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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:bornane monoterpenoid
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Accession:CHEBI:22912 term browser browse the term
Synonyms:related_synonym: bornane monoterpenoids


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(1S)-bornane-2,3-dione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase increases phosphorylation ISO camphorquinone results in increased phosphorylation of ATM protein CTD PMID:26658076 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO camphorquinone results in decreased expression of CCNB1 mRNA; camphorquinone results in decreased expression of CCNB1 protein CTD PMID:26658076 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO camphorquinone results in decreased expression of CDC25C mRNA; camphorquinone results in decreased expression of CDC25C protein CTD PMID:26658076 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO camphorquinone results in decreased expression of CDK1 mRNA; camphorquinone results in decreased expression of CDK1 protein CTD PMID:26658076 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression		 ISO Acetylcysteine inhibits the reaction [camphorquinone results in increased expression of CDKN1A protein]
camphorquinone results in increased expression of CDKN1A mRNA; camphorquinone results in increased expression of CDKN1A protein		 CTD PMID:26658076 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation ISO camphorquinone results in increased phosphorylation of CHEK2 protein CTD PMID:26658076 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Dhrs11 dehydrogenase/reductase 11 increases reduction ISO DHRS11 protein results in increased reduction of camphorquinone CTD PMID:30926317 NCBI chr10:69,698,214...69,708,294
Ensembl chr10:69,698,214...69,708,295 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO camphorquinone results in increased expression of GADD45A protein CTD PMID:26658076 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression		 ISO Acetylcysteine inhibits the reaction [camphorquinone results in increased expression of HMOX1 protein]
camphorquinone results in increased expression of HMOX1 mRNA; camphorquinone results in increased expression of HMOX1 protein		 CTD PMID:26658076 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO camphorquinone results in increased phosphorylation of MAPK1 protein CTD PMID:26658076 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO camphorquinone results in increased phosphorylation of MAPK3 protein CTD PMID:26658076 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions		 ISO camphorquinone results in increased expression of PTGS2 mRNA; camphorquinone results in increased expression of PTGS2 protein
U 0126 inhibits the reaction [camphorquinone results in increased expression of PTGS2 protein]		 CTD PMID:26658076 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Tp53 tumor protein p53 increases phosphorylation ISO camphorquinone results in increased phosphorylation of TP53 protein CTD PMID:26658076 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
(R)-camphor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a2 collagen type I alpha 2 chain affects expression ISO Camphor analog affects the expression of COL1A2 mRNA CTD PMID:24704097 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases activity EXP Camphor results in decreased activity of CYP2B1 protein CTD PMID:9242356 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO Camphor inhibits the reaction [CYP2B6 protein results in increased hydrolysis of Bupropion] CTD PMID:18611395 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Camphor binds to and results in increased activity of ESR1 protein CTD PMID:27633901 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions ISO Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864 		JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions ISO Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions ISO Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,376,805...26,463,680
Ensembl chr10:26,374,694...26,464,346 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO Camphor inhibits the reaction [cinnamaldehyde results in increased activity of MPO protein] CTD PMID:21466812 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Pgr progesterone receptor multiple interactions ISO Camphor binds to and results in decreased activity of PGR protein CTD PMID:27633901 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Runx2 RUNX family transcription factor 2 affects expression ISO Camphor analog affects the expression of RUNX2 mRNA CTD PMID:24704097 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Sparc secreted protein acidic and cysteine rich affects expression ISO Camphor analog affects the expression of SPARC mRNA CTD PMID:24704097 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions EXP Lidocaine promotes the reaction [Camphor results in increased activity of TRPV1 protein] CTD PMID:18172555 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 increases activity
multiple interactions		 ISO Camphor results in increased activity of TRPV3 protein
isopentenyl pyrophosphate inhibits the reaction [Camphor results in increased activity of TRPV3 protein]		 CTD PMID:21353389 NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296 		JBrowse link
bornane-2,3-dione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO camphoroquinone inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein] CTD PMID:11985887 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
camphor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a2 collagen type I alpha 2 chain affects expression ISO Camphor analog affects the expression of COL1A2 mRNA CTD PMID:24704097 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases activity EXP Camphor results in decreased activity of CYP2B1 protein CTD PMID:9242356 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO Camphor inhibits the reaction [CYP2B6 protein results in increased hydrolysis of Bupropion] CTD PMID:18611395 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Camphor binds to and results in increased activity of ESR1 protein CTD PMID:27633901 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions ISO Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864 		JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions ISO Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions ISO Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,376,805...26,463,680
Ensembl chr10:26,374,694...26,464,346 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO Camphor inhibits the reaction [cinnamaldehyde results in increased activity of MPO protein] CTD PMID:21466812 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Pgr progesterone receptor multiple interactions ISO Camphor binds to and results in decreased activity of PGR protein CTD PMID:27633901 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Runx2 RUNX family transcription factor 2 affects expression ISO Camphor analog affects the expression of RUNX2 mRNA CTD PMID:24704097 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Sparc secreted protein acidic and cysteine rich affects expression ISO Camphor analog affects the expression of SPARC mRNA CTD PMID:24704097 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions EXP Lidocaine promotes the reaction [Camphor results in increased activity of TRPV1 protein] CTD PMID:18172555 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 increases activity
multiple interactions		 ISO Camphor results in increased activity of TRPV3 protein
isopentenyl pyrophosphate inhibits the reaction [Camphor results in increased activity of TRPV3 protein]		 CTD PMID:21353389 NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19795
    chemical entity 19795
      atom 19794
        nonmetal atom 19681
          carbon atom 19604
            organic molecular entity 19604
              isoprenoid 12723
                terpenoid 12293
                  monoterpenoid 1224
                    bornane monoterpenoid 27
                      (+)-bornyl diphosphate 0
                      (-)-bornyl diphosphate 0
                      2-methylisoborneol 0
                      5-hydroxycamphor + 0
                      6-hydroxycamphor + 0
                      alpha-santalol 0
                      bornane-2,3-dione + 14
                      bornane-2,5-dione + 0
                      borneol + 0
                      camphor + 13
                      isobornyl formate 0
                      norbornane monoterpenoid + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19795
    subatomic particle 19794
      composite particle 19794
        hadron 19794
          baryon 19794
            nucleon 19794
              atomic nucleus 19794
                atom 19794
                  main group element atom 19693
                    main group molecular entity 19693
                      s-block molecular entity 19474
                        hydrogen molecular entity 19466
                          hydrides 18830
                            organic hydride 18346
                              organic fundamental parent 18346
                                hydrocarbon 18057
                                  terpene 12723
                                    terpenoid 12293
                                      monoterpenoid 1224
                                        bornane monoterpenoid 27
                                          (+)-bornyl diphosphate 0
                                          (-)-bornyl diphosphate 0
                                          2-methylisoborneol 0
                                          5-hydroxycamphor + 0
                                          6-hydroxycamphor + 0
                                          alpha-santalol 0
                                          bornane-2,3-dione + 14
                                          bornane-2,5-dione + 0
                                          borneol + 0
                                          camphor + 13
                                          isobornyl formate 0
                                          norbornane monoterpenoid + 0
paths to the root