CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: bornane monoterpenoid
Accession: CHEBI:22912
browse the term
Synonyms: related_synonym: bornane monoterpenoids
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Atm
ATM serine/threonine kinase
increases phosphorylation
ISO
camphorquinone results in increased phosphorylation of ATM protein
CTD
PMID:26658076
NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
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Ccnb1
cyclin B1
decreases expression
ISO
camphorquinone results in decreased expression of CCNB1 mRNA; camphorquinone results in decreased expression of CCNB1 protein
CTD
PMID:26658076
NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
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Cdc25c
cell division cycle 25C
decreases expression
ISO
camphorquinone results in decreased expression of CDC25C mRNA; camphorquinone results in decreased expression of CDC25C protein
CTD
PMID:26658076
NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
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Cdk1
cyclin-dependent kinase 1
decreases expression
ISO
camphorquinone results in decreased expression of CDK1 mRNA; camphorquinone results in decreased expression of CDK1 protein
CTD
PMID:26658076
NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
multiple interactions increases expression
ISO
Acetylcysteine inhibits the reaction [camphorquinone results in increased expression of CDKN1A protein] camphorquinone results in increased expression of CDKN1A mRNA; camphorquinone results in increased expression of CDKN1A protein
CTD
PMID:26658076
NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
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Chek2
checkpoint kinase 2
increases phosphorylation
ISO
camphorquinone results in increased phosphorylation of CHEK2 protein
CTD
PMID:26658076
NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
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Dhrs11
dehydrogenase/reductase 11
increases reduction
ISO
DHRS11 protein results in increased reduction of camphorquinone
CTD
PMID:30926317
NCBI chr10:72,144,042...72,153,496
Ensembl chr10:72,144,042...72,153,375
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Gadd45a
growth arrest and DNA-damage-inducible, alpha
increases expression
ISO
camphorquinone results in increased expression of GADD45A protein
CTD
PMID:26658076
NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
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Hmox1
heme oxygenase 1
multiple interactions increases expression
ISO
Acetylcysteine inhibits the reaction [camphorquinone results in increased expression of HMOX1 protein] camphorquinone results in increased expression of HMOX1 mRNA; camphorquinone results in increased expression of HMOX1 protein
CTD
PMID:26658076
NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
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Mapk1
mitogen activated protein kinase 1
increases phosphorylation
ISO
camphorquinone results in increased phosphorylation of MAPK1 protein
CTD
PMID:26658076
NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
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Mapk3
mitogen activated protein kinase 3
increases phosphorylation
ISO
camphorquinone results in increased phosphorylation of MAPK3 protein
CTD
PMID:26658076
NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
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Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression multiple interactions
ISO
camphorquinone results in increased expression of PTGS2 mRNA; camphorquinone results in increased expression of PTGS2 protein U 0126 inhibits the reaction [camphorquinone results in increased expression of PTGS2 protein]
CTD
PMID:26658076
NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
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Tp53
tumor protein p53
increases phosphorylation
ISO
camphorquinone results in increased phosphorylation of TP53 protein
CTD
PMID:26658076
NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
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Col1a2
collagen type I alpha 2 chain
affects expression
ISO
Camphor analog affects the expression of COL1A2 mRNA
CTD
PMID:24704097
NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
G
Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
decreases activity
EXP
Camphor results in decreased activity of CYP2B1 protein
CTD
PMID:9242356
NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
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Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
multiple interactions
ISO
Camphor inhibits the reaction [CYP2B6 protein results in increased hydrolysis of Bupropion]
CTD
PMID:18611395
NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
G
Esr1
estrogen receptor 1
multiple interactions
ISO
Camphor binds to and results in increased activity of ESR1 protein
CTD
PMID:27633901
NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
G
Gabra1
gamma-aminobutyric acid type A receptor subunit alpha 1
multiple interactions
ISO
Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
CTD
PMID:15588619
NCBI chr10:27,310,718...27,371,802
Ensembl chr10:27,310,725...27,366,665
G
Gabrb2
gamma-aminobutyric acid type A receptor subunit beta 2
