982...149,551,439
Ensembl chr 5:149,492,982...149,551,471
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G |
CSNK1G3 |
casein kinase 1 gamma 3 |
affects expression |
ISO |
Calcium affects the expression of CSNK1G3 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 5:123,512,177...123,617,049
Ensembl chr 5:123,512,177...123,617,049
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G |
CTNNB1 |
catenin beta 1 |
increases expression multiple interactions |
EXP |
Calcium results in increased expression of CTNNB1 mRNA; Calcium results in increased expression of CTNNB1 protein CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein] |
CTD |
PMID:24658506 |
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NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
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G |
CTSS |
cathepsin S |
multiple interactions |
EXP |
[CTSS protein results in increased cleavage of and results in decreased activity of CXCL10 protein] which results in decreased uptake of Calcium; [CTSS protein results in increased cleavage of and results in decreased activity of CXCL9 protein] which results in decreased uptake of Calcium; [CTSS protein results in increased cleavage of and results in increased activity of CXCL2 protein] which results in increased uptake of Calcium; [CTSS protein results in increased cleavage of and results in increased activity of CXCL5 protein] which results in increased uptake of Calcium |
CTD |
PMID:25833952 |
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NCBI chr 1:150,730,188...150,765,778
Ensembl chr 1:150,730,079...150,765,957
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G |
CXCL1 |
C-X-C motif chemokine ligand 1 |
increases abundance multiple interactions |
ISO |
CXCL1 protein results in increased abundance of Calcium epigallocatechin gallate inhibits the reaction [CXCL1 protein results in increased abundance of Calcium] |
CTD |
PMID:9430702 PMID:15237969 |
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NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
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G |
CXCL10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
EXP |
[CTSS protein results in increased cleavage of and results in decreased activity of CXCL10 protein] which results in decreased uptake of Calcium; [CXCL10 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium |
CTD |
PMID:25833952 |
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NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
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G |
CXCL12 |
C-X-C motif chemokine ligand 12 |
multiple interactions increases uptake |
EXP |
resveratrol inhibits the reaction [CXCL12 protein affects the localization of Calcium] CXCL12 protein results in increased uptake of Calcium |
CTD |
PMID:10984371 PMID:11872090 PMID:16212921 |
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NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493
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G |
CXCL2 |
C-X-C motif chemokine ligand 2 |
multiple interactions |
EXP |
[CTSS protein results in increased cleavage of and results in increased activity of CXCL2 protein] which results in increased uptake of Calcium; [CXCL2 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium |
CTD |
PMID:25833952 |
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NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
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G |
CXCL5 |
C-X-C motif chemokine ligand 5 |
multiple interactions |
EXP |
[CTSS protein results in increased cleavage of and results in increased activity of CXCL5 protein] which results in increased uptake of Calcium; [CXCL5 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium |
CTD |
PMID:25833952 |
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NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677
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G |
CXCL8 |
C-X-C motif chemokine ligand 8 |
multiple interactions increases uptake increases abundance |
EXP |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[PLA2G1B protein results in increased abundance of Calcium] which results in increased expression of CXCL8 protein]; [CXCL8 protein binds to and results in increased activity of CXCR1 protein] which results in increased abundance of and results in increased activity of Calcium; [CXCL8 protein binds to and results in increased activity of CXCR2 protein] which results in increased abundance of and results in increased activity of Calcium; [PLA2G1B protein results in increased abundance of Calcium] which results in increased expression of CXCL8 protein; Calcium promotes the reaction [Neurotensin results in increased expression of CXCL8 mRNA]; CXCL8 protein affects the localization of and affects the abundance of Calcium; resveratrol inhibits the reaction [CXCL8 protein affects the localization of Calcium] CXCL8 protein results in increased uptake of Calcium CXCL8 protein results in increased abundance of Calcium |
CTD |
PMID:10984371 PMID:11298490 PMID:14505796 PMID:15528384 PMID:15748943 PMID:16212921 PMID:17000667 More...
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NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
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G |
CXCL9 |
C-X-C motif chemokine ligand 9 |
multiple interactions increases abundance |
EXP |
[[CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium] which results in increased expression of EGR1 mRNA; [CTSS protein results in increased cleavage of and results in decreased activity of CXCL9 protein] which results in decreased uptake of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium CXCL9 protein results in increased abundance of Calcium |
CTD |
PMID:12517959 PMID:25833952 |
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NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509
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G |
CXCR1 |
C-X-C motif chemokine receptor 1 |
multiple interactions affects abundance |
EXP |
[CXCL8 protein binds to and results in increased activity of CXCR1 protein] which results in increased abundance of and results in increased activity of Calcium CXCR1 protein affects the abundance of Calcium |
CTD |
PMID:11298490 PMID:12055238 |
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NCBI chr 2:218,162,841...218,166,962
Ensembl chr 2:218,162,841...218,166,962
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G |
CXCR2 |
C-X-C motif chemokine receptor 2 |
affects transport multiple interactions |
EXP ISO |
CXCR2 protein affects the transport of Calcium [CXCL2 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium; [CXCL5 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium; [CXCL8 protein binds to and results in increased activity of CXCR2 protein] which results in increased abundance of and results in increased activity of Calcium Excitatory Amino Acid Agonists inhibits the reaction [CXCR2 protein affects the localization of Calcium] |
CTD |
PMID:11298490 PMID:15618463 PMID:15914698 PMID:25833952 |
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NCBI chr 2:218,125,294...218,137,251
Ensembl chr 2:218,125,289...218,137,251
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G |
CXCR3 |
C-X-C motif chemokine receptor 3 |
affects abundance multiple interactions |
EXP |
CXCR3 protein affects the abundance of Calcium [[CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium] which results in increased expression of EGR1 mRNA; [CXCL10 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium |
CTD |
PMID:12055238 PMID:12517959 PMID:25833952 |
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NCBI chr X:71,615,919...71,618,511
Ensembl chr X:71,615,916...71,618,511
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G |
CXCR4 |
C-X-C motif chemokine receptor 4 |
affects abundance |
EXP |
CXCR4 protein affects the abundance of Calcium |
CTD |
PMID:12055238 |
|
NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177
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G |
CXCR5 |
C-X-C motif chemokine receptor 5 |
affects abundance |
EXP |
CXCR5 protein affects the abundance of Calcium |
CTD |
PMID:12055238 |
|
NCBI chr11:118,883,892...118,897,787
Ensembl chr11:118,883,892...118,897,787
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G |
CYCS |
cytochrome c, somatic |
multiple interactions increases secretion decreases secretion |
ISO |
[Calcium co-treated with Phosphates] affects the localization of CYCS protein; caffeic acid phenethyl ester inhibits the reaction [Calcium results in increased secretion of CYCS protein]; Cyclosporine inhibits the reaction [[Calcium co-treated with Phosphates] affects the localization of CYCS protein]; Nicotine inhibits the reaction [[Calcium co-treated with Phosphates] affects the localization of CYCS protein]; xestospongin C inhibits the reaction [Calcium results in decreased secretion of CYCS protein] |
CTD |
PMID:15345483 PMID:15469948 PMID:15985439 |
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NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
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G |
CYP1A1 |
cytochrome P450 family 1 subfamily A member 1 |
multiple interactions |
EXP ISO |
2-aminoethoxydiphenyl borate inhibits the reaction [[oltipraz results in increased abundance of Calcium] which results in increased expression of CYP1A1 mRNA]; [2,3,7,8-tetrachlorodibenzofuran co-treated with Calcium] results in increased expression of CYP1A1 mRNA; [oltipraz results in increased abundance of Calcium] which results in increased expression of CYP1A1 mRNA; Calcium promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; Calcium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein] |
CTD |
PMID:1979076 PMID:11959854 PMID:16237193 PMID:23298284 |
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NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
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G |
CYP1B1 |
cytochrome P450 family 1 subfamily B member 1 |
multiple interactions |
EXP ISO |
Calcium promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; Calcium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] |
CTD |
PMID:16237193 PMID:19782052 |
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NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
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G |
CYP24A1 |
cytochrome P450 family 24 subfamily A member 1 |
affects expression multiple interactions |
ISO |
Calcium affects the expression of CYP24A1 mRNA [Calcium co-treated with Calcitriol] affects the expression of CYP24A1 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr20:54,143,538...54,173,986
Ensembl chr20:54,153,446...54,173,986
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G |
CYP27B1 |
cytochrome P450 family 27 subfamily B member 1 |
affects expression |
ISO |
Calcium affects the expression of CYP27B1 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr12:57,762,334...57,767,078
Ensembl chr12:57,762,334...57,768,986
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G |
CYP2E1 |
cytochrome P450 family 2 subfamily E member 1 |
affects expression decreases uptake |
ISO EXP |
Calcium affects the expression of CYP2E1 mRNA CYP2E1 protein results in decreased uptake of Calcium |
CTD |
PMID:15913539 PMID:19028543 |
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NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
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G |
CYSLTR1 |
cysteinyl leukotriene receptor 1 |
multiple interactions |
EXP ISO |
[CP 199330 binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; [CP 199331 binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; [CP 265298 binds to and results in decreased activity of CYSLTR1 protein] which results in decreased abundance of Calcium; [CP 288886 binds to and results in decreased activity of CYSLTR1 protein] which results in decreased abundance of Calcium; [Leukotriene C4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [Leukotriene D4 results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [Leukotriene E4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [pranlukast binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; [Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [zafirlukast binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; BAY u9773 inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; CYSLTR1 protein promotes the reaction [Leukotriene D4 results in increased abundance of Calcium]; montelukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; montelukast inhibits the reaction [[Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; pobilukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; pranlukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; verlukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; zafirlukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; zafirlukast inhibits the reaction [[Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; zafirlukast inhibits the reaction [CYSLTR1 protein promotes the reaction [Leukotriene D4 results in increased abundance of Calcium]] |
CTD |
PMID:8014876 PMID:9934474 PMID:10391245 PMID:10462554 PMID:10509933 PMID:11093801 PMID:11705452 PMID:12853847 PMID:15792791 PMID:15990778 PMID:18704935 PMID:20083671 More...
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NCBI chr X:78,271,468...78,327,611
Ensembl chr X:78,271,468...78,327,691
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G |
CYSLTR2 |
cysteinyl leukotriene receptor 2 |
multiple interactions |
EXP |
[Leukotriene C4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene C4 results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene D4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene D4 results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene E4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene E4 results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; BAY u9773 inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium] |
CTD |
PMID:10851239 PMID:11093801 |
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NCBI chr13:48,653,929...48,711,226
Ensembl chr13:48,653,711...48,711,226
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G |
DDR1 |
discoidin domain receptor tyrosine kinase 1 |
affects expression |
ISO |
Calcium affects the expression of DDR1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 6:30,880,970...30,900,156
Ensembl chr 6:30,876,421...30,900,156
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G |
DMD |
dystrophin |
increases abundance multiple interactions |
ISO |
DMD gene mutant form results in increased abundance of Calcium Nifedipine inhibits the reaction [DMD gene mutant form results in increased abundance of Calcium] |
CTD |
PMID:24349043 |
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NCBI chr X:31,119,222...33,339,388
Ensembl chr X:31,097,677...33,339,609
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G |
DNAJB11 |
DnaJ heat shock protein family (Hsp40) member B11 |
multiple interactions decreases transport |
EXP |
[DNAJB11 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [DNAJB11 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin; DNAJB11 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium] |
CTD |
PMID:26085089 |
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NCBI chr 3:186,570,720...186,585,793
Ensembl chr 3:186,567,403...186,585,800
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G |
DNAJC3 |
DnaJ heat shock protein family (Hsp40) member C3 |
multiple interactions decreases transport |
EXP |
[DNAJC3 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [DNAJC3 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin; DNAJC3 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium] |
CTD |
PMID:26085089 |
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NCBI chr13:95,677,139...95,794,988
Ensembl chr13:95,677,139...95,794,988
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G |
DRD1 |
dopamine receptor D1 |
multiple interactions |
ISO |
[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased activity of DRD1 protein] which results in increased abundance of Calcium |
CTD |
PMID:14622123 |
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NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
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G |
DRD2 |
dopamine receptor D2 |
multiple interactions |
EXP ISO |
[Norepinephrine binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium; [Quinpirole binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium; Sulpiride inhibits the reaction [[Norepinephrine binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium]; Sulpiride inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium] [DRD2 protein affects the abundance of Calcium] which results in decreased transport of Barium |
CTD |
PMID:8032591 PMID:11124974 |
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NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
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G |
DRD3 |
dopamine receptor D3 |
increases phosphorylation |
ISO |
Calcium results in increased phosphorylation of DRD3 protein |
CTD |
PMID:19217379 |
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NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
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G |
DUSP1 |
dual specificity phosphatase 1 |
multiple interactions |
ISO |
Calcium affects the reaction [Potassium Chloride results in increased expression of DUSP1 mRNA] |
CTD |
PMID:11577072 |
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NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195
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G |
EDN1 |
endothelin 1 |
increases abundance increases uptake multiple interactions affects transport affects localization |
ISO EXP |
EDN1 protein results in increased abundance of Calcium EDN1 protein results in increased uptake of Calcium EDN1 protein affects the localization of and affects the abundance of Calcium Carvedilol inhibits the reaction [EDN1 protein results in increased import of and results in increased abundance of Calcium]; EDN1 protein affects the abundance of and affects the localization of Calcium; EDN1 protein results in increased import of and results in increased abundance of Calcium; Glucose affects the reaction [EDN1 protein affects the abundance of and affects the localization of Calcium]; Heparin inhibits the reaction [EDN1 protein results in increased abundance of Calcium] EDN1 protein affects the transport of Calcium EDN1 protein results in increased transport of and results in increased abundance of Calcium; Propofol inhibits the reaction [EDN1 protein affects the transport of Calcium] EDN1 protein affects the localization of Calcium |
CTD |
PMID:1443220 PMID:9138053 PMID:11425647 PMID:12628492 PMID:12821678 PMID:14711191 PMID:27226631 More...
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NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194
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G |
EDN2 |
endothelin 2 |
increases uptake multiple interactions |
ISO |
EDN2 protein results in increased uptake of Calcium EDN2 protein affects the localization of and affects the abundance of Calcium |
CTD |
PMID:11425647 |
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NCBI chr 1:41,478,775...41,484,683
Ensembl chr 1:41,478,775...41,484,683
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G |
EDN3 |
endothelin 3 |
multiple interactions increases uptake |
ISO |
EDN3 protein affects the localization of and affects the abundance of Calcium BQ 788 inhibits the reaction [EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium]]; EDN3 protein inhibits the reaction [APP protein results in increased uptake of Calcium]; EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium] EDN3 protein results in increased uptake of Calcium |
CTD |
PMID:11425647 PMID:12383957 PMID:15695168 |
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NCBI chr20:59,300,611...59,325,992
Ensembl chr20:59,300,443...59,325,992
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G |
EDNRA |
endothelin receptor type A |
affects activity |
ISO |
Calcium affects the activity of EDNRA protein |
CTD |
PMID:12628492 |
|
NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954
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G |
EEF2 |
eukaryotic translation elongation factor 2 |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of EEF2 mRNA |
CTD |
PMID:15913539 |
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NCBI chr19:3,976,056...3,985,463
Ensembl chr19:3,976,056...3,985,463
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G |
EGF |
epidermal growth factor |
increases abundance multiple interactions affects expression increases transport |
EXP ISO |
EGF protein results in increased abundance of Calcium [Calcium co-treated with Calcitriol] affects the expression of EGF mRNA Calcium affects the expression of EGF mRNA EGF protein results in increased transport of Calcium [IGF2 protein co-treated with EGF protein] results in increased import of Calcium RTKI cpd inhibits the reaction [EGF protein results in increased abundance of Calcium] |
CTD |
PMID:2442157 PMID:11527950 PMID:15913539 PMID:24990931 |
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NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
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G |
EGFR |
epidermal growth factor receptor |
multiple interactions |
ISO |
Calcium affects the phosphorylation of and affects the expression of EGFR protein |
CTD |
PMID:8393775 |
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NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
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G |
EGR1 |
early growth response 1 |
multiple interactions |
EXP |
[[CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium] which results in increased expression of EGR1 mRNA; [Ionomycin results in increased abundance of Calcium] which results in increased expression of EGR1 protein |
CTD |
PMID:12517959 |
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NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
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G |
EIF2AK3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions |
EXP |
Calcium promotes the reaction [Diclofenac results in increased phosphorylation of EIF2AK3 protein] |
CTD |
PMID:26609140 |
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NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518
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G |
EIF4A2 |
eukaryotic translation initiation factor 4A2 |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of EIF4A2 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 3:186,783,577...186,789,897
Ensembl chr 3:186,783,205...186,789,897
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G |
EIF4EBP1 |
eukaryotic translation initiation factor 4E binding protein 1 |
multiple interactions |
ISO |
Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of EIF4EBP1 protein] |
CTD |
PMID:12935885 |
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NCBI chr 8:38,030,534...38,060,365
Ensembl chr 8:38,030,534...38,060,365
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G |
EPHX2 |
epoxide hydrolase 2 |
affects expression |
ISO |
Calcium affects the expression of EPHX2 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564
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G |
F2 |
coagulation factor II, thrombin |
increases abundance increases localization multiple interactions increases uptake |
EXP |
F2 protein results in increased abundance of Calcium F2 protein results in increased localization of Calcium 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [F2 protein results in increased localization of Calcium]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [F2 protein results in increased localization of Calcium]; Apigenin inhibits the reaction [F2 protein results in increased localization of Calcium]; arsenite inhibits the reaction [F2 protein results in increased abundance of Calcium]; Genistein inhibits the reaction [F2 protein results in increased localization of Calcium]; Nickel inhibits the reaction [F2 protein results in increased uptake of Calcium]; Quercetin inhibits the reaction [F2 protein results in increased localization of Calcium] |
CTD |
PMID:2125206 PMID:19814731 PMID:22244921 |
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NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
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G |
F2R |
coagulation factor II thrombin receptor |
multiple interactions |
ISO |
[Peptides results in increased activity of F2R protein] which results in increased abundance of Calcium |
CTD |
PMID:15086339 |
|
NCBI chr 5:76,716,126...76,735,770
Ensembl chr 5:76,716,126...76,735,770
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|
G |
F2RL1 |
F2R like trypsin receptor 1 |
multiple interactions |
EXP |
F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]; PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]] |
CTD |
PMID:16793902 |
|
NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315
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|
G |
F2RL3 |
F2R like thrombin or trypsin receptor 3 |
multiple interactions |
EXP ISO |
[alanyl-tyrosyl-prolyl-glycyl-lysyl-phenylalanine binds to and results in increased activity of F2RL3 protein] which results in increased uptake of Calcium F2RL3 protein affects the localization of and affects the transport of Calcium |
CTD |
PMID:16702038 PMID:17707436 |
|
NCBI chr19:16,888,999...16,892,606
Ensembl chr19:16,888,999...16,892,606
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G |
F8 |
coagulation factor VIII |
multiple interactions |
EXP |
[Copper co-treated with Calcium] results in increased activity of [F8 protein alternative form binds to F8 protein alternative form]; Calcium results in increased activity of [F8 protein alternative form binds to F8 protein alternative form] |
CTD |
PMID:11513607 |
|
NCBI chr X:154,835,792...155,022,723
Ensembl chr X:154,835,788...155,026,940
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G |
FASLG |
Fas ligand |
multiple interactions affects localization |
ISO |
bafilomycin A1 inhibits the reaction [FASL protein affects the localization of Calcium]; CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]; CD38 protein inhibits the reaction [CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]]; Ryanodine inhibits the reaction [FASL protein affects the localization of Calcium] |
CTD |
PMID:20200208 |
|
NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
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G |
FGF1 |
fibroblast growth factor 1 |
increases expression |
ISO |
Calcium results in increased expression of FGF1 protein |
CTD |
PMID:15264218 |
|
NCBI chr 5:142,592,178...142,698,070
Ensembl chr 5:142,592,178...142,698,070
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G |
FGF23 |
fibroblast growth factor 23 |
affects expression |
EXP |
Calcium affects the expression of FGF23 mRNA; Calcium affects the expression of FGF23 protein |
CTD |
PMID:15086938 PMID:16381997 |
|
NCBI chr12:4,368,227...4,379,712
Ensembl chr12:4,368,227...4,379,712
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|
G |
FGF9 |
fibroblast growth factor 9 |
affects expression |
ISO |
Calcium affects the expression of FGF9 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr13:21,671,073...21,704,498
Ensembl chr13:21,671,073...21,704,498
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|
G |
FGFR1 |
fibroblast growth factor receptor 1 |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of FGFR1 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
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|
G |
FIS1 |
fission, mitochondrial 1 |
affects expression |
ISO |
Calcium affects the expression of FIS1 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316
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|
G |
FKBP1A |
FKBP prolyl isomerase 1A |
multiple interactions |
EXP |
FKBP1A protein inhibits the reaction [Calcium results in increased activity of RYR2 protein] |
CTD |
PMID:17872463 |
|
NCBI chr20:1,368,978...1,393,054
Ensembl chr20:1,368,977...1,393,164
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G |
FKBP1B |
FKBP prolyl isomerase 1B |
multiple interactions |
ISO |
FKBP1B gene mutant form inhibits the reaction [Acetylcholine affects the localization of and affects the abundance of Calcium]; Ryanodine inhibits the reaction [FKBP1B gene mutant form inhibits the reaction [Acetylcholine affects the localization of and affects the abundance of Calcium]] |
CTD |
PMID:17261647 |
|
NCBI chr 2:24,033,206...24,063,681
Ensembl chr 2:24,049,701...24,063,681
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G |
FURIN |
furin, paired basic amino acid cleaving enzyme |
affects expression |
ISO |
Calcium affects the expression of FURIN mRNA |
CTD |
PMID:15913539 |
|
NCBI chr15:90,868,588...90,883,457
Ensembl chr15:90,868,588...90,883,564
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G |
FXYD2 |
FXYD domain containing ion transport regulator 2 |
multiple interactions decreases activity |
EXP |
Calcium inhibits the reaction [FXYD2 protein results in increased transport of Deoxyglucose]; Calcium inhibits the reaction [FXYD2 protein results in increased transport of Inulin] Calcium results in decreased activity of FXYD2 protein |
CTD |
PMID:11533133 |
|
NCBI chr11:117,820,057...117,828,089
