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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:calcium atom
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Accession:CHEBI:22984 term browser browse the term
Definition:An alkaline earth metal atom that has formula Ca.
Synonyms:related_synonym: 20Ca;   Ca;   Formula=Ca;   InChI=1S/Ca;   InChIKey=OYPRJOBELJOOCE-UHFFFAOYSA-N;   Kalzium;   SMILES=[Ca];   calcio;   calcium
 xref: CAS:7440-70-2;   DrugBank:DB01373;   KEGG:C00076
 xref_mesh: MESH:D002118
 xref: WebElements:Ca



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calcium atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions ISO Calcium deficiency inhibits the reaction [ABCB11 protein results in increased export of Taurocholic Acid] CTD PMID:25862123 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO Calcium deficiency inhibits the reaction [ABCB1 protein results in increased export of Xanthenes]; Calcium inhibits the reaction [Magnesium results in increased activity of ABCB1 protein] CTD PMID:2900677 PMID:25862123 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO Calcium deficiency inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein] CTD PMID:25862123 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Aco2 aconitase 2 increases activity
multiple interactions
ISO Calcium results in increased activity of ACO2 protein
[Calcium results in increased activity of ACO2 protein] which results in increased reduction of thiazolyl blue; [Nicardipine results in decreased uptake of Calcium] which results in decreased activity of ACO2 protein
CTD PMID:12548706 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Actb actin, beta multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of ACTB mRNA CTD PMID:15913539 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Adcy5 adenylate cyclase 5 decreases activity
increases response to substance
ISO Calcium results in decreased activity of ADCY5 protein
ADCY5 protein results in increased susceptibility to Calcium
CTD PMID:12065575 PMID:12869393 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974
JBrowse link
G Adcy9 adenylate cyclase 9 multiple interactions ISO Calcium inhibits the reaction [Miconazole results in increased activity of ADCY9 protein]; Tacrolimus inhibits the reaction [Calcium inhibits the reaction [Miconazole results in increased activity of ADCY9 protein]] CTD PMID:30607468 NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 increases abundance
affects abundance
multiple interactions
EXP ADCYAP1 protein results in increased abundance of Calcium
ADCYAP1 protein affects the abundance of Calcium
Calcium affects the reaction [ADCYAP1 protein results in increased expression of SELENOT mRNA]; SELENOT protein affects the reaction [ADCYAP1 protein results in increased abundance of Calcium]
CTD PMID:18198219 PMID:21039959 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773
JBrowse link
G Adgrl1 adhesion G protein-coupled receptor L1 multiple interactions EXP [alpha-latrotoxin binds to ADGRL1 protein] which results in increased uptake of Calcium; [black widow spider venom binds to ADGRL1 protein] which results in increased uptake of Calcium CTD PMID:10026162 NCBI chr19:24,202,405...24,244,137
Ensembl chr19:24,204,360...24,244,139
JBrowse link
G Adgrl2 adhesion G protein-coupled receptor L2 multiple interactions EXP [alpha-latrotoxin binds to ADGRL2 protein] which results in increased uptake of Calcium; [black widow spider venom binds to ADGRL2 protein] which results in increased uptake of Calcium CTD PMID:10026162 NCBI chr 2:237,696,055...238,327,141
Ensembl chr 2:237,696,056...238,327,141
JBrowse link
G Adm adrenomedullin decreases expression ISO Calcium results in decreased expression of ADM mRNA CTD PMID:20682585 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Adra1a adrenoceptor alpha 1A multiple interactions
affects transport
EXP
ISO
[Epinephrine binds to and results in increased activity of ADRA1A protein] which results in increased transport of Calcium; [Phenylephrine binds to and results in increased activity of ADRA1A protein] which results in increased transport of Calcium; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of EIF4EBP1 protein]; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of MTOR protein]; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of RPS6KB1 protein]
5-methylurapidil inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; [A 61603 results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Epinephrine binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Oxymetazoline binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]
ADRA1A protein affects the transport of Calcium
CTD PMID:12935885 PMID:15306222 PMID:15639650 PMID:15672411 PMID:16498073 More... NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
JBrowse link
G Adra1b adrenoceptor alpha 1B multiple interactions ISO [Epinephrine binds to and results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; [Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium] CTD PMID:15306222 PMID:16498073 PMID:20030735 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
JBrowse link
G Adra1d adrenoceptor alpha 1D multiple interactions ISO [Epinephrine binds to and results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; [Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium] CTD PMID:15306222 PMID:20030735 NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354
JBrowse link
G Adra2a adrenoceptor alpha 2A multiple interactions ISO [Epinephrine binds to and results in increased activity of ADRA2A protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA2A protein] which results in increased abundance of Calcium CTD PMID:20030735 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
JBrowse link
G Adra2b adrenoceptor alpha 2B multiple interactions ISO [Epinephrine binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; [Oxymetazoline binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; [xylometazoline binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium CTD PMID:20030735 NCBI chr 3:114,585,174...114,589,220
Ensembl chr 3:114,585,169...114,589,355
JBrowse link
G Adra2c adrenoceptor alpha 2C multiple interactions ISO [Epinephrine binds to and results in increased activity of ADRA2C protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA2C protein] which results in increased abundance of Calcium CTD PMID:20030735 NCBI chr14:75,471,143...75,472,846
Ensembl chr14:75,471,143...75,472,846
JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions EXP
ISO
[Terbutaline binds to and results in increased activity of ADRB2 protein] which affects the abundance of Calcium
[Benzo(a)pyrene binds to ADRB2 protein] which results in increased transport of Calcium; ADRB2 protein promotes the reaction [Benzo(a)pyrene results in increased transport of Calcium]
CTD PMID:10372813 PMID:22167199 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Ago2 argonaute RISC catalytic component 2 multiple interactions EXP Calcium affects the reaction [PICK1 protein binds to AGO2 protein]; Calcium deficiency inhibits the reaction [Excitatory Amino Acid Agonists inhibits the reaction [PICK1 protein binds to AGO2 protein]] CTD PMID:28404816 NCBI chr 7:105,018,202...105,105,120
Ensembl chr 7:105,029,120...105,104,974
JBrowse link
G Agt angiotensinogen increases uptake
affects localization
multiple interactions
increases abundance
ISO
EXP
AGT protein results in increased uptake of Calcium
AGT protein affects the localization of Calcium
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [AGT protein affects the localization of Calcium]; bafilomycin A1 inhibits the reaction [AGT protein affects the localization of Calcium]; Heparin inhibits the reaction [AGT protein affects the localization of Calcium]; Losartan inhibits the reaction [AGT protein affects the localization of Calcium]; Saralasin inhibits the reaction [AGT protein affects the localization of Calcium]; Sirolimus inhibits the reaction [AGT protein affects the localization of Calcium]; xestospongin C inhibits the reaction [AGT protein affects the localization of Calcium]
[AGT protein results in increased abundance of Calcium] which results in increased abundance of Reactive Oxygen Species
Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]
benidipine inhibits the reaction [AGT protein results in increased uptake of Calcium]; Mibefradil inhibits the reaction [AGT protein results in increased uptake of Calcium]
CTD PMID:10660688 PMID:18331727 PMID:18854758 PMID:21613610 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr1a angiotensin II receptor, type 1a affects expression EXP Calcium affects the expression of AGTR1A mRNA CTD PMID:15913539 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Agtr1b angiotensin II receptor, type 1b multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of AGTR1B mRNA CTD PMID:15913539 NCBI chr 2:102,844,969...102,920,232
Ensembl chr 2:102,844,969...102,920,232
JBrowse link
G Akap1 A-kinase anchoring protein 1 affects expression EXP Calcium affects the expression of AKAP1 mRNA CTD PMID:15913539 NCBI chr10:73,621,021...73,654,123
Ensembl chr10:73,621,883...73,653,896
JBrowse link
G Akap11 A-kinase anchoring protein 11 affects expression EXP Calcium affects the expression of AKAP11 mRNA CTD PMID:15913539 NCBI chr15:53,911,635...53,956,138
Ensembl chr15:53,911,657...53,941,605
JBrowse link
G Akt1 AKT serine/threonine kinase 1 affects abundance
affects expression
multiple interactions
affects response to substance
ISO
EXP
AKT1 protein affects the abundance of Calcium
Calcium affects the expression of AKT1 mRNA
[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein; Calcium affects the reaction [P2RY1 protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; CAMKK2 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; PDK1 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; PX-866 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; STO 609 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; W 7 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]
AKT1 protein affects the susceptibility to Calcium
CTD PMID:15913539 PMID:16094411 PMID:16236484 PMID:28634229 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions ISO ALDH2 protein inhibits the reaction [Ethanol affects the abundance of Calcium]
Calcium affects the reaction [ALDH2 gene SNP affects the abundance of Lead]
CTD PMID:17590987 PMID:28212632 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Alg2 ALG2, alpha-1,3/1,6-mannosyltransferase affects binding ISO Calcium binds to ALG2 protein CTD PMID:18997320 NCBI chr 5:61,768,738...61,773,297
Ensembl chr 5:61,768,740...61,773,297
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions ISO Calcium promotes the reaction [L 708714 binds to ALOX5 protein] CTD PMID:7577949 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Alpp alkaline phosphatase, placental affects binding ISO Calcium binds to ALPP protein CTD PMID:16815919 NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606
JBrowse link
G Ano1 anoctamin 1 multiple interactions
increases activity
ISO 9-phenanthrol inhibits the reaction [Calcium results in increased activity of ANO1 protein] CTD PMID:25573456 NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069
JBrowse link
G Anxa1 annexin A1 affects activity EXP Calcium affects the activity of ANXA1 protein CTD PMID:20655937 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Anxa5 annexin A5 multiple interactions ISO Calcium binds to and results in increased activity of ANXA5 protein; Calcium promotes the reaction [Phosphatidylserines binds to ANXA5 protein] CTD PMID:11578147 PMID:16076491 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Aoc1 amine oxidase, copper containing 1 affects binding ISO AOC1 protein binds to Calcium CTD PMID:12072962 NCBI chr 4:77,812,260...77,831,846
Ensembl chr 4:77,812,260...77,831,840
JBrowse link
G Apoe apolipoprotein E affects abundance
affects expression
ISO
EXP
APOE protein affects the abundance of Calcium
Calcium affects the expression of APOE mRNA
CTD PMID:15913539 PMID:17899169 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Apom apolipoprotein M affects expression EXP Calcium affects the expression of APOM mRNA CTD PMID:15913539 NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550
JBrowse link
G App amyloid beta precursor protein multiple interactions
increases uptake
affects abundance
ISO
EXP
2,4-Dinitrophenol affects the reaction [APP protein affects the abundance of Calcium]; 3-nitrophenol affects the reaction [APP protein affects the abundance of Calcium]; 4-anisidine affects the reaction [APP protein affects the abundance of Calcium]
APP protein modified form results in increased uptake of Calcium; APP protein results in increased uptake of Calcium
Calcium deficiency inhibits the reaction [APP protein modified form results in increased uptake of Calcium]; EDN3 protein inhibits the reaction [APP protein results in increased uptake of Calcium]; Flurbiprofen inhibits the reaction [APP protein results in increased uptake of Calcium]; Ibuprofen inhibits the reaction [APP protein results in increased uptake of Calcium]; Indomethacin inhibits the reaction [APP protein results in increased uptake of Calcium]; Nimodipine inhibits the reaction [APP protein results in increased uptake of Calcium]; Ruthenium Red inhibits the reaction [APP protein modified form results in increased uptake of Calcium]; Salicylates inhibits the reaction [APP protein results in increased uptake of Calcium]; sulindac sulfide inhibits the reaction [APP protein results in increased uptake of Calcium]
CTD PMID:12383957 PMID:18648507 PMID:18949129 PMID:24457011 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions ISO
EXP
ARRB2 protein affects the abundance of and affects the localization of Calcium
ARRB2 promotes the reaction [carvedilol results in increased uptake of Calcium]
CTD PMID:16210646 PMID:21078978 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of ATP1A1 mRNA CTD PMID:15913539 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 multiple interactions EXP Calcium affects the reaction [Ouabain results in increased expression of ATP1B1 mRNA] CTD PMID:11204457 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 affects transport
multiple interactions
EXP
ISO
ATP2A1 protein affects the transport of Calcium
[Phenols results in decreased activity of ATP2A1 protein] which results in decreased transport of Calcium
CTD PMID:11230109 PMID:18773882 NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 affects abundance
multiple interactions
affects transport
affects uptake
affects export
ISO
EXP
ATP2A2 protein affects the abundance of Calcium
Calcium promotes the reaction [Clioquinol results in decreased expression of ATP2A2 mRNA]; Calcium promotes the reaction [Clioquinol results in decreased expression of ATP2A2 protein]
ATP2A2 protein affects the transport of Calcium
[[Phenylephrine results in increased activity of SLC9A1 protein] which results in increased transport of Calcium] which results in increased expression of ATP2A2 protein; [Phenylephrine results in decreased expression of ATP2A2 protein] which results in decreased transport of Calcium; [Thapsigargin results in decreased activity of ATP2A2 protein] which results in decreased transport of Calcium
Calcium promotes the reaction [Clioquinol results in decreased expression of ATP2A2 mRNA]; Calcium promotes the reaction [Clioquinol results in decreased expression of ATP2A2 protein]; PPP3R1 gene mutant form inhibits the reaction [ATP2A2 protein affects the transport of Calcium]
ATP2A2 protein alternative form affects the uptake of Calcium
ATP2A2 protein alternative form affects the export of Calcium
CTD PMID:11679415 PMID:16236312 PMID:17287366 PMID:19244478 PMID:19328205 More... NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 multiple interactions
increases export
ISO caloxin 1b1 inhibits the reaction [ATP2B1 protein results in increased export of Calcium] CTD PMID:16452157 NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295
JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 increases export
multiple interactions
ISO ATP2B4 protein results in increased export of Calcium
caloxin 1b1 inhibits the reaction [ATP2B4 protein results in increased export of Calcium]
CTD PMID:16452157 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246
JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 multiple interactions EXP Calcium inhibits the reaction [ATP8B1 protein results in increased transport of Phosphatidylserines] CTD PMID:11584374 NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396
JBrowse link
G Avp arginine vasopressin multiple interactions
increases uptake
increases abundance
EXP 1-Butanol inhibits the reaction [AVP protein results in increased abundance of Calcium]; 2-(4-amylcinnamoyl)amino-4-chlorobenzoic acid inhibits the reaction [AVP protein results in increased abundance of Calcium]; [[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; [[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein; [AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium; [AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium; AVP protein results in increased import of and results in increased abundance of Calcium; Carvedilol inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium]; Chromium affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; Chromium affects the reaction [INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; chromium tripicolinate affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; chromium tripicolinate affects the reaction [INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; INS1 protein affects the reaction [Chromium affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; INS1 protein affects the reaction [chromium tripicolinate affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; Nicardipine inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium]; Nifedipine inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium] CTD PMID:9446840 PMID:11356622 PMID:11553362 PMID:14711191 PMID:21039959 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
JBrowse link
G Avpr1a arginine vasopressin receptor 1A multiple interactions EXP [[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; [[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein; [AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium; [NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium; Carbachol promotes the reaction [[NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium]; Nicardipine inhibits the reaction [[NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium]; Nicardipine inhibits the reaction [Carbachol promotes the reaction [[NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium]] CTD PMID:11553362 PMID:12646291 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215
JBrowse link
G Avpr2 arginine vasopressin receptor 2 affects expression EXP Calcium affects the expression of AVPR2 mRNA CTD PMID:15913539 NCBI chr  X:151,633,501...151,636,000
Ensembl chr  X:151,633,522...151,635,989
JBrowse link
G Axin1 axin 1 affects expression EXP Calcium affects the expression of AXIN1 mRNA CTD PMID:15913539 NCBI chr10:15,163,684...15,215,615
Ensembl chr10:15,163,684...15,215,615
JBrowse link
G Bad BCL2-associated agonist of cell death affects expression EXP Calcium affects the expression of BAD mRNA CTD PMID:15913539 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bdkrb1 bradykinin receptor B1 multiple interactions ISO
EXP
2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [[kallidin, des-Arg(10)- results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]; [kallidin, des-Arg(10)- results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium; Sodium affects the reaction [[kallidin, des-Arg(10)- results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]
[kallidin, des-Arg(10)- binds to and results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium; bradykinin, Lys-Leu(8)-desArg(9)- inhibits the reaction [[kallidin, des-Arg(10)- binds to and results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]; Indomethacin inhibits the reaction [[kallidin, des-Arg(10)- binds to and results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]
CTD PMID:15703175 PMID:22554775 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
JBrowse link
G Bdkrb2 bradykinin receptor B2 multiple interactions ISO BDKRB2 protein affects the reaction [KNG1 protein affects the abundance of Calcium]
BDKRB2 protein affects the reaction [pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]]
CTD PMID:16473424 PMID:18054572 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
increases transport
ISO [Cadmium results in decreased transport of Calcium] inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein]; Calcium affects the reaction [Oxygen deficiency results in increased secretion of BDNF protein]
BDNF protein results in increased transport of Calcium
3,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]; 3,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide promotes the reaction [Tetrodotoxin inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]]; Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]; Tetrodotoxin inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]
CTD PMID:16553631 PMID:26095976 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Best1 bestrophin 1 increases activity
multiple interactions
ISO Calcium results in increased activity of BEST1 protein
[PAR-1-activating peptide results in increased abundance of Calcium] which results in increased activity of BEST1 protein
CTD PMID:19828819 PMID:25573456 NCBI chr 1:206,629,340...206,646,085
Ensembl chr 1:206,629,500...206,646,063
JBrowse link
G Bmp4 bone morphogenetic protein 4 affects expression
multiple interactions
EXP
ISO
Calcium affects the expression of BMP4 mRNA
[Calcium binds to MGP protein] which binds to and results in decreased activity of BMP4 protein; [Edetic Acid inhibits the reaction [Calcium binds to MGP protein]] inhibits the reaction [MGP protein binds to BMP4 protein]
CTD PMID:15913539 PMID:18369157 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Btk Bruton tyrosine kinase affects transport ISO BTK protein affects the transport of Calcium CTD PMID:12848851 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853
JBrowse link
G C5 complement C5 multiple interactions ISO [C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium; resveratrol inhibits the reaction [[C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium] CTD PMID:19284563 PMID:19346296 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A increases transport
multiple interactions
EXP CACNA1A protein results in increased transport of Calcium
Allethrins inhibits the reaction [CACNA1A protein results in increased transport of Calcium]
CTD PMID:14634047 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225
JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B multiple interactions
decreases uptake
increases transport
EXP decamethrin inhibits the reaction [CACNA1B protein results in increased transport of Calcium]; decamethrin promotes the reaction [CACNA1B gene mutant form results in increased transport of Calcium]
CACNA1B protein alternative form results in decreased uptake of Calcium
CTD PMID:18383452 PMID:22891239 NCBI chr 3:7,380,892...7,546,104
Ensembl chr 3:7,380,922...7,546,091
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C increases transport
multiple interactions
ISO
EXP
CACNA1C protein results in increased transport of Calcium
[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium; [CACNA2D4 protein binds to CACNA1C protein binds to CACNB3 protein] which results in increased transport of Calcium; CACNA2D4 protein promotes the reaction [[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium]
Allethrins inhibits the reaction [CACNA1C protein results in increased transport of Calcium]
CTD PMID:12181424 PMID:14634047 PMID:15299022 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D affects transport
multiple interactions
ISO
EXP
CACNA1D protein affects the transport of Calcium
CACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Calcium]
[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium; [CACNA1D protein results in increased uptake of Calcium] which affects the localization of SLC2A2 protein; [CACNA1D protein results in increased uptake of Calcium] which results in increased phosphorylation of MYL9 protein; CACNA2D1 protein promotes the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]; gabapentin affects the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]; SLC5A1 protein affects the reaction [CACNA1D protein results in increased uptake of Calcium]
CTD PMID:15357422 PMID:17272349 PMID:19796812 PMID:27798183 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215
JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E increases transport
multiple interactions
ISO
EXP
CACNA1E protein results in increased transport of Calcium
Calcium inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]
Cadmium inhibits the reaction [CACNA1E protein results in increased transport of Calcium]; Nickel inhibits the reaction [CACNA1E protein results in increased transport of Calcium]
CTD PMID:10627594 PMID:10669483 PMID:12663092 NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450
JBrowse link
G Cacna1f calcium voltage-gated channel subunit alpha1 F increases transport ISO CACNA1F protein results in increased transport of Calcium CTD PMID:14744918 NCBI chr  X:14,868,096...14,896,413
Ensembl chr  X:14,868,024...14,896,413
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G increases transport
multiple interactions
ISO
EXP
CACNA1G protein results in increased transport of Calcium
Allethrins inhibits the reaction [CACNA1G protein results in increased transport of Calcium]
CACNG2 protein affects the reaction [CACNA1G protein results in increased transport of Calcium]; CACNG4 protein affects the reaction [CACNA1G protein results in increased transport of Calcium]; CACNG5 protein affects the reaction [CACNA1G protein results in increased transport of Calcium]
CTD PMID:10734232 PMID:11073957 PMID:14634047 NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H increases transport
multiple interactions
ISO
EXP
CACNA1H protein results in increased transport of Calcium
Amiloride inhibits the reaction [CACNA1H protein results in increased transport of Calcium]; Nickel inhibits the reaction [CACNA1H protein results in increased transport of Calcium]
Amiloride inhibits the reaction [CACNA1H protein results in increased transport of Calcium]; Mibefradil inhibits the reaction [CACNA1H protein results in increased transport of Calcium]; Nickel inhibits the reaction [CACNA1H protein results in increased transport of Calcium]
CTD PMID:9930755 PMID:11073957 PMID:11897840 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I increases transport EXP CACNA1I protein results in increased transport of Calcium CTD PMID:11073957 NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 multiple interactions
increases transport
ISO
EXP
[gabapentin results in decreased activity of CACNA2D1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]; CACNA2D1 protein affects the reaction [Potassium Chloride results in increased transport of Calcium]
CACNA2D1 protein promotes the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]
CACNA2D1 protein results in increased transport of Calcium
CTD PMID:15474003 PMID:17442347 PMID:17881535 PMID:19796812 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969
JBrowse link
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 affects transport
multiple interactions
ISO CACNA2D2 protein affects the transport of Calcium
CACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Calcium]
CTD PMID:14660671 PMID:27798183 NCBI chr 8:108,072,208...108,203,516
Ensembl chr 8:108,072,454...108,203,173
JBrowse link
G Cacna2d4 calcium voltage-gated channel auxiliary subunit alpha2delta 4 multiple interactions ISO [CACNA2D4 protein binds to CACNA1C protein binds to CACNB3 protein] which results in increased transport of Calcium; CACNA2D4 protein promotes the reaction [[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium] CTD PMID:12181424 NCBI chr 4:152,408,657...152,524,614
Ensembl chr 4:152,408,657...152,521,268
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 multiple interactions ISO
EXP
[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium; [CACNA2D4 protein binds to CACNA1C protein binds to CACNB3 protein] which results in increased transport of Calcium; CACNA2D4 protein promotes the reaction [[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium]
[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium; CACNA2D1 protein promotes the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]; gabapentin affects the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]
CTD PMID:12181424 PMID:19796812 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074
JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 multiple interactions ISO CACNG2 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] CTD PMID:10734232 NCBI chr 7:109,572,838...109,698,516
Ensembl chr 7:109,574,459...109,697,227
JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 multiple interactions ISO CACNG4 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] CTD PMID:10734232 NCBI chr10:92,686,100...92,745,601
Ensembl chr10:92,683,761...92,746,126
JBrowse link
G Cacng5 calcium voltage-gated channel auxiliary subunit gamma 5 multiple interactions ISO CACNG5 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] CTD PMID:10734232 NCBI chr10:92,827,441...92,869,632
Ensembl chr10:92,829,196...92,869,614
JBrowse link
G Calb1 calbindin 1 affects expression EXP Calcium affects the expression of CALB1 mRNA CTD PMID:15913539 NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431
JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions
increases expression
ISO
EXP
rimabotulinumtoxinB inhibits the reaction [[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein]; rimabotulinumtoxinB inhibits the reaction [[Potassium co-treated with Calcium] results in increased secretion of CALCA protein]
Calcium promotes the reaction [Lipopolysaccharides results in increased expression of CALCA mRNA]
Calcium results in increased expression of CALCA mRNA
Calcium results in increased expression of CALCA protein
[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein; [KNG1 protein alternative form co-treated with Calcium] results in increased secretion of CALCA protein; [Potassium co-treated with Calcium] results in increased secretion of CALCA protein; [Sumatriptan results in increased abundance of Calcium] inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA]; botulinum toxin type D inhibits the reaction [[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein]; botulinum toxin type D inhibits the reaction [[Potassium co-treated with Calcium] results in increased secretion of CALCA protein]; Botulinum Toxins, Type A inhibits the reaction [[Potassium co-treated with Calcium] results in increased secretion of CALCA protein]; Calcium affects the reaction [Capsaicin inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Calcium affects the reaction [Capsaicin inhibits the reaction [mustard oil results in increased secretion of CALCA protein]]; Calcium affects the reaction [mustard oil inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Calcium deficiency inhibits the reaction [safranal results in increased secretion of CALCA protein]; Calcium inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA]
CTD PMID:2470235 PMID:12574409 PMID:17590514 PMID:17666428 PMID:20682585 More... NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Calm1 calmodulin 1 multiple interactions
affects binding
EXP
ISO
[Calcium binds to CALM1 protein] promotes the reaction [NOS1 protein results in increased chemical synthesis of Nitric Oxide]; [Calcium binds to CALM1 protein] which binds to and affects the folding of and results in increased activity of NOS1 protein; Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]; Calcium affects the reaction [CALM1 protein modified form binds to and affects the activity of RYR1 protein]; Calcium binds to and affects the folding of CALM1 protein
Calcium affects the folding of [CALM1 protein binds to RYR1 protein modified form]; Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]
CTD PMID:15381065 PMID:15628869 PMID:17098364 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calr calreticulin affects response to substance
multiple interactions
ISO CALR protein affects the susceptibility to Calcium
CALR protein promotes the reaction [KNG1 protein modified form results in increased abundance of Calcium]
CTD PMID:7961812 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta affects expression
multiple interactions
EXP
ISO
Calcium affects the expression of CAMK2D mRNA
[Ionomycin co-treated with Calcium co-treated with CAMK2D protein] results in increased activity of TRPM4 protein
CTD PMID:15913539 PMID:33392831 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 multiple interactions ISO CAMKK2 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein] CTD PMID:28634229 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279
JBrowse link
G Capn1 calpain 1 multiple interactions
increases cleavage
increases activity
ISO
EXP
[Caffeine co-treated with Alprazolam] promotes the reaction [Calcium results in increased activity of CAPN1 protein]; [Calcium co-treated with CAPN1 protein] results in increased degradation of TP73 protein modified form; [sodium arsenite results in increased abundance of Arsenic] promotes the reaction [[Calcium results in increased cleavage of CAPN1 protein] which results in increased degradation of CAPN1 protein]
calpain inhibitor III inhibits the reaction [Calcium results in increased activity of CAPN1 protein]
CTD PMID:19490937 PMID:21516125 PMID:21985864 PMID:31398423 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
JBrowse link
G Car4 carbonic anhydrase 4 affects expression EXP Calcium affects the expression of CA4 mRNA CTD PMID:15913539 NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501
JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO
[Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in increased expression of CASP3 mRNA]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in increased expression of CASP3 mRNA]; Calcium affects the reaction [sodium arsenite results in increased expression of CASP3 mRNA]
Calcium deficiency inhibits the reaction [Dasatinib results in increased activity of CASP3 protein]; Calcium deficiency inhibits the reaction [Ionomycin results in increased activity of CASP3 protein]
CTD PMID:24184500 PMID:29803841 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 multiple interactions EXP [Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in increased expression of CASP9 mRNA]]; Calcium affects the reaction [sodium arsenite results in increased expression of CASP9 mRNA] CTD PMID:24184500 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Casr calcium-sensing receptor increases phosphorylation
multiple interactions
increases uptake
increases activity
affects expression
decreases response to substance
increases response to substance
ISO
EXP
Calcium results in increased phosphorylation of CASR protein
[Aluminum binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Calcium binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Calcium binds to and results in increased activity of CASR protein] which results in increased abundance of Inositol Phosphates; [Gadolinium binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Magnesium binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Neomycin binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; Calcium binds to and results in increased activity of CASR protein; Gadolinium inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]
CASR protein results in increased uptake of Calcium
Calcium results in increased activity of CASR protein
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [CASR protein results in increased uptake of Calcium]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [CASR protein results in increased uptake of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]; 2-aminoethoxydiphenyl borate inhibits the reaction [CASR protein results in increased uptake of Calcium]; [2-quinoxaline-carboxamide-N-adamantan-1-yl binds to and results in decreased activity of CASR protein] inhibits the reaction [Nickel results in increased abundance of Calcium]; [Calcium binds to and results in increased activity of CASR protein] which results in increased uptake of Calcium; [CASR protein mutant form results in increased susceptibility to Calcium] which results in increased abundance of Inositol 1,4,5-Trisphosphate; [Spermine binds to and results in increased activity of CASR protein] which results in increased uptake of Calcium; bisindolylmaleimide I inhibits the reaction [NPS R-467 promotes the reaction [Calcium results in increased phosphorylation of CASR protein]]; Calcium Chloride promotes the reaction [Calcium results in increased phosphorylation of CASR protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of WNT5A protein]; CASR protein affects the reaction [Nickel results in increased abundance of Calcium]; CASR protein promotes the reaction [TRPC6 protein results in increased uptake of Calcium]; chelerythrine inhibits the reaction [CASR protein results in increased uptake of Calcium]; Flufenamic Acid promotes the reaction [CASR protein results in increased uptake of Calcium]; Lanthanum inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]; Lanthanum inhibits the reaction [CASR protein results in increased uptake of Calcium]; methyl-beta-cyclodextrin inhibits the reaction [CASR protein results in increased uptake of Calcium]; N-(2-chlorophenylpropyl)-1-(3-methoxyphenyl)ethylamine affects the reaction [CASR gene mutant form results in increased susceptibility to Calcium]; N-(2-chlorophenylpropyl)-1-(3-methoxyphenyl)ethylamine promotes the reaction [CASR protein results in increased susceptibility to Calcium]; NPS R-467 promotes the reaction [Calcium results in increased phosphorylation of CASR protein]; Pertussis Toxin inhibits the reaction [CASR protein results in increased uptake of Calcium]
Calcium affects the expression of CASR mRNA; Calcium affects the expression of CASR protein
CASR protein mutant form results in decreased susceptibility to Calcium
CASR gene mutant form results in increased susceptibility to Calcium; CASR protein mutant form results in increased susceptibility to Calcium
CTD PMID:7874174 PMID:9011580 PMID:10231437 PMID:11071898 PMID:11089548 More... NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811
JBrowse link
G Cat catalase multiple interactions ISO
EXP
CAT protein inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; CAT protein inhibits the reaction [Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]]
[Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in decreased activity of CAT protein]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in decreased activity of CAT protein]; [Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of CAT protein]; Calcium affects the reaction [sodium arsenite results in decreased activity of CAT protein]
CTD PMID:21127073 PMID:22534743 PMID:24184500 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav1 caveolin 1 affects transport ISO CAV1 protein affects the transport of Calcium CTD PMID:16428350 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cav3 caveolin 3 multiple interactions ISO CAV3 protein affects the reaction [Potassium Chloride results in increased uptake of Calcium] CTD PMID:21294223 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
JBrowse link
G Cbfb core-binding factor subunit beta affects expression EXP Calcium affects the expression of CBFB mRNA CTD PMID:15913539 NCBI chr19:33,049,162...33,092,752
Ensembl chr19:33,049,172...33,092,751
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases uptake ISO CCL11 protein results in increased uptake of Calcium CTD PMID:10984371 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccl12 C-C motif chemokine ligand 12 increases uptake ISO CCL13 protein results in increased uptake of Calcium CTD PMID:10984371 NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases abundance
multiple interactions
increases uptake
ISO CCL2 protein results in increased abundance of Calcium
montelukast inhibits the reaction [CCL2 protein results in increased abundance of Calcium]; Piperidines analog inhibits the reaction [CCL2 protein results in increased uptake of Calcium]; resveratrol inhibits the reaction [CCL2 protein affects the localization of Calcium]
CTD PMID:10843593 PMID:10984371 PMID:16212921 PMID:16771778 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO resveratrol inhibits the reaction [CCL3 protein affects the localization of Calcium] CTD PMID:16212921 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases uptake ISO CCL5 protein results in increased uptake of Calcium CTD PMID:10984371 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases uptake
multiple interactions
ISO CCL7 protein results in increased uptake of Calcium
Piperidines analog inhibits the reaction [CCL7 protein results in increased uptake of Calcium]
CTD PMID:10843593 PMID:10984371 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Ccnd1 cyclin D1 affects expression
increases expression
EXP
ISO
Calcium affects the expression of CCND1 mRNA
Calcium results in increased expression of CCND1 mRNA
CTD PMID:15913539 PMID:24658506 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccr10 C-C motif chemokine receptor 10 affects abundance ISO CCR10 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr10:86,108,551...86,110,988
Ensembl chr10:86,108,551...86,110,988
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 affects abundance ISO CCR4 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr 8:114,176,256...114,182,155
Ensembl chr 8:114,176,974...114,178,056
JBrowse link
G Ccr8 C-C motif chemokine receptor 8 affects abundance ISO CCR8 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr 8:119,826,332...119,828,292
Ensembl chr 8:119,826,568...119,827,629
JBrowse link
G Ccr9 C-C motif chemokine receptor 9 affects abundance ISO CCR9 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr 8:123,396,157...123,410,199
Ensembl chr 8:123,395,813...123,413,969
JBrowse link
G Cd28 Cd28 molecule multiple interactions
increases abundance
ISO 1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [CD28 protein results in increased abundance of Calcium]; 2-aminoethoxydiphenylborane inhibits the reaction [CD28 protein results in increased abundance of Calcium]; 5-diisopropoxyphosphoryl-5-methyl-1-pyrroline-N-oxide inhibits the reaction [CD28 protein results in increased abundance of Calcium]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [CD28 protein results in increased abundance of Calcium] CTD PMID:14607919 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
JBrowse link
G Cd38 CD38 molecule multiple interactions ISO CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]; CD38 protein inhibits the reaction [CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]] CTD PMID:20200208 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986
JBrowse link
G Cdc42 cell division cycle 42 multiple interactions ISO Calcium promotes the reaction [PAFAH1B1 protein binds to IQGAP1 protein binds to CDC42 protein] CTD PMID:16369480 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Cdc42bpb CDC42 binding protein kinase beta affects expression EXP Calcium affects the expression of CDC42BPB mRNA CTD PMID:15913539 NCBI chr 6:130,333,712...130,416,631
Ensembl chr 6:130,333,712...130,416,377
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 increases cleavage
multiple interactions
ISO Calcium results in increased cleavage of CDK5R1 protein
calpeptin inhibits the reaction [Calcium results in increased cleavage of CDK5R1 protein]
CTD PMID:18242949 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta affects expression EXP Calcium affects the expression of CEBPB mRNA CTD PMID:15913539 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cerk ceramide kinase multiple interactions ISO Calcium affects the reaction [CERK protein results in increased phosphorylation of Ceramides] CTD PMID:16269826 NCBI chr 7:117,225,855...117,269,436
Ensembl chr 7:117,225,855...117,268,759
JBrowse link
G Cfb complement factor B multiple interactions ISO CFD protein affects the reaction [[cobra venom factor co-treated with Magnesium co-treated with Calcium] results in increased cleavage of CFB protein] CTD PMID:11724962 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
JBrowse link
G Cfd complement factor D multiple interactions ISO CFD protein affects the reaction [[cobra venom factor co-treated with Magnesium co-treated with Calcium] results in increased cleavage of CFB protein] CTD PMID:11724962 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
JBrowse link
G Cfl1 cofilin 1 multiple interactions ISO [Capsaicin results in decreased phosphorylation of and results in increased activity of CFL1 protein] which results in increased import of Calcium CTD PMID:17303079 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 multiple interactions ISO
EXP
[Acetylcholine results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; [Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; [Pilocarpine results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; CHRM1 protein promotes the reaction [Methacholine Compounds results in increased abundance of Calcium]
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; 1-oleoyl-2-acetylglycerol promotes the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; [Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; Atropine inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Flufenamic Acid inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Gadolinium inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Lanthanum inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Pirenzepine inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Thapsigargin inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]
[[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; [[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein
CTD PMID:11527950 PMID:11553362 PMID:12456425 PMID:18316702 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP [CHRNA4 protein co-treated with CHRNB2 protein mutant form] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein co-treated with CHRNB2 protein] affects the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein mutant form co-treated with CHRNB2 protein] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine] CTD PMID:12754307 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit multiple interactions ISO
EXP
[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium; [[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] which results in increased uptake of Calcium] inhibits the reaction [CHRNA7 protein results in decreased susceptibility to Okadaic Acid]; [Acetylcholine results in increased activity of CHRNA7 protein] which results in increased uptake of Calcium; [Bungarotoxins binds to and results in increased activity of CHRNA7 protein] which results in increased transport of Calcium; [methyllycaconitine binds to and results in increased activity of CHRNA7 protein] which results in increased transport of Calcium; [Nicotine results in increased activity of CHRNA7 protein] which results in increased transport of Calcium; [PNU-282987 binds to and results in increased activity of CHRNA7 protein] which results in increased uptake of Calcium; Bungarotoxins inhibits the reaction [[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium]; Mecamylamine inhibits the reaction [[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium]; methyllycaconitine inhibits the reaction [[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium]; methyllycaconitine promotes the reaction [[Nicotine results in increased activity of CHRNA7 protein] which results in increased transport of Calcium] CTD PMID:17709503 PMID:21051662 PMID:21715663 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO
EXP
[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium; alpha-conotoxin MII inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium]; Calcium affects the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased susceptibility to Okadaic Acid]; Dihydro-beta-Erythroidine inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium]; Mecamylamine inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium]
[CHRNA4 protein co-treated with CHRNB2 protein mutant form] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein co-treated with CHRNB2 protein] affects the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein mutant form co-treated with CHRNB2 protein] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine]
CTD PMID:12754307 PMID:21715663 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 affects expression EXP Calcium affects the expression of CITED2 mRNA CTD PMID:15913539 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
JBrowse link
G Cln8 CLN8, transmembrane ER and ERGIC protein multiple interactions ISO CLN8 protein affects the reaction [[Ionomycin co-treated with Calcium] results in increased transport of D-Aspartic Acid]; CLN8 protein affects the reaction [[Potassium Chloride co-treated with Calcium] results in increased transport of D-Aspartic Acid] CTD PMID:22302580 NCBI chr16:74,749,662...74,759,553
Ensembl chr16:74,749,662...74,759,774
JBrowse link
G Cnnm4 cyclin and CBS domain divalent metal cation transport mediator 4 affects expression EXP Calcium affects the expression of CNNM4 mRNA CTD PMID:15913539 NCBI chr 9:38,711,726...38,750,942
Ensembl chr 9:38,711,710...38,750,942
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions EXP [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein] affects the reaction [Potassium Chloride results in increased transport of Calcium]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] affects the reaction [Potassium Chloride results in increased transport of Calcium]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium results in increased transport of Calcium]; Calcium affects the reaction [Potassium Chloride results in decreased expression of CNR1 mRNA]; Calcium affects the reaction [Potassium Chloride results in decreased expression of CNR1 protein]; CNR1 protein affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; CNR1 protein affects the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Pertussis Toxin inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]] CTD PMID:12421626 PMID:14973253 PMID:16412482 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions ISO CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]; Pertussis Toxin inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]]; SR 144528 inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]] CTD PMID:10617657 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain affects abundance ISO COL18A1 protein affects the abundance of Calcium CTD PMID:15296943 NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593
JBrowse link
G Col1a2 collagen type I alpha 2 chain affects abundance ISO COL1A2 protein affects the abundance of Calcium CTD PMID:10913914 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Cp ceruloplasmin affects binding
multiple interactions
ISO
EXP
Calcium binds to CP protein
[Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of CP protein]
CTD PMID:17242517 PMID:22534743 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects expression
multiple interactions
EXP Calcium affects the expression of CREB1 mRNA
[Estradiol results in increased import of Calcium] which results in increased activity of CREB1 protein; Calcium promotes the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased phosphorylation of CREB1 protein]; Calcium promotes the reaction [Dopamine results in increased phosphorylation of CREB1 protein]
CTD PMID:14622123 PMID:15802184 PMID:15913539 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 affects expression EXP Calcium affects the expression of CSNK1A1 mRNA CTD PMID:15913539 NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271
JBrowse link
G Csnk1g3 casein kinase 1, gamma 3 affects expression EXP Calcium affects the expression of CSNK1G3 mRNA CTD PMID:15913539 NCBI chr18:47,287,466...47,386,538
Ensembl chr18:47,299,579...47,386,535
JBrowse link
G Ctnnb1 catenin beta 1 increases expression
multiple interactions
ISO Calcium results in increased expression of CTNNB1 mRNA; Calcium results in increased expression of CTNNB1 protein
CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]
CTD PMID:24658506 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctss cathepsin S multiple interactions ISO [CTSS protein results in increased cleavage of and results in decreased activity of CXCL10 protein] which results in decreased uptake of Calcium; [CTSS protein results in increased cleavage of and results in decreased activity of CXCL9 protein] which results in decreased uptake of Calcium; [CTSS protein results in increased cleavage of and results in increased activity of CXCL2 protein] which results in increased uptake of Calcium; [CTSS protein results in increased cleavage of and results in increased activity of CXCL5 protein] which results in increased uptake of Calcium CTD PMID:25833952 NCBI chr 2:183,089,192...183,114,483
Ensembl chr 2:183,086,437...183,114,483
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases abundance
multiple interactions
EXP CXCL1 protein results in increased abundance of Calcium
epigallocatechin gallate inhibits the reaction [CXCL1 protein results in increased abundance of Calcium]
CTD PMID:9430702 PMID:15237969 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO [CTSS protein results in increased cleavage of and results in decreased activity of CXCL10 protein] which results in decreased uptake of Calcium; [CXCL10 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium CTD PMID:25833952 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions
increases uptake
ISO resveratrol inhibits the reaction [CXCL12 protein affects the localization of Calcium]
CXCL12 protein results in increased uptake of Calcium
CTD PMID:10984371 PMID:11872090 PMID:16212921 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO [CTSS protein results in increased cleavage of and results in increased activity of CXCL2 protein] which results in increased uptake of Calcium; [CXCL2 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium CTD PMID:25833952 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 multiple interactions
increases abundance
ISO [[CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium] which results in increased expression of EGR1 mRNA; [CTSS protein results in increased cleavage of and results in decreased activity of CXCL9 protein] which results in decreased uptake of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium
CXCL9 protein results in increased abundance of Calcium
CTD PMID:12517959 PMID:25833952 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 multiple interactions
affects abundance
ISO [CXCL8 protein binds to and results in increased activity of CXCR1 protein] which results in increased abundance of and results in increased activity of Calcium
