Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:auxin
go back to main search page
Accession:CHEBI:22676 term browser browse the term
Definition:Any of a group of compounds, both naturally occurring and synthetic, that induce cell elongation in plant stems (from Greek alphaupsilonxialphanuomega, 'to grow').
Synonyms:related_synonym: auxins
 xref: Wikipedia:Auxin



show annotations for term's descendants           Sort by:
(2,4,5-trichlorophenoxy)acetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP-binding cassette, sub-family A member 7 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ABCA7 mRNA CTD PMID:18579281 NCBI chr10:79,832,328...79,851,406
Ensembl chr10:79,832,328...79,851,406
JBrowse link
G Abcb4 ATP-binding cassette, sub-family B member 4 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ABCB4 mRNA CTD PMID:9210621 NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231
JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 increases expression
multiple interactions
ISO
EXP
2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ABCC2 mRNA; 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ABCC2 protein
Alpha-Amanitin inhibits the reaction [2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ABCC2 mRNA]
CTD PMID:10377250 PMID:16426233 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Acap3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of ACAP3 mRNA CTD PMID:18579281 NCBI chr 4:155,976,332...155,991,708
Ensembl chr 4:155,976,279...155,991,708
JBrowse link
G Acer2 alkaline ceramidase 2 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of ACER2 mRNA CTD PMID:18579281 NCBI chr 4:86,792,585...86,853,059
Ensembl chr 4:86,792,633...86,853,059
JBrowse link
G Adgrb2 adhesion G protein-coupled receptor B2 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ADGRB2 mRNA CTD PMID:18579281 NCBI chr 4:129,878,566...129,916,426
Ensembl chr 4:129,878,663...129,916,426
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ADH4 mRNA CTD PMID:18579281 NCBI chr 3:138,121,217...138,138,444
Ensembl chr 3:138,121,227...138,136,653
JBrowse link
G Alpi alkaline phosphatase, intestinal decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of ALPI mRNA CTD PMID:18579281 NCBI chr 1:87,025,724...87,029,328
Ensembl chr 1:87,025,724...87,029,328
JBrowse link
G Ar androgen receptor affects binding ISO 2,4,5-Trichlorophenoxyacetic Acid binds to AR protein CTD PMID:14565775 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821
JBrowse link
G Arhgap32 Rho GTPase activating protein 32 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ARHGAP32 mRNA CTD PMID:18579281 NCBI chr 9:31,927,921...32,176,061
Ensembl chr 9:32,027,432...32,179,742
JBrowse link
G Arsg arylsulfatase G increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ARSG mRNA CTD PMID:18579281 NCBI chr11:109,364,159...109,464,156
Ensembl chr11:109,364,200...109,464,156
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of BASP1 mRNA CTD PMID:18579281 NCBI chr15:25,363,363...25,413,850
Ensembl chr15:25,363,363...25,413,850
JBrowse link
G C1qtnf4 C1q and tumor necrosis factor related protein 4 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of C1QTNF4 mRNA CTD PMID:18579281 NCBI chr 2:90,713,132...90,720,870
Ensembl chr 2:90,716,204...90,720,869
JBrowse link
G Cacnb3 calcium channel, voltage-dependent, beta 3 subunit increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of CACNB3 mRNA CTD PMID:18579281 NCBI chr15:98,526,317...98,542,410
Ensembl chr15:98,528,721...98,542,410
JBrowse link
G Camk1d calcium/calmodulin-dependent protein kinase ID increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of CAMK1D mRNA CTD PMID:18579281 NCBI chr 2:5,298,268...5,719,665
Ensembl chr 2:5,298,268...5,719,326
JBrowse link
G Capn6 calpain 6 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of CAPN6 mRNA CTD PMID:18579281 NCBI chr  X:142,585,232...142,610,408
Ensembl chr  X:142,585,227...142,610,410
JBrowse link
G Cdh1 cadherin 1 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of CDH1 mRNA CTD PMID:18579281 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
JBrowse link
G Cirbp cold inducible RNA binding protein increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of CIRBP mRNA CTD PMID:18579281 NCBI chr10:80,001,824...80,008,620
Ensembl chr10:80,001,819...80,008,620
JBrowse link
G Ckm creatine kinase, muscle increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of CKM mRNA CTD PMID:18579281 NCBI chr 7:19,145,019...19,155,508
Ensembl chr 7:19,138,701...19,156,766
JBrowse link
G Clca4a chloride channel accessory 4A decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of CLCA4A mRNA CTD PMID:18579281 NCBI chr 3:144,658,247...144,680,806
Ensembl chr 3:144,658,241...144,680,806
JBrowse link
G Col15a1 collagen, type XV, alpha 1 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of COL15A1 mRNA CTD PMID:18579281 NCBI chr 4:47,207,744...47,313,165
Ensembl chr 4:47,208,161...47,313,167
JBrowse link
G Cyp7b1 cytochrome P450, family 7, subfamily b, polypeptide 1 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of CYP7B1 mRNA CTD PMID:18579281 NCBI chr 3:18,126,108...18,298,054
Ensembl chr 3:18,126,114...18,297,502
JBrowse link
G Ddc dopa decarboxylase increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of DDC mRNA CTD PMID:18579281 NCBI chr11:11,764,101...11,848,144
Ensembl chr11:11,764,101...11,848,144
JBrowse link
G Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of EEPD1 mRNA CTD PMID:18579281 NCBI chr 9:25,392,809...25,515,406
Ensembl chr 9:25,392,843...25,515,406
JBrowse link
G Ephx1 epoxide hydrolase 1, microsomal increases activity EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased activity of EPHX1 protein CTD PMID:3032197 NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469
JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic multiple interactions EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of and results in increased activity of EPHX2 protein CTD PMID:3032197 NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949
JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions ISO 2,4,5-Trichlorophenoxyacetic Acid binds to and results in decreased activity of ESR1 protein CTD PMID:16626760 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
JBrowse link
G Far1 fatty acyl CoA reductase 1 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of FAR1 mRNA CTD PMID:18579281 NCBI chr 7:113,113,008...113,170,713
Ensembl chr 7:113,113,041...113,170,718
JBrowse link
G Fkbp5 FK506 binding protein 5 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of FKBP5 mRNA CTD PMID:18579281 NCBI chr17:28,617,727...28,705,123
Ensembl chr17:28,618,068...28,736,501
JBrowse link
G Fmo2 flavin containing monooxygenase 2 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of FMO2 mRNA CTD PMID:18579281 NCBI chr 1:162,701,886...162,726,327
Ensembl chr 1:162,701,886...162,726,295
JBrowse link
G G0s2 G0/G1 switch gene 2 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of G0S2 mRNA CTD PMID:18579281 NCBI chr 1:192,954,468...192,955,496
Ensembl chr 1:192,954,469...192,955,525
JBrowse link
G Gbf1 golgi-specific brefeldin A-resistance factor 1 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of GBF1 mRNA CTD PMID:18579281 NCBI chr19:46,140,948...46,274,949
Ensembl chr19:46,140,948...46,274,949
JBrowse link
G Gbp9 guanylate-binding protein 9 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of GBP9 mRNA CTD PMID:18579281 NCBI chr 5:105,224,331...105,258,255
Ensembl chr 5:105,225,496...105,287,405
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO
EXP
2,4,5-Trichlorophenoxyacetic Acid results in increased expression of GCLC mRNA
2,4,5-Trichlorophenoxyacetic Acid results in increased expression of GCLC; 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of GCLC mRNA
CTD PMID:10377250 PMID:16426233 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
JBrowse link
G Gde1 glycerophosphodiester phosphodiesterase 1 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of GDE1 mRNA CTD PMID:18579281 NCBI chr 7:118,287,781...118,304,961
Ensembl chr 7:118,287,768...118,305,001
JBrowse link
G Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of GFRA1 mRNA CTD PMID:18579281 NCBI chr19:58,224,013...58,444,387
Ensembl chr19:58,224,036...58,444,341
JBrowse link
G Git2 GIT ArfGAP 2 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of GIT2 mRNA CTD PMID:18579281 NCBI chr 5:114,865,469...114,912,647
Ensembl chr 5:114,865,468...114,913,578
JBrowse link
G Gmppb GDP-mannose pyrophosphorylase B increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of GMPPB mRNA CTD PMID:18579281 NCBI chr 9:107,926,490...107,929,119
Ensembl chr 9:107,926,441...107,930,000
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1, soluble decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of GOT1 mRNA CTD PMID:18579281 NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044
JBrowse link
G Gpm6a glycoprotein m6a decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of GPM6A mRNA CTD PMID:18579281 NCBI chr 8:55,232,469...55,513,913
Ensembl chr 8:55,407,878...55,513,906
JBrowse link
G Gpr12 G-protein coupled receptor 12 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of GPR12 mRNA CTD PMID:18579281 NCBI chr 5:146,518,960...146,523,274
Ensembl chr 5:146,519,208...146,522,049
JBrowse link
G Gpr85 G protein-coupled receptor 85 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of GPR85 mRNA CTD PMID:18579281 NCBI chr 6:13,834,405...13,839,951
Ensembl chr 6:13,834,457...13,839,941
JBrowse link
G Hapln1 hyaluronan and proteoglycan link protein 1 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of HAPLN1 mRNA CTD PMID:18579281 NCBI chr13:89,688,654...89,759,951
Ensembl chr13:89,687,915...89,759,771
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of HMOX1 mRNA CTD PMID:18579281 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of HSD3B5 mRNA CTD PMID:18579281 NCBI chr 3:98,525,952...98,552,850
Ensembl chr 3:98,525,950...98,537,568
JBrowse link
G Hspa8 heat shock protein 8 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of HSPA8 mRNA CTD PMID:18579281 NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383
JBrowse link
G Hspb1 heat shock protein 1 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of HSPB1 mRNA CTD PMID:18579281 NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417
JBrowse link
G Hsph1 heat shock 105kDa/110kDa protein 1 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of HSPH1 mRNA CTD PMID:18579281 NCBI chr 5:149,540,308...149,562,594
Ensembl chr 5:149,537,752...149,559,841
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of IDO2 mRNA CTD PMID:18579281 NCBI chr 8:25,021,908...25,066,430
Ensembl chr 8:25,021,908...25,066,349
JBrowse link
G Ifi47 interferon gamma inducible protein 47 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of IFI47 mRNA CTD PMID:18579281 NCBI chr11:48,967,414...48,987,814
Ensembl chr11:48,967,414...48,987,801
JBrowse link
G Ihh Indian hedgehog increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of IHH mRNA CTD PMID:18579281 NCBI chr 1:74,984,474...74,990,831
Ensembl chr 1:74,984,474...74,990,831
JBrowse link
G Ikbke inhibitor of kappaB kinase epsilon increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of IKBKE mRNA CTD PMID:18579281 NCBI chr 1:131,182,337...131,207,339
Ensembl chr 1:131,182,080...131,207,344
JBrowse link
G Il1r1 interleukin 1 receptor, type I decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of IL1R1 mRNA CTD PMID:18579281 NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417
JBrowse link
G Insc INSC spindle orientation adaptor protein increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of INSC mRNA CTD PMID:18579281 NCBI chr 7:114,342,931...114,449,615
Ensembl chr 7:114,342,929...114,449,618
JBrowse link
G Klf5 Kruppel-like transcription factor 5 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of KLF5 mRNA CTD PMID:18579281 NCBI chr14:99,536,127...99,550,848
Ensembl chr14:99,536,127...99,552,472
JBrowse link
G Limch1 LIM and calponin homology domains 1 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of LIMCH1 mRNA CTD PMID:18579281 NCBI chr 5:66,903,232...67,214,502
Ensembl chr 5:66,903,170...67,214,501
JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of LMCD1 mRNA CTD PMID:18579281 NCBI chr 6:112,250,747...112,307,384
Ensembl chr 6:112,250,719...112,307,386
JBrowse link
G Lpar4 lysophosphatidic acid receptor 4 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of LPAR4 mRNA CTD PMID:18579281 NCBI chr  X:105,964,231...105,977,505
Ensembl chr  X:105,964,231...105,977,506
JBrowse link
G Lpin1 lipin 1 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of LPIN1 mRNA CTD PMID:18579281 NCBI chr12:16,585,670...16,697,020
Ensembl chr12:16,585,670...16,696,967
JBrowse link
G Lrtm1 leucine-rich repeats and transmembrane domains 1 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of LRTM1 mRNA CTD PMID:18579281 NCBI chr14:28,740,165...28,755,599
Ensembl chr14:28,740,165...28,755,602
JBrowse link
G Matk megakaryocyte-associated tyrosine kinase increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of MATK mRNA CTD PMID:18579281 NCBI chr10:81,088,769...81,098,819
Ensembl chr10:81,088,769...81,099,199
JBrowse link
G Mpdz multiple PDZ domain crumbs cell polarity complex component increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of MPDZ mRNA CTD PMID:18579281 NCBI chr 4:81,196,736...81,361,112
Ensembl chr 4:81,196,742...81,361,052
JBrowse link
G Mt1 metallothionein 1 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of MT1 mRNA CTD PMID:18579281 NCBI chr 8:94,905,214...94,906,955
Ensembl chr 8:94,905,710...94,906,955
JBrowse link
G Mt4 metallothionein 4 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of MT4 mRNA CTD PMID:18579281 NCBI chr 8:94,863,832...94,865,659
Ensembl chr 8:94,863,825...94,865,659
JBrowse link
G Mvd mevalonate (diphospho) decarboxylase increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of MVD mRNA CTD PMID:18579281 NCBI chr 8:123,160,335...123,170,161
Ensembl chr 8:123,160,340...123,170,161
JBrowse link
G Mybph myosin binding protein H increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of MYBPH mRNA CTD PMID:18579281 NCBI chr 1:134,121,159...134,128,975
Ensembl chr 1:134,121,186...134,128,970
JBrowse link
G Ndrg4 N-myc downstream regulated gene 4 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of NDRG4 mRNA CTD PMID:18579281 NCBI chr 8:96,403,602...96,441,584
Ensembl chr 8:96,403,608...96,441,747
JBrowse link
G Nherf4 NHERF family PDZ scaffold protein 4 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of NHERF4 mRNA CTD PMID:18579281 NCBI chr 9:44,158,609...44,162,761
Ensembl chr 9:44,158,604...44,162,768
JBrowse link
G Nip7 NIP7, nucleolar pre-rRNA processing protein decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of NIP7 mRNA CTD PMID:18579281 NCBI chr 8:107,783,509...107,787,563
Ensembl chr 8:107,783,509...107,787,563
JBrowse link
G Nrg4 neuregulin 4 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of NRG4 mRNA CTD PMID:18579281 NCBI chr 9:55,127,506...55,190,937
Ensembl chr 9:55,127,506...55,234,128
JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of OAS1A mRNA CTD PMID:18579281 NCBI chr 5:121,034,319...121,045,588
Ensembl chr 5:121,034,319...121,045,584
JBrowse link
G Ogn osteoglycin decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of OGN mRNA CTD PMID:18579281 NCBI chr13:49,761,491...49,777,977
Ensembl chr13:49,761,522...49,777,977
JBrowse link
G Or5b99 olfactory receptor family 5 subfamily B member 99 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of OR5B99 mRNA CTD PMID:18579281 NCBI chr19:12,976,352...12,977,284
Ensembl chr19:12,972,378...12,977,781
JBrowse link
G Pfkp phosphofructokinase, platelet decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PFKP mRNA CTD PMID:18579281 NCBI chr13:6,629,910...6,699,096
Ensembl chr13:6,629,804...6,698,813
JBrowse link
G Plin4 perilipin 4 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PLIN4 mRNA CTD PMID:18579281 NCBI chr17:56,407,587...56,416,947
Ensembl chr17:56,407,591...56,416,803
JBrowse link
G Por cytochrome p450 oxidoreductase decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of POR mRNA CTD PMID:18579281 NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180
JBrowse link
G Ppfibp1 PTPRF interacting protein, binding protein 1 (liprin beta 1) decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PPFIBP1 mRNA CTD PMID:18579281 NCBI chr 6:146,788,107...146,933,523
Ensembl chr 6:146,789,985...146,933,523
JBrowse link
G Ppp1r3a protein phosphatase 1, regulatory subunit 3A decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PPP1R3A mRNA CTD PMID:18579281 NCBI chr 6:14,713,821...14,755,273
Ensembl chr 6:14,713,976...14,755,273
JBrowse link
G Ppp1r3g protein phosphatase 1, regulatory subunit 3G decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PPP1R3G mRNA CTD PMID:18579281 NCBI chr13:36,142,816...36,154,371
Ensembl chr13:36,142,822...36,154,371
JBrowse link
G Prok1 prokineticin 1 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of PROK1 mRNA CTD PMID:18579281 NCBI chr 3:107,139,232...107,147,023
Ensembl chr 3:107,140,113...107,147,023
JBrowse link
G Prr9 proline rich 9 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PRR9 mRNA CTD PMID:18579281 NCBI chr 3:92,029,511...92,031,254
Ensembl chr 3:92,029,511...92,031,254
JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4a1 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PTP4A1 mRNA CTD PMID:18579281 NCBI chr 1:30,979,384...30,988,838
Ensembl chr 1:30,979,383...30,988,390
Ensembl chr 1:30,979,383...30,988,390
JBrowse link
G Retreg1 reticulophagy regulator 1 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of RETREG1 mRNA CTD PMID:18579281 NCBI chr15:25,840,795...25,973,782
Ensembl chr15:25,843,266...25,973,773
JBrowse link
G Rprd1a regulation of nuclear pre-mRNA domain containing 1A decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of RPRD1A mRNA CTD PMID:18579281 NCBI chr18:24,618,017...24,663,306
Ensembl chr18:24,618,017...24,663,261
JBrowse link
G Saa1 serum amyloid A 1 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of SAA1 mRNA CTD PMID:18579281 NCBI chr 7:46,389,921...46,392,404
Ensembl chr 7:46,389,921...46,392,404
JBrowse link
G Selenop selenoprotein P decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of SELENOP mRNA CTD PMID:18579281 NCBI chr15:3,300,249...3,309,992
Ensembl chr15:3,298,029...3,309,990
JBrowse link
G Sema3c sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of SEMA3C mRNA CTD PMID:18579281 NCBI chr 5:17,779,814...17,935,266
Ensembl chr 5:17,779,279...17,935,266
JBrowse link
G Sgk2 serum/glucocorticoid regulated kinase 2 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of SGK2 mRNA CTD PMID:18579281 NCBI chr 2:162,829,249...162,856,059
Ensembl chr 2:162,829,250...162,856,047
JBrowse link
G Slc24a2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of SLC24A2 mRNA CTD PMID:18579281 NCBI chr 4:86,901,361...87,148,780
Ensembl chr 4:86,901,361...87,148,714
JBrowse link
G Slc25a32 solute carrier family 25, member 32 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of SLC25A32 mRNA CTD PMID:18579281 NCBI chr15:38,954,625...38,976,213
Ensembl chr15:38,954,626...38,976,111
JBrowse link
G Slc66a1 solute carrier family 66 member 1 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of SLC66A1 mRNA CTD PMID:18579281 NCBI chr 4:139,021,341...139,038,025
Ensembl chr 4:139,021,340...139,038,019
JBrowse link
G Slc6a15 solute carrier family 6 (neurotransmitter transporter), member 15 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of SLC6A15 mRNA CTD PMID:18579281 NCBI chr10:103,203,320...103,255,240
Ensembl chr10:103,203,644...103,255,238
JBrowse link
G Snx7 sorting nexin 7 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of SNX7 mRNA CTD PMID:18579281 NCBI chr 3:117,575,146...117,662,585
Ensembl chr 3:117,575,296...117,662,585
JBrowse link
G Spon2 spondin 2, extracellular matrix protein increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of SPON2 mRNA CTD PMID:18579281 NCBI chr 5:33,370,862...33,375,596
Ensembl chr 5:33,355,528...33,375,799
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of SREBF1 mRNA CTD PMID:18579281 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407
JBrowse link
G Svil supervillin increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of SVIL mRNA CTD PMID:18579281 NCBI chr18:4,920,497...5,119,290
Ensembl chr18:4,920,540...5,119,299
JBrowse link
G Tacc2 transforming, acidic coiled-coil containing protein 2 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of TACC2 mRNA CTD PMID:18579281 NCBI chr 7:130,154,735...130,369,435
Ensembl chr 7:130,179,168...130,366,515
JBrowse link
G Tbc1d8 TBC1 domain family, member 8 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of TBC1D8 mRNA CTD PMID:18579281 NCBI chr 1:39,410,576...39,517,860
Ensembl chr 1:39,410,573...39,517,836
JBrowse link
G Tcea2 transcription elongation factor A (SII), 2 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of TCEA2 mRNA CTD PMID:18579281 NCBI chr 2:181,322,090...181,329,860
Ensembl chr 2:181,322,103...181,329,864
JBrowse link
G Thra thyroid hormone receptor alpha increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of THRA mRNA CTD PMID:18579281 NCBI chr11:98,631,539...98,659,832
Ensembl chr11:98,631,464...98,659,832
JBrowse link
G Thrb thyroid hormone receptor beta affects binding ISO 2,4,5-Trichlorophenoxyacetic Acid binds to THRB protein CTD PMID:27410513 NCBI chr14:4,429,599...4,810,538
Ensembl chr14:4,431,611...4,809,435
JBrowse link
G Tom1l2 target of myb1-like 2 (chicken) decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of TOM1L2 mRNA CTD PMID:18579281 NCBI chr11:60,114,622...60,243,766
Ensembl chr11:60,117,540...60,243,731
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of TRIB3 mRNA CTD PMID:18579281 NCBI chr 2:152,179,345...152,185,980
Ensembl chr 2:152,179,342...152,185,952
JBrowse link
G Tril TLR4 interactor with leucine-rich repeats decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of TRIL mRNA CTD PMID:18579281 NCBI chr 6:53,792,453...53,797,810
Ensembl chr 6:53,792,453...53,797,815
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of TSC22D1 mRNA CTD PMID:18579281 NCBI chr14:76,652,401...76,745,205
Ensembl chr14:76,652,401...76,745,205
JBrowse link
G Ugt2a3 UDP glucuronosyltransferase 2 family, polypeptide A3 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of UGT2A3 mRNA CTD PMID:18579281 NCBI chr 5:87,472,694...87,485,054
Ensembl chr 5:87,472,831...87,485,054
JBrowse link
G Usp2 ubiquitin specific peptidase 2 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of USP2 mRNA CTD PMID:18579281 NCBI chr 9:43,978,318...44,006,924
Ensembl chr 9:43,978,318...44,006,924
JBrowse link
G Vamp1 vesicle-associated membrane protein 1 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of VAMP1 mRNA CTD PMID:18579281 NCBI chr 6:125,192,544...125,199,269
Ensembl chr 6:125,192,514...125,222,927
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 decreases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of VCAM1 mRNA CTD PMID:18579281 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
G Veph1 ventricular zone expressed PH domain-containing 1 increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of VEPH1 mRNA CTD PMID:18579281 NCBI chr 3:65,960,979...66,204,370
Ensembl chr 3:65,960,979...66,204,258
JBrowse link
G Wars2 tryptophanyl tRNA synthetase 2 (mitochondrial) increases expression EXP 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of WARS2 mRNA CTD PMID:18579281 NCBI chr 3:99,047,423...99,128,546
Ensembl chr 3:99,048,384...99,146,502
JBrowse link
(2-nitrophenyl)acetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces1d carboxylesterase 1D increases hydrolysis ISO CES1 protein results in increased hydrolysis of 2-nitrophenylacetic acid CTD PMID:23123248 NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466
JBrowse link
G Ces2h carboxylesterase 2H increases hydrolysis ISO CES2 protein results in increased hydrolysis of 2-nitrophenylacetic acid CTD PMID:23123248 NCBI chr 8:105,727,462...105,747,042
Ensembl chr 8:105,727,485...105,747,810
JBrowse link
(3,4-dihydroxyphenyl)acetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actb actin, beta affects binding
multiple interactions
ISO 3,4-Dihydroxyphenylacetic Acid analog binds to ACTB protein
Catechin inhibits the reaction [3,4-Dihydroxyphenylacetic Acid analog binds to ACTB protein]; epicatechin gallate inhibits the reaction [3,4-Dihydroxyphenylacetic Acid analog binds to ACTB protein]; Quercetin inhibits the reaction [3,4-Dihydroxyphenylacetic Acid analog binds to ACTB protein]
CTD PMID:19743802 NCBI chr 5:142,888,870...142,892,509
Ensembl chr 5:142,888,870...142,892,509
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 increases phosphorylation
multiple interactions
ISO 3,4-Dihydroxyphenylacetic Acid results in increased phosphorylation of AKT1 protein
[3,4-Dihydroxyphenylacetic Acid co-treated with Glucose] results in increased phosphorylation of AKT1 protein
CTD PMID:29981789 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Cartpt CART prepropeptide increases abundance ISO CARTPT protein results in increased abundance of 3,4-Dihydroxyphenylacetic Acid CTD PMID:15659233 NCBI chr13:100,034,991...100,037,191
Ensembl chr13:100,034,997...100,037,599
JBrowse link
G Cat catalase multiple interactions ISO CAT protein inhibits the reaction [N-Methyl-3,4-methylenedioxyamphetamine results in decreased abundance of 3,4-Dihydroxyphenylacetic Acid] CTD PMID:11435997 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Comt catechol-O-methyltransferase increases methylation
multiple interactions
ISO COMT protein results in increased methylation of 3,4-Dihydroxyphenylacetic Acid
[tolcapone results in decreased activity of COMT protein] which results in increased abundance of 3,4-Dihydroxyphenylacetic Acid
CTD PMID:11160877 PMID:11793163 PMID:15190105 PMID:16012872 NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 increases expression ISO 3,4-Dihydroxyphenylacetic Acid results in increased expression of GSTP1 mRNA CTD PMID:19743802 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G Gys1 glycogen synthase 1, muscle decreases phosphorylation
multiple interactions
ISO 3,4-Dihydroxyphenylacetic Acid results in decreased phosphorylation of GYS1 protein
3,4-Dihydroxyphenylacetic Acid inhibits the reaction [Glucose results in increased phosphorylation of GYS1 protein]
CTD PMID:29981789 NCBI chr 7:45,084,263...45,106,041
Ensembl chr 7:45,084,268...45,106,043
JBrowse link
G Insr insulin receptor multiple interactions ISO 3,4-Dihydroxyphenylacetic Acid inhibits the reaction [Glucose results in decreased expression of and results in decreased phosphorylation of INSR protein]; 3,4-Dihydroxyphenylacetic Acid results in increased expression of and results in increased phosphorylation of INSR protein CTD PMID:29981789 NCBI chr 8:3,200,922...3,329,649
Ensembl chr 8:3,172,061...3,329,617
JBrowse link
G Maob monoamine oxidase B multiple interactions ISO [Selegiline results in decreased activity of MAOB protein] which results in decreased abundance of 3,4-Dihydroxyphenylacetic Acid CTD PMID:16012872 NCBI chr  X:16,575,520...16,683,605
Ensembl chr  X:16,575,521...16,683,605
JBrowse link
G Nos1 nitric oxide synthase 1, neuronal multiple interactions EXP NOS1 protein affects the reaction [Methamphetamine results in decreased abundance of 3,4-Dihydroxyphenylacetic Acid] CTD PMID:11085313 NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 increases expression ISO 3,4-Dihydroxyphenylacetic Acid results in increased expression of NQO1 mRNA CTD PMID:19743802 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases abundance EXP NR3C1 protein results in increased abundance of 3,4-Dihydroxyphenylacetic Acid CTD PMID:11226678 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474
JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions ISO [beta-funaltrexamine binds to and results in decreased activity of OPRM1 protein] inhibits the reaction [Morphine results in increased abundance of 3,4-Dihydroxyphenylacetic Acid] CTD PMID:8884884 NCBI chr10:6,708,593...6,988,209
Ensembl chr10:6,708,506...6,988,198
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions EXP [PARP1 protein results in increased susceptibility to 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] which results in increased abundance of 3,4-Dihydroxyphenylacetic Acid CTD PMID:10318960 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Slc22a8 solute carrier family 22 (organic anion transporter), member 8 multiple interactions ISO 3,4-Dihydroxyphenylacetic Acid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:10224140 NCBI chr19:8,568,576...8,589,199
Ensembl chr19:8,568,618...8,589,199
JBrowse link
G Snca synuclein, alpha decreases abundance EXP SNCA protein mutant form results in decreased abundance of 3,4-Dihydroxyphenylacetic Acid CTD PMID:18622040 NCBI chr 6:60,708,557...60,806,839
Ensembl chr 6:60,708,559...60,806,839
JBrowse link
G Tfam transcription factor A, mitochondrial decreases abundance EXP TFAM gene mutant form results in decreased abundance of 3,4-Dihydroxyphenylacetic Acid CTD PMID:28595911 NCBI chr10:71,061,298...71,074,157
Ensembl chr10:71,061,294...71,074,110
JBrowse link
(4-chloro-2-methylphenoxy)acetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcnka chloride channel, voltage-sensitive Ka decreases activity ISO 2-Methyl-4-chlorophenoxyacetic Acid analog results in decreased activity of CLCNKA protein CTD PMID:15167890 NCBI chr 4:141,111,922...141,126,017
Ensembl chr 4:141,111,921...141,126,035
JBrowse link
G Clcnkb chloride channel, voltage-sensitive Kb decreases activity ISO 2-Methyl-4-chlorophenoxyacetic Acid analog results in decreased activity of CLCNKB protein CTD PMID:15167890 NCBI chr 4:141,131,668...141,143,440
Ensembl chr 4:141,131,664...141,143,325
JBrowse link
G Slc1a2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 affects expression ISO 2-Methyl-4-chlorophenoxyacetic Acid affects the expression of SLC1A2 protein CTD PMID:16019039 NCBI chr 2:102,488,584...102,621,129
Ensembl chr 2:102,489,004...102,621,129
JBrowse link
G Tnf tumor necrosis factor increases expression ISO 2-Methyl-4-chlorophenoxyacetic Acid results in increased expression of TNF protein CTD PMID:10883730 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
(4-nitrophenyl)acetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces1d carboxylesterase 1D increases hydrolysis ISO CES1 protein results in increased hydrolysis of 4-nitrophenylacetic acid CTD PMID:11950785 NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466
JBrowse link
G Ces2h carboxylesterase 2H increases hydrolysis ISO CES2 protein results in increased hydrolysis of 4-nitrophenylacetic acid CTD PMID:11950785 NCBI chr 8:105,727,462...105,747,042
Ensembl chr 8:105,727,485...105,747,810
JBrowse link
(S)-atropine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Hyoscyamine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
1-naphthaleneacetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces2c carboxylesterase 2C increases hydrolysis EXP CES2C protein results in increased hydrolysis of 1-naphthaleneacetic acid CTD PMID:22513142 NCBI chr 8:105,573,700...105,581,115
Ensembl chr 8:105,573,700...105,581,115
JBrowse link
G Ifng interferon gamma increases expression EXP 1-naphthaleneacetic acid results in increased expression of IFNG CTD PMID:20728597 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Il2 interleukin 2 increases expression EXP 1-naphthaleneacetic acid results in increased expression of IL2 CTD PMID:20728597 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il2ra interleukin 2 receptor, alpha chain increases expression EXP 1-naphthaleneacetic acid results in increased expression of IL2RA CTD PMID:20728597 NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004
JBrowse link
G Tnf tumor necrosis factor increases expression EXP 1-naphthaleneacetic acid results in increased expression of TNF CTD PMID:20728597 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 increases glucuronidation ISO UGT2B1 protein results in increased glucuronidation of 1-naphthaleneacetic acid CTD PMID:8302279 NCBI chr 5:87,064,498...87,074,362
Ensembl chr 5:87,064,497...87,074,389
JBrowse link
2,4-D term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP-binding cassette, sub-family B member 4 increases expression
multiple interactions
EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of ABCB4 mRNA
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of ABCB4 mRNA
CTD PMID:9210621 PMID:37567420 NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231
JBrowse link
G Acot1 acyl-CoA thioesterase 1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of ACOT1 mRNA CTD PMID:37567420 NCBI chr12:84,056,276...84,064,444
Ensembl chr12:84,056,264...84,065,145
JBrowse link
G Adgrf4 adhesion G protein-coupled receptor F4 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of ADGRF4 mRNA CTD PMID:37567420 NCBI chr17:42,967,099...43,008,460
Ensembl chr17:42,967,782...43,003,175
JBrowse link
G Alb albumin affects binding ISO 2,4-Dichlorophenoxyacetic Acid binds to ALB protein CTD PMID:9877224 PMID:11451446 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of ALDH1L2 mRNA CTD PMID:37567420 NCBI chr10:83,320,386...83,370,008
Ensembl chr10:83,323,314...83,370,004
JBrowse link
G Aldh3b3 aldehyde dehydrogenase 3 family, member B3 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of ALDH3B3 mRNA CTD PMID:37567420 NCBI chr19:4,008,733...4,022,419
Ensembl chr19:4,008,645...4,022,103
JBrowse link
G Alpk3 alpha-kinase 3 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of ALPK3 mRNA CTD PMID:37567420 NCBI chr 7:80,707,321...80,755,360
Ensembl chr 7:80,707,348...80,755,360
JBrowse link
G Aoc1 amine oxidase, copper-containing 1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of AOC1 mRNA CTD PMID:37567420 NCBI chr 6:48,872,189...48,886,122
Ensembl chr 6:48,849,830...48,886,122
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression
multiple interactions
EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of APAF1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of APAF1 protein
[Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of APAF1 mRNA; [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of APAF1 protein
CTD PMID:33865415 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632
JBrowse link
G Apol7e apolipoprotein L 7e multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of APOL7E mRNA CTD PMID:37567420 NCBI chr15:77,579,494...77,603,488
Ensembl chr15:77,583,057...77,603,485
JBrowse link
G Ar androgen receptor multiple interactions ISO
EXP
2,4-Dichlorophenoxyacetic Acid inhibits the reaction [Androgens binds to AR protein]; 2,4-Dichlorophenoxyacetic Acid promotes the reaction [Dihydrotestosterone results in increased localization of and results in increased activity of AR protein]
[2,4-Dichlorophenoxyacetic Acid co-treated with Glyphosate co-treated with lard co-treated with Cholesterol co-treated with Glucose co-treated with Sucrose co-treated with Fructose] results in decreased expression of AR protein; [Sucrose co-treated with Dietary Fats co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of AR mRNA
CTD PMID:16107550 PMID:37516258 PMID:37615203 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821
JBrowse link
G Arhgap33os Rho GTPase activating protein 33, opposite strand multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of ARHGAP33OS mRNA CTD PMID:37567420 NCBI chr 7:30,214,547...30,221,618
Ensembl chr 7:30,214,547...30,221,618
JBrowse link
G Art2b ADP-ribosyltransferase 2b multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of ART2B mRNA CTD PMID:37567420 NCBI chr 7:101,224,936...101,234,790
Ensembl chr 7:101,226,177...101,234,807
JBrowse link
G Aspg asparaginase multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of ASPG mRNA CTD PMID:37567420 NCBI chr12:112,073,117...112,094,007
Ensembl chr12:112,073,113...112,093,993
JBrowse link
G Axin2 axin 2 increases expression
multiple interactions
EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of AXIN2 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of AXIN2 protein
[Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of AXIN2 mRNA
CTD PMID:34463001 NCBI chr11:108,808,687...108,841,609
Ensembl chr11:108,811,175...108,841,609
JBrowse link
G Becn1 beclin 1, autophagy related decreases expression
multiple interactions
ISO
EXP
2,4-Dichlorophenoxyacetic Acid results in decreased expression of BECN1 protein
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased expression of BECN1 protein]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased expression of BECN1 mRNA]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased expression of BECN1 protein]
CTD PMID:34464015 PMID:35099110 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
JBrowse link
G Cacna1s calcium channel, voltage-dependent, L type, alpha 1S subunit multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CACNA1S mRNA CTD PMID:37567420 NCBI chr 1:135,980,549...136,047,268
Ensembl chr 1:135,980,488...136,047,560
JBrowse link
G Casp1 caspase 1 multiple interactions
increases cleavage
decreases cleavage
ISO
EXP
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased cleavage of CASP1 protein]
2,4-Dichlorophenoxyacetic Acid results in decreased cleavage of CASP1 protein
CTD PMID:34464015 PMID:35099110 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
EXP
ISO
2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP3 protein; 2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP3 protein modified form
2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of CASP3 mRNA]; FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP3 protein modified form]; FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP3 protein]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP3 protein modified form]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP3 protein]
[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] promotes the reaction [Ethanol results in increased expression of CASP3 mRNA]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of CASP3 mRNA; Ethanol promotes the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of CASP3 mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP3 protein modified form]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP3 protein]
CTD PMID:36085217 PMID:36214342 PMID:37516258 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp8 caspase 8 increases expression
multiple interactions
EXP
ISO
2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP8 protein; 2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP8 protein modified form
[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] affects the reaction [Ethanol results in increased expression of CASP8 mRNA]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of CASP8 mRNA; Ethanol affects the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of CASP8 mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP8 protein modified form]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP8 protein]
FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP8 protein modified form]; FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP8 protein]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP8 protein modified form]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP8 protein]
CTD PMID:36085217 PMID:36214342 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Casp9 caspase 9 multiple interactions ISO [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] promotes the reaction [Ethanol results in increased expression of CASP9 mRNA]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of CASP9 mRNA; Ethanol promotes the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of CASP9 mRNA] CTD PMID:36085217 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Cat catalase multiple interactions ISO
EXP
[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] promotes the reaction [Ethanol results in decreased activity of CAT protein]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in decreased activity of CAT protein; Ethanol promotes the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in decreased activity of CAT protein]
2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of CAT mRNA]
CTD PMID:36085217 PMID:37516258 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccdc120 coiled-coil domain containing 120 decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of CCDC120 mRNA CTD PMID:15878651 NCBI chr  X:7,597,953...7,607,563
Ensembl chr  X:7,597,953...7,617,144
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of CCL11 protein CTD PMID:19467290 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
multiple interactions
EXP
ISO
2,4-Dichlorophenoxyacetic Acid results in increased expression of CCL2 protein
[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] affects the reaction [Ethanol results in increased expression of CCL2 mRNA]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of CCL2 mRNA; Ethanol promotes the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of CCL2 mRNA]
CTD PMID:19467290 PMID:36085217 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of CCL4 protein CTD PMID:19467290 NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509
JBrowse link
G Cd209f CD209f antigen multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CD209F mRNA CTD PMID:37567420 NCBI chr 8:4,152,784...4,155,838
Ensembl chr 8:4,152,787...4,155,835
JBrowse link
G Cd40lg CD40 ligand multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CD40LG mRNA CTD PMID:37567420 NCBI chr  X:56,257,448...56,269,402
Ensembl chr  X:56,257,503...56,269,402
JBrowse link
G Cd5 CD5 antigen multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CD5 mRNA CTD PMID:37567420 NCBI chr19:10,695,471...10,716,390
Ensembl chr19:10,694,480...10,716,366
JBrowse link
G Cdk6 cyclin dependent kinase 6 increases expression
multiple interactions
EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of CDK6 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of CDK6 protein
[Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CDK6 mRNA; [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CDK6 protein
CTD PMID:33865415 NCBI chr 5:3,391,004...3,581,008
Ensembl chr 5:3,391,485...3,581,008
JBrowse link
G Ceacam13 CEA cell adhesion molecule 13 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CEACAM3 mRNA CTD PMID:37567420 NCBI chr 7:17,743,814...17,753,145
Ensembl chr 7:17,743,814...17,753,146
JBrowse link
G Celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of CELSR3 mRNA CTD PMID:37567420 NCBI chr 9:108,703,244...108,730,168
Ensembl chr 9:108,703,519...108,730,168
JBrowse link
G Ces1g carboxylesterase 1G multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CES1G mRNA CTD PMID:37567420 NCBI chr 8:94,028,997...94,063,837
Ensembl chr 8:94,028,997...94,063,936
JBrowse link
G Cimap1c ciliary microtubule associated protein 1C multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of CIMAP1C mRNA CTD PMID:37567420 NCBI chr 9:56,755,940...56,779,199
Ensembl chr 9:56,755,943...56,771,963
JBrowse link
G Cldn1 claudin 1 decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of CLDN1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of CLDN1 protein CTD PMID:28699141 NCBI chr16:26,175,395...26,190,589
Ensembl chr16:26,175,392...26,190,591
JBrowse link
G Clk1 CDC-like kinase 1 decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of CLK1 mRNA CTD PMID:15878651 NCBI chr 1:58,451,147...58,463,247
Ensembl chr 1:58,449,348...58,463,225
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of CNP protein CTD PMID:18460445 NCBI chr11:100,465,765...100,472,565
Ensembl chr11:100,465,730...100,482,555
JBrowse link
G Cntnap2 contactin associated protein-like 2 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CNTNAP2 mRNA CTD PMID:37567420 NCBI chr 6:45,036,995...47,278,330
Ensembl chr 6:45,036,291...47,281,147
JBrowse link
G Col6a5 collagen, type VI, alpha 5 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of COL6A5 mRNA CTD PMID:37567420 NCBI chr 9:105,733,269...105,839,743
Ensembl chr 9:105,733,277...105,837,842
JBrowse link
G Col6a6 collagen, type VI, alpha 6 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of COL6A6 mRNA CTD PMID:37567420 NCBI chr 9:105,566,616...105,705,413
Ensembl chr 9:105,565,008...105,705,359
JBrowse link
G Crat carnitine acetyltransferase increases activity EXP 2,4-Dichlorophenoxyacetic Acid results in increased activity of CRAT protein CTD PMID:1755024 NCBI chr 2:30,290,483...30,305,602
Ensembl chr 2:30,290,483...30,305,825
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases expression
ISO PPARB protein affects the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CREB1 mRNA]
2,4-Dichlorophenoxyacetic Acid results in increased expression of CREB1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of CREB1 protein
CTD PMID:29633193 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CREB3L3 mRNA CTD PMID:37567420 NCBI chr10:80,920,163...80,934,706
Ensembl chr10:80,920,158...80,934,708
JBrowse link
G Cst6 cystatin E/M multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of CST6 mRNA CTD PMID:37567420 NCBI chr19:5,394,733...5,399,602
Ensembl chr19:5,394,733...5,399,602
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions ISO [Glyphosate co-treated with 2,4-Dichlorophenoxyacetic Acid co-treated with mancozeb co-treated with Atrazine] results in increased expression of CXCL8 protein CTD PMID:37236337 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 affects expression EXP 2,4-Dichlorophenoxyacetic Acid affects the expression of CYP17A1 mRNA CTD PMID:26838045 NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of CYP1A1 mRNA CTD PMID:10910964 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of CYP1A2 mRNA CTD PMID:10910964 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of CYP1B1 mRNA CTD PMID:10910964 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CYP26B1 mRNA CTD PMID:37567420 NCBI chr 6:84,548,396...84,570,890
Ensembl chr 6:84,548,396...84,570,890
JBrowse link
G Cyp2d10 cytochrome P450, family 2, subfamily d, polypeptide 10 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of CYP2D10 mRNA CTD PMID:37567420 NCBI chr15:82,287,046...82,291,449
Ensembl chr15:82,287,047...82,291,396
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] promotes the reaction [Ethanol results in increased expression of CYP2E1 mRNA]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of CYP2E1 mRNA; Ethanol promotes the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of CYP2E1 mRNA] CTD PMID:36085217 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Cyp2j15-ps cytochrome P450, family 2, subfamily j, member 15, pseudogene multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of CYP2J15-PS mRNA CTD PMID:37567420 NCBI chr 4:96,133,797...96,162,508
Ensembl chr 4:96,133,797...96,162,507
JBrowse link
G Cyp4a14 cytochrome P450, family 4, subfamily a, polypeptide 14 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CYP4A14 mRNA CTD PMID:37567420 NCBI chr 4:115,343,397...115,353,355
Ensembl chr 4:115,343,397...115,353,339
JBrowse link
G D5Ertd605e DNA segment, Chr 5, ERATO Doi 605, expressed multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of D5ERTD605E mRNA CTD PMID:37567420 NCBI chr 5:147,355,430...147,359,854
Ensembl chr 5:147,355,399...147,359,860
JBrowse link
G Dbh dopamine beta hydroxylase decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of DBH protein CTD PMID:16931444 NCBI chr 2:27,055,519...27,073,216
Ensembl chr 2:27,055,245...27,073,212
JBrowse link
G Dbp D site albumin promoter binding protein multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of DBP mRNA CTD PMID:37567420 NCBI chr 7:45,354,658...45,359,579
Ensembl chr 7:45,354,512...45,359,627
JBrowse link
G Dclre1c DNA cross-link repair 1C increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of DCLRE1C mRNA CTD PMID:15878651 NCBI chr 2:3,425,112...3,475,248
Ensembl chr 2:3,425,168...3,465,167
JBrowse link
G Ddb2 damage specific DNA binding protein 2 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of DDB2 mRNA CTD PMID:15878651 NCBI chr 2:91,041,924...91,067,465
Ensembl chr 2:91,041,917...91,067,327
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of DDIT3 mRNA CTD PMID:34626751 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Dicer1 dicer 1, ribonuclease type III multiple interactions EXP 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of DICER1 mRNA] CTD PMID:37516258 NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions EXP 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of DNMT1 mRNA] CTD PMID:37516258 NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184
JBrowse link
G Dok7 docking protein 7 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of DOK7 mRNA CTD PMID:37567420 NCBI chr 5:35,213,922...35,245,183
Ensembl chr 5:35,214,110...35,245,183
JBrowse link
G Drosha drosha, ribonuclease type III multiple interactions EXP 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of DROSHA mRNA] CTD PMID:37516258 NCBI chr15:12,824,893...12,935,377
Ensembl chr15:12,824,901...12,935,377
JBrowse link
G Dusp5 dual specificity phosphatase 5 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of DUSP5 mRNA CTD PMID:37567420 NCBI chr19:53,517,576...53,530,240
Ensembl chr19:53,517,540...53,530,862
JBrowse link
G Ephx1 epoxide hydrolase 1, microsomal increases activity EXP 2,4-Dichlorophenoxyacetic Acid results in increased activity of EPHX1 protein CTD PMID:3032197 NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469
JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic increases activity EXP 2,4-Dichlorophenoxyacetic Acid results in increased activity of EPHX2 protein CTD PMID:1755024 PMID:3032197 NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949
JBrowse link
G Fadd Fas associated via death domain increases expression
multiple interactions
ISO
EXP
2,4-Dichlorophenoxyacetic Acid results in increased expression of FADD protein
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FADD protein]
FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FADD protein]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FADD protein]
CTD PMID:36214342 NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200
JBrowse link
G Fam163a family with sequence similarity 163, member A multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of FAM163A mRNA CTD PMID:37567420 NCBI chr 1:155,951,702...156,033,027
Ensembl chr 1:155,951,712...156,032,596
JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases expression
increases response to substance
ISO
EXP
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FAS protein]
FAS protein results in increased susceptibility to 2,4-Dichlorophenoxyacetic Acid
FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased secretion of INHBB protein]; FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP3 protein modified form]; FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP3 protein]; FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP8 protein modified form]; FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP8 protein]; FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FADD protein]; FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FASL protein]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FAS protein]
CTD PMID:36214342 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fasl Fas ligand multiple interactions
increases expression
EXP
ISO
FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FASL protein]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FASL protein]
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FASLG protein]
CTD PMID:36214342 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Fbxo48 F-box protein 48 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of FBXO48 mRNA CTD PMID:37567420 NCBI chr11:16,901,225...16,908,516
Ensembl chr11:16,901,375...16,904,772
JBrowse link
G Fendrr Foxf1 adjacent non-coding developmental regulatory RNA multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of FENDRR mRNA CTD PMID:37567420 NCBI chr 8:121,781,621...121,809,849
Ensembl chr 8:121,781,621...121,809,849
JBrowse link
G Ffar3 free fatty acid receptor 3 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of FFAR3 mRNA CTD PMID:37567420 NCBI chr 7:30,553,755...30,555,603
Ensembl chr 7:30,553,755...30,555,603
JBrowse link
G Fhad1 forkhead-associated phosphopeptide binding domain 1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of FHAD1 mRNA CTD PMID:37567420 NCBI chr 4:141,617,741...141,742,438
Ensembl chr 4:141,617,749...141,742,393
JBrowse link
G Flg filaggrin multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of FLG mRNA CTD PMID:37567420 NCBI chr 3:93,180,853...93,200,996
Ensembl chr 3:93,180,830...93,200,993
JBrowse link
G Foxo1 forkhead box O1 increases expression
multiple interactions
ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of FOXO1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of FOXO1 protein
PPARB protein affects the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FOXO1 mRNA]
CTD PMID:29633193 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
JBrowse link
G Fth1 ferritin heavy polypeptide 1 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of FTH1 mRNA CTD PMID:15878651 NCBI chr19:9,957,964...9,962,475
Ensembl chr19:9,957,962...9,962,462
JBrowse link
G Ftl1 ferritin light polypeptide 1 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of FTL mRNA CTD PMID:15878651 NCBI chr 7:45,107,368...45,109,310
Ensembl chr 7:45,107,368...45,109,308
JBrowse link
G Galnt16 polypeptide N-acetylgalactosaminyltransferase 16 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of GALNT16 mRNA CTD PMID:37567420 NCBI chr12:80,565,245...80,650,672
Ensembl chr12:80,565,051...80,677,746
JBrowse link
G Galnt2 polypeptide N-acetylgalactosaminyltransferase 2 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of GALNT2 mRNA CTD PMID:37567420 NCBI chr 8:124,958,133...125,072,461
Ensembl chr 8:124,958,130...125,072,463
JBrowse link
G Gcsam germinal center associated, signaling and motility multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of GCSAM mRNA CTD PMID:37567420 NCBI chr16:45,430,803...45,443,230
Ensembl chr16:45,430,743...45,443,230
JBrowse link
G Gfap glial fibrillary acidic protein increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of GFAP mRNA CTD PMID:22954530 NCBI chr11:102,778,162...102,791,368
Ensembl chr11:102,778,162...102,791,738
JBrowse link
G Gli2 GLI-Kruppel family member GLI2 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of GLI2 mRNA CTD PMID:37567420 NCBI chr 1:118,761,791...118,987,578
Ensembl chr 1:118,761,862...118,981,349
JBrowse link
G Gna15 guanine nucleotide binding protein, alpha 15 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of GNA15 mRNA CTD PMID:37567420 NCBI chr10:81,338,147...81,360,283
Ensembl chr10:81,338,140...81,360,059
JBrowse link
G Golt1a golgi transport 1A multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of GOLT1A mRNA CTD PMID:37567420 NCBI chr 1:133,237,561...133,250,764
Ensembl chr 1:133,237,538...133,250,764
Ensembl chr 1:133,237,538...133,250,764
JBrowse link
G Gp5 glycoprotein 5 platelet multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of GP5 mRNA CTD PMID:37567420 NCBI chr16:30,126,503...30,129,599
Ensembl chr16:30,126,503...30,129,597
JBrowse link
G Gp6 glycoprotein 6 platelet multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of GP6 mRNA CTD PMID:37567420 NCBI chr 7:4,365,852...4,400,849
Ensembl chr 7:4,366,964...4,400,743
JBrowse link
G Gpr151 G protein-coupled receptor 151 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of GPR151 mRNA CTD PMID:37567420 NCBI chr18:42,710,946...42,712,717
Ensembl chr18:42,710,946...42,712,717
JBrowse link
G Gpr171 G protein-coupled receptor 171 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of GPR171 mRNA CTD PMID:37567420 NCBI chr 3:59,003,869...59,009,242
Ensembl chr 3:59,003,869...59,009,242
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions ISO [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] promotes the reaction [Ethanol results in increased expression of GPT protein]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of GPT protein; Ethanol promotes the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of GPT protein] CTD PMID:36085217 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases activity EXP 2,4-Dichlorophenoxyacetic Acid results in decreased activity of GPX1 protein CTD PMID:35099110 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Gsr glutathione reductase multiple interactions EXP 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of GSR mRNA] CTD PMID:37516258 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
JBrowse link
G Gssos1 glutathione synthase, opposite strand 1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of GSSOS1 mRNA CTD PMID:37567420 Ensembl chr 2:155,434,239...155,436,875 JBrowse link
G Gucy2e guanylate cyclase 2e multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of GUCY2E mRNA CTD PMID:37567420 NCBI chr11:69,108,943...69,128,083
Ensembl chr11:69,108,943...69,127,862
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of HAMP mRNA CTD PMID:37567420 NCBI chr 7:30,641,793...30,643,454
Ensembl chr 7:30,641,793...30,643,457
JBrowse link
G Hapln1 hyaluronan and proteoglycan link protein 1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of HAPLN1 mRNA CTD PMID:37567420 NCBI chr13:89,688,654...89,759,951
Ensembl chr13:89,687,915...89,759,771
JBrowse link
G Hcrt hypocretin multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of HCRT mRNA CTD PMID:37567420 NCBI chr11:100,652,519...100,653,757
Ensembl chr11:100,651,895...100,653,757
JBrowse link
G Hhipl1 hedgehog interacting protein-like 1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of HHIPL1 mRNA CTD PMID:37567420 NCBI chr12:108,272,100...108,294,559
Ensembl chr12:108,272,529...108,297,128
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of HMGCR CTD PMID:26838045 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of HMGCS1 CTD PMID:26838045 NCBI chr13:120,151,887...120,169,796
Ensembl chr13:120,151,915...120,169,796
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of HMOX1 mRNA CTD PMID:37567420 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hsf2bp heat shock transcription factor 2 binding protein multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of HSF2BP mRNA CTD PMID:37567420 NCBI chr17:32,163,743...32,253,869
Ensembl chr17:32,163,743...32,255,323
JBrowse link
G Ifng interferon gamma increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of IFNG CTD PMID:20728597 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Igfn1 immunoglobulin-like and fibronectin type III domain containing 1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of IGFN1 mRNA CTD PMID:37567420 NCBI chr 1:135,880,943...135,968,663
Ensembl chr 1:135,881,316...135,934,080
JBrowse link
G Ighv1-58 immunoglobulin heavy variable 1-58 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of IGHV1-58 mRNA CTD PMID:37567420 NCBI chr12:115,275,786...115,276,217
Ensembl chr12:115,275,786...115,276,219
JBrowse link
G Ighv1-80 immunoglobulin heavy variable 1-80 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of IGHV1-80 mRNA CTD PMID:37567420 NCBI chr12:115,875,964...115,876,257
Ensembl chr12:115,875,964...115,876,396
JBrowse link
G Ighv10-1 immunoglobulin heavy variable 10-1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of IGHV10-1 mRNA CTD PMID:37567420 NCBI chr12:114,442,627...114,443,071
Ensembl chr12:114,442,625...114,443,071
JBrowse link
G Ighv5-9-1 immunoglobulin heavy variable 5-9-1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of IGHV5-9-1 mRNA CTD PMID:37567420 NCBI chr12:113,699,733...113,700,026
Ensembl chr12:113,699,731...113,700,250
JBrowse link
G Ighv7-1 immunoglobulin heavy variable 7-1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of IGHV7-1 mRNA CTD PMID:37567420 NCBI chr12:113,860,028...113,860,566
Ensembl chr12:113,860,028...113,860,566
JBrowse link
G Igkv1-133 immunoglobulin kappa variable 1-133 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of IGKV1-133 mRNA CTD PMID:37567420 NCBI chr 6:67,701,898...67,702,645
Ensembl chr 6:67,701,886...67,702,645
JBrowse link
G Igkv1-88 immunoglobulin kappa chain variable 1-88 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of IGKV1-88 mRNA CTD PMID:37567420 NCBI chr 6:68,839,249...68,840,015
Ensembl chr 6:68,839,249...68,840,015
JBrowse link
G Igkv15-103 immunoglobulin kappa chain variable 15-103 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of IGKV15-103 mRNA CTD PMID:37567420 NCBI chr 6:68,414,452...68,414,909
Ensembl chr 6:68,414,424...68,414,909
JBrowse link
G Igkv4-86 immunoglobulin kappa variable 4-86 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of IGKV4-86 mRNA CTD PMID:37567420 NCBI chr 6:68,887,395...68,887,922
Ensembl chr 6:68,887,395...68,887,957
JBrowse link
G Igkv5-45 immunoglobulin kappa chain variable 5-45 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of IGKV5-45 mRNA CTD PMID:37567420 NCBI chr 6:69,752,734...69,753,290
Ensembl chr 6:69,752,734...69,753,328
JBrowse link
G Igkv6-32 immunoglobulin kappa variable 6-32 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of IGKV6-32 mRNA CTD PMID:37567420 NCBI chr 6:70,051,008...70,051,568
Ensembl chr 6:70,051,008...70,051,587
JBrowse link
G Igkv8-24 immunoglobulin kappa chain variable 8-24 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of IGKV8-24 mRNA CTD PMID:37567420 NCBI chr 6:70,193,842...70,194,405
Ensembl chr 6:70,193,842...70,194,405
JBrowse link
G Iigp1 interferon inducible GTPase 1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of IIGP1 mRNA CTD PMID:37567420 NCBI chr18:60,506,688...60,525,706
Ensembl chr18:60,509,099...60,525,706
JBrowse link
G Il10 interleukin 10 multiple interactions EXP 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of IL10 mRNA] CTD PMID:37516258 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il12b interleukin 12b multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of IL12B mRNA CTD PMID:37567420 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860
JBrowse link
G Il18 interleukin 18 multiple interactions
increases expression
ISO
EXP
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL18 mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL18 protein]
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL18 mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL18 protein]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL18 mRNA]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL18 protein]
2,4-Dichlorophenoxyacetic Acid results in increased expression of IL18 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of IL18 protein
CTD PMID:34464015 PMID:35099110 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
ISO
EXP
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL1B mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL1B protein]
[aminomethylphosphonic acid (AMPA) co-treated with 2,4-Dichlorophenoxyacetic Acid metabolite co-treated with Ethylenethiourea co-treated with desethylatrazine] results in decreased expression of IL1B protein
2,4-Dichlorophenoxyacetic Acid results in increased expression of IL1B mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of IL1B protein
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL1B mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL1B protein]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL1B mRNA]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL1B protein]
CTD PMID:34464015 PMID:35099110 PMID:37236337 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of IL1RL1 mRNA CTD PMID:15878651 NCBI chr 1:40,444,105...40,504,575
Ensembl chr 1:40,468,730...40,504,575
JBrowse link
G Il2 interleukin 2 increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of IL2 CTD PMID:20728597 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il2ra interleukin 2 receptor, alpha chain increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of IL2RA CTD PMID:20728597 NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004
JBrowse link
G Il4 interleukin 4 increases expression
increases secretion
EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of IL4 protein
2,4-Dichlorophenoxyacetic Acid results in increased secretion of IL4 protein
CTD PMID:19467290 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il5 interleukin 5 increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of IL5 protein CTD PMID:19467290 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
EXP
ISO
2,4-Dichlorophenoxyacetic Acid results in increased expression of IL6 protein
2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of IL6 mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL6 protein]
CTD PMID:19467290 PMID:34464015 PMID:35099110 PMID:37516258 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Inhbb inhibin beta-B decreases secretion
multiple interactions
EXP 2,4-Dichlorophenoxyacetic Acid results in decreased secretion of INHBB protein
FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased secretion of INHBB protein]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased secretion of INHBB protein]
CTD PMID:36214342 NCBI chr 1:119,343,193...119,349,978
Ensembl chr 1:119,343,195...119,349,978
JBrowse link
G Islr2 immunoglobulin superfamily containing leucine-rich repeat 2 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of ISLR2 mRNA CTD PMID:37567420 NCBI chr 9:58,103,580...58,113,563
Ensembl chr 9:58,103,580...58,111,602
JBrowse link
G Ism2 isthmin 2 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of ISM2 mRNA CTD PMID:37567420 NCBI chr12:87,325,412...87,346,624
Ensembl chr12:87,325,412...87,346,479
JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) increases expression
multiple interactions
EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of ITGB1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of ITGB1 protein
[Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of ITGB1 mRNA; [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of ITGB1 protein
CTD PMID:33865415 NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681
JBrowse link
G Kcnip2 Kv channel-interacting protein 2 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of KCNIP2 mRNA CTD PMID:37567420 NCBI chr19:45,780,785...45,804,948
Ensembl chr19:45,780,278...45,804,500
JBrowse link
G Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of KCNMA1 mRNA CTD PMID:37567420 NCBI chr14:23,342,356...24,055,173
Ensembl chr14:23,339,499...24,064,559
JBrowse link
G Krt20 keratin 20 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of KRT20 mRNA CTD PMID:37567420 NCBI chr11:99,319,211...99,328,979
Ensembl chr11:99,319,229...99,328,976
JBrowse link
G Lax1 lymphocyte transmembrane adaptor 1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of LAX1 mRNA CTD PMID:37567420 NCBI chr 1:133,606,767...133,620,760
Ensembl chr 1:133,606,829...133,617,846
JBrowse link
G Lca5l Leber congenital amaurosis 5-like multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of LCA5L mRNA CTD PMID:37567420 NCBI chr16:95,959,605...95,993,450
Ensembl chr16:95,959,607...95,993,471
JBrowse link
G Ldha lactate dehydrogenase A decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of LDHA mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of LDHA protein CTD PMID:23538319 NCBI chr 7:46,491,698...46,505,051
Ensembl chr 7:46,490,899...46,505,051
JBrowse link
G Lin7b lin-7 homolog B, crumbs cell polarity complex component multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of LIN7B mRNA CTD PMID:37567420 NCBI chr 7:45,017,315...45,019,988
Ensembl chr 7:45,017,315...45,020,007
JBrowse link
G Llcfc1 LLLL and CFNLAS motif containing 1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of LLCFC1 mRNA CTD PMID:37567420 NCBI chr 6:41,661,321...41,662,651
Ensembl chr 6:41,661,365...41,662,651
JBrowse link
G Lrch4 leucine-rich repeats and calponin homology (CH) domain containing 4 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of LRCH4 mRNA CTD PMID:37567420 NCBI chr 5:137,627,385...137,639,361
Ensembl chr 5:137,627,383...137,639,361
JBrowse link
G Lrrtm1 leucine rich repeat transmembrane neuronal 1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of LRRTM1 mRNA CTD PMID:37567420 NCBI chr 6:77,192,762...77,236,898
Ensembl chr 6:77,219,672...77,234,774
JBrowse link
G Maob monoamine oxidase B multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of MAOB mRNA CTD PMID:37567420 NCBI chr  X:16,575,520...16,683,605
Ensembl chr  X:16,575,521...16,683,605
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
affects localization
decreases expression
ISO
EXP
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased expression of MAP1LC3B mRNA]
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid affects the localization of MAP1LC3B protein]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased expression of MAP1LC3B mRNA]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased expression of MAP1LC3B mRNA]
CTD PMID:34464015 PMID:35099110 NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499
JBrowse link
G Mbp myelin basic protein decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of MBP protein CTD PMID:18460445 NCBI chr18:82,492,883...82,603,762
Ensembl chr18:82,493,271...82,603,762
JBrowse link
G Mir6407 microRNA 6407 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of MIR6407 mRNA CTD PMID:37567420 NCBI chr19:52,999,087...52,999,187
Ensembl chr19:52,999,087...52,999,187
JBrowse link
G Mir7085 microRNA 7085 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of MIR7085 mRNA CTD PMID:37567420 NCBI chr 9:44,311,720...44,311,785
Ensembl chr 9:44,311,720...44,311,785
JBrowse link
G Mir7659 microRNA 7659 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of MIR7659 mRNA CTD PMID:37567420 NCBI chr10:78,175,984...78,176,041
Ensembl chr10:78,175,984...78,176,041
JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 multiple interactions EXP 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of MKI67 mRNA] CTD PMID:37516258 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of MTHFD2 mRNA CTD PMID:37567420 NCBI chr 6:83,282,686...83,302,926
Ensembl chr 6:83,282,673...83,302,890
JBrowse link
G Myc myelocytomatosis oncogene decreases methylation EXP 2,4-Dichlorophenoxyacetic Acid results in decreased methylation of MYC promoter CTD PMID:11857776 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
JBrowse link
G Nanp N-acetylneuraminic acid phosphatase multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of NANP mRNA CTD PMID:37567420 NCBI chr 2:150,871,605...150,881,299
Ensembl chr 2:150,871,605...150,881,318
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions
increases expression
EXP [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of NFKB1 mRNA; [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of NFKB1 protein
2,4-Dichlorophenoxyacetic Acid results in increased expression of NFKB1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of NFKB1 protein
CTD PMID:33865415 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions
increases expression
ISO
EXP
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of NLRP3 mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of NLRP3 protein]
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of NLRP3 protein]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased expression of BECN1 mRNA]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased expression of BECN1 protein]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased expression of MAP1LC3B mRNA]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL18 mRNA]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL18 protein]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL1B mRNA]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL1B protein]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of SQSTM1 mRNA]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of SQSTM1 protein]
2,4-Dichlorophenoxyacetic Acid results in increased expression of NLRP3 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of NLRP3 protein
CTD PMID:34464015 PMID:35099110 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
JBrowse link
G Nobox NOBOX oogenesis homeobox multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of NOBOX mRNA CTD PMID:37567420 NCBI chr 6:43,280,608...43,287,006
Ensembl chr 6:43,280,608...43,286,488
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO
EXP
2,4-Dichlorophenoxyacetic Acid binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186
JBrowse link
G Nrg1 neuregulin 1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of NRG1 mRNA CTD PMID:37567420 NCBI chr 8:32,299,493...33,381,858
Ensembl chr 8:32,304,579...33,374,825
Ensembl chr 8:32,304,579...33,374,825
JBrowse link
G Nt5c1a 5'-nucleotidase, cytosolic IA multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of NT5C1A mRNA CTD PMID:37567420 NCBI chr 4:123,095,026...123,119,128
Ensembl chr 4:123,095,297...123,110,068
JBrowse link
G Ntm neurotrimin multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of NTM mRNA CTD PMID:37567420 NCBI chr 9:28,906,045...29,874,565
Ensembl chr 9:28,906,046...29,874,437
JBrowse link
G Nxph4 neurexophilin 4 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of NXPH4 mRNA CTD PMID:37567420 NCBI chr10:127,361,342...127,370,428
Ensembl chr10:127,361,342...127,370,428
JBrowse link
G Ocln occludin decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of OCLN mRNA CTD PMID:28699141 NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
JBrowse link
G Or2y1f olfactory receptor family 2 subfamily Y member 1F multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of OR2Y1F mRNA CTD PMID:37567420 NCBI chr11:49,184,124...49,185,149
Ensembl chr11:49,176,109...49,186,718
JBrowse link
G Oxt oxytocin decreases secretion ISO 2,4-Dichlorophenoxyacetic Acid results in decreased secretion of OXT protein CTD PMID:20122984 NCBI chr 2:130,416,432...130,418,974
Ensembl chr 2:130,418,093...130,418,974
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions ISO [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] promotes the reaction [Ethanol results in increased expression of PARP1 mRNA]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of PARP1 mRNA; Ethanol promotes the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of PARP1 mRNA] CTD PMID:36085217 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pcdh10 protocadherin 10 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of PCDH10 mRNA CTD PMID:37567420 NCBI chr 3:45,332,833...45,389,014
Ensembl chr 3:45,332,833...45,390,058
JBrowse link
G Pcdhga8 protocadherin gamma subfamily A, 8 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of PCDHGA8 mRNA CTD PMID:37567420 NCBI chr18:37,858,759...37,974,926
Ensembl chr18:37,858,759...37,974,926
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression
decreases expression
multiple interactions
ISO
EXP
2,4-Dichlorophenoxyacetic Acid results in increased expression of PCNA mRNA
2,4-Dichlorophenoxyacetic Acid results in decreased expression of PCNA protein
[2,4-Dichlorophenoxyacetic Acid co-treated with Glyphosate] promotes the reaction [[lard co-treated with Cholesterol co-treated with Glucose co-treated with Sucrose co-treated with Fructose] results in decreased expression of PCNA protein]; [2,4-Dichlorophenoxyacetic Acid co-treated with Glyphosate] results in decreased expression of PCNA protein; [2,4-Dichlorophenoxyacetic Acid co-treated with lard co-treated with Cholesterol co-treated with Glucose co-treated with Sucrose co-treated with Fructose] results in decreased expression of PCNA protein
CTD PMID:15878651 PMID:37615203 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of PCSK2 mRNA CTD PMID:37567420 NCBI chr 2:143,388,053...143,658,204
Ensembl chr 2:143,388,076...143,658,205
JBrowse link
G Penk preproenkephalin multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of PENK mRNA CTD PMID:37567420 NCBI chr 4:4,133,536...4,138,815
Ensembl chr 4:4,133,531...4,138,819
JBrowse link
G Per3 period circadian clock 3 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of PER3 mRNA CTD PMID:37567420 NCBI chr 4:151,081,475...151,129,167
Ensembl chr 4:151,088,109...151,129,122
JBrowse link
G Pfkm phosphofructokinase, muscle decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of PFKM mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of PFKM protein CTD PMID:23538319 NCBI chr15:97,990,470...98,030,328
Ensembl chr15:97,990,470...98,030,332
JBrowse link
G Phgdh 3-phosphoglycerate dehydrogenase multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of PHGDH mRNA CTD PMID:37567420 NCBI chr 3:98,220,487...98,247,285
Ensembl chr 3:98,220,486...98,247,306
JBrowse link
G Pilrb2 paired immunoglobin-like type 2 receptor beta 2 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of PILRB2 mRNA CTD PMID:37567420 NCBI chr 5:137,864,083...137,870,083
Ensembl chr 5:137,864,089...137,870,077
JBrowse link
G Plxdc1 plexin domain containing 1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of PLXDC1 mRNA CTD PMID:37567420 NCBI chr11:97,814,063...97,879,393
Ensembl chr11:97,814,064...97,877,270
JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of PNPLA3 mRNA CTD PMID:37567420 NCBI chr15:84,052,017...84,073,720
Ensembl chr15:84,052,038...84,071,437
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases response to substance EXP PPARA protein results in increased susceptibility to 2,4-Dichlorophenoxyacetic Acid CTD PMID:26838045 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Ppard peroxisome proliferator activator receptor delta multiple interactions
increases expression
ISO PPARB protein affects the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CREB1 mRNA]; PPARB protein affects the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FOXO1 mRNA]
2,4-Dichlorophenoxyacetic Acid results in increased expression of PPARB mRNA
CTD PMID:29633193 NCBI chr17:28,451,715...28,520,446
Ensembl chr17:28,451,674...28,520,448
JBrowse link
G Prl prolactin decreases secretion ISO 2,4-Dichlorophenoxyacetic Acid results in decreased secretion of PRL protein CTD PMID:20122984 NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188
JBrowse link
G Prok1 prokineticin 1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of PROK1 mRNA CTD PMID:37567420 NCBI chr 3:107,139,232...107,147,023
Ensembl chr 3:107,140,113...107,147,023
JBrowse link
G Prr33 proline rich 33 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of PRR33 mRNA CTD PMID:37567420 NCBI chr 7:142,044,808...142,060,508
Ensembl chr 7:142,044,811...142,060,508
JBrowse link
G Ptger3 prostaglandin E receptor 3 (subtype EP3) decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of PTGER3 mRNA CTD PMID:15878651 NCBI chr 3:157,272,459...157,350,392
Ensembl chr 3:157,272,529...157,351,525
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] promotes the reaction [Ethanol results in increased expression of PTGS2 mRNA]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of PTGS2 mRNA; Ethanol promotes the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of PTGS2 mRNA] CTD PMID:36085217 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Pycard PYD and CARD domain containing multiple interactions
increases expression
ISO lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of PYCARD protein] CTD PMID:34464015 NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039
JBrowse link
G R3hdml R3H domain containing-like multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of R3HDML mRNA CTD PMID:37567420 NCBI chr 2:163,333,364...163,344,532
Ensembl chr 2:163,334,238...163,344,532
JBrowse link
G Rasl12 RAS-like, family 12 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of RASL12 mRNA CTD PMID:37567420 NCBI chr 9:65,305,766...65,323,420
Ensembl chr 9:65,305,788...65,322,135
JBrowse link
G Rbpjl recombination signal binding protein for immunoglobulin kappa J region-like multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of RBPJL mRNA CTD PMID:37567420 NCBI chr 2:164,244,996...164,257,368
Ensembl chr 2:164,245,061...164,257,368
JBrowse link
G Rd3 retinal degeneration 3 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of RD3 mRNA CTD PMID:37567420 NCBI chr 1:191,688,574...191,725,497
Ensembl chr 1:191,709,331...191,720,244
JBrowse link
G Recql4 RecQ protein-like 4 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of RECQL4 mRNA CTD PMID:37567420 NCBI chr15:76,587,753...76,594,820
Ensembl chr15:76,587,753...76,594,748
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] promotes the reaction [Ethanol results in increased expression of RELA mRNA]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of RELA mRNA; Ethanol promotes the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of RELA mRNA] CTD PMID:36085217 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Rmi2 RecQ mediated genome instability 2 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of RMI2 mRNA CTD PMID:37567420 NCBI chr16:10,652,923...10,661,099
Ensembl chr16:10,652,923...10,710,830
JBrowse link
G Rptn repetin multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of RPTN mRNA CTD PMID:37567420 NCBI chr 3:93,301,006...93,306,749
Ensembl chr 3:93,301,006...93,306,749
JBrowse link
G Sbsn suprabasin multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of SBSN mRNA CTD PMID:37567420 NCBI chr 7:30,432,099...30,455,559
Ensembl chr 7:30,450,896...30,455,559
JBrowse link
G Scarna17 small Cajal body-specific RNA 17 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of SCARNA17 mRNA CTD PMID:37567420 NCBI chr18:74,911,465...74,911,526
Ensembl chr18:74,911,462...74,911,540
JBrowse link
G Sik1 salt inducible kinase 1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of SIK1 mRNA CTD PMID:37567420 NCBI chr17:32,063,222...32,074,808
Ensembl chr17:32,063,224...32,074,778
JBrowse link
G Slc16a3 solute carrier family 16 (monocarboxylic acid transporters), member 3 decreases expression
increases expression
ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of SLC16A3 mRNA
2,4-Dichlorophenoxyacetic Acid results in increased expression of SLC16A3 mRNA
CTD PMID:23538319 NCBI chr11:120,839,310...120,849,826
Ensembl chr11:120,839,306...120,851,694
JBrowse link
G Slc22a12 solute carrier family 22 (organic anion/cation transporter), member 12 multiple interactions EXP Potassium promotes the reaction [SLC22A12 protein results in increased uptake of 2,4-Dichlorophenoxyacetic Acid] CTD PMID:15284287 NCBI chr19:6,585,884...6,593,100
Ensembl chr19:6,585,875...6,593,062
JBrowse link
G Slc22a19 solute carrier family 22 (organic anion transporter), member 19 multiple interactions EXP 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [SLC22A19 protein results in increased uptake of ochratoxin A] CTD PMID:15068970 NCBI chr19:7,650,440...7,688,675
Ensembl chr19:7,650,426...7,688,675
JBrowse link
G Slc22a20 solute carrier family 22 (organic anion transporter), member 20 multiple interactions EXP 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [SLC22A20 protein results in increased uptake of estrone sulfate] CTD PMID:16478971 NCBI chr19:6,020,262...6,036,171
Ensembl chr19:6,020,262...6,036,171
JBrowse link
G Slc22a3 solute carrier family 22 (organic cation transporter), member 3 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of SLC22A3 mRNA CTD PMID:37567420 NCBI chr17:12,638,859...12,726,591
Ensembl chr17:12,637,847...12,726,591
JBrowse link
G Slc22a6 solute carrier family 22 (organic anion transporter), member 6 increases uptake
multiple interactions
ISO SLC22A6 protein results in increased uptake of 2,4-Dichlorophenoxyacetic Acid
p-Aminohippuric Acid inhibits the reaction [SLC22A6 protein results in increased uptake of 2,4-Dichlorophenoxyacetic Acid]
CTD PMID:16857889 PMID:17255469 NCBI chr19:8,595,360...8,605,663
Ensembl chr19:8,595,403...8,605,663
JBrowse link
G Slc26a3 solute carrier family 26, member 3 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of SLC26A3 mRNA CTD PMID:37567420 NCBI chr12:31,483,141...31,523,921
Ensembl chr12:31,440,870...31,523,916
JBrowse link
G Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 decreases expression
increases expression
ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of SLC2A3 mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of SLC2A3 protein
2,4-Dichlorophenoxyacetic Acid results in increased expression of SLC2A3 mRNA
CTD PMID:23538319 NCBI chr 6:122,704,783...122,779,149
Ensembl chr 6:122,704,768...122,778,599
JBrowse link
G Smgc submandibular gland protein C multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of SMGC mRNA CTD PMID:37567420 NCBI chr15:91,722,531...91,745,633
Ensembl chr15:91,722,468...91,745,636
JBrowse link
G Sod1 superoxide dismutase 1, soluble decreases activity
multiple interactions
EXP 2,4-Dichlorophenoxyacetic Acid results in decreased activity of SOD1 protein
2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of SOD1 mRNA]
CTD PMID:35099110 PMID:37516258 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of SPP1 mRNA CTD PMID:37567420 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916
JBrowse link
G Spta1 spectrin alpha, erythrocytic 1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of SPTA1 mRNA CTD PMID:37567420 NCBI chr 1:174,000,305...174,076,015
Ensembl chr 1:174,000,342...174,076,016
JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions
ISO
EXP
2,4-Dichlorophenoxyacetic Acid results in increased expression of SQSTM1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of SQSTM1 protein
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of SQSTM1 mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of SQSTM1 protein]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of SQSTM1 mRNA]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of SQSTM1 protein]
CTD PMID:34464015 PMID:35099110 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
JBrowse link
G Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of SRXN1 mRNA CTD PMID:34626751 NCBI chr 2:151,946,738...151,953,296
Ensembl chr 2:151,947,436...151,953,296
JBrowse link
G Stx19 syntaxin 19 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of STX19 mRNA CTD PMID:37567420 NCBI chr16:62,635,039...62,643,085
Ensembl chr16:62,635,039...62,644,709
JBrowse link
G Tbx15 T-box 15 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of TBX15 mRNA CTD PMID:37567420 NCBI chr 3:99,147,671...99,261,576
Ensembl chr 3:99,147,697...99,261,575
JBrowse link
G Tdrd9 tudor domain containing 9 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of TDRD9 mRNA CTD PMID:37567420 NCBI chr12:111,937,922...112,035,288
Ensembl chr12:111,937,993...112,035,288
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] affects the reaction [Ethanol results in increased expression of TGFB1 mRNA]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of TGFB1 mRNA; Ethanol affects the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of TGFB1 mRNA] CTD PMID:36085217 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Th tyrosine hydroxylase increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of TH protein CTD PMID:16931444 NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865
JBrowse link
G Thrb thyroid hormone receptor beta affects binding ISO 2,4-Dichlorophenoxyacetic Acid binds to THRB protein CTD PMID:27410513 NCBI chr14:4,429,599...4,810,538
Ensembl chr14:4,431,611...4,809,435
JBrowse link
G Tjp1 tight junction protein 1 decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of TJP1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of TJP1 protein CTD PMID:28699141 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529
JBrowse link
G Tlcd2 TLC domain containing 2 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of TLCD2 mRNA CTD PMID:37567420 NCBI chr11:75,358,771...75,361,725
Ensembl chr11:75,352,541...75,361,725
JBrowse link
G Tmem232 transmembrane protein 232 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of TMEM232 mRNA CTD PMID:37567420 NCBI chr17:65,562,994...65,848,080
Ensembl chr17:65,562,994...65,847,777
JBrowse link
G Tmem52 transmembrane protein 52 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of TMEM52 mRNA CTD PMID:37567420 NCBI chr 4:155,553,571...155,555,315
Ensembl chr 4:155,553,571...155,555,315
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
EXP
ISO
2,4-Dichlorophenoxyacetic Acid results in increased expression of TNF; 2,4-Dichlorophenoxyacetic Acid results in increased expression of TNF protein
2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of TNF mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of TNF protein]
[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] promotes the reaction [Ethanol results in increased expression of TNF mRNA]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of TNF mRNA; Ethanol promotes the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of TNF mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of TNF protein]
CTD PMID:20728597 PMID:34464015 PMID:35099110 PMID:36085217 PMID:37516258 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of TNFSF14 mRNA CTD PMID:37567420 NCBI chr17:57,496,437...57,501,182
Ensembl chr17:57,496,492...57,501,177
JBrowse link
G Tpsb2 tryptase beta 2 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of TPSB2 mRNA CTD PMID:37567420 NCBI chr17:25,585,282...25,587,070
Ensembl chr17:25,585,170...25,588,079
JBrowse link
G Trbv13-2 T cell receptor beta, variable 13-2 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of TRBV13-2 mRNA CTD PMID:37567420 NCBI chr 6:41,098,330...41,098,766
Ensembl chr 6:41,098,330...41,098,766
JBrowse link
G Trp53 transformation related protein 53 increases expression
multiple interactions
EXP
ISO
2,4-Dichlorophenoxyacetic Acid results in increased expression of TRP53 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of TRP53 protein
[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] promotes the reaction [Ethanol results in increased expression of TP53 mRNA]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of TP53 mRNA; Ethanol promotes the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of TP53 mRNA]
2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of TP53 mRNA]; [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of TRP53 mRNA; [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of TRP53 protein
CTD PMID:33865415 PMID:36085217 PMID:37516258 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Trp73 transformation related protein 73 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of TRP73 mRNA CTD PMID:37567420 NCBI chr 4:154,140,706...154,224,332
Ensembl chr 4:154,140,706...154,224,665
JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of TSKU mRNA CTD PMID:37567420 NCBI chr 7:97,999,875...98,010,602
Ensembl chr 7:97,999,875...98,010,535
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of UGT1A1 mRNA CTD PMID:37567420 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of UGT1A2 mRNA CTD PMID:37567420 NCBI chr 1:88,128,333...88,147,724
Ensembl chr 1:88,128,323...88,146,719
JBrowse link
G Upp2 uridine phosphorylase 2 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of UPP2 mRNA CTD PMID:37567420 NCBI chr 2:58,456,329...58,685,858
Ensembl chr 2:58,457,310...58,682,983
JBrowse link
G Usp19 ubiquitin specific peptidase 19 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of USP19 mRNA CTD PMID:15878651 NCBI chr 9:108,367,806...108,379,536
Ensembl chr 9:108,367,801...108,379,536
JBrowse link
G Vash2 vasohibin 2 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of VASH2 mRNA CTD PMID:37567420 NCBI chr 1:190,679,843...190,711,500
Ensembl chr 1:190,679,843...190,711,493
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of VEGFA mRNA CTD PMID:15878651 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Vmn2r3 vomeronasal 2, receptor 3 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of VMN2R3 mRNA CTD PMID:37567420 NCBI chr 3:64,166,225...64,197,130
Ensembl chr 3:64,164,636...64,197,130
JBrowse link
G Vwa1 von Willebrand factor A domain containing 1 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of VWA1 mRNA CTD PMID:37567420 NCBI chr 4:155,852,952...155,859,042
Ensembl chr 4:155,852,606...155,859,155
JBrowse link
G Wfdc16 WAP four-disulfide core domain 16 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of WFDC16 mRNA CTD PMID:37567420 NCBI chr 2:164,476,621...164,480,728
Ensembl chr 2:164,476,627...164,480,716
JBrowse link
G Xlr3a X-linked lymphocyte-regulated 3A multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of XLR3A mRNA CTD PMID:37567420 NCBI chr  X:72,129,899...72,140,701
Ensembl chr  X:72,129,899...72,140,701
JBrowse link
G Zfand4 zinc finger, AN1-type domain 4 multiple interactions EXP [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of ZFAND4 mRNA CTD PMID:37567420 NCBI chr 6:116,241,046...116,310,384
Ensembl chr 6:116,241,183...116,307,263
JBrowse link
3-(1H-indol-3-yl)propanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl-hydrocarbon receptor multiple interactions ISO 3-(1H-indol-3-yl)propanoic acid inhibits the reaction [indoxyl sulfate increases expression of mRNA, protein] in HK-2 human kidney proximal tubule cell line RGD PMID:29238104 RGD:401793752 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO 3-(1H-indol-3-yl)propanoic acid inhibits the reaction [indoxyl sulfate increases expression of mRNA, protein] in HK-2 human kidney proximal tubule cell line RGD PMID:29238104 RGD:401793752 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO 3-(1H-indol-3-yl)propanoic acid inhibits the reaction [indoxyl sulfate increases expression of mRNA, protein] in HK-2 human kidney proximal tubule cell line RGD PMID:29238104 RGD:401793752 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha increases expression ISO indolepropionic acid analog results in increased expression of NFKBIA protein CTD PMID:23499788 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases cleavage ISO indolepropionic acid analog results in increased cleavage of PARP1 protein CTD PMID:23499788 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO 3-(1H-indol-3-yl)propanoic acid inhibits the reaction [indoxyl sulfate increases expression and increases phosphorylation of Stat3] in HK-2 human kidney proximal tubule cell line RGD PMID:29238104 RGD:401793752 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO 3-(1H-indol-3-yl)propanoic acid inhibits the reaction [indoxyl sulfate increases expression of mRNA, protein] in HK-2 human kidney proximal tubule cell line RGD PMID:29238104 RGD:401793752 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
4'-hydroxydiclofenac term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO 4'-hydroxydiclofenac binds to and affects the activity of AR protein CTD PMID:29777833 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO 4'-hydroxydiclofenac results in increased expression of CCL2 mRNA CTD PMID:24104198 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 increases expression ISO 4'-hydroxydiclofenac results in increased expression of CXCL8 mRNA CTD PMID:24104198 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 increases chemical synthesis
multiple interactions
ISO CYP2C9 protein results in increased chemical synthesis of 4'-hydroxydiclofenac
[[CYP2C9 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased hydroxylation of Diclofenac] which results in increased abundance of 4'-hydroxydiclofenac; [[Ticrynafen results in decreased activity of CYP2C9 protein] which affects the metabolism of Diclofenac] which affects the abundance of 4'-hydroxydiclofenac; [CYP2C9 mRNA results in increased metabolism of Diclofenac] which results in increased chemical synthesis of 4'-hydroxydiclofenac; [CYP2C9 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 4'-hydroxydiclofenac; [CYP2C9 protein results in increased hydroxylation of Diclofenac] which results in increased chemical synthesis of 4'-hydroxydiclofenac; [CYP2C9 protein results in increased metabolism of Diclofenac] which results in increased abundance of 4'-hydroxydiclofenac; [CYP2C9 protein results in increased metabolism of Diclofenac] which results in increased chemical synthesis of 4'-hydroxydiclofenac; Sulfaphenazole inhibits the reaction [[CYP2C9 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 4'-hydroxydiclofenac]
CTD PMID:12401345 PMID:15155557 PMID:24104198 PMID:24246759 PMID:25084468 More... NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 multiple interactions ISO [[CYP2D6 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased hydroxylation of Diclofenac] which results in increased abundance of 4'-hydroxydiclofenac; [CYP2D6 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 4'-hydroxydiclofenac CTD PMID:24246759 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461
JBrowse link
G Esr1 estrogen receptor 1 (alpha) affects activity ISO 4'-hydroxydiclofenac affects the activity of ESR1 protein CTD PMID:29777833 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 increases glutathionylation
multiple interactions
ISO GSTP1 protein results in increased glutathionylation of 4'-hydroxydiclofenac
[[CYP2C9 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased hydroxylation of Diclofenac] which results in increased abundance of 4'-hydroxydiclofenac; [[CYP2D6 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased hydroxylation of Diclofenac] which results in increased abundance of 4'-hydroxydiclofenac; [CYP2C9 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 4'-hydroxydiclofenac; [CYP2D6 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 4'-hydroxydiclofenac; NQO1 protein inhibits the reaction [GSTP1 protein results in increased glutathionylation of 4'-hydroxydiclofenac]; Sulfaphenazole inhibits the reaction [[CYP2C9 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 4'-hydroxydiclofenac]
CTD PMID:24246759 PMID:24552538 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G Il10 interleukin 10 multiple interactions ISO 4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein] CTD PMID:29777833 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il2 interleukin 2 multiple interactions ISO 4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein] CTD PMID:29777833 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il4 interleukin 4 multiple interactions ISO 4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL4 protein] CTD PMID:29777833 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il6 interleukin 6 multiple interactions ISO 4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein] CTD PMID:29777833 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO 4'-hydroxydiclofenac promotes the reaction [[Hydrogen Peroxide co-treated with MPO protein co-treated with Glutathione] results in increased glutathionylation of 5,5-dimethyl-1-pyrroline-1-oxide]; 4'-hydroxydiclofenac promotes the reaction [Hydrogen Peroxide results in increased activity of MPO protein]; [Hydrogen Peroxide results in increased activity of MPO protein] which results in increased oxidation of and results in increased susceptibility to 4'-hydroxydiclofenac CTD PMID:28754375 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions ISO NQO1 protein inhibits the reaction [GSTP1 protein results in increased glutathionylation of 4'-hydroxydiclofenac] CTD PMID:24552538 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide quinone reductase 2 multiple interactions ISO NQO2 protein results in increased reduction of and results in decreased glutathionylation of 4'-hydroxydiclofenac CTD PMID:29281794 NCBI chr13:34,148,642...34,172,448