Ensembl chr11:117,800,844...117,828,698
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G |
G6PC1 |
glucose-6-phosphatase catalytic subunit 1 |
affects expression |
ISO |
Calcium affects the expression of G6PC1 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438
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G |
GABBR1 |
gamma-aminobutyric acid type B receptor subunit 1 |
multiple interactions affects expression |
EXP ISO |
Calcium promotes the reaction [3-aminopropylphosphinic acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]; Calcium promotes the reaction [CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]]; Calcium promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]] Calcium affects the expression of GABBR1 mRNA |
CTD |
PMID:15627515 PMID:15913539 |
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NCBI chr 6:29,602,238...29,633,183
Ensembl chr 6:29,555,629...29,633,976
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G |
GABBR2 |
gamma-aminobutyric acid type B receptor subunit 2 |
multiple interactions |
EXP |
Calcium promotes the reaction [3-aminopropylphosphinic acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]; Calcium promotes the reaction [CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]]; Calcium promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]] |
CTD |
PMID:15627515 |
|
NCBI chr 9:98,288,109...98,708,935
Ensembl chr 9:98,288,109...98,708,935
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G |
GAST |
gastrin |
multiple interactions |
EXP |
Calcium promotes the reaction [Colforsin results in increased secretion of GAST protein]; Calcium promotes the reaction [Terbutaline results in increased secretion of GAST protein] |
CTD |
PMID:9277405 |
|
NCBI chr17:41,712,331...41,715,969
Ensembl chr17:41,712,331...41,715,969
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G |
GATA1 |
GATA binding protein 1 |
affects expression |
ISO |
Calcium affects the expression of GATA1 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr X:48,786,590...48,794,311
Ensembl chr X:48,786,540...48,794,311
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G |
GC |
GC vitamin D binding protein |
affects expression |
ISO |
Calcium affects the expression of GC mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 4:71,741,693...71,805,520
Ensembl chr 4:71,741,696...71,804,041
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G |
GCG |
glucagon |
multiple interactions |
ISO |
Calcium affects the reaction [Pyruvic Acid results in increased secretion of GCG protein] |
CTD |
PMID:15919803 |
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NCBI chr 2:162,142,882...162,152,247
Ensembl chr 2:162,142,882...162,152,404
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G |
GCLC |
glutamate-cysteine ligase catalytic subunit |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of GCLC mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
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G |
GFAP |
glial fibrillary acidic protein |
multiple interactions |
ISO |
Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]; Calcium deficiency inhibits the reaction [Ethanol results in increased expression of GFAP protein] |
CTD |
PMID:17888892 PMID:21879721 |
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NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937
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G |
GHR |
growth hormone receptor |
affects expression multiple interactions |
ISO |
Calcium affects the expression of GHR mRNA [Calcium co-treated with Calcitriol] affects the expression of GHR mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 5:42,423,439...42,721,878
Ensembl chr 5:42,423,439...42,721,878
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G |
GIPC3 |
GIPC PDZ domain containing family member 3 |
affects uptake |
ISO |
GIPC3 protein affects the uptake of Calcium |
CTD |
PMID:27462107 |
|
NCBI chr19:3,585,478...3,593,541
Ensembl chr19:3,585,478...3,593,541
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G |
GLRX3 |
glutaredoxin 3 |
affects response to substance |
ISO |
GLRX3 protein affects the susceptibility to Calcium |
CTD |
PMID:16809552 |
|
NCBI chr10:130,136,391...130,180,377
Ensembl chr10:130,136,391...130,184,521
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G |
GNAI2 |
G protein subunit alpha i2 |
affects expression |
ISO |
Calcium affects the expression of GNAI2 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 3:50,227,068...50,263,358
Ensembl chr 3:50,226,292...50,259,362
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G |
GNAS |
GNAS complex locus |
multiple interactions |
ISO |
[[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium; [[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium |
CTD |
PMID:23022524 |
|
NCBI chr20:58,839,748...58,911,192
Ensembl chr20:58,839,718...58,911,192
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G |
GPBAR1 |
G protein-coupled bile acid receptor 1 |
multiple interactions |
EXP ISO |
[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased abundance of Calcium [[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium; [[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium |
CTD |
PMID:23022524 |
|
NCBI chr 2:218,259,496...218,263,861
Ensembl chr 2:218,259,496...218,263,861
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G |
GRIA1 |
glutamate ionotropic receptor AMPA type subunit 1 |
multiple interactions |
ISO |
Calcium deficiency inhibits the reaction [Excitatory Amino Acid Agonists results in decreased phosphorylation of GRIA1 protein] |
CTD |
PMID:28404816 |
|
NCBI chr 5:153,489,615...153,813,869
Ensembl chr 5:153,489,615...153,813,869
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G |
GRIA2 |
glutamate ionotropic receptor AMPA type subunit 2 |
multiple interactions |
ISO |
Calcium promotes the reaction [PICK1 protein binds to GRIA2 protein] |
CTD |
PMID:28404816 |
|
NCBI chr 4:157,220,120...157,366,075
Ensembl chr 4:157,204,182...157,387,146
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G |
GRM1 |
glutamate metabotropic receptor 1 |
multiple interactions |
ISO |
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]; [3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium; Flufenamic Acid inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]; GRM1 protein promotes the reaction [Propionates results in increased transport of Calcium]; Ruthenium Red inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium] |
CTD |
PMID:14622174 PMID:24582715 |
|
NCBI chr 6:146,027,707...146,437,601
Ensembl chr 6:146,027,646...146,437,601
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G |
GSR |
glutathione-disulfide reductase |
multiple interactions |
ISO |
[Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in decreased activity of GSR protein]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in decreased activity of GSR protein]; [Carmustine results in decreased activity of GSR protein] which results in increased uptake of Calcium; Calcium affects the reaction [sodium arsenite results in decreased activity of GSR protein] |
CTD |
PMID:15321730 PMID:24184500 |
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NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
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G |
HCAR3 |
hydroxycarboxylic acid receptor 3 |
increases abundance multiple interactions |
EXP |
HCAR3 protein results in increased abundance of Calcium Pertussis Toxin affects the reaction [HCAR3 protein results in increased abundance of Calcium] |
CTD |
PMID:19237584 |
|
NCBI chr12:122,714,756...122,716,811
Ensembl chr12:122,714,756...122,716,811
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G |
HECTD4 |
HECT domain E3 ubiquitin protein ligase 4 |
multiple interactions |
EXP |
Calcium affects the reaction [HECTD4 gene SNP affects the abundance of Lead] |
CTD |
PMID:28212632 |
|
NCBI chr12:112,160,195...112,382,431
Ensembl chr12:112,160,188...112,382,439
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G |
HES1 |
hes family bHLH transcription factor 1 |
affects expression |
ISO |
Calcium affects the expression of HES1 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732
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G |
HGF |
hepatocyte growth factor |
increases abundance |
ISO |
HGF protein results in increased abundance of Calcium |
CTD |
PMID:10963052 |
|
NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438
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G |
HMGCS2 |
3-hydroxy-3-methylglutaryl-CoA synthase 2 |
affects expression |
ISO |
Calcium affects the expression of HMGCS2 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 1:119,747,996...119,768,932
Ensembl chr 1:119,748,002...119,768,905
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G |
HMOX1 |
heme oxygenase 1 |
multiple interactions |
EXP |
Calcium affects the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA] |
CTD |
PMID:21443188 |
|
NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
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G |
HNF4A |
hepatocyte nuclear factor 4 alpha |
affects expression |
ISO |
Calcium affects the expression of HNF4A mRNA |
CTD |
PMID:15913539 |
|
NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,699...44,432,845
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G |
HNRNPD |
heterogeneous nuclear ribonucleoprotein D |
multiple interactions |
ISO |
Calcium deficiency promotes the reaction [HNRNPD protein binds to PTH 3' UTR] |
CTD |
PMID:18583400 |
|
NCBI chr 4:82,352,498...82,373,991
Ensembl chr 4:82,352,498...82,374,503
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G |
HNRNPU |
heterogeneous nuclear ribonucleoprotein U |
affects expression |
ISO |
Calcium affects the expression of SP120 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 1:244,850,297...244,864,543
Ensembl chr 1:244,840,638...244,864,560
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G |
HOMER1 |
homer scaffold protein 1 |
multiple interactions |
ISO |
HOMER1 protein alternative form inhibits the reaction [Caffeine promotes the reaction [RYR2 protein results in increased secretion of Calcium]]; HOMER1 protein alternative form inhibits the reaction [Cyclic ADP-Ribose promotes the reaction [RYR2 protein results in increased secretion of Calcium]] |
CTD |
PMID:12887973 |
|
NCBI chr 5:79,372,636...79,514,134
Ensembl chr 5:79,372,636...79,514,134
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G |
HPCA |
hippocalcin |
decreases response to substance |
ISO |
HPCA protein results in decreased susceptibility to Calcium |
CTD |
PMID:12445469 |
|
NCBI chr 1:32,885,996...32,894,646
Ensembl chr 1:32,885,994...32,898,441
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G |
HRH1 |
histamine receptor H1 |
multiple interactions increases abundance |
EXP |
[6-((2-(4-imidazolyl)ethyl)amino)heptanoic acid 4-toluidide binds to and results in increased activity of HRH1 protein] which results in increased abundance of Calcium; [Histamine results in increased activity of HRH1 protein] which results in increased abundance of Calcium; [HRH1 protein binds to Histamine] which results in increased import of Calcium; [HRH1 protein binds to Lidocaine] which results in increased import of Calcium; [HRH1 protein binds to Procaine] which results in increased import of Calcium; [HRH1 protein binds to Tetracaine] which results in increased import of Calcium; fexofenadine inhibits the reaction [[Histamine binds to and results in increased activity of HRH1 protein] which results in increased abundance of Calcium]; HRH1 protein promotes the reaction [Histamine results in increased export of Calcium]; Triprolidine inhibits the reaction [[Histamine results in increased activity of HRH1 protein] which results in increased abundance of Calcium]; Triprolidine inhibits the reaction [HRH1 protein promotes the reaction [Histamine results in increased export of Calcium]] HRH1 protein results in increased abundance of Calcium |
CTD |
PMID:2419744 PMID:11238657 PMID:11527950 PMID:19443731 PMID:32061592 |
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NCBI chr 3:11,137,238...11,263,557
Ensembl chr 3:11,137,093...11,263,557
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G |
HRH3 |
histamine receptor H3 |
multiple interactions |
ISO |
[4-(1H-imidazol-4-ylmethyl)piperidine binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; [Histamine binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; [imetit binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; [Methylhistamines binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; clobenpropit inhibits the reaction [[Methylhistamines binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium] |
CTD |
PMID:12706455 |
|
NCBI chr20:62,214,960...62,220,278
Ensembl chr20:62,214,960...62,220,278
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G |
HRH4 |
histamine receptor H4 |
multiple interactions |
EXP |
1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine inhibits the reaction [[4-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium]; 1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine inhibits the reaction [[clobenpropit binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium]; [4-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [alpha-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [clobenpropit binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [Histamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [imetit binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [N-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium |
CTD |
PMID:11181941 PMID:17507084 |
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NCBI chr18:24,460,637...24,479,974
Ensembl chr18:24,460,637...24,479,961
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G |
HSD17B12 |
hydroxysteroid 17-beta dehydrogenase 12 |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of HSD17B12 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr11:43,556,721...43,856,615
Ensembl chr11:43,680,680...43,856,617
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G |
HSP90AA1 |
heat shock protein 90 alpha family class A member 1 |
multiple interactions |
ISO |
Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]] |
CTD |
PMID:23184943 |
|
NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699
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|
G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions decreases transport |
EXP |
[DNAJB11 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [DNAJC3 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [HSPA5 protein binds to SEC61A1 protein] which results in decreased transport of Calcium; [HSPA5 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin |
CTD |
PMID:26085089 |
|
NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
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|
G |
HSPA9 |
heat shock protein family A (Hsp70) member 9 |
increases abundance |
ISO |
HSPA9 protein results in increased abundance of Calcium |
CTD |
PMID:34308505 |
|
NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,675
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|
G |
HTR1A |
5-hydroxytryptamine receptor 1A |
increases activity |
EXP |
Calcium results in increased activity of HTR1A protein |
CTD |
PMID:11356925 |
|
NCBI chr 5:63,957,874...63,962,445
Ensembl chr 5:63,957,874...63,962,507
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G |
HTR2A |
5-hydroxytryptamine receptor 2A |
multiple interactions |
ISO |
HTR2A protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium] |
CTD |
PMID:16901936 |
|
NCBI chr13:46,831,546...46,898,082
Ensembl chr13:46,831,546...46,897,076
|
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G |
HTR2B |
5-hydroxytryptamine receptor 2B |
multiple interactions |
ISO |
Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK1 protein]; Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:18758753 |
|
NCBI chr 2:231,108,230...231,125,042
Ensembl chr 2:231,108,230...231,125,042
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|
G |
HTR7 |
5-hydroxytryptamine receptor 7 |
multiple interactions |
ISO |
HTR7 protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium] |
CTD |
PMID:16901936 |
|
NCBI chr10:90,740,823...90,858,039
Ensembl chr10:90,740,823...90,858,039
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G |
IFNG |
interferon gamma |
multiple interactions |
ISO EXP |
KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]] [IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]; [TNF protein co-treated with IFNG protein] promotes the reaction [Diclofenac affects the abundance of Calcium]; Calcium promotes the reaction [[Diclofenac co-treated with IFNG protein] results in increased phosphorylation of STAT1 protein] |
CTD |
PMID:23747339 PMID:26609140 |
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NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
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G |
IFT88 |
intraflagellar transport 88 |
multiple interactions increases uptake |
ISO |
Gadolinium inhibits the reaction [IFT88 protein mutant form results in increased uptake of Calcium]; IFT88 protein affects the reaction [PKD2 protein results in increased uptake of Calcium] |
CTD |
PMID:16396941 |
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NCBI chr13:20,567,157...20,691,444
Ensembl chr13:20,567,138...20,691,444
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G |
IGF1 |
insulin like growth factor 1 |
affects expression multiple interactions increases import |
ISO |
Calcium affects the expression of IGF1 mRNA Cobalt inhibits the reaction [IGF1 protein results in increased import of Calcium]; tetramethrin inhibits the reaction [IGF1 protein results in increased import of Calcium] |
CTD |
PMID:1550224 PMID:2460452 PMID:2539779 PMID:15913539 |
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NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744
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G |
IGF2 |
insulin like growth factor 2 |
multiple interactions increases import |
ISO |
[IGF2 protein co-treated with EGF protein] results in increased import of Calcium; Cobalt inhibits the reaction [IGF2 protein results in increased import of Calcium]; Lanthanum inhibits the reaction [IGF2 protein results in increased import of Calcium]; Pertussis Toxin inhibits the reaction [IGF2 protein results in increased import of Calcium]; tetramethrin inhibits the reaction [IGF2 protein results in increased import of Calcium] |
CTD |
PMID:2442157 PMID:2460452 PMID:2539779 |
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NCBI chr11:2,129,117...2,149,566
Ensembl chr11:2,129,112...2,158,391
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G |
IGFBP2 |
insulin like growth factor binding protein 2 |
affects expression |
ISO |
Calcium affects the expression of IGFBP2 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 2:216,632,828...216,664,436
Ensembl chr 2:216,632,828...216,664,436
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G |
IGFBP5 |
insulin like growth factor binding protein 5 |
affects expression decreases degradation |
ISO |
Calcium affects the expression of IGFBP5 mRNA Calcium results in decreased degradation of IGFBP5 protein |
CTD |
PMID:8894652 PMID:15913539 |
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NCBI chr 2:216,672,105...216,695,549
Ensembl chr 2:216,672,105...216,695,549
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G |
IL11 |
interleukin 11 |
multiple interactions increases abundance |
ISO |
Flurbiprofen inhibits the reaction [IL11 protein results in increased abundance of Calcium]; IL13 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium]; IL4 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium]; IL6ST protein promotes the reaction [IL11 protein results in increased abundance of Calcium]; Indomethacin inhibits the reaction [IL11 protein results in increased abundance of Calcium]; TNFRSF11B protein inhibits the reaction [IL11 protein results in increased abundance of Calcium] |
CTD |
PMID:12110441 |
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NCBI chr19:55,364,382...55,370,463
Ensembl chr19:55,364,382...55,370,463
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G |
IL13 |
interleukin 13 |
multiple interactions |
ISO |
IL13 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium] |
CTD |
PMID:12110441 |
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NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
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G |
IL1B |
interleukin 1 beta |
multiple interactions |
ISO EXP |
KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]] |
CTD |
PMID:23747339 |
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NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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G |
IL4 |
interleukin 4 |
multiple interactions |
ISO |
IL4 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium] |
CTD |
PMID:12110441 |
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NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
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G |
IL6 |
interleukin 6 |
multiple interactions increases expression |
EXP |
Calcimycin inhibits the reaction [Calcium promotes the reaction [Histamine results in increased expression of IL6 protein]]; Calcium promotes the reaction [Histamine results in increased expression of IL6 protein]; Edetic Acid inhibits the reaction [Calcium promotes the reaction [Histamine results in increased expression of IL6 protein]] Calcium results in increased expression of IL6 mRNA |
CTD |
PMID:11238657 PMID:20682585 |
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NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
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G |
IL6ST |
interleukin 6 cytokine family signal transducer |
multiple interactions |
ISO |
IL6ST protein promotes the reaction [IL11 protein results in increased abundance of Calcium] |
CTD |
PMID:12110441 |
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NCBI chr 5:55,935,095...55,994,963
Ensembl chr 5:55,935,095...55,995,022
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G |
ILF3 |
interleukin enhancer binding factor 3 |
multiple interactions |
EXP |
Calcium affects the reaction [Vanadates results in increased activity of ILF3 protein] |
CTD |
PMID:10623810 |
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NCBI chr19:10,654,346...10,692,400
Ensembl chr19:10,654,304...10,692,400
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G |
INS-IGF2 |
INS-IGF2 readthrough |
multiple interactions |
ISO |
Calcium deficiency inhibits the reaction [[Glucose co-treated with INS1 protein] results in increased secretion of LEP protein]; Calcium deficiency inhibits the reaction [INS1 protein results in increased activity of SLC2A1 protein]; Chromium affects the reaction [INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; chromium tripicolinate affects the reaction [INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; INS1 protein affects the reaction [Chromium affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; INS1 protein affects the reaction [chromium tripicolinate affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]] |
CTD |
PMID:9446840 PMID:10780946 PMID:10970766 |
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NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209
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G |
IQGAP1 |
IQ motif containing GTPase activating protein 1 |
multiple interactions |
ISO |
Calcium promotes the reaction [PAFAH1B1 protein binds to IQGAP1 protein binds to CDC42 protein] |
CTD |
PMID:16369480 |
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NCBI chr15:90,388,242...90,502,239
Ensembl chr15:90,388,242...90,502,239
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G |
ITGA2 |
integrin subunit alpha 2 |
multiple interactions |
ISO |
ITGA2 protein promotes the reaction [[Dinoprostone co-treated with Serotonin] results in increased import of Calcium]; TRPV4 protein promotes the reaction [ITGA2 protein promotes the reaction [[Dinoprostone co-treated with Serotonin] results in increased import of Calcium]] |
CTD |
PMID:18234883 |
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NCBI chr 5:52,989,352...53,094,779
Ensembl chr 5:52,989,340...53,094,779
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G |
ITGB1BP2 |
integrin subunit beta 1 binding protein 2 |
multiple interactions |
EXP ISO |
Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to SUGT1 protein]] Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]] |
CTD |
PMID:23184943 |
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NCBI chr X:71,301,750...71,305,371
Ensembl chr X:71,301,750...71,305,371
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G |
ITIH1 |
inter-alpha-trypsin inhibitor heavy chain 1 |
multiple interactions |
EXP |
Calcium promotes the reaction [ITIH1 protein binds to TNFAIP6 protein] |
CTD |
PMID:16768462 |
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NCBI chr 3:52,777,599...52,792,068
Ensembl chr 3:52,777,595...52,792,068
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G |
ITIH2 |
inter-alpha-trypsin inhibitor heavy chain 2 |
multiple interactions |
EXP |
Calcium promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] |
CTD |
PMID:16768462 |
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NCBI chr10:7,703,316...7,749,520
Ensembl chr10:7,703,316...7,749,520
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G |
ITPR1 |
inositol 1,4,5-trisphosphate receptor type 1 |
multiple interactions |
EXP |
ITPR1 protein promotes the reaction [Acetaldehyde metabolite results in increased abundance of Calcium]; ITPR1 protein promotes the reaction [Ethanol metabolite results in increased abundance of Calcium] |
CTD |
PMID:17241155 |
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NCBI chr 3:4,493,348...4,847,506
Ensembl chr 3:4,493,345...4,847,506
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G |
ITPR2 |
inositol 1,4,5-trisphosphate receptor type 2 |
multiple interactions |
ISO |
2-aminoethoxydiphenyl borate inhibits the reaction [[adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium]; [adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium; xestospongin C inhibits the reaction [[adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium] |
CTD |
PMID:15201137 |
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NCBI chr12:26,335,352...26,833,194
Ensembl chr12:26,335,352...26,833,194
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G |
ITPR3 |
inositol 1,4,5-trisphosphate receptor type 3 |
affects expression |
ISO |
Calcium affects the expression of ITPR3 protein |
CTD |
PMID:10963052 |
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NCBI chr 6:33,621,322...33,696,562
Ensembl chr 6:33,620,365...33,696,574
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G |
IVL |
involucrin |
increases expression multiple interactions |
EXP |
Calcium results in increased expression of IVL mRNA NPS R-467 promotes the reaction [Calcium results in increased expression of IVL mRNA] |
CTD |
PMID:10469331 |
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NCBI chr 1:152,908,546...152,911,886
Ensembl chr 1:152,908,546...152,911,886
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G |
JAK2 |
Janus kinase 2 |
multiple interactions |
ISO |
JAK2 protein promotes the reaction [LEP protein results in increased transport of Calcium] |
CTD |
PMID:20107083 |
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NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948
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G |
KCNE1 |
potassium voltage-gated channel subfamily E regulatory subunit 1 |
increases activity multiple interactions |
ISO |
Calcium results in increased activity of KCNE1 protein W 7 inhibits the reaction [Calcium results in increased activity of KCNE1 protein] |
CTD |
PMID:1655403 |
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NCBI chr21:34,446,688...34,512,210
Ensembl chr21:34,446,688...34,512,214
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G |
KCNH2 |
potassium voltage-gated channel subfamily H member 2 |
multiple interactions |
ISO |
Nimodipine inhibits the reaction [KCNH2 protein affects the abundance of Calcium] |
CTD |
PMID:11040061 |
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NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321
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G |
KCNJ11 |
potassium inwardly rectifying channel subfamily J member 11 |
multiple interactions affects abundance |
ISO |
Dantrolene inhibits the reaction [KCNJ11 protein mutant form results in increased abundance of Calcium]; KCNJ11 protein affects the reaction [[Manganese co-treated with Dobutamine] results in increased abundance of Calcium]; W 7 inhibits the reaction [KCNJ11 protein mutant form results in increased abundance of Calcium] KCNJ11 protein affects the abundance of Calcium |
CTD |
PMID:17189350 |
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NCBI chr11:17,385,248...17,389,346
Ensembl chr11:17,365,172...17,389,331
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G |
KCNMA1 |
potassium calcium-activated channel subfamily M alpha 1 |
multiple interactions increases response to substance |
EXP ISO |
[KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium; Lithocholic Acid promotes the reaction [[KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium] KCNMA1 mRNA alternative form results in increased susceptibility to Calcium |