CXCR1 protein affects the abundance of Calcium
CTD PMID:11298490 PMID:12055238 NCBI chr 9:75,768,124...75,771,122
Ensembl chr 9:75,766,770...75,771,084
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 affects transport
multiple interactions
ISO CXCR2 protein affects the transport of Calcium
[CXCL2 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium; [CXCL5 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium; [CXCL8 protein binds to and results in increased activity of CXCR2 protein] which results in increased abundance of and results in increased activity of Calcium
Excitatory Amino Acid Agonists inhibits the reaction [CXCR2 protein affects the localization of Calcium]
CTD PMID:11298490 PMID:15618463 PMID:15914698 PMID:25833952 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 affects abundance
multiple interactions
ISO CXCR3 protein affects the abundance of Calcium
[[CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium] which results in increased expression of EGR1 mRNA; [CXCL10 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium
CTD PMID:12055238 PMID:12517959 PMID:25833952 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 affects abundance ISO CXCR4 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 affects abundance ISO CXCR5 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893
JBrowse link
G Cycs cytochrome c, somatic multiple interactions
increases secretion
decreases secretion
EXP [Calcium co-treated with Phosphates] affects the localization of CYCS protein; caffeic acid phenethyl ester inhibits the reaction [Calcium results in increased secretion of CYCS protein]; Cyclosporine inhibits the reaction [[Calcium co-treated with Phosphates] affects the localization of CYCS protein]; Nicotine inhibits the reaction [[Calcium co-treated with Phosphates] affects the localization of CYCS protein]; xestospongin C inhibits the reaction [Calcium results in decreased secretion of CYCS protein] CTD PMID:15345483 PMID:15469948 PMID:15985439 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO
EXP
2-aminoethoxydiphenyl borate inhibits the reaction [[oltipraz results in increased abundance of Calcium] which results in increased expression of CYP1A1 mRNA]; [2,3,7,8-tetrachlorodibenzofuran co-treated with Calcium] results in increased expression of CYP1A1 mRNA; [oltipraz results in increased abundance of Calcium] which results in increased expression of CYP1A1 mRNA; Calcium promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; Calcium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]
CTD PMID:1979076 PMID:11959854 PMID:16237193 PMID:23298284 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO Calcium promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; Calcium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
CTD PMID:16237193 PMID:19782052 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 affects expression
multiple interactions
EXP Calcium affects the expression of CYP24A1 mRNA
[Calcium co-treated with Calcitriol] affects the expression of CYP24A1 mRNA
CTD PMID:15913539 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 affects expression EXP Calcium affects the expression of CYP27B1 mRNA CTD PMID:15913539 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects expression
decreases uptake
EXP
ISO
Calcium affects the expression of CYP2E1 mRNA
CYP2E1 protein results in decreased uptake of Calcium
CTD PMID:15913539 PMID:19028543 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 multiple interactions ISO [CP 199330 binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; [CP 199331 binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; [CP 265298 binds to and results in decreased activity of CYSLTR1 protein] which results in decreased abundance of Calcium; [CP 288886 binds to and results in decreased activity of CYSLTR1 protein] which results in decreased abundance of Calcium; [Leukotriene C4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [Leukotriene D4 results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [Leukotriene E4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [pranlukast binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; [Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [zafirlukast binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; BAY u9773 inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; CYSLTR1 protein promotes the reaction [Leukotriene D4 results in increased abundance of Calcium]; montelukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; montelukast inhibits the reaction [[Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; pobilukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; pranlukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; verlukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; zafirlukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; zafirlukast inhibits the reaction [[Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; zafirlukast inhibits the reaction [CYSLTR1 protein promotes the reaction [Leukotriene D4 results in increased abundance of Calcium]] CTD PMID:8014876 PMID:9934474 PMID:10391245 PMID:10462554 PMID:10509933 More... NCBI chr  X:71,661,415...71,690,158
Ensembl chr  X:71,663,821...71,690,121
JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 multiple interactions ISO [Leukotriene C4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene C4 results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene D4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene D4 results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene E4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene E4 results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; BAY u9773 inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium] CTD PMID:10851239 PMID:11093801 NCBI chr15:48,190,251...48,229,906
Ensembl chr15:48,189,073...48,304,136
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 affects expression EXP Calcium affects the expression of DDR1 mRNA CTD PMID:15913539 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
JBrowse link
G Dmd dystrophin increases abundance
multiple interactions
ISO DMD gene mutant form results in increased abundance of Calcium
Nifedipine inhibits the reaction [DMD gene mutant form results in increased abundance of Calcium]
CTD PMID:24349043 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207
JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 multiple interactions
decreases transport
ISO [DNAJB11 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [DNAJB11 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin; DNAJB11 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium] CTD PMID:26085089 NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 multiple interactions
decreases transport
ISO [DNAJC3 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [DNAJC3 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin; DNAJC3 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium] CTD PMID:26085089 NCBI chr15:96,025,729...96,065,114
Ensembl chr15:96,025,624...96,065,181
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions EXP [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased activity of DRD1 protein] which results in increased abundance of Calcium CTD PMID:14622123 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions ISO
EXP
[Norepinephrine binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium; [Quinpirole binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium; Sulpiride inhibits the reaction [[Norepinephrine binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium]; Sulpiride inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium]
[DRD2 protein affects the abundance of Calcium] which results in decreased transport of Barium
CTD PMID:8032591 PMID:11124974 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Drd3 dopamine receptor D3 increases phosphorylation EXP Calcium results in increased phosphorylation of DRD3 protein CTD PMID:19217379 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions EXP Calcium affects the reaction [Potassium Chloride results in increased expression of DUSP1 mRNA] CTD PMID:11577072 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Edn1 endothelin 1 increases abundance
increases uptake
multiple interactions
affects transport
affects localization
EXP
ISO
EDN1 protein results in increased abundance of Calcium
EDN1 protein results in increased uptake of Calcium
EDN1 protein affects the localization of and affects the abundance of Calcium
Carvedilol inhibits the reaction [EDN1 protein results in increased import of and results in increased abundance of Calcium]; EDN1 protein affects the abundance of and affects the localization of Calcium; EDN1 protein results in increased import of and results in increased abundance of Calcium; Glucose affects the reaction [EDN1 protein affects the abundance of and affects the localization of Calcium]; Heparin inhibits the reaction [EDN1 protein results in increased abundance of Calcium]
EDN1 protein affects the transport of Calcium
EDN1 protein results in increased transport of and results in increased abundance of Calcium; Propofol inhibits the reaction [EDN1 protein affects the transport of Calcium]
EDN1 protein affects the localization of Calcium
CTD PMID:1443220 PMID:9138053 PMID:11425647 PMID:12628492 PMID:12821678 More... NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Edn2 endothelin 2 increases uptake
multiple interactions
ISO EDN2 protein results in increased uptake of Calcium
EDN2 protein affects the localization of and affects the abundance of Calcium
CTD PMID:11425647 NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814
JBrowse link
G Edn3 endothelin 3 multiple interactions
increases uptake
ISO
EXP
EDN3 protein affects the localization of and affects the abundance of Calcium
BQ 788 inhibits the reaction [EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium]]; EDN3 protein inhibits the reaction [APP protein results in increased uptake of Calcium]; EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium]
EDN3 protein results in increased uptake of Calcium
CTD PMID:11425647 PMID:12383957 PMID:15695168 NCBI chr 3:163,562,307...163,586,636
Ensembl chr 3:163,562,520...163,585,093
JBrowse link
G Ednra endothelin receptor type A affects activity EXP Calcium affects the activity of EDNRA protein CTD PMID:12628492 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of EEF2 mRNA CTD PMID:15913539 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
JBrowse link
G Egf epidermal growth factor increases abundance
multiple interactions
increases transport
affects expression
ISO
EXP
EGF protein results in increased abundance of Calcium
[IGF2 protein co-treated with EGF protein] results in increased import of Calcium
EGF protein results in increased transport of Calcium
[Calcium co-treated with Calcitriol] affects the expression of EGF mRNA
RTKI cpd inhibits the reaction [EGF protein results in increased abundance of Calcium]
Calcium affects the expression of EGF mRNA
CTD PMID:2442157 PMID:11527950 PMID:15913539 PMID:24990931 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions EXP Calcium affects the phosphorylation of and affects the expression of EGFR protein CTD PMID:8393775 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO [[CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium] which results in increased expression of EGR1 mRNA; [Ionomycin results in increased abundance of Calcium] which results in increased expression of EGR1 protein CTD PMID:12517959 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions ISO Calcium promotes the reaction [Diclofenac results in increased phosphorylation of EIF2AK3 protein] CTD PMID:26609140 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of EIF4A2 mRNA CTD PMID:15913539 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions EXP Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:12935885 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Ephx2 epoxide hydrolase 2 affects expression EXP Calcium affects the expression of EPHX2 mRNA CTD PMID:15913539 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G F2 coagulation factor II increases abundance
increases localization
multiple interactions
increases uptake
ISO F2 protein results in increased abundance of Calcium
F2 protein results in increased localization of Calcium
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [F2 protein results in increased localization of Calcium]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [F2 protein results in increased localization of Calcium]; Apigenin inhibits the reaction [F2 protein results in increased localization of Calcium]; arsenite inhibits the reaction [F2 protein results in increased abundance of Calcium]; Genistein inhibits the reaction [F2 protein results in increased localization of Calcium]; Nickel inhibits the reaction [F2 protein results in increased uptake of Calcium]; Quercetin inhibits the reaction [F2 protein results in increased localization of Calcium]
CTD PMID:2125206 PMID:19814731 PMID:22244921 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F2r coagulation factor II (thrombin) receptor multiple interactions ISO [Peptides results in increased activity of F2R protein] which results in increased abundance of Calcium CTD PMID:15086339 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions ISO F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]; PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]] CTD PMID:16793902 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 multiple interactions ISO F2RL3 protein affects the localization of and affects the transport of Calcium
[alanyl-tyrosyl-prolyl-glycyl-lysyl-phenylalanine binds to and results in increased activity of F2RL3 protein] which results in increased uptake of Calcium
CTD PMID:16702038 PMID:17707436 NCBI chr16:17,117,441...17,119,434
Ensembl chr16:17,117,441...17,119,472
JBrowse link
G F8 coagulation factor VIII multiple interactions ISO [Copper co-treated with Calcium] results in increased activity of [F8 protein alternative form binds to F8 protein alternative form]; Calcium results in increased activity of [F8 protein alternative form binds to F8 protein alternative form] CTD PMID:11513607 NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857
JBrowse link
G Faslg Fas ligand multiple interactions
affects localization
ISO bafilomycin A1 inhibits the reaction [FASL protein affects the localization of Calcium]; CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]; CD38 protein inhibits the reaction [CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]]; Ryanodine inhibits the reaction [FASL protein affects the localization of Calcium] CTD PMID:20200208 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression EXP Calcium results in increased expression of FGF1 protein CTD PMID:15264218 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Fgf23 fibroblast growth factor 23 affects expression ISO Calcium affects the expression of FGF23 mRNA; Calcium affects the expression of FGF23 protein CTD PMID:15086938 PMID:16381997 NCBI chr 4:159,914,393...159,922,073
Ensembl chr 4:159,914,272...159,923,821
JBrowse link
G Fgf9 fibroblast growth factor 9 affects expression EXP Calcium affects the expression of FGF9 mRNA CTD PMID:15913539 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of FGFR1 mRNA CTD PMID:15913539 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Fis1 fission, mitochondrial 1 affects expression EXP Calcium affects the expression of FIS1 mRNA CTD PMID:15913539 NCBI chr12:19,708,558...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A multiple interactions ISO FKBP1A protein inhibits the reaction [Calcium results in increased activity of RYR2 protein] CTD PMID:17872463 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B multiple interactions ISO FKBP1B gene mutant form inhibits the reaction [Acetylcholine affects the localization of and affects the abundance of Calcium]; Ryanodine inhibits the reaction [FKBP1B gene mutant form inhibits the reaction [Acetylcholine affects the localization of and affects the abundance of Calcium]] CTD PMID:17261647 NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653
JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) affects expression EXP Calcium affects the expression of FURIN mRNA CTD PMID:15913539 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314
JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 multiple interactions
decreases activity
ISO Calcium inhibits the reaction [FXYD2 protein results in increased transport of Deoxyglucose]; Calcium inhibits the reaction [FXYD2 protein results in increased transport of Inulin]
Calcium results in decreased activity of FXYD2 protein
CTD PMID:11533133 NCBI chr 8:45,712,887...45,720,032
Ensembl chr 8:45,712,903...45,720,203
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 affects expression EXP Calcium affects the expression of G6PC1 mRNA CTD PMID:15913539 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 multiple interactions
affects expression
ISO
EXP
Calcium promotes the reaction [3-aminopropylphosphinic acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]; Calcium promotes the reaction [CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]]; Calcium promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]
Calcium affects the expression of GABBR1 mRNA
CTD PMID:15627515 PMID:15913539 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 multiple interactions ISO Calcium promotes the reaction [3-aminopropylphosphinic acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]; Calcium promotes the reaction [CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]]; Calcium promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]] CTD PMID:15627515 NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104
JBrowse link
G Gast gastrin multiple interactions ISO Calcium promotes the reaction [Colforsin results in increased secretion of GAST protein]; Calcium promotes the reaction [Terbutaline results in increased secretion of GAST protein] CTD PMID:9277405 NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496
JBrowse link
G Gata1 GATA binding protein 1 affects expression EXP Calcium affects the expression of GATA1 mRNA CTD PMID:15913539 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530
JBrowse link
G Gc GC, vitamin D binding protein affects expression EXP Calcium affects the expression of GC mRNA CTD PMID:15913539 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
JBrowse link
G Gcg glucagon multiple interactions EXP Calcium affects the reaction [Pyruvic Acid results in increased secretion of GCG protein] CTD PMID:15919803 NCBI chr 3:47,113,914...47,122,929
Ensembl chr 3:47,113,914...47,122,929
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of GCLC mRNA CTD PMID:15913539 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions EXP Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]; Calcium deficiency inhibits the reaction [Ethanol results in increased expression of GFAP protein] CTD PMID:17888892 PMID:21879721 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Ghr growth hormone receptor affects expression
multiple interactions
EXP Calcium affects the expression of GHR mRNA
[Calcium co-treated with Calcitriol] affects the expression of GHR mRNA
CTD PMID:15913539 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735
JBrowse link
G Gipc3 GIPC PDZ domain containing family, member 3 affects uptake ISO GIPC3 protein affects the uptake of Calcium CTD PMID:27462107 NCBI chr 7:8,374,941...8,383,281 JBrowse link
G Glrx3 glutaredoxin 3 affects response to substance EXP GLRX3 protein affects the susceptibility to Calcium CTD PMID:16809552 NCBI chr 1:192,241,707...192,272,012
Ensembl chr 1:192,241,701...192,272,010
JBrowse link
G Gnai2 G protein subunit alpha i2 affects expression EXP Calcium affects the expression of GNAI2 mRNA CTD PMID:15913539 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
JBrowse link
G Gnas GNAS complex locus multiple interactions ISO [[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium; [[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium CTD PMID:23022524 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262
JBrowse link
G Gpbar1 G protein-coupled bile acid receptor 1 multiple interactions ISO [Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased abundance of Calcium
[[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium; [[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium
CTD PMID:23022524 NCBI chr 9:75,862,151...75,863,140
Ensembl chr 9:75,860,677...75,863,168
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 multiple interactions EXP Calcium deficiency inhibits the reaction [Excitatory Amino Acid Agonists results in decreased phosphorylation of GRIA1 protein] CTD PMID:28404816 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 multiple interactions EXP Calcium promotes the reaction [PICK1 protein binds to GRIA2 protein] CTD PMID:28404816 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
JBrowse link
G Grm1 glutamate metabotropic receptor 1 multiple interactions EXP 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]; [3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium; Flufenamic Acid inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]; GRM1 protein promotes the reaction [Propionates results in increased transport of Calcium]; Ruthenium Red inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium] CTD PMID:14622174 PMID:24582715 NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP [Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in decreased activity of GSR protein]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in decreased activity of GSR protein]; [Carmustine results in decreased activity of GSR protein] which results in increased uptake of Calcium; Calcium affects the reaction [sodium arsenite results in decreased activity of GSR protein] CTD PMID:15321730 PMID:24184500 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Hcar2 hydroxycarboxylic acid receptor 2 multiple interactions ISO [Nicotinic Acids results in increased activity of HCAR2 protein] which results in increased abundance of Calcium CTD PMID:17008386 NCBI chr12:32,726,334...32,727,416
Ensembl chr12:32,726,184...32,728,504
JBrowse link
G Hectd4 HECT domain E3 ubiquitin protein ligase 4 multiple interactions ISO Calcium affects the reaction [HECTD4 gene SNP affects the abundance of Lead] CTD PMID:28212632 NCBI chr12:35,182,165...35,330,935
Ensembl chr12:35,182,154...35,330,987
JBrowse link
G Hes1 hes family bHLH transcription factor 1 affects expression EXP Calcium affects the expression of HES1 mRNA CTD PMID:15913539 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hgf hepatocyte growth factor increases abundance EXP HGF protein results in increased abundance of Calcium CTD PMID:10963052 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 affects expression EXP Calcium affects the expression of HMGCS2 mRNA CTD PMID:15913539 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO Calcium affects the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA] CTD PMID:21443188 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha affects expression EXP Calcium affects the expression of HNF4A mRNA CTD PMID:15913539 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D multiple interactions EXP Calcium deficiency promotes the reaction [HNRNPD protein binds to PTH 3' UTR] CTD PMID:18583400 NCBI chr14:9,615,375...9,638,975
Ensembl chr14:9,615,479...9,633,786
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U affects expression EXP Calcium affects the expression of SP120 mRNA CTD PMID:15913539 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588
JBrowse link
G Homer1 homer scaffold protein 1 multiple interactions EXP HOMER1 protein alternative form inhibits the reaction [Caffeine promotes the reaction [RYR2 protein results in increased secretion of Calcium]]; HOMER1 protein alternative form inhibits the reaction [Cyclic ADP-Ribose promotes the reaction [RYR2 protein results in increased secretion of Calcium]] CTD PMID:12887973 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785
JBrowse link
G Hpca hippocalcin decreases response to substance ISO HPCA protein results in decreased susceptibility to Calcium CTD PMID:12445469 NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841
JBrowse link
G Hrh1 histamine receptor H 1 multiple interactions
increases abundance
ISO [6-((2-(4-imidazolyl)ethyl)amino)heptanoic acid 4-toluidide binds to and results in increased activity of HRH1 protein] which results in increased abundance of Calcium; [Histamine results in increased activity of HRH1 protein] which results in increased abundance of Calcium; [HRH1 protein binds to Histamine] which results in increased import of Calcium; [HRH1 protein binds to Lidocaine] which results in increased import of Calcium; [HRH1 protein binds to Procaine] which results in increased import of Calcium; [HRH1 protein binds to Tetracaine] which results in increased import of Calcium; fexofenadine inhibits the reaction [[Histamine binds to and results in increased activity of HRH1 protein] which results in increased abundance of Calcium]; HRH1 protein promotes the reaction [Histamine results in increased export of Calcium]; Triprolidine inhibits the reaction [[Histamine results in increased activity of HRH1 protein] which results in increased abundance of Calcium]; Triprolidine inhibits the reaction [HRH1 protein promotes the reaction [Histamine results in increased export of Calcium]]
HRH1 protein results in increased abundance of Calcium
CTD PMID:2419744 PMID:11238657 PMID:11527950 PMID:19443731 PMID:32061592 NCBI chr 4:147,564,781...147,649,353
Ensembl chr 4:147,645,995...147,647,455
JBrowse link
G Hrh3 histamine receptor H3 multiple interactions ISO [4-(1H-imidazol-4-ylmethyl)piperidine binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; [Histamine binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; [imetit binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; [Methylhistamines binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; clobenpropit inhibits the reaction [[Methylhistamines binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium] CTD PMID:12706455 NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642
JBrowse link
G Hrh4 histamine receptor H4 multiple interactions ISO 1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine inhibits the reaction [[4-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium]; 1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine inhibits the reaction [[clobenpropit binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium]; [4-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [alpha-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [clobenpropit binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [Histamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [imetit binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [N-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium CTD PMID:11181941 PMID:17507084 NCBI chr18:4,166,270...4,182,426
Ensembl chr18:4,166,270...4,246,345
JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of HSD17B12 mRNA CTD PMID:15913539 NCBI chr 3:79,990,048...80,113,556
Ensembl chr 3:79,990,056...80,113,617
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]] CTD PMID:23184943 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
decreases transport