Ensembl chr13:34,148,670...34,172,426
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO 4'-hydroxydiclofenac binds to and affects the activity of NR3C1 protein CTD PMID:29777833 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474
JBrowse link
G Tnf tumor necrosis factor increases response to substance
multiple interactions
ISO TNF protein results in increased susceptibility to 4'-hydroxydiclofenac
4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]
CTD PMID:23939143 PMID:29777833 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
5-hydroxydiclofenac term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 multiple interactions ISO [CYP2B6 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 5-hydroxydiclofenac CTD PMID:24246759 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 multiple interactions ISO [CYP2C19 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 5-hydroxydiclofenac CTD PMID:24246759 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Cyp2c52-ps cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene multiple interactions ISO [CYP2C18 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 5-hydroxydiclofenac CTD PMID:24246759 NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733
JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 multiple interactions ISO [CYP2D6 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 5-hydroxydiclofenac CTD PMID:24246759 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461
JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 multiple interactions ISO [CYP3A5 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 5-hydroxydiclofenac CTD PMID:24246759 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 multiple interactions ISO [[CYP3A4 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased hydroxylation of Diclofenac] which results in increased abundance of 5-hydroxydiclofenac; [CYP2B6 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 5-hydroxydiclofenac; [CYP2C18 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 5-hydroxydiclofenac; [CYP2C19 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 5-hydroxydiclofenac; [CYP2D6 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 5-hydroxydiclofenac; [CYP3A4 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 5-hydroxydiclofenac; [CYP3A5 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 5-hydroxydiclofenac; Ketoconazole inhibits the reaction [[CYP3A4 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 5-hydroxydiclofenac] CTD PMID:24246759 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO [Hydrogen Peroxide results in increased activity of MPO protein] which results in increased oxidation of and results in increased susceptibility to 5-hydroxydiclofenac CTD PMID:28754375 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
aceclofenac term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 a disintegrin and metallopeptidase domain 17 increases response to substance EXP ADAM17 results in increased susceptibility to aceclofenac CTD PMID:12147693 NCBI chr12:21,373,510...21,423,633
Ensembl chr12:21,373,510...21,423,633
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO
EXP
aceclofenac results in increased expression of GDF15 protein
aceclofenac results in increased expression of GDF15 mRNA
CTD PMID:15555568 PMID:18076062 NCBI chr 8:71,082,043...71,085,106
Ensembl chr 8:71,082,043...71,085,106
JBrowse link
G Sell selectin, lymphocyte decreases expression ISO aceclofenac results in decreased expression of SELL protein CTD PMID:12147693 NCBI chr 1:163,889,556...163,908,354
Ensembl chr 1:163,889,551...163,911,750
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [aceclofenac co-treated with Lipopolysaccharides] results in increased secretion of TNF protein CTD PMID:17328244 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
atropine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP-binding cassette, sub-family B member 11 multiple interactions
decreases activity
ISO Atropine inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Atropine results in decreased activity of ABCB11 protein
CTD PMID:24014644 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958
JBrowse link
G Abl1 c-abl oncogene 1, non-receptor tyrosine kinase multiple interactions ISO [Parathion co-treated with Atropine] results in increased expression of ABL1 mRNA CTD PMID:17390078 NCBI chr 2:31,578,256...31,697,105
Ensembl chr 2:31,578,388...31,694,239
JBrowse link
G Ache acetylcholinesterase multiple interactions ISO
EXP
Atropine inhibits the reaction [[Organophosphorus Compounds results in decreased activity of ACHE protein] which results in increased abundance of Acetylcholine]; Atropine inhibits the reaction [Carbachol results in increased metabolism of and results in increased secretion of ACHE protein]; Atropine inhibits the reaction [Paraoxon results in increased expression of ACHE protein]
[Atropine co-treated with Obidoxime Chloride] inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]; [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of ACHE protein; [Paraoxon co-treated with pralidoxime co-treated with Atropine] results in decreased activity of ACHE protein; [pralidoxime co-treated with Atropine] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; [tariquidar co-treated with asoxime chloride co-treated with Atropine] inhibits the reaction [Soman results in decreased activity of ACHE protein]; Atropine inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [[Paraoxon co-treated with pralidoxime co-treated with Atropine] results in decreased activity of ACHE protein]; pralidoxime promotes the reaction [[Atropine co-treated with Curcumin] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]]
[1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [[1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with cucurbit(7)uril] co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Atropine inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Atropine promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; Atropine promotes the reaction [haloxon results in increased phosphorylation of ACHE protein]; Atropine promotes the reaction [Paraoxon results in increased phosphorylation of ACHE protein]
CTD PMID:2241428 PMID:10421444 PMID:17963125 PMID:20105433 PMID:21600273 More... NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Adcy5 adenylate cyclase 5 increases response to substance EXP ADCY5 protein results in increased susceptibility to Atropine CTD PMID:12869393 NCBI chr16:34,974,933...35,126,108
Ensembl chr16:34,975,247...35,126,108
JBrowse link
G Aqp5 aquaporin 5 multiple interactions EXP Atropine inhibits the reaction [Pilocarpine affects the localization of AQP5 protein] CTD PMID:26208470 NCBI chr15:99,488,909...99,492,710
Ensembl chr15:99,488,663...99,492,710
JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the expression of BAX mRNA] CTD PMID:21971501 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcar1 breast cancer anti-estrogen resistance 1 multiple interactions ISO Atropine inhibits the reaction [[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of BCAR1 protein]] CTD PMID:10537051 NCBI chr 8:112,437,106...112,470,481
Ensembl chr 8:112,437,106...112,470,441
JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO [Atropine co-treated with pralidoxime] results in decreased expression of BCHE protein; [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of BCHE protein
[BCHE protein co-treated with asoxime chloride co-treated with pro-diazepam co-treated with Atropine] results in decreased susceptibility to VX-agent
CTD PMID:17963125 PMID:22981459 NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748
JBrowse link
G Bdkrb2 bradykinin receptor, beta 2 multiple interactions EXP BDKRB2 affects the susceptibility to [Propranolol co-treated with Atropine] CTD PMID:10614985 NCBI chr12:105,529,431...105,561,503
Ensembl chr12:105,529,485...105,561,496
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO Atropine inhibits the reaction [Carbon Tetrachloride results in increased expression of BMP6 mRNA] CTD PMID:18472332 NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278
JBrowse link
G Cacna1e calcium channel, voltage-dependent, R type, alpha 1E subunit multiple interactions ISO Atropine inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]] CTD PMID:12663092 NCBI chr 1:154,266,552...154,760,374
Ensembl chr 1:154,266,477...154,760,247
JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha affects activity ISO Atropine affects the activity of CALCA protein CTD PMID:7906887 PMID:10075105 NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592
JBrowse link
G Casp3 caspase 3 increases expression ISO Atropine results in increased expression of CASP3 mRNA CTD PMID:19815060 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CCL5 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CCL5 protein] CTD PMID:22245128 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Ccna1 cyclin A1 increases expression
multiple interactions
ISO Atropine results in increased expression of CCNA1 mRNA
[Parathion co-treated with Atropine] results in increased expression of CCNA1 mRNA
CTD PMID:17390078 NCBI chr 3:54,952,890...54,965,055
Ensembl chr 3:54,952,890...54,962,922
JBrowse link
G Ccnd3 cyclin D3 multiple interactions ISO [Parathion co-treated with Atropine] results in increased expression of CCND3 mRNA CTD PMID:17390078 NCBI chr17:47,815,976...47,910,614
Ensembl chr17:47,815,976...47,910,616
JBrowse link
G Ccne1 cyclin E1 increases expression
multiple interactions
ISO Atropine results in increased expression of CCNE1 mRNA
[Parathion co-treated with Atropine] results in increased expression of CCNE1 mRNA
CTD PMID:17390078 NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959
JBrowse link
G Ccne2 cyclin E2 multiple interactions
increases expression
ISO [Parathion co-treated with Atropine] results in increased expression of CCNE2 mRNA
Atropine results in increased expression of CCNE2 mRNA
CTD PMID:17390078 NCBI chr 4:11,190,489...11,204,781
Ensembl chr 4:11,191,351...11,204,779
JBrowse link
G Cd40 CD40 antigen multiple interactions ISO Atropine inhibits the reaction [Carbachol results in increased expression of CD40 protein] CTD PMID:16879495 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868
JBrowse link
G Cdc20 cell division cycle 20 multiple interactions
increases expression
ISO [Parathion co-treated with Atropine] results in increased expression of CDC20 mRNA
Atropine results in increased expression of CDC20 mRNA
CTD PMID:17390078 NCBI chr 4:118,290,098...118,294,540
Ensembl chr 4:118,290,098...118,294,549
JBrowse link
G Cdc6 cell division cycle 6 multiple interactions ISO [Parathion co-treated with Atropine] results in increased expression of CDC6 mRNA CTD PMID:17390078 NCBI chr11:98,798,627...98,814,768
Ensembl chr11:98,798,627...98,814,766
JBrowse link
G Cdk1 cyclin dependent kinase 1 multiple interactions
increases expression
ISO [Parathion co-treated with Atropine] results in increased expression of CDK1 mRNA
Atropine results in increased expression of CDK1 mRNA
CTD PMID:17390078 NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768
JBrowse link
G Ces1d carboxylesterase 1D multiple interactions ISO Atropine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate] CTD PMID:9311626 NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1, CNS multiple interactions
decreases activity
EXP
ISO
Atropine binds to and results in decreased activity of CHRM1 protein; Atropine inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]
Atropine results in decreased activity of CHRM1 protein
Atropine affects the reaction [muscarinic toxin 7 binds to CHRM1 protein]
CTD PMID:16439611 PMID:18316702 PMID:31830555 NCBI chr19:8,641,369...8,660,970
Ensembl chr19:8,641,153...8,660,951
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2, cardiac multiple interactions ISO Atropine binds to and results in decreased activity of CHRM2 protein CTD PMID:15140916 NCBI chr 6:36,364,928...36,505,573
Ensembl chr 6:36,365,019...36,505,349
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3, cardiac multiple interactions
decreases activity
ISO Atropine binds to and results in decreased activity of CHRM3 protein; Atropine inhibits the reaction [Carbachol results in increased activity of CHRM3 protein]
Atropine results in decreased activity of CHRM3 protein
CTD PMID:15140916 PMID:20708676 PMID:31830555 NCBI chr13:9,925,522...10,411,131
Ensembl chr13:9,925,522...10,410,883
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 multiple interactions
affects binding
ISO [WIN 62577 co-treated with Quinuclidinyl Benzilate] inhibits the reaction [Atropine binds to CHRM4 protein] CTD PMID:16709648 NCBI chr 2:91,752,531...91,760,180
Ensembl chr 2:91,757,594...91,759,033
JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 multiple interactions ISO Atropine inhibits the reaction [Acetylcholine results in increased activity of CHRM5 protein] CTD PMID:31323226 NCBI chr 2:112,306,055...112,365,487
Ensembl chr 2:112,309,516...112,311,114
JBrowse link
G Chrna4 cholinergic receptor, nicotinic, alpha polypeptide 4 multiple interactions
affects binding
ISO Atropine promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]
Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNA4 mRNA]]; Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNA4 protein]]
Atropine binds to [CHRNA4 protein binds to CHRNB2 protein]
CTD PMID:15733544 PMID:21791372 NCBI chr 2:180,664,104...180,685,339
Ensembl chr 2:180,660,173...180,685,339
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit affects binding
multiple interactions
ISO Atropine binds to [CHRNA4 protein binds to CHRNB2 protein]
Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNB2 mRNA]]; Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNB2 protein]]
Atropine promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]
CTD PMID:15733544 PMID:21791372 NCBI chr 3:89,660,755...89,671,939
Ensembl chr 3:89,653,502...89,671,939
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of CREB1 protein] CTD PMID:21971501 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Crh corticotropin releasing hormone multiple interactions ISO Atropine inhibits the reaction [acephate results in increased expression of CRH mRNA]; Atropine inhibits the reaction [acephate results in increased secretion of CRH protein]; Atropine inhibits the reaction [methamidophos results in increased expression of CRH mRNA]; Atropine inhibits the reaction [methamidophos results in increased secretion of CRH protein]
[Atropine co-treated with SR 140333 co-treated with SR 48968] results in decreased activity of CRH protein
CTD PMID:12039681 PMID:12906840 NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of CTNNB1 protein mutant form]; Atropine inhibits the reaction [Parathion results in increased expression of CTNNB1 protein] CTD PMID:17390078 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CXCL1 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CXCL1 protein] CTD PMID:22245128 NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459
JBrowse link
G Dvl2 dishevelled segment polarity protein 2 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of DVL2 protein] CTD PMID:17390078 NCBI chr11:69,891,418...69,900,935
Ensembl chr11:69,891,421...69,903,127
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO EDN1 protein results in decreased activity of [Atropine co-treated with Histamine] CTD PMID:12906840 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 multiple interactions ISO atropine inhibits the reaction [carbachol decreases phosphorylation of EEF2 protein in colon cancer cells] RGD PMID:31227218 RGD:153298919 NCBI chr10:81,012,465...81,018,343
Ensembl chr10:81,012,465...81,018,332
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of EGFR protein] CTD PMID:17390078 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO Atropine inhibits the reaction [Pilocarpine results in increased expression of EGR1 mRNA] CTD PMID:7968354 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Egr2 early growth response 2 multiple interactions ISO Atropine inhibits the reaction [Pilocarpine results in increased expression of EGR2 mRNA] CTD PMID:7968354 NCBI chr10:67,370,334...67,383,354
Ensembl chr10:67,371,305...67,378,018
JBrowse link
G Ezr ezrin multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of EZR protein] CTD PMID:17390078 NCBI chr17:7,005,530...7,050,179
Ensembl chr17:7,005,440...7,050,183
JBrowse link
G F2 coagulation factor II multiple interactions EXP [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in decreased expression of F2 mRNA; [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in increased activity of F2 protein CTD PMID:30515700 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F2r coagulation factor II thrombin receptor multiple interactions EXP [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in increased expression of F2R protein CTD PMID:30515700 NCBI chr13:95,738,288...95,754,974
Ensembl chr13:95,738,311...95,754,995
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression
multiple interactions
ISO Atropine results in increased expression of FOS protein
Atropine inhibits the reaction [Paraoxon results in increased expression of FOS mRNA]
[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased expression of FOS protein]; Atropine inhibits the reaction [Pilocarpine results in increased expression of FOS mRNA]
CTD PMID:7968354 PMID:8281324 PMID:21787676 PMID:21971501 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Ghrl ghrelin multiple interactions ISO Atropine inhibits the reaction [[Pentobarbital co-treated with L-pyroglutamyl-L-histidyl-3,3-dimethylprolinamide] results in increased expression of GHRL protein] CTD PMID:16959836 NCBI chr 6:113,693,080...113,696,872
Ensembl chr 6:113,693,080...113,696,841
JBrowse link
G Glra1 glycine receptor, alpha 1 subunit multiple interactions ISO Atropine binds to and results in decreased activity of GLRA1 protein CTD PMID:15081878 NCBI chr11:55,405,065...55,499,024
Ensembl chr11:55,405,064...55,499,024
JBrowse link
G Grm4 glutamate receptor, metabotropic 4 multiple interactions ISO Atropine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium] CTD PMID:18171729 NCBI chr17:27,641,361...27,732,800
Ensembl chr17:27,641,361...27,740,377
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of ICAM1 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of ICAM1 protein] CTD PMID:22245128 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of IL1B mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of IL1B protein] CTD PMID:22245128 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions EXP [Atropine co-treated with Ketamine] inhibits the reaction [Soman results in increased expression of IL6 mRNA]; [Atropine co-treated with Ketamine] inhibits the reaction [Soman results in increased expression of IL6 protein] CTD PMID:22245128 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Jun jun proto-oncogene multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of JUN protein] CTD PMID:21971501 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Junb jun B proto-oncogene multiple interactions ISO Atropine inhibits the reaction [Pilocarpine results in increased expression of JUNB mRNA] CTD PMID:7968354 NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347
JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 multiple interactions ISO Atropine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium] CTD PMID:18171729 NCBI chr 2:55,301,814...55,488,157
Ensembl chr 2:55,325,982...55,488,157
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of KIT protein] CTD PMID:17390078 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382
JBrowse link
G Ltf lactotransferrin multiple interactions ISO Atropine inhibits the reaction [methylcholine results in increased secretion of LTF protein] CTD PMID:11112886 NCBI chr 9:110,848,360...110,871,834
Ensembl chr 9:110,848,339...110,871,835
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK1 protein] CTD PMID:21971501 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK14 protein] CTD PMID:21971501 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK3 protein] CTD PMID:21971501 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein] CTD PMID:21971501 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 multiple interactions
increases expression
ISO [Parathion co-treated with Atropine] results in increased expression of MCM4 mRNA
Atropine results in increased expression of MCM4 mRNA
CTD PMID:17390078 NCBI chr16:15,441,761...15,455,264
Ensembl chr16:15,441,761...15,455,264
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression
multiple interactions
ISO Atropine results in increased expression of MCM6 mRNA
[Parathion co-treated with Atropine] results in increased expression of MCM6 mRNA
CTD PMID:17390078 NCBI chr 1:128,259,312...128,287,442
Ensembl chr 1:128,259,327...128,287,401
JBrowse link
G Nefh neurofilament, heavy polypeptide affects expression ISO Atropine affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr11:4,888,754...4,898,064
Ensembl chr11:4,888,754...4,898,064
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression ISO Atropine results in increased expression of NLRP3 mRNA CTD PMID:28138970 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions ISO Atropine inhibits the reaction [Indomethacin results in increased activity of NOS2 protein]; Atropine inhibits the reaction [Indomethacin results in increased expression of NOS2 mRNA] CTD PMID:15610444 PMID:16944022 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Notch4 notch 4 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of NOTCH4 protein] CTD PMID:17390078 NCBI chr17:34,783,257...34,807,517
Ensembl chr17:34,783,242...34,807,477
JBrowse link
G Nppa natriuretic peptide type A affects activity ISO Atropine affects the activity of NPPA protein modified form CTD PMID:1363893 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536
JBrowse link
G Oprl1 opioid receptor-like 1 multiple interactions ISO Atropine inhibits the reaction [PNOC protein binds to and results in increased activity of OPRL1 protein] CTD PMID:12007927 NCBI chr 2:181,356,585...181,362,778
Ensembl chr 2:181,356,809...181,362,778
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO Atropine inhibits the reaction [Malathion results in increased expression of PCNA]; Atropine inhibits the reaction [Parathion results in increased expression of PCNA] CTD PMID:12762645 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
JBrowse link
G Pnoc prepronociceptin multiple interactions ISO Atropine inhibits the reaction [PNOC protein binds to and results in increased activity of OPRL1 protein] CTD PMID:12007927 NCBI chr14:65,638,931...65,662,908
Ensembl chr14:65,638,122...65,662,921
JBrowse link
G Pomc pro-opiomelanocortin-alpha multiple interactions ISO Atropine inhibits the reaction [Acetylcholine results in increased expression of POMC protein] CTD PMID:7588217 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP [Atropine co-treated with Glucose] binds to PPARA protein; Atropine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]] CTD PMID:18812576 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Atropine affects the reaction [Indomethacin results in increased expression of PTGS2]; Atropine inhibits the reaction [Indomethacin results in increased expression of PTGS2 mRNA]; Atropine inhibits the reaction [Indomethacin results in increased expression of PTGS2]; Atropine inhibits the reaction [SC 560 results in increased expression of PTGS2 mRNA] CTD PMID:15104355 PMID:15610444 PMID:16259740 PMID:16804302 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 multiple interactions ISO Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein]]; Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[wortmannin co-treated with oxophenylarsine] results in increased phosphorylation of PTK2 protein]]; Atropine inhibits the reaction [oxotremorine M promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with wortmannin] results in increased phosphorylation of PTK2 protein]] CTD PMID:10537051 NCBI chr15:73,076,951...73,297,192
Ensembl chr15:73,076,951...73,295,129
JBrowse link
G Pxn paxillin multiple interactions ISO Atropine inhibits the reaction [[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of PXN protein]] CTD PMID:10537051 NCBI chr 5:115,630,035...115,694,046
Ensembl chr 5:115,644,735...115,694,046
JBrowse link
G Rac3 Rac family small GTPase 3 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of RAC3 protein] CTD PMID:17390078 NCBI chr11:120,612,294...120,614,795
Ensembl chr11:120,612,296...120,614,795
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of RELA protein] CTD PMID:21971501 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of RHOA protein] CTD PMID:17390078 NCBI chr 9:108,183,359...108,215,142
Ensembl chr 9:108,183,328...108,215,133
JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 multiple interactions ISO Atropine inhibits the reaction [SLC22A1 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Atropine inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:16263091 PMID:21641380 NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Atropine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Atropine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]; Atropine inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:16263091 PMID:21599003 PMID:23770354 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
G Slc22a3 solute carrier family 22 (organic cation transporter), member 3 increases uptake
multiple interactions
ISO SLC22A3 protein results in increased uptake of Atropine
Atropine inhibits the reaction [SLC22A3 protein results in increased transport of 1-Methyl-4-phenylpyridinium]
CTD PMID:16263091 NCBI chr17:12,638,859...12,726,591
Ensembl chr17:12,637,847...12,726,591
JBrowse link
G Slc22a4 solute carrier family 22 (organic cation transporter), member 4 multiple interactions ISO Atropine inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 NCBI chr11:53,873,941...53,920,866
Ensembl chr11:53,873,949...53,918,916
JBrowse link
G Slc47a1 solute carrier family 47, member 1 multiple interactions ISO Atropine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr11:61,234,226...61,269,668
Ensembl chr11:61,234,227...61,269,171
JBrowse link
G Slc47a2 solute carrier family 47, member 2 multiple interactions ISO Atropine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr11:61,192,453...61,233,686
Ensembl chr11:61,192,457...61,233,686
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Atropine results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 2:164,195,990...164,231,086
Ensembl chr 2:164,195,990...164,231,015
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of SOCS3 mRNA] CTD PMID:22245128 NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873
JBrowse link
G Spn sialophorin increases response to substance EXP SPN protein results in increased susceptibility to Atropine CTD PMID:18711009 NCBI chr 7:126,731,404...126,743,785
Ensembl chr 7:126,731,404...126,736,995
JBrowse link
G Tat tyrosine aminotransferase multiple interactions ISO [Atropine co-treated with Obidoxime Chloride co-treated with Diazepam] inhibits the reaction [Dichlorvos results in increased expression of TAT protein] CTD PMID:7761789 NCBI chr 8:110,712,710...110,726,436
Ensembl chr 8:110,717,069...110,726,435
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO Atropine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA] CTD PMID:18472332 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of TNF mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of TNF protein] CTD PMID:22245128 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Trio triple functional domain (PTPRF interacting) multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of TRIO protein] CTD PMID:17390078 NCBI chr15:27,730,735...28,025,954
Ensembl chr15:27,730,737...28,025,934
JBrowse link
G Trp53 transformation related protein 53 multiple interactions ISO Atropine inhibits the reaction [Malathion results in increased expression of TP53 protein]; Atropine inhibits the reaction [Parathion results in increased expression of TP53 protein] CTD PMID:12762645 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 decreases response to substance EXP TRPA1 gene mutant form results in decreased susceptibility to Atropine CTD PMID:29627347 NCBI chr 1:14,942,868...14,989,086
Ensembl chr 1:14,942,872...14,989,086
JBrowse link
G Tshb thyroid stimulating hormone, beta subunit multiple interactions ISO [pralidoxime co-treated with Atropine] inhibits the reaction [methamidophos results in decreased expression of TSHB protein] CTD PMID:15891268 NCBI chr 3:102,684,621...102,718,175
Ensembl chr 3:102,682,781...102,690,034
JBrowse link
G Tspo translocator protein multiple interactions ISO [Ketamine co-treated with Midazolam co-treated with Valproic Acid] inhibits the reaction [[Sarin co-treated with [Atropine co-treated with trimethylene-bis(4-hydroxyiminomethylpyridinium)]] results in increased expression of TSPO protein]; [Sarin co-treated with [Atropine co-treated with trimethylene-bis(4-hydroxyiminomethylpyridinium)]] results in increased expression of TSPO protein CTD PMID:33823148 NCBI chr15:83,447,774...83,458,404
Ensembl chr15:83,447,793...83,458,404
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of VCAM1 mRNA] CTD PMID:22245128 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
dicamba term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl increases activity ISO Dicamba results in increased activity of ACOX1 protein CTD PMID:7657066 NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO Dicamba inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein] CTD PMID:29782964 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
JBrowse link
G Alb albumin multiple interactions ISO [bentazone co-treated with Dicamba] results in increased secretion of ALB protein CTD PMID:25863332 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
JBrowse link
G Ebf2 early B cell factor 2 multiple interactions ISO [Herbicides results in increased abundance of Dicamba] which affects the methylation of EBF2 gene CTD PMID:34516295 NCBI chr14:67,470,741...67,668,401
Ensembl chr14:67,470,741...67,668,367
JBrowse link
G Ins2 insulin II multiple interactions ISO Dicamba inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein] CTD PMID:29782964 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
JBrowse link
G Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) increases expression EXP Dicamba results in increased expression of SRXN1 mRNA CTD PMID:34626751 NCBI chr 2:151,946,738...151,953,296
Ensembl chr 2:151,947,436...151,953,296
JBrowse link
diclofenac term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin increases expression EXP Diclofenac results in increased expression of A2M mRNA; Diclofenac results in increased expression of A2ML1 mRNA CTD PMID:26934552 NCBI chr 6:121,612,920...121,656,197
Ensembl chr 6:121,612,335...121,656,186
JBrowse link
G Aacs acetoacetyl-CoA synthetase decreases expression EXP Diclofenac results in decreased expression of AACS mRNA CTD PMID:26934552 NCBI chr 5:125,552,937...125,594,469
Ensembl chr 5:125,552,878...125,594,474
JBrowse link
G Aars1 alanyl-tRNA synthetase 1 decreases expression EXP Diclofenac results in decreased expression of AARS1 mRNA CTD PMID:35537566 NCBI chr 8:111,759,781...111,784,237
Ensembl chr 8:111,759,776...111,784,296
JBrowse link
G Abcb11 ATP-binding cassette, sub-family B member 11 multiple interactions
decreases activity
ISO
EXP
Diclofenac inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in decreased expression of ABCB11 mRNA; Sodium Selenite promotes the reaction [[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in decreased expression of ABCB11 mRNA]
Diclofenac results in decreased activity of ABCB11 protein
CTD PMID:24014644 PMID:28437613 PMID:38945390 PMID:39023798 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958
JBrowse link
G Abcb1a ATP-binding cassette, sub-family B member 1A decreases activity
decreases response to substance
increases expression
EXP
ISO
Diclofenac results in decreased activity of ABCB1A protein
ABCB1A gene mutant form results in decreased susceptibility to Diclofenac
Diclofenac results in increased expression of ABCB1B mRNA
CTD PMID:15458769 PMID:19022234 PMID:28193520 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B decreases expression ISO Diclofenac results in decreased expression of ABCB1B mRNA CTD PMID:19022234 NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315
JBrowse link
G Abcb4 ATP-binding cassette, sub-family B member 4 decreases expression
decreases activity
ISO Diclofenac results in decreased expression of ABCB4 mRNA
Diclofenac results in decreased activity of ABCB4 protein
CTD PMID:19022234 PMID:28437613 NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231
JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 decreases activity
increases expression
multiple interactions
ISO Diclofenac results in decreased activity of ABCC2 protein
Diclofenac results in increased expression of ABCC2 mRNA
ABCC2 protein results in increased transport of and results in increased metabolism of and results in increased susceptibility to Diclofenac
CTD PMID:19022234 PMID:22646477 PMID:25450747 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 decreases activity ISO Diclofenac results in decreased activity of ABCC3 protein CTD PMID:39023798 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823
JBrowse link
G Abcc4 ATP-binding cassette, sub-family C member 4 affects expression ISO Diclofenac affects the expression of ABCC4 mRNA CTD PMID:24752500 NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631
JBrowse link
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase affects expression ISO Diclofenac affects the expression of ABL2 mRNA CTD PMID:24752500 NCBI chr 1:156,386,160...156,477,189
Ensembl chr 1:156,386,356...156,477,138
JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression ISO Diclofenac results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416
JBrowse link
G Acin1 apoptotic chromatin condensation inducer 1 affects expression ISO Diclofenac affects the expression of ACIN1 mRNA CTD PMID:24752500 NCBI chr14:54,879,618...54,924,422
Ensembl chr14:54,879,618...54,924,388
JBrowse link
G Ackr3 atypical chemokine receptor 3 decreases expression ISO Diclofenac results in decreased expression of ACKR3 mRNA CTD PMID:19192274 NCBI chr 1:90,131,702...90,143,446
Ensembl chr 1:90,131,702...90,144,473
JBrowse link
G Acot2 acyl-CoA thioesterase 2 decreases expression EXP Diclofenac results in decreased expression of ACOT2 mRNA CTD PMID:26934552 NCBI chr12:84,034,635...84,040,651
Ensembl chr12:84,034,635...84,040,647
JBrowse link
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl increases expression ISO Diclofenac results in increased expression of ACOX1 mRNA CTD PMID:19022234 NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871
JBrowse link
G Acp3 acid phosphatase 3 increases expression EXP Diclofenac results in increased expression of ACP3 mRNA CTD PMID:26934552 NCBI chr 9:104,165,439...104,214,921
Ensembl chr 9:104,165,450...104,214,947
JBrowse link
G Acta1 actin alpha 1, skeletal muscle affects expression ISO Diclofenac affects the expression of ACTA1 mRNA CTD PMID:24752500 NCBI chr 8:124,618,497...124,621,514
Ensembl chr 8:124,618,508...124,621,490
JBrowse link
G Actl9 actin-like 9 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of ACTL9 mRNA CTD PMID:37844793 NCBI chr17:33,651,873...33,653,242
Ensembl chr17:33,651,870...33,653,242
JBrowse link
G Actn1 actinin, alpha 1 affects expression ISO Diclofenac affects the expression of ACTN1 mRNA CTD PMID:19022234 NCBI chr12:80,214,316...80,307,165
Ensembl chr12:80,214,321...80,307,145
JBrowse link
G Acvr1 activin A receptor, type 1 affects expression ISO Diclofenac affects the expression of ACVR1 mRNA CTD PMID:24752500 NCBI chr 2:58,336,450...58,456,840
Ensembl chr 2:58,278,656...58,457,169
JBrowse link
G Acvr1b activin A receptor, type 1B affects expression
multiple interactions
ISO
EXP
Diclofenac affects the expression of ACVR1B mRNA
[Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in increased expression of ACVR1B mRNA
CTD PMID:24752500 PMID:37844793 NCBI chr15:101,071,953...101,111,565
Ensembl chr15:101,071,948...101,111,565
JBrowse link
G Acvr2b activin receptor IIB affects expression ISO Diclofenac affects the expression of ACVR2B mRNA CTD PMID:24752500 NCBI chr 9:119,231,081...119,271,214
Ensembl chr 9:119,231,184...119,264,061
JBrowse link
G Adamdec1 ADAM-like, decysin 1 increases expression EXP Diclofenac results in increased expression of ADAMDEC1 mRNA CTD PMID:26934552 NCBI chr14:68,800,829...68,819,535
Ensembl chr14:68,800,829...68,819,544
JBrowse link
G Adcy6 adenylate cyclase 6 affects expression ISO Diclofenac affects the expression of ADCY6 mRNA CTD PMID:24752500 NCBI chr15:98,484,982...98,508,119
Ensembl chr15:98,487,854...98,507,957
JBrowse link
G Adcy9 adenylate cyclase 9 affects expression
decreases expression
ISO
EXP
Diclofenac affects the expression of ADCY9 mRNA
Diclofenac results in decreased expression of ADCY9 mRNA
CTD PMID:24752500 PMID:26934552 NCBI chr16:4,102,750...4,255,094
Ensembl chr16:4,105,393...4,238,362
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) increases expression ISO Diclofenac results in increased expression of ADH1 protein CTD PMID:25772430 NCBI chr 3:137,983,346...137,996,459
Ensembl chr 3:137,966,752...137,996,459
JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide decreases expression EXP Diclofenac results in decreased expression of ADH7 mRNA CTD PMID:35537566 NCBI chr 3:137,903,828...137,937,803
Ensembl chr 3:137,923,521...137,939,143
JBrowse link
G Adk adenosine kinase increases expression
decreases expression
ISO Diclofenac results in increased expression of ADK mRNA
Diclofenac results in decreased expression of ADK mRNA
CTD PMID:19022234 NCBI chr14:21,102,622...21,498,637
Ensembl chr14:21,102,642...21,498,637
JBrowse link
G Adora2a adenosine A2a receptor increases expression EXP Diclofenac results in increased expression of ADORA2A mRNA CTD PMID:26934552 NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618
JBrowse link
G Adora2b adenosine A2b receptor increases expression EXP Diclofenac results in increased expression of ADORA2B mRNA CTD PMID:26934552 NCBI chr11:62,139,810...62,157,278
Ensembl chr11:62,139,810...62,157,279
JBrowse link
G Adrb2 adrenergic receptor, beta 2 increases expression EXP Diclofenac results in increased expression of ADRB2 mRNA CTD PMID:26934552 NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030
JBrowse link
G Aen apoptosis enhancing nuclease increases expression EXP Diclofenac results in increased expression of AEN mRNA CTD PMID:35537566 NCBI chr 7:78,545,675...78,560,957
Ensembl chr 7:78,545,602...78,560,957
JBrowse link
G Ager advanced glycosylation end product-specific receptor increases expression EXP
ISO
Diclofenac results in increased expression of AGER mRNA CTD PMID:24747151 PMID:28138970 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910
JBrowse link
G Aggf1 angiogenic factor with G patch and FHA domains 1 affects expression ISO Diclofenac affects the expression of AGGF1 mRNA CTD PMID:24752500 NCBI chr13:95,487,191...95,511,865
Ensembl chr13:95,487,191...95,511,860
JBrowse link
G Ago2 argonaute RISC catalytic subunit 2 affects expression ISO Diclofenac affects the expression of AGO2 mRNA CTD PMID:24752500 NCBI chr15:72,967,693...73,056,777
Ensembl chr15:72,967,693...73,056,784
JBrowse link
G Ago3 argonaute RISC catalytic subunit 3 affects expression ISO Diclofenac affects the expression of AGO3 mRNA CTD PMID:24752500 NCBI chr 4:126,220,797...126,323,360
Ensembl chr 4:126,225,497...126,323,349
JBrowse link
G Ago4 argonaute RISC catalytic subunit 4 affects expression ISO Diclofenac affects the expression of AGO4 mRNA CTD PMID:24752500 NCBI chr 4:126,383,280...126,427,379
Ensembl chr 4:126,383,334...126,427,265
JBrowse link
G Agrp agouti related neuropeptide increases expression ISO Diclofenac results in increased expression of AGRP mRNA CTD PMID:30723492 NCBI chr 8:106,293,327...106,306,477
Ensembl chr 8:106,293,330...106,364,025
JBrowse link
G Ahr aryl-hydrocarbon receptor increases expression EXP Diclofenac results in increased expression of AHR mRNA CTD PMID:26934552 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
JBrowse link
G Ahsg alpha-2-HS-glycoprotein multiple interactions ISO [Diclofenac co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of AHSG protein CTD PMID:25772430 NCBI chr16:22,710,793...22,718,193
Ensembl chr16:22,710,027...22,718,199
JBrowse link
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 affects expression ISO Diclofenac affects the expression of AIFM1 mRNA CTD PMID:24752500 NCBI chr  X:47,563,821...47,602,440
Ensembl chr  X:47,563,821...47,602,440
JBrowse link
G Aim2 absent in melanoma 2 increases expression EXP Diclofenac results in increased expression of AIM2 mRNA CTD PMID:26934552 NCBI chr 1:173,177,105...173,293,606
Ensembl chr 1:173,178,445...173,293,606
JBrowse link
G Akna AT-hook transcription factor decreases expression EXP Diclofenac results in decreased expression of AKNA mRNA CTD PMID:35537566 NCBI chr 4:63,285,364...63,328,988
Ensembl chr 4:63,285,362...63,321,591
JBrowse link
G Akr1b7 aldo-keto reductase family 1, member B7 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of AKR1B7 mRNA CTD PMID:37844793 NCBI chr 6:34,389,297...34,400,072
Ensembl chr 6:34,389,269...34,400,077
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 affects expression ISO Diclofenac affects the expression of AKT1 mRNA CTD PMID:24752500 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Akt2 thymoma viral proto-oncogene 2 affects expression ISO Diclofenac affects the expression of AKT2 mRNA CTD PMID:24752500 NCBI chr 7:27,290,977...27,340,251
Ensembl chr 7:27,290,977...27,340,251
JBrowse link
G Alas1 aminolevulinic acid synthase 1 decreases expression EXP Diclofenac results in decreased expression of ALAS1 mRNA CTD PMID:26934552 NCBI chr 9:106,110,654...106,125,153
Ensembl chr 9:106,110,654...106,125,853
JBrowse link
G Alas2 aminolevulinic acid synthase 2, erythroid affects expression ISO Diclofenac affects the expression of ALAS2 mRNA CTD PMID:24752500 NCBI chr  X:149,330,443...149,353,614
Ensembl chr  X:149,330,371...149,353,634
JBrowse link
G Alb albumin affects binding
multiple interactions
decreases secretion
decreases expression
increases expression
ISO
EXP
Diclofenac binds to ALB protein
[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in decreased expression of ALB protein
Diclofenac results in decreased secretion of ALB protein
Diclofenac results in decreased expression of ALB protein
[Ranitidine co-treated with Diclofenac] results in decreased expression of ALB protein; Quercetin inhibits the reaction [[Ranitidine co-treated with Diclofenac] results in decreased expression of ALB protein]
Diclofenac results in increased expression of ALB mRNA
CTD PMID:9353694 PMID:19022234 PMID:28400101 PMID:36442613 PMID:38945390 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 increases expression
decreases expression
EXP Diclofenac results in increased expression of ALDH18A1 mRNA
Diclofenac results in decreased expression of ALDH18A1 mRNA
CTD PMID:26934552 PMID:35537566 NCBI chr19:40,538,701...40,576,907
Ensembl chr19:40,538,701...40,576,907
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 increases expression EXP Diclofenac results in increased expression of ALDH1B1 mRNA CTD PMID:26934552 NCBI chr 4:45,799,022...45,804,608
Ensembl chr 4:45,799,022...45,804,604
JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 decreases expression EXP Diclofenac results in decreased expression of ALDH1L2 mRNA CTD PMID:26934552 NCBI chr10:83,320,386...83,370,008
Ensembl chr10:83,323,314...83,370,004
JBrowse link
G Aldh3a2 aldehyde dehydrogenase family 3, subfamily A2 decreases expression EXP Diclofenac results in decreased expression of ALDH3A2 mRNA CTD PMID:26934552 NCBI chr11:61,114,240...61,158,267
Ensembl chr11:61,114,243...61,158,290
JBrowse link
G Aldoc aldolase C, fructose-bisphosphate increases expression ISO Diclofenac results in increased expression of ALDOC mRNA CTD PMID:30723492 NCBI chr11:78,213,899...78,218,607
Ensembl chr11:78,213,794...78,218,607
JBrowse link
G Alox15 arachidonate 15-lipoxygenase increases expression
multiple interactions
ISO
EXP
Diclofenac results in increased expression of ALOX15 mRNA
[Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in increased expression of ALOX15 mRNA
CTD PMID:23939143 PMID:37844793 NCBI chr11:70,234,973...70,279,465
Ensembl chr11:70,234,978...70,242,857
JBrowse link
G Amh anti-Mullerian hormone increases expression
multiple interactions
EXP Diclofenac results in increased expression of AMH mRNA
[Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of AMH mRNA
CTD PMID:35537566 PMID:37844793 NCBI chr10:80,641,074...80,643,513
Ensembl chr10:80,641,077...80,643,482
JBrowse link
G Amotl2 angiomotin-like 2 decreases expression EXP Diclofenac results in decreased expression of AMOTL2 mRNA CTD PMID:35537566 NCBI chr 9:102,594,290...102,610,616
Ensembl chr 9:102,593,871...102,610,617
JBrowse link
G Ang angiogenin, ribonuclease, RNase A family, 5 increases expression EXP Diclofenac results in increased expression of ANG mRNA CTD PMID:26934552 NCBI chr14:51,328,607...51,339,462
Ensembl chr14:51,328,607...51,339,466
JBrowse link
G Anxa8 annexin A8 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in increased expression of ANXA8 mRNA CTD PMID:37844793 NCBI chr14:33,807,936...33,822,528
Ensembl chr14:33,807,938...33,822,528
JBrowse link
G Aoc3 amine oxidase, copper containing 3 decreases expression EXP Diclofenac results in decreased expression of AOC3 mRNA CTD PMID:26934552 NCBI chr11:101,221,432...101,230,256
Ensembl chr11:101,221,431...101,232,764
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 affects expression ISO Diclofenac affects the expression of APAF1 mRNA CTD PMID:24752500 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632
JBrowse link
G Apcs amyloid P component, serum multiple interactions
increases expression
ISO
EXP
[Diclofenac co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of APCS protein
Diclofenac results in increased expression of APCS mRNA; Diclofenac results in increased expression of APCS protein
CTD PMID:25772430 PMID:26934552 NCBI chr 1:172,721,528...172,722,516
Ensembl chr 1:172,721,528...172,722,608
JBrowse link
G Apoa4 apolipoprotein A-IV affects expression EXP Diclofenac affects the expression of APOA4 mRNA CTD PMID:26934552 NCBI chr 9:46,152,142...46,154,756
Ensembl chr 9:46,151,994...46,154,757
JBrowse link
G Aqp2 aquaporin 2 decreases expression ISO Diclofenac results in decreased expression of AQP2 protein CTD PMID:15579502 NCBI chr15:99,476,937...99,482,426
Ensembl chr15:99,476,936...99,482,428
JBrowse link
G Aqp9 aquaporin 9 decreases expression EXP Diclofenac results in decreased expression of AQP9 mRNA CTD PMID:35537566 NCBI chr 9:71,017,941...71,075,170
Ensembl chr 9:71,017,941...71,075,964
JBrowse link
G Aqr aquarius affects expression ISO Diclofenac affects the expression of AQR mRNA CTD PMID:24752500 NCBI chr 2:113,931,642...114,005,788
Ensembl chr 2:113,931,651...114,017,505
JBrowse link
G Ar androgen receptor affects activity ISO Diclofenac affects the activity of AR protein CTD PMID:29777833 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821
JBrowse link
G Araf Araf proto-oncogene, serine/threonine kinase affects expression ISO Diclofenac affects the expression of ARAF mRNA CTD PMID:24752500 NCBI chr  X:20,663,946...20,726,760
Ensembl chr  X:20,664,053...20,726,758
JBrowse link
G Arhgap20 Rho GTPase activating protein 20 increases expression ISO Diclofenac results in increased expression of ARHGAP20 mRNA CTD PMID:30723492 NCBI chr 9:51,676,651...51,765,158
Ensembl chr 9:51,676,637...51,765,156
JBrowse link
G Arhgap26 Rho GTPase activating protein 26 affects expression ISO Diclofenac affects the expression of ARHGAP26 mRNA CTD PMID:24752500 NCBI chr18:38,734,531...39,509,338
Ensembl chr18:39,126,198...39,509,337
Ensembl chr18:39,126,198...39,509,337
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 affects expression ISO Diclofenac affects the expression of ARHGEF2 mRNA CTD PMID:24752500 NCBI chr 3:88,500,427...88,556,839
Ensembl chr 3:88,513,273...88,555,359
JBrowse link
G Arhgef3 Rho guanine nucleotide exchange factor 3 affects expression
decreases expression
ISO
EXP
Diclofenac affects the expression of ARHGEF3 mRNA
Diclofenac results in decreased expression of ARHGEF3 mRNA
CTD PMID:24752500 PMID:35537566 NCBI chr14:26,836,418...27,125,873
Ensembl chr14:26,836,856...27,125,868
JBrowse link
G Arhgef7 Rho guanine nucleotide exchange factor affects expression ISO Diclofenac affects the expression of ARHGEF7 mRNA CTD PMID:24752500 NCBI chr 8:11,778,053...11,885,219
Ensembl chr 8:11,777,721...11,885,219
JBrowse link
G Arid4a AT-rich interaction domain 4A multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in increased expression of ARID4A mRNA CTD PMID:37844793 NCBI chr12:71,061,314...71,146,125
Ensembl chr12:71,062,764...71,145,366
JBrowse link
G Arid5a AT-rich interaction domain 5A decreases expression EXP Diclofenac results in decreased expression of ARID5A mRNA CTD PMID:35537566 NCBI chr 1:36,346,814...36,363,117
Ensembl chr 1:36,346,814...36,363,110
JBrowse link
G Arid5b AT-rich interaction domain 5B decreases expression EXP Diclofenac results in decreased expression of ARID5B mRNA CTD PMID:26934552 NCBI chr10:67,928,353...68,114,596