CTD |
PMID:22123969 PMID:28090300 |
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NCBI chr10:76,869,602...77,637,808
Ensembl chr10:76,869,601...77,638,369
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G |
KCNMB1 |
potassium calcium-activated channel subfamily M regulatory beta subunit 1 |
multiple interactions |
EXP |
[KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium; Lithocholic Acid promotes the reaction [[KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium] |
CTD |
PMID:22123969 |
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NCBI chr 5:170,374,671...170,389,367
Ensembl chr 5:170,374,671...170,389,634
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G |
KCNN2 |
potassium calcium-activated channel subfamily N member 2 |
increases activity multiple interactions |
EXP |
Calcium results in increased activity of KCNN2 protein cyclohexyl-(2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl)amine promotes the reaction [Calcium results in increased activity of KCNN2 protein] |
CTD |
PMID:17486140 |
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NCBI chr 5:114,055,978...114,496,496
Ensembl chr 5:114,055,926...114,496,500
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G |
KCNN3 |
potassium calcium-activated channel subfamily N member 3 |
multiple interactions increases activity |
EXP |
6,7-dichloro-1H-indole-2,3-dione 3-oxime promotes the reaction [Calcium results in increased activity of KCNN3 protein]; cyclohexyl-(2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl)amine promotes the reaction [Calcium results in increased activity of KCNN3 protein] |
CTD |
PMID:17486140 |
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NCBI chr 1:154,697,455...154,870,281
Ensembl chr 1:154,697,455...154,870,281
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G |
KCNN4 |
potassium calcium-activated channel subfamily N member 4 |
affects abundance multiple interactions |
EXP |
KCNN4 protein affects the abundance of Calcium KCNN4 protein affects the reaction [Calcium results in increased transport of Potassium] |
CTD |
PMID:11826162 PMID:14985237 |
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NCBI chr19:43,766,533...43,780,973
Ensembl chr19:43,766,533...43,780,976
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G |
KDR |
kinase insert domain receptor |
multiple interactions |
EXP ISO |
[VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium; TRPC6 protein promotes the reaction [[VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium] Calcium promotes the reaction [Corticosterone results in decreased expression of KDR protein] |
CTD |
PMID:14551041 PMID:21647420 |
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NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595
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G |
KHSRP |
KH-type splicing regulatory protein |
multiple interactions |
ISO |
Calcium deficiency inhibits the reaction [KHSRP protein binds to PTH 3' UTR] |
CTD |
PMID:18583400 |
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NCBI chr19:6,413,102...6,424,811
Ensembl chr19:6,413,102...6,424,811
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G |
KISS1 |
KiSS-1 metastasis suppressor |
multiple interactions |
ISO |
2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; [KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium; Flufenamic Acid inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin promotes the reaction [2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]] |
CTD |
PMID:18948403 |
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NCBI chr 1:204,190,341...204,196,491
Ensembl chr 1:204,190,341...204,196,491
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G |
KISS1R |
KISS1 receptor |
multiple interactions |
ISO |
2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; [KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium; Flufenamic Acid inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin promotes the reaction [2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]] |
CTD |
PMID:18948403 |
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NCBI chr19:917,333...921,005
Ensembl chr19:917,287...921,005
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G |
KL |
klotho |
affects abundance multiple interactions |
ISO |
KL protein affects the abundance of Calcium KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]] |
CTD |
PMID:11796525 PMID:23747339 |
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NCBI chr13:33,016,243...33,066,143
Ensembl chr13:33,016,423...33,066,143
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G |
KLK1 |
kallikrein 1 |
decreases activity |
EXP |
Calcium results in decreased activity of KLK1 protein |
CTD |
PMID:15558947 |
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NCBI chr19:50,819,146...50,823,787
Ensembl chr19:50,819,146...50,823,787
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G |
KLK8 |
kallikrein related peptidase 8 |
increases activity |
EXP |
Calcium results in increased activity of KLK8 protein |
CTD |
PMID:16800733 |
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NCBI chr19:50,996,008...51,001,604
Ensembl chr19:50,996,007...51,002,711
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G |
KNG1 |
kininogen 1 |
multiple interactions increases abundance affects abundance |
EXP ISO |
BDKRB2 protein affects the reaction [KNG1 protein affects the abundance of Calcium] KNG1 protein modified form results in increased abundance of Calcium [KNG1 protein alternative form co-treated with Calcium] results in increased secretion of CALCA protein; Calcium affects the reaction [KNG1 protein results in increased secretion of Excitatory Amino Acid Agents] B 4162 inhibits the reaction [pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]]; BDKRB2 protein affects the reaction [pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]]; CALR protein promotes the reaction [KNG1 protein modified form results in increased abundance of Calcium]; KNG1 protein affects the transport of and affects the localization of Calcium; pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium] KNG1 protein results in increased abundance of Calcium |
CTD |
PMID:7961812 PMID:8592139 PMID:10535458 PMID:12582005 PMID:16473424 PMID:17666428 PMID:18054572 More...
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NCBI chr 3:186,717,359...186,744,410
Ensembl chr 3:186,717,348...186,744,410
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G |
KRT1 |
keratin 1 |
multiple interactions increases expression |
ISO EXP |
12-Hydroxy-5,8,10,14-eicosatetraenoic Acid inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; 15-hydroxy-5,8,11,13-eicosatetraenoic acid inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; 8-hydroxyeicosatetraenoic acid promotes the reaction [Calcium results in increased expression of KRT1 mRNA]; Masoprocol inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; morin inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; Quercetin inhibits the reaction [Calcium results in increased expression of KRT1 mRNA] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of KRT1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of KRT1 protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; SB 203580 inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; SB 203580 inhibits the reaction [Calcium results in increased expression of KRT1 protein]; WNT5A protein promotes the reaction [Calcium results in increased expression of KRT1 mRNA]; WNT5A protein promotes the reaction [Calcium results in increased expression of KRT1 protein] Calcium results in increased expression of KRT1 mRNA; Calcium results in increased expression of KRT1 protein |
CTD |
PMID:12069687 PMID:21524694 PMID:24658506 |
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NCBI chr12:52,674,736...52,680,407
Ensembl chr12:52,674,736...52,680,407
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G |
LEP |
leptin |
affects abundance multiple interactions affects secretion increases transport affects expression decreases abundance |
ISO |
LEP protein affects the abundance of Calcium Calcium deficiency inhibits the reaction [[Glucose co-treated with INS1 protein] results in increased secretion of LEP protein] Calcium deficiency affects the secretion of LEP protein LEP protein results in increased transport of Calcium 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [LEP protein results in increased transport of Calcium]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [LEP protein results in increased transport of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [LEP protein results in increased transport of Calcium]; acetovanillone inhibits the reaction [LEP protein affects the abundance of Calcium]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [LEP protein results in increased transport of Calcium]; BQ 788 inhibits the reaction [LEP protein affects the abundance of Calcium]; Calcium promotes the reaction [LEP protein results in increased transport of Calcium]; cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [LEP protein affects the abundance of Calcium]; edelfosine inhibits the reaction [LEP protein results in increased transport of Calcium]; Flufenamic Acid inhibits the reaction [LEP protein results in increased transport of Calcium]; JAK2 protein promotes the reaction [LEP protein results in increased transport of Calcium]; Lanthanum promotes the reaction [LEP protein results in increased transport of Calcium]; LEP protein promotes the reaction [TRPC1 protein results in increased transport of Calcium]; LEP protein promotes the reaction [TRPC4 protein results in increased transport of Calcium]; LEP protein promotes the reaction [TRPC5 protein results in increased transport of Calcium]; wortmannin inhibits the reaction [LEP protein results in increased transport of Calcium] Calcium affects the expression of LEP mRNA LEP protein results in decreased abundance of Calcium |
CTD |
PMID:10780946 PMID:14657008 PMID:15913539 PMID:16380530 PMID:20107083 |
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NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629
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G |
LEPR |
leptin receptor |
affects expression |
ISO |
Calcium affects the expression of LEPR mRNA |
CTD |
PMID:15913539 |
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NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559
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G |
LIF |
LIF interleukin 6 family cytokine |
increases abundance |
ISO |
LIF protein results in increased abundance of Calcium |
CTD |
PMID:11073891 |
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NCBI chr22:30,240,453...30,246,759
Ensembl chr22:30,240,453...30,246,759
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G |
LORICRIN |
loricrin cornified envelope precursor protein |
increases expression multiple interactions |
EXP |
Calcium results in increased expression of LORICRIN mRNA; Calcium results in increased expression of LORICRIN protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of LORICRIN mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of LORICRIN protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; SB 203580 inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; SB 203580 inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; WNT5A protein promotes the reaction [Calcium results in increased expression of LORICRIN mRNA]; WNT5A protein promotes the reaction [Calcium results in increased expression of LORICRIN protein] |
CTD |
PMID:21524694 PMID:24658506 |
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NCBI chr 1:153,259,687...153,262,124
Ensembl chr 1:153,259,687...153,262,124
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G |
LYPLA1 |
lysophospholipase 1 |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of LYPLA1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 8:54,046,367...54,101,947
Ensembl chr 8:54,046,367...54,102,017
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G |
MAP2K1 |
mitogen-activated protein kinase kinase 1 |
multiple interactions |
ISO |
[Sumatriptan results in increased abundance of Calcium] inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA]; Calcium inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA] |
CTD |
PMID:12574409 |
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NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656
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G |
MAP2K2 |
mitogen-activated protein kinase kinase 2 |
affects expression |
ISO |
Calcium affects the expression of MAP2K2 mRNA |
CTD |
PMID:15913539 |
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NCBI chr19:4,090,321...4,124,122
Ensembl chr19:4,090,321...4,124,122
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MAPK1 |
mitogen-activated protein kinase 1 |
increases phosphorylation multiple interactions |
EXP ISO |
Calcium results in increased phosphorylation of MAPK1 protein Calcium promotes the reaction [Diclofenac results in increased phosphorylation of MAPK1 protein] Calcium affects the reaction [Ptychodiscus brevis T2 toxin affects the phosphorylation of MAPK1 protein]; Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK1 protein] Calcium deficiency inhibits the reaction [Carbachol results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
CTD |
PMID:10660688 PMID:15086530 PMID:16877402 PMID:17537980 PMID:18758753 PMID:19782052 PMID:26609140 More...
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NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
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MAPK14 |
mitogen-activated protein kinase 14 |
affects expression |
ISO |
Calcium affects the expression of MAPK14 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,782...36,111,236
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G |
MAPK3 |
mitogen-activated protein kinase 3 |
increases phosphorylation multiple interactions |
EXP ISO |
Calcium results in increased phosphorylation of MAPK3 protein Calcium promotes the reaction [Diclofenac results in increased phosphorylation of MAPK3 protein] Calcium deficiency inhibits the reaction [Carbachol results in increased phosphorylation of and results in increased activity of MAPK3 protein] Calcium affects the reaction [Ptychodiscus brevis T2 toxin affects the phosphorylation of MAPK3 protein]; Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]; Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:10660688 PMID:15086530 PMID:16877402 PMID:17537980 PMID:18758753 PMID:19782052 PMID:26609140 More...
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NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
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MAPK4 |
mitogen-activated protein kinase 4 |
affects expression |
ISO |
Calcium affects the expression of MAPK4 mRNA |
CTD |
PMID:15913539 |
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NCBI chr18:50,559,612...50,731,826
Ensembl chr18:50,560,087...50,731,826
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MARCO |
macrophage receptor with collagenous structure |
multiple interactions |
EXP |
Calcium promotes the reaction [titanium dioxide binds to MARCO protein] |
CTD |
PMID:18836211 |
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NCBI chr 2:118,942,194...118,994,660
Ensembl chr 2:118,942,194...118,994,660
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MCOLN1 |
mucolipin TRP cation channel 1 |
multiple interactions |
EXP |
[NAADP results in increased activity of MCOLN1 protein] which affects the localization of Calcium |
CTD |
PMID:21613607 |
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NCBI chr19:7,522,624...7,534,009
Ensembl chr19:7,522,624...7,534,009
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MCU |
mitochondrial calcium uniporter |
affects localization |
ISO |
MCU protein affects the localization of Calcium |
CTD |
PMID:22829870 |
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NCBI chr10:72,692,143...72,887,694
Ensembl chr10:72,692,143...72,887,694
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MGP |
matrix Gla protein |
multiple interactions affects expression affects binding |
EXP ISO |
[Calcium binds to MGP protein] which binds to and results in decreased activity of BMP4 protein; [Edetic Acid inhibits the reaction [Calcium binds to MGP protein]] inhibits the reaction [MGP protein binds to BMP4 protein]; Edetic Acid inhibits the reaction [Calcium binds to MGP protein] Calcium affects the expression of MGP mRNA |
CTD |
PMID:15913539 PMID:18369157 |
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NCBI chr12:14,880,864...14,885,854
Ensembl chr12:14,880,864...14,885,857
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MMP1 |
matrix metallopeptidase 1 |
affects expression |
EXP |
Calcium affects the expression of MMP1 mRNA; Calcium affects the expression of MMP1 protein |
CTD |
PMID:17508023 |
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NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160
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MTOR |
mechanistic target of rapamycin kinase |
multiple interactions |
ISO |
Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of MTOR protein] |
CTD |
PMID:12935885 |
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NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556
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MYBPC3 |
myosin binding protein C3 |
multiple interactions increases response to substance |
ISO |
epigallocatechin gallate inhibits the reaction [MYBPC3 gene mutant form results in increased susceptibility to Calcium] |
CTD |
PMID:27994558 |
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NCBI chr11:47,331,406...47,352,702
Ensembl chr11:47,331,406...47,352,702
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MYH7 |
myosin heavy chain 7 |
increases transport |
EXP |
MYH7 gene mutant form results in increased transport of Calcium |
CTD |
PMID:29741611 |
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NCBI chr14:23,412,740...23,435,660
Ensembl chr14:23,412,740...23,435,660
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MYL2 |
myosin light chain 2 |
multiple interactions |
EXP |
Calcium affects the reaction [MYL2 gene SNP affects the abundance of Lead] |
CTD |
PMID:28212632 |
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NCBI chr12:110,910,845...110,921,449
Ensembl chr12:110,910,819...110,921,443
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MYL3 |
myosin light chain 3 |
affects expression |
ISO |
Calcium affects the expression of MYL3 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 3:46,857,872...46,882,182
Ensembl chr 3:46,835,111...46,882,178
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MYL9 |
myosin light chain 9 |
multiple interactions affects phosphorylation decreases phosphorylation |
ISO |
[[Calcium results in increased activity of MYLK protein] which results in increased phosphorylation of MYL9 protein] which results in decreased secretion of REN protein; [CACNA1D protein results in increased uptake of Calcium] which results in increased phosphorylation of MYL9 protein; [Escin affects the susceptibility to Calcium] which results in increased phosphorylation of MYL9 protein; Glycodeoxycholic Acid inhibits the reaction [[Escin affects the susceptibility to Calcium] which results in increased phosphorylation of MYL9 protein]; Y 27632 inhibits the reaction [[Escin affects the susceptibility to Calcium] which results in increased phosphorylation of MYL9 protein] Calcium affects the phosphorylation of MYL9 protein Calcium deficiency results in decreased phosphorylation of MYL9 protein |
CTD |
PMID:7503253 PMID:9618396 PMID:17272349 PMID:29660437 |
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NCBI chr20:36,541,519...36,551,447
Ensembl chr20:36,541,497...36,551,447
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MYLK |
myosin light chain kinase |
increases activity multiple interactions |
EXP ISO |
Calcium deficiency results in increased activity of MYLK protein; Calcium results in increased activity of MYLK protein [[Calcium results in increased activity of MYLK protein] which results in increased phosphorylation of MYL9 protein] which results in decreased secretion of REN protein ML 7 inhibits the reaction [Calcium deficiency results in increased activity of MYLK protein] |
CTD |
PMID:9618396 PMID:10640419 PMID:11054866 |
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NCBI chr 3:123,610,049...123,884,332
Ensembl chr 3:123,610,049...123,884,332
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MYO1B |
myosin IB |
increases activity |
ISO |
Calcium deficiency results in increased activity of MYO1B protein |
CTD |
PMID:10419463 |
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NCBI chr 2:191,245,404...191,425,386
Ensembl chr 2:191,245,185...191,425,389
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MYO5A |
myosin VA |
affects activity |
ISO |
Calcium affects the activity of MYO5A protein |
CTD |
PMID:10660602 |
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NCBI chr15:52,307,283...52,529,050
Ensembl chr15:52,307,281...52,529,132
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NAIP |
NLR family apoptosis inhibitory protein |
decreases response to substance |
ISO |
NAIP protein results in decreased susceptibility to Calcium |
CTD |
PMID:12445469 |
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NCBI chr 5:70,968,166...71,025,339
Ensembl chr 5:70,968,166...71,025,339
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NCF1 |
neutrophil cytosolic factor 1 |
affects abundance |
ISO |
NCF1 protein affects the abundance of Calcium |
CTD |
PMID:16280459 |
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NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315
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NDUFS1 |
NADH:ubiquinone oxidoreductase core subunit S1 |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of NDUFS1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 2:206,114,817...206,159,444
Ensembl chr 2:206,114,817...206,159,509
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NEDD4 |
NEDD4 E3 ubiquitin protein ligase |
affects expression |
ISO |
Calcium affects the expression of NEDD4 mRNA |
CTD |
PMID:15913539 |
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NCBI chr15:55,826,917...55,993,612
Ensembl chr15:55,826,922...55,993,660
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NEDD4L |
NEDD4 like E3 ubiquitin protein ligase |
multiple interactions |
ISO |
[NEDD4L gene mutant form results in increased susceptibility to Sodium, Dietary] which results in increased abundance of Calcium; Thiazides inhibits the reaction [[NEDD4L gene mutant form results in increased susceptibility to Sodium, Dietary] which results in increased abundance of Calcium] |
CTD |
PMID:23348737 |
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NCBI chr18:58,044,226...58,401,540
Ensembl chr18:58,044,226...58,401,540
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NEFL |
neurofilament light chain |
multiple interactions |
ISO |
Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of NEFL protein]; calpeptin inhibits the reaction [Calcium results in increased degradation of NEFL protein]; Indomethacin inhibits the reaction [Calcium results in increased degradation of NEFL protein] |
CTD |
PMID:11071371 PMID:21879721 |
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NCBI chr 8:24,950,955...24,956,612
Ensembl chr 8:24,950,955...24,956,721
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NEFM |
neurofilament medium chain |
multiple interactions |
ISO |
Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of NEFM protein] |
CTD |
PMID:21879721 |
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NCBI chr 8:24,913,761...24,919,093
Ensembl chr 8:24,913,758...24,919,098
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NEK9 |
NIMA related kinase 9 |
affects expression |
ISO |
Calcium affects the expression of NEK9 mRNA |
CTD |
PMID:15913539 |
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NCBI chr14:75,079,353...75,127,202
Ensembl chr14:75,079,353...75,127,344
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NF1 |
neurofibromin 1 |
decreases transport |
ISO |
NF1 protein results in decreased transport of Calcium |
CTD |
PMID:21949590 |
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NCBI chr17:31,094,927...31,377,677
Ensembl chr17:31,094,927...31,382,116
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NFATC2 |
nuclear factor of activated T cells 2 |
multiple interactions |
ISO |
4-methyl-4'-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)-1,2,3-thiadiazole-5-carboxanilide inhibits the reaction [[Muscarine co-treated with Calcium] affects the localization of NFATC2 protein]; 4-methyl-4'-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)-1,2,3-thiadiazole-5-carboxanilide inhibits the reaction [[Thapsigargin co-treated with Calcium] affects the localization of NFATC2 protein]; [Muscarine co-treated with Calcium] affects the localization of NFATC2 protein; [Thapsigargin co-treated with Calcium] affects the localization of NFATC2 protein |
CTD |
PMID:24990931 |
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NCBI chr20:51,386,963...51,562,839
Ensembl chr20:51,386,957...51,562,831
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NFE2L2 |
NFE2 like bZIP transcription factor 2 |
increases abundance |
ISO |
NFE2L2 gene mutant form results in increased abundance of Calcium |
CTD |
PMID:29618784 |
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NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
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NFKBIA |
NFKB inhibitor alpha |
affects expression multiple interactions |
ISO EXP |
Calcium affects the expression of NFKBIA mRNA Calcium affects the reaction [Morphine inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]] |
CTD |
PMID:15913539 PMID:24068670 |
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NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
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NGB |
neuroglobin |
affects transport |
EXP |
NGB protein affects the transport of Calcium |
CTD |
PMID:19154338 |
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NCBI chr14:77,265,483...77,271,206
Ensembl chr14:77,265,483...77,271,206
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NGF |
nerve growth factor |
multiple interactions increases uptake |
ISO |
[NGF protein co-treated with 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester] results in increased uptake of Calcium; [NGF protein co-treated with Adenosine Triphosphate] results in increased uptake of Calcium; cadmium acetate inhibits the reaction [NGF protein results in increased uptake of Calcium]; Cadmium inhibits the reaction [NGF protein results in increased uptake of Calcium]; calmidazolium inhibits the reaction [NGF protein results in increased uptake of Calcium]; Fluphenazine inhibits the reaction [NGF protein results in increased uptake of Calcium]; Nifedipine inhibits the reaction [NGF protein results in increased uptake of Calcium]; Okadaic Acid promotes the reaction [NGF protein results in increased uptake of Calcium]; Staurosporine inhibits the reaction [NGF protein results in increased uptake of Calcium] |
CTD |
PMID:1374475 |
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NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770
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G |
NHERF4 |
NHERF family PDZ scaffold protein 4 |
multiple interactions |
ISO |
[[USP2 gene mutant form results in increased expression of NHERF4 protein] which results in increased activity of TRPV6 protein] which results in increased uptake of Calcium |
CTD |
PMID:26756164 |
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NCBI chr11:119,185,475...119,190,213
Ensembl chr11:119,185,457...119,190,223
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NOA1 |
nitric oxide associated 1 |
multiple interactions |
ISO |
[Tamoxifen results in increased abundance of Calcium] which results in increased activity of NOA1 protein |
CTD |
PMID:17283165 |
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NCBI chr 4:56,963,350...56,977,606
Ensembl chr 4:56,963,350...56,977,606
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NOS1 |
nitric oxide synthase 1 |
multiple interactions |
ISO |
[Calcium binds to CALM1 protein] promotes the reaction [NOS1 protein results in increased chemical synthesis of Nitric Oxide]; [Calcium binds to CALM1 protein] which binds to and affects the folding of and results in increased activity of NOS1 protein |
CTD |
PMID:17098364 |
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NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
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G |
NOS3 |
nitric oxide synthase 3 |
affects response to substance increases activity multiple interactions |
ISO EXP |
NOS3 protein affects the susceptibility to Calcium Calcium results in increased activity of NOS3 protein Calcium affects the reaction [Polycyclic Aromatic Hydrocarbons results in increased expression of and results in increased activity of NOS3 protein]; Calcium deficiency inhibits the reaction [Digitoxin results in increased activity of NOS3 protein]; Calcium deficiency inhibits the reaction [ginsenoside Re results in increased phosphorylation of NOS3 protein] |
CTD |
PMID:15183461 PMID:17403420 PMID:17490654 PMID:19380615 PMID:19446813 PMID:22244921 More...