multiple interactions
ISO
Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
CTD
PMID:15588619
NCBI chr10:27,973,694...28,193,072
Ensembl chr10:27,973,681...28,187,565
G
Gabrg2
gamma-aminobutyric acid type A receptor subunit gamma 2
multiple interactions
ISO
Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
CTD
PMID:15588619
NCBI chr10:27,090,913...27,179,786
Ensembl chr10:27,092,827...27,179,900
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Mpo
myeloperoxidase
multiple interactions
ISO
Camphor inhibits the reaction [cinnamic aldehyde results in increased activity of MPO protein]
CTD
PMID:21466812
NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
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Pgr
progesterone receptor
multiple interactions
ISO
Camphor binds to and results in decreased activity of PGR protein
CTD
PMID:27633901
NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
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Runx2
RUNX family transcription factor 2
affects expression
ISO
Camphor analog affects the expression of RUNX2 mRNA
CTD
PMID:24704097
NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
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Sparc
secreted protein acidic and cysteine rich
affects expression
ISO
Camphor analog affects the expression of SPARC mRNA
CTD
PMID:24704097
NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
G
Trpv1
transient receptor potential cation channel, subfamily V, member 1
multiple interactions
EXP
Lidocaine promotes the reaction [Camphor results in increased activity of TRPV1 protein]
CTD
PMID:18172555
NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
G
Trpv3
transient receptor potential cation channel, subfamily V, member 3
increases activity multiple interactions
ISO
Camphor results in increased activity of TRPV3 protein isopentenyl pyrophosphate inhibits the reaction [Camphor results in increased activity of TRPV3 protein]
CTD
PMID:21353389
NCBI chr10:59,829,755...59,863,780
Ensembl chr10:59,831,241...59,860,987
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Ar
androgen receptor
multiple interactions
ISO
camphoroquinone inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]
CTD
PMID:11985887
NCBI chr X:67,656,253...67,828,998
Ensembl chr X:67,656,253...67,829,026
G
Col1a2
collagen type I alpha 2 chain
affects expression
ISO
Camphor analog affects the expression of COL1A2 mRNA
CTD
PMID:24704097
NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
G
Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
decreases activity
EXP
Camphor results in decreased activity of CYP2B1 protein
CTD
PMID:9242356
NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
G
Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
multiple interactions
ISO
Camphor inhibits the reaction [CYP2B6 protein results in increased hydrolysis of Bupropion]
CTD
PMID:18611395
NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
G
Esr1
estrogen receptor 1
multiple interactions
ISO
Camphor binds to and results in increased activity of ESR1 protein
CTD
PMID:27633901
NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
G
Gabra1
gamma-aminobutyric acid type A receptor subunit alpha 1
multiple interactions
ISO
Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
CTD
PMID:15588619
NCBI chr10:27,310,718...27,371,802
Ensembl chr10:27,310,725...27,366,665
G
Gabrb2
gamma-aminobutyric acid type A receptor subunit beta 2
multiple interactions
ISO
Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
CTD
PMID:15588619
NCBI chr10:27,973,694...28,193,072
Ensembl chr10:27,973,681...28,187,565
G
Gabrg2
gamma-aminobutyric acid type A receptor subunit gamma 2
multiple interactions
ISO
Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
CTD
PMID:15588619
NCBI chr10:27,090,913...27,179,786
Ensembl chr10:27,092,827...27,179,900
G
Mpo
myeloperoxidase
multiple interactions
ISO
Camphor inhibits the reaction [cinnamic aldehyde results in increased activity of MPO protein]
CTD
PMID:21466812
NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
G
Pgr
progesterone receptor
multiple interactions
ISO
Camphor binds to and results in decreased activity of PGR protein
CTD
PMID:27633901
NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
G
Runx2
RUNX family transcription factor 2
affects expression
ISO
Camphor analog affects the expression of RUNX2 mRNA
CTD
PMID:24704097
NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
G
Sparc
secreted protein acidic and cysteine rich
affects expression
ISO
Camphor analog affects the expression of SPARC mRNA
CTD
PMID:24704097
NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
G
Trpv1
transient receptor potential cation channel, subfamily V, member 1
multiple interactions
EXP
Lidocaine promotes the reaction [Camphor results in increased activity of TRPV1 protein]
CTD
PMID:18172555
NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
G
Trpv3
transient receptor potential cation channel, subfamily V, member 3
increases activity multiple interactions
ISO
Camphor results in increased activity of TRPV3 protein isopentenyl pyrophosphate inhibits the reaction [Camphor results in increased activity of TRPV3 protein]
CTD
PMID:21353389
NCBI chr10:59,829,755...59,863,780
Ensembl chr10:59,831,241...59,860,987
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