Ensembl chr10:67,928,350...68,114,570
JBrowse link
G Arl11 ADP-ribosylation factor-like 11 decreases expression EXP Diclofenac results in decreased expression of ARL11 mRNA CTD PMID:35537566 NCBI chr14:61,543,740...61,549,386
Ensembl chr14:61,547,202...61,549,385
JBrowse link
G Armcx1 armadillo repeat containing, X-linked 1 increases expression ISO Diclofenac results in increased expression of ARMCX1 mRNA CTD PMID:30723492 NCBI chr  X:133,618,615...133,623,487
Ensembl chr  X:133,618,712...133,622,666
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator affects expression ISO Diclofenac affects the expression of ARNT mRNA CTD PMID:24752500 NCBI chr 3:95,341,674...95,404,551
Ensembl chr 3:95,341,699...95,404,551
JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in increased expression of ARRB1 mRNA CTD PMID:37844793 NCBI chr 7:99,184,356...99,255,979
Ensembl chr 7:99,184,673...99,255,978
JBrowse link
G Arrdc3 arrestin domain containing 3 increases expression EXP Diclofenac results in increased expression of ARRDC3 mRNA CTD PMID:35537566 NCBI chr13:81,031,508...81,044,161
Ensembl chr13:81,031,503...81,044,161
JBrowse link
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain1 affects expression ISO Diclofenac affects the expression of ASAP1 mRNA CTD PMID:24752500 NCBI chr15:63,958,704...64,254,922
Ensembl chr15:63,958,706...64,254,768
JBrowse link
G Ash2l ASH2 like histone lysine methyltransferase complex subunit affects expression ISO Diclofenac affects the expression of ASH2L mRNA CTD PMID:24752500 NCBI chr 8:26,306,028...26,337,722
Ensembl chr 8:26,306,024...26,337,722
JBrowse link
G Asic1 acid-sensing ion channel 1 decreases expression ISO Diclofenac results in decreased expression of ASIC1 mRNA CTD PMID:11588175 NCBI chr15:99,568,090...99,599,011
Ensembl chr15:99,568,249...99,599,011
JBrowse link
G Asic2 acid-sensing ion channel 2 decreases expression ISO Diclofenac results in decreased expression of ASIC2 mRNA CTD PMID:11588175 NCBI chr11:80,770,989...81,859,222
Ensembl chr11:80,770,995...81,859,283
JBrowse link
G Asic3 acid-sensing ion channel 3 decreases expression
decreases activity
ISO Diclofenac results in decreased expression of ASIC3 mRNA
Diclofenac results in decreased activity of ASIC3 protein
CTD PMID:11588175 NCBI chr 5:24,618,449...24,622,836
Ensembl chr 5:24,618,390...24,622,833
JBrowse link
G Asl argininosuccinate lyase affects expression ISO Diclofenac affects the expression of ASL mRNA CTD PMID:24752500 NCBI chr 5:130,040,099...130,053,222
Ensembl chr 5:130,040,099...130,058,088
JBrowse link
G Asns asparagine synthetase decreases expression
increases expression
ISO
EXP
Diclofenac results in decreased expression of ASNS mRNA
Diclofenac results in increased expression of ASNS mRNA
CTD PMID:19192274 PMID:26934552 PMID:35537566 NCBI chr 6:7,675,169...7,693,209
Ensembl chr 6:7,675,169...7,693,254
JBrowse link
G Ass1 argininosuccinate synthetase 1 decreases expression EXP Diclofenac results in decreased expression of ASS1 mRNA CTD PMID:26934552 NCBI chr 2:31,360,282...31,410,682
Ensembl chr 2:31,360,219...31,410,684
JBrowse link
G Atf2 activating transcription factor 2 affects expression ISO Diclofenac affects the expression of ATF2 mRNA CTD PMID:24752500 NCBI chr 2:73,646,853...73,723,094
Ensembl chr 2:73,646,853...73,722,983
JBrowse link
G Atf4 activating transcription factor 4 affects expression
decreases expression
increases expression
ISO
EXP
Diclofenac affects the expression of ATF4 mRNA
Diclofenac results in decreased expression of ATF4 mRNA
Diclofenac results in increased expression of ATF4 mRNA
CTD PMID:24752500 PMID:27313093 PMID:35537566 NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742
JBrowse link
G Atf5 activating transcription factor 5 decreases expression EXP Diclofenac results in decreased expression of ATF5 mRNA CTD PMID:35537566 NCBI chr 7:44,461,680...44,466,082
Ensembl chr 7:44,461,680...44,466,082
JBrowse link
G Atp11a ATPase, class VI, type 11A increases expression EXP Diclofenac results in increased expression of ATP11A mRNA CTD PMID:26934552 NCBI chr 8:12,807,016...12,918,728
Ensembl chr 8:12,807,014...12,918,728
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha multiple interactions
increases expression
ISO [Diclofenac co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ATP5F1A protein
Diclofenac results in increased expression of ATP5F1A protein
CTD PMID:25772430 NCBI chr18:77,861,468...77,870,569
Ensembl chr18:77,861,429...77,870,569
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta multiple interactions
increases expression
ISO [Diclofenac co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ATP5F1B protein
Diclofenac results in increased expression of ATP5F1B protein
CTD PMID:25772430 NCBI chr10:127,919,176...127,926,257
Ensembl chr10:127,919,142...127,926,260
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 multiple interactions
increases expression
ISO [Diclofenac co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ATP5PF protein
Diclofenac results in increased expression of ATP5PF protein
CTD PMID:25772430 NCBI chr16:84,624,754...84,632,495
Ensembl chr16:84,624,754...84,632,513
JBrowse link
G Aurkaip1 aurora kinase A interacting protein 1 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of AURKAIP1 mRNA CTD PMID:37844793 NCBI chr 4:155,915,709...155,917,555
Ensembl chr 4:155,915,729...155,917,587
JBrowse link
G Azin1 antizyme inhibitor 1 affects expression ISO Diclofenac affects the expression of AZIN1 mRNA CTD PMID:24752500 NCBI chr15:38,487,674...38,523,506
Ensembl chr15:38,487,671...38,519,510
JBrowse link
G B3galt1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 increases expression EXP Diclofenac results in increased expression of B3GALT1 mRNA CTD PMID:26934552 NCBI chr 2:67,395,528...67,953,226
Ensembl chr 2:67,396,215...67,953,033
JBrowse link
G Bach1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 affects expression ISO Diclofenac affects the expression of BACH1 mRNA CTD PMID:24752500 NCBI chr16:87,495,842...87,530,234
Ensembl chr16:87,495,833...87,530,234
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases activity ISO Diclofenac results in increased activity of BAK1 protein CTD PMID:18191430 NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
JBrowse link
G Bard1 BRCA1 associated RING domain 1 affects expression ISO Diclofenac affects the expression of BARD1 mRNA CTD PMID:24752500 NCBI chr 1:71,066,694...71,142,300
Ensembl chr 1:71,066,657...71,142,305
JBrowse link
G Bax BCL2-associated X protein increases activity
increases expression
affects localization
ISO Diclofenac results in increased activity of BAX protein
Diclofenac results in increased expression of BAX mRNA
Diclofenac affects the localization of BAX protein
CTD PMID:18191430 PMID:29027214 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcar3 breast cancer anti-estrogen resistance 3 decreases expression EXP Diclofenac results in decreased expression of BCAR3 mRNA CTD PMID:35537566 NCBI chr 3:122,213,406...122,323,840
Ensembl chr 3:122,087,785...122,323,840
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 increases expression ISO Diclofenac results in increased expression of BCL2 mRNA CTD PMID:29027214 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2a1b B cell leukemia/lymphoma 2 related protein A1b decreases expression ISO Diclofenac results in decreased expression of BCL2A1 mRNA CTD PMID:19192274 NCBI chr 9:89,081,326...89,089,891
Ensembl chr 9:89,081,262...89,089,880
JBrowse link
G Bcl2l1 BCL2-like 1 increases expression
affects expression
ISO Diclofenac results in increased expression of BCL2L1 mRNA alternative form
Diclofenac affects the expression of BCL2L1 mRNA
CTD PMID:14609740 PMID:24752500 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Bcl2l11 BCL2 like 11 affects expression ISO Diclofenac affects the expression of BCL2L11 mRNA CTD PMID:24752500 NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467
JBrowse link
G Bcl3 B cell leukemia/lymphoma 3 increases expression EXP Diclofenac results in increased expression of BCL3 mRNA CTD PMID:26934552 NCBI chr 7:19,542,387...19,556,691
Ensembl chr 7:19,542,387...19,556,695
JBrowse link
G Bcl6 B cell leukemia/lymphoma 6 decreases expression EXP Diclofenac results in decreased expression of BCL6 mRNA CTD PMID:26934552 NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602
JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase, type 1 decreases expression EXP Diclofenac results in decreased expression of BDH1 mRNA CTD PMID:26934552 NCBI chr16:31,241,115...31,277,719
Ensembl chr16:31,241,098...31,277,719
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
affects expression
increases activity
ISO 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Diclofenac results in increased activity of BID protein]
Diclofenac affects the expression of BID mRNA
CTD PMID:18191430 PMID:24752500 NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814
JBrowse link
G Bmp4 bone morphogenetic protein 4 affects expression ISO Diclofenac affects the expression of BMP4 mRNA CTD PMID:24752500 NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126
JBrowse link
G Bmp6 bone morphogenetic protein 6 decreases expression
increases expression
EXP
ISO
Diclofenac results in decreased expression of BMP6 mRNA
Diclofenac results in increased expression of BMP6 mRNA
CTD PMID:26934552 PMID:32816093 NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278
JBrowse link
G Braf Braf transforming gene affects expression ISO Diclofenac affects the expression of BRAF mRNA CTD PMID:24752500 NCBI chr 6:39,580,171...39,702,592
Ensembl chr 6:39,580,171...39,702,397
JBrowse link
G Brca1 breast cancer 1, early onset increases expression EXP Diclofenac results in increased expression of BRCA1 mRNA CTD PMID:26934552 NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781
JBrowse link
G Brca2 breast cancer 2, early onset multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in increased expression of BRCA2 mRNA CTD PMID:37844793 NCBI chr 5:150,445,759...150,493,612
Ensembl chr 5:150,446,095...150,493,794
JBrowse link
G Brd3os bromodomain containing 3, opposite strand decreases expression EXP Diclofenac results in decreased expression of BRD3OS mRNA CTD PMID:35537566 NCBI chr 2:27,332,486...27,334,233
Ensembl chr 2:27,332,336...27,334,233
JBrowse link
G Brdt bromodomain, testis-specific decreases expression EXP Diclofenac results in decreased expression of BRDT mRNA CTD PMID:35537566 NCBI chr 5:107,478,982...107,534,927
Ensembl chr 5:107,479,025...107,534,924
JBrowse link
G Brip1 BRCA1 interacting protein C-terminal helicase 1 affects expression ISO Diclofenac affects the expression of BRIP1 mRNA CTD PMID:24752500 NCBI chr11:85,948,957...86,092,041
Ensembl chr11:85,948,964...86,092,019
JBrowse link
G Btg1 BTG anti-proliferation factor 1 decreases expression EXP Diclofenac results in decreased expression of BTG1 mRNA CTD PMID:26934552 NCBI chr10:96,452,863...96,458,675
Ensembl chr10:96,452,868...96,458,671
JBrowse link
G C1qa complement component 1, q subcomponent, alpha polypeptide increases expression EXP Diclofenac results in increased expression of C1QA mRNA CTD PMID:26934552 NCBI chr 4:136,623,227...136,626,155
Ensembl chr 4:136,623,228...136,626,114
JBrowse link
G C1qb complement component 1, q subcomponent, beta polypeptide increases expression EXP Diclofenac results in increased expression of C1QB mRNA CTD PMID:26934552 NCBI chr 4:136,607,437...136,613,511
Ensembl chr 4:136,607,440...136,613,498
JBrowse link
G C1qc complement component 1, q subcomponent, C chain increases expression EXP Diclofenac results in increased expression of C1QC mRNA CTD PMID:26934552 NCBI chr 4:136,617,115...136,620,225
Ensembl chr 4:136,617,115...136,620,376
JBrowse link
G C2 complement C2 increases expression EXP Diclofenac results in increased expression of C2 mRNA CTD PMID:26934552 NCBI chr17:35,081,578...35,101,076
Ensembl chr17:35,081,580...35,117,241
JBrowse link
G C4b complement C4B (Chido blood group) increases expression EXP Diclofenac results in increased expression of C4B mRNA CTD PMID:26934552 NCBI chr17:34,947,249...34,962,876
Ensembl chr17:34,947,354...34,962,856
JBrowse link
G C4bp complement component 4 binding protein increases expression EXP Diclofenac results in increased expression of C4BP mRNA CTD PMID:26934552 NCBI chr 1:130,562,510...130,589,365
Ensembl chr 1:130,562,510...130,589,369
JBrowse link
G Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit decreases expression EXP Diclofenac results in decreased expression of CACNA1B mRNA CTD PMID:26934552 NCBI chr 2:24,493,872...24,653,210
Ensembl chr 2:24,493,899...24,653,164
JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha decreases expression ISO Diclofenac results in decreased expression of CALCA mRNA CTD PMID:11588175 NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592
JBrowse link
G Calm1 calmodulin 1 affects expression ISO Diclofenac affects the expression of CALM1 mRNA CTD PMID:24752500 NCBI chr12:100,165,694...100,176,083
Ensembl chr12:100,165,694...100,176,073
JBrowse link
G Calml3 calmodulin-like 3 increases expression ISO Diclofenac results in increased expression of CALML3 mRNA CTD PMID:30723492 NCBI chr13:3,852,893...3,854,318
Ensembl chr13:3,852,896...3,854,316
JBrowse link
G Calr calreticulin affects expression
decreases expression
ISO Diclofenac affects the expression of CALR mRNA
Diclofenac results in decreased expression of CALR mRNA
CTD PMID:18246545 NCBI chr 8:85,568,717...85,573,560
Ensembl chr 8:85,568,479...85,573,563
JBrowse link
G Camk1d calcium/calmodulin-dependent protein kinase ID increases expression EXP Diclofenac results in increased expression of CAMK1D mRNA CTD PMID:26934552 NCBI chr 2:5,298,268...5,719,665
Ensembl chr 2:5,298,268...5,719,326
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II, beta increases expression ISO Diclofenac results in increased expression of CAMK2B mRNA CTD PMID:30723492 NCBI chr11:5,919,642...6,016,401
Ensembl chr11:5,919,644...6,016,362
JBrowse link
G Camp cathelicidin antimicrobial peptide increases expression EXP Diclofenac results in increased expression of CAMP mRNA CTD PMID:26934552 NCBI chr 9:109,676,445...109,678,524
Ensembl chr 9:109,676,447...109,678,685
JBrowse link
G Capn10 calpain 10 affects expression ISO Diclofenac affects the expression of CAPN10 mRNA CTD PMID:24752500 NCBI chr 1:92,862,130...92,875,670
Ensembl chr 1:92,862,098...92,875,663
JBrowse link
G Car1 carbonic anhydrase 1 decreases expression EXP Diclofenac results in decreased expression of CAR1 mRNA CTD PMID:26934552 NCBI chr 3:14,831,274...14,873,425
Ensembl chr 3:14,831,276...14,873,428
JBrowse link
G Car13 carbonic anhydrase 13 decreases expression EXP Diclofenac results in decreased expression of CAR13 mRNA CTD PMID:26934552 NCBI chr 3:14,706,787...14,728,062
Ensembl chr 3:14,706,787...14,728,062
JBrowse link
G Car3 carbonic anhydrase 3 decreases expression
increases secretion
EXP
ISO
Diclofenac results in decreased expression of CAR3 mRNA
Diclofenac results in increased secretion of CAR3 protein
CTD PMID:24038040 PMID:26934552 NCBI chr 3:14,928,598...14,937,441
Ensembl chr 3:14,928,572...14,937,583
JBrowse link
G Cars1 cysteinyl-tRNA synthetase 1 decreases expression EXP Diclofenac results in decreased expression of CARS1 mRNA CTD PMID:35537566 NCBI chr 7:143,110,967...143,153,827
Ensembl chr 7:143,110,967...143,153,827
JBrowse link
G Casp1 caspase 1 multiple interactions
increases cleavage
ISO diacerein inhibits the reaction [Diclofenac results in increased cleavage of CASP1 protein]; Diclofenac inhibits the reaction [Freund's Adjuvant results in increased cleavage of CASP1 protein] CTD PMID:25450234 PMID:38582345 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Casp2 caspase 2 multiple interactions
affects expression
ISO Diclofenac inhibits the reaction [Thapsigargin results in increased activity of CASP2 protein]; Diclofenac inhibits the reaction [Tunicamycin results in increased activity of CASP2 protein]
Diclofenac affects the expression of CASP2 mRNA
CTD PMID:16388830 PMID:24752500 NCBI chr 6:42,241,942...42,259,442
Ensembl chr 6:42,241,919...42,259,442
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
EXP
ISO
Diclofenac results in increased activity of CASP3 protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[TNF protein co-treated with IFNG protein] promotes the reaction [Diclofenac results in increased activity of CASP3 protein]]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Diclofenac results in increased activity of CASP3 protein]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [IFNG protein promotes the reaction [Diclofenac results in increased activity of CASP3 protein]]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [TNF protein promotes the reaction [Diclofenac results in increased activity of CASP3 protein]]; 2-aminoethoxydiphenyl borate inhibits the reaction [[TNF protein co-treated with IFNG protein] promotes the reaction [Diclofenac results in increased activity of CASP3 protein]]; 2-aminoethoxydiphenyl borate inhibits the reaction [TNF protein promotes the reaction [Diclofenac results in increased activity of CASP3 protein]]; [TNF protein co-treated with IFNG protein] promotes the reaction [Diclofenac results in increased activity of CASP3 protein]; Diclofenac inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]; Diclofenac inhibits the reaction [Tunicamycin results in increased activity of CASP3 protein]; IFNG protein promotes the reaction [Diclofenac results in increased activity of CASP3 protein]; TNF protein promotes the reaction [Diclofenac results in increased activity of CASP3 protein]
2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone inhibits the reaction [Diclofenac results in increased activity of CASP3 protein]; [Water deficiency co-treated with Diclofenac] results in increased expression of CASP3 protein; alpha-Tocopherol inhibits the reaction [Diclofenac results in increased activity of CASP3 protein]; Cyclosporine inhibits the reaction [Diclofenac results in increased activity of CASP3 protein]; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in increased expression of CASP3 protein]; Thiourea analog inhibits the reaction [Diclofenac results in increased activity of CASP3 protein]
CTD PMID:12826271 PMID:14599462 PMID:14609740 PMID:16388830 PMID:24770551 More... NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp6 caspase 6 affects expression ISO Diclofenac affects the expression of CASP6 mRNA CTD PMID:24752500 NCBI chr 3:129,695,064...129,707,761
Ensembl chr 3:129,695,074...129,707,752
JBrowse link
G Casp8 caspase 8 increases activity
affects expression
multiple interactions
ISO Diclofenac results in increased activity of CASP8 protein
Diclofenac affects the expression of CASP8 mRNA
[Diclofenac co-treated with Hyaluronic Acid] results in increased activity of CASP8 protein; [TNF protein co-treated with Diclofenac] results in increased activity of CASP8 protein; Acetylcysteine inhibits the reaction [[TNF protein co-treated with Diclofenac] results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [Diclofenac results in increased activity of CASP8 protein]; benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [[TNF protein co-treated with Diclofenac] results in increased activity of CASP8 protein]; benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [Diclofenac results in increased activity of CASP8 protein]
CTD PMID:14609740 PMID:20237495 PMID:24752500 PMID:27313093 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
increases activity
ISO [TNF protein co-treated with Diclofenac] results in increased activity of CASP9 protein; Acetylcysteine inhibits the reaction [[TNF protein co-treated with Diclofenac] results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Diclofenac results in increased activity of CASP9 protein]; benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [[TNF protein co-treated with Diclofenac] results in increased activity of CASP9 protein]; benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [Diclofenac results in increased activity of CASP9 protein]; Diclofenac inhibits the reaction [Thapsigargin results in increased activity of CASP9 protein]; Diclofenac inhibits the reaction [Tunicamycin results in increased activity of CASP9 protein]
Diclofenac results in increased expression of CASP9 mRNA
CTD PMID:14609740 PMID:16388830 PMID:25014874 PMID:27313093 PMID:29027214 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Cat catalase increases activity
decreases activity
multiple interactions
ISO
EXP
Diclofenac results in increased activity of CAT protein
Diclofenac results in decreased activity of CAT protein
Ondansetron promotes the reaction [Diclofenac results in decreased activity of CAT protein]
[Water deficiency co-treated with Diclofenac] results in decreased activity of CAT protein; Acetylcysteine inhibits the reaction [Diclofenac results in decreased activity of CAT protein]; Diclofenac inhibits the reaction [Freund's Adjuvant results in decreased activity of CAT protein]; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in decreased activity of CAT protein]; Silymarin inhibits the reaction [Diclofenac results in decreased activity of CAT protein]
CTD PMID:17274466 PMID:23994749 PMID:28535741 PMID:31042592 PMID:31332906 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cbl Casitas B-lineage lymphoma affects expression ISO Diclofenac affects the expression of CBL mRNA CTD PMID:24752500 NCBI chr 9:44,054,273...44,145,556
Ensembl chr 9:44,054,273...44,145,346
JBrowse link
G Cbr1 carbonyl reductase 1 affects expression ISO Diclofenac affects the expression of CBR1 mRNA CTD PMID:24752500 NCBI chr16:93,404,752...93,407,226
Ensembl chr16:93,402,741...93,407,393
JBrowse link
G Cbs cystathionine beta-synthase affects expression ISO Diclofenac affects the expression of CBS mRNA CTD PMID:24752500 NCBI chr17:31,831,602...31,856,170
Ensembl chr17:31,827,868...31,856,212
JBrowse link
G Ccdc137 coiled-coil domain containing 137 increases expression EXP Diclofenac results in increased expression of CCDC137 mRNA CTD PMID:35537566 NCBI chr11:120,348,947...120,355,184
Ensembl chr11:120,348,941...120,355,184
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
increases secretion
multiple interactions
affects expression
EXP
ISO
Diclofenac results in increased expression of CCL2 mRNA
Diclofenac analog results in increased secretion of CCL2 protein
SB 203580 inhibits the reaction [Diclofenac analog results in increased expression of CCL2 mRNA]; U 0126 inhibits the reaction [Diclofenac analog results in increased expression of CCL2 mRNA]
Diclofenac results in increased expression of CCL2 protein
Diclofenac affects the expression of CCL2 mRNA
[Water deficiency co-treated with Diclofenac] results in increased expression of CCL2 protein; Diclofenac promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL2 mRNA]; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in increased expression of CCL2 protein]
CTD PMID:22285467 PMID:23939143 PMID:24104198 PMID:25051504 PMID:27671914 More... NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
decreases expression
ISO
EXP
Diclofenac promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL3 mRNA]
Diclofenac results in decreased expression of CCL3 mRNA
CTD PMID:23939143 PMID:35537566 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
JBrowse link
G Ccl6 C-C motif chemokine ligand 6 increases expression EXP Diclofenac results in increased expression of CCL6 mRNA CTD PMID:26934552 NCBI chr11:83,478,712...83,483,913
Ensembl chr11:83,478,708...83,483,913
JBrowse link
G Ccl9 C-C motif chemokine ligand 9 increases expression EXP Diclofenac results in increased expression of CCL9 mRNA CTD PMID:26934552 NCBI chr11:83,463,743...83,469,462
Ensembl chr11:83,463,745...83,469,462
JBrowse link
G Ccn1 cellular communication network factor 1 affects expression
increases expression
ISO Diclofenac affects the expression of CCN1 mRNA
Diclofenac results in increased expression of CCN1 mRNA
CTD PMID:19192274 PMID:24752500 NCBI chr 3:145,352,726...145,355,740
Ensembl chr 3:145,352,731...145,355,736
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
affects expression
decreases expression
increases expression
ISO
EXP
Diclofenac inhibits the reaction [TNF protein results in increased expression of CCND1 protein]
Diclofenac affects the expression of CCND1 mRNA
Diclofenac results in decreased expression of CCND1 mRNA
Diclofenac results in increased expression of CCND1 mRNA
Diclofenac results in decreased expression of CCND1 protein
CTD PMID:15188006 PMID:15489888 PMID:19022234 PMID:26934552 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Ccnd3 cyclin D3 affects expression ISO Diclofenac affects the expression of CCND3 mRNA CTD PMID:24752500 NCBI chr17:47,815,976...47,910,614
Ensembl chr17:47,815,976...47,910,616
JBrowse link
G Ccne1 cyclin E1 affects expression ISO Diclofenac affects the expression of CCNE1 mRNA CTD PMID:24752500 NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959
JBrowse link
G Ccne2 cyclin E2 affects expression ISO Diclofenac affects the expression of CCNE2 mRNA CTD PMID:24752500 NCBI chr 4:11,190,489...11,204,781
Ensembl chr 4:11,191,351...11,204,779
JBrowse link
G Ccnf cyclin F affects expression ISO Diclofenac affects the expression of CCNF mRNA CTD PMID:24752500 NCBI chr17:24,441,518...24,470,333
Ensembl chr17:24,441,172...24,470,458
JBrowse link
G Ccng1 cyclin G1 increases expression ISO Diclofenac results in increased expression of CCNG1 mRNA CTD PMID:19022234 NCBI chr11:40,639,379...40,646,044
Ensembl chr11:40,639,379...40,646,138
JBrowse link
G Ccnh cyclin H affects expression ISO Diclofenac affects the expression of CCNH mRNA CTD PMID:24752500 NCBI chr13:85,337,504...85,361,850
Ensembl chr13:85,337,527...85,371,588
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 increases expression EXP Diclofenac results in increased expression of CCR1 mRNA CTD PMID:26934552 NCBI chr 9:123,762,163...123,768,729
Ensembl chr 9:123,762,161...123,768,729
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 increases expression EXP Diclofenac results in increased expression of CCR5 mRNA CTD PMID:26934552 NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736
JBrowse link
G Cd14 CD14 antigen increases expression EXP Diclofenac results in increased expression of CD14 mRNA CTD PMID:26934552 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851
JBrowse link
G Cd163 CD163 antigen increases expression EXP Diclofenac results in increased expression of CD163 mRNA CTD PMID:26934552 NCBI chr 6:124,281,596...124,307,488
Ensembl chr 6:124,281,615...124,307,486
JBrowse link
G Cd200r4 CD200 receptor 4 decreases expression EXP Diclofenac results in decreased expression of CD200R4 mRNA CTD PMID:35537566 NCBI chr16:44,632,036...44,659,497
Ensembl chr16:44,632,096...44,659,513
JBrowse link
G Cd244a CD244 molecule A decreases expression EXP Diclofenac results in decreased expression of CD244 mRNA CTD PMID:35537566 NCBI chr 1:171,386,761...171,412,884
Ensembl chr 1:171,386,761...171,437,314
JBrowse link
G Cd28 CD28 antigen increases expression EXP Diclofenac results in increased expression of CD28 mRNA CTD PMID:26934552 NCBI chr 1:60,785,547...60,812,521
Ensembl chr 1:60,755,959...60,812,518
JBrowse link
G Cd44 CD44 antigen increases expression EXP Diclofenac results in increased expression of CD44 mRNA CTD PMID:26934552 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
JBrowse link
G Cd55 CD55 molecule, decay accelerating factor for complement increases expression EXP Diclofenac results in increased expression of CD55 mRNA CTD PMID:26934552 NCBI chr 1:130,357,526...130,390,513
Ensembl chr 1:130,366,764...130,390,481
JBrowse link
G Cd5l CD5 antigen-like increases expression EXP Diclofenac results in increased expression of CD5L mRNA CTD PMID:26934552 NCBI chr 3:87,265,188...87,278,381
Ensembl chr 3:87,265,188...87,278,380
JBrowse link
G Cd9 CD9 antigen increases expression EXP Diclofenac results in increased expression of CD9 mRNA CTD PMID:26934552 NCBI chr 6:125,437,229...125,471,723
Ensembl chr 6:125,437,229...125,471,754
JBrowse link
G Cdc42ep5 CDC42 effector protein 5 decreases expression EXP Diclofenac results in decreased expression of CDC42EP5 mRNA CTD PMID:26934552 NCBI chr 7:4,154,259...4,167,830
Ensembl chr 7:4,154,259...4,167,859
JBrowse link
G Cdc6 cell division cycle 6 affects expression ISO Diclofenac affects the expression of CDC6 mRNA CTD PMID:24752500 NCBI chr11:98,798,627...98,814,768
Ensembl chr11:98,798,627...98,814,766
JBrowse link
G Cdc7 cell division cycle 7 affects expression ISO Diclofenac affects the expression of CDC7 mRNA CTD PMID:24752500 NCBI chr 5:107,112,201...107,132,298
Ensembl chr 5:107,112,188...107,132,298
JBrowse link
G Cdca5 cell division cycle associated 5 increases expression EXP Diclofenac results in increased expression of CDCA5 mRNA CTD PMID:26934552 NCBI chr19:6,135,127...6,141,803
Ensembl chr19:6,135,013...6,141,807
JBrowse link
G Cdh1 cadherin 1 increases expression
affects expression
decreases expression
ISO Diclofenac results in increased expression of CDH1 protein
Diclofenac affects the expression of CDH1 mRNA
Diclofenac results in decreased expression of CDH1 mRNA
CTD PMID:19022234 PMID:19628293 PMID:24752500 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
JBrowse link
G Cdk2 cyclin dependent kinase 2 affects expression ISO Diclofenac affects the expression of CDK2 mRNA CTD PMID:24752500 NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900
JBrowse link
G Cdk5 cyclin dependent kinase 5 affects expression ISO Diclofenac affects the expression of CDK5 mRNA CTD PMID:24752500 NCBI chr 5:24,612,595...24,628,737
Ensembl chr 5:24,623,239...24,628,528
JBrowse link
G Cdk5r1 cyclin dependent kinase 5, regulatory subunit 1 increases expression ISO Diclofenac results in increased expression of CDK5R1 mRNA CTD PMID:30723492 NCBI chr11:80,367,849...80,372,010
Ensembl chr11:80,367,849...80,372,010
JBrowse link
G Cdk6 cyclin dependent kinase 6 affects expression ISO Diclofenac affects the expression of CDK6 mRNA CTD PMID:24752500 NCBI chr 5:3,391,004...3,581,008
Ensembl chr 5:3,391,485...3,581,008
JBrowse link
G Cdk7 cyclin dependent kinase 7 affects expression ISO Diclofenac affects the expression of CDK7 mRNA CTD PMID:24752500 NCBI chr13:100,833,532...100,867,454
Ensembl chr13:100,839,139...100,867,447
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A increases expression ISO
EXP
Diclofenac results in increased expression of CDKN1A mRNA CTD PMID:19022234 PMID:26934552 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B affects expression ISO Diclofenac affects the expression of CDKN1B mRNA CTD PMID:24752500 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476
JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 affects expression ISO Diclofenac affects the expression of CDT1 mRNA CTD PMID:24752500 NCBI chr 8:123,294,754...123,299,869
Ensembl chr 8:123,294,754...123,300,293
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression
affects expression
ISO Diclofenac results in increased expression of CEBPB mRNA
Diclofenac affects the expression of CEBPB mRNA
CTD PMID:19022234 PMID:24752500 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338
JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma decreases expression EXP Diclofenac results in decreased expression of CEBPG mRNA CTD PMID:35537566 NCBI chr 7:34,745,847...34,755,991
Ensembl chr 7:34,745,847...34,755,998
JBrowse link
G Cep162 centrosomal protein 162 decreases expression EXP Diclofenac results in decreased expression of CEP162 mRNA CTD PMID:35537566 NCBI chr 9:87,071,626...87,137,589
Ensembl chr 9:87,071,630...87,137,589
JBrowse link
G Cers6 ceramide synthase 6 increases expression EXP Diclofenac results in increased expression of CERS6 mRNA CTD PMID:26934552 NCBI chr 2:68,691,489...68,944,628
Ensembl chr 2:68,691,785...68,944,626
JBrowse link
G Ces1d carboxylesterase 1D decreases expression EXP Diclofenac results in decreased expression of CES1D mRNA CTD PMID:26934552 NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466
JBrowse link
G Ces1e carboxylesterase 1E decreases expression EXP Diclofenac results in decreased expression of CES1E mRNA CTD PMID:26934552 NCBI chr 8:93,927,846...93,956,233
Ensembl chr 8:93,927,846...93,956,247
JBrowse link
G Cfap97d1 CFAP97 domain containing 1 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of CFAP97D1 mRNA CTD PMID:37844793 NCBI chr11:101,877,882...101,883,090
Ensembl chr11:101,875,105...101,883,090
JBrowse link
G Cfh complement component factor h increases expression EXP Diclofenac results in increased expression of CFH mRNA CTD PMID:26934552 NCBI chr 1:140,013,593...140,111,149
Ensembl chr 1:140,012,446...140,111,502
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator multiple interactions
affects expression
ISO [Diclofenac co-treated with Hyaluronic Acid] results in decreased expression of CFLAR protein
Diclofenac affects the expression of CFLAR mRNA
CTD PMID:20237495 PMID:24752500 NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 decreases expression EXP Diclofenac results in decreased expression of CGREF1 mRNA CTD PMID:26934552 NCBI chr 5:31,090,487...31,102,771
Ensembl chr 5:31,090,487...31,102,935
JBrowse link
G Chac1 ChaC, cation transport regulator 1 increases expression
decreases expression
EXP Diclofenac results in increased expression of CHAC1 mRNA
Diclofenac results in decreased expression of CHAC1 mRNA
CTD PMID:26934552 PMID:35537566 NCBI chr 2:119,181,723...119,184,807
Ensembl chr 2:119,181,710...119,184,862
JBrowse link
G Chchd1 coiled-coil-helix-coiled-coil-helix domain containing 1 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of CHCHD1 mRNA CTD PMID:37844793 NCBI chr14:20,753,095...20,754,493
Ensembl chr14:20,753,074...20,754,493
JBrowse link
G Chdh choline dehydrogenase affects expression ISO Diclofenac affects the expression of CHDH mRNA CTD PMID:24752500 NCBI chr14:29,730,957...29,762,423
Ensembl chr14:29,730,980...29,762,484
JBrowse link
G Chek1 checkpoint kinase 1 affects expression ISO Diclofenac affects the expression of CHEK1 mRNA CTD PMID:24752500 NCBI chr 9:36,619,935...36,637,897
Ensembl chr 9:36,619,778...36,638,361
JBrowse link
G Chil3 chitinase-like 3 increases expression EXP Diclofenac results in increased expression of CHIL3 mRNA CTD PMID:26934552 NCBI chr 3:106,054,870...106,074,852
Ensembl chr 3:106,054,870...106,074,880
JBrowse link
G Chil4 chitinase-like 4 increases expression EXP Diclofenac results in increased expression of CHI3L4 mRNA CTD PMID:26934552 NCBI chr 3:106,108,807...106,126,795
Ensembl chr 3:106,108,806...106,126,823
JBrowse link
G Chka choline kinase alpha affects expression ISO Diclofenac affects the expression of CHKA mRNA CTD PMID:24752500 NCBI chr19:3,901,585...3,944,368
Ensembl chr19:3,901,773...3,944,369
JBrowse link
G Chkb choline kinase beta affects expression ISO Diclofenac affects the expression of CHKB mRNA CTD PMID:24752500 NCBI chr15:89,310,552...89,314,130
Ensembl chr15:89,310,563...89,314,111
JBrowse link
G Chl1 cell adhesion molecule L1-like increases expression EXP Diclofenac results in increased expression of CHL1 mRNA CTD PMID:26934552 NCBI chr 6:103,487,372...103,709,999
Ensembl chr 6:103,487,547...103,727,172
JBrowse link
G Chst4 carbohydrate sulfotransferase 4 decreases expression EXP Diclofenac results in decreased expression of CHST4 mRNA CTD PMID:26934552 NCBI chr 8:110,755,776...110,766,033
Ensembl chr 8:110,755,785...110,766,372
JBrowse link
G Chuk conserved helix-loop-helix ubiquitous kinase multiple interactions ISO Diclofenac inhibits the reaction [TNF protein results in increased activity of CHUK protein]
Diclofenac inhibits the reaction [Freund's Adjuvant results in increased phosphorylation of CHUK protein]
CTD PMID:15489888 PMID:25935278 NCBI chr19:44,061,773...44,095,940
Ensembl chr19:44,061,774...44,095,919
JBrowse link
G Cib1 calcium and integrin binding 1 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of CIB1 mRNA CTD PMID:37844793 NCBI chr 7:79,876,904...79,882,367
Ensembl chr 7:79,876,895...79,882,561
JBrowse link
G Clec2h C-type lectin domain family 2, member h decreases expression EXP Diclofenac results in decreased expression of CLEC2H mRNA CTD PMID:26934552 NCBI chr 6:128,639,348...128,654,337
Ensembl chr 6:128,639,348...128,654,337
JBrowse link
G Clec4n C-type lectin domain family 4, member n increases expression EXP Diclofenac results in increased expression of CLEC4N mRNA CTD PMID:26934552 NCBI chr 6:123,206,802...123,223,983
Ensembl chr 6:123,206,802...123,223,980
JBrowse link
G Clu clusterin increases expression
multiple interactions
EXP
ISO
Diclofenac results in increased expression of CLU protein
[Diclofenac co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CLU protein
CTD PMID:23506792 PMID:25772430 NCBI chr14:66,206,093...66,218,992
Ensembl chr14:66,205,932...66,218,996
JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 affects expression ISO Diclofenac affects the expression of CMPK2 mRNA CTD PMID:24752500 NCBI chr12:26,519,121...26,529,836
Ensembl chr12:26,519,203...26,529,836
JBrowse link
G Col3a1 collagen, type III, alpha 1 decreases expression
multiple interactions
EXP
ISO
Diclofenac results in decreased expression of COL3A1 mRNA
[Water deficiency co-treated with Diclofenac] results in increased expression of COL3A1 protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in increased expression of COL3A1 protein]
CTD PMID:26934552 PMID:31042592 NCBI chr 1:45,350,698...45,388,866
Ensembl chr 1:45,350,698...45,388,866
JBrowse link
G Coq8a coenzyme Q8A decreases expression EXP Diclofenac results in decreased expression of ADCK3 mRNA CTD PMID:26934552 NCBI chr 1:179,992,803...180,023,585
Ensembl chr 1:179,992,803...180,027,167
JBrowse link
G Cotl1 coactosin like F-actin binding protein 1 increases expression EXP Diclofenac results in increased expression of COTL1 mRNA CTD PMID:26934552 NCBI chr 8:120,535,953...120,567,318
Ensembl chr 8:120,535,961...120,567,283
JBrowse link
G Cox4i2 cytochrome c oxidase subunit 4I2 increases expression EXP Diclofenac results in increased expression of COX4I2 mRNA CTD PMID:35537566 NCBI chr 2:152,596,093...152,606,957
Ensembl chr 2:152,596,093...152,606,957
JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 decreases expression EXP Diclofenac results in decreased expression of COX6A2 mRNA CTD PMID:35537566 NCBI chr 7:127,804,607...127,805,538
Ensembl chr 7:127,804,607...127,805,559
JBrowse link
G Cpb2 carboxypeptidase B2 increases expression EXP Diclofenac results in increased expression of CPB2 mRNA CTD PMID:26934552 NCBI chr14:75,479,727...75,520,995
Ensembl chr14:75,479,727...75,520,995
JBrowse link
G Cplx1 complexin 1 increases expression ISO Diclofenac results in increased expression of CPLX1 mRNA CTD PMID:30723492 NCBI chr 5:108,666,420...108,697,893
Ensembl chr 5:108,666,420...108,697,890
JBrowse link
G Cplx4 complexin 4 increases expression ISO Diclofenac results in increased expression of CPLX4 mRNA CTD PMID:30723492 NCBI chr18:66,088,793...66,103,249
Ensembl chr18:66,088,793...66,103,308
JBrowse link
G Cpne8 copine VIII increases expression EXP Diclofenac results in increased expression of CPNE8 mRNA CTD PMID:26934552 NCBI chr15:90,371,684...90,563,591
Ensembl chr15:90,371,685...90,563,635
JBrowse link
G Cpsf6 cleavage and polyadenylation specific factor 6 affects expression ISO Diclofenac affects the expression of CPSF6 mRNA CTD PMID:24752500 NCBI chr10:117,180,572...117,212,903
Ensembl chr10:117,180,578...117,215,920
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver increases expression ISO Diclofenac results in increased expression of CPT1A mRNA CTD PMID:19022234 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733
JBrowse link
G Cr1l complement C3b/C4b receptor 1 like multiple interactions ISO [Water deficiency co-treated with Diclofenac] results in decreased expression of CR1L protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in decreased expression of CR1L protein] CTD PMID:31042592 NCBI chr 1:194,781,019...194,813,878
Ensembl chr 1:194,779,690...194,813,894
JBrowse link
G Cr2 complement receptor 2 affects expression EXP Diclofenac affects the expression of CR2 mRNA CTD PMID:26934552 NCBI chr 1:194,819,120...194,859,096
Ensembl chr 1:194,819,119...194,859,024
JBrowse link
G Creb3l2 cAMP responsive element binding protein 3-like 2 increases expression EXP Diclofenac results in increased expression of CREB3L2 mRNA CTD PMID:26934552 NCBI chr 6:37,307,956...37,419,083
Ensembl chr 6:37,304,190...37,419,081
JBrowse link
G Creb3l4 cAMP responsive element binding protein 3-like 4 affects expression ISO Diclofenac affects the expression of CREB3L4 mRNA CTD PMID:24752500 NCBI chr 3:90,144,805...90,161,387
Ensembl chr 3:90,144,807...90,150,819
JBrowse link
G Crp C-reactive protein, pentraxin-related multiple interactions
decreases expression
ISO [Diclofenac co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CRP protein; Diclofenac inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CRP protein]; lipopolysaccharide, E coli O55-B5 inhibits the reaction [Diclofenac results in decreased expression of CRP protein]
Diclofenac inhibits the reaction [TNF protein results in increased expression of CRP mRNA]; Diclofenac inhibits the reaction [TNF protein results in increased secretion of CRP protein]
CTD PMID:25772430 PMID:27313093 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression EXP Diclofenac results in decreased expression of CRY1 mRNA CTD PMID:26934552 NCBI chr10:84,967,564...85,020,918
Ensembl chr10:84,967,564...85,020,928
JBrowse link
G Csf1 colony stimulating factor 1 (macrophage) decreases expression EXP Diclofenac results in decreased expression of CSF1 mRNA CTD PMID:26934552 PMID:35537566 NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785
JBrowse link
G Csf1r colony stimulating factor 1 receptor increases expression
increases secretion
EXP Diclofenac results in increased expression of CSF1R mRNA
Diclofenac results in increased secretion of CSF1R protein
CTD PMID:26934552 NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221
JBrowse link
G Csf2rb2 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) increases expression EXP Diclofenac results in increased expression of CSF2RB mRNA; Diclofenac results in increased expression of CSF2RB2 mRNA CTD PMID:26934552 NCBI chr15:78,166,707...78,189,921
Ensembl chr15:78,166,707...78,189,921
JBrowse link
G Csnk2a1 casein kinase 2, alpha 1 polypeptide affects expression ISO Diclofenac affects the expression of CSNK2A1 mRNA CTD PMID:24752500 NCBI chr 2:152,068,468...152,123,772
Ensembl chr 2:152,068,759...152,123,772
JBrowse link
G Csnk2a2 casein kinase 2, alpha prime polypeptide affects expression ISO Diclofenac affects the expression of CSNK2A2 mRNA CTD PMID:24752500 NCBI chr 8:96,172,724...96,215,505
Ensembl chr 8:96,172,724...96,216,667
JBrowse link
G Csrnp3 cysteine-serine-rich nuclear protein 3 increases expression ISO Diclofenac results in increased expression of CSRNP3 mRNA CTD PMID:30723492 NCBI chr 2:65,675,628...65,866,958
Ensembl chr 2:65,676,111...65,861,890
JBrowse link
G Cstf2 cleavage stimulation factor, 3' pre-RNA subunit 2 affects expression ISO Diclofenac affects the expression of CSTF2 mRNA CTD PMID:24752500 NCBI chr  X:132,959,925...132,987,571
Ensembl chr  X:132,959,936...132,987,568
JBrowse link
G Cstf3 cleavage stimulation factor, 3' pre-RNA, subunit 3 affects expression ISO Diclofenac affects the expression of CSTF3 mRNA CTD PMID:24752500 NCBI chr 2:104,420,829...104,495,770
Ensembl chr 2:104,420,868...104,495,774
JBrowse link
G Ctbp2 C-terminal binding protein 2 affects expression ISO Diclofenac affects the expression of CTBP2 mRNA CTD PMID:24752500 NCBI chr 7:132,588,727...132,726,048
Ensembl chr 7:132,589,292...132,726,083
JBrowse link
G Cth cystathionine gamma lyase affects expression
decreases expression
ISO
EXP
Diclofenac affects the expression of CTH mRNA
Diclofenac results in decreased expression of CTH mRNA
CTD PMID:24752500 PMID:35537566 NCBI chr 3:157,599,885...157,630,718
Ensembl chr 3:157,599,885...157,630,714
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 increases expression EXP Diclofenac results in increased expression of CTLA4 protein CTD PMID:26934552 NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991
JBrowse link
G Ctnnb1 catenin beta 1 affects expression ISO Diclofenac affects the expression of CTNNB1 mRNA CTD PMID:24752500 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Ctps1 cytidine 5'-triphosphate synthase 1 affects expression ISO Diclofenac affects the expression of CTPS1 mRNA CTD PMID:24752500 NCBI chr 4:120,397,065...120,427,473
Ensembl chr 4:120,397,065...120,427,473
JBrowse link
G Ctps2 cytidine 5'-triphosphate synthase 2 affects expression ISO Diclofenac affects the expression of CTPS2 mRNA CTD PMID:24752500 NCBI chr  X:161,684,264...161,817,537
Ensembl chr  X:161,684,234...161,815,504
JBrowse link
G Ctsc cathepsin C increases expression EXP Diclofenac results in increased expression of CTSC mRNA CTD PMID:26934552 NCBI chr 7:87,927,233...87,960,083
Ensembl chr 7:87,927,293...87,960,096
JBrowse link
G Ctse cathepsin E decreases expression EXP Diclofenac results in decreased expression of CTSE mRNA CTD PMID:35537566 NCBI chr 1:131,566,052...131,603,245
Ensembl chr 1:131,566,044...131,603,243
JBrowse link
G Ctsj cathepsin J increases expression EXP Diclofenac results in increased expression of CTSJ mRNA CTD PMID:26934552 NCBI chr13:61,147,993...61,153,739
Ensembl chr13:61,147,993...61,153,773
JBrowse link
G Ctss cathepsin S increases expression EXP Diclofenac results in increased expression of CTSS mRNA CTD PMID:26934552 NCBI chr 3:95,434,097...95,463,716
Ensembl chr 3:95,434,097...95,463,714
JBrowse link
G Cul3 cullin 3 affects expression ISO Diclofenac affects the expression of CUL3 mRNA CTD PMID:24752500 NCBI chr 1:80,242,640...80,318,426
Ensembl chr 1:80,242,640...80,318,197
JBrowse link
G Cul7 cullin 7 decreases expression EXP Diclofenac results in decreased expression of CUL7 mRNA CTD PMID:26934552 NCBI chr17:46,961,264...46,975,290
Ensembl chr17:46,961,263...46,975,290
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions ISO Diclofenac promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CXCL1 mRNA]; Diclofenac promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CXCL1 protein] CTD PMID:23939143 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974
JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 increases expression EXP Diclofenac results in increased expression of CXCL13 mRNA CTD PMID:26934552 NCBI chr 5:96,104,785...96,108,927
Ensembl chr 5:96,104,810...96,108,927
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 increases expression EXP Diclofenac results in increased expression of CXCL14 mRNA CTD PMID:26934552 NCBI chr13:56,436,456...56,444,624
Ensembl chr13:56,436,456...56,444,364
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 affects expression
increases secretion
increases expression
multiple interactions
decreases expression
ISO Diclofenac affects the expression of CXCL8 mRNA
Diclofenac analog results in increased secretion of CXCL8 protein
Diclofenac analog results in increased expression of CXCL8 mRNA; Diclofenac results in increased expression of CXCL8 mRNA
Diclofenac inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; Diclofenac inhibits the reaction [TNF protein results in increased secretion of CXCL8 protein]; Diclofenac promotes the reaction [Mustard Gas results in increased secretion of CXCL8 protein]; pyrazolanthrone inhibits the reaction [Diclofenac analog results in increased expression of CXCL8 mRNA]; SB 203580 inhibits the reaction [Diclofenac analog results in increased expression of CXCL8 mRNA]
Diclofenac results in decreased expression of CXCL8 mRNA; Diclofenac results in decreased expression of CXCL8 protein
CTD PMID:17379860 PMID:19192274 PMID:24104198 PMID:24752500 PMID:27313093 More... NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions
increases expression
ISO
EXP
Diclofenac promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CXCL2 mRNA]
Diclofenac results in increased expression of CXCL2 mRNA; Diclofenac results in increased expression of CXCL2 protein
CTD PMID:22285467 PMID:23939143 PMID:24747151 PMID:26934552 PMID:27671914 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression
decreases expression
EXP Diclofenac results in increased expression of CXCL1 mRNA; Diclofenac results in increased expression of CXCL1 protein
Diclofenac results in decreased expression of CXCL1 mRNA
CTD PMID:26934552 PMID:27671914 NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression ISO
EXP
Diclofenac results in decreased expression of CXCR4 mRNA CTD PMID:19192274 PMID:35537566 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030
JBrowse link
G Cyb561 cytochrome b-561 increases expression EXP Diclofenac results in increased expression of CYB561 mRNA CTD PMID:26934552 NCBI chr11:105,824,528...105,844,157
Ensembl chr11:105,824,528...105,844,162
JBrowse link
G Cyba cytochrome b-245, alpha polypeptide increases expression EXP Diclofenac results in increased expression of CYBA mRNA CTD PMID:26934552 NCBI chr 8:123,151,510...123,159,679
Ensembl chr 8:123,151,515...123,159,669
JBrowse link
G Cybb cytochrome b-245, beta polypeptide increases expression EXP Diclofenac results in increased expression of CYBB mRNA CTD PMID:26934552 NCBI chr  X:9,301,493...9,354,005
Ensembl chr  X:9,301,491...9,354,010
JBrowse link
G Cycs cytochrome c, somatic affects expression ISO Diclofenac affects the expression of CYCS mRNA CTD PMID:24752500 NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 increases expression EXP Diclofenac results in increased expression of CYP17A1 mRNA CTD PMID:26934552 NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in increased expression of CYP19A1 mRNA CTD PMID:37844793 NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