ISO [DNAJB11 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [DNAJC3 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [HSPA5 protein binds to SEC61A1 protein] which results in decreased transport of Calcium; [HSPA5 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin CTD PMID:26085089 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 increases abundance EXP HSPA9 protein results in increased abundance of Calcium CTD PMID:34308505 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A increases activity ISO Calcium results in increased activity of HTR1A protein CTD PMID:11356925 NCBI chr 2:36,694,174...36,695,442
Ensembl chr 2:36,694,174...36,695,442
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions EXP HTR2A protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium] CTD PMID:16901936 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B multiple interactions ISO Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK1 protein]; Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK3 protein] CTD PMID:18758753 NCBI chr 9:86,735,793...86,756,640
Ensembl chr 9:86,742,102...86,755,108
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 multiple interactions EXP HTR7 protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium] CTD PMID:16901936 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626
JBrowse link
G Ifng interferon gamma multiple interactions ISO KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]]
[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]; [TNF protein co-treated with IFNG protein] promotes the reaction [Diclofenac affects the abundance of Calcium]; Calcium promotes the reaction [[Diclofenac co-treated with IFNG protein] results in increased phosphorylation of STAT1 protein]
CTD PMID:23747339 PMID:26609140 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ift88 intraflagellar transport 88 multiple interactions
increases uptake
ISO Gadolinium inhibits the reaction [IFT88 protein mutant form results in increased uptake of Calcium]; IFT88 protein affects the reaction [PKD2 protein results in increased uptake of Calcium] CTD PMID:16396941 NCBI chr15:31,573,325...31,666,068
Ensembl chr15:31,573,376...31,672,147
JBrowse link
G Igf1 insulin-like growth factor 1 affects expression
multiple interactions
increases import
EXP
ISO
Calcium affects the expression of IGF1 mRNA
Cobalt inhibits the reaction [IGF1 protein results in increased import of Calcium]; tetramethrin inhibits the reaction [IGF1 protein results in increased import of Calcium]
CTD PMID:1550224 PMID:2460452 PMID:2539779 PMID:15913539 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf2 insulin-like growth factor 2 multiple interactions
increases import
ISO [IGF2 protein co-treated with EGF protein] results in increased import of Calcium; Cobalt inhibits the reaction [IGF2 protein results in increased import of Calcium]; Lanthanum inhibits the reaction [IGF2 protein results in increased import of Calcium]; Pertussis Toxin inhibits the reaction [IGF2 protein results in increased import of Calcium]; tetramethrin inhibits the reaction [IGF2 protein results in increased import of Calcium] CTD PMID:2442157 PMID:2460452 PMID:2539779 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 affects expression EXP Calcium affects the expression of IGFBP2 mRNA CTD PMID:15913539 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 affects expression
decreases degradation
EXP Calcium affects the expression of IGFBP5 mRNA
Calcium results in decreased degradation of IGFBP5 protein
CTD PMID:8894652 PMID:15913539 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
JBrowse link
G Il11 interleukin 11 multiple interactions
increases abundance
ISO Flurbiprofen inhibits the reaction [IL11 protein results in increased abundance of Calcium]; IL13 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium]; IL4 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium]; IL6ST protein promotes the reaction [IL11 protein results in increased abundance of Calcium]; Indomethacin inhibits the reaction [IL11 protein results in increased abundance of Calcium]; TNFRSF11B protein inhibits the reaction [IL11 protein results in increased abundance of Calcium] CTD PMID:12110441 NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
JBrowse link
G Il13 interleukin 13 multiple interactions ISO IL13 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium] CTD PMID:12110441 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]] CTD PMID:23747339 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il4 interleukin 4 multiple interactions ISO IL4 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium] CTD PMID:12110441 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO Calcimycin inhibits the reaction [Calcium promotes the reaction [Histamine results in increased expression of IL6 protein]]; Calcium promotes the reaction [Histamine results in increased expression of IL6 protein]; Edetic Acid inhibits the reaction [Calcium promotes the reaction [Histamine results in increased expression of IL6 protein]]
Calcium results in increased expression of IL6 mRNA
CTD PMID:11238657 PMID:20682585 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6st interleukin 6 cytokine family signal transducer multiple interactions ISO IL6ST protein promotes the reaction [IL11 protein results in increased abundance of Calcium] CTD PMID:12110441 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936
JBrowse link
G Ilf3 interleukin enhancer binding factor 3 multiple interactions ISO Calcium affects the reaction [Vanadates results in increased activity of ILF3 protein] CTD PMID:10623810 NCBI chr 8:19,922,409...19,960,495
Ensembl chr 8:19,922,460...19,960,350
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 multiple interactions ISO Calcium promotes the reaction [PAFAH1B1 protein binds to IQGAP1 protein binds to CDC42 protein] CTD PMID:16369480 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
JBrowse link
G Itga2 integrin subunit alpha 2 multiple interactions ISO ITGA2 protein promotes the reaction [[Dinoprostone co-treated with Serotonin] results in increased import of Calcium]; TRPV4 protein promotes the reaction [ITGA2 protein promotes the reaction [[Dinoprostone co-treated with Serotonin] results in increased import of Calcium]] CTD PMID:18234883 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481
JBrowse link
G Itgb1bp2 integrin subunit beta 1 binding protein 2 multiple interactions ISO Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to SUGT1 protein]]
Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]]
CTD PMID:23184943 NCBI chr  X:66,572,537...66,577,174
Ensembl chr  X:66,572,537...66,577,174
JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 multiple interactions ISO Calcium promotes the reaction [ITIH1 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr16:6,122,246...6,136,363
Ensembl chr16:6,122,248...6,136,363
JBrowse link
G Itih2 inter-alpha-trypsin inhibitor heavy chain 2 multiple interactions ISO Calcium promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr17:68,375,518...68,411,849
Ensembl chr17:68,375,567...68,411,841
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 multiple interactions ISO ITPR1 protein promotes the reaction [Acetaldehyde metabolite results in increased abundance of Calcium]; ITPR1 protein promotes the reaction [Ethanol metabolite results in increased abundance of Calcium] CTD PMID:17241155 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 multiple interactions ISO 2-aminoethoxydiphenyl borate inhibits the reaction [[adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium]; [adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium; xestospongin C inhibits the reaction [[adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium] CTD PMID:15201137 NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164
JBrowse link
G Itpr3 inositol 1,4,5-trisphosphate receptor, type 3 affects expression EXP Calcium affects the expression of ITPR3 protein CTD PMID:10963052 NCBI chr20:5,136,968...5,202,339
Ensembl chr20:5,136,441...5,202,337
JBrowse link
G Ivl involucrin increases expression
multiple interactions
ISO Calcium results in increased expression of IVL mRNA
NPS R-467 promotes the reaction [Calcium results in increased expression of IVL mRNA]
CTD PMID:10469331 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO JAK2 protein promotes the reaction [LEP protein results in increased transport of Calcium] CTD PMID:20107083 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 increases activity
multiple interactions
ISO Calcium results in increased activity of KCNE1 protein
W 7 inhibits the reaction [Calcium results in increased activity of KCNE1 protein]
CTD PMID:1655403 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions EXP Nimodipine inhibits the reaction [KCNH2 protein affects the abundance of Calcium] CTD PMID:11040061 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 multiple interactions
affects abundance
ISO Dantrolene inhibits the reaction [KCNJ11 protein mutant form results in increased abundance of Calcium]; KCNJ11 protein affects the reaction [[Manganese co-treated with Dobutamine] results in increased abundance of Calcium]; W 7 inhibits the reaction [KCNJ11 protein mutant form results in increased abundance of Calcium]
KCNJ11 protein affects the abundance of Calcium
CTD PMID:17189350 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 multiple interactions
increases response to substance
ISO
EXP
[KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium; Lithocholic Acid promotes the reaction [[KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium]
KCNMA1 mRNA alternative form results in increased susceptibility to Calcium
CTD PMID:22123969 PMID:28090300 NCBI chr15:302,078...1,001,198
Ensembl chr15:302,214...1,001,198
JBrowse link
G Kcnmb1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 multiple interactions ISO [KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium; Lithocholic Acid promotes the reaction [[KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium] CTD PMID:22123969 NCBI chr10:18,557,510...18,614,824
Ensembl chr10:18,557,904...18,565,798
JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 increases activity
multiple interactions
ISO Calcium results in increased activity of KCNN2 protein
cyclohexyl-(2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl)amine promotes the reaction [Calcium results in increased activity of KCNN2 protein]
CTD PMID:17486140 NCBI chr18:37,817,966...38,258,347
Ensembl chr18:37,817,957...38,258,347
JBrowse link
G Kcnn3 potassium calcium-activated channel subfamily N member 3 multiple interactions
increases activity
ISO 6,7-dichloro-1H-indole-2,3-dione 3-oxime promotes the reaction [Calcium results in increased activity of KCNN3 protein]; cyclohexyl-(2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl)amine promotes the reaction [Calcium results in increased activity of KCNN3 protein] CTD PMID:17486140 NCBI chr 2:174,929,846...175,088,910
Ensembl chr 2:174,936,629...175,081,145
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 affects abundance
multiple interactions
ISO KCNN4 protein affects the abundance of Calcium
KCNN4 protein affects the reaction [Calcium results in increased transport of Potassium]
CTD PMID:11826162 PMID:14985237 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340
JBrowse link
G Kdr kinase insert domain receptor multiple interactions ISO [VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium; TRPC6 protein promotes the reaction [[VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium]
Calcium promotes the reaction [Corticosterone results in decreased expression of KDR protein]
CTD PMID:14551041 PMID:21647420 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Khsrp KH-type splicing regulatory protein multiple interactions EXP Calcium deficiency inhibits the reaction [KHSRP protein binds to PTH 3' UTR] CTD PMID:18583400 NCBI chr 9:1,862,555...1,872,301
Ensembl chr 9:1,862,899...1,872,451
JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor multiple interactions ISO 2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; [KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium; Flufenamic Acid inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin promotes the reaction [2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]] CTD PMID:18948403 NCBI chr13:44,774,823...44,780,707
Ensembl chr13:44,774,823...44,780,612
JBrowse link
G Kiss1r KISS1 receptor multiple interactions ISO 2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; [KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium; Flufenamic Acid inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin promotes the reaction [2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]] CTD PMID:18948403 NCBI chr 7:9,785,135...9,790,283
Ensembl chr 7:9,785,135...9,788,793
JBrowse link
G Kl Klotho affects abundance
multiple interactions
ISO KL protein affects the abundance of Calcium
KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]]
CTD PMID:11796525 PMID:23747339 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
JBrowse link
G Klk1 kallikrein 1 decreases activity ISO Calcium results in decreased activity of KLK1 protein CTD PMID:15558947 NCBI chr 1:94,642,722...94,646,714
Ensembl chr 1:94,642,687...94,646,754
JBrowse link
G Klk8 kallikrein related-peptidase 8 increases activity ISO Calcium results in increased activity of KLK8 protein CTD PMID:16800733 NCBI chr 1:94,251,803...94,258,646
Ensembl chr 1:94,251,803...94,258,646
JBrowse link
G Kng2 kininogen 2 multiple interactions
increases abundance
affects abundance
ISO
EXP
BDKRB2 protein affects the reaction [KNG1 protein affects the abundance of Calcium]
KNG1 protein modified form results in increased abundance of Calcium
B 4162 inhibits the reaction [pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]]; BDKRB2 protein affects the reaction [pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]]; CALR protein promotes the reaction [KNG1 protein modified form results in increased abundance of Calcium]; KNG1 protein affects the transport of and affects the localization of Calcium; pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]
[KNG1 protein alternative form co-treated with Calcium] results in increased secretion of CALCA protein; Calcium affects the reaction [KNG1 protein results in increased secretion of Excitatory Amino Acid Agents]
KNG1 protein results in increased abundance of Calcium
CTD PMID:7961812 PMID:8592139 PMID:10535458 PMID:12582005 PMID:16473424 More... NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971
JBrowse link
G Krt1 keratin 1 multiple interactions
increases expression
ISO 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; 15-hydroxy-5,8,11,13-eicosatetraenoic acid inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; 8-hydroxyeicosatetraenoic acid promotes the reaction [Calcium results in increased expression of KRT1 mRNA]; Masoprocol inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; morin inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; Quercetin inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of KRT1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of KRT1 protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; SB 203580 inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; SB 203580 inhibits the reaction [Calcium results in increased expression of KRT1 protein]; WNT5A protein promotes the reaction [Calcium results in increased expression of KRT1 mRNA]; WNT5A protein promotes the reaction [Calcium results in increased expression of KRT1 protein]
Calcium results in increased expression of KRT1 mRNA; Calcium results in increased expression of KRT1 protein
CTD PMID:12069687 PMID:21524694 PMID:24658506 NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844
JBrowse link
G Lep leptin affects abundance
multiple interactions
affects secretion
increases transport
affects expression
decreases abundance
ISO
EXP
LEP protein affects the abundance of Calcium
Calcium deficiency inhibits the reaction [[Glucose co-treated with INS1 protein] results in increased secretion of LEP protein]
Calcium deficiency affects the secretion of LEP protein
LEP protein results in increased transport of Calcium
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [LEP protein results in increased transport of Calcium]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [LEP protein results in increased transport of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [LEP protein results in increased transport of Calcium]; acetovanillone inhibits the reaction [LEP protein affects the abundance of Calcium]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [LEP protein results in increased transport of Calcium]; BQ 788 inhibits the reaction [LEP protein affects the abundance of Calcium]; Calcium promotes the reaction [LEP protein results in increased transport of Calcium]; cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [LEP protein affects the abundance of Calcium]; edelfosine inhibits the reaction [LEP protein results in increased transport of Calcium]; Flufenamic Acid inhibits the reaction [LEP protein results in increased transport of Calcium]; JAK2 protein promotes the reaction [LEP protein results in increased transport of Calcium]; Lanthanum promotes the reaction [LEP protein results in increased transport of Calcium]; LEP protein promotes the reaction [TRPC1 protein results in increased transport of Calcium]; LEP protein promotes the reaction [TRPC4 protein results in increased transport of Calcium]; LEP protein promotes the reaction [TRPC5 protein results in increased transport of Calcium]; Wortmannin inhibits the reaction [LEP protein results in increased transport of Calcium]
Calcium affects the expression of LEP mRNA
LEP protein results in decreased abundance of Calcium
CTD PMID:10780946 PMID:14657008 PMID:15913539 PMID:16380530 PMID:20107083 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lepr leptin receptor affects expression EXP Calcium affects the expression of LEPR mRNA CTD PMID:15913539 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Lif LIF, interleukin 6 family cytokine increases abundance EXP LIF protein results in increased abundance of Calcium CTD PMID:11073891 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G LOC686683 similar to olfactory receptor 73 multiple interactions ISO [ethyl vanillin binds to and results in increased activity of OR5D18 protein] which results in increased transport of Calcium; [Eugenol binds to and results in increased activity of OR5D18 protein] which results in increased transport of Calcium; [Eugenol binds to OR5D18 protein] which results in increased transport of Calcium; [isomethyleugenol binds to and results in decreased activity of OR5D18 protein] which results in decreased transport of Calcium; isomethyleugenol inhibits the reaction [[Eugenol binds to OR5D18 protein] which results in increased transport of Calcium] CTD PMID:14685265 PMID:15716417 NCBI chr 3:73,516,522...73,517,463
Ensembl chr 3:73,516,364...73,519,858
Ensembl chr 3:73,516,364...73,519,858
JBrowse link
G Loricrin loricrin cornified envelope precursor protein increases expression
multiple interactions
ISO Calcium results in increased expression of LORICRIN mRNA; Calcium results in increased expression of LORICRIN protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of LORICRIN mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of LORICRIN protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; SB 203580 inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; SB 203580 inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; WNT5A protein promotes the reaction [Calcium results in increased expression of LORICRIN mRNA]; WNT5A protein promotes the reaction [Calcium results in increased expression of LORICRIN protein]
CTD PMID:21524694 PMID:24658506 NCBI chr 2:177,558,062...177,559,980
Ensembl chr 2:177,558,252...177,559,807
JBrowse link
G Lypla1 lysophospholipase 1 multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of LYPLA1 mRNA CTD PMID:15913539 NCBI chr 5:14,679,605...14,708,774
Ensembl chr 5:14,679,606...14,708,746
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions EXP [Sumatriptan results in increased abundance of Calcium] inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA]; Calcium inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA] CTD PMID:12574409 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 affects expression EXP Calcium affects the expression of MAP2K2 mRNA CTD PMID:15913539 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO
EXP
Calcium results in increased phosphorylation of MAPK1 protein
Calcium promotes the reaction [Diclofenac results in increased phosphorylation of MAPK1 protein]
Calcium affects the reaction [Ptychodiscus brevis T2 toxin affects the phosphorylation of MAPK1 protein]; Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK1 protein]
Calcium deficiency inhibits the reaction [Carbachol results in increased phosphorylation of and results in increased activity of MAPK1 protein]
CTD PMID:10660688 PMID:15086530 PMID:16877402 PMID:17537980 PMID:18758753 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 affects expression EXP Calcium affects the expression of MAPK14 mRNA CTD PMID:15913539 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO
EXP
Calcium results in increased phosphorylation of MAPK3 protein
Calcium promotes the reaction [Diclofenac results in increased phosphorylation of MAPK3 protein]
Calcium deficiency inhibits the reaction [Carbachol results in increased phosphorylation of and results in increased activity of MAPK3 protein]
Calcium affects the reaction [Ptychodiscus brevis T2 toxin affects the phosphorylation of MAPK3 protein]; Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]; Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK3 protein]
CTD PMID:10660688 PMID:15086530 PMID:16877402 PMID:17537980 PMID:18758753 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk4 mitogen-activated protein kinase 4 affects expression EXP Calcium affects the expression of MAPK4 mRNA CTD PMID:15913539 NCBI chr18:67,512,805...67,661,271
Ensembl chr18:67,512,807...67,661,842
JBrowse link
G Marco macrophage receptor with collagenous structure multiple interactions ISO Calcium promotes the reaction [titanium dioxide binds to MARCO protein] CTD PMID:18836211 NCBI chr13:31,616,278...31,648,521
Ensembl chr13:31,616,278...31,648,521
JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 multiple interactions ISO [NAADP results in increased activity of MCOLN1 protein] which affects the localization of Calcium CTD PMID:21613607 NCBI chr12:1,560,341...1,574,252
Ensembl chr12:1,560,359...1,574,252
JBrowse link
G Mcu mitochondrial calcium uniporter affects localization ISO MCU protein affects the localization of Calcium CTD PMID:22829870 NCBI chr20:27,417,529...27,580,110
Ensembl chr20:27,417,526...27,580,110
JBrowse link
G Mgp matrix Gla protein multiple interactions
affects expression
affects binding
ISO
EXP
[Calcium binds to MGP protein] which binds to and results in decreased activity of BMP4 protein; [Edetic Acid inhibits the reaction [Calcium binds to MGP protein]] inhibits the reaction [MGP protein binds to BMP4 protein]; Edetic Acid inhibits the reaction [Calcium binds to MGP protein]
Calcium affects the expression of MGP mRNA
CTD PMID:15913539 PMID:18369157 NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667
JBrowse link
G Mmp1 matrix metallopeptidase 1 affects expression ISO Calcium affects the expression of MMP1 mRNA; Calcium affects the expression of MMP1 protein CTD PMID:17508023 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions EXP Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of MTOR protein] CTD PMID:12935885 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Mybpc3 myosin binding protein C3 increases response to substance
multiple interactions
ISO MYBPC3 gene mutant form results in increased susceptibility to Calcium
epigallocatechin gallate inhibits the reaction [MYBPC3 gene mutant form results in increased susceptibility to Calcium]
CTD PMID:27994558 NCBI chr 3:77,095,165...77,113,406
Ensembl chr 3:77,095,252...77,113,405
JBrowse link
G Myh7 myosin heavy chain 7 increases transport ISO MYH7 gene mutant form results in increased transport of Calcium CTD PMID:29741611 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217
JBrowse link
G Myl2 myosin light chain 2 multiple interactions ISO Calcium affects the reaction [MYL2 gene SNP affects the abundance of Lead] CTD PMID:28212632 NCBI chr12:34,454,223...34,468,554
Ensembl chr12:34,454,218...34,468,983
JBrowse link
G Myl3 myosin light chain 3 affects expression EXP Calcium affects the expression of MYL3 mRNA CTD PMID:15913539 NCBI chr 8:110,738,669...110,744,814
Ensembl chr 8:110,738,661...110,744,816
JBrowse link
G Myl9 myosin light chain 9 multiple interactions
affects phosphorylation
decreases phosphorylation
EXP [[Calcium results in increased activity of MYLK protein] which results in increased phosphorylation of MYL9 protein] which results in decreased secretion of REN protein; [CACNA1D protein results in increased uptake of Calcium] which results in increased phosphorylation of MYL9 protein; [Escin affects the susceptibility to Calcium] which results in increased phosphorylation of MYL9 protein; Glycodeoxycholic Acid inhibits the reaction [[Escin affects the susceptibility to Calcium] which results in increased phosphorylation of MYL9 protein]; Y 27632 inhibits the reaction [[Escin affects the susceptibility to Calcium] which results in increased phosphorylation of MYL9 protein]
Calcium affects the phosphorylation of MYL9 protein
Calcium deficiency results in decreased phosphorylation of MYL9 protein
CTD PMID:7503253 PMID:9618396 PMID:17272349 PMID:29660437 NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333
JBrowse link
G Mylk myosin light chain kinase increases activity
multiple interactions
ISO
EXP
Calcium deficiency results in increased activity of MYLK protein; Calcium results in increased activity of MYLK protein
[[Calcium results in increased activity of MYLK protein] which results in increased phosphorylation of MYL9 protein] which results in decreased secretion of REN protein
ML 7 inhibits the reaction [Calcium deficiency results in increased activity of MYLK protein]
CTD PMID:9618396 PMID:10640419 PMID:11054866 NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
JBrowse link
G Myo1b myosin Ib increases activity EXP Calcium deficiency results in increased activity of MYO1B protein CTD PMID:10419463 NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798
JBrowse link
G Myo5a myosin VA affects activity ISO Calcium affects the activity of MYO5A protein CTD PMID:10660602 NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918
JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 decreases response to substance ISO NAIP protein results in decreased susceptibility to Calcium CTD PMID:12445469 NCBI chr 2:31,507,423...31,559,098
Ensembl chr 2:31,507,424...31,570,542
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 affects abundance ISO NCF1 protein affects the abundance of Calcium CTD PMID:16280459 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of NDUFS1 mRNA CTD PMID:15913539 NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase affects expression EXP Calcium affects the expression of NEDD4 mRNA CTD PMID:15913539 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase multiple interactions ISO [NEDD4L gene mutant form results in increased susceptibility to Sodium, Dietary] which results in increased abundance of Calcium; Thiazides inhibits the reaction [[NEDD4L gene mutant form results in increased susceptibility to Sodium, Dietary] which results in increased abundance of Calcium] CTD PMID:23348737 NCBI chr18:58,393,759...58,726,709
Ensembl chr18:58,393,509...58,723,137
JBrowse link