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NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
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G |
NOX1 |
NADPH oxidase 1 |
multiple interactions |
ISO |
1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid inhibits the reaction [NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]]; NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]] |
CTD |
PMID:24912985 |
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NCBI chr X:100,843,324...100,874,359
Ensembl chr X:100,843,324...100,874,359
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NPPC |
natriuretic peptide C |
increases uptake multiple interactions |
ISO |
NPPC protein results in increased uptake of Calcium Ammonia inhibits the reaction [NPPC protein results in increased uptake of Calcium]; Nimodipine inhibits the reaction [NPPC protein results in increased uptake of Calcium] |
CTD |
PMID:18222015 |
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NCBI chr 2:231,921,809...231,926,396
Ensembl chr 2:231,921,809...231,926,396
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NPR1 |
natriuretic peptide receptor 1 |
affects expression |
ISO |
Calcium affects the expression of NPR1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 1:153,678,688...153,693,992
Ensembl chr 1:153,678,688...153,693,992
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G |
NR0B2 |
nuclear receptor subfamily 0 group B member 2 |
affects expression |
ISO |
Calcium affects the expression of NR0B2 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 1:26,911,489...26,913,975
Ensembl chr 1:26,911,489...26,913,975
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G |
NR1D2 |
nuclear receptor subfamily 1 group D member 2 |
affects expression |
ISO |
Calcium affects the expression of NR1D2 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 3:23,945,286...23,980,617
Ensembl chr 3:23,945,286...23,980,617
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G |
NRXN1 |
neurexin 1 |
multiple interactions |
ISO |
Calcium affects the reaction [alpha-latrotoxin binds to NRXN1 protein]; Calcium affects the reaction [black widow spider venom binds to NRXN1 protein] |
CTD |
PMID:9430716 |
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NCBI chr 2:49,918,503...51,032,132
Ensembl chr 2:49,918,503...51,225,575
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G |
NUCB2 |
nucleobindin 2 |
multiple interactions |
ISO |
KT 5720 inhibits the reaction [NUCB2 protein results in increased import of Calcium] |
CTD |
PMID:17627999 |
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NCBI chr11:17,276,739...17,349,980
Ensembl chr11:17,208,153...17,349,980
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G |
OCLN |
occludin |
multiple interactions |
EXP |
Calcium deficiency inhibits the reaction [TJP1 protein binds to OCLN protein] |
CTD |
PMID:11054866 |
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NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104
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G |
OPRM1 |
opioid receptor mu 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcium] inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]] |
CTD |
PMID:18652891 |
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NCBI chr 6:154,010,496...154,246,867
Ensembl chr 6:154,010,496...154,246,867
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OR1D2 |
olfactory receptor family 1 subfamily D member 2 |
multiple interactions |
EXP |
[bourgeonal binds to and results in increased activity of OR1D2 protein] which results in increased abundance of Calcium |
CTD |
PMID:21454470 |
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NCBI chr17:3,088,484...3,104,422
Ensembl chr17:3,088,484...3,104,422
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G |
OR5D18 |
olfactory receptor family 5 subfamily D member 18 |
multiple interactions |
ISO |
[ethyl vanillin binds to and results in increased activity of OR5D18 protein] which results in increased transport of Calcium; [Eugenol binds to and results in increased activity of OR5D18 protein] which results in increased transport of Calcium; [Eugenol binds to OR5D18 protein] which results in increased transport of Calcium; [isomethyleugenol binds to and results in decreased activity of OR5D18 protein] which results in decreased transport of Calcium; isomethyleugenol inhibits the reaction [[Eugenol binds to OR5D18 protein] which results in increased transport of Calcium] |
CTD |
PMID:14685265 PMID:15716417 |
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NCBI chr11:55,819,630...55,820,571
Ensembl chr11:55,819,630...55,820,571
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G |
ORAI1 |
ORAI calcium release-activated calcium modulator 1 |
multiple interactions increases uptake |
ISO |
[Calcium affects the activity of and affects the localization of STIM1 protein] which affects the activity of ORAI1 protein ORAI1 protein results in increased uptake of Calcium |
CTD |
PMID:23212906 PMID:24990931 |
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NCBI chr12:121,626,530...121,643,109
Ensembl chr12:121,626,509...121,643,218
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G |
OXT |
oxytocin/neurophysin I prepropeptide |
multiple interactions |
EXP ISO |
OXT protein promotes the reaction [TRPC3 protein results in increased transport of Calcium] [Thapsigargin results in increased transport of Calcium] which results in increased secretion of OXT protein |
CTD |
PMID:12700192 PMID:22028774 |
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NCBI chr20:3,071,620...3,072,517
Ensembl chr20:3,071,620...3,072,517
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G |
P2RX3 |
purinergic receptor P2X 3 |
multiple interactions |
EXP |
[alpha,beta-methyleneadenosine 5'-triphosphate binds to and results in increased activity of P2RX3 protein] which results in increased abundance of Calcium; Trichloroethylene inhibits the reaction [[alpha,beta-methyleneadenosine 5'-triphosphate binds to and results in increased activity of P2RX3 protein] which results in increased abundance of Calcium] |
CTD |
PMID:12694404 |
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NCBI chr11:57,335,950...57,372,396
Ensembl chr11:57,338,352...57,372,396
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G |
P2RX7 |
purinergic receptor P2X 7 |
multiple interactions |
EXP |
[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium; KN 62 inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium]; protoberberine analog inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium] |
CTD |
PMID:21320518 |
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NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032
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G |
P2RY1 |
purinergic receptor P2Y1 |
multiple interactions |
EXP ISO |
[Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein] which results in increased abundance of Calcium; Calcium affects the reaction [P2RY1 protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; Trichloroethylene inhibits the reaction [[Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein] which results in increased abundance of Calcium] [N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate binds to and results in decreased activity of P2RY1 protein] inhibits the reaction [Adenosine Triphosphate results in increased uptake of Calcium] |
CTD |
PMID:12694404 PMID:16236484 PMID:16973929 |
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NCBI chr 3:152,835,131...152,841,439
Ensembl chr 3:152,835,131...152,841,439
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G |
P2RY2 |
purinergic receptor P2Y2 |
multiple interactions affects response to substance |
EXP ISO |
[Adenosine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Calcium P2RY2 protein affects the susceptibility to Calcium [Adenosine Triphosphate results in increased activity of P2RY2 protein] which results in increased uptake of Calcium; Go 6976 promotes the reaction [P2RY2 protein results in increased uptake of Calcium]; Tetradecanoylphorbol Acetate inhibits the reaction [P2RY2 protein results in increased uptake of Calcium] |
CTD |
PMID:11527950 PMID:17003265 PMID:18343036 |
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NCBI chr11:73,218,281...73,242,427
Ensembl chr11:73,218,281...73,242,427
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G |
P2RY4 |
pyrimidinergic receptor P2Y4 |
multiple interactions |
EXP |
[Adenosine Triphosphate binds to and results in increased activity of P2RY4 protein] which results in increased abundance of Calcium; Trichloroethylene inhibits the reaction [[Adenosine Triphosphate binds to and results in increased activity of P2RY4 protein] which results in increased abundance of Calcium] |
CTD |
PMID:12694404 |
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NCBI chr X:70,258,166...70,260,204
Ensembl chr X:70,258,166...70,260,204
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G |
P4HB |
prolyl 4-hydroxylase subunit beta |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of P4HB mRNA |
CTD |
PMID:15913539 |
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NCBI chr17:81,843,166...81,860,535
Ensembl chr17:81,843,159...81,860,856
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G |
PAFAH1B1 |
platelet activating factor acetylhydrolase 1b regulatory subunit 1 |
increases abundance multiple interactions |
EXP ISO |
PAFAH1B1 protein results in increased abundance of Calcium Calcium promotes the reaction [PAFAH1B1 protein binds to IQGAP1 protein binds to CDC42 protein] PKD1 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium]; PKD2 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium] |
CTD |
PMID:15001556 PMID:16369480 |
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NCBI chr17:2,593,183...2,685,615
Ensembl chr17:2,593,210...2,685,615
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G |
PARG |
poly(ADP-ribose) glycohydrolase |
multiple interactions |
ISO |
PARG protein promotes the reaction [Hydrogen Peroxide results in increased uptake of Calcium] |
CTD |
PMID:20878536 |
|
NCBI chr10:49,818,279...49,942,027
Ensembl chr10:49,818,279...49,970,203
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G |
PARP1 |
poly(ADP-ribose) polymerase 1 |
multiple interactions |
ISO |
PARP1 protein promotes the reaction [Hydrogen Peroxide results in increased uptake of Calcium] |
CTD |
PMID:20878536 |
|
NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
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G |
PASK |
PAS domain containing serine/threonine kinase |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of PASK mRNA |
CTD |
PMID:15913539 |
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NCBI chr 2:241,106,099...241,150,347
Ensembl chr 2:241,106,099...241,150,264
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G |
PAX6 |
paired box 6 |
affects expression |
ISO |
Calcium affects the expression of PAX6 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr11:31,789,026...31,817,961
Ensembl chr11:31,784,779...31,817,961
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G |
PAX8 |
paired box 8 |
affects expression |
ISO |
Calcium affects the expression of PAX8 mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 2:113,215,997...113,278,921
Ensembl chr 2:113,215,997...113,278,921
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G |
PCDH19 |
protocadherin 19 |
affects binding |
EXP |
Calcium binds to PCDH19 protein |
CTD |
PMID:18469813 |
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NCBI chr X:100,291,644...100,410,273
Ensembl chr X:100,291,644...100,410,273
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G |
PDGFB |
platelet derived growth factor subunit B |
increases import |
EXP |
PDGFB protein results in increased import of Calcium |
CTD |
PMID:19576918 |
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NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982
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G |
PDK1 |
pyruvate dehydrogenase kinase 1 |
multiple interactions affects abundance |
ISO EXP |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester affects the reaction [PDK1 protein affects the abundance of Calcium]; [PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium; Adenosine Triphosphate promotes the reaction [PDK1 protein affects the abundance of Calcium]; PDK1 protein affects the reaction [Thapsigargin affects the abundance of Calcium]; tubacin affects the reaction [[PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium]; tubacin affects the reaction [PDK1 protein affects the abundance of Calcium]; tubacin inhibits the reaction [PDK1 protein affects the reaction [Thapsigargin affects the abundance of Calcium]] PDK1 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:28634229 PMID:28887310 |
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NCBI chr 2:172,555,373...172,724,312
Ensembl chr 2:172,555,373...172,608,669
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G |
PGP |
phosphoglycolate phosphatase |
decreases activity |
ISO |
Calcium results in decreased activity of PGP protein |
CTD |
PMID:24338473 |
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NCBI chr16:2,211,593...2,214,840
Ensembl chr16:2,211,593...2,214,840
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G |
PICK1 |
protein interacting with PRKCA 1 |
multiple interactions |
ISO |
Calcium affects the reaction [PICK1 protein binds to AGO2 protein]; Calcium deficiency inhibits the reaction [Excitatory Amino Acid Agonists inhibits the reaction [PICK1 protein binds to AGO2 protein]]; Calcium promotes the reaction [PICK1 protein binds to GRIA2 protein] |
CTD |
PMID:28404816 |
|
NCBI chr22:38,057,255...38,075,701
Ensembl chr22:38,056,311...38,075,701
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G |
PIK3CB |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
affects transport |
ISO |
PIK3CB protein affects the transport of Calcium |
CTD |
PMID:11597992 |
|
NCBI chr 3:138,652,698...138,834,928
Ensembl chr 3:138,652,698...138,834,928
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G |
PIK3CD |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta |
affects transport |
ISO |
PIK3CD protein affects the transport of Calcium |
CTD |
PMID:16179367 |
|
NCBI chr 1:9,627,258...9,729,114
Ensembl chr 1:9,629,889...9,729,114
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G |
PIP5K1B |
phosphatidylinositol-4-phosphate 5-kinase type 1 beta |
affects expression |
ISO |
Calcium affects the expression of PIP5K1B mRNA |
CTD |
PMID:15913539 |
|
NCBI chr 9:68,705,240...69,009,176
Ensembl chr 9:68,705,240...69,009,176
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G |
PKD1 |
polycystin 1, transient receptor potential channel interacting |
multiple interactions |
EXP ISO |
PKD1 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium] PKD1 protein affects the reaction [Caffeine affects the abundance of Calcium]; PKD1 protein affects the reaction [Thapsigargin affects the abundance of Calcium] |
CTD |
PMID:15001556 PMID:18679710 |
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NCBI chr16:2,088,708...2,135,898
Ensembl chr16:2,088,708...2,135,898
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G |
PKD2 |
polycystin 2, transient receptor potential cation channel |
increases transport multiple interactions |
EXP ISO |
PKD2 protein results in increased transport of Calcium PKD2 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium] IFT88 protein affects the reaction [PKD2 protein results in increased uptake of Calcium] |
CTD |
PMID:15001556 PMID:15100357 PMID:16396941 |
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NCBI chr 4:88,007,635...88,077,777
Ensembl chr 4:88,007,635...88,077,777
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G |
PKLR |
pyruvate kinase L/R |
multiple interactions |
ISO |
Calcium inhibits the reaction [Phenylephrine results in decreased activity of PKLR protein] |
CTD |
PMID:747652 |
|
NCBI chr 1:155,289,293...155,308,654
Ensembl chr 1:155,289,293...155,301,438
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G |
PLA2G1B |
phospholipase A2 group IB |
multiple interactions increases abundance |
EXP |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[PLA2G1B protein results in increased abundance of Calcium] which results in increased expression of CXCL8 protein]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [PLA2G1B protein results in increased abundance of Calcium]; [PLA2G1B protein results in increased abundance of Calcium] which results in increased expression of CXCL8 protein |
CTD |
PMID:15528384 |
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NCBI chr12:120,322,115...120,327,779
Ensembl chr12:120,322,115...120,327,779
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G |
PLA2G2A |
phospholipase A2 group IIA |
increases uptake multiple interactions |
ISO |
PLA2G2A protein results in increased uptake of Calcium BQ 788 inhibits the reaction [EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium]]; EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium] |
CTD |
PMID:15695168 |
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NCBI chr 1:19,975,431...19,980,434
Ensembl chr 1:19,975,431...19,980,416
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G |
PLA2G6 |
phospholipase A2 group VI |
increases activity multiple interactions |
ISO |
Calcium deficiency results in increased activity of PLA2G6 protein 6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2H-pyran-2-one inhibits the reaction [[Lipopolysaccharides results in increased expression of and results in increased activity of PLA2G6 protein] which results in increased susceptibility to Calcium]; [Lipopolysaccharides results in increased expression of and results in increased activity of PLA2G6 protein] which results in increased susceptibility to Calcium |
CTD |
PMID:17885217 PMID:21178110 |
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NCBI chr22:38,111,495...38,181,830
Ensembl chr22:38,111,495...38,214,778
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G |
PLCG2 |
phospholipase C gamma 2 |
multiple interactions |
EXP |
Calcium promotes the reaction [PLCG2 protein mutant form results in increased chemical synthesis of Inositol Phosphates]; Calcium promotes the reaction [PLCG2 protein results in increased chemical synthesis of Inositol Phosphates] |
CTD |
PMID:27542411 |
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NCBI chr16:81,779,291...81,962,685
Ensembl chr16:81,779,279...81,962,685
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G |
PNOC |
prepronociceptin |
decreases abundance |
ISO |
PNOC protein results in decreased abundance of Calcium |
CTD |
PMID:21039959 |
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NCBI chr 8:28,316,988...28,343,351
Ensembl chr 8:28,316,986...28,343,355
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G |
PON1 |
paraoxonase 1 |
increases activity multiple interactions |
EXP ISO |
Calcium results in increased activity of PON1 protein [Calcium results in increased activity of PON1 protein] which affects the susceptibility to O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate; [Calcium results in increased activity of PON1 protein] which affects the susceptibility to oxamyl; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Aldicarb; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to methylparaoxon; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Paraoxon [Calcium co-treated with 1,2-dioleoyl-sn-glycero-3-phosphoglycerol] results in increased stability of PON1 protein; [Calcium co-treated with Oleic Acid] results in increased stability of PON1 protein; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Aldicarb; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to methylparaoxon; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to oxamyl; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Paraoxon; Calcium promotes the reaction [Oleic Acid inhibits the reaction [4-hydroxymercuribenzoate results in decreased activity of PON1 protein]] |
CTD |
PMID:12871208 PMID:27132127 |
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NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
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G |