decreases activity
ISO
EXP
Diclofenac results in increased expression of CYP1A1 mRNA; Diclofenac results in increased expression of CYP1A1 protein
Diclofenac results in decreased activity of CYP1A1 protein
CTD PMID:18420780 PMID:21784029 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression
decreases activity
multiple interactions
ISO Diclofenac results in increased expression of CYP1A2 mRNA; Diclofenac results in increased expression of CYP1A2 protein
Diclofenac metabolite results in decreased activity of CYP1A2 protein
[CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Diclofenac
CTD PMID:21784029 PMID:23397584 PMID:28960974 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity EXP Diclofenac results in decreased activity of CYP1B1 protein CTD PMID:18420780 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 decreases expression EXP Diclofenac results in decreased expression of CYP26A1 mRNA CTD PMID:26934552 NCBI chr19:37,686,186...37,689,984
Ensembl chr19:37,686,246...37,689,984
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in increased expression of CYP26B1 mRNA CTD PMID:37844793 NCBI chr 6:84,548,396...84,570,890
Ensembl chr 6:84,548,396...84,570,890
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions EXP [Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in decreased expression of CYP27A1 mRNA; [Sodium Selenite co-treated with Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in decreased expression of CYP27A1 mRNA CTD PMID:38945390 NCBI chr 1:74,752,311...74,777,056
Ensembl chr 1:74,752,733...74,777,051
JBrowse link
G Cyp2a4 cytochrome P450, family 2, subfamily a, polypeptide 4 decreases activity
affects expression
EXP Diclofenac results in decreased activity of CYP2A4 protein
Diclofenac affects the expression of CYP2A4 mRNA
CTD PMID:18420780 PMID:26934552 NCBI chr 7:26,006,617...26,014,513
Ensembl chr 7:26,006,594...26,014,513
JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 affects expression EXP Diclofenac affects the expression of CYP2A5 mRNA CTD PMID:26934552 NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 decreases activity EXP Diclofenac results in decreased activity of CYP2B10 protein CTD PMID:18420780 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
JBrowse link
G Cyp2b9 cytochrome P450, family 2, subfamily b, polypeptide 9 increases expression EXP Diclofenac results in increased expression of CYP2B9 mRNA CTD PMID:26934552 NCBI chr 7:25,872,775...25,910,086
Ensembl chr 7:25,872,836...25,910,086
JBrowse link
G Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 decreases expression EXP Diclofenac results in decreased expression of CYP2C23 mRNA CTD PMID:26934552 NCBI chr19:43,993,461...44,017,695
Ensembl chr19:43,993,461...44,017,647
JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 decreases activity
increases hydroxylation
EXP
ISO
Diclofenac results in decreased activity of CYP2C29 protein
CYP2C6 protein results in increased hydroxylation of Diclofenac
CTD PMID:11911841 PMID:18420780 NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 multiple interactions
increases response to substance
increases hydroxylation
ISO [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Diclofenac; [CYP2C19 protein co-treated with CYP2C9 protein] results in increased hydroxylation of Diclofenac
CYP2C19 protein results in increased susceptibility to Diclofenac
CYP2C19 protein results in increased hydroxylation of Diclofenac
CTD PMID:15486075 PMID:18511451 PMID:23397584 PMID:28762043 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Cyp2c39 cytochrome P450, family 2, subfamily c, polypeptide 39 decreases activity EXP Diclofenac metabolite results in decreased activity of CYP2C39 protein CTD PMID:28960974 NCBI chr19:39,335,790...39,558,012
Ensembl chr19:39,499,306...39,556,973
JBrowse link
G Cyp2c40 cytochrome P450, family 2, subfamily c, polypeptide 40 affects expression EXP Diclofenac affects the expression of CYP2C40 mRNA CTD PMID:26934552 NCBI chr19:39,755,517...39,801,258
Ensembl chr19:39,755,515...39,801,258
JBrowse link
G Cyp2c55 cytochrome P450, family 2, subfamily c, polypeptide 55 decreases expression EXP Diclofenac results in decreased expression of CYP2C55 mRNA CTD PMID:26934552 NCBI chr19:38,995,384...39,031,134
Ensembl chr19:38,995,463...39,031,137
JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 decreases hydroxylation
decreases activity
increases hydroxylation
increases activity
increases oxidation
multiple interactions
increases metabolic processing
increases hydrolysis
affects binding
affects metabolic processing
affects hydrolysis
ISO
EXP
CYP2C9 gene polymorphism results in decreased hydroxylation of Diclofenac
Diclofenac results in decreased activity of CYP2C9 protein
CYP2C9 protein results in increased hydroxylation of Diclofenac
Diclofenac results in increased activity of CYP2C9 protein
CYP2C9 protein results in increased oxidation of Diclofenac
1-aminobenzotriazole inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Diclofenac]; 4-methylimidazole inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac]; [5-bromotryptamine analog results in decreased activity of CYP2C9 protein] which results in decreased metabolism of Diclofenac; [5-chlorotryptamine analog results in decreased activity of CYP2C9 protein] which results in decreased metabolism of Diclofenac; [5-fluoro-alpha-methyltryptamine results in decreased activity of CYP2C9 protein] which results in decreased metabolism of Diclofenac; [5-fluorotryptamine analog results in decreased activity of CYP2C9 protein] which results in decreased metabolism of Diclofenac; [5-methyltryptamine analog results in decreased activity of CYP2C9 protein] which results in decreased metabolism of Diclofenac; [7-methyltryptamine analog results in decreased activity of CYP2C9 protein] which results in decreased metabolism of Diclofenac; [[CYP2C9 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased hydroxylation of Diclofenac] which results in increased abundance of 4'-hydroxydiclofenac; [[Ticrynafen results in decreased activity of CYP2C9 protein] which affects the metabolism of Diclofenac] which affects the abundance of 4'-hydroxydiclofenac; [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Diclofenac; [CYP2C19 protein co-treated with CYP2C9 protein] results in increased hydroxylation of Diclofenac; [CYP2C9 mRNA results in increased metabolism of Diclofenac] which results in increased chemical synthesis of 4'-hydroxydiclofenac; [CYP2C9 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased hydroxylation of Diclofenac; [CYP2C9 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased metabolism of Diclofenac; [CYP2C9 protein results in increased hydroxylation of Diclofenac] which results in increased chemical synthesis of 4'-hydroxydiclofenac; [CYP2C9 protein results in increased metabolism of Diclofenac] which results in increased abundance of 4'-hydroxydiclofenac; [CYP2C9 protein results in increased metabolism of Diclofenac] which results in increased chemical synthesis of 4'-hydroxydiclofenac; [CYP3A4 protein co-treated with CYP2C9 protein co-treated with UGT2B7 protein] results in increased susceptibility to Diclofenac; [CYP3A4 protein co-treated with CYP2C9 protein] results in increased susceptibility to Diclofenac; [Fluconazole results in decreased activity of CYP2C9 protein] which results in decreased metabolism of Diclofenac; [Sulfaphenazole results in decreased activity of CYP2C9 protein] which results in decreased metabolism of Diclofenac; [Ticrynafen results in decreased activity of CYP2C9 protein] which affects the metabolism of Diclofenac; [Tryptamines analog results in decreased activity of CYP2C9 protein] which results in decreased metabolism of Diclofenac; Amiodarone inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac]; Benzbromarone inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac]; Clotrimazole inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac]; Cyclohexenes analog inhibits the reaction [CYP2C9 protein results in increased metabolism of Diclofenac]; CYP2C9 gene mutant form inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Diclofenac]; CYP2C9 protein results in increased hydroxylation of and results in increased susceptibility to Diclofenac; Fluconazole inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac]; Fluvastatin inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac]; Ibuprofen inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac]; Ketoconazole inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac]; Lansoprazole inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Diclofenac]; methysticin inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Diclofenac]; Miconazole inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac]; Omeprazole inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Diclofenac]; Pantoprazole inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Diclofenac]; perfluorooctane sulfonic acid inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Diclofenac]; Piroxicam inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac]; Quinine inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac]; rabeprazole-thioether inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Diclofenac]; Sertraline inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac]; sitaxsentan inhibits the reaction [CYP2C9 protein results in increased metabolism of Diclofenac]; Sulfaphenazole inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac]; Sulfaphenazole inhibits the reaction [CYP2C9 protein results in increased metabolism of Diclofenac]; Sulfinpyrazone inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac]; Ticrynafen inhibits the reaction [CYP2C9 protein results in increased metabolism of Diclofenac]; Tolbutamide inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac]; Warfarin inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac]; zafirlukast inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac]
CYP2C9 mRNA results in increased metabolism of Diclofenac; CYP2C9 protein results in increased metabolism of Diclofenac
CYP2C9 protein results in increased hydrolysis of Diclofenac
CYP2C9 protein binds to Diclofenac
CYP2C9 gene polymorphism affects the hydrolysis of Diclofenac
CTD PMID:9110362 PMID:9241660 PMID:9698079 PMID:10975605 PMID:10991840 More... NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
JBrowse link
G Cyp2c68 cytochrome P450, family 2, subfamily c, polypeptide 68 decreases expression EXP Diclofenac results in decreased expression of CYP2C68 mRNA CTD PMID:26934552 NCBI chr19:39,677,280...39,729,545
Ensembl chr19:39,677,278...39,729,498
JBrowse link
G Cyp2c70 cytochrome P450, family 2, subfamily c, polypeptide 70 increases expression EXP Diclofenac results in increased expression of CYP2C70 mRNA CTD PMID:26934552 NCBI chr19:40,141,805...40,175,730
Ensembl chr19:40,141,797...40,175,777
JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 multiple interactions ISO [[CYP2D6 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased hydroxylation of Diclofenac] which results in increased abundance of 4'-hydroxydiclofenac; [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Diclofenac; [CYP2D6 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased hydroxylation of Diclofenac CTD PMID:23397584 PMID:24246759 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO Diclofenac metabolite results in decreased activity of CYP2E1 protein CTD PMID:28960974 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Cyp2j13 cytochrome P450, family 2, subfamily j, polypeptide 13 increases expression EXP Diclofenac results in increased expression of CYP2J13 mRNA CTD PMID:26934552 NCBI chr 4:95,930,897...95,965,803
Ensembl chr 4:95,915,771...95,965,783
JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 increases expression EXP Diclofenac results in increased expression of CYP39A1 mRNA CTD PMID:26934552 NCBI chr17:43,978,263...44,062,322
Ensembl chr17:43,978,316...44,062,322
JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 decreases activity EXP Diclofenac metabolite results in decreased activity of CYP3A11 protein CTD PMID:28960974 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774
JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 decreases activity
increases expression
EXP Diclofenac metabolite results in decreased activity of CYP3A13 protein
Diclofenac results in increased expression of CYP3A13 mRNA
CTD PMID:26934552 PMID:28960974 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881
JBrowse link
G Cyp3a44 cytochrome P450, family 3, subfamily a, polypeptide 44 increases expression
decreases activity
EXP Diclofenac results in increased expression of CYP3A44 mRNA
Diclofenac results in decreased activity of CYP3A4 protein
CTD PMID:18420780 PMID:26934552 NCBI chr 5:145,710,793...145,742,701
Ensembl chr 5:145,710,793...145,742,684
JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 increases hydroxylation ISO CYP46A1 protein results in increased hydroxylation of Diclofenac CTD PMID:14640697 NCBI chr12:108,300,568...108,328,497
Ensembl chr12:108,300,640...108,328,493
JBrowse link
G Cyp4a12a cytochrome P450, family 4, subfamily a, polypeptide 12a decreases expression EXP Diclofenac results in decreased expression of CYP4A12A mRNA CTD PMID:26934552 NCBI chr 4:115,156,243...115,190,012
Ensembl chr 4:115,156,243...115,190,012
JBrowse link
G Cyp4a31 cytochrome P450, family 4, subfamily a, polypeptide 31 decreases expression EXP Diclofenac results in decreased expression of CYP4A31 mRNA CTD PMID:26934552 NCBI chr 4:115,420,824...115,436,212
Ensembl chr 4:115,420,846...115,436,212
JBrowse link
G Cyp4f39 cytochrome P450, family 4, subfamily f, polypeptide 39 decreases expression EXP Diclofenac results in decreased expression of CYP4F39 mRNA CTD PMID:35537566 NCBI chr17:32,671,670...32,712,294
Ensembl chr17:32,671,697...32,712,294
JBrowse link
G Cyp4v3 cytochrome P450, family 4, subfamily v, polypeptide 3 decreases expression EXP Diclofenac results in decreased expression of CYP4V3 mRNA CTD PMID:26934552 NCBI chr 8:45,758,838...45,786,200
Ensembl chr 8:45,757,981...45,786,253
JBrowse link
G Cyp51 cytochrome P450, family 51 decreases activity
increases expression
EXP Diclofenac metabolite results in decreased activity of CYP51A1 protein
Diclofenac results in increased expression of CYP51 mRNA
CTD PMID:26934552 PMID:28960974 NCBI chr 5:4,130,674...4,154,697
Ensembl chr 5:4,131,145...4,154,746
JBrowse link
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 increases expression
multiple interactions
EXP Diclofenac results in increased expression of CYP7A1 mRNA; Diclofenac results in increased expression of CYP7A1 protein
[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in decreased expression of CYP7A1 mRNA; Sodium Selenite inhibits the reaction [[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in decreased expression of CYP7A1 mRNA]
CTD PMID:26934552 PMID:38815664 PMID:38945390 NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633
JBrowse link
G Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 decreases expression EXP Diclofenac results in decreased expression of CYP8B1 mRNA CTD PMID:26934552 NCBI chr 9:121,743,422...121,745,371
Ensembl chr 9:121,743,422...121,745,371
JBrowse link
G Dap death-associated protein increases expression EXP Diclofenac results in increased expression of DAP mRNA CTD PMID:26934552 NCBI chr15:31,224,531...31,274,484
Ensembl chr15:31,224,460...31,274,487
JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 affects expression ISO Diclofenac affects the expression of DBT mRNA CTD PMID:24752500 NCBI chr 3:116,306,776...116,343,630
Ensembl chr 3:116,306,719...116,343,630
JBrowse link
G Dctpp1 dCTP pyrophosphatase 1 affects expression ISO Diclofenac affects the expression of DCTPP1 mRNA CTD PMID:24752500 NCBI chr 7:126,856,131...126,859,839
Ensembl chr 7:126,856,131...126,859,881
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases response to substance
decreases expression
increases expression
EXP
ISO
DDIT3 results in increased susceptibility to Diclofenac
Diclofenac results in decreased expression of DDIT3 mRNA
Diclofenac results in increased expression of DDIT3 mRNA; Diclofenac results in increased expression of DDIT3 protein
CTD PMID:18172885 PMID:20668000 PMID:24752500 PMID:27313093 PMID:27358234 More... NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression EXP Diclofenac results in increased expression of DDIT4 mRNA CTD PMID:26934552 NCBI chr10:59,785,497...59,787,592
Ensembl chr10:59,785,491...59,787,656
JBrowse link
G Ddr1 discoidin domain receptor family, member 1 affects expression ISO Diclofenac affects the expression of DDR1 mRNA CTD PMID:24752500 NCBI chr17:35,992,459...36,015,633
Ensembl chr17:35,992,459...36,015,513
JBrowse link
G Ddt D-dopachrome tautomerase decreases expression EXP Diclofenac results in decreased expression of DDT mRNA CTD PMID:26934552 NCBI chr10:75,607,067...75,609,208
Ensembl chr10:75,607,064...75,609,248
JBrowse link
G Ddx5 DEAD box helicase 5 affects expression ISO Diclofenac affects the expression of DDX5 mRNA CTD PMID:24752500 NCBI chr11:106,671,181...106,680,011
Ensembl chr11:106,671,181...106,680,011
JBrowse link
G Decr1 2,4-dienoyl CoA reductase 1, mitochondrial increases expression ISO Diclofenac results in increased expression of DECR1 protein CTD PMID:25772430 NCBI chr 4:15,917,240...15,945,377
Ensembl chr 4:15,917,240...15,945,507
JBrowse link
G Dennd2d DENN domain containing 2D decreases expression EXP Diclofenac results in decreased expression of DENND2D mRNA CTD PMID:35537566 NCBI chr 3:106,389,745...106,410,346
Ensembl chr 3:106,389,721...106,410,346
JBrowse link
G Derl1 Der1-like domain family, member 1 increases expression EXP Diclofenac results in increased expression of DERL1 mRNA CTD PMID:26934552 NCBI chr15:57,732,898...57,755,814
Ensembl chr15:57,732,898...57,755,844
JBrowse link
G Derl3 Der1-like domain family, member 3 increases expression EXP Diclofenac results in increased expression of DERL3 mRNA CTD PMID:26934552 NCBI chr10:75,729,232...75,731,775
Ensembl chr10:75,729,247...75,731,775
JBrowse link
G Dffa DNA fragmentation factor, alpha subunit affects expression ISO Diclofenac affects the expression of DFFA mRNA CTD PMID:24752500 NCBI chr 4:149,188,599...149,205,110
Ensembl chr 4:149,188,603...149,205,104
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase increases expression EXP Diclofenac results in increased expression of DHCR24 mRNA CTD PMID:26934552 NCBI chr 4:106,418,279...106,446,310
Ensembl chr 4:106,418,235...106,446,310
JBrowse link
G Dhfr dihydrofolate reductase affects expression ISO Diclofenac affects the expression of DHFR mRNA CTD PMID:24752500 NCBI chr13:92,491,291...92,525,561
Ensembl chr13:92,491,234...92,525,561
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 decreases expression EXP Diclofenac results in decreased expression of DHRS3 mRNA CTD PMID:35537566 NCBI chr 4:144,618,712...144,654,214
Ensembl chr 4:144,619,397...144,654,779
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 affects expression ISO Diclofenac affects the expression of DKK1 mRNA CTD PMID:24752500 NCBI chr19:30,523,276...30,526,896
Ensembl chr19:30,523,263...30,527,065
JBrowse link
G Dnaaf2 dynein, axonemal assembly factor 2 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of DNAAF2 mRNA CTD PMID:37844793 NCBI chr12:69,235,861...69,245,203
Ensembl chr12:69,235,861...69,245,203
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 affects expression ISO Diclofenac affects the expression of DNAJA1 mRNA CTD PMID:24752500 NCBI chr 4:40,722,468...40,734,965
Ensembl chr 4:40,722,150...40,737,149
JBrowse link
G Dnaja2 DnaJ heat shock protein family (Hsp40) member A2 affects expression ISO Diclofenac affects the expression of DNAJA2 mRNA CTD PMID:24752500 NCBI chr 8:86,264,262...86,281,990
Ensembl chr 8:86,264,262...86,281,973
JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 affects expression
decreases expression
ISO
EXP
Diclofenac affects the expression of DNAJA3 mRNA
Diclofenac results in decreased expression of DNAJA3 mRNA
CTD PMID:24752500 PMID:26934552 NCBI chr16:4,501,934...4,525,559
Ensembl chr16:4,457,853...4,525,559
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 affects expression ISO Diclofenac affects the expression of DNAJB1 mRNA CTD PMID:24752500 NCBI chr 8:84,334,804...84,339,282
Ensembl chr 8:84,334,822...84,339,282
JBrowse link
G Dnajb14 DnaJ heat shock protein family (Hsp40) member B14 affects expression ISO Diclofenac affects the expression of DNAJB14 mRNA CTD PMID:24752500 NCBI chr 3:137,572,801...137,619,350
Ensembl chr 3:137,573,436...137,622,318
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 affects expression ISO Diclofenac affects the expression of DNAJB4 mRNA CTD PMID:24752500 NCBI chr 3:151,887,217...151,915,720
Ensembl chr 3:151,884,148...151,915,939
JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 affects expression ISO Diclofenac affects the expression of DNAJB6 mRNA CTD PMID:24752500 NCBI chr 5:29,940,896...29,991,476
Ensembl chr 5:29,940,686...30,023,132
JBrowse link
G Dnajb7 DnaJ heat shock protein family (Hsp40) member B7 increases expression ISO Diclofenac results in increased expression of DNAJB7 mRNA CTD PMID:30723492 NCBI chr15:81,291,289...81,292,474
Ensembl chr15:81,291,127...81,292,500
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 affects expression
increases expression
ISO
EXP
Diclofenac affects the expression of DNAJB9 mRNA
Diclofenac results in increased expression of DNAJB9 mRNA
CTD PMID:24752500 PMID:26934552 NCBI chr12:44,252,680...44,256,851
Ensembl chr12:44,252,342...44,257,109
JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 affects expression
increases expression
ISO
EXP
Diclofenac affects the expression of DNAJC10 mRNA
Diclofenac results in increased expression of DNAJC10 mRNA
CTD PMID:24752500 PMID:26934552 NCBI chr 2:80,145,790...80,184,399
Ensembl chr 2:80,145,810...80,184,387
JBrowse link
G Dnajc11 DnaJ heat shock protein family (Hsp40) member C11 affects expression ISO Diclofenac affects the expression of DNAJC11 mRNA CTD PMID:24752500 NCBI chr 4:152,018,177...152,066,416
Ensembl chr 4:152,018,148...152,066,594
JBrowse link
G Dnajc12 DnaJ heat shock protein family (Hsp40) member C12 increases expression
decreases expression
EXP Diclofenac results in increased expression of DNAJC12 mRNA
Diclofenac results in decreased expression of DNAJC12 mRNA
CTD PMID:26934552 NCBI chr10:63,218,222...63,244,619
Ensembl chr10:63,218,222...63,246,355
JBrowse link
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 affects expression ISO Diclofenac affects the expression of DNAJC15 mRNA CTD PMID:24752500 NCBI chr14:78,063,657...78,112,357
Ensembl chr14:78,058,121...78,112,565
JBrowse link
G Dnajc18 DnaJ heat shock protein family (Hsp40) member C18 affects expression ISO Diclofenac affects the expression of DNAJC18 mRNA CTD PMID:24752500 NCBI chr18:35,804,156...35,841,467
Ensembl chr18:35,804,156...35,841,467
JBrowse link
G Dnajc21 DnaJ heat shock protein family (Hsp40) member C21 affects expression ISO Diclofenac affects the expression of DNAJC21 mRNA CTD PMID:24752500 NCBI chr15:10,446,849...10,470,685
Ensembl chr15:10,446,842...10,470,602
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 increases expression EXP Diclofenac results in increased expression of DNAJC3 mRNA CTD PMID:26934552 NCBI chr14:119,175,371...119,219,114
Ensembl chr14:119,175,388...119,219,109
JBrowse link
G Dnajc5 DnaJ heat shock protein family (Hsp40) member C5 affects expression ISO Diclofenac affects the expression of DNAJC5 mRNA CTD PMID:24752500 NCBI chr 2:181,162,141...181,194,679
Ensembl chr 2:181,162,278...181,196,926
JBrowse link
G Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 affects expression ISO Diclofenac affects the expression of DNAJC6 mRNA CTD PMID:24752500 NCBI chr 4:101,353,751...101,499,996
Ensembl chr 4:101,353,828...101,499,996
JBrowse link
G Dnajc7 DnaJ heat shock protein family (Hsp40) member C7 affects expression ISO Diclofenac affects the expression of DNAJC7 mRNA CTD PMID:24752500 NCBI chr11:100,473,644...100,511,030
Ensembl chr11:100,473,644...100,511,014
JBrowse link
G Dnajc8 DnaJ heat shock protein family (Hsp40) member C8 affects expression ISO Diclofenac affects the expression of DNAJC8 mRNA CTD PMID:24752500 NCBI chr 4:132,262,859...132,281,053
Ensembl chr 4:132,262,861...132,281,053
JBrowse link
G Dnajc9 DnaJ heat shock protein family (Hsp40) member C9 affects expression ISO Diclofenac affects the expression of DNAJC9 mRNA CTD PMID:24752500 NCBI chr14:20,434,706...20,438,978
Ensembl chr14:20,434,706...20,438,978
JBrowse link
G Dnd1 DND microRNA-mediated repression inhibitor 1 increases expression EXP Diclofenac results in increased expression of DND1 mRNA CTD PMID:35537566 NCBI chr18:36,896,724...36,899,267
Ensembl chr18:36,896,724...36,899,267
JBrowse link
G Dner delta/notch-like EGF repeat containing decreases expression EXP Diclofenac results in decreased expression of DNER mRNA CTD PMID:35537566 NCBI chr 1:84,347,560...84,673,942
Ensembl chr 1:84,347,560...84,673,942
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 affects expression ISO Diclofenac affects the expression of DPYSL2 mRNA CTD PMID:24752500 NCBI chr14:67,040,313...67,148,490
Ensembl chr14:67,040,313...67,148,410
JBrowse link
G Drd1 dopamine receptor D1 increases expression EXP Diclofenac results in increased expression of DRD1 mRNA CTD PMID:26934552 NCBI chr13:54,205,202...54,209,677
Ensembl chr13:54,205,202...54,209,724
JBrowse link
G Dtymk deoxythymidylate kinase affects expression ISO Diclofenac affects the expression of DTYMK mRNA CTD PMID:24752500 NCBI chr 1:93,720,298...93,730,246
Ensembl chr 1:93,720,298...93,729,656
JBrowse link
G Dusp1 dual specificity phosphatase 1 affects expression
decreases expression
ISO
EXP
Diclofenac affects the expression of DUSP1 mRNA
Diclofenac results in decreased expression of DUSP1 mRNA
CTD PMID:24752500 PMID:26934552 NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
JBrowse link
G Dut deoxyuridine triphosphatase affects expression ISO Diclofenac affects the expression of DUT mRNA CTD PMID:24752500 NCBI chr 2:125,089,168...125,100,969
Ensembl chr 2:125,089,110...125,100,528
JBrowse link
G Dync1i1 dynein cytoplasmic 1 intermediate chain 1 increases expression ISO Diclofenac results in increased expression of DYNC1I1 mRNA CTD PMID:30723492 NCBI chr 6:5,725,772...6,028,030
Ensembl chr 6:5,725,639...6,028,039
JBrowse link
G E2f1 E2F transcription factor 1 affects expression ISO Diclofenac affects the expression of E2F1 mRNA CTD PMID:24752500 NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812
JBrowse link
G E2f2 E2F transcription factor 2 affects expression ISO Diclofenac affects the expression of E2F2 mRNA CTD PMID:24752500 NCBI chr 4:135,899,585...135,923,368
Ensembl chr 4:135,899,705...135,923,368
JBrowse link
G E2f5 E2F transcription factor 5 affects expression ISO Diclofenac affects the expression of E2F5 mRNA CTD PMID:24752500 NCBI chr 3:14,638,370...14,671,369
Ensembl chr 3:14,643,701...14,671,369
JBrowse link
G Ecm1 extracellular matrix protein 1 decreases expression EXP Diclofenac results in decreased expression of ECM1 mRNA CTD PMID:26934552 NCBI chr 3:95,641,459...95,646,880
Ensembl chr 3:95,641,459...95,646,881
JBrowse link
G Ect2 ect2 oncogene increases expression EXP Diclofenac results in increased expression of ECT2 mRNA CTD PMID:26934552 NCBI chr 3:27,151,371...27,207,971
Ensembl chr 3:27,151,371...27,208,027
JBrowse link
G Edem1 ER degradation enhancer, mannosidase alpha-like 1 increases expression EXP Diclofenac results in increased expression of EDEM1 mRNA CTD PMID:26934552 NCBI chr 6:108,800,984...108,836,317
Ensembl chr 6:108,805,602...108,836,317
JBrowse link
G Edil3 EGF-like repeats and discoidin I-like domains 3 decreases expression EXP Diclofenac results in decreased expression of EDIL3 mRNA CTD PMID:26934552 NCBI chr13:88,969,591...89,471,344
Ensembl chr13:88,969,591...89,471,342
JBrowse link
G Edn1 endothelin 1 multiple interactions EXP Diclofenac inhibits the reaction [EDN1 protein results in decreased transport of Potassium] CTD PMID:15083534 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Edn2 endothelin 2 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of EDN2 mRNA CTD PMID:37844793 NCBI chr 4:120,018,403...120,024,557
Ensembl chr 4:120,018,403...120,024,557
JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase decreases expression EXP Diclofenac results in decreased expression of EEF2K mRNA CTD PMID:35537566 NCBI chr 7:120,442,080...120,506,441
Ensembl chr 7:120,442,054...120,506,673
JBrowse link
G Egf epidermal growth factor increases expression EXP Diclofenac results in increased expression of EGF protein CTD PMID:23506792 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965
JBrowse link
G Egfr epidermal growth factor receptor increases expression EXP Diclofenac results in increased expression of EGFR mRNA CTD PMID:26934552 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Egr1 early growth response 1 increases expression
multiple interactions
affects expression
ISO
EXP
Diclofenac results in increased expression of EGR1 mRNA
[Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of EGR1 mRNA
Diclofenac affects the expression of EGR1 mRNA
CTD PMID:15509713 PMID:26934552 PMID:37844793 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Eif1 eukaryotic translation initiation factor 1 affects expression ISO Diclofenac affects the expression of EIF1 mRNA CTD PMID:24752500 NCBI chr11:100,210,775...100,212,925
Ensembl chr11:100,210,711...100,212,922
JBrowse link
G Eif1a eukaryotic translation initiation factor 1A increases expression EXP Diclofenac results in increased expression of EIF1A mRNA CTD PMID:26934552 NCBI chr18:46,730,771...46,743,292
Ensembl chr18:46,730,768...46,749,523
JBrowse link
G Eif1ax eukaryotic translation initiation factor 1A, X-linked affects expression ISO Diclofenac affects the expression of EIF1AX mRNA CTD PMID:24752500 NCBI chr  X:158,155,174...158,172,617
Ensembl chr  X:158,155,174...158,172,924
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A affects expression ISO Diclofenac affects the expression of EIF2A mRNA CTD PMID:24752500 NCBI chr 3:58,433,252...58,464,922
Ensembl chr 3:58,433,242...58,464,922
JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 affects expression
decreases expression
ISO
EXP
Diclofenac affects the expression of EIF2AK1 mRNA
Diclofenac results in decreased expression of EIF2AK1 mRNA
CTD PMID:24752500 PMID:26934552 NCBI chr 5:143,803,586...143,839,535
Ensembl chr 5:143,803,543...143,841,069
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 affects expression
increases expression
increases phosphorylation
multiple interactions
increases activity
ISO
EXP
Diclofenac affects the expression of EIF2AK3 mRNA
Diclofenac results in increased expression of EIF2AK3 mRNA
Diclofenac results in increased phosphorylation of EIF2AK3 protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Diclofenac results in increased phosphorylation of EIF2AK3 protein]; 2-aminoethoxydiphenyl borate inhibits the reaction [Diclofenac results in increased phosphorylation of EIF2AK3 protein]; Calcium promotes the reaction [Diclofenac results in increased phosphorylation of EIF2AK3 protein]
Diclofenac results in increased activity of EIF2AK3 protein
CTD PMID:24752500 PMID:26609140 PMID:26934552 NCBI chr 6:70,821,468...70,882,225
Ensembl chr 6:70,821,499...70,882,229
JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 affects expression ISO Diclofenac affects the expression of EIF2AK4 mRNA CTD PMID:24752500 NCBI chr 2:118,219,065...118,305,715
Ensembl chr 2:118,219,099...118,305,715
JBrowse link
G Eif2b1 eukaryotic translation initiation factor 2B, subunit alpha affects expression ISO Diclofenac affects the expression of EIF2B1 mRNA CTD PMID:24752500 NCBI chr 5:124,708,277...124,717,194
Ensembl chr 5:124,708,276...124,717,194
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha affects expression
multiple interactions
ISO Diclofenac affects the expression of EIF2S1 mRNA
[TNF protein co-treated with Diclofenac] results in increased phosphorylation of EIF2S1 protein
CTD PMID:24752500 PMID:27313093 NCBI chr12:78,908,846...78,933,784
Ensembl chr12:78,908,593...78,933,784
JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit 2 beta affects expression ISO Diclofenac affects the expression of EIF2S2 mRNA CTD PMID:24752500 NCBI chr 2:154,713,330...154,734,826
Ensembl chr 2:154,713,330...154,734,855
JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A affects expression ISO Diclofenac affects the expression of EIF3A mRNA CTD PMID:24752500 NCBI chr19:60,749,554...60,779,131
Ensembl chr19:60,749,555...60,779,096
JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B affects expression ISO Diclofenac affects the expression of EIF3B mRNA CTD PMID:24752500 NCBI chr 5:140,405,060...140,429,113
Ensembl chr 5:140,405,083...140,429,115
JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C affects expression ISO Diclofenac affects the expression of EIF3C mRNA CTD PMID:24752500 NCBI chr 7:126,146,083...126,165,538
Ensembl chr 7:126,145,627...126,165,583
JBrowse link
G Eif4a1 eukaryotic translation initiation factor 4A1 affects expression ISO Diclofenac affects the expression of EIF4A1 mRNA CTD PMID:24752500 NCBI chr11:69,557,762...69,563,249
Ensembl chr11:69,557,762...69,563,249
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 affects expression ISO Diclofenac affects the expression of EIF4A2 mRNA CTD PMID:24752500 NCBI chr16:22,924,846...22,932,882
Ensembl chr16:22,926,194...22,932,886
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression
decreases expression
affects expression
ISO
EXP
Diclofenac results in increased expression of EIF4EBP1 mRNA
Diclofenac results in decreased expression of EIF4EBP1 mRNA
Diclofenac affects the expression of EIF4EBP1 mRNA
CTD PMID:18172885 PMID:24752500 PMID:35537566 NCBI chr 8:27,750,355...27,765,684
Ensembl chr 8:27,750,357...27,766,702
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4, gamma 1 affects expression ISO Diclofenac affects the expression of EIF4G1 mRNA CTD PMID:24752500 NCBI chr16:20,491,457...20,511,633
Ensembl chr16:20,487,063...20,511,634
JBrowse link
G Eif4g3 eukaryotic translation initiation factor 4 gamma, 3 affects expression ISO Diclofenac affects the expression of EIF4G3 mRNA CTD PMID:24752500 NCBI chr 4:137,719,090...137,934,397
Ensembl chr 4:137,720,333...137,935,819
JBrowse link
G Eif5 eukaryotic translation initiation factor 5 affects expression ISO Diclofenac affects the expression of EIF5 mRNA CTD PMID:24752500 NCBI chr12:111,504,535...111,513,187
Ensembl chr12:111,504,450...111,513,186
JBrowse link
G Elf2 E74-like factor 2 affects expression ISO Diclofenac affects the expression of ELF2 mRNA CTD PMID:24752500 NCBI chr 3:51,160,141...51,248,101
Ensembl chr 3:51,160,141...51,248,084
JBrowse link
G Elf3 E74-like factor 3 affects expression ISO Diclofenac affects the expression of ELF3 mRNA CTD PMID:24752500 NCBI chr 1:135,181,312...135,186,210
Ensembl chr 1:135,181,313...135,186,306
JBrowse link
G Elovl2 ELOVL fatty acid elongase 2 affects expression ISO Diclofenac affects the expression of ELOVL2 mRNA CTD PMID:24752500 NCBI chr13:41,335,858...41,373,879
Ensembl chr13:41,335,857...41,373,881
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 increases expression EXP Diclofenac results in increased expression of ELOVL6 mRNA CTD PMID:35537566 NCBI chr 3:129,326,035...129,432,144
Ensembl chr 3:129,326,004...129,432,144
JBrowse link
G Eme2 essential meiotic structure-specific endonuclease subunit 2 increases expression EXP Diclofenac results in increased expression of EME2 mRNA CTD PMID:26934552 NCBI chr17:25,111,126...25,114,061
Ensembl chr17:25,107,460...25,114,061
JBrowse link
G Endog endonuclease G affects expression ISO Diclofenac affects the expression of ENDOG mRNA CTD PMID:24752500 NCBI chr 2:30,061,525...30,064,057
Ensembl chr 2:30,061,505...30,064,081
JBrowse link
G Eno1 enolase 1, alpha non-neuron increases expression EXP Diclofenac results in increased expression of ENO1 mRNA CTD PMID:26934552 NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336
Ensembl chr18:150,321,178...150,333,336
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 affects expression ISO Diclofenac affects the expression of ENPP1 mRNA CTD PMID:24752500 NCBI chr10:24,513,812...24,588,057
Ensembl chr10:24,513,812...24,588,057
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 increases expression EXP Diclofenac results in increased expression of ENPP2 mRNA CTD PMID:26934552 NCBI chr15:54,702,297...54,816,284
Ensembl chr15:54,702,297...54,816,288
JBrowse link
G Entpd4 ectonucleoside triphosphate diphosphohydrolase 4 affects expression ISO Diclofenac affects the expression of ENTPD4 mRNA CTD PMID:24752500 NCBI chr14:69,574,600...69,604,191
Ensembl chr14:69,574,623...69,604,719
JBrowse link
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 affects expression ISO Diclofenac affects the expression of ENTPD5 mRNA CTD PMID:24752500 NCBI chr12:84,420,649...84,455,803
Ensembl chr12:84,420,631...84,455,803
JBrowse link
G Entpd7 ectonucleoside triphosphate diphosphohydrolase 7 affects expression ISO Diclofenac affects the expression of ENTPD7 mRNA CTD PMID:24752500 NCBI chr19:43,678,128...43,722,292
Ensembl chr19:43,678,111...43,722,136
JBrowse link
G Epas1 endothelial PAS domain protein 1 decreases expression ISO Diclofenac results in decreased expression of EPAS1 protein CTD PMID:12912967 NCBI chr17:87,061,292...87,140,838
Ensembl chr17:87,061,128...87,140,838
JBrowse link
G Epc2 enhancer of polycomb homolog 2 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in increased expression of EPC2 mRNA CTD PMID:37844793 NCBI chr 2:49,341,498...49,441,954
Ensembl chr 2:49,341,498...49,441,960
JBrowse link
G Ephx1 epoxide hydrolase 1, microsomal decreases expression ISO Diclofenac results in decreased expression of EPHX1 mRNA CTD PMID:17202759 NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469
JBrowse link
G Epn2 epsin 2 affects expression ISO Diclofenac affects the expression of EPN2 mRNA CTD PMID:24752500 NCBI chr11:61,406,709...61,470,560
Ensembl chr11:61,408,075...61,470,513
JBrowse link
G Epn3 epsin 3 affects expression ISO Diclofenac affects the expression of EPN3 mRNA CTD PMID:24752500 NCBI chr11:94,380,425...94,390,800
Ensembl chr11:94,380,425...94,390,800
JBrowse link
G Epo erythropoietin affects expression ISO Diclofenac affects the expression of EPO mRNA CTD PMID:24752500 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in increased expression of ERBB4 mRNA CTD PMID:37844793 NCBI chr 1:68,071,063...69,147,756
Ensembl chr 1:68,071,345...69,147,218
JBrowse link
G Ereg epiregulin increases expression ISO Diclofenac results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr 5:91,222,476...91,241,508
Ensembl chr 5:91,222,481...91,241,505
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signalling 1 affects expression ISO Diclofenac affects the expression of ERN1 mRNA CTD PMID:24752500 NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression EXP Diclofenac results in increased expression of ERO1A mRNA CTD PMID:26934552 NCBI chr14:45,520,544...45,556,029
Ensembl chr14:45,520,544...45,556,228
JBrowse link
G Esr1 estrogen receptor 1 (alpha) affects activity ISO Diclofenac affects the activity of ESR1 protein CTD PMID:29777833 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
JBrowse link
G Etnppl ethanolamine phosphate phospholyase decreases expression EXP Diclofenac results in decreased expression of ETNPPL mRNA CTD PMID:26934552 NCBI chr 3:130,411,097...130,429,399
Ensembl chr 3:130,411,097...130,431,170
JBrowse link
G Evi5 ecotropic viral integration site 5 decreases expression EXP Diclofenac results in decreased expression of EVI5 mRNA CTD PMID:35537566 NCBI chr 5:107,892,661...108,022,973
Ensembl chr 5:107,892,661...108,022,973
JBrowse link
G Extl1 exostosin-like glycosyltransferase 1 decreases expression EXP Diclofenac results in decreased expression of EXTL1 mRNA CTD PMID:35537566 NCBI chr 4:134,083,684...134,099,893
Ensembl chr 4:134,083,683...134,111,161
JBrowse link
G Eya4 EYA transcriptional coactivator and phosphatase 4 decreases expression EXP Diclofenac results in decreased expression of EYA4 mRNA CTD PMID:26934552 NCBI chr10:22,978,861...23,226,785
Ensembl chr10:22,978,862...23,226,684
JBrowse link
G F13a1 coagulation factor XIII, A1 subunit increases expression EXP Diclofenac results in increased expression of F13A1 mRNA CTD PMID:26934552 NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220
JBrowse link
G Faap24 Fanconi anemia core complex associated protein 24 increases expression EXP Diclofenac results in increased expression of FAAP24 mRNA CTD PMID:26934552 NCBI chr 7:35,091,577...35,096,192
Ensembl chr 7:35,091,577...35,096,261
JBrowse link
G Fabp1 fatty acid binding protein 1, liver decreases expression
increases expression
ISO
EXP
Diclofenac results in decreased expression of FABP1 mRNA
Diclofenac results in increased expression of FABP1 protein
CTD PMID:19022234 PMID:23506792 NCBI chr 6:71,176,863...71,182,018
Ensembl chr 6:71,176,811...71,182,007
JBrowse link
G Fabp2 fatty acid binding protein 2, intestinal decreases expression ISO
EXP
Diclofenac results in decreased expression of FABP2 mRNA CTD PMID:19022234 PMID:26934552 NCBI chr 3:122,688,721...122,693,155
Ensembl chr 3:122,688,721...122,693,155
JBrowse link
G Fabp3 fatty acid binding protein 3, muscle and heart multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of FABP3 mRNA CTD PMID:37844793 NCBI chr 4:130,202,531...130,209,256
Ensembl chr 4:130,202,388...130,209,256
JBrowse link
G Fabp4 fatty acid binding protein 4, adipocyte decreases expression EXP Diclofenac results in decreased expression of FABP4 mRNA CTD PMID:35537566 NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636
JBrowse link
G Fabp5 fatty acid binding protein 5, epidermal increases expression EXP Diclofenac results in increased expression of FABP5 mRNA CTD PMID:26934552 NCBI chr 3:10,077,645...10,081,670
Ensembl chr 3:10,077,608...10,081,667
JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression EXP Diclofenac results in decreased expression of FADS1 mRNA CTD PMID:26934552 NCBI chr19:10,160,245...10,174,238
Ensembl chr19:10,160,252...10,174,241
JBrowse link
G Fam209 family with sequence similarity 209 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of FAM209 mRNA CTD PMID:37844793 NCBI chr 2:172,314,474...172,316,236
Ensembl chr 2:172,314,440...172,316,251
JBrowse link
G Fancb Fanconi anemia, complementation group B affects expression ISO Diclofenac affects the expression of FANCB mRNA CTD PMID:24752500 NCBI chr  X:163,763,678...163,780,266
Ensembl chr  X:163,763,588...163,780,268
JBrowse link
G Fancc Fanconi anemia, complementation group C affects expression ISO Diclofenac affects the expression of FANCC mRNA CTD PMID:24752500 NCBI chr13:63,452,519...63,645,126
Ensembl chr13:63,432,857...63,645,092
JBrowse link
G Fance Fanconi anemia, complementation group E increases expression EXP Diclofenac results in increased expression of FANCE mRNA CTD PMID:26934552 NCBI chr17:28,532,504...28,545,548
Ensembl chr17:28,532,493...28,545,546
JBrowse link
G Fancf Fanconi anemia, complementation group F affects expression ISO Diclofenac affects the expression of FANCF mRNA CTD PMID:24752500 NCBI chr 7:51,510,325...51,512,015
Ensembl chr 7:51,510,325...51,512,015
JBrowse link
G Fancg Fanconi anemia, complementation group G affects expression ISO Diclofenac affects the expression of FANCG mRNA CTD PMID:24752500 NCBI chr 4:43,002,337...43,010,565
Ensembl chr 4:43,002,343...43,010,506
JBrowse link
G Fancl Fanconi anemia, complementation group L affects expression ISO Diclofenac affects the expression of FANCL mRNA CTD PMID:24752500 NCBI chr11:26,337,084...26,421,883
Ensembl chr11:26,336,135...26,421,876
JBrowse link
G Fancm Fanconi anemia, complementation group M affects expression ISO Diclofenac affects the expression of FANCM mRNA CTD PMID:24752500 NCBI chr12:65,120,884...65,178,616
Ensembl chr12:65,122,377...65,178,832
JBrowse link
G Fas Fas cell surface death receptor affects expression
increases expression
ISO
EXP
Diclofenac affects the expression of FAS mRNA
Diclofenac results in increased expression of FAS mRNA
CTD PMID:24752500 PMID:26934552 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fasl Fas ligand increases expression EXP Diclofenac results in increased expression of FASL mRNA CTD PMID:22285467 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Fasn fatty acid synthase decreases expression ISO Diclofenac results in decreased expression of FASN mRNA CTD PMID:19022234 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
JBrowse link
G Fastk Fas-activated serine/threonine kinase multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of FASTK mRNA CTD PMID:37844793 NCBI chr 5:24,646,036...24,650,280
Ensembl chr 5:24,643,438...24,650,285
JBrowse link
G Fastkd2 FAST kinase domains 2 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of FASTKD2 mRNA CTD PMID:37844793 NCBI chr 1:63,769,758...63,792,544
Ensembl chr 1:63,769,773...63,793,814
JBrowse link
G Fbxo33 F-box protein 33 increases expression EXP Diclofenac results in increased expression of FBXO33 mRNA CTD PMID:35537566 NCBI chr12:59,247,441...59,268,747
Ensembl chr12:59,247,441...59,266,511
JBrowse link
G Fbxo5 F-box protein 5 decreases expression EXP Diclofenac results in decreased expression of FBXO5 mRNA CTD PMID:35537566 NCBI chr10:5,749,155...5,755,465
Ensembl chr10:5,749,160...5,755,600
JBrowse link
G Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide increases expression EXP Diclofenac results in increased expression of FCER1G mRNA CTD PMID:26934552 NCBI chr 1:171,057,141...171,061,918
Ensembl chr 1:171,057,141...171,061,934
JBrowse link
G Fcgr2b Fc receptor, IgG, low affinity IIb decreases expression EXP Diclofenac results in decreased expression of FCGR2B mRNA CTD PMID:35537566 NCBI chr 1:170,786,186...170,804,141
Ensembl chr 1:170,786,186...170,804,116
JBrowse link
G Fcgr3 Fc receptor, IgG, low affinity III increases expression EXP Diclofenac results in increased expression of FCGR3 mRNA CTD PMID:26934552 NCBI chr 1:170,878,738...170,893,477
Ensembl chr 1:170,878,743...170,892,504
JBrowse link
G Fen1 flap structure specific endonuclease 1 increases expression EXP Diclofenac results in increased expression of FEN1 mRNA CTD PMID:26934552 NCBI chr19:10,176,496...10,181,757
Ensembl chr19:10,176,496...10,181,533
JBrowse link
G Fer FER tyrosine kinase affects expression ISO Diclofenac affects the expression of FER mRNA CTD PMID:24752500 NCBI chr17:64,136,945...64,453,515
Ensembl chr17:64,170,057...64,446,491
JBrowse link
G Fermt1 fermitin family member 1 increases expression ISO Diclofenac results in increased expression of FERMT1 mRNA CTD PMID:30723492 NCBI chr 2:132,746,097...132,787,956
Ensembl chr 2:132,746,309...132,787,826
JBrowse link
G Fgb fibrinogen beta chain multiple interactions
increases expression
ISO
EXP
[Diclofenac co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of FGB protein
Diclofenac results in increased expression of FGB mRNA
CTD PMID:25772430 PMID:26934552 NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170
JBrowse link
G Fgf1 fibroblast growth factor 1 decreases expression EXP Diclofenac results in decreased expression of FGF1 mRNA CTD PMID:26934552 NCBI chr18:38,971,725...39,062,532
Ensembl chr18:38,971,726...39,062,525
JBrowse link
G Fgf15 fibroblast growth factor 15 decreases expression EXP Diclofenac results in decreased expression of FGF15 mRNA CTD PMID:38815664 NCBI chr 7:144,450,269...144,454,690
Ensembl chr 7:144,450,268...144,454,690
JBrowse link
G Fgf3 fibroblast growth factor 3 increases expression EXP Diclofenac results in increased expression of FGF3 mRNA CTD PMID:26934552 NCBI chr 7:144,392,349...144,397,085
Ensembl chr 7:144,391,820...144,398,173
JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 affects expression ISO Diclofenac affects the expression of FGFR1 mRNA CTD PMID:24752500 NCBI chr 8:26,008,808...26,067,819
Ensembl chr 8:26,003,670...26,065,734
JBrowse link
G Fgfr1op2 FGFR1 oncogene partner 2 decreases expression EXP Diclofenac results in decreased expression of FGFR1OP2 mRNA CTD PMID:26934552 NCBI chr 6:146,479,401...146,500,696
Ensembl chr 6:146,478,701...146,500,696
JBrowse link
G Fgg fibrinogen gamma chain multiple interactions
decreases expression
ISO [Diclofenac co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of FGG protein; Diclofenac promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of FGG protein]; lipopolysaccharide, E coli O55-B5 promotes the reaction [Diclofenac results in decreased expression of FGG protein] CTD PMID:25772430 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356
JBrowse link
G Fgl1 fibrinogen-like protein 1 increases expression EXP Diclofenac results in increased expression of FGL1 mRNA CTD PMID:26934552 NCBI chr 8:41,644,471...41,671,015
Ensembl chr 8:41,644,471...41,668,193
JBrowse link
G Fmod fibromodulin decreases expression EXP Diclofenac results in decreased expression of FMOD mRNA CTD PMID:26934552 NCBI chr 1:133,964,992...133,976,018
Ensembl chr 1:133,964,992...133,976,015
JBrowse link
G Fn1 fibronectin 1 increases expression EXP Diclofenac results in increased expression of FN1 mRNA; Diclofenac results in increased expression of FN1 protein CTD PMID:26934552 NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359
JBrowse link
G Fnbp1 formin binding protein 1 affects expression ISO Diclofenac affects the expression of FNBP1 mRNA CTD PMID:24752500 NCBI chr 2:30,916,218...31,032,046
Ensembl chr 2:30,916,218...31,032,020