G Nefl neurofilament light chain multiple interactions EXP Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of NEFL protein]; calpeptin inhibits the reaction [Calcium results in increased degradation of NEFL protein]; Indomethacin inhibits the reaction [Calcium results in increased degradation of NEFL protein] CTD PMID:11071371 PMID:21879721 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
JBrowse link
G Nefm neurofilament medium chain multiple interactions EXP Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of NEFM protein] CTD PMID:21879721 NCBI chr15:42,360,449...42,365,753
Ensembl chr15:42,360,454...42,365,755
JBrowse link
G Nek9 NIMA-related kinase 9 affects expression EXP Calcium affects the expression of NEK9 mRNA CTD PMID:15913539 NCBI chr 6:104,944,056...104,984,538
Ensembl chr 6:104,944,056...104,984,538
JBrowse link
G Nf1 neurofibromin 1 decreases transport ISO NF1 protein results in decreased transport of Calcium CTD PMID:21949590 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658
JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 multiple interactions ISO 4-methyl-4'-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)-1,2,3-thiadiazole-5-carboxanilide inhibits the reaction [[Muscarine co-treated with Calcium] affects the localization of NFATC2 protein]; 4-methyl-4'-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)-1,2,3-thiadiazole-5-carboxanilide inhibits the reaction [[Thapsigargin co-treated with Calcium] affects the localization of NFATC2 protein]; [Muscarine co-treated with Calcium] affects the localization of NFATC2 protein; [Thapsigargin co-treated with Calcium] affects the localization of NFATC2 protein CTD PMID:24990931 NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases abundance ISO NFE2L2 gene mutant form results in increased abundance of Calcium CTD PMID:29618784 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha affects expression
multiple interactions
EXP
ISO
Calcium affects the expression of NFKBIA mRNA
Calcium affects the reaction [Morphine inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]
CTD PMID:15913539 PMID:24068670 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ngb neuroglobin affects transport ISO NGB protein affects the transport of Calcium CTD PMID:19154338 NCBI chr 6:106,744,378...106,749,830
Ensembl chr 6:106,744,378...106,749,830
JBrowse link
G Ngf nerve growth factor multiple interactions
increases uptake
EXP [NGF protein co-treated with 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester] results in increased uptake of Calcium; [NGF protein co-treated with Adenosine Triphosphate] results in increased uptake of Calcium; cadmium acetate inhibits the reaction [NGF protein results in increased uptake of Calcium]; Cadmium inhibits the reaction [NGF protein results in increased uptake of Calcium]; calmidazolium inhibits the reaction [NGF protein results in increased uptake of Calcium]; Fluphenazine inhibits the reaction [NGF protein results in increased uptake of Calcium]; Nifedipine inhibits the reaction [NGF protein results in increased uptake of Calcium]; Okadaic Acid promotes the reaction [NGF protein results in increased uptake of Calcium]; Staurosporine inhibits the reaction [NGF protein results in increased uptake of Calcium] CTD PMID:1374475 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Noa1 nitric oxide associated 1 multiple interactions EXP [Tamoxifen results in increased abundance of Calcium] which results in increased activity of NOA1 protein CTD PMID:17283165 NCBI chr14:30,835,012...30,851,296
Ensembl chr14:30,835,247...30,851,293
JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions EXP [Calcium binds to CALM1 protein] promotes the reaction [NOS1 protein results in increased chemical synthesis of Nitric Oxide]; [Calcium binds to CALM1 protein] which binds to and affects the folding of and results in increased activity of NOS1 protein CTD PMID:17098364 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos3 nitric oxide synthase 3 affects response to substance
increases activity
multiple interactions
ISO
EXP
NOS3 protein affects the susceptibility to Calcium
Calcium results in increased activity of NOS3 protein
Calcium affects the reaction [Polycyclic Aromatic Hydrocarbons results in increased expression of and results in increased activity of NOS3 protein]; Calcium deficiency inhibits the reaction [Digitoxin results in increased activity of NOS3 protein]; Calcium deficiency inhibits the reaction [ginsenoside Re results in increased phosphorylation of NOS3 protein]
CTD PMID:15183461 PMID:17403420 PMID:17490654 PMID:19380615 PMID:19446813 More... NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions ISO 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid inhibits the reaction [NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]]; NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]] CTD PMID:24912985 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236
JBrowse link
G Nppc natriuretic peptide C increases uptake
multiple interactions
EXP NPPC protein results in increased uptake of Calcium
Ammonia inhibits the reaction [NPPC protein results in increased uptake of Calcium]; Nimodipine inhibits the reaction [NPPC protein results in increased uptake of Calcium]
CTD PMID:18222015 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251
JBrowse link
G Npr1 natriuretic peptide receptor 1 affects expression EXP Calcium affects the expression of NPR1 mRNA CTD PMID:15913539 NCBI chr 2:175,934,181...175,950,118
Ensembl chr 2:175,934,181...175,949,505
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 affects expression EXP Calcium affects the expression of NR0B2 mRNA CTD PMID:15913539 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 affects expression EXP Calcium affects the expression of NR1D2 mRNA CTD PMID:15913539 NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553
JBrowse link
G Nrxn1 neurexin 1 multiple interactions ISO Calcium affects the reaction [alpha-latrotoxin binds to NRXN1 protein]; Calcium affects the reaction [black widow spider venom binds to NRXN1 protein] CTD PMID:9430716 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710
JBrowse link
G Nucb2 nucleobindin 2 multiple interactions EXP KT 5720 inhibits the reaction [NUCB2 protein results in increased import of Calcium] CTD PMID:17627999 NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353
JBrowse link
G Ocln occludin multiple interactions ISO Calcium deficiency inhibits the reaction [TJP1 protein binds to OCLN protein] CTD PMID:11054866 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Olr1519 olfactory receptor 1519 multiple interactions ISO [bourgeonal binds to and results in increased activity of OR1D2 protein] which results in increased abundance of Calcium CTD PMID:21454470 NCBI chr10:59,212,947...59,213,882
Ensembl chr10:59,207,257...59,214,085
JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Calcium] inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]] CTD PMID:18652891 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G Orai1 ORAI calcium release-activated calcium modulator 1 multiple interactions
increases uptake
EXP
ISO
[Calcium affects the activity of and affects the localization of STIM1 protein] which affects the activity of ORAI1 protein
ORAI1 protein results in increased uptake of Calcium
CTD PMID:23212906 PMID:24990931 NCBI chr12:33,533,151...33,548,361
Ensembl chr12:33,534,344...33,548,405
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide multiple interactions ISO
EXP
OXT protein promotes the reaction [TRPC3 protein results in increased transport of Calcium]
[Thapsigargin results in increased transport of Calcium] which results in increased secretion of OXT protein
CTD PMID:12700192 PMID:22028774 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
JBrowse link
G P2rx3 purinergic receptor P2X 3 multiple interactions ISO [alpha,beta-methyleneadenosine 5'-triphosphate binds to and results in increased activity of P2RX3 protein] which results in increased abundance of Calcium; Trichloroethylene inhibits the reaction [[alpha,beta-methyleneadenosine 5'-triphosphate binds to and results in increased activity of P2RX3 protein] which results in increased abundance of Calcium] CTD PMID:12694404 NCBI chr 3:70,080,850...70,124,664
Ensembl chr 3:70,080,851...70,125,178
JBrowse link
G P2rx7 purinergic receptor P2X 7 multiple interactions ISO [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium; KN 62 inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium]; protoberberine analog inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium] CTD PMID:21320518 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G P2ry1 purinergic receptor P2Y1 multiple interactions ISO
EXP
[Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein] which results in increased abundance of Calcium; Calcium affects the reaction [P2RY1 protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; Trichloroethylene inhibits the reaction [[Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein] which results in increased abundance of Calcium]
[N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate binds to and results in decreased activity of P2RY1 protein] inhibits the reaction [Adenosine Triphosphate results in increased uptake of Calcium]
CTD PMID:12694404 PMID:16236484 PMID:16973929 NCBI chr 2:145,241,975...145,248,186
Ensembl chr 2:145,241,849...145,248,457
JBrowse link
G P2ry2 purinergic receptor P2Y2 multiple interactions
affects response to substance
ISO
EXP
[Adenosine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Calcium
P2RY2 protein affects the susceptibility to Calcium
[Adenosine Triphosphate results in increased activity of P2RY2 protein] which results in increased uptake of Calcium; Go 6976 promotes the reaction [P2RY2 protein results in increased uptake of Calcium]; Tetradecanoylphorbol Acetate inhibits the reaction [P2RY2 protein results in increased uptake of Calcium]
CTD PMID:11527950 PMID:17003265 PMID:18343036 NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632
JBrowse link
G P2ry4 pyrimidinergic receptor P2Y4 multiple interactions ISO [Adenosine Triphosphate binds to and results in increased activity of P2RY4 protein] which results in increased abundance of Calcium; Trichloroethylene inhibits the reaction [[Adenosine Triphosphate binds to and results in increased activity of P2RY4 protein] which results in increased abundance of Calcium] CTD PMID:12694404 NCBI chr  X:65,681,680...65,717,404
Ensembl chr  X:65,683,232...65,721,748
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of P4HB mRNA CTD PMID:15913539 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 increases abundance
multiple interactions
ISO PAFAH1B1 protein results in increased abundance of Calcium
Calcium promotes the reaction [PAFAH1B1 protein binds to IQGAP1 protein binds to CDC42 protein]
PKD1 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium]; PKD2 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium]
CTD PMID:15001556 PMID:16369480 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808
JBrowse link
G Parg poly (ADP-ribose) glycohydrolase multiple interactions ISO PARG protein promotes the reaction [Hydrogen Peroxide results in increased uptake of Calcium] CTD PMID:20878536 NCBI chr16:7,436,429...7,544,276
Ensembl chr16:7,436,476...7,544,273
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO PARP1 protein promotes the reaction [Hydrogen Peroxide results in increased uptake of Calcium] CTD PMID:20878536 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pask PAS domain containing serine/threonine kinase multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of PASK mRNA CTD PMID:15913539 NCBI chr 9:93,844,275...93,886,036
Ensembl chr 9:93,844,278...93,885,111
JBrowse link
G Pax6 paired box 6 affects expression EXP Calcium affects the expression of PAX6 mRNA CTD PMID:15913539 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014
JBrowse link
G Pax8 paired box 8 affects expression EXP Calcium affects the expression of PAX8 mRNA CTD PMID:15913539 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
JBrowse link
G Pcdh19 protocadherin 19 affects binding ISO Calcium binds to PCDH19 protein CTD PMID:18469813 NCBI chr  X:96,767,686...96,873,477
Ensembl chr  X:96,771,947...96,873,524
JBrowse link
G Pdgfb platelet derived growth factor subunit B increases import ISO PDGFB protein results in increased import of Calcium CTD PMID:19576918 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 multiple interactions
affects abundance
ISO PDK1 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]
PDK1 protein affects the abundance of Calcium
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester affects the reaction [PDK1 protein affects the abundance of Calcium]; [PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium; Adenosine Triphosphate promotes the reaction [PDK1 protein affects the abundance of Calcium]; PDK1 protein affects the reaction [Thapsigargin affects the abundance of Calcium]; tubacin affects the reaction [[PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium]; tubacin affects the reaction [PDK1 protein affects the abundance of Calcium]; tubacin inhibits the reaction [PDK1 protein affects the reaction [Thapsigargin affects the abundance of Calcium]]
CTD PMID:28634229 PMID:28887310 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
JBrowse link
G Pdzd3 PDZ domain containing 3 multiple interactions ISO [[USP2 gene mutant form results in increased expression of PDZD3 protein] which results in increased activity of TRPV6 protein] which results in increased uptake of Calcium CTD PMID:26756164 NCBI chr 8:44,584,390...44,588,838
Ensembl chr 8:44,584,390...44,588,860
JBrowse link
G Pgp phosphoglycolate phosphatase decreases activity ISO Calcium results in decreased activity of PGP protein CTD PMID:24338473 NCBI chr10:13,495,232...13,497,858
Ensembl chr10:13,494,291...13,497,858
JBrowse link
G Pick1 protein interacting with PRKCA 1 multiple interactions EXP Calcium affects the reaction [PICK1 protein binds to AGO2 protein]; Calcium deficiency inhibits the reaction [Excitatory Amino Acid Agonists inhibits the reaction [PICK1 protein binds to AGO2 protein]]; Calcium promotes the reaction [PICK1 protein binds to GRIA2 protein] CTD PMID:28404816 NCBI chr 7:110,796,623...110,816,850
Ensembl chr 7:110,797,117...110,816,848
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta affects transport EXP PIK3CB protein affects the transport of Calcium CTD PMID:11597992 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta affects transport ISO PIK3CD protein affects the transport of Calcium CTD PMID:16179367 NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930
JBrowse link
G Pip5k1b phosphatidylinositol-4-phosphate 5-kinase type 1 beta affects expression EXP Calcium affects the expression of PIP5K1B mRNA CTD PMID:15913539 NCBI chr 1:221,907,220...222,183,672
Ensembl chr 1:221,914,159...222,183,672
JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting multiple interactions ISO PKD1 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium]
PKD1 protein affects the reaction [Caffeine affects the abundance of Calcium]; PKD1 protein affects the reaction [Thapsigargin affects the abundance of Calcium]
CTD PMID:15001556 PMID:18679710 NCBI chr10:13,573,779...13,621,138
Ensembl chr10:13,573,021...13,621,128
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel multiple interactions
increases transport
ISO PKD2 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium]
IFT88 protein affects the reaction [PKD2 protein results in increased uptake of Calcium]
PKD2 protein results in increased transport of Calcium
CTD PMID:15001556 PMID:15100357 PMID:16396941 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825
JBrowse link
G Pklr pyruvate kinase L/R multiple interactions EXP Calcium inhibits the reaction [Phenylephrine results in decreased activity of PKLR protein] CTD PMID:747652 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
JBrowse link
G Pla2g1b phospholipase A2 group IB multiple interactions
increases abundance
ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[PLA2G1B protein results in increased abundance of Calcium] which results in increased expression of CXCL8 protein]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [PLA2G1B protein results in increased abundance of Calcium]; [PLA2G1B protein results in increased abundance of Calcium] which results in increased expression of CXCL8 protein CTD PMID:15528384 NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226
JBrowse link
G Pla2g2a phospholipase A2 group IIA increases uptake
multiple interactions
EXP PLA2G2A protein results in increased uptake of Calcium
BQ 788 inhibits the reaction [EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium]]; EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium]
CTD PMID:15695168 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
JBrowse link
G Pla2g6 phospholipase A2 group VI increases activity
multiple interactions
EXP Calcium deficiency results in increased activity of PLA2G6 protein
6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2H-pyran-2-one inhibits the reaction [[Lipopolysaccharides results in increased expression of and results in increased activity of PLA2G6 protein] which results in increased susceptibility to Calcium]; [Lipopolysaccharides results in increased expression of and results in increased activity of PLA2G6 protein] which results in increased susceptibility to Calcium
CTD PMID:17885217 PMID:21178110 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114
JBrowse link
G Plcg2 phospholipase C, gamma 2 multiple interactions ISO Calcium promotes the reaction [PLCG2 protein mutant form results in increased chemical synthesis of Inositol Phosphates]; Calcium promotes the reaction [PLCG2 protein results in increased chemical synthesis of Inositol Phosphates] CTD PMID:27542411 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930
JBrowse link
G Pnoc prepronociceptin decreases abundance EXP PNOC protein results in decreased abundance of Calcium CTD PMID:21039959 NCBI chr15:39,624,635...39,652,463
Ensembl chr15:39,624,641...39,651,867
JBrowse link
G Pon1 paraoxonase 1 increases activity
multiple interactions
ISO
EXP
Calcium results in increased activity of PON1 protein
[Calcium results in increased activity of PON1 protein] which affects the susceptibility to O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate; [Calcium results in increased activity of PON1 protein] which affects the susceptibility to oxamyl; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Aldicarb; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to methylparaoxon; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Paraoxon
[Calcium co-treated with 1,2-dioleoyl-sn-glycero-3-phosphoglycerol] results in increased stability of PON1 protein; [Calcium co-treated with Oleic Acid] results in increased stability of PON1 protein; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Aldicarb; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to methylparaoxon; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to oxamyl; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Paraoxon; Calcium promotes the reaction [Oleic Acid inhibits the reaction [4-hydroxymercuribenzoate results in decreased activity of PON1 protein]]
CTD PMID:12871208 PMID:27132127 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Pon2 paraoxonase 2 affects abundance
multiple interactions
ISO PON2 gene polymorphism affects the abundance of Calcium
Calcium inhibits the reaction [lead acetate results in decreased activity of PON2 protein]
CTD PMID:16141008 PMID:22271317 NCBI chr 4:33,389,702...33,425,186
Ensembl chr 4:33,389,714...33,425,248
JBrowse link
G Pou6f1 POU class 6 homeobox 1 affects expression EXP Calcium affects the expression of POU6F1 mRNA CTD PMID:15913539 NCBI chr 7:131,677,719...131,700,869
Ensembl chr 7:131,680,141...131,686,843
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [GW 7647 binds to and results in increased activity of PPARA protein] affects the reaction [Glucose affects the abundance of Calcium]; [Oleylethanolamide binds to and results in increased activity of PPARA protein] affects the reaction [Glucose affects the abundance of Calcium]; [pirinixic acid binds to and results in increased activity of PPARA protein] affects the reaction [Glucose affects the abundance of Calcium] CTD PMID:19017711 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha affects expression EXP Calcium affects the expression of PPP1CA mRNA CTD PMID:15913539 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327
JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta affects expression EXP Calcium affects the expression of PPP1CB mRNA CTD PMID:15913539 NCBI chr 6:23,958,813...23,992,841
Ensembl chr 6:23,960,998...23,992,824
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A multiple interactions EXP [Egtazic Acid co-treated with Calcium deficiency] results in increased expression of PPP1R15A mRNA CTD PMID:9878749 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha affects abundance
affects transport
ISO PPP2CA protein affects the abundance of Calcium
PPP2CA protein affects the transport of Calcium
CTD PMID:15247211 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha multiple interactions
affects response to substance
ISO PPP3R1 gene mutant form inhibits the reaction [ATP2A2 protein affects the transport of Calcium]; PPP3R1 gene mutant form inhibits the reaction [SLC8A1 protein affects the transport of Calcium]
PPP3R1 gene mutant form affects the susceptibility to Calcium
CTD PMID:19700627 NCBI chr14:91,556,743...91,606,230
Ensembl chr14:91,604,121...91,606,907
JBrowse link
G Prdx6 peroxiredoxin 6 multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of PRDX6 mRNA CTD PMID:15913539 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
JBrowse link
G Prkca protein kinase C, alpha multiple interactions
increases response to substance
EXP [Tretinoin co-treated with Calcium] results in increased activity of PRKCA protein
PRKCA protein results in increased susceptibility to Calcium
CTD PMID:12388232 PMID:16114872 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkcb protein kinase C, beta multiple interactions ISO Calcium inhibits the reaction [Chlordecone results in increased activity of PRKCB protein]; Calcium inhibits the reaction [Dicofol results in increased activity of PRKCB protein] CTD PMID:1724372 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Prkcd protein kinase C, delta affects expression EXP Calcium affects the expression of PRKCD mRNA CTD PMID:15913539 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Prkce protein kinase C, epsilon multiple interactions
increases phosphorylation
affects response to substance
ISO PRKCE protein affects the reaction [Oxygen deficiency results in increased abundance of Calcium]
Calcium results in increased phosphorylation of PRKCE protein
chelerythrine inhibits the reaction [Calcium results in increased phosphorylation of PRKCE protein]; PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]]
PRKCE protein affects the susceptibility to Calcium
CTD PMID:15242976 PMID:16793902 PMID:17087917 PMID:21562303 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Prkcg protein kinase C, gamma multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Calcium] inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]] CTD PMID:18652891 NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384
JBrowse link
G Prkd1 protein kinase D1 multiple interactions ISO
EXP
PRKD1 promotes the reaction [Capsaicin results in increased uptake of Calcium]
PRKD1 mutant form inhibits the reaction [Capsaicin results in increased uptake of Calcium]
CTD PMID:15471852 NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 increases response to substance ISO PRKG1 protein results in increased susceptibility to Calcium CTD PMID:16533816 NCBI chr 1:228,409,883...229,638,794
Ensembl chr 1:228,408,947...229,639,080
JBrowse link
G Prl prolactin multiple interactions ISO Calcium inhibits the reaction [PRL protein binds to PRLR protein] CTD PMID:6197504 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Prlr prolactin receptor affects expression
multiple interactions
EXP
ISO
Calcium affects the expression of PRLR mRNA
Calcium inhibits the reaction [PRL protein binds to PRLR protein]
CTD PMID:6197504 PMID:15913539 NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718
JBrowse link
G Prok2 prokineticin 2 multiple interactions
increases abundance
ISO PROKR1 protein affects the reaction [PROK2 protein results in increased abundance of Calcium] CTD PMID:16793879 PMID:17107623 NCBI chr 4:132,346,681...132,361,754
Ensembl chr 4:132,347,103...132,361,385
JBrowse link
G Prokr1 prokineticin receptor 1 multiple interactions ISO PROKR1 protein affects the reaction [Capsaicin results in increased abundance of Calcium]; PROKR1 protein affects the reaction [PROK2 protein results in increased abundance of Calcium] CTD PMID:16793879 NCBI chr 4:120,022,301...120,033,379
Ensembl chr 4:120,021,747...120,033,379
JBrowse link
G Ptafr platelet-activating factor receptor multiple interactions EXP RGS4 protein inhibits the reaction [PTAFR protein affects the localization of and affects the abundance of Calcium] CTD PMID:11297424 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251
JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 multiple interactions ISO PTGDR2 protein affects the abundance of and affects the localization of Calcium CTD PMID:16256979 NCBI chr 1:207,585,088...207,590,275
Ensembl chr 1:207,587,917...207,589,213
JBrowse link
G Ptger1 prostaglandin E receptor 1 multiple interactions
increases abundance
ISO 17-phenyltrinorprostaglandin E2 inhibits the reaction [PTGER1 protein results in increased abundance of Calcium] CTD PMID:11809688 NCBI chr19:24,470,258...24,473,687
Ensembl chr19:24,467,532...24,473,559
JBrowse link
G Ptger3 prostaglandin E receptor 3 multiple interactions EXP PTGER3 protein affects the reaction [Dinoprostone results in decreased transport of Calcium]; PTGER3 protein affects the reaction [ONO AE 248 results in decreased transport of Calcium] CTD PMID:12535167 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
JBrowse link
G Ptgir prostaglandin I2 receptor multiple interactions ISO [cicaprost results in increased activity of PTGIR protein] which results in increased abundance of Calcium CTD PMID:11895442 NCBI chr 1:77,579,596...77,581,979
Ensembl chr 1:77,579,596...77,581,979
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 affects expression EXP Calcium affects the expression of PTGS1 mRNA CTD PMID:15913539 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO
EXP
Calcium affects the reaction [bisperoxovanadium results in increased expression of PTGS2 mRNA]
Calcium deficiency inhibits the reaction [Serotonin results in increased expression of PTGS2 mRNA]
Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]
CTD PMID:12493747 PMID:19782052 PMID:21262218 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Pth parathyroid hormone multiple interactions
increases stability
increases abundance
decreases abundance
affects metabolic processing
decreases expression
ISO
EXP
[Calcitriol co-treated with Calcium] results in decreased expression of PTH protein; [Cholecalciferol co-treated with Calcium] results in decreased expression of PTH protein
Calcium deficiency results in increased stability of PTH mRNA
Calcium affects the reaction [Aluminum Compounds results in decreased expression of PTH mRNA]; Calcium affects the reaction [Aluminum Compounds results in decreased secretion of PTH protein]; Calcium affects the reaction [Calcitriol results in decreased expression of PTH mRNA]; Calcium affects the reaction [Calcitriol results in decreased secretion of PTH protein]; Calcium deficiency inhibits the reaction [KHSRP protein binds to PTH 3' UTR]; Calcium deficiency promotes the reaction [HNRNPD protein binds to PTH 3' UTR]