PON2 |
paraoxonase 2 |
affects abundance multiple interactions |
EXP |
PON2 gene polymorphism affects the abundance of Calcium Calcium inhibits the reaction [lead acetate results in decreased activity of PON2 protein] |
CTD |
PMID:16141008 PMID:22271317 |
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NCBI chr 7:95,404,862...95,435,028
Ensembl chr 7:95,404,862...95,435,329
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G |
POU6F1 |
POU class 6 homeobox 1 |
affects expression |
ISO |
Calcium affects the expression of POU6F1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr12:51,186,936...51,218,062
Ensembl chr12:51,186,936...51,218,062
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G |
PPARA |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
[GW 7647 binds to and results in increased activity of PPARA protein] affects the reaction [Glucose affects the abundance of Calcium]; [Oleylethanolamide binds to and results in increased activity of PPARA protein] affects the reaction [Glucose affects the abundance of Calcium]; [pirinixic acid binds to and results in increased activity of PPARA protein] affects the reaction [Glucose affects the abundance of Calcium] |
CTD |
PMID:19017711 |
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NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
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G |
PPP1CA |
protein phosphatase 1 catalytic subunit alpha |
affects expression |
ISO |
Calcium affects the expression of PPP1CA mRNA |
CTD |
PMID:15913539 |
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NCBI chr11:67,398,183...67,401,858
Ensembl chr11:67,398,181...67,421,183
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G |
PPP1CB |
protein phosphatase 1 catalytic subunit beta |
affects expression |
ISO |
Calcium affects the expression of PPP1CB mRNA |
CTD |
PMID:15913539 |
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NCBI chr 2:28,751,604...28,802,940
Ensembl chr 2:28,751,640...28,802,940
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G |
PPP1R15A |
protein phosphatase 1 regulatory subunit 15A |
multiple interactions |
ISO |
[Egtazic Acid co-treated with Calcium deficiency] results in increased expression of PPP1R15A mRNA |
CTD |
PMID:9878749 |
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NCBI chr19:48,872,421...48,876,058
Ensembl chr19:48,872,212...48,876,059
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G |
PPP2CA |
protein phosphatase 2 catalytic subunit alpha |
affects abundance affects transport |
ISO |
PPP2CA protein affects the abundance of Calcium PPP2CA protein affects the transport of Calcium |
CTD |
PMID:15247211 |
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NCBI chr 5:134,194,332...134,226,073
Ensembl chr 5:134,194,035...134,226,073
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G |
PPP3R1 |
protein phosphatase 3 regulatory subunit B, alpha |
multiple interactions affects response to substance |
ISO |
PPP3R1 gene mutant form inhibits the reaction [ATP2A2 protein affects the transport of Calcium]; PPP3R1 gene mutant form inhibits the reaction [SLC8A1 protein affects the transport of Calcium] PPP3R1 gene mutant form affects the susceptibility to Calcium |
CTD |
PMID:19700627 |
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NCBI chr 2:68,178,857...68,252,532
Ensembl chr 2:68,178,857...68,256,237
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G |
PRDX6 |
peroxiredoxin 6 |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of PRDX6 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 1:173,477,335...173,488,815
Ensembl chr 1:173,477,330...173,488,815
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G |
PRKCA |
protein kinase C alpha |
multiple interactions increases response to substance |
ISO |
[Tretinoin co-treated with Calcium] results in increased activity of PRKCA protein PRKCA protein results in increased susceptibility to Calcium |
CTD |
PMID:12388232 PMID:16114872 |
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NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743
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G |
PRKCB |
protein kinase C beta |
multiple interactions |
ISO |
Calcium inhibits the reaction [Chlordecone results in increased activity of PRKCB protein]; Calcium inhibits the reaction [Dicofol results in increased activity of PRKCB protein] |
CTD |
PMID:1724372 |
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NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611
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G |
PRKCD |
protein kinase C delta |
affects expression |
ISO |
Calcium affects the expression of PRKCD mRNA |
CTD |
PMID:15913539 |
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NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717
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G |
PRKCE |
protein kinase C epsilon |
multiple interactions increases phosphorylation affects response to substance |
ISO EXP |
PRKCE protein affects the reaction [Oxygen deficiency results in increased abundance of Calcium] Calcium results in increased phosphorylation of PRKCE protein chelerythrine inhibits the reaction [Calcium results in increased phosphorylation of PRKCE protein]; PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]] PRKCE protein affects the susceptibility to Calcium |
CTD |
PMID:15242976 PMID:16793902 PMID:17087917 PMID:21562303 |
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NCBI chr 2:45,651,279...46,187,990
Ensembl chr 2:45,651,345...46,187,990
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G |
PRKCG |
protein kinase C gamma |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcium] inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]] |
CTD |
PMID:18652891 |
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NCBI chr19:53,881,094...53,907,652
Ensembl chr19:53,879,190...53,907,652
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G |
PRKD1 |
protein kinase D1 |
multiple interactions |
EXP ISO |
PRKD1 promotes the reaction [Capsaicin results in increased uptake of Calcium] PRKD1 mutant form inhibits the reaction [Capsaicin results in increased uptake of Calcium] |
CTD |
PMID:15471852 |
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NCBI chr14:29,576,479...29,927,847
Ensembl chr14:29,576,479...30,191,898
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G |
PRKG1 |
protein kinase cGMP-dependent 1 |
increases response to substance |
ISO |
PRKG1 protein results in increased susceptibility to Calcium |
CTD |
PMID:16533816 |
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NCBI chr10:50,990,888...52,298,350
Ensembl chr10:50,990,888...52,298,423
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G |
PRL |
prolactin |
multiple interactions |
EXP |
Calcium inhibits the reaction [PRL protein binds to PRLR protein] |
CTD |
PMID:6197504 |
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NCBI chr 6:22,287,246...22,302,835
Ensembl chr 6:22,287,244...22,302,826
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G |
PRLR |
prolactin receptor |
affects expression multiple interactions |
ISO EXP |
Calcium affects the expression of PRLR mRNA Calcium inhibits the reaction [PRL protein binds to PRLR protein] |
CTD |
PMID:6197504 PMID:15913539 |
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NCBI chr 5:35,048,756...35,230,487
Ensembl chr 5:35,048,756...35,230,487
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G |
PROK2 |
prokineticin 2 |
multiple interactions increases abundance |
ISO |
PROKR1 protein affects the reaction [PROK2 protein results in increased abundance of Calcium] |
CTD |
PMID:16793879 PMID:17107623 |
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NCBI chr 3:71,771,655...71,785,148
Ensembl chr 3:71,771,655...71,785,206
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G |
PROKR1 |
prokineticin receptor 1 |
multiple interactions |
ISO |
PROKR1 protein affects the reaction [Capsaicin results in increased abundance of Calcium]; PROKR1 protein affects the reaction [PROK2 protein results in increased abundance of Calcium] |
CTD |
PMID:16793879 |
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NCBI chr 2:68,643,579...68,658,251
Ensembl chr 2:68,643,579...68,658,251
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G |
PTAFR |
platelet activating factor receptor |
multiple interactions |
ISO |
RGS4 protein inhibits the reaction [PTAFR protein affects the localization of and affects the abundance of Calcium] |
CTD |
PMID:11297424 |
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NCBI chr 1:28,147,166...28,193,856
Ensembl chr 1:28,147,166...28,193,936
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G |
PTGDR2 |
prostaglandin D2 receptor 2 |
multiple interactions |
EXP |
PTGDR2 protein affects the abundance of and affects the localization of Calcium |
CTD |
PMID:16256979 |
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NCBI chr11:60,850,933...60,855,950
Ensembl chr11:60,850,933...60,855,950
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G |
PTGER1 |
prostaglandin E receptor 1 |
multiple interactions increases abundance |
ISO |
17-phenyltrinorprostaglandin E2 inhibits the reaction [PTGER1 protein results in increased abundance of Calcium] |
CTD |
PMID:11809688 |
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NCBI chr19:14,472,466...14,475,354
Ensembl chr19:14,472,466...14,475,354
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G |
PTGER3 |
prostaglandin E receptor 3 |
multiple interactions |
ISO |
PTGER3 protein affects the reaction [Dinoprostone results in decreased transport of Calcium]; PTGER3 protein affects the reaction [ONO AE 248 results in decreased transport of Calcium] |
CTD |
PMID:12535167 |
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NCBI chr 1:70,852,358...71,047,816
Ensembl chr 1:70,852,353...71,047,816
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G |
PTGIR |
prostaglandin I2 receptor |
multiple interactions |
EXP |
[cicaprost results in increased activity of PTGIR protein] which results in increased abundance of Calcium |
CTD |
PMID:11895442 |
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NCBI chr19:46,610,687...46,625,089
Ensembl chr19:46,620,468...46,625,089
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G |
PTGS1 |
prostaglandin-endoperoxide synthase 1 |
affects expression |
ISO |
Calcium affects the expression of PTGS1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703
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G |
PTGS2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
EXP ISO |
Calcium affects the reaction [bisperoxovanadium results in increased expression of PTGS2 mRNA] Calcium deficiency inhibits the reaction [Serotonin results in increased expression of PTGS2 mRNA] Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA] |
CTD |
PMID:12493747 PMID:19782052 PMID:21262218 |
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NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
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G |
PTH |
parathyroid hormone |
multiple interactions increases stability increases abundance decreases abundance affects metabolic processing decreases expression |
EXP ISO |
[Calcitriol co-treated with Calcium] results in decreased expression of PTH protein; [Cholecalciferol co-treated with Calcium] results in decreased expression of PTH protein Calcium deficiency results in increased stability of PTH mRNA Calcium affects the reaction [Aluminum Compounds results in decreased expression of PTH mRNA]; Calcium affects the reaction [Aluminum Compounds results in decreased secretion of PTH protein]; Calcium affects the reaction [Calcitriol results in decreased expression of PTH mRNA]; Calcium affects the reaction [Calcitriol results in decreased secretion of PTH protein]; Calcium deficiency inhibits the reaction [KHSRP protein binds to PTH 3' UTR]; Calcium deficiency promotes the reaction [HNRNPD protein binds to PTH 3' UTR] PTH protein modified form results in increased abundance of Calcium PTH protein results in decreased abundance of Calcium PTH protein affects the metabolism of Calcium Calcium results in decreased expression of PTH protein |
CTD |
PMID:80633 PMID:6330156 PMID:15891005 PMID:16094769 PMID:16316325 PMID:17476578 PMID:18583400 More...
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NCBI chr11:13,492,054...13,496,181
Ensembl chr11:13,492,054...13,496,181
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G |
PTH1R |
parathyroid hormone 1 receptor |
affects expression |
ISO |
Calcium affects the expression of PTH1R mRNA |
CTD |
PMID:15913539 |
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NCBI chr 3:46,877,721...46,903,799
Ensembl chr 3:46,877,721...46,903,799
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G |
PTK2B |
protein tyrosine kinase 2 beta |
multiple interactions |
EXP ISO |
Calcium affects the reaction [(N)-methanocarba-2MeSADP results in increased phosphorylation of PTK2B protein] Calcium affects the phosphorylation of and affects the activity of PTK2B protein |
CTD |
PMID:16236484 PMID:16877402 |
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NCBI chr 8:27,310,506...27,459,391
Ensembl chr 8:27,311,482...27,459,391
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G |
PTPN12 |
protein tyrosine phosphatase non-receptor type 12 |
affects expression |
ISO |
Calcium affects the expression of PTPN12 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 7:77,537,295...77,640,069
Ensembl chr 7:77,537,295...77,640,069
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G |
PYGL |
glycogen phosphorylase L |
multiple interactions |
ISO |
[Phenylephrine co-treated with Calcium] results in increased activity of PYGL protein; Calcium deficiency inhibits the reaction [Calcimycin results in increased activity of PYGL protein]; Glucose inhibits the reaction [[Phenylephrine co-treated with Calcium] results in increased activity of PYGL protein] |
CTD |
PMID:747652 PMID:6430282 |
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NCBI chr14:50,905,217...50,944,483
Ensembl chr14:50,857,891...50,944,483
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G |
RAB7A |
RAB7A, member RAS oncogene family |
affects expression |
ISO |
Calcium affects the expression of RAB7 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 3:128,726,183...128,814,798
Ensembl chr 3:128,693,669...128,825,942
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G |
RALGDS |
ral guanine nucleotide dissociation stimulator |
affects expression |
ISO |
Calcium affects the expression of RALGDS mRNA |
CTD |
PMID:15913539 |
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NCBI chr 9:133,097,722...133,149,210
Ensembl chr 9:133,097,720...133,149,334
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G |
RAP1A |
RAP1A, member of RAS oncogene family |
multiple interactions |
EXP |
Calcium promotes the reaction [ibandronic acid results in decreased prenylation of RAP1A protein] |
CTD |
PMID:18190680 |
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NCBI chr 1:111,542,009...111,716,691
Ensembl chr 1:111,542,218...111,716,691
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G |
RAPGEF3 |
Rap guanine nucleotide exchange factor 3 |
multiple interactions |
EXP |
RAPGEF3 protein promotes the reaction [Benzo(a)pyrene results in increased transport of Calcium] |
CTD |
PMID:22167199 |
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NCBI chr12:47,734,363...47,758,880
Ensembl chr12:47,734,363...47,771,040
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G |
RBP1 |
retinol binding protein 1 |
affects expression |
ISO |
Calcium affects the expression of RBP1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 3:139,517,438...139,539,742
Ensembl chr 3:139,517,434...139,539,829
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G |
REN |
renin |
decreases secretion multiple interactions |
ISO |
Calcium results in decreased secretion of REN protein [[Calcium results in increased activity of MYLK protein] which results in increased phosphorylation of MYL9 protein] which results in decreased secretion of REN protein; ML 7 inhibits the reaction [Calcium results in decreased secretion of REN protein] |
CTD |
PMID:9618396 |
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NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324
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G |
RGS4 |
regulator of G protein signaling 4 |
multiple interactions |
ISO |
RGS4 protein inhibits the reaction [PTAFR protein affects the localization of and affects the abundance of Calcium] |
CTD |
PMID:11297424 |
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NCBI chr 1:163,068,871...163,076,802
Ensembl chr 1:163,068,775...163,076,802
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G |
RPS3A |
ribosomal protein S3A |
affects expression |
ISO |
Calcium affects the expression of RPS3A mRNA |
CTD |
PMID:15913539 |
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NCBI chr 4:151,099,628...151,104,642
Ensembl chr 4:151,099,624...151,104,642
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G |
RPS6KB1 |
ribosomal protein S6 kinase B1 |
multiple interactions |
ISO EXP |
Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of RPS6KB1 protein] [Resveratrol results in increased abundance of Calcium] which results in decreased expression of RPS6KB1 protein modified form; dorsomorphin inhibits the reaction [[Resveratrol results in increased abundance of Calcium] which results in decreased expression of RPS6KB1 protein modified form] |
CTD |
PMID:12935885 PMID:23680031 |
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NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574
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G |
RPTOR |
regulatory associated protein of MTOR complex 1 |
multiple interactions |
EXP |
[Resveratrol results in increased abundance of Calcium] which results in increased activity of RPTOR protein modified form; dorsomorphin inhibits the reaction [[Resveratrol results in increased abundance of Calcium] which results in increased activity of RPTOR protein modified form] |
CTD |
PMID:23680031 |
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NCBI chr17:80,544,838...80,966,368
Ensembl chr17:80,544,819...80,966,371
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G |
RRAGA |
Ras related GTP binding A |
affects expression |
ISO |
Calcium affects the expression of RRAGA mRNA |
CTD |
PMID:15913539 |
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NCBI chr 9:19,049,427...19,051,025
Ensembl chr 9:19,049,427...19,051,025
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G |
RYR1 |
ryanodine receptor 1 |
multiple interactions affects abundance increases secretion increases abundance |
EXP ISO |
[Caffeine results in increased activity of RYR1 protein] which affects the localization of Calcium; [chlorocresol results in increased activity of RYR1 protein] which affects the localization of Calcium; [chlorocresol results in increased activity of RYR1 protein] which results in increased transport of Calcium; [Halothane results in increased activity of RYR1 protein] which affects the localization of Calcium; [RYR1 protein co-treated with 2,3,6,2',3',6'-hexachlorobiphenyl] affects the susceptibility to Calcium; Calcium affects the folding of [CALM1 protein binds to RYR1 protein modified form]; Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]; Dantrolene inhibits the reaction [[chlorocresol results in increased activity of RYR1 protein] which results in increased transport of Calcium]; RYR1 protein polymorphism affects the reaction [Caffeine results in increased secretion of Calcium]; RYR1 protein polymorphism affects the reaction [chlorocresol results in increased secretion of Calcium] RYR1 protein polymorphism affects the abundance of Calcium RYR1 protein mutant form results in increased secretion of Calcium RYR1 gene mutant form results in increased abundance of Calcium Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]; Calcium affects the reaction [CALM1 protein modified form binds to and affects the activity of RYR1 protein] |
CTD |
PMID:15381065 PMID:15628869 PMID:16372898 PMID:17707769 PMID:18719443 PMID:18954145 PMID:19191329 PMID:21485675 More...