JBrowse link
G Fndc3b fibronectin type III domain containing 3B increases expression EXP Diclofenac results in increased expression of FNDC3B mRNA CTD PMID:26934552 NCBI chr 3:27,470,284...27,765,469
Ensembl chr 3:27,470,311...27,765,456
JBrowse link
G Fnip1 folliculin interacting protein 1 decreases expression EXP Diclofenac results in decreased expression of FNIP1 mRNA CTD PMID:26934552 NCBI chr11:54,328,071...54,409,067
Ensembl chr11:54,329,025...54,409,061
JBrowse link
G Fnip2 folliculin interacting protein 2 decreases expression EXP Diclofenac results in decreased expression of FNIP2 mRNA CTD PMID:26934552 NCBI chr 3:79,363,556...79,475,458
Ensembl chr 3:79,363,281...79,475,103
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression
multiple interactions
affects expression
ISO
EXP
Diclofenac results in increased expression of FOS mRNA
[Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of FOS mRNA
Diclofenac affects the expression of FOS mRNA
CTD PMID:12730611 PMID:24752500 PMID:37844793 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Fosl2 fos-like antigen 2 increases expression EXP Diclofenac results in increased expression of FOSL2 mRNA CTD PMID:26934552 NCBI chr 5:32,292,599...32,315,184
Ensembl chr 5:32,293,145...32,315,186
JBrowse link
G Foxa1 forkhead box A1 affects expression ISO Diclofenac affects the expression of FOXA1 mRNA CTD PMID:24752500 NCBI chr12:57,585,750...57,594,815
Ensembl chr12:57,587,414...57,593,702
JBrowse link
G Foxa3 forkhead box A3 increases expression EXP Diclofenac results in increased expression of FOXA3 mRNA CTD PMID:26934552 NCBI chr 7:18,747,208...18,757,464
Ensembl chr 7:18,747,209...18,757,463
JBrowse link
G Foxo1 forkhead box O1 affects expression ISO Diclofenac affects the expression of FOXO1 mRNA CTD PMID:24752500 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
JBrowse link
G Foxo3 forkhead box O3 affects expression
decreases expression
ISO
EXP
Diclofenac affects the expression of FOXO3 mRNA
Diclofenac results in decreased expression of FOXO3 mRNA
CTD PMID:24752500 PMID:26934552 NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751
JBrowse link
G Fpr2 formyl peptide receptor 2 increases expression EXP Diclofenac results in increased expression of FPR2 mRNA CTD PMID:26934552 NCBI chr17:18,108,086...18,114,214
Ensembl chr17:18,108,086...18,114,214
JBrowse link
G Frat2 frequently rearranged in advanced T cell lymphomas 2 decreases expression EXP Diclofenac results in decreased expression of FRAT2 mRNA CTD PMID:35537566 NCBI chr19:41,834,411...41,836,571
Ensembl chr19:41,834,411...41,836,571
JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 affects expression ISO Diclofenac affects the expression of FRS2 mRNA CTD PMID:24752500 NCBI chr10:116,905,324...116,986,311
Ensembl chr10:116,905,332...116,984,439
JBrowse link
G Ftcd formiminotransferase cyclodeaminase affects expression ISO Diclofenac affects the expression of FTCD mRNA CTD PMID:24752500 NCBI chr10:76,411,482...76,426,172
Ensembl chr10:76,411,482...76,426,172
JBrowse link
G Fyb1 FYN binding protein 1 increases expression EXP Diclofenac results in increased expression of FYB1 mRNA CTD PMID:26934552 NCBI chr15:6,552,280...6,695,089
Ensembl chr15:6,552,334...6,692,794
JBrowse link
G Fzd3 frizzled class receptor 3 affects expression ISO Diclofenac affects the expression of FZD3 mRNA CTD PMID:24752500 NCBI chr14:65,429,890...65,499,912
Ensembl chr14:65,429,898...65,499,912
JBrowse link
G Fzd4 frizzled class receptor 4 affects expression ISO Diclofenac affects the expression of FZD4 mRNA CTD PMID:24752500 NCBI chr 7:89,053,574...89,062,341
Ensembl chr 7:89,053,563...89,062,342
JBrowse link
G Fzd5 frizzled class receptor 5 affects expression ISO Diclofenac affects the expression of FZD5 mRNA CTD PMID:24752500 NCBI chr 1:64,769,717...64,776,907
Ensembl chr 1:64,769,717...64,776,910
JBrowse link
G Fzd6 frizzled class receptor 6 affects expression ISO Diclofenac affects the expression of FZD6 mRNA CTD PMID:24752500 NCBI chr15:38,869,673...38,901,587
Ensembl chr15:38,869,429...38,901,583
JBrowse link
G Fzd7 frizzled class receptor 7 affects expression ISO Diclofenac affects the expression of FZD7 mRNA CTD PMID:24752500 NCBI chr 1:59,521,306...59,526,114
Ensembl chr 1:59,521,583...59,526,114
JBrowse link
G G6pd2 glucose-6-phosphate dehydrogenase 2 multiple interactions EXP [Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in increased activity of G6PD2 protein; [Sodium Selenite co-treated with Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in increased activity of G6PD2 protein CTD PMID:38945390 NCBI chr 5:61,966,186...61,967,820
Ensembl chr 5:61,966,159...61,968,506
JBrowse link
G Gab1 growth factor receptor bound protein 2-associated protein 1 affects expression ISO Diclofenac affects the expression of GAB1 mRNA CTD PMID:24752500 NCBI chr 8:81,491,060...81,607,151
Ensembl chr 8:81,491,063...81,607,148
JBrowse link
G Gab2 growth factor receptor bound protein 2-associated protein 2 affects expression ISO Diclofenac affects the expression of GAB2 mRNA CTD PMID:24752500 NCBI chr 7:96,730,958...96,958,158
Ensembl chr 7:96,730,793...96,958,153
JBrowse link
G Gabra5 gamma-aminobutyric acid type A receptor subunit alpha 5 decreases expression EXP Diclofenac results in decreased expression of GABRA5 mRNA CTD PMID:26934552 NCBI chr 7:57,057,417...57,240,808
Ensembl chr 7:57,057,420...57,159,807
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha increases expression
decreases expression
affects expression
ISO
EXP
Diclofenac results in increased expression of GADD45A mRNA
Diclofenac results in decreased expression of GADD45A mRNA
Diclofenac affects the expression of GADD45A mRNA
CTD PMID:18172885 PMID:19022234 PMID:24752500 PMID:26934552 PMID:35537566 NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible 45 gamma increases expression EXP Diclofenac results in increased expression of GADD45G mRNA CTD PMID:26934552 NCBI chr13:52,000,711...52,002,511
Ensembl chr13:52,000,714...52,002,504
JBrowse link
G Galnt3 polypeptide N-acetylgalactosaminyltransferase 3 increases expression ISO Diclofenac results in increased expression of GALNT3 mRNA CTD PMID:30723492 NCBI chr 2:65,913,110...65,955,217
Ensembl chr 2:65,913,110...65,955,338
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions EXP [Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in decreased expression of GAPDH mRNA; Sodium Selenite promotes the reaction [[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in decreased expression of GAPDH mRNA] CTD PMID:38945390 NCBI chr 6:125,138,812...125,143,450
Ensembl chr 6:125,138,678...125,143,430
JBrowse link
G Gars1 glycyl-tRNA synthetase 1 affects expression
decreases expression
ISO
EXP
Diclofenac affects the expression of GARS1 mRNA
Diclofenac results in decreased expression of GARS1 mRNA
CTD PMID:24752500 PMID:35537566 NCBI chr 6:55,014,986...55,056,489
Ensembl chr 6:55,014,992...55,056,485
JBrowse link
G Gart phosphoribosylglycinamide formyltransferase affects expression ISO Diclofenac affects the expression of GART mRNA CTD PMID:24752500 NCBI chr16:91,418,283...91,444,505
Ensembl chr16:91,418,074...91,443,840
JBrowse link
G Gas1 growth arrest specific 1 decreases expression EXP Diclofenac results in decreased expression of GAS1 mRNA CTD PMID:26934552 NCBI chr13:60,322,219...60,325,179
Ensembl chr13:60,322,219...60,325,179
JBrowse link
G Gata4 GATA binding protein 4 affects expression ISO Diclofenac affects the expression of GATA4 mRNA CTD PMID:24752500 NCBI chr14:63,436,363...63,509,161
Ensembl chr14:63,436,371...63,509,141
JBrowse link
G Gata6 GATA binding protein 6 increases expression EXP Diclofenac results in increased expression of GATA6 mRNA CTD PMID:26934552 NCBI chr18:11,052,510...11,085,636
Ensembl chr18:11,052,064...11,085,635
JBrowse link
G Gbp2b guanylate binding protein 2b decreases expression ISO Diclofenac results in decreased expression of GBP1 mRNA CTD PMID:19192274 NCBI chr 3:142,300,577...142,324,940
Ensembl chr 3:142,300,608...142,324,940
JBrowse link
G Gbp3 guanylate binding protein 3 increases expression EXP Diclofenac results in increased expression of GBP3 mRNA CTD PMID:26934552 NCBI chr 3:142,265,781...142,278,974
Ensembl chr 3:142,265,787...142,278,970
JBrowse link
G Gc vitamin D binding protein multiple interactions ISO [Diclofenac co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of GC protein CTD PMID:25772430 NCBI chr 5:89,565,370...89,605,757
Ensembl chr 5:89,565,381...89,605,757
JBrowse link
G Gck glucokinase affects expression EXP Diclofenac affects the expression of GCK mRNA CTD PMID:26934552 NCBI chr11:5,850,816...5,900,081
Ensembl chr11:5,850,820...5,900,081
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression
affects expression
affects response to substance
ISO Diclofenac results in decreased expression of GCLC mRNA
Diclofenac affects the expression of GCLC mRNA
GCLC protein affects the susceptibility to Diclofenac
CTD PMID:17202759 PMID:19481141 PMID:24752500 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit affects expression ISO Diclofenac affects the expression of GCLM mRNA CTD PMID:24752500 NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression EXP
ISO
Diclofenac results in increased expression of GDF15 mRNA
Diclofenac results in increased expression of GDF15 protein
CTD PMID:15555568 PMID:18076062 NCBI chr 8:71,082,043...71,085,106
Ensembl chr 8:71,082,043...71,085,106
JBrowse link
G Gdf6 growth differentiation factor 6 increases expression ISO Diclofenac results in increased expression of GDF6 mRNA CTD PMID:30723492 NCBI chr 4:9,844,372...9,862,345
Ensembl chr 4:9,844,372...9,862,345
JBrowse link
G Gdf9 growth differentiation factor 9 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of GDF9 mRNA CTD PMID:37844793 NCBI chr11:53,321,773...53,328,731
Ensembl chr11:53,321,850...53,328,731
JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 increases expression EXP Diclofenac results in increased expression of GFPT1 mRNA CTD PMID:26934552 NCBI chr 6:87,019,828...87,069,189
Ensembl chr 6:87,019,828...87,069,179
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Diclofenac] results in increased activity of GGT1 protein CTD PMID:23939143 NCBI chr10:75,396,910...75,422,027
Ensembl chr10:75,397,438...75,422,034
JBrowse link
G Ghr growth hormone receptor affects expression EXP Diclofenac affects the expression of GHR protein CTD PMID:26934552 NCBI chr15:3,347,237...3,612,834
Ensembl chr15:3,347,242...3,612,974
JBrowse link
G Git2 GIT ArfGAP 2 affects expression ISO Diclofenac affects the expression of GIT2 mRNA CTD PMID:24752500 NCBI chr 5:114,865,469...114,912,647
Ensembl chr 5:114,865,468...114,913,578
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression EXP Diclofenac results in increased expression of GJA1 mRNA CTD PMID:26934552 PMID:35537566 NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609
JBrowse link
G Gja3 gap junction protein, alpha 3 increases expression EXP Diclofenac results in increased expression of GJA3 mRNA CTD PMID:26934552 NCBI chr14:57,271,917...57,295,487
Ensembl chr14:57,271,917...57,295,557
JBrowse link
G Gldc glycine decarboxylase affects expression ISO Diclofenac affects the expression of GLDC mRNA CTD PMID:24752500 NCBI chr19:30,075,847...30,152,829
Ensembl chr19:30,075,847...30,152,829
JBrowse link
G Glrp1 glutamine repeat protein 1 decreases expression EXP Diclofenac results in decreased expression of GLRP1 mRNA CTD PMID:35537566 NCBI chr 1:88,427,593...88,437,788
Ensembl chr 1:88,427,593...88,437,788
JBrowse link
G Glyctk glycerate kinase affects expression ISO Diclofenac affects the expression of GLYCTK mRNA CTD PMID:24752500 NCBI chr 9:106,030,058...106,037,353
Ensembl chr 9:106,030,056...106,035,337
JBrowse link
G Gna13 guanine nucleotide binding protein, alpha 13 affects expression ISO Diclofenac affects the expression of GNA13 mRNA CTD PMID:24752500 NCBI chr11:109,253,620...109,292,195
Ensembl chr11:109,253,657...109,292,195
JBrowse link
G Gnaq guanine nucleotide binding protein, alpha q polypeptide affects expression ISO Diclofenac affects the expression of GNAQ mRNA CTD PMID:24752500 NCBI chr19:16,110,048...16,365,884
Ensembl chr19:16,110,195...16,364,827
JBrowse link
G Gnas GNAS complex locus affects expression ISO Diclofenac affects the expression of GNAS mRNA CTD PMID:24752500 NCBI chr 2:174,126,113...174,188,537
Ensembl chr 2:174,126,113...174,188,537
JBrowse link
G Gnat1 G protein subunit alpha transducin 1 increases expression EXP Diclofenac results in increased expression of GNAT1 mRNA CTD PMID:26934552 NCBI chr 9:107,551,636...107,556,833
Ensembl chr 9:107,551,673...107,556,911
JBrowse link
G Gnb5 guanine nucleotide binding protein (G protein), beta 5 affects expression ISO Diclofenac affects the expression of GNB5 mRNA CTD PMID:24752500 NCBI chr 9:75,213,570...75,253,205
Ensembl chr 9:75,213,570...75,253,158
JBrowse link
G Gng4 guanine nucleotide binding protein (G protein), gamma 4 affects expression ISO Diclofenac affects the expression of GNG4 mRNA CTD PMID:24752500 NCBI chr13:13,958,644...14,002,480
Ensembl chr13:13,958,644...14,002,481
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1, soluble affects expression
increases secretion
ISO Diclofenac affects the expression of GOT1 mRNA
Diclofenac results in increased secretion of GOT1 protein
CTD PMID:24752500 PMID:36442613 NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 (soluble) multiple interactions ISO Diclofenac inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of GPD1 protein] CTD PMID:25772430 NCBI chr15:99,615,468...99,622,895
Ensembl chr15:99,615,396...99,622,886
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 affects expression ISO Diclofenac affects the expression of GPLD1 mRNA CTD PMID:24752500 NCBI chr13:25,127,135...25,175,919
Ensembl chr13:25,127,135...25,176,484
JBrowse link
G Gpr176 G protein-coupled receptor 176 decreases expression EXP Diclofenac results in decreased expression of GPR176 mRNA CTD PMID:35537566 NCBI chr 2:118,107,577...118,205,022
Ensembl chr 2:118,107,591...118,203,900
JBrowse link
G Gpr20 G protein-coupled receptor 20 decreases expression ISO Diclofenac results in decreased expression of GPR20 mRNA CTD PMID:30723492 NCBI chr15:73,560,346...73,579,354
Ensembl chr15:73,566,453...73,579,354
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions
increases secretion
increases expression
increases activity
ISO
EXP
[lipopolysaccharide, E coli O55-B5 co-treated with Diclofenac] results in increased activity of GPT protein; Diclofenac promotes the reaction [endotoxin, Escherichia coli results in increased activity of GPT protein]; Heparin inhibits the reaction [Diclofenac promotes the reaction [endotoxin, Escherichia coli results in increased activity of GPT protein]]
Diclofenac results in increased secretion of GPT protein
Diclofenac results in increased expression of GPT protein
Diclofenac results in increased activity of GPT protein
[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in increased expression of GPT protein; eritoran inhibits the reaction [Diclofenac results in increased expression of GPT protein]; Sodium Selenite inhibits the reaction [[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in increased expression of GPT protein]
CTD PMID:23939143 PMID:24747151 PMID:26934552 PMID:27671914 PMID:30925002 More... NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
G Gpt2 glutamic pyruvate transaminase (alanine aminotransferase) 2 decreases expression EXP Diclofenac results in decreased expression of GPT2 mRNA CTD PMID:35537566 NCBI chr 8:86,219,090...86,255,531
Ensembl chr 8:86,219,205...86,254,189
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression
multiple interactions
ISO
EXP
Diclofenac results in increased expression of GPX1 mRNA; Diclofenac results in increased expression of GPX1 protein
[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in decreased expression of GPX1 mRNA; Sodium Selenite promotes the reaction [[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in decreased expression of GPX1 mRNA]
CTD PMID:25772430 PMID:29027214 PMID:38945390 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Gpx2 glutathione peroxidase 2 affects expression ISO Diclofenac affects the expression of GPX2 mRNA CTD PMID:24752500 NCBI chr12:76,839,109...76,842,328
Ensembl chr12:76,839,107...76,842,273
JBrowse link
G Gpx3 glutathione peroxidase 3 multiple interactions EXP [Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in increased expression of GPX3 mRNA; Sodium Selenite promotes the reaction [[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in increased expression of GPX3 mRNA] CTD PMID:38945390 NCBI chr11:54,793,680...54,801,213
Ensembl chr11:54,793,279...54,801,203
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions EXP [Sodium Selenite co-treated with Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in decreased expression of GPX4 mRNA CTD PMID:38945390 NCBI chr10:79,883,000...79,892,273
Ensembl chr10:79,883,000...79,892,273
JBrowse link
G Grb10 growth factor receptor bound protein 10 affects expression ISO Diclofenac affects the expression of GRB10 mRNA CTD PMID:24752500 NCBI chr11:11,880,499...11,987,428
Ensembl chr11:11,880,508...11,988,683
JBrowse link
G Grid2 glutamate receptor, ionotropic, delta 2 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in increased expression of GRID2 mRNA CTD PMID:37844793 NCBI chr 6:63,230,118...64,681,305
Ensembl chr 6:63,232,860...64,681,307
JBrowse link
G Grm7 glutamate receptor, metabotropic 7 increases expression EXP Diclofenac results in increased expression of GRM7 mRNA CTD PMID:26934552 NCBI chr 6:110,622,304...111,544,191
Ensembl chr 6:110,622,542...111,544,191
JBrowse link
G Gsdmd gasdermin D multiple interactions
increases cleavage
ISO diacerein inhibits the reaction [Diclofenac results in increased cleavage of GSDMD protein] CTD PMID:38582345 NCBI chr15:75,733,990...75,739,257
Ensembl chr15:75,734,176...75,739,257
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta affects expression ISO Diclofenac affects the expression of GSK3B mRNA CTD PMID:24752500 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
JBrowse link
G Gsn gelsolin decreases expression EXP Diclofenac results in decreased expression of GSN mRNA CTD PMID:26934552 NCBI chr 2:35,146,371...35,197,914
Ensembl chr 2:35,146,392...35,197,904
JBrowse link
G Gsta1 glutathione S-transferase, alpha 1 (Ya) multiple interactions
increases expression
ISO [Diclofenac co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of GSTA5 protein
Diclofenac results in increased expression of GSTA5 protein
CTD PMID:25772430 NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966
JBrowse link
G Gsta3 glutathione S-transferase, alpha 3 decreases activity ISO Diclofenac results in decreased activity of GSTA3 protein CTD PMID:27183920 NCBI chr 1:21,310,837...21,335,885
Ensembl chr 1:21,310,813...21,335,885
JBrowse link
G Gsta4 glutathione S-transferase, alpha 4 decreases expression EXP Diclofenac results in decreased expression of GSTA4 mRNA CTD PMID:26934552 NCBI chr 9:78,099,248...78,116,631
Ensembl chr 9:78,090,056...78,116,631
JBrowse link
G Gstm1 glutathione S-transferase, mu 1 decreases activity
decreases expression
ISO
EXP
Diclofenac results in decreased activity of GSTM1 protein
Diclofenac results in decreased expression of GSTM1 mRNA
CTD PMID:26934552 PMID:27183920 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289
JBrowse link
G Gstm2 glutathione S-transferase, mu 2 decreases activity ISO Diclofenac results in decreased activity of GSTM2 protein CTD PMID:27183920 NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769
JBrowse link
G Gstm4 glutathione S-transferase, mu 4 affects activity ISO Diclofenac affects the activity of GSTM4 protein CTD PMID:27183920 NCBI chr 3:107,937,887...107,952,495
Ensembl chr 3:107,947,724...107,952,210
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression EXP Diclofenac results in increased expression of GSTM3 mRNA CTD PMID:26934552 NCBI chr 3:107,803,240...107,806,002
Ensembl chr 3:107,803,137...107,806,002
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 multiple interactions
affects activity
affects metabolic processing
ISO [[CYP2C9 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased hydroxylation of Diclofenac] which results in increased abundance of 4'-hydroxydiclofenac; [[CYP2D6 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased hydroxylation of Diclofenac] which results in increased abundance of 4'-hydroxydiclofenac; [[CYP3A4 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased hydroxylation of Diclofenac] which results in increased abundance of 5-hydroxydiclofenac; [CYP2C9 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased hydroxylation of Diclofenac; [CYP2C9 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased metabolism of Diclofenac; [CYP2D6 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased hydroxylation of Diclofenac; [CYP3A4 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of Diclofenac; [CYP3A4 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased hydroxylation of Diclofenac
Diclofenac affects the activity of GSTP1 protein
GSTP1 protein affects the metabolism of Diclofenac metabolite; GSTP1 protein polymorphism affects the metabolism of Diclofenac metabolite
CTD PMID:24185126 PMID:24246759 PMID:27183920 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G Gstt1 glutathione S-transferase, theta 1 affects expression
affects activity
ISO Diclofenac affects the expression of GSTT1 mRNA
Diclofenac affects the activity of GSTT1 protein
CTD PMID:24752500 PMID:27183920 NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418
JBrowse link
G Gstt3 glutathione S-transferase, theta 3 decreases expression EXP Diclofenac results in decreased expression of GSTT3 mRNA CTD PMID:26934552 NCBI chr10:75,609,951...75,617,256
Ensembl chr10:75,609,949...75,617,248
JBrowse link
G Gtf2h4 general transcription factor II H, polypeptide 4 affects expression ISO Diclofenac affects the expression of GTF2H4 mRNA CTD PMID:24752500 NCBI chr17:35,978,624...35,984,607
Ensembl chr17:35,978,622...35,984,631
JBrowse link
G Gtf2h5 general transcription factor IIH, polypeptide 5 affects expression ISO Diclofenac affects the expression of GTF2H5 mRNA CTD PMID:24752500 NCBI chr17:6,130,103...6,135,763
Ensembl chr17:6,130,061...6,136,792
JBrowse link
G Gtpbp2 GTP binding protein 2 decreases expression EXP Diclofenac results in decreased expression of GTPBP2 mRNA CTD PMID:35537566 NCBI chr17:46,470,153...46,480,294
Ensembl chr17:46,471,958...46,480,296
JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 decreases expression ISO Diclofenac results in decreased expression of RT1-BB mRNA CTD PMID:17202759 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393
JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta affects expression ISO Diclofenac affects the expression of HLA-DRB1 mRNA CTD PMID:25811541 NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648
JBrowse link
G H2ax H2A.X variant histone increases expression ISO Diclofenac results in increased expression of H2AX protein CTD PMID:32087850 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374
JBrowse link
G H2bc4 H2B clustered histone 4 decreases expression EXP Diclofenac results in decreased expression of H2BC21 mRNA CTD PMID:26934552 NCBI chr13:23,868,182...23,876,805
Ensembl chr13:23,868,182...23,876,891
JBrowse link
G Hamp hepcidin antimicrobial peptide affects expression
decreases secretion
EXP Diclofenac affects the expression of HAMP mRNA
Diclofenac results in decreased secretion of HAMP protein
CTD PMID:24038040 PMID:26934552 NCBI chr 7:30,641,793...30,643,454
Ensembl chr 7:30,641,793...30,643,457
JBrowse link
G Hamp2 hepcidin antimicrobial peptide 2 decreases expression EXP Diclofenac results in decreased expression of HAMP2 mRNA CTD PMID:26934552 NCBI chr 7:30,621,797...30,623,606
Ensembl chr 7:30,621,797...30,624,106
JBrowse link
G Hat1 histone aminotransferase 1 affects expression ISO Diclofenac affects the expression of HAT1 mRNA CTD PMID:24752500 NCBI chr 2:71,219,604...71,271,966
Ensembl chr 2:71,219,302...71,271,966
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression
multiple interactions
increases secretion
ISO Diclofenac results in increased expression of HAVCR1 mRNA
diacerein inhibits the reaction [Diclofenac results in increased secretion of HAVCR1 protein]
CTD PMID:23506792 PMID:38582345 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 increases expression ISO Diclofenac results in increased expression of HBA-A2 protein CTD PMID:14565772 NCBI chr11:32,246,492...32,247,310
Ensembl chr11:32,246,489...32,247,298
JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain increases expression ISO Diclofenac results in increased expression of HBB protein CTD PMID:14565772
G Hbegf heparin-binding EGF-like growth factor affects expression
decreases expression
increases expression
ISO
EXP
Diclofenac affects the expression of HBEGF mRNA
Diclofenac results in decreased expression of HBEGF mRNA
Diclofenac results in increased expression of HBEGF mRNA
CTD PMID:24752500 PMID:26934552 PMID:35537566 NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858
JBrowse link
G Hck hemopoietic cell kinase increases expression EXP Diclofenac results in increased expression of HCK mRNA CTD PMID:26934552 NCBI chr 2:152,950,388...152,993,361
Ensembl chr 2:152,950,388...152,993,361
JBrowse link
G Herc6 hect domain and RLD 6 decreases expression
increases expression
ISO
EXP
Diclofenac results in decreased expression of HERC6 mRNA
Diclofenac results in increased expression of HERC6 mRNA
CTD PMID:19192274 PMID:26934552 NCBI chr 6:57,557,977...57,642,121
Ensembl chr 6:57,557,985...57,641,617
JBrowse link
G Herpud1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 affects expression
decreases expression
ISO
EXP
Diclofenac affects the expression of HERPUD1 mRNA
Diclofenac results in decreased expression of HERPUD1 mRNA
CTD PMID:24752500 PMID:26934552 PMID:35537566 NCBI chr 8:95,113,057...95,121,999
Ensembl chr 8:95,113,066...95,122,005
JBrowse link
G Hes6 hairy and enhancer of split 6 decreases expression EXP Diclofenac results in decreased expression of HES6 mRNA CTD PMID:26934552 NCBI chr 1:91,339,204...91,342,901
Ensembl chr 1:91,339,205...91,341,760
JBrowse link
G Hhex hematopoietically expressed homeobox decreases expression EXP Diclofenac results in decreased expression of HHEX mRNA CTD PMID:26934552 NCBI chr19:37,423,289...37,429,179
Ensembl chr19:37,423,258...37,429,179
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit decreases expression ISO Diclofenac results in decreased expression of HIF1A protein CTD PMID:12912967 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Hk1 hexokinase 1 increases expression EXP Diclofenac results in increased expression of HK1 mRNA CTD PMID:26934552 NCBI chr10:62,104,634...62,215,699
Ensembl chr10:62,104,634...62,215,687
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions
increases expression
affects expression
ISO
EXP
Diclofenac promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of HMGB1 protein]
Diclofenac results in increased expression of HMGB1 mRNA; Diclofenac results in increased expression of HMGB1 protein
Diclofenac affects the expression of HMGB1 mRNA
CTD PMID:23939143 PMID:24747151 PMID:24752500 PMID:26934552 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase multiple interactions EXP [Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in increased expression of HMGCR mRNA; Sodium Selenite inhibits the reaction [[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in increased expression of HMGCR mRNA] CTD PMID:38945390 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 decreases expression EXP Diclofenac results in decreased expression of HMGCS2 mRNA CTD PMID:26934552 NCBI chr 3:98,187,747...98,218,054
Ensembl chr 3:98,187,751...98,218,054
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
decreases expression
increases expression
affects expression
ISO
EXP
1-aminobenzotriazole inhibits the reaction [[Diclofenac co-treated with Buthionine Sulfoximine] results in increased expression of HMOX1 mRNA]; Buthionine Sulfoximine promotes the reaction [Diclofenac results in increased expression of HMOX1 mRNA]
Diclofenac results in decreased expression of HMOX1 protein
Diclofenac results in increased expression of HMOX1 mRNA; Diclofenac results in increased expression of HMOX1 protein
[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in increased expression of HMOX1 mRNA; [Sodium Selenite co-treated with Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in increased expression of HMOX1 mRNA; Acetylcysteine inhibits the reaction [Diclofenac results in increased expression of HMOX1 protein]; Buthionine Sulfoximine promotes the reaction [Diclofenac results in increased expression of HMOX1 protein]; Diclofenac promotes the reaction [Buthionine Sulfoximine results in increased expression of HMOX1 protein]
Acetylcysteine inhibits the reaction [Diclofenac results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [Diclofenac results in increased expression of HMOX1 mRNA]; diacerein inhibits the reaction [Diclofenac results in decreased expression of HMOX1 protein]; Diclofenac promotes the reaction [Poly I-C results in increased expression of HMOX1 mRNA]; Ketoconazole inhibits the reaction [Diclofenac results in increased expression of HMOX1 mRNA]; Sulfaphenazole inhibits the reaction [Diclofenac results in increased expression of HMOX1 mRNA]; Tranylcypromine inhibits the reaction [Diclofenac results in increased expression of HMOX1 mRNA]
Diclofenac affects the expression of HMOX1 protein
CTD PMID:12763371 PMID:18172885 PMID:18227147 PMID:19022234 PMID:19952508 More... NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hmx3 H6 homeobox 3 decreases expression EXP Diclofenac results in decreased expression of HMX3 mRNA CTD PMID:35537566 NCBI chr 7:131,143,263...131,147,756
Ensembl chr 7:131,144,596...131,146,654
JBrowse link
G Hnf1a HNF1 homeobox A affects expression ISO Diclofenac affects the expression of HNF1A mRNA CTD PMID:24752500 NCBI chr 5:115,087,039...115,109,121
Ensembl chr 5:115,087,039...115,109,153
JBrowse link
G Hnf4a hepatic nuclear factor 4, alpha decreases expression ISO Diclofenac results in decreased expression of HNF4A mRNA CTD PMID:19022234 NCBI chr 2:163,348,731...163,414,827
Ensembl chr 2:163,348,728...163,414,830
JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D affects expression ISO Diclofenac affects the expression of HNRNPD mRNA CTD PMID:24752500 NCBI chr 5:100,103,794...100,126,926
Ensembl chr 5:100,103,794...100,126,797
JBrowse link
G Hoatz HOATZ cilia and flagella associated protein multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of HOATZ mRNA CTD PMID:37844793 NCBI chr 9:50,992,610...51,017,183
Ensembl chr 9:50,992,415...51,013,378
JBrowse link
G Hp haptoglobin increases expression
decreases expression
EXP Diclofenac results in increased expression of HP mRNA
Diclofenac results in decreased expression of HP mRNA
CTD PMID:26934552 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804
JBrowse link
G Hpgd hydroxyprostaglandin dehydrogenase 15 (NAD) increases activity
multiple interactions
increases expression
ISO Diclofenac results in increased activity of HPGD protein
[Diclofenac co-treated with NAD] binds to HPGD protein
Diclofenac results in increased expression of HPGD mRNA
CTD PMID:19501039 PMID:25526675 NCBI chr 8:56,747,587...56,774,081
Ensembl chr 8:56,747,620...56,774,078
JBrowse link
G Hras Harvey rat sarcoma virus oncogene affects expression ISO Diclofenac affects the expression of HRAS mRNA CTD PMID:24752500 NCBI chr 7:140,770,839...140,773,938
Ensembl chr 7:140,769,018...140,773,918
JBrowse link
G Hs3st3b1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 decreases expression EXP Diclofenac results in decreased expression of HS3ST3B1 mRNA CTD PMID:35537566 NCBI chr11:63,775,519...63,813,110
Ensembl chr11:63,776,618...63,813,116
JBrowse link
G Hs6st2 heparan sulfate 6-O-sulfotransferase 2 increases expression EXP Diclofenac results in increased expression of HS6ST2 mRNA CTD PMID:26934552 NCBI chr  X:50,476,084...50,770,643
Ensembl chr  X:50,476,089...50,770,733
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression EXP Diclofenac results in decreased expression of HSD3B2 mRNA CTD PMID:26934552 NCBI chr 3:98,749,672...98,767,110
Ensembl chr 3:98,759,510...98,767,110
JBrowse link
G Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 increases expression
decreases expression
EXP Diclofenac results in increased expression of HSD3B5 mRNA
Diclofenac results in decreased expression of HSD3B5 mRNA
CTD PMID:26934552 NCBI chr 3:98,525,952...98,552,850
Ensembl chr 3:98,525,950...98,537,568
JBrowse link
G Hsf1 heat shock factor 1 increases activity ISO Diclofenac results in increased activity of HSF1 protein CTD PMID:34170685 NCBI chr15:76,361,562...76,385,355
Ensembl chr15:76,361,622...76,386,113
JBrowse link
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 multiple interactions ISO Diclofenac inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of HSP90AA1 mRNA] CTD PMID:23939143 NCBI chr12:110,657,470...110,662,829
Ensembl chr12:110,657,039...110,669,162
JBrowse link
G Hspa1a heat shock protein 1A multiple interactions
affects expression
increases expression
ISO
EXP
Diclofenac inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of HSPA1A mRNA]
[Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of HSPA1A mRNA
Diclofenac affects the expression of HSPA1A mRNA
Diclofenac results in increased expression of HSPA1A mRNA
CTD PMID:19022234 PMID:23939143 PMID:25014874 PMID:26934552 PMID:37844793 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132
JBrowse link
G Hspa1b heat shock protein 1B increases expression
multiple interactions
EXP Diclofenac results in increased expression of HSPA1B mRNA
[Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of HSPA1B mRNA
CTD PMID:26934552 PMID:37844793 NCBI chr17:35,175,405...35,178,214
Ensembl chr17:35,175,412...35,178,214
JBrowse link
G Hspa5 heat shock protein 5 increases expression
multiple interactions
ISO Diclofenac results in increased expression of HSPA5 mRNA
[Diclofenac co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of HSPA5 protein
CTD PMID:25014874 PMID:25772430 PMID:27313093 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
JBrowse link
G Hspa8 heat shock protein 8 multiple interactions
increases expression
ISO
EXP
Diclofenac inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of HSPA8 mRNA]
Diclofenac results in increased expression of HSPA8 mRNA
CTD PMID:23939143 PMID:26934552 NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383
JBrowse link
G Hspb1 heat shock protein 1 decreases expression EXP Diclofenac results in decreased expression of HSPB1 mRNA CTD PMID:26934552 NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417
JBrowse link
G Hspb8 heat shock protein 8 increases expression EXP Diclofenac results in increased expression of HSPB8 mRNA CTD PMID:26934552 NCBI chr 5:116,546,550...116,560,923
Ensembl chr 5:116,546,550...116,560,923
JBrowse link
G Iars1 isoleucyl-tRNA synthetase 1 decreases expression EXP Diclofenac results in decreased expression of IARS1 mRNA CTD PMID:35537566 NCBI chr13:49,835,606...49,887,743
Ensembl chr13:49,835,576...49,887,743
JBrowse link
G Ibtk inhibitor of Bruton agammaglobulinemia tyrosine kinase increases expression EXP Diclofenac results in increased expression of IBTK mRNA CTD PMID:26934552 NCBI chr 9:85,569,412...85,632,756
Ensembl chr 9:85,569,413...85,631,387
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
decreases expression
increases expression
affects expression
ISO
EXP
Amlodipine inhibits the reaction [Diclofenac results in decreased expression of ICAM1 protein]
Diclofenac results in decreased expression of ICAM1 mRNA
Diclofenac results in increased expression of ICAM1 mRNA
Diclofenac affects the expression of ICAM1 mRNA
CTD PMID:14716214 PMID:18460984 PMID:24752500 PMID:26934552 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression EXP Diclofenac results in increased expression of ID2 mRNA CTD PMID:26934552 NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139
JBrowse link
G Id3 inhibitor of DNA binding 3 increases expression EXP Diclofenac results in increased expression of ID3 mRNA CTD PMID:26934552 NCBI chr 4:135,871,133...135,872,703
Ensembl chr 4:135,870,808...135,873,066
JBrowse link
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial decreases expression EXP Diclofenac results in decreased expression of IDH2 mRNA CTD PMID:26934552 NCBI chr 7:79,744,594...79,768,356
Ensembl chr 7:79,744,594...79,765,140
JBrowse link
G Ier3 immediate early response 3 increases expression EXP Diclofenac results in increased expression of IER3 mRNA CTD PMID:26934552 NCBI chr17:36,132,605...36,133,803
Ensembl chr17:36,132,576...36,133,815
JBrowse link
G Ifi211 interferon activated gene 211 increases expression EXP Diclofenac results in increased expression of MNDA mRNA CTD PMID:26934552 NCBI chr 1:173,723,907...173,740,650
Ensembl chr 1:173,723,911...173,740,612
JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 decreases expression ISO Diclofenac results in decreased expression of IFI27 mRNA CTD PMID:19192274 NCBI chr12:103,400,448...103,406,504
Ensembl chr12:103,400,470...103,406,498
JBrowse link
G Ifi35 interferon-induced protein 35 decreases expression ISO Diclofenac results in decreased expression of IFI35 mRNA CTD PMID:19192274 NCBI chr11:101,339,238...101,349,527
Ensembl chr11:101,339,233...101,349,524
JBrowse link
G Ifi44 interferon-induced protein 44 decreases expression ISO
EXP
Diclofenac results in decreased expression of IFI44 mRNA CTD PMID:19192274 PMID:35537566 NCBI chr 3:151,436,559...151,455,580
Ensembl chr 3:151,436,559...151,455,597
JBrowse link
G Ifi44l interferon-induced protein 44 like decreases expression ISO Diclofenac results in decreased expression of IFI44L mRNA CTD PMID:19192274 NCBI chr 3:151,464,374...151,468,528
Ensembl chr 3:151,464,374...151,468,529
JBrowse link
G Ifi47 interferon gamma inducible protein 47 increases expression EXP Diclofenac results in increased expression of IFI47 mRNA CTD PMID:26934552 NCBI chr11:48,967,414...48,987,814
Ensembl chr11:48,967,414...48,987,801
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 decreases expression ISO Diclofenac results in decreased expression of IFIH1 mRNA CTD PMID:19192274 NCBI chr 2:62,426,137...62,476,599
Ensembl chr 2:62,426,142...62,476,599
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression ISO Diclofenac results in decreased expression of IFIT3 mRNA CTD PMID:19192274 NCBI chr19:34,560,519...34,566,382
Ensembl chr19:34,560,931...34,566,131
JBrowse link
G Ifitm2 interferon induced transmembrane protein 2 increases expression EXP Diclofenac results in increased expression of IFITM2 mRNA CTD PMID:26934552 NCBI chr 7:140,534,750...140,539,602
Ensembl chr 7:140,534,750...140,535,900
JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 increases expression EXP Diclofenac results in increased expression of IFITM3 mRNA CTD PMID:26934552 NCBI chr 7:140,589,503...140,590,657
Ensembl chr 7:140,589,499...140,590,683
JBrowse link
G Ifitm6 interferon induced transmembrane protein 6 increases expression EXP Diclofenac results in increased expression of IFITM6 mRNA CTD PMID:26934552 NCBI chr 7:140,595,725...140,596,805
Ensembl chr 7:140,595,612...140,597,837
JBrowse link
G Ifna9 interferon alpha 9 increases expression EXP Diclofenac results in increased expression of IFNA9 mRNA CTD PMID:26934552 NCBI chr 4:88,510,050...88,510,622
Ensembl chr 4:88,510,050...88,510,622
JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
ISO
EXP
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; Diclofenac inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IFNG protein]; Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in decreased expression of NFKBIA protein]; Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]; Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 protein]; Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein]; Diclofenac promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IFNG mRNA]; Diclofenac promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IFNG protein]; RELA mutant form inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; SN50 peptide inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[Diclofenac co-treated with IFNG protein] results in increased phosphorylation of STAT1 protein]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[TNF protein co-treated with IFNG protein] promotes the reaction [Diclofenac results in increased activity of CASP3 protein]]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [IFNG protein promotes the reaction [Diclofenac results in increased activity of CASP3 protein]]; 2-aminoethoxydiphenyl borate inhibits the reaction [[Diclofenac co-treated with IFNG protein] results in increased phosphorylation of STAT1 protein]; 2-aminoethoxydiphenyl borate inhibits the reaction [[TNF protein co-treated with IFNG protein] promotes the reaction [Diclofenac results in increased activity of CASP3 protein]]; [Diclofenac co-treated with IFNG protein] results in increased phosphorylation of STAT1 protein; [TNF protein co-treated with IFNG protein] promotes the reaction [Diclofenac affects the abundance of Calcium]; [TNF protein co-treated with IFNG protein] promotes the reaction [Diclofenac results in increased activity of CASP3 protein]; Calcium promotes the reaction [[Diclofenac co-treated with IFNG protein] results in increased phosphorylation of STAT1 protein]; IFNG protein promotes the reaction [Diclofenac results in increased activity of CASP3 protein]; pyrazolanthrone inhibits the reaction [[Diclofenac co-treated with IFNG protein] results in increased phosphorylation of STAT1 protein]
Diclofenac results in decreased expression of IFNG mRNA
CTD PMID:19393675 PMID:22285467 PMID:23395999 PMID:23939143 PMID:26609140 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 decreases expression EXP Diclofenac results in decreased expression of IFRD1 mRNA CTD PMID:35537566 NCBI chr12:40,253,128...40,273,184
Ensembl chr12:40,251,566...40,298,503
JBrowse link
G Igf1r insulin-like growth factor I receptor affects expression ISO Diclofenac affects the expression of IGF1R mRNA CTD PMID:24752500 NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416
JBrowse link
G Igf2r insulin-like growth factor 2 receptor multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in increased expression of IGF2R mRNA CTD PMID:37844793 NCBI chr17:12,901,293...12,988,593
Ensembl chr17:12,901,293...12,988,551
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 affects expression
increases expression
ISO
EXP
Diclofenac affects the expression of IGFBP1 mRNA
Diclofenac results in increased expression of IGFBP1 mRNA
CTD PMID:24752500 PMID:26934552 NCBI chr11:7,147,787...7,152,546
Ensembl chr11:7,147,782...7,152,546
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 decreases expression EXP Diclofenac results in decreased expression of IGFBP2 mRNA CTD PMID:26934552 NCBI chr 1:72,863,650...72,891,633
Ensembl chr 1:72,863,662...72,891,633
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 affects expression ISO Diclofenac affects the expression of IGFBP3 mRNA CTD PMID:24752500 NCBI chr11:7,156,086...7,165,498
Ensembl chr11:7,156,086...7,163,923
JBrowse link
G Igkv8-24 immunoglobulin kappa chain variable 8-24 increases expression ISO Diclofenac results in increased expression of IGKV8-24 mRNA CTD PMID:30723492 NCBI chr 6:70,193,842...70,194,405
Ensembl chr 6:70,193,842...70,194,405
JBrowse link
G Iigp1 interferon inducible GTPase 1 increases expression EXP Diclofenac results in increased expression of IIGP1 mRNA CTD PMID:26934552 NCBI chr18:60,506,688...60,525,706
Ensembl chr18:60,509,099...60,525,706
JBrowse link
G Ikbkb inhibitor of kappaB kinase beta multiple interactions ISO Diclofenac inhibits the reaction [Freund's Adjuvant results in increased phosphorylation of IKBKB protein] CTD PMID:25935278 NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605
JBrowse link
G Ikbke inhibitor of kappaB kinase epsilon increases expression EXP Diclofenac results in increased expression of IKBKE mRNA CTD PMID:26934552 NCBI chr 1:131,182,337...131,207,339
Ensembl chr 1:131,182,080...131,207,344
JBrowse link
G Ikbkg inhibitor of kappaB kinase gamma affects expression ISO Diclofenac affects the expression of IKBKG mRNA CTD PMID:24752500 NCBI chr  X:73,436,883...73,498,013
Ensembl chr  X:73,436,896...73,497,460
JBrowse link
G Il10 interleukin 10 increases response to substance
multiple interactions
ISO IL10 gene polymorphism results in increased susceptibility to Diclofenac
[Gum Arabic co-treated with Water deficiency co-treated with Diclofenac] results in increased expression of IL10 protein; Diclofenac promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL10 protein]
CTD PMID:15122773 PMID:23939143 PMID:31042592 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il12rb1 interleukin 12 receptor, beta 1 increases expression ISO Diclofenac results in increased expression of IL12RB1 mRNA CTD PMID:30723492 NCBI chr 8:71,261,005...71,276,186
Ensembl chr 8:71,261,093...71,274,068
JBrowse link
G Il13ra1 interleukin 13 receptor, alpha 1 increases expression EXP Diclofenac results in increased expression of IL13RA1 mRNA CTD PMID:26934552 NCBI chr  X:35,375,761...35,434,915
Ensembl chr  X:35,375,763...35,434,912
JBrowse link
G Il16 interleukin 16 decreases expression EXP Diclofenac results in decreased expression of IL16 mRNA CTD PMID:35537566 NCBI chr 7:83,292,027...83,395,479
Ensembl chr 7:83,292,033...83,394,934
JBrowse link
G Il17a interleukin 17A increases expression
multiple interactions
EXP
ISO
Diclofenac results in increased expression of IL17A protein
Diclofenac inhibits the reaction [Freund's Adjuvant results in increased expression of IL17A protein]
CTD PMID:22285467 PMID:25450234 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720
JBrowse link
G Il18 interleukin 18 multiple interactions
increases expression
ISO diacerein inhibits the reaction [Diclofenac results in increased expression of IL18 protein] CTD PMID:38582345 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il18bp interleukin 18 binding protein increases expression EXP Diclofenac results in increased expression of IL18BP mRNA CTD PMID:26934552 NCBI chr 7:101,664,281...101,669,699
Ensembl chr 7:101,664,092...101,667,897
JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression
ISO [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Diclofenac
Diclofenac results in increased expression of IL1A mRNA
CTD PMID:19362101 PMID:32816093 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
ISO
EXP
Diclofenac inhibits the reaction [IL1B protein results in increased activity of PTGS2 protein]
Diclofenac inhibits the reaction [Freund's Adjuvant results in increased expression of IL1B protein]
Diclofenac results in increased expression of IL1B mRNA
Diclofenac results in increased expression of IL1B mRNA; Diclofenac results in increased expression of IL1B protein
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; [Water deficiency co-treated with Diclofenac] results in increased expression of IL1B protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; diacerein inhibits the reaction [Diclofenac results in increased expression of IL1B protein]; Diclofenac inhibits the reaction [Freund's Adjuvant results in increased expression of IL1B protein]; Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in decreased expression of NFKBIA protein]; Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]; Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 protein]; Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein]; Diclofenac promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]; Diclofenac promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in increased expression of IL1B protein]; RELA mutant form inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; SN50 peptide inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]
CTD PMID:15135310 PMID:15705740 PMID:19393675 PMID:22285467 PMID:23395999 More... NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il1r1 interleukin 1 receptor, type I affects expression
increases expression
ISO
EXP
Diclofenac affects the expression of IL1R1 mRNA
Diclofenac results in increased expression of IL1R1 mRNA
CTD PMID:24752500 PMID:26934552 NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417
JBrowse link
G Il1r2 interleukin 1 receptor, type II increases expression EXP
ISO
Diclofenac results in increased expression of IL1R2 mRNA CTD PMID:26934552 PMID:30723492 NCBI chr 1:40,123,872...40,164,390
Ensembl chr 1:40,113,239...40,164,391
JBrowse link
G Il1rn interleukin 1 receptor antagonist increases expression
decreases expression
increases secretion
multiple interactions
ISO
EXP
Diclofenac results in increased expression of IL1RN mRNA
Diclofenac results in decreased expression of IL1RN mRNA
Diclofenac results in increased secretion of IL1RN protein
Lipopolysaccharides inhibits the reaction [Diclofenac results in increased secretion of IL1RN protein]
CTD PMID:9491209 PMID:26934552 PMID:35537566 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
JBrowse link
G Il2 interleukin 2 multiple interactions ISO Diclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein] CTD PMID:29777833 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il23a interleukin 23, alpha subunit p19 decreases expression ISO Diclofenac results in decreased expression of IL23A mRNA CTD PMID:19192274 NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621
JBrowse link
G Il24 interleukin 24 increases expression ISO Diclofenac results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr 1:130,809,801...130,815,153
