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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:benzenetriol
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Accession:CHEBI:22707 term browser browse the term
Definition:A triol in which three hydroxy groups are substituted onto a benzene ring.
Synonyms:related_synonym: benzenetriols;   trihydroxybenzenes



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(-)-epigallocatechin 3-gallate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor multiple interactions EXP epigallocatechin gallate inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl affects the localization of and results in increased activity of AHR protein]; epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased activity of AHR protein]; epigallocatechin gallate inhibits the reaction [[alpha-naphthoflavone co-treated with 3,4,3',4'-tetrachlorobiphenyl] results in increased activity of AHR protein]; epigallocatechin gallate inhibits the reaction [alpha-naphthoflavone results in increased activity of AHR protein] CTD PMID:12970578 PMID:22521609 NCBI chr 9:86,511,866...86,555,950
Ensembl chr 9:86,511,369...86,555,943
JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 multiple interactions
decreases expression
EXP epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA]; epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 protein]; epigallocatechin gallate inhibits the reaction [titanium dioxide results in increased expression of CCL2 mRNA]; epigallocatechin gallate inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; HMOX1 protein promotes the reaction [epigallocatechin gallate inhibits the reaction [TNF protein results in increased expression of CCL2 protein]]
epigallocatechin gallate results in decreased expression of CCL2 mRNA
CTD PMID:20580034 PMID:22521609 PMID:23380242 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions
decreases activity
decreases expression
EXP epigallocatechin gallate inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased activity of CYP1A1 protein]; epigallocatechin gallate inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 mRNA]; epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein]; epigallocatechin gallate inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; epigallocatechin gallate inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]
epigallocatechin gallate results in decreased activity of CYP1A1 protein
epigallocatechin gallate results in decreased expression of CYP1A1 mRNA
CTD PMID:12970578 PMID:22521609 NCBI chr 7:58,802,887...58,809,155
Ensembl chr 7:58,802,887...58,809,775
JBrowse link
G GSTO1 glutathione S-transferase omega 1 multiple interactions
increases expression
EXP [epigallocatechin gallate co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of GSTO1 mRNA; NFE2L2 protein affects the reaction [epigallocatechin gallate results in increased expression of GSTO1 mRNA] CTD PMID:22521609 NCBI chr14:115,206,434...115,216,624
Ensembl chr14:115,206,188...115,216,613
JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions EXP HMOX1 protein promotes the reaction [epigallocatechin gallate inhibits the reaction [TNF protein results in increased expression of CCL2 protein]] CTD PMID:20580034
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions EXP NFE2L2 protein affects the reaction [epigallocatechin gallate results in increased expression of GSTO1 mRNA]; NFE2L2 protein affects the reaction [epigallocatechin gallate results in increased expression of NQO1 mRNA] CTD PMID:22521609 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
EXP epigallocatechin gallate results in increased expression of NQO1 mRNA
[epigallocatechin gallate co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of NQO1 mRNA; NFE2L2 protein affects the reaction [epigallocatechin gallate results in increased expression of NQO1 mRNA]
CTD PMID:22521609 NCBI chr 6:17,292,962...17,302,593
Ensembl chr 6:17,292,770...17,302,590
JBrowse link
G SLCO1A2 solute carrier organic anion transporter family member 1A2 multiple interactions EXP epigallocatechin gallate inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; epigallocatechin gallate inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; epigallocatechin gallate inhibits the reaction [SLCO1A2 protein results in increased uptake of Penicillins]; epigallocatechin gallate inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid] CTD PMID:31287969 NCBI chr 5:52,020,303...52,133,132
Ensembl chr 5:52,049,443...52,129,730
JBrowse link
G TNF tumor necrosis factor multiple interactions EXP epigallocatechin gallate inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; HMOX1 protein promotes the reaction [epigallocatechin gallate inhibits the reaction [TNF protein results in increased expression of CCL2 protein]] CTD PMID:20580034 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions
decreases expression
EXP epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA]; epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 protein]; epigallocatechin gallate inhibits the reaction [titanium dioxide results in increased expression of VCAM1 mRNA]
epigallocatechin gallate results in decreased expression of VCAM1 mRNA
CTD PMID:22521609 PMID:23380242 NCBI chr 4:117,496,914...117,511,211
Ensembl chr 4:117,496,920...117,511,222
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5066
    chemical entity 5066
      molecular entity 5065
        polyatomic entity 5045
          heteroatomic molecular entity 5014
            hydroxides 4848
              organic hydroxy compound 4780
                phenols 640
                  benzenetriol 10
                    (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + 0
                    (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one 0
                    2',4',6'-trihydroxyacetophenone + 0
                    2,3,4-trihydroxbenzophenone 0
                    2,3,4-trihydroxy-6-(hydroxymethyl)-5-methylbenzylacohol 0
                    2,3,4-trihydroxy-6-(methoxymethyl)-5-methylbenzaldehyde 0
                    2,4,5-Trihydroxytoluene 0
                    2,4,5-Trimethoxy-1-allylbenzene 0
                    2,4,5-Trimethoxytoluene 0
                    2,4,5-trihydroxyphenylacetic acid 0
                    2,4,6-trihydroxy-5-[1-(3-hydroxy-1,1,5-trimethyldecahydrocyclopropa[e]inden-5-yl)-3-methylbutyl]isophthalaldehyde 0
                    2,4,6-trihydroxybenzophenone 0
                    2,4-diacetylphloroglucinol 0
                    2,5-dihydroxy-3-phenyl-6-(3,4,5-trihydroxyphenyl)-1,4-benzoquinone 0
                    2-(3-methylbutanoyl)-4-prenylphloroglucinol 0
                    2-(4-hydroxy-3-methylbut-2-en-1-yl)-4-(3-methylbut-2-en-1-yl)benzene-1,3,5-triol 0
                    2-(4-hydroxy-3-methylbut-2-en-1-yl)benzene-1,3,5-triol 0
                    2-Chlorophloroglucinol 0
                    2-[(2E)-4-hydroxy-3-methylbut-2-en-1-yl]benzene-1,3,5-triol 0
                    2-[(3,3-dimethyloxiran-2-yl)methyl]benzene-1,3,5-triol 0
                    2-[(3,4,5-trihydroxyphenyl)methylidene]propanedinitrile 0
                    2-\{[3-methyl-3-(4-methylpent-3-en-1-yl)oxiran-2-yl]methyl\}benzene-1,3,5-triol 0
                    2-acyl-4,6-diprenylphloroglucinol + 0
                    2-acyl-4-prenylphloroglucinol + 0
                    2-acylphloroglucinol + 0
                    2-amino-4-(3,4,5-trihydroxyphenyl)buta-1,3-diene-1,1,3-tricarbonitrile 0
                    2-isobutyryl-4-prenylphloroglucinol 0
                    2-nitrobenzene-1,3,5-triol 0
                    4-hydroxy-5-(2,4,5-trihydroxyphenyl)pentanoic acid 0
                    4-hydroxy-5-(3,4,5-trihydroxyphenyl)pentanoic acid 0
                    5-(3',4',5'-trihydroxyphenyl)-gamma-valerolactone 0
                    5-[(2,4,5-trihydroxyphenyl)methyl]oxolan-2-one 0
                    5-chloro-1,2,4-trihydroxybenzene 0
                    6-Chlorobenzene-1,2,4-triol 0
                    6-[(8Z)-pentadec-8-en-1-yl]benzene-1,2,4-triol + 0
                    6-[(8Z,11Z)-heptadeca-8,11-dien-1-yl]benzene-1,2,4-triol + 0
                    6-pentadecylbenzene-1,2,4-triol + 0
                    Clostyrylpyrone A 0
                    Clostyrylpyrone B 0
                    Clostyrylpyrone C 0
                    Clostyrylpyrone D 0
                    Cytosporaquinone B 0
                    Quinolidomicin A2 0
                    Sohirnone B 0
                    Trimidox 0
                    Versicolin 0
                    allyltetramethoxybenzene 0
                    benzene-1,2,3,4,5-pentol 0
                    benzene-1,2,3,4-tetrol 0
                    benzene-1,2,4-triol 0
                    drummondin F 0
                    gallate ester + 10
                    homoeriodictyol chalcone 0
                    multifidol + 0
                    okanin 0
                    oxidopamine 0
                    phloroglucinol + 0
                    pyrogallol + 0
                    rottlerin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 5066
    subatomic particle 5057
      composite particle 5057
        hadron 5057
          baryon 5057
            nucleon 5057
              atomic nucleus 5057
                atom 5057
                  main group element atom 5026
                    p-block element atom 5023
                      chalcogen 4928
                        oxygen atom 4896