PTH protein modified form results in increased abundance of Calcium
PTH protein results in decreased abundance of Calcium
PTH protein affects the metabolism of Calcium
Calcium results in decreased expression of PTH protein
CTD PMID:80633 PMID:6330156 PMID:15891005 PMID:16094769 PMID:16316325 More... NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530
JBrowse link
G Pth1r parathyroid hormone 1 receptor affects expression EXP Calcium affects the expression of PTH1R mRNA CTD PMID:15913539 NCBI chr 8:110,693,910...110,725,458
Ensembl chr 8:110,697,485...110,719,729
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta multiple interactions ISO
EXP
Calcium affects the reaction [(N)-methanocarba-2MeSADP results in increased phosphorylation of PTK2B protein]
Calcium affects the phosphorylation of and affects the activity of PTK2B protein
CTD PMID:16236484 PMID:16877402 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link
G Ptpn12 protein tyrosine phosphatase, non-receptor type 12 affects expression EXP Calcium affects the expression of PTPN12 mRNA CTD PMID:15913539 NCBI chr 4:14,020,997...14,092,931
Ensembl chr 4:14,021,052...14,092,927
JBrowse link
G Pygl glycogen phosphorylase L multiple interactions EXP [Phenylephrine co-treated with Calcium] results in increased activity of PYGL protein; Calcium deficiency inhibits the reaction [Calcimycin results in increased activity of PYGL protein]; Glucose inhibits the reaction [[Phenylephrine co-treated with Calcium] results in increased activity of PYGL protein] CTD PMID:747652 PMID:6430282 NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310
JBrowse link
G Rab7a RAB7A, member RAS oncogene family affects expression EXP Calcium affects the expression of RAB7 mRNA CTD PMID:15913539 NCBI chr 4:120,461,966...120,510,756
Ensembl chr 4:120,461,963...120,506,889
JBrowse link
G Ralgds ral guanine nucleotide dissociation stimulator affects expression EXP Calcium affects the expression of RALGDS mRNA CTD PMID:15913539 NCBI chr 3:11,839,686...11,880,059
Ensembl chr 3:11,839,416...11,880,059
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions ISO Calcium promotes the reaction [ibandronic acid results in decreased prenylation of RAP1A protein] CTD PMID:18190680 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 multiple interactions ISO RAPGEF3 protein promotes the reaction [Benzo(a)pyrene results in increased transport of Calcium] CTD PMID:22167199 NCBI chr 7:128,875,772...128,898,203
Ensembl chr 7:128,875,773...128,898,521
JBrowse link
G Rbp1 retinol binding protein 1 affects expression EXP Calcium affects the expression of RBP1 mRNA CTD PMID:15913539 NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743
JBrowse link
G Ren renin decreases secretion
multiple interactions
EXP Calcium results in decreased secretion of REN protein
[[Calcium results in increased activity of MYLK protein] which results in increased phosphorylation of MYL9 protein] which results in decreased secretion of REN protein; ML 7 inhibits the reaction [Calcium results in decreased secretion of REN protein]
CTD PMID:9618396 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Rgs4 regulator of G-protein signaling 4 multiple interactions EXP RGS4 protein inhibits the reaction [PTAFR protein affects the localization of and affects the abundance of Calcium] CTD PMID:11297424 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
JBrowse link
G Rps3a ribosomal protein S3a affects expression EXP Calcium affects the expression of RPS3A mRNA CTD PMID:15913539 NCBI chr 2:171,524,685...171,529,054
Ensembl chr 2:171,524,500...171,529,055
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions EXP
ISO
Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of RPS6KB1 protein]
[Resveratrol results in increased abundance of Calcium] which results in decreased expression of RPS6KB1 protein modified form; dorsomorphin inhibits the reaction [[Resveratrol results in increased abundance of Calcium] which results in decreased expression of RPS6KB1 protein modified form]
CTD PMID:12935885 PMID:23680031 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 multiple interactions ISO [Resveratrol results in increased abundance of Calcium] which results in increased activity of RPTOR protein modified form; dorsomorphin inhibits the reaction [[Resveratrol results in increased abundance of Calcium] which results in increased activity of RPTOR protein modified form] CTD PMID:23680031 NCBI chr10:104,878,487...105,176,986
Ensembl chr10:104,878,487...105,176,983
JBrowse link
G Rraga Ras-related GTP binding A affects expression EXP Calcium affects the expression of RRAGA mRNA CTD PMID:15913539 NCBI chr 5:101,113,341...101,114,936
Ensembl chr 5:101,112,859...101,114,510
JBrowse link
G Ryr1 ryanodine receptor 1 multiple interactions
affects abundance
increases secretion
increases abundance
ISO
EXP
[Caffeine results in increased activity of RYR1 protein] which affects the localization of Calcium; [chlorocresol results in increased activity of RYR1 protein] which affects the localization of Calcium; [chlorocresol results in increased activity of RYR1 protein] which results in increased transport of Calcium; [Halothane results in increased activity of RYR1 protein] which affects the localization of Calcium; [RYR1 protein co-treated with 2,3,6,2',3',6'-hexachlorobiphenyl] affects the susceptibility to Calcium; Calcium affects the folding of [CALM1 protein binds to RYR1 protein modified form]; Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]; Dantrolene inhibits the reaction [[chlorocresol results in increased activity of RYR1 protein] which results in increased transport of Calcium]; RYR1 protein polymorphism affects the reaction [Caffeine results in increased secretion of Calcium]; RYR1 protein polymorphism affects the reaction [chlorocresol results in increased secretion of Calcium]
RYR1 protein polymorphism affects the abundance of Calcium
RYR1 protein mutant form results in increased secretion of Calcium
RYR1 gene mutant form results in increased abundance of Calcium
Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]; Calcium affects the reaction [CALM1 protein modified form binds to and affects the activity of RYR1 protein]
CTD PMID:15381065 PMID:15628869 PMID:16372898 PMID:17707769 PMID:18719443 More... NCBI chr 1:84,292,578...84,423,799
Ensembl chr 1:84,292,578...84,423,812
JBrowse link
G Ryr2 ryanodine receptor 2 multiple interactions ISO
EXP
FKBP1A protein inhibits the reaction [Calcium results in increased activity of RYR2 protein]
Dantrolene inhibits the reaction [Caffeine promotes the reaction [RYR2 protein results in increased secretion of Calcium]]; HOMER1 protein alternative form inhibits the reaction [Caffeine promotes the reaction [RYR2 protein results in increased secretion of Calcium]]; HOMER1 protein alternative form inhibits the reaction [Cyclic ADP-Ribose promotes the reaction [RYR2 protein results in increased secretion of Calcium]]
CTD PMID:12887973 PMID:17872463 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142
JBrowse link
G S100a13 S100 calcium binding protein A13 multiple interactions ISO [Calcium co-treated with Copper] binds to and affects the folding of S100A13 protein; Calcium binds to and affects the folding of S100A13 protein CTD PMID:16766622 NCBI chr 2:175,999,439...176,005,933 JBrowse link
G S100a2 S100 calcium binding protein A2 multiple interactions
affects binding
ISO [Zinc binds to S100A2 protein] inhibits the reaction [Calcium binds to S100A2 protein] CTD PMID:17239974 NCBI chr 2:176,075,060...176,078,782 JBrowse link
G S100a6 S100 calcium binding protein A6 affects response to substance ISO S100A6 protein affects the susceptibility to Calcium CTD PMID:15068510 NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180
JBrowse link
G S100a8 S100 calcium binding protein A8 multiple interactions
affects binding
ISO [Zinc co-treated with Calcium] binds to [S100A8 protein binds to S100A9 protein]
Calcium binds to [S100A8 protein binds to S100A9 protein]
CTD PMID:17050004 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
JBrowse link
G S100a9 S100 calcium binding protein A9 affects binding
multiple interactions
ISO Calcium binds to [S100A8 protein binds to S100A9 protein]
[Zinc co-treated with Calcium] binds to [S100A8 protein binds to S100A9 protein]
CTD PMID:17050004 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
JBrowse link
G S100g S100 calcium binding protein G affects expression EXP Calcium affects the expression of S100G mRNA CTD PMID:15913539 NCBI chr  X:31,705,853...31,708,422
Ensembl chr  X:31,705,866...31,708,433
JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 increases expression ISO Calcium results in increased expression of SCGB1A1 mRNA; Calcium results in increased expression of SCGB1A1 protein CTD PMID:16237193 NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610
JBrowse link
G Sct secretin increases abundance ISO SCT protein results in increased abundance of Calcium CTD PMID:1220513 NCBI chr 1:196,382,941...196,383,635
Ensembl chr 1:196,382,856...196,383,658
JBrowse link
G Sec61a1 SEC61 translocon subunit alpha 1 multiple interactions
increases transport
ISO [HSPA5 protein binds to SEC61A1 protein] which results in decreased transport of Calcium; [SEC61A1 protein results in increased transport of Calcium] which results in increased susceptibility to Thapsigargin; DNAJB11 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium]; DNAJC3 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium] CTD PMID:26085089 NCBI chr 4:120,973,519...120,987,871
Ensembl chr 4:120,960,626...120,987,925
JBrowse link
G Selenot selenoprotein T multiple interactions
affects abundance
EXP Calcium affects the reaction [ADCYAP1 protein results in increased expression of SELENOT mRNA]; SELENOT protein affects the reaction [ADCYAP1 protein results in increased abundance of Calcium]; Thapsigargin promotes the reaction [SELENOT protein affects the abundance of Calcium] CTD PMID:18198219 NCBI chr 2:142,804,387...142,821,438
Ensembl chr 2:142,804,405...142,821,427
JBrowse link
G Serpine1 serpin family E member 1 increases stability ISO Calcium results in increased stability of SERPINE1 protein CTD PMID:21280127 PMID:21280128 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Slc12a5 solute carrier family 12 member 5 multiple interactions EXP Calcium affects the reaction [Zinc results in increased activity of SLC12A5 protein] CTD PMID:22441041 NCBI chr 3:153,696,522...153,735,801
Ensembl chr 3:153,696,517...153,735,765
JBrowse link
G Slc23a2 solute carrier family 23 member 2 decreases expression
multiple interactions
increases expression
ISO Calcium deficiency results in decreased expression of SLC23A2 mRNA
Foscarnet inhibits the reaction [Calcium results in increased expression of SLC23A2 mRNA]; Nifedipine inhibits the reaction [Calcium results in increased expression of SLC23A2 mRNA]
Calcium results in increased expression of SLC23A2 mRNA; Calcium results in increased expression of SLC23A2 protein
CTD PMID:12788230 NCBI chr 3:119,302,651...119,395,289
Ensembl chr 3:119,302,666...119,460,343
JBrowse link
G Slc24a2 solute carrier family 24 member 2 increases uptake EXP SLC24A2 protein results in increased uptake of Calcium CTD PMID:14660663 NCBI chr 5:101,499,536...101,739,337
Ensembl chr 5:101,502,278...101,739,337
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions EXP Calcium deficiency inhibits the reaction [2,3-dinitrophenol results in increased activity of SLC2A1 protein]; Calcium deficiency inhibits the reaction [Arsenates results in increased activity of SLC2A1 protein]; Calcium deficiency inhibits the reaction [Azides results in increased activity of SLC2A1 protein]; Calcium deficiency inhibits the reaction [INS1 protein results in increased activity of SLC2A1 protein] CTD PMID:10970766 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Slc2a2 solute carrier family 2 member 2 multiple interactions EXP [CACNA1D protein results in increased uptake of Calcium] which affects the localization of SLC2A2 protein CTD PMID:17272349 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions EXP [[Chloroquine results in increased abundance of Calcium] which affects the localization of SLC2A4 protein] which results in increased uptake of Glucose; [Chloroquine results in increased abundance of Calcium] which affects the localization of SLC2A4 protein CTD PMID:27160165 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc30a1 solute carrier family 30 member 1 multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of SLC30A1 mRNA CTD PMID:15913539 NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
JBrowse link
G Slc5a1 solute carrier family 5 member 1 multiple interactions EXP SLC5A1 protein affects the reaction [CACNA1D protein results in increased uptake of Calcium] CTD PMID:17272349 NCBI chr14:77,553,990...77,618,589
Ensembl chr14:77,553,843...77,618,547
JBrowse link
G Slc8a1 solute carrier family 8 member A1 multiple interactions
increases transport
ISO
EXP
Calcium inhibits the reaction [SLC8A1 protein results in increased uptake of Nickel]
PPP3R1 gene mutant form inhibits the reaction [SLC8A1 protein affects the transport of Calcium]
SLC8A1 protein results in increased transport of Calcium
2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [SLC8A1 protein results in increased transport of Calcium]
CTD PMID:10329968 PMID:18822394 PMID:19700627 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628
JBrowse link
G Slc8a2 solute carrier family 8 member A2 increases uptake EXP SLC8A2 protein results in increased uptake of Calcium CTD PMID:14660663 NCBI chr 1:76,816,583...76,852,928
Ensembl chr 1:76,808,725...76,847,072
JBrowse link
G Slc8a3 solute carrier family 8 member A3 increases transport
increases uptake
EXP
ISO
SLC8A3 protein results in increased transport of Calcium
SLC8A3 protein results in increased uptake of Calcium
CTD PMID:14660663 PMID:17585341 PMID:29434186 NCBI chr 6:100,874,359...101,007,989
Ensembl chr 6:100,874,369...101,007,508
JBrowse link
G Slc9a1 solute carrier family 9 member A1 multiple interactions EXP 3-methylsulfonyl-4-piperidinobenzoyl guanidine inhibits the reaction [[Phenylephrine results in increased activity of SLC9A1 protein] which results in increased transport of Calcium]; [[Phenylephrine results in increased activity of SLC9A1 protein] which results in increased transport of Calcium] which results in increased expression of ATP2A2 protein; [Phenylephrine results in increased activity of SLC9A1 protein] which results in increased transport of Calcium CTD PMID:16236312 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624
JBrowse link
G Snca synuclein alpha multiple interactions
increases uptake
EXP omega-Conotoxin GVIA inhibits the reaction [SNCA protein results in increased uptake of Calcium] CTD PMID:17179863 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
increases transport
ISO
EXP
SOD1 protein mutant form promotes the reaction [SOD1 protein binds to Calcium]
SOD1 protein modified form results in increased transport of Calcium; SOD1 protein results in increased transport of Calcium
[Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in decreased activity of SOD1 protein]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in decreased activity of SOD1 protein]; [Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of SOD1 protein]; Calcium affects the reaction [sodium arsenite results in decreased activity of SOD1 protein]
CTD PMID:19227972 PMID:22534743 PMID:24184500 PMID:28085149 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP [Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in decreased activity of SOD2 protein]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in decreased activity of SOD2 protein]; [Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of SOD2 protein]; Calcium affects the reaction [sodium arsenite results in decreased activity of SOD2 protein] CTD PMID:22534743 PMID:24184500 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sphk1 sphingosine kinase 1 multiple interactions ISO [C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium; resveratrol inhibits the reaction [[C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium] CTD PMID:19284563 PMID:19346296 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression
affects expression
multiple interactions
ISO
EXP
Calcium results in increased expression of SPP1 mRNA
Calcium affects the expression of SPP1 mRNA
Foscarnet inhibits the reaction [Calcium results in increased expression of SPP1 mRNA]; Nifedipine inhibits the reaction [Calcium results in increased expression of SPP1 mRNA]
CTD PMID:12788230 PMID:15913539 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Spp2 secreted phosphoprotein 2 affects expression EXP Calcium affects the expression of SPP2 mRNA CTD PMID:15913539 NCBI chr 9:89,006,858...89,026,676
Ensembl chr 9:89,007,175...89,026,688
JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 multiple interactions
increases cleavage
EXP ((1S)-1-((((1S)-1-benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester inhibits the reaction [Calcium results in increased cleavage of SPTAN1 protein]; Edetic Acid inhibits the reaction [Calcium results in increased cleavage of SPTAN1 protein]; N-(4-fluorophenylsulfonyl)-L-valyl-L-leucinal inhibits the reaction [Calcium results in increased cleavage of SPTAN1 protein] CTD PMID:17069801 NCBI chr 3:13,241,164...13,306,047
Ensembl chr 3:13,241,217...13,306,046
JBrowse link
G Sqstm1 sequestosome 1 affects expression EXP Calcium affects the expression of SQSTM1 mRNA CTD PMID:15913539 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase affects transport
multiple interactions
affects response to substance
ISO SRC protein affects the transport of Calcium
Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of SRC protein]
SRC protein affects the susceptibility to Calcium
CTD PMID:17551092 PMID:19782052 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO Calcium inhibits the reaction [Cyclic AMP results in increased expression of STAR protein] CTD PMID:19822634 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO Calcium promotes the reaction [[Diclofenac co-treated with IFNG protein] results in increased phosphorylation of STAT1 protein] CTD PMID:26609140 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Stim1 stromal interaction molecule 1 affects abundance
increases uptake
multiple interactions
ISO
EXP
STIM1 protein affects the abundance of Calcium
STIM1 protein results in increased uptake of Calcium
[Calcium affects the activity of and affects the localization of STIM1 protein] which affects the activity of ORAI1 protein; STIM1 protein promotes the reaction [Taurodeoxycholic Acid results in increased abundance of Calcium]
CTD PMID:18342630 PMID:18439569 PMID:23212906 PMID:24990931 NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363
JBrowse link
G Stmn1 stathmin 1 affects expression EXP Calcium affects the expression of STMN1 mRNA CTD PMID:15913539 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Sugt1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone multiple interactions ISO Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to SUGT1 protein]] CTD PMID:23184943 NCBI chr15:54,991,419...55,032,244
Ensembl chr15:54,990,672...55,069,150
JBrowse link
G Syn2 synapsin II multiple interactions
decreases abundance
ISO SYN2 mutant form inhibits the reaction [Adenosine Triphosphate results in increased abundance of Calcium]
SYN2 mutant form results in decreased abundance of Calcium
CTD PMID:18701217 NCBI chr 4:148,178,846...148,347,010
Ensembl chr 4:148,186,270...148,344,192
JBrowse link
G Syt1 synaptotagmin 1 affects binding EXP Calcium binds to SYT1 protein CTD PMID:16262243 NCBI chr 7:43,813,204...44,358,020
Ensembl chr 7:43,815,785...44,357,803
JBrowse link
G Tac1 tachykinin, precursor 1 increases transport ISO TAC1 protein modified form results in increased transport of Calcium CTD PMID:30116771 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Taok1 TAO kinase 1 affects expression EXP Calcium affects the expression of TAOK1 mRNA CTD PMID:15913539 NCBI chr10:62,373,076...62,465,295
Ensembl chr10:62,381,404...62,465,766
JBrowse link
G Tbxa2r thromboxane A2 receptor multiple interactions
increases transport
ISO rosiglitazone inhibits the reaction [TBXA2R protein results in increased transport of Calcium]; troglitazone inhibits the reaction [TBXA2R protein results in increased transport of Calcium] CTD PMID:16499875 NCBI chr 7:8,383,347...8,390,753
Ensembl chr 7:8,383,378...8,388,176
JBrowse link
G Tgfa transforming growth factor alpha increases abundance ISO TGFA protein results in increased abundance of Calcium CTD PMID:11527950 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases abundance
increases uptake
ISO
EXP
TGFB1 protein results in increased abundance of Calcium
TGFB1 protein results in increased uptake of Calcium
CTD PMID:15703175 PMID:17090780 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgm1 transglutaminase 1 increases expression
multiple interactions
ISO Calcium results in increased expression of TGM1 mRNA
NPS R-467 promotes the reaction [Calcium results in increased expression of TGM1 mRNA]
CTD PMID:10469331 NCBI chr15:29,191,039...29,206,000
Ensembl chr15:29,191,041...29,204,523
JBrowse link
G Timm17a translocase of inner mitochondrial membrane 17A affects expression EXP Calcium affects the expression of TIMM17A mRNA CTD PMID:15913539 NCBI chr13:46,731,117...46,742,604
Ensembl chr13:46,730,660...46,742,655
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions ISO Calcium deficiency inhibits the reaction [TJP1 protein binds to OCLN protein] CTD PMID:11054866 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]]
[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]; [TNF protein co-treated with IFNG protein] promotes the reaction [Diclofenac affects the abundance of Calcium]; Calcium affects the reaction [Morphine inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]
CTD PMID:23747339 PMID:24068670 PMID:26609140 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 multiple interactions ISO Calcium promotes the reaction [ITIH1 protein binds to TNFAIP6 protein]; Calcium promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B multiple interactions ISO TNFRSF11B protein inhibits the reaction [IL11 protein results in increased abundance of Calcium]; TNFRSF11B protein inhibits the reaction [TNFSF11 protein results in increased abundance of Calcium] CTD PMID:12110441 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions
increases abundance
ISO TNFRSF11B protein inhibits the reaction [TNFSF11 protein results in increased abundance of Calcium] CTD PMID:12110441 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Tnnc1 troponin C1, slow skeletal and cardiac type affects binding ISO TNNC1 protein binds to Calcium CTD PMID:18212018 NCBI chr16:6,400,801...6,405,419
Ensembl chr16:6,402,171...6,405,634
JBrowse link
G Tp53 tumor protein p53 decreases expression
affects localization
ISO Calcium results in decreased expression of TP53 protein
TP53 protein affects the localization of Calcium
CTD PMID:15059885 PMID:16043423 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp73 tumor protein p73 multiple interactions ISO [Calcium co-treated with CAPN1 protein] results in increased degradation of TP73 protein modified form CTD PMID:21516125 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 affects activity
multiple interactions
ISO
EXP
Calcium affects the activity of TRPA1 protein
[allicin binds to and results in increased activity of TRPA1 protein] which results in increased transport of Calcium; [allyl isothiocyanate binds to and results in increased activity of TRPA1 protein] which results in increased transport of Calcium; [cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester co-treated with TRPA1 protein] results in increased uptake of Calcium; Calcium affects the reaction [Capsaicin inhibits the reaction [TRPA1 protein affects the susceptibility to mustard oil]]; TRPA1 affects the reaction [AM 1241 results in increased abundance of Calcium]; TRPA1 promotes the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased abundance of Calcium]; TRPA1 promotes the reaction [mustard oil results in increased abundance of Calcium]
4-(4-chlorophenyl)-3-methylbut-3-en-2-oxime inhibits the reaction [[2-chloroethyl ethyl sulfide results in increased activity of TRPA1 protein] which results in increased uptake of Calcium]; 4-(4-chlorophenyl)-3-methylbut-3-en-2-oxime inhibits the reaction [[Mustard Gas results in increased activity of TRPA1 protein] which results in increased uptake of Calcium]; [2-chloroethyl ethyl sulfide results in increased activity of TRPA1 protein] which results in increased uptake of Calcium; [allyl isothiocyanate results in increased activity of TRPA1 protein] which results in increased uptake of Calcium; [cannabidivarin results in increased activity of TRPA1 protein] which results in increased uptake of Calcium; [Cannabinol results in increased activity of TRPA1 protein] which results in increased uptake of Calcium; [cinnamaldehyde results in increased activity of TRPA1 protein] which results in increased transport of Calcium; [cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester co-treated with TRPA1 protein] results in increased uptake of Calcium; [hydroquinone results in increased activity of TRPA1 protein] which results in increased import of Calcium; [Mustard Gas results in increased activity of TRPA1 protein] which results in increased uptake of Calcium; [Pyruvaldehyde results in increased activity of TRPA1 protein] which results in increased transport of Calcium; [Vehicle Emissions results in increased activity of TRPA1 protein] which results in increased import of Calcium; Acetylcysteine inhibits the reaction [[allyl isothiocyanate results in increased activity of TRPA1 protein] which results in increased uptake of Calcium]; Acetylcysteine inhibits the reaction [[Mustard Gas results in increased activity of TRPA1 protein] which results in increased uptake of Calcium]; Dithiothreitol inhibits the reaction [[hydroquinone results in increased activity of TRPA1 protein] which results in increased import of Calcium]; mustard oil promotes the reaction [[hydroquinone results in increased activity of TRPA1 protein] which results in increased import of Calcium]; TRPA1 mRNA affects the reaction [Acrolein results in increased uptake of Calcium]; TRPA1 mRNA affects the reaction [allyl isothiocyanate results in increased uptake of Calcium]; TRPA1 mRNA affects the reaction [cinnamaldehyde results in increased uptake of Calcium]
CTD PMID:15843607 PMID:17314320 PMID:17590514 PMID:18234885 PMID:19507004 More... NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570
JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 increases transport
increases import
multiple interactions
increases uptake
decreases transport
EXP
ISO
TRPC1 protein results in increased transport of Calcium
TRPC1 protein results in increased import of Calcium
LEP protein promotes the reaction [TRPC1 protein results in increased transport of Calcium]
TRPC1 protein results in increased uptake of Calcium
TRPC1 protein results in decreased transport of Calcium
CTD PMID:17174323 PMID:18822394 PMID:20107083 PMID:22157757 PMID:24953315 NCBI chr 8:96,263,322...96,314,197
Ensembl chr 8:96,263,329...96,314,276
JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 multiple interactions
increases transport
affects transport
affects secretion
ISO
EXP