Ensembl chr 1:130,809,811...130,815,191
JBrowse link
G Il2rg interleukin 2 receptor, gamma chain increases expression EXP Diclofenac results in increased expression of IL2RG mRNA CTD PMID:26934552 NCBI chr  X:100,307,991...100,311,861
Ensembl chr  X:100,307,984...100,311,861
JBrowse link
G Il33 interleukin 33 increases expression
decreases expression
EXP Diclofenac results in increased expression of IL33 mRNA
Diclofenac results in decreased expression of IL33 mRNA
CTD PMID:26934552 NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118
JBrowse link
G Il4 interleukin 4 increases response to substance ISO IL4 gene polymorphism results in increased susceptibility to Diclofenac CTD PMID:15122773 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il5 interleukin 5 multiple interactions ISO Diclofenac inhibits the reaction [nickel sulfate results in increased secretion of IL5 protein] CTD PMID:15663561 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
decreases expression
ISO
EXP
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Diclofenac; Diclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; Diclofenac inhibits the reaction [Mustard Gas results in increased secretion of IL6 protein]; lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Diclofenac results in increased expression of IL6 protein]
Diclofenac results in increased expression of IL6 mRNA
Diclofenac results in decreased expression of IL6 mRNA; Diclofenac results in decreased expression of IL6 protein
Diclofenac results in increased expression of IL6 mRNA; Diclofenac results in increased expression of IL6 protein
Diclofenac inhibits the reaction [Carrageenan results in increased expression of IL6 protein]; Diclofenac inhibits the reaction [Freund's Adjuvant results in increased expression of IL6 protein]; Diclofenac promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]; Diclofenac promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 protein]
CTD PMID:19192274 PMID:19362101 PMID:23506792 PMID:23939143 PMID:24412305 More... NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Immt inner membrane protein, mitochondrial affects expression EXP Diclofenac affects the expression of IMMT mRNA CTD PMID:26934552 NCBI chr 6:71,806,200...71,852,250
Ensembl chr 6:71,808,315...71,854,372
JBrowse link
G Inhbb inhibin beta-B increases expression EXP
ISO
Diclofenac results in increased expression of INHBB mRNA CTD PMID:26934552 PMID:30723492 NCBI chr 1:119,343,193...119,349,978
Ensembl chr 1:119,343,195...119,349,978
JBrowse link
G Inka2 inka box actin regulator 2 increases expression EXP Diclofenac results in increased expression of INKA2 mRNA CTD PMID:35537566 NCBI chr 3:105,611,915...105,628,158
Ensembl chr 3:105,611,915...105,628,158
JBrowse link
G Inmt indolethylamine N-methyltransferase decreases expression EXP Diclofenac results in decreased expression of INMT mRNA CTD PMID:26934552 NCBI chr 6:55,147,612...55,151,975
Ensembl chr 6:55,147,611...55,152,028
JBrowse link
G Insl3 insulin-like 3 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of INSL3 mRNA CTD PMID:37844793 NCBI chr 8:72,141,896...72,143,221
Ensembl chr 8:72,141,858...72,143,219
JBrowse link
G Insl6 insulin-like 6 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of INSL6 mRNA CTD PMID:37844793 NCBI chr19:29,298,754...29,302,718
Ensembl chr19:29,298,744...29,302,756
JBrowse link
G Insr insulin receptor affects expression ISO Diclofenac affects the expression of INSR mRNA CTD PMID:24752500 NCBI chr 8:3,200,922...3,329,649
Ensembl chr 8:3,172,061...3,329,617
JBrowse link
G Iqcf1 IQ motif containing F1 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of IQCF1 mRNA CTD PMID:37844793 NCBI chr 9:106,377,166...106,379,449
Ensembl chr 9:106,377,166...106,379,453
JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 increases expression EXP Diclofenac results in increased expression of IRAK4 mRNA CTD PMID:26934552 NCBI chr15:94,441,495...94,466,198
Ensembl chr15:94,441,524...94,479,696
JBrowse link
G Irf7 interferon regulatory factor 7 decreases expression ISO Diclofenac results in decreased expression of IRF7 mRNA CTD PMID:19192274 NCBI chr 7:140,843,096...140,846,412
Ensembl chr 7:140,842,619...140,846,394
JBrowse link
G Irgm1 immunity-related GTPase family M member 1 increases expression EXP Diclofenac results in increased expression of IRGM1 mRNA CTD PMID:26934552 NCBI chr11:48,756,072...48,762,247
Ensembl chr11:48,752,795...48,762,510
JBrowse link
G Irgm2 immunity-related GTPase family M member 2 increases expression EXP Diclofenac results in increased expression of IRGM2 mRNA CTD PMID:26934552 NCBI chr11:58,105,803...58,113,609
Ensembl chr11:58,090,444...58,113,608
JBrowse link
G Irs1 insulin receptor substrate 1 affects expression ISO
EXP
Diclofenac affects the expression of IRS1 mRNA CTD PMID:24752500 PMID:26934552 NCBI chr 1:82,210,826...82,269,160
Ensembl chr 1:82,210,822...82,269,137
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier decreases expression ISO Diclofenac results in decreased expression of ISG15 mRNA CTD PMID:19192274 NCBI chr 4:156,283,881...156,285,275
Ensembl chr 4:156,283,912...156,285,253
JBrowse link
G Isg20 interferon-stimulated protein decreases expression ISO Diclofenac results in decreased expression of ISG20 mRNA CTD PMID:19192274 NCBI chr 7:78,561,136...78,570,144
Ensembl chr 7:78,563,172...78,570,144
JBrowse link
G Isyna1 myo-inositol 1-phosphate synthase A1 increases expression EXP Diclofenac results in increased expression of ISYNA1 mRNA CTD PMID:26934552 NCBI chr 8:71,047,131...71,049,940
Ensembl chr 8:71,047,023...71,049,940
JBrowse link
G Itga2 integrin alpha 2 affects expression ISO Diclofenac affects the expression of ITGA2 mRNA CTD PMID:24752500 NCBI chr13:114,969,617...115,068,588
Ensembl chr13:114,969,617...115,068,636
JBrowse link
G Itgal integrin alpha L increases expression EXP Diclofenac results in increased expression of ITGAL mRNA CTD PMID:26934552 NCBI chr 7:126,895,404...126,934,309
Ensembl chr 7:126,895,432...126,934,310
JBrowse link
G Itgam integrin alpha M increases expression EXP Diclofenac results in increased expression of ITGAM mRNA CTD PMID:27671914 NCBI chr 7:127,661,812...127,717,663
Ensembl chr 7:127,661,812...127,717,663
JBrowse link
G Itgax integrin alpha X decreases expression EXP Diclofenac results in decreased expression of ITGAX mRNA CTD PMID:35537566 NCBI chr 7:127,728,697...127,749,829
Ensembl chr 7:127,728,719...127,749,829
JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) affects expression ISO Diclofenac affects the expression of ITGB1 mRNA CTD PMID:24752500 NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681
JBrowse link
G Itgb2 integrin beta 2 increases expression EXP Diclofenac results in increased expression of ITGB2 mRNA CTD PMID:26934552 NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542
JBrowse link
G Itgb3 integrin beta 3 multiple interactions ISO Diclofenac inhibits the reaction [TNF protein results in increased expression of ITGB3 protein] CTD PMID:19691487 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302
JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 increases expression EXP Diclofenac results in increased expression of ITIH3 mRNA CTD PMID:26934552 NCBI chr14:30,630,529...30,645,748
Ensembl chr14:30,630,529...30,645,717
JBrowse link
G Itih4 inter alpha-trypsin inhibitor, heavy chain 4 increases expression EXP Diclofenac results in increased expression of ITIH4 mRNA CTD PMID:26934552 NCBI chr14:30,608,433...30,623,943
Ensembl chr14:30,608,433...30,624,310
JBrowse link
G Itm2a integral membrane protein 2A increases expression ISO Diclofenac results in increased expression of ITM2A mRNA CTD PMID:17379860 NCBI chr  X:106,440,801...106,446,966
Ensembl chr  X:106,440,705...106,446,982
JBrowse link
G Jade2 jade family PHD finger 2 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in increased expression of JADE2 mRNA CTD PMID:37844793 NCBI chr11:51,704,278...51,749,835
Ensembl chr11:51,704,282...51,748,480
JBrowse link
G Jade3 jade family PHD finger 3 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in increased expression of JADE3 mRNA CTD PMID:37844793 NCBI chr  X:20,291,611...20,386,178
Ensembl chr  X:20,291,927...20,386,178
JBrowse link
G Jdp2 Jun dimerization protein 2 decreases expression EXP Diclofenac results in decreased expression of JDP2 mRNA CTD PMID:35537566 NCBI chr12:85,645,190...85,686,652
Ensembl chr12:85,645,801...85,686,652
JBrowse link
G Jun jun proto-oncogene affects expression
increases expression
ISO
EXP
Diclofenac affects the expression of JUN mRNA
Diclofenac results in increased expression of JUN mRNA
CTD PMID:24752500 PMID:26934552 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Junb jun B proto-oncogene multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of JUNB mRNA CTD PMID:37844793 NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347
JBrowse link
G Jund jun D proto-oncogene increases expression ISO Diclofenac results in increased expression of JUND mRNA CTD PMID:19022234 NCBI chr 8:71,150,389...71,153,265
Ensembl chr 8:71,151,599...71,153,265
JBrowse link
G Kat6b K(lysine) acetyltransferase 6B affects expression ISO Diclofenac affects the expression of KAT6B mRNA CTD PMID:24752500 NCBI chr14:21,549,284...21,722,546
Ensembl chr14:21,531,502...21,722,546
JBrowse link
G Kbtbd11 kelch repeat and BTB (POZ) domain containing 11 increases expression ISO Diclofenac results in increased expression of KBTBD11 mRNA CTD PMID:30723492 NCBI chr 8:15,059,408...15,083,333
Ensembl chr 8:15,061,025...15,083,333
JBrowse link
G Khdc3 KH domain containing 3, subcortical maternal complex member increases expression ISO Diclofenac results in increased expression of KHDC3 mRNA CTD PMID:30723492 NCBI chr 9:73,008,660...73,013,915
Ensembl chr 9:73,009,118...73,011,720
JBrowse link
G Kif5c kinesin family member 5C increases expression ISO Diclofenac results in increased expression of KIF5C mRNA CTD PMID:30723492 NCBI chr 2:49,509,298...49,664,790
Ensembl chr 2:49,509,310...49,664,790
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in increased expression of KIT mRNA CTD PMID:37844793 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382
JBrowse link
G Klf4 Kruppel-like transcription factor 4 (gut) decreases expression EXP Diclofenac results in decreased expression of KLF4 mRNA CTD PMID:35537566 NCBI chr 4:55,527,137...55,536,984
Ensembl chr 4:55,527,143...55,532,466
JBrowse link
G Klhl33 kelch-like 33 decreases expression EXP Diclofenac results in decreased expression of KLHL33 mRNA CTD PMID:35537566 NCBI chr14:51,126,038...51,134,940
Ensembl chr14:51,126,039...51,134,964
JBrowse link
G Klk1 kallikrein 1 increases expression EXP Diclofenac results in increased expression of KLK1 protein CTD PMID:23506792 NCBI chr 7:43,874,784...43,879,046
Ensembl chr 7:43,874,784...43,879,042
JBrowse link
G Klrb1b killer cell lectin-like receptor subfamily B member 1B increases expression EXP Diclofenac results in increased expression of KLRB1B mRNA CTD PMID:26934552 NCBI chr 6:128,790,669...128,803,278
Ensembl chr 6:128,790,669...128,803,294
JBrowse link
G Kndc1 kinase non-catalytic C-lobe domain (KIND) containing 1 increases expression ISO Diclofenac results in increased expression of KNDC1 mRNA CTD PMID:30723492 NCBI chr 7:139,474,612...139,521,453
Ensembl chr 7:139,474,612...139,521,450
JBrowse link
G Kng1 kininogen 1 multiple interactions
increases expression
ISO [Diclofenac co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of KNG1 protein; lipopolysaccharide, E coli O55-B5 promotes the reaction [Diclofenac results in increased expression of KNG1 protein] CTD PMID:25772430 NCBI chr16:22,876,970...22,900,828
Ensembl chr16:22,876,615...22,900,828
JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog affects expression ISO Diclofenac affects the expression of KRAS mRNA CTD PMID:24752500 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965
JBrowse link
G Lax1 lymphocyte transmembrane adaptor 1 decreases expression EXP Diclofenac results in decreased expression of LAX1 mRNA CTD PMID:26934552 NCBI chr 1:133,606,767...133,620,760
Ensembl chr 1:133,606,829...133,617,846
JBrowse link
G Lbp lipopolysaccharide binding protein decreases expression
affects expression
increases expression
EXP Diclofenac results in decreased expression of LBP mRNA
Diclofenac affects the expression of LBP mRNA
Diclofenac results in increased expression of LBP protein
CTD PMID:26934552 NCBI chr 2:158,148,413...158,174,772
Ensembl chr 2:158,148,413...158,174,772
JBrowse link
G Lce1d late cornified envelope 1D decreases expression EXP Diclofenac results in decreased expression of LCE1D mRNA CTD PMID:26934552 NCBI chr 3:92,592,806...92,594,517
Ensembl chr 3:92,592,806...92,594,517
JBrowse link
G Lcn2 lipocalin 2 increases expression
increases secretion
multiple interactions
ISO
EXP
Diclofenac results in increased expression of LCN2 mRNA
Diclofenac results in increased secretion of LCN2 protein
diacerein inhibits the reaction [Diclofenac results in increased secretion of LCN2 protein]; Diclofenac inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of LCN2 protein]; Diclofenac promotes the reaction [Buthionine Sulfoximine results in increased expression of LCN2 mRNA]
CTD PMID:23939143 PMID:26934552 PMID:38582345 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264
JBrowse link
G Lcp2 lymphocyte cytosolic protein 2 increases expression EXP Diclofenac results in increased expression of LCP2 mRNA CTD PMID:26934552 NCBI chr11:33,996,928...34,042,281
Ensembl chr11:33,996,920...34,042,295
JBrowse link
G Ldha lactate dehydrogenase A increases expression ISO Diclofenac results in increased expression of LDHA protein CTD PMID:25772430 NCBI chr 7:46,491,698...46,505,051
Ensembl chr 7:46,490,899...46,505,051
JBrowse link
G Leap2 liver-expressed antimicrobial peptide 2 increases expression EXP Diclofenac results in increased expression of LEAP2 mRNA CTD PMID:26934552 NCBI chr11:53,313,008...53,313,963
Ensembl chr11:53,313,008...53,313,997
JBrowse link
G Lepr leptin receptor affects expression
increases expression
EXP Diclofenac affects the expression of LEPR mRNA
Diclofenac results in increased expression of LEPR protein
CTD PMID:26934552 NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549
JBrowse link
G Lgals3 lectin, galactose binding, soluble 3 increases expression EXP Diclofenac results in increased expression of LGALS3 mRNA CTD PMID:26934552 NCBI chr14:47,611,317...47,623,624
Ensembl chr14:47,605,208...47,623,617
JBrowse link
G Lgmn legumain increases expression EXP Diclofenac results in increased expression of LGMN mRNA CTD PMID:26934552 NCBI chr12:102,360,341...102,405,987
Ensembl chr12:102,360,343...102,406,072
JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 increases expression EXP Diclofenac results in increased expression of LGR4 mRNA CTD PMID:35537566 NCBI chr 2:109,747,919...109,844,602
Ensembl chr 2:109,747,992...109,844,602
JBrowse link
G Lhx2 LIM homeobox protein 2 decreases expression EXP Diclofenac results in decreased expression of LHX2 mRNA CTD PMID:35537566 NCBI chr 2:38,229,282...38,259,747
Ensembl chr 2:38,229,293...38,259,745
JBrowse link
G Lifr LIF receptor alpha decreases expression EXP Diclofenac results in decreased expression of LIFR mRNA CTD PMID:26934552 NCBI chr15:7,120,091...7,226,970
Ensembl chr15:7,120,095...7,226,970
JBrowse link
G Lipc lipase, hepatic decreases expression EXP Diclofenac results in decreased expression of LIPC mRNA CTD PMID:26934552 NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508
JBrowse link
G Litaf LPS-induced TN factor increases expression EXP Diclofenac results in increased expression of LITAF mRNA CTD PMID:26934552 NCBI chr16:10,777,137...10,810,985
Ensembl chr16:10,777,139...10,884,021
JBrowse link
G Lmnb1 lamin B1 increases expression EXP Diclofenac results in increased expression of LMNB1 mRNA CTD PMID:35537566 NCBI chr18:56,840,885...56,886,496
Ensembl chr18:56,840,885...56,886,496
JBrowse link
G Lmo4 LIM domain only 4 decreases expression EXP Diclofenac results in decreased expression of LMO4 mRNA CTD PMID:35537566 NCBI chr 3:143,894,291...143,911,016
Ensembl chr 3:143,894,291...143,910,981
JBrowse link
G Lpar4 lysophosphatidic acid receptor 4 decreases expression EXP Diclofenac results in decreased expression of LPAR4 mRNA CTD PMID:26934552 NCBI chr  X:105,964,231...105,977,505
Ensembl chr  X:105,964,231...105,977,506
JBrowse link
G Lpl lipoprotein lipase increases expression EXP Diclofenac results in increased expression of LPL mRNA CTD PMID:26934552 NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100
JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 increases expression EXP Diclofenac results in increased expression of LRG1 mRNA CTD PMID:26934552 NCBI chr17:56,426,678...56,428,946
Ensembl chr17:56,426,678...56,429,001
JBrowse link
G Lrp8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor increases expression EXP Diclofenac results in increased expression of LRP8 mRNA CTD PMID:35537566 NCBI chr 4:107,659,337...107,734,037
Ensembl chr 4:107,659,066...107,734,037
JBrowse link
G Ltc4s leukotriene C4 synthase increases expression ISO Diclofenac results in increased expression of LTC4S mRNA CTD PMID:30723492 NCBI chr11:50,127,288...50,129,378
Ensembl chr11:50,127,288...50,129,443
JBrowse link
G Lxn latexin increases expression ISO Diclofenac results in increased expression of LXN mRNA CTD PMID:19192274 NCBI chr 3:67,365,332...67,371,240
Ensembl chr 3:67,365,331...67,371,259
JBrowse link
G Ly6e lymphocyte antigen 6 family member E decreases expression
increases expression
ISO
EXP
Diclofenac results in decreased expression of LY6E mRNA
Diclofenac results in increased expression of LY6E mRNA
CTD PMID:19192274 PMID:26934552 NCBI chr15:74,826,874...74,831,753
Ensembl chr15:74,826,900...74,831,752
JBrowse link
G Ly6g lymphocyte antigen 6 family member G increases expression EXP Diclofenac results in increased expression of LY6G mRNA CTD PMID:27671914 NCBI chr15:75,027,110...75,030,977
Ensembl chr15:75,027,089...75,030,975
JBrowse link
G Ly75 lymphocyte antigen 75 increases expression EXP Diclofenac results in increased expression of LY75 mRNA CTD PMID:26934552 NCBI chr 2:60,122,447...60,213,617
Ensembl chr 2:60,122,447...60,213,647
JBrowse link
G Lyz2 lysozyme 2 increases expression EXP Diclofenac results in increased expression of LYZ2 mRNA CTD PMID:26934552 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
JBrowse link
G Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 affects expression ISO Diclofenac affects the expression of MAGI1 mRNA CTD PMID:24752500 NCBI chr 6:93,652,434...94,260,906
Ensembl chr 6:93,652,436...94,260,898
JBrowse link
G Malsu1 mitochondrial assembly of ribosomal large subunit 1 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of MALSU1 mRNA CTD PMID:37844793 NCBI chr 6:49,050,729...49,116,078
Ensembl chr 6:49,050,729...49,063,685
JBrowse link
G Maoa monoamine oxidase A affects expression ISO Diclofenac affects the expression of MAOA mRNA CTD PMID:24752500 NCBI chr  X:16,485,937...16,554,051
Ensembl chr  X:16,485,937...16,554,057
JBrowse link
G Maob monoamine oxidase B affects expression ISO Diclofenac affects the expression of MAOB mRNA CTD PMID:24752500 NCBI chr  X:16,575,520...16,683,605
Ensembl chr  X:16,575,521...16,683,605
JBrowse link
G Map2k3 mitogen-activated protein kinase kinase 3 affects expression ISO Diclofenac affects the expression of MAP2K3 mRNA CTD PMID:24752500 NCBI chr11:60,822,880...60,843,637
Ensembl chr11:60,822,859...60,843,637
JBrowse link
G Map2k5 mitogen-activated protein kinase kinase 5 affects expression ISO Diclofenac affects the expression of MAP2K5 mRNA CTD PMID:24752500 NCBI chr 9:63,071,050...63,288,964
Ensembl chr 9:63,071,050...63,285,184
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 affects expression ISO Diclofenac affects the expression of MAP2K6 mRNA CTD PMID:24752500 NCBI chr11:110,289,928...110,416,348
Ensembl chr11:110,289,948...110,416,348
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression EXP Diclofenac results in increased expression of MAP3K1 mRNA CTD PMID:26934552 NCBI chr13:111,882,962...111,954,803
Ensembl chr13:111,882,962...111,945,527
JBrowse link
G Map3k12 mitogen-activated protein kinase kinase kinase 12 decreases expression ISO Diclofenac results in decreased expression of MAP3K12 mRNA CTD PMID:18172885 NCBI chr15:102,406,079...102,425,311
Ensembl chr15:102,406,081...102,425,499
JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 affects expression ISO Diclofenac affects the expression of MAP3K7 mRNA CTD PMID:24752500 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467
JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 affects expression ISO Diclofenac affects the expression of MAP4K4 mRNA CTD PMID:24752500 NCBI chr 1:39,939,806...40,065,470
Ensembl chr 1:39,940,073...40,065,470
JBrowse link
G Map7d1 MAP7 domain containing 1 increases expression EXP Diclofenac results in increased expression of MAP7D1 mRNA CTD PMID:26934552 NCBI chr 4:126,125,960...126,150,112
Ensembl chr 4:126,125,960...126,150,136
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation
ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Diclofenac results in increased phosphorylation of MAPK1 protein]; 2-aminoethoxydiphenyl borate inhibits the reaction [Diclofenac results in increased phosphorylation of MAPK1 protein]; Calcium promotes the reaction [Diclofenac results in increased phosphorylation of MAPK1 protein]; pyrazolanthrone inhibits the reaction [Diclofenac results in increased phosphorylation of MAPK1 protein]
Diclofenac analog results in increased phosphorylation of MAPK1 protein; Diclofenac results in increased phosphorylation of MAPK1 protein
CTD PMID:24104198 PMID:26609140 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk13 mitogen-activated protein kinase 13 affects expression ISO Diclofenac affects the expression of MAPK13 mRNA CTD PMID:24752500 NCBI chr17:28,988,260...28,997,678
Ensembl chr17:28,988,271...28,999,207
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 affects expression ISO Diclofenac affects the expression of MAPK14 mRNA CTD PMID:24752500 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Diclofenac results in increased phosphorylation of MAPK3 protein]; 2-aminoethoxydiphenyl borate inhibits the reaction [Diclofenac results in increased phosphorylation of MAPK3 protein]; Calcium promotes the reaction [Diclofenac results in increased phosphorylation of MAPK3 protein]; pyrazolanthrone inhibits the reaction [Diclofenac results in increased phosphorylation of MAPK3 protein]
Diclofenac analog results in increased phosphorylation of MAPK3 protein; Diclofenac results in increased phosphorylation of MAPK3 protein
CTD PMID:24104198 PMID:26609140 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 affects expression ISO Diclofenac affects the expression of MAPK8 mRNA CTD PMID:24752500 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 increases expression EXP Diclofenac results in increased expression of MAPK8IP3 mRNA CTD PMID:26934552 NCBI chr17:25,116,480...25,155,951
Ensembl chr17:25,111,127...25,155,942
JBrowse link
G Mapkapk3 mitogen-activated protein kinase-activated protein kinase 3 increases expression EXP Diclofenac results in increased expression of MAPKAPK3 mRNA CTD PMID:26934552 NCBI chr 9:107,132,125...107,167,082
Ensembl chr 9:107,132,126...107,167,076
JBrowse link
G Marchf1 membrane associated ring-CH-type finger 1 increases expression EXP Diclofenac results in increased expression of MARCHF1 mRNA CTD PMID:26934552 PMID:35537566 NCBI chr 8:66,070,558...66,925,761
Ensembl chr 8:66,070,552...66,924,289
JBrowse link
G Marco macrophage receptor with collagenous structure increases expression
decreases expression
EXP Diclofenac results in increased expression of MARCO mRNA
Diclofenac results in decreased expression of MARCO mRNA
CTD PMID:26934552 NCBI chr 1:120,402,267...120,432,753
Ensembl chr 1:120,402,267...120,432,753
JBrowse link
G Mastl microtubule associated serine/threonine kinase-like decreases expression EXP Diclofenac results in decreased expression of MASTL mRNA CTD PMID:26934552 PMID:35537566 NCBI chr 2:23,006,549...23,046,036
Ensembl chr 2:23,005,618...23,046,036
JBrowse link
G Mbl1 mannose-binding lectin (protein A) 1 increases expression EXP Diclofenac results in increased expression of MBL1 mRNA CTD PMID:26934552 NCBI chr14:40,873,413...40,885,861
Ensembl chr14:40,873,415...40,881,558
JBrowse link
G Mcam melanoma cell adhesion molecule decreases expression EXP Diclofenac results in decreased expression of MCAM mRNA CTD PMID:35537566 NCBI chr 9:44,045,958...44,054,024
Ensembl chr 9:44,045,766...44,054,024
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 affects expression ISO Diclofenac affects the expression of MCM7 mRNA CTD PMID:24752500 NCBI chr 5:138,162,845...138,170,675
Ensembl chr 5:138,162,845...138,170,684
JBrowse link
G Mctp1 multiple C2 domains, transmembrane 1 increases expression ISO Diclofenac results in increased expression of MCTP1 mRNA CTD PMID:30723492 NCBI chr13:76,530,481...77,181,403
Ensembl chr13:76,532,259...77,179,929
JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 decreases expression ISO Diclofenac results in decreased expression of MDM2 mRNA CTD PMID:17202759 NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663
JBrowse link
G Mecom MDS1 and EVI1 complex locus decreases expression EXP Diclofenac results in decreased expression of MECOM mRNA CTD PMID:26934552 NCBI chr 3:30,005,445...30,563,937
Ensembl chr 3:30,005,445...30,602,157
JBrowse link
G Med10 mediator complex subunit 10 affects expression ISO Diclofenac affects the expression of MED10 mRNA CTD PMID:24752500 NCBI chr13:69,950,467...69,964,221
Ensembl chr13:69,950,514...69,964,223
JBrowse link
G Med13 mediator complex subunit 13 affects expression ISO Diclofenac affects the expression of MED13 mRNA CTD PMID:24752500 NCBI chr11:86,157,859...86,248,422
Ensembl chr11:86,157,859...86,248,428
JBrowse link
G Med13l mediator complex subunit 13-like affects expression ISO Diclofenac affects the expression of MED13L mRNA CTD PMID:24752500 NCBI chr 5:118,698,363...118,903,503
Ensembl chr 5:118,698,744...118,903,503
JBrowse link
G Med14 mediator complex subunit 14 affects expression ISO Diclofenac affects the expression of MED14 mRNA CTD PMID:24752500 NCBI chr  X:12,541,607...12,628,813
Ensembl chr  X:12,541,608...12,628,312
JBrowse link
G Med17 mediator complex subunit 17 affects expression ISO Diclofenac affects the expression of MED17 mRNA CTD PMID:24752500 NCBI chr 9:15,171,647...15,194,576
Ensembl chr 9:15,171,647...15,191,227
JBrowse link
G Med30 mediator complex subunit 30 affects expression ISO Diclofenac affects the expression of MED30 mRNA CTD PMID:24752500 NCBI chr15:52,575,841...52,593,827
Ensembl chr15:52,575,804...52,593,960
JBrowse link
G Med31 mediator complex subunit 31 affects expression ISO Diclofenac affects the expression of MED31 mRNA CTD PMID:24752500 NCBI chr11:72,102,550...72,106,418
Ensembl chr11:72,102,550...72,106,418
JBrowse link
G Med6 mediator complex subunit 6 affects expression ISO Diclofenac affects the expression of MED6 mRNA CTD PMID:24752500 NCBI chr12:81,620,331...81,641,782
Ensembl chr12:81,620,331...81,641,782
JBrowse link
G Mef2a myocyte enhancer factor 2A affects expression ISO Diclofenac affects the expression of MEF2A mRNA CTD PMID:24752500 NCBI chr 7:66,880,911...67,026,435
Ensembl chr 7:66,880,911...67,022,606
JBrowse link
G Meig1 meiosis expressed gene 1 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of MEIG1 mRNA CTD PMID:37844793 NCBI chr 2:3,410,080...3,423,685
Ensembl chr 2:3,410,080...3,423,685
JBrowse link
G Met met proto-oncogene decreases expression
increases expression
ISO Diclofenac results in decreased expression of MET mRNA
Diclofenac results in increased expression of MET mRNA
CTD PMID:19192274 PMID:32816093 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979
JBrowse link
G Mfn1 mitofusin 1 decreases expression
multiple interactions
ISO Diclofenac results in decreased expression of MFN1 protein
AICA ribonucleotide inhibits the reaction [Diclofenac results in decreased expression of MFN1 protein]
CTD PMID:27792760 NCBI chr 3:32,583,594...32,633,384
Ensembl chr 3:32,583,614...32,633,388
JBrowse link
G Mfn2 mitofusin 2 multiple interactions
decreases expression
ISO AICA ribonucleotide inhibits the reaction [Diclofenac results in decreased expression of MFN2 protein] CTD PMID:27792760 NCBI chr 4:147,958,043...147,989,527
Ensembl chr 4:147,958,056...147,989,161
JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid increases expression EXP Diclofenac results in increased expression of MFSD2A mRNA CTD PMID:35537566 NCBI chr 4:122,840,643...122,855,844
Ensembl chr 4:122,840,643...122,854,981
JBrowse link
G Mgll monoglyceride lipase decreases expression EXP Diclofenac results in decreased expression of MGLL mRNA CTD PMID:26934552 NCBI chr 6:88,701,397...88,805,342
Ensembl chr 6:88,701,394...88,805,342
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP Diclofenac results in increased expression of MGMT mRNA CTD PMID:35537566 NCBI chr 7:136,496,315...136,732,001
Ensembl chr 7:136,496,343...136,731,995
JBrowse link
G Mir122 microRNA 122 increases expression ISO Diclofenac results in increased expression of MIR122
Diclofenac results in increased expression of MIR122 mRNA
CTD PMID:25527335 PMID:30925002 NCBI chr18:65,381,932...65,381,997
Ensembl chr18:65,381,932...65,381,997
JBrowse link
G Mir192 microRNA 192 increases expression ISO Diclofenac results in increased expression of MIR192 mRNA CTD PMID:30925002 NCBI chr19:6,314,874...6,314,962
Ensembl chr19:6,314,874...6,314,962
JBrowse link
G Mir1a-1hg Mir1a-1 and Mir133a-2 host gene decreases expression EXP Diclofenac results in decreased expression of MIR1A-1HG mRNA CTD PMID:35537566 NCBI chr 2:180,027,397...180,043,595 JBrowse link
G Mirlet7d microRNA let7d decreases expression ISO Diclofenac results in decreased expression of MIRLET7D mRNA CTD PMID:30723492 NCBI chr13:48,689,488...48,689,590
Ensembl chr13:48,689,488...48,689,590
JBrowse link
G Mknk2 MAP kinase-interacting serine/threonine kinase 2 affects expression ISO Diclofenac affects the expression of MKNK2 mRNA CTD PMID:24752500 NCBI chr10:80,501,152...80,512,264
Ensembl chr10:80,501,161...80,513,946
JBrowse link
G Mkrn2 makorin, ring finger protein, 2 decreases expression EXP Diclofenac results in decreased expression of MKRN2 mRNA CTD PMID:35537566 NCBI chr 6:115,578,844...115,598,647
Ensembl chr 6:115,578,863...115,599,585
JBrowse link
G Mme membrane metallo endopeptidase decreases expression EXP Diclofenac results in decreased expression of MME mRNA CTD PMID:26934552 NCBI chr 3:63,202,632...63,291,134
Ensembl chr 3:63,148,958...63,293,451
JBrowse link
G Mmp12 matrix metallopeptidase 12 decreases expression ISO Diclofenac results in decreased expression of MMP12 mRNA CTD PMID:19192274 NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499
JBrowse link
G Mmp16 matrix metallopeptidase 16 increases expression EXP Diclofenac results in increased expression of MMP16 mRNA CTD PMID:26934552 NCBI chr 4:17,853,072...18,117,479
Ensembl chr 4:17,852,893...18,119,145
JBrowse link
G Mmp8 matrix metallopeptidase 8 increases expression ISO Diclofenac results in increased expression of MMP8 mRNA CTD PMID:30723492 NCBI chr 9:7,558,430...7,568,487
Ensembl chr 9:7,558,457...7,568,486
JBrowse link
G Mpeg1 macrophage expressed gene 1 increases expression EXP Diclofenac results in increased expression of MPEG1 mRNA CTD PMID:26934552 NCBI chr19:12,438,134...12,442,649
Ensembl chr19:12,438,143...12,442,649
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases expression
increases activity
ISO
EXP
Diclofenac inhibits the reaction [Carrageenan results in increased activity of MPO protein]; sodium nitrate inhibits the reaction [Diclofenac results in increased activity of MPO protein]
Diclofenac inhibits the reaction [Freund's Adjuvant results in increased expression of MPO protein]
Diclofenac results in increased expression of MPO mRNA
[Hydrogen Peroxide results in increased activity of MPO protein] which results in increased oxidation of and results in increased susceptibility to Diclofenac
CTD PMID:17275683 PMID:24412305 PMID:27671914 PMID:28754375 PMID:31926916 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Mr1 major histocompatibility complex, class I-related affects expression ISO Diclofenac affects the expression of MR1 mRNA CTD PMID:25811541 NCBI chr 1:155,003,620...155,022,560
Ensembl chr 1:155,003,023...155,022,560
JBrowse link
G Mras muscle and microspikes RAS affects expression ISO Diclofenac affects the expression of MRAS mRNA CTD PMID:24752500 NCBI chr 9:99,267,473...99,319,505
Ensembl chr 9:99,267,473...99,319,434
JBrowse link
G Mrpl15 mitochondrial ribosomal protein L15 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of MRPL15 mRNA CTD PMID:37844793 NCBI chr 1:4,843,432...4,855,949
Ensembl chr 1:4,843,429...4,855,962
JBrowse link
G Mrpl20 mitochondrial ribosomal protein L20 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of MRPL20 mRNA CTD PMID:37844793 NCBI chr 4:155,887,335...155,893,288
Ensembl chr 4:155,887,335...155,894,432
JBrowse link
G Mrpl32 mitochondrial ribosomal protein L32 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of MRPL32 mRNA CTD PMID:37844793 NCBI chr13:14,784,886...14,787,622
Ensembl chr13:14,782,769...14,787,750
JBrowse link
G Mrpl36 mitochondrial ribosomal protein L36 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of MRPL36 mRNA CTD PMID:37844793 NCBI chr13:73,479,128...73,480,297
Ensembl chr13:73,476,632...73,480,297
JBrowse link
G Mrpl52 mitochondrial ribosomal protein L52 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of MRPL52 mRNA CTD PMID:37844793 NCBI chr14:54,664,366...54,667,207
Ensembl chr14:54,664,366...54,667,213
JBrowse link
G Mrpl54 mitochondrial ribosomal protein L54 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of MRPL54 mRNA CTD PMID:37844793 NCBI chr10:81,100,556...81,102,760
Ensembl chr10:81,100,547...81,102,768
JBrowse link
G Mrpl57 mitochondrial ribosomal protein L57 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of MRPL57 mRNA CTD PMID:37844793 NCBI chr14:58,063,662...58,066,544
Ensembl chr14:58,063,691...58,066,753
JBrowse link
G Mrps11 mitochondrial ribosomal protein S11 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of MRPS11 mRNA CTD PMID:37844793 NCBI chr 7:78,432,879...78,442,736
Ensembl chr 7:78,432,867...78,442,737
JBrowse link
G Mrps14 mitochondrial ribosomal protein S14 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of MRPS14 mRNA CTD PMID:37844793 NCBI chr 1:160,022,785...160,028,756
Ensembl chr 1:160,022,785...160,029,740
JBrowse link
G Mrps16 mitochondrial ribosomal protein S16 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of MRPS16 mRNA CTD PMID:37844793 NCBI chr14:20,441,290...20,443,702
Ensembl chr14:20,439,372...20,443,702
JBrowse link
G Mrps18c mitochondrial ribosomal protein S18C multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of MRPS18C mRNA CTD PMID:37844793 NCBI chr 5:100,946,625...100,952,333
Ensembl chr 5:100,946,493...100,952,337
JBrowse link
G Mrps22 mitochondrial ribosomal protein S22 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of MRPS22 mRNA CTD PMID:37844793 NCBI chr 9:98,470,783...98,483,732
Ensembl chr 9:98,470,783...98,483,713
JBrowse link
G Mrps33 mitochondrial ribosomal protein S33 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of MRPS33 mRNA CTD PMID:37844793 NCBI chr 6:39,778,738...39,787,870
Ensembl chr 6:39,778,738...39,787,922
JBrowse link
G Ms4a14 membrane-spanning 4-domains, subfamily A, member 14 increases expression ISO Diclofenac results in increased expression of MS4A14 mRNA CTD PMID:30723492 NCBI chr19:11,278,613...11,293,239
Ensembl chr19:11,278,613...11,291,818
JBrowse link
G Mt1 metallothionein 1 increases expression
multiple interactions
EXP Diclofenac results in increased expression of MT1 mRNA
[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in increased expression of MT1 mRNA; [Sodium Selenite co-treated with Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in increased expression of MT1 mRNA
CTD PMID:26934552 PMID:38945390 NCBI chr 8:94,905,214...94,906,955
Ensembl chr 8:94,905,710...94,906,955
JBrowse link
G Mt2 metallothionein 2 increases expression
multiple interactions
EXP Diclofenac results in increased expression of MT2 mRNA
[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in increased expression of MT2 mRNA; [Sodium Selenite co-treated with Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in increased expression of MT2 mRNA
CTD PMID:26934552 PMID:38945390 NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196
JBrowse link
G Mtbp Mdm2, transformed 3T3 cell double minute p53 binding protein decreases expression EXP Diclofenac results in decreased expression of MTBP mRNA CTD PMID:35537566 NCBI chr15:55,420,800...55,489,819
Ensembl chr15:55,420,804...55,489,819
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase affects expression
decreases expression
ISO
EXP
Diclofenac affects the expression of MTHFD2 mRNA
Diclofenac results in decreased expression of MTHFD2 mRNA
CTD PMID:24752500 PMID:35537566 NCBI chr 6:83,282,686...83,302,926
Ensembl chr 6:83,282,673...83,302,890
JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like increases expression ISO Diclofenac results in increased expression of MTHFD2L mRNA CTD PMID:30723492 NCBI chr 5:91,078,704...91,169,227
Ensembl chr 5:91,078,976...91,169,227
JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 increases expression EXP Diclofenac results in increased expression of MTSS1 mRNA CTD PMID:26934552 NCBI chr15:58,813,083...58,955,805
Ensembl chr15:58,813,083...58,953,854
JBrowse link
G Mup4 major urinary protein 4 decreases expression EXP Diclofenac results in decreased expression of MUP4 mRNA CTD PMID:26934552 NCBI chr 4:59,956,804...59,960,667
Ensembl chr 4:59,956,804...59,960,710
JBrowse link
G Mvp major vault protein increases expression EXP Diclofenac results in increased expression of MVP mRNA CTD PMID:26934552 NCBI chr 7:126,586,036...126,613,729
Ensembl chr 7:126,586,032...126,613,793
JBrowse link
G Mx1 MX dynamin-like GTPase 1 decreases expression ISO Diclofenac results in decreased expression of MX1 mRNA CTD PMID:19192274 NCBI chr16:97,248,235...97,264,106
Ensembl chr16:97,248,235...97,264,107
JBrowse link
G Mxd1 MAX dimerization protein 1 affects expression ISO Diclofenac affects the expression of MXD1 mRNA CTD PMID:24752500 NCBI chr 6:86,624,026...86,646,099
Ensembl chr 6:86,624,024...86,646,143
JBrowse link
G Myc myelocytomatosis oncogene increases expression
decreases expression
affects expression
ISO
EXP
Diclofenac results in increased expression of MYC mRNA
Diclofenac results in decreased expression of MYC mRNA
Diclofenac affects the expression of MYC mRNA
CTD PMID:19022234 PMID:24752500 PMID:35537566 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
JBrowse link
G Myd88 myeloid differentiation primary response gene 88 increases expression EXP Diclofenac results in increased expression of MYD88 mRNA CTD PMID:26934552 NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477
JBrowse link
G Napepld N-acyl phosphatidylethanolamine phospholipase D affects expression ISO Diclofenac affects the expression of NAPEPLD mRNA CTD PMID:24752500 NCBI chr 5:21,867,899...21,906,620
Ensembl chr 5:21,867,899...21,906,394
JBrowse link
G Nars1 asparaginyl-tRNA synthetase 1 decreases expression EXP Diclofenac results in decreased expression of NARS1 mRNA CTD PMID:35537566 NCBI chr18:64,632,726...64,649,586
Ensembl chr18:64,632,718...64,649,723
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 increases expression EXP Diclofenac results in increased expression of NCF1 mRNA CTD PMID:26934552 NCBI chr 5:134,248,907...134,258,479
Ensembl chr 5:134,248,907...134,258,479
JBrowse link
G Ncf4 neutrophil cytosolic factor 4 increases expression EXP Diclofenac results in increased expression of NCF4 mRNA CTD PMID:26934552 NCBI chr15:78,128,324...78,146,782
Ensembl chr15:78,129,001...78,146,780
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in increased expression of NCOA1 mRNA CTD PMID:37844793 NCBI chr12:4,297,362...4,569,452
Ensembl chr12:4,297,362...4,527,182
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 affects expression ISO Diclofenac affects the expression of NCOA3 mRNA CTD PMID:24752500 NCBI chr 2:165,834,557...165,915,162
Ensembl chr 2:165,834,545...165,915,162
JBrowse link
G Ndufa7 NADH:ubiquinone oxidoreductase subunit A7 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of NDUFA7 mRNA CTD PMID:37844793 NCBI chr17:34,043,546...34,057,290
Ensembl chr17:34,043,546...34,057,291
JBrowse link
G Nedd4l neural precursor cell expressed, developmentally down-regulated gene 4-like increases expression EXP Diclofenac results in increased expression of NEDD4L mRNA CTD PMID:26934552 NCBI chr18:65,017,551...65,350,888
Ensembl chr18:65,020,776...65,350,899
JBrowse link
G Nek6 NIMA (never in mitosis gene a)-related expressed kinase 6 increases expression EXP Diclofenac results in increased expression of NEK6 mRNA CTD PMID:26934552 NCBI chr 2:38,314,052...38,477,502
Ensembl chr 2:38,401,655...38,484,618
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 increases stability
decreases expression
multiple interactions
ISO Diclofenac results in increased stability of NFE2L2 protein
Diclofenac results in decreased expression of NFE2L2 protein
diacerein inhibits the reaction [Diclofenac results in decreased expression of NFE2L2 protein]
NFE2L2 protein affects the reaction [Diclofenac results in increased expression of SRXN1 mRNA]
CTD PMID:24752500 PMID:38582345 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfil3 nuclear factor, interleukin 3, regulated increases expression
decreases expression
EXP Diclofenac results in increased expression of NFIL3 mRNA
Diclofenac results in decreased expression of NFIL3 mRNA
CTD PMID:26934552 PMID:35537566 NCBI chr13:53,121,245...53,136,914
Ensembl chr13:53,121,245...53,135,109
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions
decreases expression
ISO Diclofenac inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Diclofenac inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]
Diclofenac results in decreased expression of NFKB1 mRNA
CTD PMID:15489888 PMID:29027214 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions
decreases expression
ISO Diclofenac inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]
Diclofenac inhibits the reaction [Freund's Adjuvant results in increased phosphorylation of NFKBIA protein]; Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in decreased expression of NFKBIA protein]
Diclofenac results in decreased expression of NFKBIA mRNA
CTD PMID:15489888 PMID:18172885 PMID:19393675 PMID:25935278 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nfkbiz nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta decreases expression
increases expression
EXP Diclofenac results in decreased expression of NFKBIZ mRNA
Diclofenac results in increased expression of NFKBIZ mRNA
CTD PMID:26934552 NCBI chr16:55,631,740...55,659,018
Ensembl chr16:55,631,738...55,659,262
JBrowse link
G Ngfr nerve growth factor receptor (TNFR superfamily, member 16) increases expression EXP Diclofenac results in increased expression of TNFRSF10B mRNA CTD PMID:35537566 NCBI chr11:95,459,644...95,478,524
Ensembl chr11:95,459,644...95,478,561
JBrowse link
G Ngp neutrophilic granule protein increases expression EXP Diclofenac results in increased expression of NGP mRNA CTD PMID:26934552 NCBI chr 9:110,248,876...110,252,080
Ensembl chr 9:110,248,815...110,252,080
JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 increases expression EXP Diclofenac results in increased expression of NHERF1 mRNA CTD PMID:26934552 NCBI chr11:115,054,138...115,072,009
Ensembl chr11:115,054,167...115,072,007
JBrowse link
G Nherf2 NHERF family PDZ scaffold protein 2 decreases expression EXP Diclofenac results in decreased expression of NHERF2 mRNA CTD PMID:26934552 NCBI chr17:24,858,255...24,869,279
Ensembl chr17:24,858,260...24,869,301
JBrowse link
G Nhsl2 NHS like 2 increases expression EXP Diclofenac results in increased expression of NHSL2 mRNA CTD PMID:35537566 NCBI chr  X:100,892,942...101,135,661
Ensembl chr  X:100,892,991...101,135,661
JBrowse link
G Nipal1 NIPA-like domain containing 1 increases expression EXP Diclofenac results in increased expression of NIPAL1 mRNA CTD PMID:26934552 NCBI chr 5:72,805,139...72,828,421
Ensembl chr 5:72,805,138...72,828,421
JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A multiple interactions ISO Diclofenac inhibits the reaction [Freund's Adjuvant results in increased expression of NLRP1A protein] CTD PMID:25450234 NCBI chr11:70,982,023...71,035,780
Ensembl chr11:70,983,062...71,035,530
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression
multiple interactions
EXP
ISO
Diclofenac results in increased expression of NLRP3 mRNA
diacerein inhibits the reaction [Diclofenac results in increased expression of NLRP3 protein]
CTD PMID:24747151 PMID:28138970 PMID:38582345 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
JBrowse link
G Nnmt nicotinamide N-methyltransferase increases expression EXP Diclofenac results in increased expression of NNMT mRNA CTD PMID:26934552 NCBI chr 9:48,448,905...48,518,958
Ensembl chr 9:48,503,177...48,516,453
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions
decreases expression
increases expression
ISO
EXP
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 protein]; Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein]; Diclofenac promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 mRNA]; Diclofenac promotes the reaction [Poly I-C results in increased expression of NOS2 mRNA]; RELA mutant form inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; SN50 peptide inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; sodium nitrate inhibits the reaction [Diclofenac results in increased expression of NOS2 mRNA]
Diclofenac results in decreased expression of NOS2 mRNA
CTD PMID:15135310 PMID:16944022 PMID:17275683 PMID:19393675 PMID:23395999 More... NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nova1 NOVA alternative splicing regulator 1 decreases expression EXP Diclofenac results in decreased expression of NOVA1 mRNA CTD PMID:26934552 NCBI chr12:46,744,678...46,866,143
Ensembl chr12:46,741,300...46,865,712
JBrowse link
G Nox1 NADPH oxidase 1 decreases expression EXP Diclofenac results in decreased expression of NOX1 mRNA CTD PMID:35537566 NCBI chr  X:132,987,170...133,038,455
Ensembl chr  X:132,987,170...133,122,705
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 increases activity
multiple interactions
affects expression
increases expression
ISO Diclofenac results in increased activity of NQO1 protein
Diclofenac inhibits the reaction [NQO1 protein results in increased reduction of 2,6-Dichloroindophenol]
Diclofenac affects the expression of NQO1 mRNA
Diclofenac results in increased expression of NQO1 mRNA
CTD PMID:8572925 PMID:18172885 PMID:24752500 PMID:29281794 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 affects expression ISO Diclofenac affects the expression of NR0B2 mRNA CTD PMID:24752500 NCBI chr 4:133,280,687...133,283,997
Ensembl chr 4:133,280,687...133,283,847
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 increases expression
multiple interactions
EXP Diclofenac results in increased expression of NR1D1 mRNA
[Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in increased expression of NR1D1 mRNA
CTD PMID:35537566 PMID:37844793 NCBI chr11:98,658,758...98,666,233
Ensembl chr11:98,658,758...98,666,159
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression
increases activity
ISO Diclofenac results in increased expression of NR1I2 mRNA
Diclofenac results in increased activity of NR1I2 protein
CTD PMID:19022234 PMID:28728110 NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 affects expression ISO Diclofenac affects the expression of NR1I3 mRNA CTD PMID:19022234 NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270
JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 affects expression ISO Diclofenac affects the expression of NR2F1 mRNA CTD PMID:24752500 NCBI chr13:78,337,090...78,346,954
Ensembl chr13:78,337,092...78,347,876
JBrowse link
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 affects expression ISO Diclofenac affects the expression of NR2F2 mRNA CTD PMID:24752500 NCBI chr 7:70,001,694...70,016,494
Ensembl chr 7:70,001,692...70,016,483
JBrowse link
G Nr2f6 nuclear receptor subfamily 2, group F, member 6 affects expression ISO Diclofenac affects the expression of NR2F6 mRNA CTD PMID:24752500 NCBI chr 8:71,826,762...71,834,593
Ensembl chr 8:71,826,767...71,834,604
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects expression
multiple interactions
ISO Diclofenac affects the expression of NR3C1 mRNA
Diclofenac binds to and affects the activity of NR3C1 protein
CTD PMID:24752500 PMID:29777833 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474
JBrowse link
G Nr6a1 nuclear receptor subfamily 6, group A, member 1 affects expression ISO Diclofenac affects the expression of NR6A1 mRNA CTD PMID:24752500 NCBI chr 2:38,613,381...38,816,464
Ensembl chr 2:38,613,382...38,817,700
JBrowse link
G Nras neuroblastoma ras oncogene affects expression ISO Diclofenac affects the expression of NRAS mRNA CTD PMID:24752500 NCBI chr 3:102,965,643...102,975,230
Ensembl chr 3:102,965,601...102,975,230
JBrowse link
G Nrep neuronal regeneration related protein decreases expression EXP Diclofenac results in decreased expression of NREP mRNA CTD PMID:26934552 NCBI chr18:33,570,072...33,597,444
Ensembl chr18:33,570,072...33,597,082
JBrowse link