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NCBI chr19:38,433,691...38,587,564
Ensembl chr19:38,433,691...38,595,273
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G |
RYR2 |
ryanodine receptor 2 |
multiple interactions |
EXP ISO |
FKBP1A protein inhibits the reaction [Calcium results in increased activity of RYR2 protein] Dantrolene inhibits the reaction [Caffeine promotes the reaction [RYR2 protein results in increased secretion of Calcium]]; HOMER1 protein alternative form inhibits the reaction [Caffeine promotes the reaction [RYR2 protein results in increased secretion of Calcium]]; HOMER1 protein alternative form inhibits the reaction [Cyclic ADP-Ribose promotes the reaction [RYR2 protein results in increased secretion of Calcium]] |
CTD |
PMID:12887973 PMID:17872463 |
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NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988
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G |
S100A13 |
S100 calcium binding protein A13 |
multiple interactions |
EXP |
[Calcium co-treated with Copper] binds to and affects the folding of S100A13 protein; Calcium binds to and affects the folding of S100A13 protein |
CTD |
PMID:16766622 |
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NCBI chr 1:153,618,799...153,634,361
Ensembl chr 1:153,618,787...153,631,360
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G |
S100A2 |
S100 calcium binding protein A2 |
affects binding multiple interactions |
EXP |
Calcium binds to S100A2 protein [Zinc binds to S100A2 protein] inhibits the reaction [Calcium binds to S100A2 protein] |
CTD |
PMID:17239974 |
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NCBI chr 1:153,561,108...153,565,844
Ensembl chr 1:153,561,108...153,567,890
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G |
S100A6 |
S100 calcium binding protein A6 |
affects response to substance |
EXP |
S100A6 protein affects the susceptibility to Calcium |
CTD |
PMID:15068510 |
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NCBI chr 1:153,534,599...153,535,991
Ensembl chr 1:153,534,599...153,536,244
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G |
S100A8 |
S100 calcium binding protein A8 |
multiple interactions affects binding |
EXP |
[Zinc co-treated with Calcium] binds to [S100A8 protein binds to S100A9 protein] Calcium binds to [S100A8 protein binds to S100A9 protein] |
CTD |
PMID:17050004 |
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NCBI chr 1:153,390,032...153,422,583
Ensembl chr 1:153,390,032...153,391,073
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G |
S100A9 |
S100 calcium binding protein A9 |
affects binding multiple interactions |
EXP |
Calcium binds to [S100A8 protein binds to S100A9 protein] [Zinc co-treated with Calcium] binds to [S100A8 protein binds to S100A9 protein] |
CTD |
PMID:17050004 |
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NCBI chr 1:153,357,854...153,361,023
Ensembl chr 1:153,357,854...153,361,023
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G |
S100G |
S100 calcium binding protein G |
affects expression |
ISO |
Calcium affects the expression of S100G mRNA |
CTD |
PMID:15913539 |
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NCBI chr X:16,650,158...16,654,670
Ensembl chr X:16,650,158...16,654,670
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G |
SCGB1A1 |
secretoglobin family 1A member 1 |
increases expression |
EXP |
Calcium results in increased expression of SCGB1A1 mRNA; Calcium results in increased expression of SCGB1A1 protein |
CTD |
PMID:16237193 |
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NCBI chr11:62,419,033...62,423,195
Ensembl chr11:62,405,103...62,423,195
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G |
SCT |
secretin |
increases abundance |
EXP |
SCT protein results in increased abundance of Calcium |
CTD |
PMID:1220513 |
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NCBI chr11:626,309...627,181
Ensembl chr11:626,309...627,181
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G |
SEC61A1 |
SEC61 translocon subunit alpha 1 |
multiple interactions increases transport |
EXP |
[HSPA5 protein binds to SEC61A1 protein] which results in decreased transport of Calcium; [SEC61A1 protein results in increased transport of Calcium] which results in increased susceptibility to Thapsigargin; DNAJB11 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium]; DNAJC3 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium] |
CTD |
PMID:26085089 |
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NCBI chr 3:128,051,641...128,071,683
Ensembl chr 3:128,051,641...128,071,705
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G |
SELENOT |
selenoprotein T |
multiple interactions affects abundance |
ISO |
Calcium affects the reaction [ADCYAP1 protein results in increased expression of SELENOT mRNA]; SELENOT protein affects the reaction [ADCYAP1 protein results in increased abundance of Calcium]; Thapsigargin promotes the reaction [SELENOT protein affects the abundance of Calcium] |
CTD |
PMID:18198219 |
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NCBI chr 3:150,603,321...150,630,436
Ensembl chr 3:150,602,875...150,630,436
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G |
SERPINE1 |
serpin family E member 1 |
increases stability |
EXP |
Calcium results in increased stability of SERPINE1 protein |
CTD |
PMID:21280127 PMID:21280128 |
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NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
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G |
SLC12A5 |
solute carrier family 12 member 5 |
multiple interactions |
ISO |
Calcium affects the reaction [Zinc results in increased activity of SLC12A5 protein] |
CTD |
PMID:22441041 |
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NCBI chr20:46,021,686...46,060,150
Ensembl chr20:46,021,690...46,060,150
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G |
SLC23A2 |
solute carrier family 23 member 2 |
decreases expression multiple interactions increases expression |
ISO |
Calcium deficiency results in decreased expression of SLC23A2 mRNA Foscarnet inhibits the reaction [Calcium results in increased expression of SLC23A2 mRNA]; Nifedipine inhibits the reaction [Calcium results in increased expression of SLC23A2 mRNA] Calcium results in increased expression of SLC23A2 mRNA; Calcium results in increased expression of SLC23A2 protein |
CTD |
PMID:12788230 |
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NCBI chr20:4,852,358...5,010,313
Ensembl chr20:4,852,356...5,010,293
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G |
SLC24A2 |
solute carrier family 24 member 2 |
increases uptake |
ISO |
SLC24A2 protein results in increased uptake of Calcium |
CTD |
PMID:14660663 |
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NCBI chr 9:19,507,455...20,307,892
Ensembl chr 9:19,507,452...19,789,037
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G |
SLC2A1 |
solute carrier family 2 member 1 |
multiple interactions |
ISO |
Calcium deficiency inhibits the reaction [2,3-dinitrophenol results in increased activity of SLC2A1 protein]; Calcium deficiency inhibits the reaction [Arsenates results in increased activity of SLC2A1 protein]; Calcium deficiency inhibits the reaction [Azides results in increased activity of SLC2A1 protein]; Calcium deficiency inhibits the reaction [INS1 protein results in increased activity of SLC2A1 protein] |
CTD |
PMID:10970766 |
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NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893
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G |
SLC2A2 |
solute carrier family 2 member 2 |
multiple interactions |
ISO |
[CACNA1D protein results in increased uptake of Calcium] which affects the localization of SLC2A2 protein |
CTD |
PMID:17272349 |
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NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743
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G |
SLC2A4 |
solute carrier family 2 member 4 |
multiple interactions |
ISO |
[[Chloroquine results in increased abundance of Calcium] which affects the localization of SLC2A4 protein] which results in increased uptake of Glucose; [Chloroquine results in increased abundance of Calcium] which affects the localization of SLC2A4 protein |
CTD |
PMID:27160165 |
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NCBI chr17:7,281,718...7,288,257
Ensembl chr17:7,281,718...7,288,257
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G |
SLC30A1 |
solute carrier family 30 member 1 |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of SLC30A1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 1:211,571,568...211,579,161
Ensembl chr 1:211,571,568...211,579,161
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G |
SLC5A1 |
solute carrier family 5 member 1 |
multiple interactions |
ISO |
SLC5A1 protein affects the reaction [CACNA1D protein results in increased uptake of Calcium] |
CTD |
PMID:17272349 |
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NCBI chr22:32,043,261...32,113,029
Ensembl chr22:32,043,261...32,113,029
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G |
SLC8A1 |
solute carrier family 8 member A1 |
multiple interactions increases transport |
EXP ISO |
Calcium inhibits the reaction [SLC8A1 protein results in increased uptake of Nickel] SLC8A1 protein results in increased transport of Calcium 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [SLC8A1 protein results in increased transport of Calcium] PPP3R1 gene mutant form inhibits the reaction [SLC8A1 protein affects the transport of Calcium] |
CTD |
PMID:10329968 PMID:18822394 PMID:19700627 |
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NCBI chr 2:40,097,270...40,512,435
Ensembl chr 2:40,097,270...40,611,053
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G |
SLC8A2 |
solute carrier family 8 member A2 |
increases uptake |
ISO |
SLC8A2 protein results in increased uptake of Calcium |
CTD |
PMID:14660663 |
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NCBI chr19:47,428,017...47,471,893
Ensembl chr19:47,428,017...47,471,893
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G |
SLC8A3 |
solute carrier family 8 member A3 |
increases transport increases uptake |
ISO |
SLC8A3 protein results in increased transport of Calcium SLC8A3 protein results in increased uptake of Calcium |
CTD |
PMID:14660663 PMID:17585341 PMID:29434186 |
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NCBI chr14:70,044,215...70,189,405
Ensembl chr14:70,044,215...70,189,480
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G |
SLC9A1 |
solute carrier family 9 member A1 |
multiple interactions |
ISO |
3-methylsulfonyl-4-piperidinobenzoyl guanidine inhibits the reaction [[Phenylephrine results in increased activity of SLC9A1 protein] which results in increased transport of Calcium]; [[Phenylephrine results in increased activity of SLC9A1 protein] which results in increased transport of Calcium] which results in increased expression of ATP2A2 protein; [Phenylephrine results in increased activity of SLC9A1 protein] which results in increased transport of Calcium |
CTD |
PMID:16236312 |
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NCBI chr 1:27,098,809...27,155,125
Ensembl chr 1:27,098,809...27,166,981
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G |
SNCA |
synuclein alpha |
multiple interactions increases uptake |
ISO |
omega-Conotoxin GVIA inhibits the reaction [SNCA protein results in increased uptake of Calcium] |
CTD |
PMID:17179863 |
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NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315
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G |
SOD1 |
superoxide dismutase 1 |
multiple interactions increases transport |
EXP ISO |
SOD1 protein mutant form promotes the reaction [SOD1 protein binds to Calcium] SOD1 protein modified form results in increased transport of Calcium; SOD1 protein results in increased transport of Calcium [Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in decreased activity of SOD1 protein]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in decreased activity of SOD1 protein]; [Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of SOD1 protein]; Calcium affects the reaction [sodium arsenite results in decreased activity of SOD1 protein] |
CTD |
PMID:19227972 PMID:22534743 PMID:24184500 PMID:28085149 |
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NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
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G |
SOD2 |
superoxide dismutase 2 |
multiple interactions |
ISO |
[Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in decreased activity of SOD2 protein]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in decreased activity of SOD2 protein]; [Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of SOD2 protein]; Calcium affects the reaction [sodium arsenite results in decreased activity of SOD2 protein] |
CTD |
PMID:22534743 PMID:24184500 |
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NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
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G |
SP7 |
Sp7 transcription factor |
affects secretion |
ISO |
SP7 protein affects the secretion of Calcium |
CTD |
PMID:19064586 |
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NCBI chr12:53,326,575...53,344,793
Ensembl chr12:53,326,575...53,345,315
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G |
SPHK1 |
sphingosine kinase 1 |
multiple interactions |
EXP ISO |
[C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium; resveratrol inhibits the reaction [[C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium] |
CTD |
PMID:19284563 PMID:19346296 |
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NCBI chr17:76,383,204...76,387,855
Ensembl chr17:76,376,584...76,387,860
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G |
SPP1 |
secreted phosphoprotein 1 |
increases expression affects expression multiple interactions |
ISO |
Calcium results in increased expression of SPP1 mRNA Calcium affects the expression of SPP1 mRNA Foscarnet inhibits the reaction [Calcium results in increased expression of SPP1 mRNA]; Nifedipine inhibits the reaction [Calcium results in increased expression of SPP1 mRNA] |
CTD |
PMID:12788230 PMID:15913539 |
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NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
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G |
SPP2 |
secreted phosphoprotein 2 |
affects expression |
ISO |
Calcium affects the expression of SPP2 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 2:234,050,702...234,077,134
Ensembl chr 2:234,050,679...234,077,134
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G |
SPTAN1 |
spectrin alpha, non-erythrocytic 1 |
multiple interactions increases cleavage |
ISO |
((1S)-1-((((1S)-1-benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester inhibits the reaction [Calcium results in increased cleavage of SPTAN1 protein]; Edetic Acid inhibits the reaction [Calcium results in increased cleavage of SPTAN1 protein]; N-(4-fluorophenylsulfonyl)-L-valyl-L-leucinal inhibits the reaction [Calcium results in increased cleavage of SPTAN1 protein] |
CTD |
PMID:17069801 |
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NCBI chr 9:128,552,587...128,633,662
Ensembl chr 9:128,552,558...128,633,662
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G |
SQSTM1 |
sequestosome 1 |
affects expression |
ISO |
Calcium affects the expression of SQSTM1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
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G |
SRC |
SRC proto-oncogene, non-receptor tyrosine kinase |
affects transport multiple interactions affects response to substance |
ISO |
SRC protein affects the transport of Calcium Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of SRC protein] SRC protein affects the susceptibility to Calcium |
CTD |
PMID:17551092 PMID:19782052 |
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NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050
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G |
STAR |
steroidogenic acute regulatory protein |
multiple interactions |
ISO |
Calcium inhibits the reaction [Cyclic AMP results in increased expression of STAR protein] |
CTD |
PMID:19822634 |
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NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
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G |
STAT1 |
signal transducer and activator of transcription 1 |
multiple interactions |
EXP |
Calcium promotes the reaction [[Diclofenac co-treated with IFNG protein] results in increased phosphorylation of STAT1 protein] |
CTD |
PMID:26609140 |
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NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960
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G |
STIM1 |
stromal interaction molecule 1 |
affects abundance increases uptake multiple interactions |
EXP ISO |
STIM1 protein affects the abundance of Calcium STIM1 protein results in increased uptake of Calcium [Calcium affects the activity of and affects the localization of STIM1 protein] which affects the activity of ORAI1 protein; STIM1 protein promotes the reaction [Taurodeoxycholic Acid results in increased abundance of Calcium] |
CTD |
PMID:18342630 PMID:18439569 PMID:23212906 PMID:24990931 |
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NCBI chr11:3,854,604...4,093,210
Ensembl chr11:3,854,527...4,093,210
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G |
STMN1 |
stathmin 1 |
affects expression |
ISO |
Calcium affects the expression of STMN1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 1:25,884,179...25,906,880
Ensembl chr 1:25,884,181...25,906,991
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G |
SUGT1 |
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone |
multiple interactions |
EXP |
Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to SUGT1 protein]] |
CTD |
PMID:23184943 |
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NCBI chr13:52,652,836...52,700,909
Ensembl chr13:52,652,709...52,700,909
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G |
SYN2 |
synapsin II |
multiple interactions decreases abundance |
ISO |
SYN2 mutant form inhibits the reaction [Adenosine Triphosphate results in increased abundance of Calcium] SYN2 mutant form results in decreased abundance of Calcium |
CTD |
PMID:18701217 |
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NCBI chr 3:12,004,388...12,192,032
Ensembl chr 3:12,004,388...12,192,032
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G |
SYT1 |
synaptotagmin 1 |
affects binding |
ISO |
Calcium binds to SYT1 protein |
CTD |
PMID:16262243 |
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NCBI chr12:78,863,982...79,452,008
Ensembl chr12:78,863,993...79,452,008
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G |
TAC1 |
tachykinin precursor 1 |
increases transport |
ISO |
TAC1 protein modified form results in increased transport of Calcium |
CTD |
PMID:30116771 |
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NCBI chr 7:97,732,086...97,740,472
Ensembl chr 7:97,732,084...97,740,472
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G |
TAOK1 |
TAO kinase 1 |
affects expression |
ISO |
Calcium affects the expression of TAOK1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr17:29,390,363...29,551,903
Ensembl chr17:29,390,363...29,551,903
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G |
TBXA2R |
thromboxane A2 receptor |
multiple interactions increases transport |
EXP |
rosiglitazone inhibits the reaction [TBXA2R protein results in increased transport of Calcium]; troglitazone inhibits the reaction [TBXA2R protein results in increased transport of Calcium] |
CTD |
PMID:16499875 |
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NCBI chr19:3,594,507...3,606,875
Ensembl chr19:3,594,507...3,606,875
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G |
TGFA |
transforming growth factor alpha |
increases abundance |
EXP |
TGFA protein results in increased abundance of Calcium |
CTD |
PMID:11527950 |
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NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193
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G |
TGFB1 |
transforming growth factor beta 1 |
increases abundance increases uptake |
EXP ISO |
TGFB1 protein results in increased abundance of Calcium TGFB1 protein results in increased uptake of Calcium |
CTD |
PMID:15703175 PMID:17090780 |
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NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
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G |
TGM1 |
transglutaminase 1 |
increases expression multiple interactions |
EXP |
Calcium results in increased expression of TGM1 mRNA NPS R-467 promotes the reaction [Calcium results in increased expression of TGM1 mRNA] |
CTD |
PMID:10469331 |
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NCBI chr14:24,249,114...24,263,177
Ensembl chr14:24,249,114...24,264,432
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G |
TIMM17A |
translocase of inner mitochondrial membrane 17A |
affects expression |
ISO |
Calcium affects the expression of TIMM17A mRNA |
CTD |
PMID:15913539 |
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NCBI chr 1:201,955,503...201,970,664
Ensembl chr 1:201,955,503...201,970,664
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G |
TJP1 |
tight junction protein 1 |
multiple interactions |
EXP |
Calcium deficiency inhibits the reaction [TJP1 protein binds to OCLN protein] |
CTD |
PMID:11054866 |
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NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915
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G |
TNF |
tumor necrosis factor |
multiple interactions |
ISO EXP |
KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]] [IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]; [TNF protein co-treated with IFNG protein] promotes the reaction [Diclofenac affects the abundance of Calcium]; Calcium affects the reaction [Morphine inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]] |
CTD |
PMID:23747339 PMID:24068670 PMID:26609140 |
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NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
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G |
TNFAIP6 |
TNF alpha induced protein 6 |
multiple interactions |
EXP |
Calcium promotes the reaction [ITIH1 protein binds to TNFAIP6 protein]; Calcium promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] |
CTD |
PMID:16768462 |
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NCBI chr 2:151,357,592...151,381,340
Ensembl chr 2:151,357,592...151,380,046
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G |
TNFRSF11B |
TNF receptor superfamily member 11b |
multiple interactions |
ISO |
TNFRSF11B protein inhibits the reaction [IL11 protein results in increased abundance of Calcium]; TNFRSF11B protein inhibits the reaction [TNFSF11 protein results in increased abundance of Calcium] |
CTD |
PMID:12110441 |
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NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885
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G |
TNFSF11 |
TNF superfamily member 11 |
multiple interactions increases abundance |
ISO |
TNFRSF11B protein inhibits the reaction [TNFSF11 protein results in increased abundance of Calcium] |
CTD |
PMID:12110441 |
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NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013
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G |
TNNC1 |
troponin C1, slow skeletal and cardiac type |
affects binding |
EXP |
TNNC1 protein binds to Calcium |
CTD |
PMID:18212018 |
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NCBI chr 3:52,451,100...52,454,041
Ensembl chr 3:52,451,100...52,454,041
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G |
TP53 |
tumor protein p53 |
decreases expression affects localization |
EXP |
Calcium results in decreased expression of TP53 protein TP53 protein affects the localization of Calcium |
CTD |
PMID:15059885 PMID:16043423 |
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NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
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G |
TP73 |
tumor protein p73 |
multiple interactions |
EXP |
[Calcium co-treated with CAPN1 protein] results in increased degradation of TP73 protein modified form |
CTD |
PMID:21516125 |
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NCBI chr 1:3,652,516...3,736,201
Ensembl chr 1:3,652,516...3,736,201
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G |
TRPA1 |
transient receptor potential cation channel subfamily A member 1 |
affects activity multiple interactions |
ISO EXP |
Calcium affects the activity of TRPA1 protein [allicin binds to and results in increased activity of TRPA1 protein] which results in increased transport of Calcium; [allyl isothiocyanate binds to and results in increased activity of TRPA1 protein] which results in increased transport of Calcium; [cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester co-treated with TRPA1 protein] results in increased uptake of Calcium; Calcium affects the reaction [Capsaicin inhibits the reaction [TRPA1 protein affects the susceptibility to mustard oil]]; TRPA1 affects the reaction [AM 1241 results in increased abundance of Calcium]; TRPA1 promotes the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased abundance of Calcium]; TRPA1 promotes the reaction [mustard oil results in increased abundance of Calcium] 4-(4-chlorophenyl)-3-methylbut-3-en-2-oxime inhibits the reaction [[2-chloroethyl ethyl sulfide results in increased activity of TRPA1 protein] which results in increased uptake of Calcium]; 4-(4-chlorophenyl)-3-methylbut-3-en-2-oxime inhibits the reaction [[Mustard Gas results in increased activity of TRPA1 protein] which results in increased uptake of Calcium]; [2-chloroethyl ethyl sulfide results in increased activity of TRPA1 protein] which results in increased uptake of Calcium; [allyl isothiocyanate results in increased activity of TRPA1 protein] which results in increased uptake of Calcium; [cannabidivarin results in increased activity of TRPA1 protein] which results in increased uptake of Calcium; [Cannabinol results in increased activity of TRPA1 protein] which results in increased uptake of Calcium; [cinnamaldehyde results in increased activity of TRPA1 protein] which results in increased transport of Calcium; [cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester co-treated with TRPA1 protein] results in increased uptake of Calcium; [hydroquinone results in increased activity of TRPA1 protein] which results in increased import of Calcium; [Mustard Gas results in increased activity of TRPA1 protein] which results in increased uptake of Calcium; [Pyruvaldehyde results in increased activity of TRPA1 protein] which results in increased transport of Calcium; [Vehicle Emissions results in increased activity of TRPA1 protein] which results in increased import of Calcium; Acetylcysteine inhibits the reaction [[allyl isothiocyanate results in increased activity of TRPA1 protein] which results in increased uptake of Calcium]; Acetylcysteine inhibits the reaction [[Mustard Gas results in increased activity of TRPA1 protein] which results in increased uptake of Calcium]; Dithiothreitol inhibits the reaction [[hydroquinone results in increased activity of TRPA1 protein] which results in increased import of Calcium]; mustard oil promotes the reaction [[hydroquinone results in increased activity of TRPA1 protein] which results in increased import of Calcium]; TRPA1 mRNA affects the reaction [Acrolein results in increased uptake of Calcium]; TRPA1 mRNA affects the reaction [allyl isothiocyanate results in increased uptake of Calcium]; TRPA1 mRNA affects the reaction [cinnamaldehyde results in increased uptake of Calcium] |
CTD |
PMID:15843607 PMID:17314320 PMID:17590514 PMID:18234885 PMID:19507004 PMID:20086034 PMID:22863862 PMID:27738742 PMID:28790335 PMID:30945539 PMID:31096838 More...
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NCBI chr 8:72,021,250...72,090,010
Ensembl chr 8:72,019,917...72,075,584
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G |
TRPC1 |
transient receptor potential cation channel subfamily C member 1 |
increases uptake increases import increases transport decreases transport multiple interactions |
ISO EXP |
TRPC1 protein results in increased uptake of Calcium TRPC1 protein results in increased import of Calcium TRPC1 protein results in increased transport of Calcium TRPC1 protein results in decreased transport of Calcium LEP protein promotes the reaction [TRPC1 protein results in increased transport of Calcium] |
CTD |
PMID:17174323 PMID:18822394 PMID:20107083 PMID:22157757 PMID:24953315 |
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NCBI chr 3:142,724,034...142,807,888
Ensembl chr 3:142,724,034...142,807,888
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G |
TRPC3 |
transient receptor potential cation channel subfamily C member 3 |
multiple interactions increases transport affects transport affects secretion |
EXP ISO |
1-oleoyl-2-acetylglycerol affects the reaction [TRPC3 protein affects the transport of Calcium]; 1-oleoyl-2-acetylglycerol promotes the reaction [TRPC3 protein results in increased transport of Calcium]; OXT protein promotes the reaction [TRPC3 protein results in increased transport of Calcium]; Thapsigargin promotes the reaction [TRPC3 protein results in increased transport of Calcium] TRPC3 protein affects the secretion of Calcium 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [[Phenylephrine results in increased expression of TRPC3 protein] which results in increased transport of Calcium]; [Phenylephrine results in increased expression of TRPC3 protein] which results in increased transport of Calcium; TRPC3 protein promotes the reaction [1-oleoyl-2-acetoyl-sn-glycerol results in increased transport of Calcium]; TRPC3 protein promotes the reaction [Phenylephrine results in increased transport of Calcium]; TRPC3 protein promotes the reaction [Thapsigargin results in increased transport of Calcium] |
CTD |
PMID:12700192 PMID:12736256 PMID:15672411 PMID:16484216 PMID:17351372 PMID:18822394 PMID:19244478 More...