1-oleoyl-2-acetylglycerol affects the reaction [TRPC3 protein affects the transport of Calcium]; 1-oleoyl-2-acetylglycerol promotes the reaction [TRPC3 protein results in increased transport of Calcium]; OXT protein promotes the reaction [TRPC3 protein results in increased transport of Calcium]; Thapsigargin promotes the reaction [TRPC3 protein results in increased transport of Calcium]
TRPC3 protein affects the secretion of Calcium
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [[Phenylephrine results in increased expression of TRPC3 protein] which results in increased transport of Calcium]; [Phenylephrine results in increased expression of TRPC3 protein] which results in increased transport of Calcium; TRPC3 protein promotes the reaction [1-oleoyl-2-acetoyl-sn-glycerol results in increased transport of Calcium]; TRPC3 protein promotes the reaction [Phenylephrine results in increased transport of Calcium]; TRPC3 protein promotes the reaction [Thapsigargin results in increased transport of Calcium]
CTD PMID:12700192 PMID:12736256 PMID:15672411 PMID:16484216 PMID:17351372 More... NCBI chr 2:119,481,313...119,619,333
Ensembl chr 2:119,481,400...119,558,855
JBrowse link
G Trpc4 transient receptor potential cation channel, subfamily C, member 4 multiple interactions
increases transport
ISO TRPC4 protein affects the reaction [Arachidonic Acid results in increased transport of Calcium]; TRPC4 protein affects the reaction [Carbachol results in increased transport of Calcium]
TRPC4 protein results in increased transport of Calcium
LEP protein promotes the reaction [TRPC4 protein results in increased transport of Calcium]
CTD PMID:11830588 PMID:20107083 NCBI chr 2:138,307,676...138,476,856
Ensembl chr 2:138,308,084...138,476,768
JBrowse link
G Trpc5 transient receptor potential cation channel, subfamily C, member 5 multiple interactions
increases transport
affects transport
ISO 1-oleoyl-2-acetylglycerol affects the reaction [TRPC5 protein affects the transport of Calcium]; 2-aminoethoxydiphenyl borate promotes the reaction [Resveratrol inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]]; Ascorbic Acid inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; Calcium promotes the reaction [Resveratrol inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]]; Carbachol promotes the reaction [TRPC5 protein results in increased transport of Calcium]; CAT protein inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; CAT protein inhibits the reaction [Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; Diethylstilbestrol inhibits the reaction [TRPC5 protein results in increased transport of Calcium]; Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]; Gallic Acid inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; Gallic Acid inhibits the reaction [Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]; Lysophosphatidylcholines promotes the reaction [TRPC5 protein results in increased transport of Calcium]; Resveratrol inhibits the reaction [Carbachol promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; Resveratrol inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; Resveratrol inhibits the reaction [Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; Resveratrol inhibits the reaction [Lysophosphatidylcholines promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; Resveratrol inhibits the reaction [TRPC5 protein results in increased transport of Calcium]; Resveratrol promotes the reaction [Ascorbic Acid inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]]
LEP protein promotes the reaction [TRPC5 protein results in increased transport of Calcium]
CTD PMID:17351372 PMID:20107083 PMID:21127073 NCBI chr  X:107,946,163...108,230,978
Ensembl chr  X:107,939,131...108,230,991
JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 affects transport
increases uptake
multiple interactions
increases transport
ISO
EXP
TRPC6 protein affects the transport of Calcium
TRPC6 protein results in increased uptake of Calcium
1,2-dioctanoylglycerol promotes the reaction [TRPC6 protein results in increased uptake of Calcium]; 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [1-oleoyl-2-acetoyl-sn-glycerol promotes the reaction [TRPC6 protein results in increased uptake of Calcium]]; 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [Acetylcholine promotes the reaction [TRPC6 protein results in increased uptake of Calcium]]; 1-oleoyl-2-acetoyl-sn-glycerol promotes the reaction [Acetylcholine promotes the reaction [TRPC6 protein results in increased uptake of Calcium]]; 1-oleoyl-2-acetoyl-sn-glycerol promotes the reaction [TRPC6 protein results in increased uptake of Calcium]; 2-aminoethyl diphenylborinate inhibits the reaction [Acetylcholine promotes the reaction [TRPC6 protein results in increased uptake of Calcium]]; 2-aminoethyl diphenylborinate inhibits the reaction [Thapsigargin promotes the reaction [TRPC6 protein results in increased uptake of Calcium]]; Acetylcholine promotes the reaction [TRPC6 protein results in increased uptake of Calcium]; Flufenamic Acid inhibits the reaction [1-oleoyl-2-acetoyl-sn-glycerol promotes the reaction [TRPC6 protein results in increased uptake of Calcium]]; Thapsigargin promotes the reaction [TRPC6 protein results in increased uptake of Calcium]; TRPC6 protein promotes the reaction [1-oleoyl-2-acetoyl-sn-glycerol results in increased transport of Calcium]; TRPC6 protein promotes the reaction [Phenylephrine results in increased transport of Calcium]
[Diglycerides results in increased activity of TRPC6 protein] which results in increased abundance of Calcium; [Flufenamic Acid results in increased activity of TRPC6 protein] which results in increased uptake of Calcium; CASR protein promotes the reaction [TRPC6 protein results in increased uptake of Calcium]; TRPC6 protein promotes the reaction [[VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium]; VEGFA protein promotes the reaction [[Diglycerides results in increased activity of TRPC6 protein] which results in increased abundance of Calcium]
TRPC6 protein results in increased transport of Calcium
CTD PMID:11179201 PMID:11535132 PMID:14551041 PMID:15672411 PMID:18209485 More... NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 increases transport
multiple interactions
ISO
EXP
TRPM2 protein results in increased transport of Calcium
TRPM2 protein promotes the reaction [Adenosine Diphosphate Ribose results in increased uptake of Calcium]; TRPM2 protein promotes the reaction [Hydrogen Peroxide results in increased uptake of Calcium]
[Clotrimazole results in decreased activity of TRPM2 protein] inhibits the reaction [Mustard Gas results in increased abundance of Calcium]; [Econazole results in decreased activity of TRPM2 protein] inhibits the reaction [Mustard Gas results in increased abundance of Calcium]; TRPM2 protein affects the reaction [Mustard Gas results in increased abundance of Calcium]
Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]; Calcium affects the reaction [Hydrogen Peroxide promotes the reaction [TRPM2 protein results in increased transport of Calcium]]; Clotrimazole inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]]; Flufenamic Acid inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]]; Hydrogen Peroxide promotes the reaction [TRPM2 protein results in increased transport of Calcium]
CTD PMID:12529379 PMID:20878536 PMID:21900507 PMID:22036725 NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 multiple interactions
increases activity
EXP
ISO
Calcium binds to and results in increased activity of TRPM4 protein
[Ionomycin co-treated with Calcium co-treated with CAMK2D protein] results in increased activity of TRPM4 protein
Calcium results in increased activity of TRPM4 protein
CTD PMID:16966582 PMID:17188667 PMID:33392831 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532
JBrowse link
G Trpm6 transient receptor potential cation channel, subfamily M, member 6 multiple interactions ISO Gadolinium inhibits the reaction [TRPM6 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Calcium]]; Lanthanum inhibits the reaction [TRPM6 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Calcium]]; TRPM6 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Calcium]; TRPM6 protein affects the reaction [1-stearoyl-2-arachidonoylglycerol results in increased transport of Calcium] CTD PMID:11988098 NCBI chr 1:216,136,407...216,320,523
Ensembl chr 1:216,170,038...216,320,520
JBrowse link
G Trpm7 transient receptor potential cation channel, subfamily M, member 7 increases abundance
decreases abundance
multiple interactions
ISO TRPM7 protein results in increased abundance of Calcium
TRPM7 gene mutant form results in decreased abundance of Calcium
Magnesium inhibits the reaction [TRPM7 protein results in increased abundance of Calcium]
CTD PMID:19515901 PMID:30770447 NCBI chr 3:114,046,258...114,134,799
Ensembl chr 3:114,046,258...114,135,190
JBrowse link
G Trpm8 transient receptor potential cation channel, subfamily M, member 8 affects transport
multiple interactions
increases transport
EXP
ISO
TRPM8 protein affects the transport of Calcium
[icilin binds to and results in increased activity of TRPM8 protein] which affects the abundance of Calcium; [Menthol binds to and results in increased activity of TRPM8 protein] which affects the abundance of Calcium
TRPM8 protein results in increased transport of Calcium
[icilin results in increased activity of TRPM8 protein] which results in increased transport of Calcium; [Menthol analog binds to and results in increased activity of TRPM8 protein] which results in increased transport of Calcium; [Menthol results in increased activity of TRPM8 protein] which results in increased transport of Calcium; Calcium deficiency inhibits the reaction [Praziquantel results in increased activity of TRPM8 protein]; icilin promotes the reaction [TRPM8 protein results in increased transport of Calcium]; Menthol promotes the reaction [TRPM8 protein results in increased transport of Calcium]
CTD PMID:16174775 PMID:17517434 PMID:18485891 PMID:18524940 PMID:19363131 More... NCBI chr 9:88,897,039...88,990,167
Ensembl chr 9:88,903,880...88,988,552
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 affects import
multiple interactions
increases import
ISO
EXP
TRPV1 protein affects the import of Calcium
3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [anandamide promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [arachidonyl dopamine promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [N-oleoyldopamine promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; [Capsaicin results in increased activity of TRPV1 protein] which results in increased transport of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin results in increased activity of TRPV1] which results in increased uptake of Calcium; [Formaldehyde results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium; Butyrates promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Calcium affects the reaction [Capsaicin inhibits the reaction [TRPV1 protein affects the susceptibility to Capsaicin]]; Calcium affects the reaction [mustard oil inhibits the reaction [TRPV1 protein affects the susceptibility to Capsaicin]]; capsazepine inhibits the reaction [[Formaldehyde results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]; capsazepine inhibits the reaction [[Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; HTR2A protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; HTR7 protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; Indomethacin inhibits the reaction [[Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; Lidocaine promotes the reaction [TRPV1 protein results in increased abundance of Calcium]; Masoprocol inhibits the reaction [[Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; Serotonin promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased transport of Calcium]
3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [anandamide promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [arachidonyl dopamine promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [N-oleoyldopamine promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [Protons promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; [arachidonyl dopamine results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [cannabichromene results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [Cannabidiol results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [cannabidiolic acid results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [cannabidivarin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [cannabigerol results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [cannabigerolic acid results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin binds to and results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [Capsaicin binds to TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased import of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin results in increased activity of TRPV1] which results in increased uptake of Calcium; [N-oleoyldopamine results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [nonivamide binds to and results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [resiniferatoxin binds to and results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [resiniferatoxin binds to TRPV1 protein] which results in increased uptake of Calcium; Cannabidiol inhibits the reaction [[Capsaicin binds to TRPV1 protein] which results in increased uptake of Calcium]; Cannabidiol inhibits the reaction [[resiniferatoxin binds to TRPV1 protein] which results in increased uptake of Calcium]; Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]; Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]; capsazepine inhibits the reaction [[Cannabidiol results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; capsazepine inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]]; capsazepine inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; capsazepine inhibits the reaction [Sodium affects the reaction [TRPV1 protein results in increased abundance of Calcium]]; Edetic Acid inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]; iodoresiniferatoxin inhibits the reaction [[N-oleoyldopamine results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; iodoresiniferatoxin inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]]; iodoresiniferatoxin inhibits the reaction [Sodium affects the reaction [TRPV1 protein results in increased abundance of Calcium]]; PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]]; Ruthenium Red inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]]; Ruthenium Red inhibits the reaction [Sodium affects the reaction [TRPV1 protein results in increased abundance of Calcium]]; Sodium affects the reaction [TRPV1 protein results in increased abundance of Calcium]; TRPV1 promotes the reaction [Capsaicin results in increased uptake of Calcium]
Sodium affects the reaction [TRPV1 protein results in increased abundance of Calcium]; TRPV1 protein affects the reaction [Capsaicin results in increased abundance of Calcium]; TRPV1 protein affects the reaction [Capsaicin results in increased transport of Calcium]
TRPV1 protein results in increased import of Calcium
CTD PMID:11606325 PMID:12569099 PMID:12886029 PMID:15471852 PMID:15615864 More... NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
G Trpv2 transient receptor potential cation channel, subfamily V, member 2 multiple interactions ISO [cannabichromene results in increased activity of TRPV2 protein] which results in increased uptake of Calcium; [Cannabidiol results in increased activity of TRPV2 protein] which results in increased uptake of Calcium; [cannabidiolic acid results in increased activity of TRPV2 protein] which results in increased uptake of Calcium; [cannabidivarin results in increased activity of TRPV2 protein] which results in increased uptake of Calcium CTD PMID:31096838 NCBI chr10:47,265,524...47,294,263
Ensembl chr10:47,272,931...47,294,260
JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 multiple interactions EXP
ISO
[carvacrol binds to and results in increased activity of TRPV3 protein] which results in increased transport of Calcium; [carvacrol results in increased activity of TRPV3 protein] which results in increased transport of Calcium; [Eugenol binds to and results in increased activity of TRPV3 protein] which results in increased transport of Calcium; Ruthenium Red inhibits the reaction [[carvacrol binds to and results in increased activity of TRPV3 protein] which results in increased transport of Calcium]
[carvacrol results in increased activity of TRPV3 protein] which results in increased transport of Calcium; [Eugenol results in increased activity of TRPV3 protein] which results in increased transport of Calcium
CTD PMID:16617338 PMID:20086034 NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 multiple interactions ISO TRPV4 protein promotes the reaction [phorbol-12,13-didecanoate results in increased import of Calcium]
TRPV4 protein promotes the reaction [ITGA2 protein promotes the reaction [[Dinoprostone co-treated with Serotonin] results in increased import of Calcium]]
CTD PMID:18234883 PMID:18355916 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517
JBrowse link
G Trpv5 transient receptor potential cation channel, subfamily V, member 5 increases uptake
multiple interactions
ISO TRPV5 protein results in increased uptake of Calcium
KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]]
CTD PMID:23747339 NCBI chr 4:70,536,432...70,562,743
Ensembl chr 4:70,536,440...70,562,745
JBrowse link
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 increases transport
multiple interactions
increases uptake
increases expression
ISO TRPV6 protein results in increased transport of Calcium
[[USP2 gene mutant form results in increased expression of PDZD3 protein] which results in increased activity of TRPV6 protein] which results in increased uptake of Calcium
TRPV6 protein results in increased uptake of Calcium
4-O-methyl-12-O-tetradecanoylphorbol 13-acetate inhibits the reaction [Tamoxifen inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]]; Cadmium inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]; calphostin C inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]; Gadolinium inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]; Lanthanum inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]; Tamoxifen inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]; TRPV6 protein promotes the reaction [Capsaicin results in increased abundance of Calcium]
Calcium deficiency results in increased expression of TRPV6 mRNA
CTD PMID:12584203 PMID:17292493 PMID:18648087 PMID:19996302 PMID:21146870 More... NCBI chr 4:70,507,347...70,523,013
Ensembl chr 4:70,507,348...70,523,017
JBrowse link
G Txn2 thioredoxin 2 decreases response to substance ISO TXN2 protein results in decreased susceptibility to Calcium CTD PMID:18550601 NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359
JBrowse link
G Ubb ubiquitin B affects expression EXP Calcium affects the expression of UBB mRNA CTD PMID:15913539 NCBI chr10:47,247,629...47,249,335
Ensembl chr10:47,245,637...47,249,333
JBrowse link
G Ube2d2 ubiquitin-conjugating enzyme E2D 2 affects expression EXP Calcium affects the expression of UBE2D2 mRNA CTD PMID:15913539 NCBI chr18:27,364,665...27,405,589
Ensembl chr18:27,364,303...27,406,181
JBrowse link
G Ube2g1 ubiquitin-conjugating enzyme E2G 1 affects expression
multiple interactions
EXP Calcium affects the expression of UBE2G1 mRNA
[Calcium co-treated with Calcitriol] affects the expression of UBE2G1 mRNA
CTD PMID:15913539 NCBI chr10:57,225,963...57,306,748
Ensembl chr10:57,225,952...57,308,568
JBrowse link
G Ube2i ubiquitin-conjugating enzyme E2I affects expression EXP Calcium affects the expression of UBE2I mRNA CTD PMID:15913539 NCBI chr10:14,277,749...14,294,681
Ensembl chr10:69,701,618...69,702,443
Ensembl chr10:69,701,618...69,702,443
JBrowse link
G Ubtf upstream binding transcription factor affects expression EXP Calcium affects the expression of UBTF mRNA alternative form CTD PMID:15913539 NCBI chr10:87,258,217...87,274,291
Ensembl chr10:87,258,217...87,272,969
JBrowse link
G Ucn urocortin multiple interactions EXP astressin inhibits the reaction [UCN protein inhibits the reaction [Thapsigargin results in increased uptake of Calcium]]; UCN protein inhibits the reaction [Thapsigargin results in increased uptake of Calcium] CTD PMID:17885217 NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950
JBrowse link
G Umod uromodulin affects binding ISO UMOD protein binds to Calcium CTD PMID:35263610 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302
JBrowse link
G Usp15 ubiquitin specific peptidase 15 multiple interactions ISO Calcium affects the reaction [Morphine results in increased expression of USP15 mRNA] CTD PMID:24068670 NCBI chr 7:58,756,714...58,848,778
Ensembl chr 7:58,756,872...58,848,721
JBrowse link
G Usp2 ubiquitin specific peptidase 2 multiple interactions ISO [[USP2 gene mutant form results in increased expression of PDZD3 protein] which results in increased activity of TRPV6 protein] which results in increased uptake of Calcium CTD PMID:26756164 NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of VDAC1 mRNA CTD PMID:15913539 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
G Vdr vitamin D receptor affects metabolic processing
affects abundance
affects expression
affects response to substance
ISO
EXP
VDR gene polymorphism affects the metabolism of Calcium
VDR protein affects the abundance of Calcium
Calcium affects the expression of VDR mRNA
VDR gene polymorphism affects the susceptibility to Calcium
CTD PMID:11500311 PMID:15861036 PMID:15883634 PMID:15913539 PMID:16048257 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
G Vegfa vascular endothelial growth factor A affects expression
increases abundance
multiple interactions
EXP
ISO
Calcium affects the expression of VEGFA mRNA
VEGFA protein results in increased abundance of Calcium
[VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium; TRPC6 protein promotes the reaction [[VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium]; VEGFA protein promotes the reaction [[Diglycerides results in increased activity of TRPC6 protein] which results in increased abundance of Calcium]
CTD PMID:14551041 PMID:15913539 PMID:30524369 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vim vimentin multiple interactions EXP Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of VIM protein] CTD PMID:21879721 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Vip vasoactive intestinal peptide decreases abundance EXP VIP protein results in decreased abundance of Calcium CTD PMID:21039959 NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216
JBrowse link
G Wnt5a Wnt family member 5A increases secretion
multiple interactions
increases expression
ISO Calcium results in increased secretion of WNT5A protein
CASR mutant form inhibits the reaction [Calcium results in increased expression of WNT5A protein]; WNT5A protein promotes the reaction [Calcium results in increased expression of KRT1 mRNA]; WNT5A protein promotes the reaction [Calcium results in increased expression of KRT1 protein]; WNT5A protein promotes the reaction [Calcium results in increased expression of LORICRIN mRNA]; WNT5A protein promotes the reaction [Calcium results in increased expression of LORICRIN protein]
Calcium results in increased expression of WNT5A mRNA
CTD PMID:24658506 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta affects expression EXP Calcium affects the expression of YWHAZ mRNA CTD PMID:15913539 NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
JBrowse link
atorvastatin calcium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 increases expression
decreases expression
multiple interactions
ISO Atorvastatin results in increased expression of ABCA1 mRNA
Atorvastatin results in decreased expression of ABCA1 mRNA; Atorvastatin results in decreased expression of ABCA1 protein
[Rosiglitazone co-treated with Atorvastatin] results in increased expression of ABCA1 protein
CTD PMID:15183127 PMID:16386711 PMID:25278499 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO Atorvastatin inhibits the reaction [ABCB11 protein affects the import of Taurocholic Acid]; Atorvastatin inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Atorvastatin results in decreased activity of ABCB11 protein
CTD PMID:15901796 PMID:23956101 PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases expression
decreases activity
increases transport
ISO
EXP
ABCB1 alternative form affects the reaction [CYP3A4 polymorphism affects the susceptibility to Atorvastatin]; Atorvastatin analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]
Atorvastatin results in decreased expression of ABCB1A mRNA
Atorvastatin analog results in decreased activity of ABCB1 protein
ABCB1 protein results in increased transport of Atorvastatin; ABCB1 protein results in increased transport of Atorvastatin analog
CTD PMID:10751037 PMID:15616150 PMID:19802823 PMID:24502637 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression ISO Atorvastatin results in increased expression of ABCB4 mRNA; Atorvastatin results in increased expression of ABCB4 protein CTD PMID:15986414 PMID:25278499 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases activity
multiple interactions
increases expression
ISO
EXP
Atorvastatin analog results in decreased activity of ABCC2 protein
ABCC2 protein binds to and results in increased uptake of Atorvastatin analog; Atorvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Atorvastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]
Atorvastatin results in increased expression of ABCC2 mRNA
CTD PMID:15616150 PMID:23562342 PMID:25278499 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression ISO Atorvastatin results in increased expression of ABCC3 mRNA; Atorvastatin results in increased expression of ABCC3 protein CTD PMID:15986414 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO Atorvastatin results in increased expression of ABCG2 mRNA CTD PMID:25278499 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression ISO Atorvastatin results in increased expression of ABCG5 mRNA CTD PMID:25278499 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression ISO Atorvastatin results in increased expression of ABCG8 mRNA CTD PMID:25278499 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
JBrowse link
G Acacb acetyl-CoA carboxylase beta increases expression
multiple interactions
EXP Atorvastatin results in increased expression of ACACB mRNA
Mevalonic Acid inhibits the reaction [Atorvastatin results in increased expression of ACACB mRNA]
CTD PMID:12056585 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
JBrowse link
G Ace angiotensin I converting enzyme decreases expression EXP Atorvastatin results in decreased expression of ACE mRNA CTD PMID:23390189 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ace2 angiotensin I converting enzyme 2 increases expression EXP Atorvastatin results in increased expression of ACE2 mRNA CTD PMID:23390189 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions EXP Atorvastatin inhibits the reaction [Fructose results in decreased expression of ACOX1 mRNA] CTD PMID:21122807 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of ACTA2 protein] CTD PMID:34939712 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Adam12 ADAM metallopeptidase domain 12 decreases expression ISO Atorvastatin results in decreased expression of ADAM12 protein CTD PMID:18360054 NCBI chr 1:188,686,984...189,014,206
Ensembl chr 1:188,686,989...189,020,667
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 decreases expression ISO Atorvastatin results in decreased expression of ADAM17 protein CTD PMID:18360054 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression
increases expression
ISO Atorvastatin results in decreased expression of ADIPOQ protein
Atorvastatin results in increased expression of ADIPOQ protein
CTD PMID:19651449 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Agt angiotensinogen multiple interactions EXP Atorvastatin inhibits the reaction [AGT protein results in decreased expression of SOD1 protein]; Atorvastatin inhibits the reaction [AGT protein results in increased abundance of Malondialdehyde]; Atorvastatin inhibits the reaction [AGT protein results in increased activity of MAPK1 protein]; Atorvastatin inhibits the reaction [AGT protein results in increased activity of MAPK3 protein]; Atorvastatin inhibits the reaction [AGT protein results in increased expression of NOX1 protein] CTD PMID:19451411 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation
increases phosphorylation
ISO
EXP
Atorvastatin inhibits the reaction [Homocysteine results in decreased phosphorylation of AKT1 protein]
[Atorvastatin co-treated with Celecoxib] results in decreased phosphorylation of AKT1 protein; Atorvastatin results in decreased expression of and results in decreased phosphorylation of AKT1 protein
Atorvastatin results in decreased phosphorylation of AKT1 protein
Atorvastatin results in increased phosphorylation of AKT1 protein
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of AKT1 protein]; coenzyme Q10 inhibits the reaction [Atorvastatin results in decreased phosphorylation of AKT1 protein]
CTD PMID:18172863 PMID:19526287 PMID:20305681 PMID:27345130 PMID:27815113 More... NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Angpt2 angiopoietin 2 increases expression ISO Atorvastatin results in increased expression of ANGPT2 mRNA CTD PMID:16410222 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804
JBrowse link
G Apob apolipoprotein B multiple interactions
decreases secretion
decreases expression
ISO
EXP
Atorvastatin results in decreased expression of and results in decreased secretion of APOB protein
Atorvastatin inhibits the reaction [Fructose results in increased expression of APOB protein]
Atorvastatin results in decreased secretion of APOB protein
Atorvastatin results in decreased expression of APOB protein
CTD PMID:9512650 PMID:10357840 PMID:11728391 PMID:12065722 PMID:12172771 More... NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Apoe apolipoprotein E decreases expression
multiple interactions
ISO Atorvastatin results in decreased expression of APOE mRNA; Atorvastatin results in decreased expression of APOE protein
Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the activity of GPT protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of FTH1 protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of GPX4 protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of HMOX1 protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of NFE2L2 protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of TFRC protein]
[Bezafibrate co-treated with Enalapril co-treated with Dipyridamole co-treated with Atorvastatin co-treated with Valsartan] results in decreased expression of APOE protein
CTD PMID:16386711 PMID:19603250 PMID:32976958 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO Atorvastatin inhibits the reaction [APP protein results in decreased expression of SLC1A2 protein]; Atorvastatin inhibits the reaction [APP protein results in decreased expression of SLC1A3 protein] CTD PMID:20816828 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions EXP [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein] CTD PMID:34939712 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atg5 autophagy related 5 multiple interactions
increases response to substance
ISO ATG5 mutant form promotes the reaction [Atorvastatin results in increased cleavage of CASP3 protein]; ATG5 mutant form promotes the reaction [Atorvastatin results in increased cleavage of PARP1 protein]
ATG5 results in increased susceptibility to Atorvastatin
CTD PMID:20876807 NCBI chr20:47,798,222...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO Atorvastatin results in increased expression of BAK1 protein CTD PMID:19935899 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Atorvastatin results in increased expression of BAX protein CTD PMID:19935899 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO
EXP
Atorvastatin results in decreased expression of BCL2 mRNA; Atorvastatin results in decreased expression of BCL2 protein
[Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of BCL2 protein]
RHOA mutant form inhibits the reaction [Atorvastatin results in decreased expression of BCL2 protein]
CTD PMID:16470222 PMID:32259528 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Becn1 beclin 1 increases expression ISO Atorvastatin results in increased expression of BECN1 protein CTD PMID:20876807 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression ISO Atorvastatin results in increased expression of BGLAP mRNA CTD PMID:17252541 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions EXP Atorvastatin results in decreased expression of and results in increased cleavage of BID protein; Mevalonic Acid inhibits the reaction [Atorvastatin results in decreased expression of and results in increased cleavage of BID protein]; U 0126 inhibits the reaction [Atorvastatin results in decreased expression of and results in increased cleavage of BID protein] CTD PMID:18339080 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression EXP Atorvastatin results in decreased expression of BIRC5 mRNA; Atorvastatin results in decreased expression of BIRC5 protein CTD PMID:17372815 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bmp2 bone morphogenetic protein 2 increases expression
increases secretion
ISO Atorvastatin results in increased expression of BMP2 mRNA
Atorvastatin results in increased secretion of BMP2 protein
CTD PMID:16470222 PMID:17252541 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G C3 complement C3 multiple interactions EXP [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased activity of C3 protein modified form] CTD PMID:20946910 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Casp1 caspase 1 multiple interactions EXP [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CASP1 protein] CTD PMID:34939712 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 increases activity
decreases activity
multiple interactions
increases cleavage
ISO
EXP
Atorvastatin results in increased activity of CASP3 protein
Atorvastatin results in decreased activity of CASP3 protein
[Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased activity of CASP3 protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased activity of CASP3 protein]; U 0126 inhibits the reaction [Atorvastatin results in increased activity of CASP3 protein]
Atorvastatin results in increased cleavage of CASP3 protein
[PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the cleavage of CASP3 protein; ATG5 mutant form promotes the reaction [Atorvastatin results in increased cleavage of CASP3 protein]; Atorvastatin inhibits the reaction [Homocysteine results in increased activity of CASP3 protein]
[Atorvastatin co-treated with Celecoxib] results in increased cleavage of and results in increased activity of CASP3 protein; bafilomycin A1 promotes the reaction [Atorvastatin results in increased cleavage of CASP3 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin results in increased activity of CASP3 protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased activity of CASP3 protein]; RHOA protein inhibits the reaction [Atorvastatin results in increased activity of CASP3 protein]
CTD PMID:16470222 PMID:18172863 PMID:18339080 PMID:19429019 PMID:20305681 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions
increases activity
ISO
EXP
[Atorvastatin co-treated with Celecoxib] results in increased cleavage of CASP8 protein
[Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased activity of CASP8 protein]; [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased expression of CASP8 protein]
Atorvastatin results in increased activity of CASP8 protein
CTD PMID:15705602 PMID:18172863 PMID:20946910 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
ISO
EXP
[Atorvastatin co-treated with Celecoxib] results in increased cleavage of CASP9 protein
Mevalonic Acid inhibits the reaction [Atorvastatin results in increased activity of CASP9 protein]; U 0126 inhibits the reaction [Atorvastatin results in increased activity of CASP9 protein]
CTD PMID:15705602 PMID:16470222 PMID:18172863 PMID:18339080 PMID:29630879 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions
increases activity
EXP
ISO
Atorvastatin inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]
Atorvastatin results in increased activity of CAT protein
CTD PMID:17479860 PMID:25218292 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases expression
ISO
EXP
Atorvastatin inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Atorvastatin results in decreased expression of and results in decreased secretion of CCL2 protein; Mevalonic Acid inhibits the reaction [Atorvastatin inhibits the reaction [TNF results in increased expression of CCL2 mRNA]]; Mevalonic Acid inhibits the reaction [Atorvastatin results in decreased expression of CCL2 mRNA]
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CCL2 protein]; Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of CCL2 protein]
CTD PMID:12117737 PMID:25058445 PMID:34939712 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cd14 CD14 molecule decreases expression ISO Atorvastatin results in decreased expression of CD14 protein CTD PMID:18333374 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd36 CD36 molecule multiple interactions ISO
EXP
Atorvastatin inhibits the reaction [Rosiglitazone results in increased expression of CD36 mRNA]; Atorvastatin inhibits the reaction [Rosiglitazone results in increased expression of CD36 protein]
[Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of CD36 protein]
CTD PMID:15183127 PMID:16386711 PMID:32259528 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cd40 CD40 molecule decreases expression ISO Atorvastatin results in decreased expression of CD40 protein CTD PMID:16387846 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd40lg CD40 ligand decreases expression ISO Atorvastatin results in decreased expression of CD40LG protein CTD PMID:16368305 PMID:19171469 NCBI chr  X:135,127,119...135,138,302
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Cd83 CD83 molecule decreases expression ISO Atorvastatin results in decreased expression of CD83 protein CTD PMID:16387846 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
JBrowse link
G Cd86 CD86 molecule decreases expression ISO Atorvastatin results in decreased expression of CD86 protein CTD PMID:16387846 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdh1 cadherin 1 multiple interactions EXP [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of CDH1 protein] CTD PMID:34939712 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO [Atorvastatin co-treated with Celecoxib] results in increased expression of CDKN1A protein; CDKN1A protein mutant form inhibits the reaction [Atorvastatin results in increased cleavage of PARP1 protein]
Atorvastatin results in increased expression of CDKN1A protein
CTD PMID:18172863 PMID:20876807 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
increases expression
ISO [Atorvastatin co-treated with Celecoxib] results in increased expression of CDKN1B protein
Atorvastatin results in increased expression of CDKN1B protein
CTD PMID:16470222 PMID:18172863 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO Atorvastatin inhibits the reaction [Sodium Glutamate results in increased phosphorylation of CHUK protein] CTD PMID:19800637 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Clcn1 chloride voltage-gated channel 1 decreases expression EXP Atorvastatin results in decreased expression of CLCN1 protein CTD PMID:27377005 NCBI chr 4:71,171,949...71,201,483
Ensembl chr 4:71,172,547...71,199,984
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Atorvastatin results in increased expression of COL1A1 mRNA CTD PMID:17252541 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression
multiple interactions
EXP Atorvastatin results in increased expression of CPT1A mRNA
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Atorvastatin results in increased expression of CPT1A mRNA]
CTD PMID:19053045 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Crp C-reactive protein multiple interactions
decreases expression
ISO
EXP
[Atorvastatin co-treated with Amlodipine] results in decreased expression of CRP protein; Atorvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of CRP mRNA]; Atorvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of CRP protein]
Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of CRP protein]
Atorvastatin results in decreased expression of CRP protein
CTD PMID:16025360 PMID:16360360 PMID:17673219 PMID:18389332 PMID:21584495 More... NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cs citrate synthase increases expression
multiple interactions
EXP Atorvastatin results in increased expression of CS mRNA
Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of CS mRNA]
CTD PMID:21775390 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of CSF2 mRNA]; Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of CSF2 protein]; Atorvastatin inhibits the reaction [Particulate Matter results in increased expression of CSF2 mRNA]; Atorvastatin inhibits the reaction [Particulate Matter results in increased expression of CSF2 protein] CTD PMID:19482827 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression EXP Atorvastatin results in decreased expression of CXCL10 CTD PMID:15831368 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions EXP Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of CYBA mRNA] CTD PMID:25218292 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cycs cytochrome c, somatic multiple interactions EXP [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of CYCS protein] CTD PMID:32259528 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 affects expression EXP Atorvastatin affects the expression of CYP11A1 mRNA CTD PMID:29574565 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 increases expression EXP Atorvastatin results in increased expression of CYP17A1 mRNA CTD PMID:29574565 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression EXP Atorvastatin results in increased expression of CYP19A1 mRNA CTD PMID:29574565 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 increases expression EXP Atorvastatin results in increased expression of CYP21A2 mRNA CTD PMID:29574565 NCBI chr20:4,020,217...4,026,923
Ensembl chr20:4,023,767...4,026,923
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression
increases expression
ISO Atorvastatin results in decreased expression of CYP27A1 mRNA; Atorvastatin results in decreased expression of CYP27A1 protein
Atorvastatin results in increased expression of CYP27A1 mRNA
CTD PMID:16386711 PMID:25278499 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression ISO Atorvastatin results in increased expression of CYP2B10 mRNA; Atorvastatin results in increased expression of CYP2B10 protein CTD PMID:15986414 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Atorvastatin results in increased expression of CYP2B6 mRNA CTD PMID:15802384 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 increases expression ISO Atorvastatin results in increased expression of CYP39A1 mRNA CTD PMID:25278499 NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases expression
affects response to substance
increases metabolic processing
multiple interactions
affects metabolic processing
decreases activity
increases expression
EXP
ISO
Atorvastatin results in decreased expression of CYP3A4 mRNA; Atorvastatin results in decreased expression of CYP3A4 protein
CYP3A4 polymorphism affects the susceptibility to Atorvastatin
CYP3A4 protein results in increased metabolism of Atorvastatin
ABCB1 alternative form affects the reaction [CYP3A4 polymorphism affects the susceptibility to Atorvastatin]; Atorvastatin inhibits the reaction [CYP3A4 protein affects the metabolism of Midazolam]
CYP3A4 protein affects the metabolism of Atorvastatin
Atorvastatin results in decreased activity of CYP3A4 protein
Atorvastatin results in increased expression of CYP3A4 protein
Atorvastatin promotes the reaction [Berberine results in decreased activity of CYP3A4 protein]; Berberine promotes the reaction [Atorvastatin results in decreased activity of CYP3A4 protein]; Berberine promotes the reaction [Atorvastatin results in decreased expression of CYP3A4 mRNA]; Berberine promotes the reaction [Atorvastatin results in decreased expression of CYP3A4 protein]
CTD PMID:15963098 PMID:16011971 PMID:16029222 PMID:18528690 PMID:18846481 More... NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 multiple interactions EXP [Dietary Fats co-treated with Atorvastatin] results in increased expression of CYP3A23-3A1 protein CTD PMID:26616219 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases expression
multiple interactions
ISO
EXP
Atorvastatin results in increased expression of CYP7A1 mRNA
Atorvastatin inhibits the reaction [Dietary Fats results in decreased expression of CYP7A1 mRNA]
CTD PMID:25278499 PMID:32048413 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 decreases expression ISO Atorvastatin results in decreased expression of CYP7B1 mRNA CTD PMID:25278499 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
JBrowse link
G Dcx doublecortin increases expression EXP Atorvastatin results in increased expression of DCX protein CTD PMID:15255259 NCBI chr  X:107,430,767...107,573,612
Ensembl chr  X:107,430,767...107,507,476
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 increases expression
multiple interactions
increases activity
EXP Atorvastatin results in increased expression of DGAT1 mRNA
Mevalonic Acid inhibits the reaction [Atorvastatin results in increased activity of DGAT1 protein]
CTD PMID:12056585 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Edn1 endothelin 1 decreases expression ISO Atorvastatin results in decreased expression of EDN1 protein CTD PMID:16360360 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A multiple interactions
decreases expression
EXP Atorvastatin promotes the reaction [Losartan results in decreased expression of EDNRA mRNA]; Losartan promotes the reaction [Atorvastatin results in decreased expression of EDNRA mRNA] CTD PMID:23091284 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO Atorvastatin inhibits the reaction [Phenylephrine results in increased expression of and results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:18360054 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases response to substance
ISO EIF2AK3 mutant form inhibits the reaction [Atorvastatin results in increased phosphorylation of EIF2S1 protein]
EIF2AK3 results in increased susceptibility to Atorvastatin
CTD PMID:20876807 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions
increases phosphorylation
ISO 4-phenylbutyric acid inhibits the reaction [Atorvastatin results in increased phosphorylation of EIF2S1 protein]; EIF2AK3 mutant form inhibits the reaction [Atorvastatin results in increased phosphorylation of EIF2S1 protein] CTD PMID:20876807 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Epb41 erythrocyte membrane protein band 4.1 multiple interactions EXP [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in decreased expression of EPB41 protein] CTD PMID:20946910 NCBI chr 5:144,110,010...144,264,037
Ensembl chr 5:144,111,906...144,237,821
JBrowse link
G F2 coagulation factor II decreases activity ISO Atorvastatin results in decreased activity of F2 protein CTD PMID:16907931 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F5 coagulation factor V decreases activity ISO Atorvastatin results in decreased activity of F5 protein CTD PMID:16907931 NCBI chr13:76,513,463...76,583,106
Ensembl chr13:76,513,255...76,582,317
JBrowse link
G Fadd Fas associated via death domain multiple interactions EXP [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased expression of FADD protein] CTD PMID:20946910 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fas Fas cell surface death receptor affects expression EXP Atorvastatin affects the expression of FAS mRNA; Atorvastatin affects the expression of FAS protein CTD PMID:17372815 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand multiple interactions
increases expression
EXP
ISO
[Atorvastatin co-treated with Acetylcysteine] inhibits the reaction [sodium arsenite results in increased expression of FASLG protein]
Atorvastatin results in increased expression of FASLG protein modified form
Atorvastatin inhibits the reaction [TNF protein results in decreased expression of and results in decreased secretion of FASLG protein modified form]
CTD PMID:15063428 PMID:20946910 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fasn fatty acid synthase increases expression
multiple interactions
ISO
EXP
Atorvastatin results in increased expression of FASN mRNA
[Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of FASN protein]; Atorvastatin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of FASN protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased expression of FASN mRNA]
CTD PMID:11728391 PMID:12056585 PMID:32259528 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbxo32 F-box protein 32 increases expression EXP Atorvastatin results in increased expression of FBXO32 mRNA CTD PMID:27377005 NCBI chr 7:89,731,626...89,764,761
Ensembl chr 7:89,730,232...89,765,436
JBrowse link
G Fgf19 fibroblast growth factor 19 decreases expression ISO Atorvastatin results in decreased expression of FGF15 mRNA CTD PMID:25278499 NCBI chr 1:200,056,656...200,059,944
Ensembl chr 1:200,056,644...200,060,287
JBrowse link
G Foxo1 forkhead box O1 decreases phosphorylation ISO Atorvastatin results in decreased phosphorylation of FOXO1 protein CTD PMID:33034787 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of FTH1 protein] CTD PMID:32976958 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO [Atorvastatin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA CTD PMID:24204015 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
JBrowse link
G Gck glucokinase decreases expression
multiple interactions
ISO
EXP
Atorvastatin results in decreased expression of GCK protein
NR1I2 protein promotes the reaction [Atorvastatin results in decreased expression of GCK protein]
CTD PMID:26616219 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions EXP Atorvastatin promotes the reaction [dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of GJA1 protein]] CTD PMID:34939712 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gng3 G protein subunit gamma 3 multiple interactions
affects localization
EXP [Isoproterenol co-treated with Atorvastatin] affects the localization of GNG3 protein
Atorvastatin affects the localization of GNG3 protein
CTD PMID:19136528 NCBI chr 1:205,731,837...205,733,603
Ensembl chr 1:205,731,837...205,733,603
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions EXP Atorvastatin inhibits the reaction [Streptozocin results in increased secretion of GOT1 protein] CTD PMID:30657622 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial multiple interactions EXP Atorvastatin inhibits the reaction [Fructose results in increased expression of GPAM mRNA] CTD PMID:19053045 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO
EXP
[Atorvastatin co-treated with Ciprofloxacin] results in increased expression of GPT protein; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the activity of GPT protein]; Buthionine Sulfoximine promotes the reaction [[Atorvastatin co-treated with Ciprofloxacin] results in increased expression of GPT protein]
[Atorvastatin co-treated with triptolide] results in increased expression of GPT protein; [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of GPT protein]; Atorvastatin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of GPT protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased secretion of GPT protein]
CTD PMID:29679711 PMID:30657622 PMID:32259528 PMID:32976958 PMID:33600922 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions ISO Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of GPX4 protein] CTD PMID:32976958 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Hbegf heparin-binding EGF-like growth factor decreases expression ISO Atorvastatin results in decreased expression of HBEGF protein CTD PMID:18360054 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
affects binding
increases expression
increases activity
ISO
EXP
Atorvastatin results in increased expression of and results in increased activity of HMGCR protein
Atorvastatin binds to HMGCR protein
Atorvastatin inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in decreased expression of HMGCR mRNA]; Atorvastatin inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in increased activity of HMGCR protein]; Atorvastatin inhibits the reaction [Dietary Fats results in increased expression of HMGCR mRNA]; Atorvastatin results in increased expression of and results in increased activity of HMGCR protein; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased activity of HMGCR protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased expression of HMGCR mRNA]
CTD PMID:9512650 PMID:10357840 PMID:12056585 PMID:12065722 PMID:12612140 More... NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO
EXP
Atorvastatin results in increased expression of HMOX1 mRNA
Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of HMOX1 protein]
[Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; Atorvastatin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]
CTD PMID:16410222 PMID:32259528 PMID:32976958 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha multiple interactions EXP Atorvastatin inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in decreased expression of HNF4A mRNA] CTD PMID:30273964 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression
ISO
EXP
Atorvastatin inhibits the reaction [TNF results in increased expression of ICAM1]
Atorvastatin results in increased expression of ICAM1 protein
Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of ICAM1 protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]
CTD PMID:12615677 PMID:17589825 PMID:19171469 PMID:25058445 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO Atorvastatin inhibits the reaction [Sodium Glutamate results in increased phosphorylation of IKBKB protein] CTD PMID:19800637 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Il12a interleukin 12A decreases expression ISO Atorvastatin results in decreased expression of IL12A mRNA CTD PMID:12492458 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of IL1B mRNA]; Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of IL1B protein]; Atorvastatin inhibits the reaction [Particulate Matter results in increased expression of IL1B mRNA]; Atorvastatin inhibits the reaction [Particulate Matter results in increased expression of IL1B protein]
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of IL1B protein]; Atorvastatin inhibits the reaction [Dietary Fats results in increased expression of IL1B protein]; Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of IL1B protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]
CTD PMID:17589825 PMID:19482827 PMID:25058445 PMID:32048413 PMID:34939712 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha affects expression ISO Atorvastatin affects the expression of IL2RA protein CTD PMID:16387846 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697