                          oxygen molecular entity 4896
                            hydroxides 4848
                              organic hydroxy compound 4780
                                polyol 4320
                                  triol 4316
                                    benzenetriol 10
                                      (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + 0
                                      (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one 0
                                      2',4',6'-trihydroxyacetophenone + 0
                                      2,3,4-trihydroxbenzophenone 0
                                      2,3,4-trihydroxy-6-(hydroxymethyl)-5-methylbenzylacohol 0
                                      2,3,4-trihydroxy-6-(methoxymethyl)-5-methylbenzaldehyde 0
                                      2,4,5-Trihydroxytoluene 0
                                      2,4,5-Trimethoxy-1-allylbenzene 0
                                      2,4,5-Trimethoxytoluene 0
                                      2,4,5-trihydroxyphenylacetic acid 0
                                      2,4,6-trihydroxy-5-[1-(3-hydroxy-1,1,5-trimethyldecahydrocyclopropa[e]inden-5-yl)-3-methylbutyl]isophthalaldehyde 0
                                      2,4,6-trihydroxybenzophenone 0
                                      2,4-diacetylphloroglucinol 0
                                      2,5-dihydroxy-3-phenyl-6-(3,4,5-trihydroxyphenyl)-1,4-benzoquinone 0
                                      2-(3-methylbutanoyl)-4-prenylphloroglucinol 0
                                      2-(4-hydroxy-3-methylbut-2-en-1-yl)-4-(3-methylbut-2-en-1-yl)benzene-1,3,5-triol 0
                                      2-(4-hydroxy-3-methylbut-2-en-1-yl)benzene-1,3,5-triol 0
                                      2-Chlorophloroglucinol 0
                                      2-[(2E)-4-hydroxy-3-methylbut-2-en-1-yl]benzene-1,3,5-triol 0
                                      2-[(3,3-dimethyloxiran-2-yl)methyl]benzene-1,3,5-triol 0
                                      2-[(3,4,5-trihydroxyphenyl)methylidene]propanedinitrile 0
                                      2-\{[3-methyl-3-(4-methylpent-3-en-1-yl)oxiran-2-yl]methyl\}benzene-1,3,5-triol 0
                                      2-acyl-4,6-diprenylphloroglucinol + 0
                                      2-acyl-4-prenylphloroglucinol + 0
                                      2-acylphloroglucinol + 0
                                      2-amino-4-(3,4,5-trihydroxyphenyl)buta-1,3-diene-1,1,3-tricarbonitrile 0
                                      2-isobutyryl-4-prenylphloroglucinol 0
                                      2-nitrobenzene-1,3,5-triol 0
                                      4-hydroxy-5-(2,4,5-trihydroxyphenyl)pentanoic acid 0
                                      4-hydroxy-5-(3,4,5-trihydroxyphenyl)pentanoic acid 0
                                      5-(3',4',5'-trihydroxyphenyl)-gamma-valerolactone 0
                                      5-[(2,4,5-trihydroxyphenyl)methyl]oxolan-2-one 0
                                      5-chloro-1,2,4-trihydroxybenzene 0
                                      6-Chlorobenzene-1,2,4-triol 0
                                      6-[(8Z)-pentadec-8-en-1-yl]benzene-1,2,4-triol + 0
                                      6-[(8Z,11Z)-heptadeca-8,11-dien-1-yl]benzene-1,2,4-triol + 0
                                      6-pentadecylbenzene-1,2,4-triol + 0
                                      Clostyrylpyrone A 0
                                      Clostyrylpyrone B 0
                                      Clostyrylpyrone C 0
                                      Clostyrylpyrone D 0
                                      Cytosporaquinone B 0
                                      Quinolidomicin A2 0
                                      Sohirnone B 0
                                      Trimidox 0
                                      Versicolin 0
                                      allyltetramethoxybenzene 0
                                      benzene-1,2,3,4,5-pentol 0
                                      benzene-1,2,3,4-tetrol 0
                                      benzene-1,2,4-triol 0
                                      drummondin F 0
                                      gallate ester + 10
                                      homoeriodictyol chalcone 0
                                      multifidol + 0
                                      okanin 0
                                      oxidopamine 0
                                      phloroglucinol + 0
                                      pyrogallol + 0
                                      rottlerin 0
paths to the root