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NCBI chr 4:121,874,481...121,952,060
Ensembl chr 4:121,874,481...121,952,060
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G |
TRPC4 |
transient receptor potential cation channel subfamily C member 4 |
multiple interactions increases transport |
EXP ISO |
TRPC4 protein affects the reaction [Arachidonic Acid results in increased transport of Calcium]; TRPC4 protein affects the reaction [Carbachol results in increased transport of Calcium] TRPC4 protein results in increased transport of Calcium LEP protein promotes the reaction [TRPC4 protein results in increased transport of Calcium] |
CTD |
PMID:11830588 PMID:20107083 |
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NCBI chr13:37,632,063...37,869,772
Ensembl chr13:37,632,063...37,869,802
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G |
TRPC5 |
transient receptor potential cation channel subfamily C member 5 |
multiple interactions increases transport affects transport |
EXP ISO |
1-oleoyl-2-acetylglycerol affects the reaction [TRPC5 protein affects the transport of Calcium]; 2-aminoethoxydiphenyl borate promotes the reaction [resveratrol inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]]; Ascorbic Acid inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; Calcium promotes the reaction [resveratrol inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]]; Carbachol promotes the reaction [TRPC5 protein results in increased transport of Calcium]; CAT protein inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; CAT protein inhibits the reaction [Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; Diethylstilbestrol inhibits the reaction [TRPC5 protein results in increased transport of Calcium]; Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]; Gallic Acid inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; Gallic Acid inhibits the reaction [Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]; Lysophosphatidylcholines promotes the reaction [TRPC5 protein results in increased transport of Calcium]; resveratrol inhibits the reaction [Carbachol promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; resveratrol inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; resveratrol inhibits the reaction [Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; resveratrol inhibits the reaction [Lysophosphatidylcholines promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; resveratrol inhibits the reaction [TRPC5 protein results in increased transport of Calcium]; resveratrol promotes the reaction [Ascorbic Acid inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]] LEP protein promotes the reaction [TRPC5 protein results in increased transport of Calcium] |
CTD |
PMID:17351372 PMID:20107083 PMID:21127073 |
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NCBI chr X:111,768,011...112,082,776
Ensembl chr X:111,768,011...112,082,776
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G |
TRPC6 |
transient receptor potential cation channel subfamily C member 6 |
affects transport increases uptake multiple interactions increases transport |
EXP ISO |
TRPC6 protein affects the transport of Calcium TRPC6 protein results in increased uptake of Calcium 1,2-dioctanoylglycerol promotes the reaction [TRPC6 protein results in increased uptake of Calcium]; 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [1-oleoyl-2-acetoyl-sn-glycerol promotes the reaction [TRPC6 protein results in increased uptake of Calcium]]; 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [Acetylcholine promotes the reaction [TRPC6 protein results in increased uptake of Calcium]]; 1-oleoyl-2-acetoyl-sn-glycerol promotes the reaction [Acetylcholine promotes the reaction [TRPC6 protein results in increased uptake of Calcium]]; 1-oleoyl-2-acetoyl-sn-glycerol promotes the reaction [TRPC6 protein results in increased uptake of Calcium]; 2-aminoethyl diphenylborinate inhibits the reaction [Acetylcholine promotes the reaction [TRPC6 protein results in increased uptake of Calcium]]; 2-aminoethyl diphenylborinate inhibits the reaction [Thapsigargin promotes the reaction [TRPC6 protein results in increased uptake of Calcium]]; Acetylcholine promotes the reaction [TRPC6 protein results in increased uptake of Calcium]; Flufenamic Acid inhibits the reaction [1-oleoyl-2-acetoyl-sn-glycerol promotes the reaction [TRPC6 protein results in increased uptake of Calcium]]; Thapsigargin promotes the reaction [TRPC6 protein results in increased uptake of Calcium]; TRPC6 protein promotes the reaction [1-oleoyl-2-acetoyl-sn-glycerol results in increased transport of Calcium]; TRPC6 protein promotes the reaction [Phenylephrine results in increased transport of Calcium] [Diglycerides results in increased activity of TRPC6 protein] which results in increased abundance of Calcium; [Flufenamic Acid results in increased activity of TRPC6 protein] which results in increased uptake of Calcium; CASR protein promotes the reaction [TRPC6 protein results in increased uptake of Calcium]; TRPC6 protein promotes the reaction [[VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium]; VEGFA protein promotes the reaction [[Diglycerides results in increased activity of TRPC6 protein] which results in increased abundance of Calcium] TRPC6 protein results in increased transport of Calcium |
CTD |
PMID:11179201 PMID:11535132 PMID:14551041 PMID:15672411 PMID:18209485 PMID:18822394 PMID:21562303 More...
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NCBI chr11:101,451,564...101,584,007
Ensembl chr11:101,451,564...101,872,562
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G |
TRPM2 |
transient receptor potential cation channel subfamily M member 2 |
increases transport multiple interactions |
EXP ISO |
TRPM2 protein results in increased transport of Calcium TRPM2 protein promotes the reaction [Adenosine Diphosphate Ribose results in increased uptake of Calcium]; TRPM2 protein promotes the reaction [Hydrogen Peroxide results in increased uptake of Calcium] [Clotrimazole results in decreased activity of TRPM2 protein] inhibits the reaction [Mustard Gas results in increased abundance of Calcium]; [Econazole results in decreased activity of TRPM2 protein] inhibits the reaction [Mustard Gas results in increased abundance of Calcium]; TRPM2 protein affects the reaction [Mustard Gas results in increased abundance of Calcium] Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]; Calcium affects the reaction [Hydrogen Peroxide promotes the reaction [TRPM2 protein results in increased transport of Calcium]]; Clotrimazole inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]]; Flufenamic Acid inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]]; Hydrogen Peroxide promotes the reaction [TRPM2 protein results in increased transport of Calcium] |
CTD |
PMID:12529379 PMID:20878536 PMID:21900507 PMID:22036725 |
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NCBI chr21:44,353,621...44,442,644
Ensembl chr21:44,350,163...44,443,081
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G |
TRPM4 |
transient receptor potential cation channel subfamily M member 4 |
multiple interactions increases activity |
ISO EXP |
Calcium binds to and results in increased activity of TRPM4 protein [Ionomycin co-treated with Calcium co-treated with CAMK2D protein] results in increased activity of TRPM4 protein Calcium results in increased activity of TRPM4 protein |
CTD |
PMID:16966582 PMID:17188667 PMID:33392831 |
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NCBI chr19:49,157,792...49,211,836
Ensembl chr19:49,157,741...49,211,836
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G |
TRPM6 |
transient receptor potential cation channel subfamily M member 6 |
multiple interactions |
EXP |
Gadolinium inhibits the reaction [TRPM6 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Calcium]]; Lanthanum inhibits the reaction [TRPM6 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Calcium]]; TRPM6 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Calcium]; TRPM6 protein affects the reaction [1-stearoyl-2-arachidonoylglycerol results in increased transport of Calcium] |
CTD |
PMID:11988098 |
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NCBI chr 9:74,722,495...74,887,921
Ensembl chr 9:74,722,495...74,888,094
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G |
TRPM7 |
transient receptor potential cation channel subfamily M member 7 |
increases abundance decreases abundance multiple interactions |
EXP ISO |
TRPM7 protein results in increased abundance of Calcium TRPM7 gene mutant form results in decreased abundance of Calcium Magnesium inhibits the reaction [TRPM7 protein results in increased abundance of Calcium] |
CTD |
PMID:19515901 PMID:30770447 |
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NCBI chr15:50,557,158...50,686,797
Ensembl chr15:50,552,473...50,686,797
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G |
TRPM8 |
transient receptor potential cation channel subfamily M member 8 |
affects transport multiple interactions increases transport |
ISO EXP |
TRPM8 protein affects the transport of Calcium [icilin binds to and results in increased activity of TRPM8 protein] which affects the abundance of Calcium; [Menthol binds to and results in increased activity of TRPM8 protein] which affects the abundance of Calcium TRPM8 protein results in increased transport of Calcium [icilin results in increased activity of TRPM8 protein] which results in increased transport of Calcium; [Menthol analog binds to and results in increased activity of TRPM8 protein] which results in increased transport of Calcium; [Menthol results in increased activity of TRPM8 protein] which results in increased transport of Calcium; Calcium deficiency inhibits the reaction [Praziquantel results in increased activity of TRPM8 protein]; icilin promotes the reaction [TRPM8 protein results in increased transport of Calcium]; Menthol promotes the reaction [TRPM8 protein results in increased transport of Calcium] |
CTD |
PMID:16174775 PMID:17517434 PMID:18485891 PMID:18524940 PMID:19363131 PMID:23296101 PMID:29054683 More...
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NCBI chr 2:233,917,373...234,019,522
Ensembl chr 2:233,917,373...234,019,522
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G |
TRPV1 |
transient receptor potential cation channel subfamily V member 1 |
affects import multiple interactions increases import |
EXP ISO |
TRPV1 protein affects the import of Calcium 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [anandamide promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [arachidonyl dopamine promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [N-oleoyldopamine promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; [Capsaicin results in increased activity of TRPV1 protein] which results in increased transport of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin results in increased activity of TRPV1] which results in increased uptake of Calcium; [Formaldehyde results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium; Amitriptyline inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Butyrates promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Cadmium inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Calcium affects the reaction [Capsaicin inhibits the reaction [TRPV1 protein affects the susceptibility to Capsaicin]]; Calcium affects the reaction [mustard oil inhibits the reaction [TRPV1 protein affects the susceptibility to Capsaicin]]; capsazepine inhibits the reaction [[Formaldehyde results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]; capsazepine inhibits the reaction [[Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; Cobalt inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Copper inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; HTR2A protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; HTR7 protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; Indomethacin inhibits the reaction [[Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; Lidocaine promotes the reaction [TRPV1 protein results in increased abundance of Calcium]; Masoprocol inhibits the reaction [[Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; Nickel inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Ruthenium Red inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Serotonin promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased transport of Calcium] 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [anandamide promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [arachidonyl dopamine promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [N-oleoyldopamine promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [Protons promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; [arachidonyl dopamine results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [cannabichromene results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [Cannabidiol results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [cannabidiolic acid results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [cannabidivarin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [cannabigerol results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [cannabigerolic acid results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin binds to and results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [Capsaicin binds to TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased import of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin results in increased activity of TRPV1] which results in increased uptake of Calcium; [N-oleoyldopamine results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [nonivamide binds to and results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [resiniferatoxin binds to and results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [resiniferatoxin binds to TRPV1 protein] which results in increased uptake of Calcium; Cannabidiol inhibits the reaction [[Capsaicin binds to TRPV1 protein] which results in increased uptake of Calcium]; Cannabidiol inhibits the reaction [[resiniferatoxin binds to TRPV1 protein] which results in increased uptake of Calcium]; Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]; Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]; capsazepine inhibits the reaction [[Cannabidiol results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; capsazepine inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]]; capsazepine inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; capsazepine inhibits the reaction [Sodium affects the reaction [TRPV1 protein results in increased abundance of Calcium]]; Edetic Acid inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]; iodoresiniferatoxin inhibits the reaction [[N-oleoyldopamine results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; iodoresiniferatoxin inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]]; iodoresiniferatoxin inhibits the reaction [Sodium affects the reaction [TRPV1 protein results in increased abundance of Calcium]]; PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]]; Ruthenium Red inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]]; Ruthenium Red inhibits the reaction [Sodium affects the reaction [TRPV1 protein results in increased abundance of Calcium]]; Sodium affects the reaction [TRPV1 protein results in increased abundance of Calcium]; TRPV1 promotes the reaction [Capsaicin results in increased uptake of Calcium] Sodium affects the reaction [TRPV1 protein results in increased abundance of Calcium]; TRPV1 protein affects the reaction [Capsaicin results in increased abundance of Calcium]; TRPV1 protein affects the reaction [Capsaicin results in increased transport of Calcium] TRPV1 protein results in increased import of Calcium |
CTD |
PMID:11606325 PMID:12569099 PMID:12886029 PMID:15471852 PMID:15615864 PMID:16597917 PMID:16793902 PMID:16901936 PMID:17332266 PMID:17442041 PMID:17508023 PMID:17590514 PMID:17881535 PMID:18172555 PMID:18230619 PMID:18249134 PMID:18331834 PMID:19602228 PMID:19847360 PMID:21453681 PMID:23264033 PMID:28790335 PMID:31096838 More...
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NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411
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G |
TRPV2 |
transient receptor potential cation channel subfamily V member 2 |
multiple interactions |
EXP |
[cannabichromene results in increased activity of TRPV2 protein] which results in increased uptake of Calcium; [Cannabidiol results in increased activity of TRPV2 protein] which results in increased uptake of Calcium; [cannabidiolic acid results in increased activity of TRPV2 protein] which results in increased uptake of Calcium; [cannabidivarin results in increased activity of TRPV2 protein] which results in increased uptake of Calcium |
CTD |
PMID:31096838 |
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NCBI chr17:16,415,571...16,437,003
Ensembl chr17:16,415,571...16,437,003
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TRPV3 |
transient receptor potential cation channel subfamily V member 3 |
multiple interactions |
ISO |
[carvacrol binds to and results in increased activity of TRPV3 protein] which results in increased transport of Calcium; [carvacrol results in increased activity of TRPV3 protein] which results in increased transport of Calcium; [Eugenol binds to and results in increased activity of TRPV3 protein] which results in increased transport of Calcium; Ruthenium Red inhibits the reaction [[carvacrol binds to and results in increased activity of TRPV3 protein] which results in increased transport of Calcium] [carvacrol results in increased activity of TRPV3 protein] which results in increased transport of Calcium; [Eugenol results in increased activity of TRPV3 protein] which results in increased transport of Calcium |
CTD |
PMID:16617338 PMID:20086034 |
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NCBI chr17:3,510,502...3,557,812
Ensembl chr17:3,510,502...3,557,812
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G |
TRPV4 |
transient receptor potential cation channel subfamily V member 4 |
multiple interactions |
EXP ISO |
TRPV4 protein promotes the reaction [phorbol-12,13-didecanoate results in increased import of Calcium] TRPV4 protein promotes the reaction [ITGA2 protein promotes the reaction [[Dinoprostone co-treated with Serotonin] results in increased import of Calcium]] |
CTD |
PMID:18234883 PMID:18355916 |
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NCBI chr12:109,783,087...109,833,398
Ensembl chr12:109,783,087...109,833,406
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TRPV5 |
transient receptor potential cation channel subfamily V member 5 |
increases uptake multiple interactions |
EXP ISO |
TRPV5 protein results in increased uptake of Calcium KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]] |
CTD |
PMID:23747339 |
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NCBI chr 7:142,908,101...142,933,746
Ensembl chr 7:142,908,101...142,933,746
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G |
TRPV6 |
transient receptor potential cation channel subfamily V member 6 |
increases transport multiple interactions increases uptake increases expression |
EXP ISO |
TRPV6 protein results in increased transport of Calcium [[USP2 gene mutant form results in increased expression of NHERF4 protein] which results in increased activity of TRPV6 protein] which results in increased uptake of Calcium TRPV6 protein results in increased uptake of Calcium 4-O-methyl-12-O-tetradecanoylphorbol 13-acetate inhibits the reaction [Tamoxifen inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]]; Cadmium inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]; calphostin C inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]; Gadolinium inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]; Lanthanum inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]; Tamoxifen inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]; TRPV6 protein promotes the reaction [Capsaicin results in increased abundance of Calcium] Calcium deficiency results in increased expression of TRPV6 mRNA |
CTD |
PMID:12584203 PMID:17292493 PMID:18648087 PMID:19996302 PMID:21146870 PMID:26756164 More...
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NCBI chr 7:142,871,208...142,885,745
Ensembl chr 7:142,871,208...142,885,745
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G |
TXN2 |
thioredoxin 2 |
decreases response to substance |
EXP |
TXN2 protein results in decreased susceptibility to Calcium |
CTD |
PMID:18550601 |
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NCBI chr22:36,467,046...36,481,640
Ensembl chr22:36,467,046...36,481,640
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G |
UBB |
ubiquitin B |
affects expression |
ISO |
Calcium affects the expression of UBB mRNA |
CTD |
PMID:15913539 |
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NCBI chr17:16,380,779...16,382,745
Ensembl chr17:16,380,798...16,382,745
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G |
UBE2D2 |
ubiquitin conjugating enzyme E2 D2 |
affects expression |
ISO |
Calcium affects the expression of UBE2D2 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 5:139,526,240...139,628,434
Ensembl chr 5:139,526,431...139,628,434
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G |
UBE2G1 |
ubiquitin conjugating enzyme E2 G1 |
affects expression multiple interactions |
ISO |
Calcium affects the expression of UBE2G1 mRNA [Calcium co-treated with Calcitriol] affects the expression of UBE2G1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr17:4,269,259...4,366,675
Ensembl chr17:4,269,259...4,366,675
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G |
UBE2I |
ubiquitin conjugating enzyme E2 I |
affects expression |
ISO |
Calcium affects the expression of UBE2I mRNA |
CTD |
PMID:15913539 |
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NCBI chr16:1,309,152...1,327,017
Ensembl chr16:1,291,444...1,327,018
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G |
UBTF |
upstream binding transcription factor |
affects expression |
ISO |
Calcium affects the expression of UBTF mRNA alternative form |
CTD |
PMID:15913539 |
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NCBI chr17:44,205,040...44,221,304
Ensembl chr17:44,205,033...44,221,626
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G |
UCN |
urocortin |
multiple interactions |
ISO |
astressin inhibits the reaction [UCN protein inhibits the reaction [Thapsigargin results in increased uptake of Calcium]]; UCN protein inhibits the reaction [Thapsigargin results in increased uptake of Calcium] |
CTD |
PMID:17885217 |
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NCBI chr 2:27,307,400...27,308,445
Ensembl chr 2:27,307,400...27,308,445
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G |
UMOD |
uromodulin |
affects binding |
EXP |
UMOD protein binds to Calcium |
CTD |
PMID:35263610 |
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NCBI chr16:20,333,051...20,356,301
Ensembl chr16:20,333,051...20,356,301
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G |
USP15 |
ubiquitin specific peptidase 15 |
multiple interactions |
EXP |
Calcium affects the reaction [Morphine results in increased expression of USP15 mRNA] |
CTD |
PMID:24068670 |
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NCBI chr12:62,260,404...62,416,389
Ensembl chr12:62,260,338...62,417,431
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G |
USP2 |
ubiquitin specific peptidase 2 |
multiple interactions |
ISO |
[[USP2 gene mutant form results in increased expression of NHERF4 protein] which results in increased activity of TRPV6 protein] which results in increased uptake of Calcium |
CTD |
PMID:26756164 |
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NCBI chr11:119,355,215...119,381,690
Ensembl chr11:119,355,215...119,381,711
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G |
VDAC1 |
voltage dependent anion channel 1 |
multiple interactions |
ISO |
[Calcium co-treated with Calcitriol] affects the expression of VDAC1 mRNA |
CTD |
PMID:15913539 |
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NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975
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G |
VDR |
vitamin D receptor |
affects metabolic processing affects abundance affects expression affects response to substance |
EXP ISO |
VDR gene polymorphism affects the metabolism of Calcium VDR protein affects the abundance of Calcium Calcium affects the expression of VDR mRNA VDR gene polymorphism affects the susceptibility to Calcium |
CTD |
PMID:11500311 PMID:15861036 PMID:15883634 PMID:15913539 PMID:16048257 |
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NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048
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G |
VEGFA |
vascular endothelial growth factor A |
affects expression increases abundance multiple interactions |
ISO EXP |
Calcium affects the expression of VEGFA mRNA VEGFA protein results in increased abundance of Calcium [VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium; TRPC6 protein promotes the reaction [[VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium]; VEGFA protein promotes the reaction [[Diglycerides results in increased activity of TRPC6 protein] which results in increased abundance of Calcium] |
CTD |
PMID:14551041 PMID:15913539 PMID:30524369 |
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NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
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G |
VIM |
vimentin |
multiple interactions |
ISO |
Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of VIM protein] |
CTD |
PMID:21879721 |
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NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593
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G |
VIP |
vasoactive intestinal peptide |
decreases abundance |
ISO |
VIP protein results in decreased abundance of Calcium |
CTD |
PMID:21039959 |
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NCBI chr 6:152,750,797...152,759,760
Ensembl chr 6:152,750,797...152,759,765
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G |
WNT5A |
Wnt family member 5A |
increases secretion multiple interactions increases expression |
EXP |
Calcium results in increased secretion of WNT5A protein CASR mutant form inhibits the reaction [Calcium results in increased expression of WNT5A protein]; WNT5A protein promotes the reaction [Calcium results in increased expression of KRT1 mRNA]; WNT5A protein promotes the reaction [Calcium results in increased expression of KRT1 protein]; WNT5A protein promotes the reaction [Calcium results in increased expression of LORICRIN mRNA]; WNT5A protein promotes the reaction [Calcium results in increased expression of LORICRIN protein] Calcium results in increased expression of WNT5A mRNA |
CTD |
PMID:24658506 |
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NCBI chr 3:55,465,715...55,505,263
Ensembl chr 3:55,465,715...55,490,539
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G |
YWHAZ |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta |
affects expression |
ISO |
Calcium affects the expression of YWHAZ mRNA |
CTD |
PMID:15913539 |
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NCBI chr 8:100,916,523...100,953,382
Ensembl chr 8:100,916,523...100,953,388
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G |
ABCA1 |
ATP binding cassette subfamily A member 1 |
decreases expression multiple interactions |
EXP |
Rosuvastatin Calcium results in decreased expression of ABCA1 mRNA Lipopolysaccharides inhibits the reaction [Rosuvastatin Calcium results in decreased expression of ABCA1 mRNA] |
CTD |
PMID:18192897 |
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NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155
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G |
ABCB11 |
ATP binding cassette subfamily B member 11 |
multiple interactions |
EXP ISO |
Rosuvastatin Calcium inhibits the reaction [ABCB11 protein affects the import of Taurocholic Acid] [Cyclosporine results in decreased activity of ABCB11 protein] which results in decreased secretion of Rosuvastatin Calcium; [Glyburide results in decreased activity of ABCB11 protein] which results in decreased secretion of Rosuvastatin Calcium; [troglitazone results in decreased activity of ABCB11 protein] which results in decreased secretion of Rosuvastatin Calcium |
CTD |
PMID:15901796 PMID:19853032 |
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NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324
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G |
ABCC2 |
ATP binding cassette subfamily C member 2 |
multiple interactions increases expression affects secretion |
EXP ISO |
ABCC2 protein binds to and results in increased uptake of Rosuvastatin Calcium analog; Rosuvastatin Calcium analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein] Rosuvastatin Calcium results in increased expression of ABCC2 protein [Benzbromarone results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium; [Probenecid results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium; [Sulfasalazine results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium; ABCC2 protein binds to and results in increased uptake of Rosuvastatin Calcium analog; Rosuvastatin Calcium analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Rosuvastatin Calcium promotes the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein] ABCC2 protein affects the secretion of Rosuvastatin Calcium |
CTD |
PMID:19853032 PMID:23562342 PMID:24909372 |
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NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
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G |
ABCC3 |
ATP binding cassette subfamily C member 3 |
increases expression |
ISO |
Rosuvastatin Calcium results in increased expression of ABCC3 protein |
CTD |
PMID:24909372 |
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NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253
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G |
ABCG1 |
ATP binding cassette subfamily G member 1 |
decreases expression |
EXP |
Rosuvastatin Calcium results in decreased expression of ABCG1 mRNA |
CTD |
PMID:18192897 |
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NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,297,244
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G |
ABCG2 |
ATP binding cassette subfamily G member 2 (JR blood group) |
multiple interactions increases activity |
ISO EXP |
[Novobiocin results in decreased activity of ABCG2 protein] which results in decreased secretion of Rosuvastatin Calcium Rosuvastatin Calcium results in increased activity of ABCG2 protein |
CTD |
PMID:19853032 PMID:30083819 |
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NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
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G |
ACHE |
acetylcholinesterase (Yt blood group) |
multiple interactions |
ISO |
[Piracetam co-treated with Rosuvastatin Calcium] inhibits the reaction [[Sodium Chloride, Dietary co-treated with Cholesterol, Dietary co-treated with Coconut Oil] results in increased activity of ACHE protein]; Rosuvastatin Calcium inhibits the reaction [[Sodium Chloride, Dietary co-treated with Cholesterol, Dietary co-treated with Coconut Oil] results in increased activity of ACHE protein] |
CTD |
PMID:28441890 |
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NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
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G |
AKT1 |
AKT serine/threonine kinase 1 |
affects phosphorylation |
ISO |
Rosuvastatin Calcium affects the phosphorylation of AKT1 protein |
CTD |
PMID:27815113 |
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NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
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G |
APOA1 |
apolipoprotein A1 |
multiple interactions increases expression |
EXP |
Niacin promotes the reaction [Rosuvastatin Calcium results in increased expression of APOA1 protein] |
CTD |
PMID:12767421 PMID:15539964 |
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NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622
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G |
APOB |
apolipoprotein B |
decreases expression |
EXP |
Rosuvastatin Calcium results in decreased expression of APOB protein |
CTD |
PMID:15539964 PMID:18702965 |
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NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073
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G |
BAX |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO |
Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in increased expression of BAX mRNA] |
CTD |
PMID:32007421 |
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NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
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G |
BCL2 |
BCL2 apoptosis regulator |
decreases expression |
EXP |
Rosuvastatin Calcium results in decreased expression of BCL2 protein |
CTD |
PMID:20852871 |
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NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
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G |
C3 |
complement C3 |
decreases expression |
ISO |
Rosuvastatin Calcium results in decreased expression of C3 mRNA |
CTD |
PMID:32771489 |
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NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
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G |
CASP3 |
caspase 3 |
increases activity increases expression |
EXP ISO |
Rosuvastatin Calcium results in increased activity of CASP3 protein Rosuvastatin Calcium results in increased expression of CASP3 protein |
CTD |
PMID:21478229 PMID:32771489 |
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NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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G |
CAT |
catalase |
increases activity multiple interactions |
ISO |
Rosuvastatin Calcium results in increased activity of CAT protein [Rosuvastatin Calcium co-treated with Isoproterenol] inhibits the reaction [Interleukin-6 results in increased expression of CAT protein]; Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in decreased activity of CAT protein] |
CTD |
PMID:20146376 PMID:32007421 PMID:35130744 |
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NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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G |
CCL2 |
C-C motif chemokine ligand 2 |
decreases expression |
ISO |
Rosuvastatin Calcium results in decreased expression of CCL2 mRNA |
CTD |
PMID:15681303 |
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NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
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G |
CREB5 |
cAMP responsive element binding protein 5 |
decreases expression |
EXP |
Rosuvastatin Calcium results in decreased expression of CREB5 mRNA |
CTD |
PMID:18192897 |
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NCBI chr 7:28,299,321...28,825,894
Ensembl chr 7:28,299,321...28,825,894
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G |
CRP |
C-reactive protein |
multiple interactions |
EXP |
Rosuvastatin Calcium inhibits the reaction [CRP protein results in decreased expression of NOS3] |
CTD |
PMID:21562509 |
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NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
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G |
CYBA |
cytochrome b-245 alpha chain |
multiple interactions decreases expression |
ISO |
[[[Rosuvastatin Calcium results in decreased expression of CYBB] co-treated with [Rosuvastatin Calcium results in decreased expression of CYBA]] co-treated with [Rosuvastatin Calcium results in increased expression of SOD1]] results in decreased abundance of Reactive Oxygen Species |
CTD |
PMID:21562509 |
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NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083
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G |
CYBB |
cytochrome b-245 beta chain |
multiple interactions decreases expression |
ISO |
Rosuvastatin Calcium inhibits the reaction [Nitroglycerin results in increased expression of CYBB mRNA] [[[Rosuvastatin Calcium results in decreased expression of CYBB] co-treated with [Rosuvastatin Calcium results in decreased expression of CYBA]] co-treated with [Rosuvastatin Calcium results in increased expression of SOD1]] results in decreased abundance of Reactive Oxygen Species |
CTD |
PMID:16633368 PMID:21562509 |
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NCBI chr X:37,780,059...37,813,461
Ensembl chr X:37,780,018...37,813,461
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G |
ESR1 |
estrogen receptor 1 |
decreases expression |
ISO |
Rosuvastatin Calcium results in decreased expression of ESR1 protein |
CTD |
PMID:32771489 |
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NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
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G |
GCLC |
glutamate-cysteine ligase catalytic subunit |
increases expression multiple interactions |
EXP |
Rosuvastatin Calcium results in increased expression of GCLC mRNA [Tetradecanoylphorbol Acetate co-treated with Rosuvastatin Calcium] results in increased expression of GCLC mRNA |
CTD |
PMID:18154958 |
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NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
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G |
GPR183 |
G protein-coupled receptor 183 |
multiple interactions increases expression |
EXP |
Lipopolysaccharides inhibits the reaction [Rosuvastatin Calcium results in increased expression of GPR183 mRNA] |
CTD |
PMID:18192897 |
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NCBI chr13:99,294,539...99,307,399
Ensembl chr13:99,294,539...99,307,399
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G |
GZMK |
granzyme K |
multiple interactions increases expression |
EXP |
Lipopolysaccharides inhibits the reaction [Rosuvastatin Calcium results in increased expression of GZMK mRNA] |
CTD |
PMID:18192897 |
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NCBI chr 5:55,024,256...55,034,570
Ensembl chr 5:55,024,256...55,034,570
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G |
HNF4A |
hepatocyte nuclear factor 4 alpha |
increases secretion |
ISO |
HNF4A protein results in increased secretion of Rosuvastatin Calcium |
CTD |
PMID:27160211 |
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NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,699...44,432,845
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G |
IL18RAP |
interleukin 18 receptor accessory protein |
decreases expression multiple interactions |
EXP |
Rosuvastatin Calcium results in decreased expression of IL18RAP mRNA Lipopolysaccharides inhibits the reaction [Rosuvastatin Calcium results in decreased expression of IL18RAP mRNA] |
CTD |
PMID:18192897 |
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NCBI chr 2:102,418,621...102,452,565
Ensembl chr 2:102,418,689...102,452,565
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G |
IL1B |
interleukin 1 beta |
decreases expression |
ISO |
Rosuvastatin Calcium results in decreased expression of IL1B mRNA |
CTD |
PMID:15681303 |
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NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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G |
KCNH2 |
potassium voltage-gated channel subfamily H member 2 |
decreases activity |
EXP |
Rosuvastatin Calcium results in decreased activity of KCNH2 protein |
CTD |
PMID:28551711 |
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NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321
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G |
KCNJ15 |
potassium inwardly rectifying channel subfamily J member 15 |
decreases expression |
EXP |
Rosuvastatin Calcium results in decreased expression of KCNJ15 mRNA |
CTD |
PMID:18192897 |
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NCBI chr21:38,229,926...38,307,357
Ensembl chr21:38,155,549...38,307,357
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G |
KDR |
kinase insert domain receptor |
multiple interactions |
ISO |
Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of KDR protein] |
CTD |
PMID:27097221 |
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NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595
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G |
MB |
myoglobin |
affects expression |
ISO |
Rosuvastatin Calcium affects the expression of MB protein |
CTD |
PMID:27815113 |
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NCBI chr22:35,606,764...35,623,354
Ensembl chr22:35,606,764...35,637,951
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G |
MSTN |
myostatin |
increases expression |
ISO |
Rosuvastatin Calcium results in increased expression of MSTN protein |
CTD |
PMID:33034787 |
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NCBI chr 2:190,055,700...190,062,729
Ensembl chr 2:190,055,700...190,062,729
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G |
NFE2L2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
ISO |
Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in decreased expression of NFE2L2 mRNA] |
CTD |
PMID:32007421 PMID:35130744 |
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NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
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G |
NOS2 |
nitric oxide synthase 2 |
increases expression multiple interactions |
ISO |
Rosuvastatin Calcium results in increased expression of NOS2 mRNA Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in increased expression of NOS2 mRNA] |
CTD |
PMID:21443142 PMID:32007421 PMID:35130744 |
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NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
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G |
NOS3 |
nitric oxide synthase 3 |
multiple interactions increases expression affects response to substance |
EXP ISO |
Rosuvastatin Calcium inhibits the reaction [CRP protein results in decreased expression of NOS3]; Rosuvastatin Calcium results in increased phosphorylation of and results in increased activity of NOS3 protein Rosuvastatin Calcium results in increased expression of NOS3 mRNA NOS3 protein affects the susceptibility to Rosuvastatin Calcium |
CTD |
PMID:12354446 PMID:15681303 PMID:18162361 PMID:21562509 |
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NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
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G |
ORM1 |
orosomucoid 1 |
multiple interactions decreases expression |
EXP |
Lipopolysaccharides inhibits the reaction [Rosuvastatin Calcium results in decreased expression of ORM1 mRNA] |
CTD |
PMID:18192897 |
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NCBI chr 9:114,323,098...114,326,479
Ensembl chr 9:114,323,098...114,326,479
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G |
PECAM1 |
platelet and endothelial cell adhesion molecule 1 |
multiple interactions |
ISO |
Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PECAM1 protein] |
CTD |
PMID:27097221 |
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NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776
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G |
PI3 |
peptidase inhibitor 3 |
decreases expression |
EXP |
Rosuvastatin Calcium results in decreased expression of PI3 mRNA |
CTD |
PMID:18192897 |
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NCBI chr20:45,174,902...45,176,544
Ensembl chr20:45,174,902...45,176,544
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G |
SELP |
selectin P |
decreases expression |
ISO |
Rosuvastatin Calcium results in decreased expression of SELP mRNA |
CTD |
PMID:15681303 |
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NCBI chr 1:169,588,849...169,630,124
Ensembl chr 1:169,588,849...169,630,193
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G |
SERPINE2 |
serpin family E member 2 |
multiple interactions |
ISO |
Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SERPINE2 protein]; Rosuvastatin Calcium inhibits the reaction [[TGFB1 protein co-treated with Serotonin] results in increased secretion of SERPINE2 protein] |
CTD |
PMID:27097221 |
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NCBI chr 2:223,975,045...224,039,286
Ensembl chr 2:223,975,045...224,039,318
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G |
SLCO1A2 |
solute carrier organic anion transporter family member 1A2 |
increases uptake multiple interactions decreases expression |
EXP ISO |
SLCO1A2 protein results in increased uptake of Rosuvastatin Calcium SLCO1A4 protein results in increased uptake of Rosuvastatin Calcium Fusidic Acid inhibits the reaction [SLCO1A4 protein results in increased uptake of Rosuvastatin Calcium] Rosuvastatin Calcium results in decreased expression of SLCO1A4 protein diosmetin inhibits the reaction [SLCO1A2 protein results in increased uptake of Rosuvastatin Calcium] |
CTD |
PMID:24909372 PMID:26888941 PMID:28867436 |
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NCBI chr12:21,264,600...21,419,634
Ensembl chr12:21,264,600...21,419,594
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G |
SLCO1B1 |
solute carrier organic anion transporter family member 1B1 |
multiple interactions increases uptake |
EXP |
Fusidic Acid inhibits the reaction [SLCO1B1 protein results in increased uptake of Rosuvastatin Calcium]; Rifampin inhibits the reaction [SLCO1B1 protein results in increased uptake of and results in increased susceptibility to Rosuvastatin Calcium]; SLCO1B1 protein results in increased uptake of and results in increased susceptibility to Rosuvastatin Calcium |
CTD |
PMID:23564645 PMID:26888941 PMID:31299240 |
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NCBI chr12:21,131,194...21,239,796
Ensembl chr12:21,131,194...21,239,796
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G |
SLCO1B3 |
solute carrier organic anion transporter family member 1B3 |
multiple interactions increases uptake |
EXP ISO |
Fusidic Acid inhibits the reaction [SLCO1B3 protein results in increased uptake of Rosuvastatin Calcium] Fusidic Acid inhibits the reaction [SLCO1B2 protein results in increased uptake of Rosuvastatin Calcium] |
CTD |
PMID:26888941 PMID:31299240 |
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NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911
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G |
SLCO2B1 |
solute carrier organic anion transporter family member 2B1 |
multiple interactions increases uptake |
EXP |
Rutin promotes the reaction [SLCO2B1 protein results in increased uptake of Rosuvastatin Calcium] |
CTD |
PMID:24285294 |
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NCBI chr11:75,151,107...75,206,549
Ensembl chr11:75,100,563...75,206,549
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G |
SOD1 |
superoxide dismutase 1 |
multiple interactions increases expression |
ISO |
[[[Rosuvastatin Calcium results in decreased expression of CYBB] co-treated with [Rosuvastatin Calcium results in decreased expression of CYBA]] co-treated with [Rosuvastatin Calcium results in increased expression of SOD1]] results in decreased abundance of Reactive Oxygen Species |
CTD |
PMID:21562509 |
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NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
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G |
TFF1 |
trefoil factor 1 |
decreases expression |
ISO |
Rosuvastatin Calcium results in decreased expression of TFF1 mRNA |
CTD |
PMID:32771489 |
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NCBI chr21:42,362,282...42,366,535
Ensembl chr21:42,362,282...42,366,535
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G |
TGFB1 |
transforming growth factor beta 1 |
multiple interactions decreases expression |
ISO |
Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; Rosuvastatin Calcium inhibits the reaction [[TGFB1 protein co-treated with Serotonin] results in increased secretion of SERPINE2 protein] Rosuvastatin Calcium results in decreased expression of TGFB1 mRNA |
CTD |
PMID:15681303 PMID:27097221 |
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NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
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G |
TNF |
tumor necrosis factor |
decreases expression multiple interactions |
ISO |
Rosuvastatin Calcium results in decreased expression of TNF mRNA Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in increased expression of TNF protein] |
CTD |
PMID:15681303 PMID:32007421 PMID:35130744 |
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NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
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G |
TNNI3 |
troponin I3, cardiac type |
multiple interactions |
ISO |
Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in increased expression of TNNI3 protein] |
CTD |
PMID:32007421 PMID:35130744 |
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NCBI chr19:55,151,767...55,157,732
Ensembl chr19:55,151,767...55,157,773
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G |
VNN3P |
vanin 3, pseudogene |
decreases expression |
EXP |
Rosuvastatin Calcium results in decreased expression of VNN3P mRNA |
CTD |
PMID:18192897 |
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NCBI chr 6:132,722,787...132,734,765
Ensembl chr 6:132,722,784...132,736,935 Ensembl chr 6:132,722,784...132,736,935
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G |
WT1 |
WT1 transcription factor |
increases expression |
ISO |
Rosuvastatin Calcium results in increased expression of WT1 mRNA |
CTD |
PMID:21443142 |
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NCBI chr11:32,387,775...32,435,539
Ensembl chr11:32,387,775...32,435,564
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G |
DNM1L |
dynamin 1 like |
increases expression |
ISO |
tricalcium phosphate results in increased expression of DNM1L protein |
CTD |
PMID:37678662 |
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NCBI chr12:32,679,301...32,745,650
Ensembl chr12:32,679,200...32,745,650
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G |
HMOX1 |
heme oxygenase 1 |
decreases expression |
ISO |
tricalcium phosphate results in decreased expression of HMOX1 protein |
CTD |
PMID:37678662 |
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NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
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G |
MAP1LC3B |
microtubule associated protein 1 light chain 3 beta |
multiple interactions affects localization |
ISO |
Acetylcysteine inhibits the reaction [tricalcium phosphate affects the localization of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [tricalcium phosphate results in increased expression of MAP1LC3B protein] |
CTD |
PMID:37678662 |
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NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
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G |
MFN2 |
mitofusin 2 |
decreases expression |
ISO |
tricalcium phosphate results in decreased expression of MFN2 protein |
CTD |
PMID:37678662 |
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NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211
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G |
MLKL |
mixed lineage kinase domain like pseudokinase |
increases phosphorylation multiple interactions |
ISO |
tricalcium phosphate results in increased phosphorylation of MLKL protein Acetylcysteine inhibits the reaction [tricalcium phosphate results in increased phosphorylation of MLKL protein]; N-(4-(N-(3-methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophene-2-yl)acrylamide inhibits the reaction [tricalcium phosphate results in increased phosphorylation of MLKL protein]; necrostatin-1 inhibits the reaction [tricalcium phosphate results in increased phosphorylation of MLKL protein] |
CTD |
PMID:37678662 |
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NCBI chr16:74,671,855...74,700,862
Ensembl chr16:74,671,855...74,700,960
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G |
NFE2L2 |
NFE2 like bZIP transcription factor 2 |
decreases expression |
ISO |
tricalcium phosphate results in decreased expression of NFE2L2 protein |
CTD |
PMID:37678662 |
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NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
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G |
NQO1 |
NAD(P)H quinone dehydrogenase 1 |
decreases expression |
ISO |
tricalcium phosphate results in decreased expression of NQO1 protein |
CTD |
PMID:37678662 |
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NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
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G |
PINK1 |
PTEN induced kinase 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [tricalcium phosphate results in increased expression of PINK1 protein]; tricalcium phosphate results in increased expression of and results in increased localization of PINK1 protein |
CTD |
PMID:37678662 |
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NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511
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G |
RIPK1 |
receptor interacting serine/threonine kinase 1 |
multiple interactions increases phosphorylation |
ISO |
Acetylcysteine inhibits the reaction [tricalcium phosphate results in increased phosphorylation of RIPK1 protein]; N-(4-(N-(3-methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophene-2-yl)acrylamide inhibits the reaction [tricalcium phosphate results in increased phosphorylation of RIPK1 protein]; necrostatin-1 inhibits the reaction [tricalcium phosphate results in increased phosphorylation of RIPK1 protein] |
CTD |
PMID:37678662 |
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NCBI chr 6:3,063,967...3,115,187
Ensembl chr 6:3,063,824...3,115,187
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G |
RIPK3 |
receptor interacting serine/threonine kinase 3 |
multiple interactions increases phosphorylation |
ISO |
Acetylcysteine inhibits the reaction [tricalcium phosphate results in increased phosphorylation of RIPK3 protein]; N-(4-(N-(3-methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophene-2-yl)acrylamide inhibits the reaction [tricalcium phosphate results in increased phosphorylation of RIPK3 protein]; necrostatin-1 inhibits the reaction [tricalcium phosphate results in increased phosphorylation of RIPK3 protein] |
CTD |
PMID:37678662 |
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NCBI chr14:24,336,025...24,339,991
Ensembl chr14:24,336,025...24,340,022
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G |
SQSTM1 |
sequestosome 1 |
decreases expression multiple interactions |
ISO |
tricalcium phosphate results in decreased expression of SQSTM1 protein Acetylcysteine inhibits the reaction [tricalcium phosphate results in decreased expression of SQSTM1 protein] |
CTD |
PMID:37678662 |
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NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
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G |
TXN |
thioredoxin |
decreases expression |
ISO |
tricalcium phosphate results in decreased expression of TXN1 protein |
CTD |
PMID:37678662 |
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NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507
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G |
TXNIP |
thioredoxin interacting protein |
increases expression |
ISO |
tricalcium phosphate results in increased expression of TXNIP protein |
CTD |
PMID:37678662 |
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NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579
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