G Nrg4 neuregulin 4 increases expression EXP Diclofenac results in increased expression of NRG4 mRNA CTD PMID:26934552 NCBI chr 9:55,127,506...55,190,937
Ensembl chr 9:55,127,506...55,234,128
JBrowse link
G Nrp1 neuropilin 1 increases expression EXP Diclofenac results in increased expression of NRP1 mRNA CTD PMID:26934552 NCBI chr 8:129,085,553...129,231,957
Ensembl chr 8:129,085,085...129,229,844
JBrowse link
G Nt5e 5' nucleotidase, ecto increases expression EXP Diclofenac results in increased expression of NT5E mRNA CTD PMID:35537566 NCBI chr 9:88,209,662...88,254,142
Ensembl chr 9:88,209,250...88,254,145
JBrowse link
G Nupr1 nuclear protein transcription regulator 1 decreases expression EXP Diclofenac results in decreased expression of NUPR1 mRNA CTD PMID:35537566 NCBI chr 7:126,222,418...126,224,642
Ensembl chr 7:126,222,421...126,230,033
JBrowse link
G Nxpe4 neurexophilin and PC-esterase domain family, member 4 increases expression EXP Diclofenac results in increased expression of NXPE4 mRNA CTD PMID:26934552 NCBI chr 9:48,073,302...48,311,325
Ensembl chr 9:48,073,321...48,311,325
JBrowse link
G Oas1g 2'-5' oligoadenylate synthetase 1G decreases expression ISO Diclofenac results in decreased expression of OAS1 mRNA CTD PMID:19192274 NCBI chr 5:121,014,205...121,025,676
Ensembl chr 5:121,014,205...121,025,676
JBrowse link
G Oca2 oculocutaneous albinism II multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of OCA2 mRNA CTD PMID:37844793 NCBI chr 7:55,889,341...56,186,266
Ensembl chr 7:55,889,508...56,186,266
JBrowse link
G Ocln occludin decreases expression ISO Diclofenac results in decreased expression of OCLN mRNA CTD PMID:29027214 NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
JBrowse link
G Olfml2b olfactomedin-like 2B increases expression ISO Diclofenac results in increased expression of OLFML2B mRNA CTD PMID:19192274 NCBI chr 1:170,472,101...170,510,356
Ensembl chr 1:170,472,101...170,510,358
JBrowse link
G Omt2a oocyte maturation, alpha multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of OMT2A mRNA CTD PMID:37844793 NCBI chr 9:78,219,254...78,222,079
Ensembl chr 9:78,219,254...78,222,078
JBrowse link
G Ooep oocyte expressed protein multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of OOEP mRNA CTD PMID:37844793 NCBI chr 9:78,284,185...78,285,870
Ensembl chr 9:78,283,391...78,286,007
JBrowse link
G Oosp1 oocyte secreted protein 1 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of OOSP1 mRNA CTD PMID:37844793 NCBI chr19:11,644,824...11,668,415
Ensembl chr19:11,644,824...11,668,514
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase decreases expression
multiple interactions
EXP
ISO
Diclofenac results in decreased expression of OPA1 mRNA
AICA ribonucleotide inhibits the reaction [Diclofenac results in decreased expression of OPA1 protein]
CTD PMID:26934552 PMID:27792760 NCBI chr16:29,398,099...29,481,924
Ensembl chr16:29,398,152...29,473,702
JBrowse link
G Opcml opioid binding protein/cell adhesion molecule-like increases expression EXP Diclofenac results in increased expression of OPCML mRNA CTD PMID:26934552 NCBI chr 9:27,702,050...28,836,706
Ensembl chr 9:27,702,071...28,836,706
JBrowse link
G Or8d1b olfactory receptor family 8 subfamily D member 1B decreases expression EXP Diclofenac results in decreased expression of OR8D1B mRNA CTD PMID:35537566 NCBI chr 9:38,886,974...38,887,900
Ensembl chr 9:38,883,609...38,891,157
JBrowse link
G Orm1 orosomucoid 1 multiple interactions
increases expression
ISO
EXP
[Diclofenac co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ORM1 protein
Diclofenac results in increased expression of ORM1 mRNA
CTD PMID:25772430 PMID:26934552 NCBI chr 4:63,262,793...63,266,400
Ensembl chr 4:63,262,797...63,266,400
JBrowse link
G Orm2 orosomucoid 2 increases expression EXP Diclofenac results in increased expression of ORM2 mRNA CTD PMID:26934552 NCBI chr 4:63,280,543...63,284,114
Ensembl chr 4:63,280,686...63,284,115
JBrowse link
G Orm3 orosomucoid 3 increases expression EXP Diclofenac results in increased expression of ORM3 mRNA CTD PMID:26934552 NCBI chr 4:63,274,107...63,277,748
Ensembl chr 4:63,274,399...63,277,748
JBrowse link
G Oxtr oxytocin receptor multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in increased expression of OXTR mRNA CTD PMID:37844793 NCBI chr 6:112,450,646...112,467,800
Ensembl chr 6:112,450,644...112,466,904
JBrowse link
G P2rx4 purinergic receptor P2X, ligand-gated ion channel 4 multiple interactions ISO Diclofenac inhibits the reaction [Freund's Adjuvant results in increased expression of P2RX4 protein] CTD PMID:25450234 NCBI chr 5:122,845,581...122,867,802
Ensembl chr 5:122,845,607...122,867,801
JBrowse link
G P2rx5 purinergic receptor P2X, ligand-gated ion channel, 5 increases expression ISO Diclofenac results in increased expression of P2RX5 mRNA CTD PMID:30723492 NCBI chr11:73,029,164...73,063,509
Ensembl chr11:73,051,247...73,063,511
JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 multiple interactions
increases expression
ISO
EXP
Diclofenac inhibits the reaction [Freund's Adjuvant results in increased expression of P2RX7 protein]
Diclofenac results in increased expression of P2RX7 mRNA
CTD PMID:25935278 PMID:26934552 NCBI chr 5:122,781,990...122,830,399
Ensembl chr 5:122,781,974...122,829,495
JBrowse link
G P4ha2 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide increases expression ISO Diclofenac results in increased expression of P4HA2 mRNA CTD PMID:17379860 NCBI chr11:53,991,750...54,022,494
Ensembl chr11:53,990,921...54,022,491
JBrowse link
G P4hb prolyl 4-hydroxylase, beta polypeptide multiple interactions
increases expression
ISO [Diclofenac co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of P4HB protein
Diclofenac results in increased expression of P4HB protein
CTD PMID:25772430 NCBI chr11:120,451,124...120,464,079
Ensembl chr11:120,451,124...120,464,079
JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 affects expression ISO Diclofenac affects the expression of PAK2 mRNA CTD PMID:24752500 NCBI chr16:31,835,108...31,898,160
Ensembl chr16:31,835,108...31,898,160
JBrowse link
G Paqr8 progestin and adipoQ receptor family member VIII increases expression ISO Diclofenac results in increased expression of PAQR8 mRNA CTD PMID:30723492 NCBI chr 1:20,960,772...21,009,874
Ensembl chr 1:20,960,830...21,009,874
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 affects expression ISO Diclofenac affects the expression of PARP1 mRNA CTD PMID:24752500 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pax6 paired box 6 increases expression EXP Diclofenac results in increased expression of PAX6 mRNA CTD PMID:26934552 NCBI chr 2:105,499,241...105,528,755
Ensembl chr 2:105,499,245...105,527,709
JBrowse link
G Pcdhga8 protocadherin gamma subfamily A, 8 increases expression ISO Diclofenac results in increased expression of PCDHGA8 mRNA CTD PMID:30723492 NCBI chr18:37,858,759...37,974,926
Ensembl chr18:37,858,759...37,974,926
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic affects expression ISO Diclofenac affects the expression of PCK1 mRNA CTD PMID:24752500 NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) decreases expression EXP Diclofenac results in decreased expression of PCK2 mRNA CTD PMID:35537566 NCBI chr14:55,777,721...55,787,477
Ensembl chr14:55,777,723...55,788,699
JBrowse link
G Pcna proliferating cell nuclear antigen affects expression ISO Diclofenac affects the expression of PCNA protein CTD PMID:23506792 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 increases expression EXP Diclofenac results in increased expression of PCSK9 mRNA CTD PMID:26934552 NCBI chr 4:106,299,531...106,321,522
Ensembl chr 4:106,299,526...106,321,526
JBrowse link
G Pdcd4 programmed cell death 4 decreases expression
increases expression
ISO Diclofenac results in decreased expression of PDCD4 mRNA
Diclofenac results in increased expression of PDCD4 mRNA
CTD PMID:21873647 NCBI chr19:53,880,662...53,926,024
Ensembl chr19:53,880,662...53,918,291
JBrowse link
G Pde9a phosphodiesterase 9A increases expression ISO Diclofenac results in increased expression of PDE9A mRNA CTD PMID:30723492 NCBI chr17:31,605,079...31,695,284
Ensembl chr17:31,605,184...31,695,284
JBrowse link
G Pdgfrb platelet derived growth factor receptor, beta polypeptide decreases expression EXP Diclofenac results in decreased expression of PDGFRB mRNA CTD PMID:26934552 NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133
JBrowse link
G Pdia6 protein disulfide isomerase associated 6 increases expression EXP Diclofenac results in increased expression of PDIA6 mRNA CTD PMID:26934552 NCBI chr12:17,316,590...17,334,786
Ensembl chr12:17,316,546...17,334,771
JBrowse link
G Pdilt protein disulfide isomerase-like, testis expressed decreases expression EXP Diclofenac results in decreased expression of PDILT mRNA CTD PMID:26934552 NCBI chr 7:119,085,809...119,128,259
Ensembl chr 7:119,085,810...119,122,712
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase, isoenzyme 4 decreases expression EXP Diclofenac results in decreased expression of PDK4 mRNA CTD PMID:26934552 NCBI chr 6:5,483,351...5,496,278
Ensembl chr 6:5,483,351...5,496,309
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 affects expression ISO Diclofenac affects the expression of PDPK1 mRNA CTD PMID:24752500 NCBI chr17:24,292,654...24,370,957
Ensembl chr17:24,292,654...24,369,898
JBrowse link
G Pfkl phosphofructokinase, liver, B-type multiple interactions EXP [Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in increased expression of PFKL mRNA; Sodium Selenite inhibits the reaction [[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in increased expression of PFKL mRNA] CTD PMID:38945390 NCBI chr10:77,822,781...77,845,641
Ensembl chr10:77,822,781...77,845,917
JBrowse link
G Pgk2 phosphoglycerate kinase 2 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of PGK2 mRNA CTD PMID:37844793 NCBI chr17:40,517,909...40,519,500
Ensembl chr17:40,517,906...40,519,531
JBrowse link
G Phf10 PHD finger protein 10 decreases expression EXP Diclofenac results in decreased expression of PHF10 mRNA CTD PMID:35537566 NCBI chr17:15,165,269...15,181,550
Ensembl chr17:15,165,271...15,181,535
JBrowse link
G Phlda1 pleckstrin homology like domain, family A, member 1 decreases expression EXP Diclofenac results in decreased expression of PHLDA1 mRNA CTD PMID:26934552 NCBI chr10:111,342,147...111,344,510
Ensembl chr10:111,342,147...111,344,506
JBrowse link
G Phlda3 pleckstrin homology like domain, family A, member 3 increases expression EXP Diclofenac results in increased expression of PHLDA3 mRNA CTD PMID:35537566 NCBI chr 1:135,693,823...135,696,872
Ensembl chr 1:135,693,857...135,696,874
JBrowse link
G Phyhipl phytanoyl-CoA hydroxylase interacting protein-like decreases expression EXP Diclofenac results in decreased expression of PHYHIPL mRNA CTD PMID:26934552 NCBI chr10:70,393,516...70,435,121
Ensembl chr10:70,393,512...70,491,795
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression ISO Diclofenac results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 1:84,014,014...84,317,550
Ensembl chr 1:84,014,017...84,341,901
JBrowse link
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha affects expression ISO Diclofenac affects the expression of PIK3C2A mRNA CTD PMID:24752500 NCBI chr 7:115,936,500...116,042,693
Ensembl chr 7:115,936,500...116,042,684
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha affects expression ISO Diclofenac affects the expression of PIK3CA mRNA CTD PMID:24752500 NCBI chr 3:32,451,203...32,520,256
Ensembl chr 3:32,451,820...32,522,635
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta affects expression ISO Diclofenac affects the expression of PIK3CD mRNA CTD PMID:24752500 NCBI chr 4:149,733,625...149,787,023
Ensembl chr 4:149,733,625...149,787,028
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 affects expression
increases expression
ISO
EXP
Diclofenac affects the expression of PIK3R1 mRNA
Diclofenac results in increased expression of PIK3R1 mRNA
CTD PMID:24752500 PMID:26934552 NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725
JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 affects expression ISO Diclofenac affects the expression of PIK3R2 mRNA CTD PMID:24752500 NCBI chr 8:71,220,820...71,229,356
Ensembl chr 8:71,220,820...71,229,357
JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 affects expression ISO Diclofenac affects the expression of PIK3R3 mRNA CTD PMID:24752500 NCBI chr 4:116,078,593...116,160,253
Ensembl chr 4:116,078,815...116,160,253
Ensembl chr 4:116,078,815...116,160,253
JBrowse link
G Pirb paired Ig-like receptor B increases expression EXP
ISO
Diclofenac results in increased expression of PIRB mRNA CTD PMID:26934552 PMID:30723492 NCBI chr 7:3,715,504...3,723,381
Ensembl chr 7:3,714,408...3,723,390
JBrowse link
G Pklr pyruvate kinase liver and red blood cell increases expression
multiple interactions
EXP Diclofenac results in increased expression of PKLR mRNA
[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in decreased expression of PKLR mRNA; Sodium Selenite promotes the reaction [[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in decreased expression of PKLR mRNA]
CTD PMID:26934552 PMID:38945390 NCBI chr 3:89,043,429...89,054,122
Ensembl chr 3:89,043,449...89,054,091
JBrowse link
G Pknox2 Pbx/knotted 1 homeobox 2 increases expression ISO Diclofenac results in increased expression of PKNOX2 mRNA CTD PMID:30723492 NCBI chr 9:36,802,278...37,058,637
Ensembl chr 9:36,802,278...37,058,703
JBrowse link
G Pla2g12a phospholipase A2, group XIIA affects expression ISO Diclofenac affects the expression of PLA2G12A mRNA CTD PMID:24752500 NCBI chr 3:129,672,255...129,689,474
Ensembl chr 3:129,672,255...129,689,474
JBrowse link
G Pla2g4c phospholipase A2, group IVC (cytosolic, calcium-independent) increases expression EXP Diclofenac results in increased expression of PLA2G4C mRNA CTD PMID:26934552 NCBI chr 7:13,045,432...13,094,597
Ensembl chr 7:13,058,580...13,094,597
JBrowse link
G Pla2g7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) increases expression EXP Diclofenac results in increased expression of PLA2G7 mRNA CTD PMID:26934552 NCBI chr17:43,879,009...43,923,093
Ensembl chr17:43,878,989...43,923,092
JBrowse link
G Plac8 placenta-specific 8 increases expression EXP Diclofenac results in increased expression of PLAC8 mRNA CTD PMID:26934552 NCBI chr 5:100,699,455...100,720,119
Ensembl chr 5:100,701,591...100,720,111
JBrowse link
G Plau plasminogen activator, urokinase increases expression
decreases expression
EXP Diclofenac results in increased expression of PLAU protein
Diclofenac results in decreased expression of PLAU mRNA
CTD PMID:23506792 PMID:35537566 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453
JBrowse link
G Plcg1 phospholipase C, gamma 1 affects expression ISO Diclofenac affects the expression of PLCG1 mRNA CTD PMID:24752500 NCBI chr 2:160,573,230...160,617,680
Ensembl chr 2:160,573,220...160,617,680
JBrowse link
G Pld1 phospholipase D1 increases expression EXP Diclofenac results in increased expression of PLD1 mRNA CTD PMID:26934552 NCBI chr 3:27,992,636...28,187,388
Ensembl chr 3:27,992,844...28,187,511
JBrowse link
G Plekhh2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 decreases expression EXP Diclofenac results in decreased expression of PLEKHH2 mRNA CTD PMID:35537566 NCBI chr17:84,819,303...84,929,571
Ensembl chr17:84,819,323...84,929,566
JBrowse link
G Plk3 polo like kinase 3 affects expression EXP Diclofenac affects the expression of PLK3 mRNA CTD PMID:26934552 NCBI chr 4:116,985,852...116,991,244
Ensembl chr 4:116,985,852...116,991,160
JBrowse link
G Plscr1 phospholipid scramblase 1 increases expression EXP Diclofenac results in increased expression of PLSCR1 mRNA CTD PMID:26934552 NCBI chr 9:92,132,265...92,154,034
Ensembl chr 9:92,131,803...92,154,331
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression EXP Diclofenac results in increased expression of PMAIP1 mRNA CTD PMID:26934552 NCBI chr18:66,591,675...66,598,629
Ensembl chr18:66,591,604...66,598,636
JBrowse link
G Pnliprp2 pancreatic lipase-related protein 2 increases expression EXP Diclofenac results in increased expression of PNLIPRP2 mRNA CTD PMID:26934552 NCBI chr19:58,748,155...58,765,966
Ensembl chr19:58,748,151...58,765,966
JBrowse link
G Pole3 polymerase (DNA directed), epsilon 3 (p17 subunit) affects expression ISO Diclofenac affects the expression of POLE3 mRNA CTD PMID:24752500 NCBI chr 4:62,440,889...62,443,305
Ensembl chr 4:62,440,886...62,443,305
JBrowse link
G Pole4 polymerase (DNA-directed), epsilon 4 (p12 subunit) affects expression ISO Diclofenac affects the expression of POLE4 mRNA CTD PMID:24752500 NCBI chr 6:82,593,513...82,629,985
Ensembl chr 6:82,595,973...82,682,346
JBrowse link
G Polg polymerase (DNA directed), gamma affects expression ISO Diclofenac affects the expression of POLG mRNA CTD PMID:24752500 NCBI chr 7:79,095,979...79,117,659
Ensembl chr 7:79,095,979...79,116,110
JBrowse link
G Polh polymerase (DNA directed), eta (RAD 30 related) affects expression ISO Diclofenac affects the expression of POLH mRNA CTD PMID:24752500 NCBI chr17:46,482,281...46,513,567
Ensembl chr17:46,482,281...46,513,571
JBrowse link
G Polq polymerase (DNA directed), theta affects expression ISO Diclofenac affects the expression of POLQ mRNA CTD PMID:24752500 NCBI chr16:36,832,104...36,922,321
Ensembl chr16:36,832,148...36,915,779
JBrowse link
G Polr2f polymerase (RNA) II (DNA directed) polypeptide F affects expression ISO Diclofenac affects the expression of POLR2F mRNA CTD PMID:24752500 NCBI chr15:79,025,525...79,035,974
Ensembl chr15:79,025,209...79,035,974
JBrowse link
G Polr3a polymerase (RNA) III (DNA directed) polypeptide A affects expression ISO Diclofenac affects the expression of POLR3A mRNA CTD PMID:24752500 NCBI chr14:24,498,762...24,537,126
Ensembl chr14:24,498,764...24,537,126
JBrowse link
G Polr3d polymerase (RNA) III (DNA directed) polypeptide D affects expression ISO Diclofenac affects the expression of POLR3D mRNA CTD PMID:24752500 NCBI chr14:70,676,188...70,680,911
Ensembl chr14:70,676,197...70,680,887
JBrowse link
G Polr3g polymerase (RNA) III (DNA directed) polypeptide G increases expression EXP Diclofenac results in increased expression of POLR3G mRNA CTD PMID:35537566 NCBI chr13:81,821,956...81,859,132
Ensembl chr13:81,821,962...81,859,132
JBrowse link
G Pomk protein-O-mannose kinase increases expression EXP Diclofenac results in increased expression of POMK mRNA CTD PMID:26934552 NCBI chr 8:26,470,632...26,484,149
Ensembl chr 8:26,470,632...26,484,161
JBrowse link
G Pon1 paraoxonase 1 multiple interactions ISO [pyrrolidine analog binds to Palladium binds to Diclofenac] which results in decreased activity of PON1 protein; [pyrrolidine analog binds to Platinum binds to Diclofenac] which results in decreased activity of PON1 protein CTD PMID:29512227 NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946
JBrowse link
G Por cytochrome p450 oxidoreductase affects response to substance
increases oxidation
EXP POR affects the susceptibility to Diclofenac
POR results in increased oxidation of Diclofenac
CTD PMID:25820915 NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180
JBrowse link
G Pou2af1 POU domain, class 2, associating factor 1 decreases expression EXP Diclofenac results in decreased expression of POU2AF1 mRNA CTD PMID:26934552 NCBI chr 9:51,124,990...51,151,379
Ensembl chr 9:51,125,008...51,151,380
JBrowse link
G Pou2f1 POU domain, class 2, transcription factor 1 affects expression ISO Diclofenac affects the expression of POU2F1 mRNA CTD PMID:24752500 NCBI chr 1:165,692,719...165,830,318
Ensembl chr 1:165,692,723...165,830,247
JBrowse link
G Pou2f2 POU domain, class 2, transcription factor 2 increases expression EXP Diclofenac results in increased expression of POU2F2 mRNA CTD PMID:26934552 NCBI chr 7:24,790,111...24,879,292
Ensembl chr 7:24,786,769...24,879,151
JBrowse link
G Pou2f3 POU domain, class 2, transcription factor 3 increases expression EXP Diclofenac results in increased expression of POU2F3 mRNA CTD PMID:26934552 NCBI chr 9:43,035,222...43,117,052
Ensembl chr 9:43,035,234...43,121,666
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma affects expression
multiple interactions
increases activity
ISO Diclofenac affects the expression of PPARG mRNA
Diclofenac inhibits the reaction [Rosiglitazone results in increased activity of PPARG protein]
Diclofenac results in increased activity of PPARG protein
CTD PMID:12065695 PMID:15273253 PMID:24752500 PMID:28728110 PMID:30138673 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha affects expression
increases expression
ISO
EXP
Diclofenac affects the expression of PPARGC1A mRNA
Diclofenac results in increased expression of PPARGC1A mRNA
CTD PMID:24752500 PMID:26934552 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Ppargc1b peroxisome proliferative activated receptor, gamma, coactivator 1 beta decreases expression EXP Diclofenac results in decreased expression of PPARGC1B mRNA CTD PMID:26934552 NCBI chr18:61,424,516...61,533,846
Ensembl chr18:61,431,207...61,533,502
JBrowse link
G Ppbp pro-platelet basic protein increases expression EXP Diclofenac results in increased expression of PPBP mRNA CTD PMID:26934552 NCBI chr 5:90,916,377...90,917,922
Ensembl chr 5:90,916,377...90,917,922
JBrowse link
G Ppif peptidylprolyl isomerase F (cyclophilin F) increases response to substance EXP PPIF results in increased susceptibility to Diclofenac CTD PMID:20668000 NCBI chr14:25,693,998...25,700,892
Ensembl chr14:25,694,578...25,700,892
JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta affects expression ISO Diclofenac affects the expression of PPP1CB mRNA CTD PMID:24752500 NCBI chr 5:32,616,192...32,651,057
Ensembl chr 5:32,616,187...32,674,777
JBrowse link
G Ppp1r14b protein phosphatase 1, regulatory inhibitor subunit 14B affects expression ISO Diclofenac affects the expression of PPP1R14B mRNA CTD PMID:24752500 NCBI chr19:6,952,416...6,954,692
Ensembl chr19:6,952,336...6,954,692
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A affects expression
decreases expression
ISO
EXP
Diclofenac affects the expression of PPP1R15A mRNA
Diclofenac results in decreased expression of PPP1R15A mRNA
CTD PMID:24752500 PMID:35537566 NCBI chr 7:45,172,341...45,175,692
Ensembl chr 7:45,172,340...45,175,692
JBrowse link
G Ppp1r7 protein phosphatase 1, regulatory subunit 7 affects expression ISO Diclofenac affects the expression of PPP1R7 mRNA CTD PMID:24752500 NCBI chr 1:93,271,350...93,295,344
Ensembl chr 1:93,270,576...93,301,211
JBrowse link
G Ppp2r1b protein phosphatase 2, regulatory subunit A, beta affects expression ISO Diclofenac affects the expression of PPP2R1B mRNA CTD PMID:24752500 NCBI chr 9:50,767,946...50,810,625
Ensembl chr 9:50,756,601...50,805,529
JBrowse link
G Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha affects expression ISO Diclofenac affects the expression of PPP2R2A mRNA CTD PMID:24752500 NCBI chr14:67,251,505...67,309,920
Ensembl chr14:67,251,505...67,309,893
JBrowse link
G Ppp2r2c protein phosphatase 2, regulatory subunit B, gamma affects expression ISO Diclofenac affects the expression of PPP2R2C mRNA CTD PMID:24752500 NCBI chr 5:37,024,187...37,112,422
Ensembl chr 5:37,025,857...37,112,422
JBrowse link
G Ppp2r5a protein phosphatase 2, regulatory subunit B', alpha affects expression ISO Diclofenac affects the expression of PPP2R5A mRNA CTD PMID:24752500 NCBI chr 1:191,084,178...191,129,238
Ensembl chr 1:191,084,172...191,135,469
JBrowse link
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma affects expression ISO Diclofenac affects the expression of PPP2R5C mRNA CTD PMID:24752500 NCBI chr12:110,413,532...110,549,509
Ensembl chr12:110,413,554...110,549,496
JBrowse link
G Prdm1 PR domain containing 1, with ZNF domain decreases expression EXP Diclofenac results in decreased expression of PRDM1 mRNA CTD PMID:35537566 NCBI chr10:44,313,170...44,404,579
Ensembl chr10:44,313,173...44,404,497
JBrowse link
G Prg4 proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein) increases expression EXP Diclofenac results in increased expression of PRG4 mRNA CTD PMID:26934552 NCBI chr 1:150,325,163...150,341,916
Ensembl chr 1:150,325,163...150,341,916
JBrowse link
G Prkacb protein kinase, cAMP dependent, catalytic, beta affects expression ISO Diclofenac affects the expression of PRKACB mRNA CTD PMID:24752500 NCBI chr 3:146,435,334...146,518,691
Ensembl chr 3:146,435,329...146,518,745
JBrowse link
G Prkca protein kinase C, alpha affects expression ISO Diclofenac affects the expression of PRKCA mRNA CTD PMID:24752500 NCBI chr11:107,824,213...108,237,360
Ensembl chr11:107,824,213...108,234,754
JBrowse link
G Prkci protein kinase C, iota affects expression ISO Diclofenac affects the expression of PRKCI mRNA CTD PMID:24752500 NCBI chr 3:31,049,893...31,106,889
Ensembl chr 3:31,049,896...31,107,108
JBrowse link
G Prkd3 protein kinase D3 affects expression ISO Diclofenac affects the expression of PRKD3 mRNA CTD PMID:24752500 NCBI chr17:79,256,834...79,328,245
Ensembl chr17:79,256,834...79,328,245
JBrowse link
G Prkg2 protein kinase, cGMP-dependent, type II decreases expression EXP Diclofenac results in decreased expression of PRKG2 mRNA CTD PMID:35537566 NCBI chr 5:99,077,632...99,185,042
Ensembl chr 5:99,077,632...99,185,210
JBrowse link
G Prl prolactin decreases expression EXP Diclofenac results in decreased expression of PRL mRNA CTD PMID:26934552 NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188
JBrowse link
G Prm1 protamine 1 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of PRM1 mRNA CTD PMID:37844793 NCBI chr16:10,614,196...10,614,687
Ensembl chr16:10,614,190...10,623,703
JBrowse link
G Procr protein C receptor, endothelial increases expression EXP Diclofenac results in increased expression of PROCR mRNA CTD PMID:26934552 NCBI chr 2:155,592,159...155,597,391
Ensembl chr 2:155,593,037...155,597,391
JBrowse link
G Prok2 prokineticin 2 increases expression EXP Diclofenac results in increased expression of PROK2 mRNA CTD PMID:26934552 NCBI chr 6:99,687,833...99,703,368
Ensembl chr 6:99,688,260...99,703,353
JBrowse link
G Pros1 protein S (alpha) increases expression EXP Diclofenac results in increased expression of PROS1 mRNA CTD PMID:26934552 NCBI chr16:62,674,670...62,749,709
Ensembl chr16:62,674,670...62,749,709
JBrowse link
G Prtn3 proteinase 3 increases expression EXP Diclofenac results in increased expression of PRTN3 mRNA CTD PMID:26934552 NCBI chr10:79,715,499...79,719,008
Ensembl chr10:79,710,310...79,719,008
JBrowse link
G Psat1 phosphoserine aminotransferase 1 affects expression ISO Diclofenac affects the expression of PSAT1 mRNA CTD PMID:24752500 NCBI chr19:15,882,487...15,902,423
Ensembl chr19:15,882,042...15,924,701
JBrowse link
G Psmb4 proteasome (prosome, macropain) subunit, beta type 4 decreases expression ISO Diclofenac results in decreased expression of PSMB4 mRNA CTD PMID:18172885 NCBI chr 3:94,791,635...94,794,269
Ensembl chr 3:94,791,404...94,794,272
JBrowse link
G Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 increases expression EXP Diclofenac results in increased expression of PSMD2 mRNA CTD PMID:26934552 NCBI chr16:20,469,872...20,482,164
Ensembl chr16:20,470,402...20,482,164
JBrowse link
G Psmd9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 decreases expression EXP Diclofenac results in decreased expression of PSMD9 mRNA CTD PMID:26934552 NCBI chr 5:123,366,253...123,388,189
Ensembl chr 5:123,307,476...123,388,194
JBrowse link
G Psmf1 proteasome (prosome, macropain) inhibitor subunit 1 affects expression ISO Diclofenac affects the expression of PSMF1 mRNA CTD PMID:24752500 NCBI chr 2:151,557,982...151,586,114
Ensembl chr 2:151,557,732...151,586,106
JBrowse link
G Pten phosphatase and tensin homolog affects expression
increases expression
ISO
EXP
Diclofenac affects the expression of PTEN mRNA
Diclofenac results in increased expression of PTEN mRNA
CTD PMID:24752500 PMID:26934552 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
JBrowse link
G Ptges prostaglandin E synthase decreases expression
multiple interactions
ISO Diclofenac results in decreased expression of PTGES mRNA
[Diclofenac results in decreased expression of PTGES mRNA] which results in decreased abundance of Dinoprostone
CTD PMID:19393675 NCBI chr 2:30,779,483...30,793,309
Ensembl chr 2:30,779,483...30,819,875
JBrowse link
G Ptges2 prostaglandin E synthase 2 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of PTGES2 mRNA CTD PMID:37844793 NCBI chr 2:32,285,902...32,292,752
Ensembl chr 2:32,285,908...32,295,784
JBrowse link
G Ptgfr prostaglandin F receptor decreases expression EXP Diclofenac results in decreased expression of PTGFR mRNA CTD PMID:26934552 NCBI chr 3:151,504,247...151,543,165
Ensembl chr 3:151,502,139...151,543,267
JBrowse link
G Ptgis prostaglandin I2 (prostacyclin) synthase multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of PTGIS mRNA CTD PMID:37844793 NCBI chr 2:167,045,114...167,095,069
Ensembl chr 2:167,033,725...167,082,524
JBrowse link
G Ptgr1 prostaglandin reductase 1 decreases activity ISO Diclofenac results in decreased activity of PTGR1 protein CTD PMID:25619643 NCBI chr 4:58,965,590...58,987,131
Ensembl chr 4:58,965,439...58,987,119
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases activity
decreases expression
multiple interactions
increases expression
ISO
EXP
Diclofenac analog results in decreased activity of PTGS1 protein; Diclofenac results in decreased activity of PTGS1 protein
Diclofenac results in decreased expression of PTGS1 protein
[thymoquinone co-treated with Diclofenac] results in decreased expression of PTGS1 protein
Diclofenac results in increased expression of PTGS1 mRNA
CTD PMID:9258749 PMID:12242329 PMID:16141368 PMID:19031110 PMID:26934552 More... NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression
increases expression
decreases activity
ISO
EXP
Diclofenac inhibits the reaction [IL1B protein results in increased activity of PTGS2 protein]; Diclofenac inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]
Diclofenac results in decreased expression of PTGS2 mRNA
Diclofenac results in increased expression of PTGS2 mRNA
Diclofenac promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 mRNA]
Diclofenac results in decreased activity of PTGS2 protein
Diclofenac results in increased expression of PTGS2 mRNA; Diclofenac results in increased expression of PTGS2 protein
Acetaminophen inhibits the reaction [Diclofenac results in increased expression of PTGS2 protein]; Diclofenac binds to and results in decreased activity of PTGS2 protein; Diclofenac inhibits the reaction [Freund's Adjuvant results in increased expression of PTGS2 protein]
CTD PMID:9258749 PMID:9851595 PMID:10594327 PMID:12242329 PMID:12925531 More... NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 affects expression ISO Diclofenac affects the expression of PTK2 mRNA CTD PMID:24752500 NCBI chr15:73,076,951...73,297,192
Ensembl chr15:73,076,951...73,295,129
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 increases expression EXP Diclofenac results in increased expression of PTPN1 mRNA CTD PMID:26934552 NCBI chr 2:167,772,670...167,821,305
Ensembl chr 2:167,773,977...167,821,305
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 increases expression EXP Diclofenac results in increased expression of PTPN2 mRNA CTD PMID:26934552 NCBI chr18:67,798,571...67,857,697
Ensembl chr18:67,798,581...67,857,665
JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C increases expression EXP Diclofenac results in increased expression of PTPRC mRNA CTD PMID:26934552 NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446
JBrowse link
G Ptprj protein tyrosine phosphatase receptor type J increases expression EXP Diclofenac results in increased expression of PTPRJ mRNA CTD PMID:26934552 NCBI chr 2:90,260,100...90,411,102
Ensembl chr 2:90,260,098...90,410,991
JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO Diclofenac inhibits the reaction [Freund's Adjuvant results in increased expression of PYCARD protein] CTD PMID:25450234 NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039
JBrowse link
G Qsox1 quiescin Q6 sulfhydryl oxidase 1 increases expression EXP Diclofenac results in increased expression of QSOX1 mRNA CTD PMID:26934552 NCBI chr 1:155,653,901...155,688,645
Ensembl chr 1:155,651,775...155,688,635
JBrowse link
G Rab11fip3 RAB11 family interacting protein 3 (class II) increases expression EXP Diclofenac results in increased expression of RAB11FIP3 mRNA CTD PMID:26934552 NCBI chr17:26,208,010...26,289,010
Ensembl chr17:26,208,010...26,288,529
JBrowse link
G Rab26os RAB26, member RAS oncogene family, opposite strand increases expression EXP Diclofenac results in increased expression of RAB26OS mRNA CTD PMID:35537566 NCBI chr17:24,747,225...24,747,718
Ensembl chr17:24,747,178...24,747,726
JBrowse link
G Rabl2 RAB, member RAS oncogene family-like 2 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of RABL2 mRNA CTD PMID:37844793 NCBI chr15:89,466,730...89,476,126
Ensembl chr15:89,466,736...89,476,126
JBrowse link
G Rack1 receptor for activated C kinase 1 affects expression ISO Diclofenac affects the expression of RACK1 mRNA CTD PMID:24752500 NCBI chr11:48,691,187...48,697,068
Ensembl chr11:48,691,159...48,697,261
JBrowse link
G Rad50 RAD50 double strand break repair protein affects expression ISO Diclofenac affects the expression of RAD50 mRNA CTD PMID:24752500 NCBI chr11:53,540,346...53,598,146
Ensembl chr11:53,540,346...53,598,146
JBrowse link
G Rad51 RAD51 recombinase affects expression
increases expression
ISO Diclofenac affects the expression of RAD51 mRNA
Diclofenac results in increased expression of RAD51 mRNA
CTD PMID:24752500 PMID:30723492 NCBI chr 2:118,943,295...118,966,554
Ensembl chr 2:118,943,274...118,977,926
JBrowse link
G Raet1d retinoic acid early transcript delta decreases expression EXP Diclofenac results in decreased expression of RAET1D mRNA CTD PMID:26934552 NCBI chr10:22,181,145...22,250,042
Ensembl chr10:22,236,451...22,250,038
JBrowse link
G Rasa1 RAS p21 protein activator 1 affects expression ISO Diclofenac affects the expression of RASA1 mRNA CTD PMID:24752500 NCBI chr13:85,362,893...85,437,487
Ensembl chr13:85,362,899...85,437,249
JBrowse link
G Rasgef1b RasGEF domain family, member 1B decreases expression EXP Diclofenac results in decreased expression of RASGEF1B mRNA CTD PMID:35537566 NCBI chr 5:99,365,279...99,400,786
Ensembl chr 5:99,365,285...99,876,924
JBrowse link
G Rb1 RB transcriptional corepressor 1 affects expression ISO Diclofenac affects the expression of RB1 mRNA CTD PMID:24752500 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262
JBrowse link
G Rbbp8 retinoblastoma binding protein 8, endonuclease increases expression
decreases expression
EXP Diclofenac results in increased expression of RBBP8 mRNA
Diclofenac results in decreased expression of RBBP8 mRNA
CTD PMID:26934552 PMID:35537566 NCBI chr18:11,766,333...11,876,264
Ensembl chr18:11,766,333...11,878,278
JBrowse link
G Rbm3 RNA binding motif (RNP1, RRM) protein 3 increases expression EXP Diclofenac results in increased expression of RBM3 mRNA CTD PMID:26934552 NCBI chr  X:8,005,214...8,012,119
Ensembl chr  X:8,005,214...8,012,119
JBrowse link
G Rbx1 ring-box 1 decreases expression EXP Diclofenac results in decreased expression of RBX1 mRNA CTD PMID:26934552 NCBI chr15:81,350,517...81,360,570
Ensembl chr15:81,350,497...81,360,570
JBrowse link
G Rcan1 regulator of calcineurin 1 decreases expression EXP Diclofenac results in decreased expression of RCAN1 mRNA CTD PMID:35537566 NCBI chr16:92,188,839...92,263,057
Ensembl chr16:92,188,841...92,267,755
JBrowse link
G Reep6 receptor accessory protein 6 increases expression EXP Diclofenac results in increased expression of REEP6 mRNA CTD PMID:35537566 NCBI chr10:80,165,831...80,172,275
Ensembl chr10:80,165,787...80,172,275
JBrowse link
G Reg3b regenerating islet-derived 3 beta increases expression EXP Diclofenac results in increased expression of REG3B mRNA CTD PMID:26934552 NCBI chr 6:78,347,868...78,350,449
Ensembl chr 6:78,347,640...78,350,449
JBrowse link
G Reg3g regenerating islet-derived 3 gamma increases expression EXP Diclofenac results in increased expression of REG3G mRNA CTD PMID:26934552 NCBI chr 6:78,443,252...78,445,857
Ensembl chr 6:78,443,252...78,445,855
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions
increases expression
affects expression
ISO Diclofenac inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Diclofenac inhibits the reaction [TNF protein results in increased activity of RELA protein]
Diclofenac results in increased expression of RELA protein
Diclofenac affects the expression of RELA mRNA
diacerein inhibits the reaction [Diclofenac results in increased expression of RELA protein]; Diclofenac inhibits the reaction [Freund's Adjuvant results in increased phosphorylation of RELA protein]; Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; RELA mutant form inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]
CTD PMID:15489888 PMID:19393675 PMID:24752500 PMID:25935278 PMID:38582345 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Reln reelin decreases expression EXP Diclofenac results in decreased expression of RELN mRNA CTD PMID:26934552 NCBI chr 5:22,089,452...22,549,703
Ensembl chr 5:22,089,452...22,549,700
JBrowse link
G Ret ret proto-oncogene increases expression EXP Diclofenac results in increased expression of RET mRNA CTD PMID:26934552 NCBI chr 6:118,128,709...118,174,705
Ensembl chr 6:118,128,706...118,174,679
JBrowse link
G Rev3l REV3 like, DNA directed polymerase zeta catalytic subunit affects expression ISO Diclofenac affects the expression of REV3L mRNA CTD PMID:24752500 NCBI chr10:39,607,557...39,751,207
Ensembl chr10:39,608,114...39,751,207
JBrowse link
G Rgn regucalcin increases expression ISO Diclofenac results in increased expression of RGN mRNA CTD PMID:19022234 NCBI chr  X:20,413,980...20,428,328
Ensembl chr  X:20,416,026...20,428,328
JBrowse link
G Rgs16 regulator of G-protein signaling 16 decreases expression EXP Diclofenac results in decreased expression of RGS16 mRNA CTD PMID:35537566 NCBI chr 1:153,616,099...153,621,212
Ensembl chr 1:153,616,095...153,621,214
JBrowse link
G Rgs2 regulator of G-protein signaling 2 decreases expression EXP Diclofenac results in decreased expression of RGS2 mRNA CTD PMID:35537566 NCBI chr 1:143,875,076...143,879,887
Ensembl chr 1:143,875,076...143,879,899
JBrowse link
G Rgs4 regulator of G-protein signaling 4 decreases expression ISO Diclofenac results in decreased expression of RGS4 mRNA CTD PMID:19192274 NCBI chr 1:169,569,046...169,575,211
Ensembl chr 1:169,569,046...169,575,211
JBrowse link
G Rhob ras homolog family member B affects expression ISO Diclofenac affects the expression of RHOB mRNA CTD PMID:24752500 NCBI chr12:8,547,661...8,550,009
Ensembl chr12:8,547,661...8,550,009
JBrowse link
G Rhoj ras homolog family member J decreases expression EXP Diclofenac results in decreased expression of RHOJ mRNA CTD PMID:35537566 NCBI chr12:75,355,087...75,448,229
Ensembl chr12:75,355,096...75,448,230
JBrowse link
G Rhoq ras homolog family member Q affects expression ISO Diclofenac affects the expression of RHOQ mRNA CTD PMID:24752500 NCBI chr17:87,270,539...87,307,497
Ensembl chr17:87,270,510...87,307,497
JBrowse link
G Rhot2 ras homolog family member T2 affects expression ISO Diclofenac affects the expression of RHOT2 mRNA CTD PMID:24752500 NCBI chr17:26,057,431...26,063,499
Ensembl chr17:26,057,431...26,063,825
JBrowse link
G Ric8a RIC8 guanine nucleotide exchange factor A decreases expression EXP Diclofenac results in decreased expression of RIC8A mRNA CTD PMID:35537566 NCBI chr 7:140,437,310...140,443,644
Ensembl chr 7:140,436,870...140,444,285
JBrowse link
G Rigi RNA sensor RIG-I decreases expression ISO Diclofenac results in decreased expression of RIGI mRNA CTD PMID:19192274 NCBI chr 4:40,203,775...40,239,843
Ensembl chr 4:40,203,773...40,239,828
JBrowse link
G Rnase6 ribonuclease, RNase A family, 6 increases expression ISO Diclofenac results in increased expression of RNASE6 mRNA CTD PMID:30723492 NCBI chr14:51,361,365...51,369,644
Ensembl chr14:51,361,365...51,369,644
JBrowse link
G Rnasel ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) increases expression EXP Diclofenac results in increased expression of RNASEL mRNA CTD PMID:26934552 NCBI chr 1:153,625,089...153,644,441
Ensembl chr 1:153,625,172...153,639,967
JBrowse link
G Rnd1 Rho family GTPase 1 decreases expression EXP Diclofenac results in decreased expression of RND1 mRNA CTD PMID:35537566 NCBI chr15:98,567,086...98,575,342
Ensembl chr15:98,561,302...98,575,342
JBrowse link
G Rnf145 ring finger protein 145 increases expression EXP Diclofenac results in increased expression of RNF145 mRNA CTD PMID:35537566 NCBI chr11:44,409,486...44,456,347
Ensembl chr11:44,409,791...44,456,347
JBrowse link
G Rnf19b ring finger protein 19B decreases expression ISO Diclofenac results in decreased expression of RNF19B mRNA CTD PMID:19192274 NCBI chr 4:128,951,871...128,978,319
Ensembl chr 4:128,952,064...128,979,679
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 affects expression ISO Diclofenac affects the expression of ROCK1 mRNA CTD PMID:24752500 NCBI chr18:10,064,401...10,182,225
Ensembl chr18:10,064,401...10,182,045
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 affects expression ISO Diclofenac affects the expression of ROCK2 mRNA CTD PMID:24752500 NCBI chr12:16,944,808...17,038,275
Ensembl chr12:16,944,896...17,037,824
JBrowse link
G Ropn1 ropporin, rhophilin associated protein 1 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of ROPN1 mRNA CTD PMID:37844793 NCBI chr16:34,470,271...34,498,980
Ensembl chr16:34,470,291...34,498,988
JBrowse link
G Ropn1l ropporin 1-like increases expression EXP Diclofenac results in increased expression of ROPN1L mRNA CTD PMID:35537566 NCBI chr15:31,441,356...31,453,835
Ensembl chr15:31,441,357...31,453,883
JBrowse link
G Rora RAR-related orphan receptor alpha decreases expression EXP Diclofenac results in decreased expression of RORA mRNA CTD PMID:26934552 NCBI chr 9:68,560,627...69,295,528
Ensembl chr 9:68,561,068...69,295,528
JBrowse link
G Rorc RAR-related orphan receptor gamma increases expression EXP Diclofenac results in increased expression of RORC mRNA CTD PMID:22285467 NCBI chr 3:94,280,106...94,305,583
Ensembl chr 3:94,280,101...94,305,583
JBrowse link
G Rpa1 replication protein A1 affects expression ISO Diclofenac affects the expression of RPA1 mRNA CTD PMID:24752500 NCBI chr11:75,191,085...75,239,478
Ensembl chr11:75,188,992...75,239,150
JBrowse link
G Rpa2 replication protein A2 affects expression ISO Diclofenac affects the expression of RPA2 mRNA CTD PMID:24752500 NCBI chr 4:132,495,671...132,506,057
Ensembl chr 4:132,495,643...132,506,063
JBrowse link
G Rpap3 RNA polymerase II associated protein 3 increases expression EXP Diclofenac results in increased expression of RPAP3 mRNA CTD PMID:26934552 NCBI chr15:97,572,978...97,603,746
Ensembl chr15:97,572,978...97,603,706
JBrowse link
G Rpl39l ribosomal protein L39-like increases expression EXP Diclofenac results in increased expression of RPL39L mRNA CTD PMID:26934552 NCBI chr16:9,988,061...9,992,775
Ensembl chr16:9,988,090...9,992,775
JBrowse link
G Rps6ka1 ribosomal protein S6 kinase polypeptide 1 affects expression ISO Diclofenac affects the expression of RPS6KA1 mRNA CTD PMID:24752500 NCBI chr 4:133,574,601...133,615,466
Ensembl chr 4:133,574,601...133,615,108
JBrowse link
G Rps6ka5 ribosomal protein S6 kinase, polypeptide 5 decreases expression EXP Diclofenac results in decreased expression of RPS6KA5 mRNA CTD PMID:26934552 NCBI chr12:100,514,692...100,691,693
Ensembl chr12:100,514,698...100,693,242
JBrowse link
G Rps6kl1 ribosomal protein S6 kinase-like 1 increases expression ISO Diclofenac results in increased expression of RPS6KL1 mRNA CTD PMID:30723492 NCBI chr12:85,182,023...85,198,052
Ensembl chr12:85,182,023...85,198,038
JBrowse link
G Rras2 related RAS viral (r-ras) oncogene 2 affects expression ISO Diclofenac affects the expression of RRAS2 mRNA CTD PMID:24752500 NCBI chr 7:113,646,017...113,717,016
Ensembl chr 7:113,646,017...113,717,016
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 decreases expression ISO Diclofenac results in decreased expression of RSAD2 mRNA CTD PMID:19192274 NCBI chr12:26,492,742...26,506,451
Ensembl chr12:26,492,745...26,506,451
JBrowse link
G Runx2 runt related transcription factor 2 increases expression ISO Diclofenac results in increased expression of RUNX2 mRNA CTD PMID:30723492 NCBI chr17:44,806,873...45,125,518
Ensembl chr17:44,806,874...45,125,684
JBrowse link
G S100a8 S100 calcium binding protein A8 (calgranulin A) increases expression EXP
ISO
Diclofenac results in increased expression of S100A8 mRNA CTD PMID:24747151 PMID:26934552 PMID:28138970 NCBI chr 3:90,576,378...90,577,341
Ensembl chr 3:90,576,285...90,577,342
JBrowse link
G S100a9 S100 calcium binding protein A9 (calgranulin B) increases expression EXP
ISO
Diclofenac results in increased expression of S100A9 mRNA CTD PMID:24747151 PMID:26934552 PMID:27671914 PMID:28138970 NCBI chr 3:90,599,937...90,603,028
Ensembl chr 3:90,599,939...90,603,028
JBrowse link
G Saa1 serum amyloid A 1 increases expression EXP Diclofenac results in increased expression of SAA1 mRNA CTD PMID:26934552 NCBI chr 7:46,389,921...46,392,404
Ensembl chr 7:46,389,921...46,392,404
JBrowse link
G Saa2 serum amyloid A 2 increases expression EXP Diclofenac results in increased expression of SAA2 mRNA CTD PMID:26934552 NCBI chr 7:46,401,257...46,403,737
Ensembl chr 7:46,401,214...46,403,737
JBrowse link
G Saa3 serum amyloid A 3 increases expression EXP Diclofenac results in increased expression of SAA3 mRNA CTD PMID:26934552 NCBI chr 7:46,361,422...46,365,100
Ensembl chr 7:46,361,422...46,365,124
JBrowse link
G Saa4 serum amyloid A 4 decreases expression
increases expression
EXP Diclofenac results in decreased expression of SAA4 mRNA
Diclofenac results in increased expression of SAA4 mRNA
CTD PMID:26934552 NCBI chr 7:46,377,416...46,382,027
Ensembl chr 7:46,377,422...46,382,027
JBrowse link
G Sarm1 sterile alpha and HEAT/Armadillo motif containing 1 increases expression EXP Diclofenac results in increased expression of SARM1 mRNA CTD PMID:26934552 NCBI chr11:78,361,099...78,388,642
Ensembl chr11:78,363,156...78,388,580
JBrowse link
G Sars1 seryl-tRNA synthetase 1 affects expression ISO Diclofenac affects the expression of SARS1 mRNA CTD PMID:24752500 NCBI chr 3:108,332,180...108,352,575
Ensembl chr 3:108,332,181...108,352,525
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 affects expression ISO Diclofenac affects the expression of SAT1 mRNA CTD PMID:24752500 NCBI chr  X:153,996,128...153,999,345
Ensembl chr  X:153,996,128...153,999,445
JBrowse link
G Sat2 spermidine/spermine N1-acetyl transferase 2 affects expression ISO Diclofenac affects the expression of SAT2 mRNA CTD PMID:24752500 NCBI chr11:69,512,824...69,514,857
Ensembl chr11:69,512,850...69,514,696
JBrowse link
G Scara5 scavenger receptor class A, member 5 increases expression EXP Diclofenac results in increased expression of SCARA5 mRNA CTD PMID:26934552 NCBI chr14:65,903,852...66,002,275
Ensembl chr14:65,903,852...66,002,275
JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 increases expression EXP Diclofenac results in increased expression of SCD1 mRNA CTD PMID:26934552 NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318
JBrowse link
G Scn5a sodium channel, voltage-gated, type V, alpha decreases activity ISO Diclofenac results in decreased activity of SCN5A protein CTD PMID:33617802 NCBI chr 9:119,312,470...119,408,096
Ensembl chr 9:119,312,474...119,408,082
JBrowse link
G Sele selectin, endothelial cell increases expression EXP Diclofenac results in increased expression of SELE mRNA CTD PMID:26934552 NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246
JBrowse link
G Selenof selenoprotein F multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of SELENOF mRNA CTD PMID:37844793 NCBI chr 3:144,276,188...144,303,438
Ensembl chr 3:144,276,065...144,303,441
JBrowse link
G Sell selectin, lymphocyte decreases expression
increases expression
ISO
EXP
Diclofenac results in decreased expression of SELL protein
Diclofenac results in increased expression of SELL mRNA
CTD PMID:12147693 PMID:26934552 NCBI chr 1:163,889,556...163,908,354
Ensembl chr 1:163,889,551...163,911,750
JBrowse link
G Selp selectin, platelet decreases expression
multiple interactions
ISO Diclofenac results in decreased expression of SELP protein
Enalapril inhibits the reaction [Diclofenac results in decreased expression of SELP protein]
CTD PMID:14716214 NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595
JBrowse link
G Sema4b sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B increases expression EXP Diclofenac results in increased expression of SEMA4B mRNA CTD PMID:26934552 NCBI chr 7:79,836,618...79,876,394
Ensembl chr 7:79,836,589...79,876,275
JBrowse link
G Serpina10 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 increases expression
decreases expression
EXP Diclofenac results in increased expression of SERPINA10 mRNA
Diclofenac results in decreased expression of SERPINA10 mRNA
CTD PMID:26934552 NCBI chr12:103,582,934...103,597,681
Ensembl chr12:103,581,045...103,597,703
JBrowse link
G Serpina12 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 increases expression ISO Diclofenac results in increased expression of SERPINA12 mRNA CTD PMID:30723492 NCBI chr12:103,995,028...104,010,702
Ensembl chr12:103,995,028...104,010,702
JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N multiple interactions
increases expression
ISO
EXP
[Diclofenac co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SERPINA3N protein
Diclofenac results in increased expression of SERPINA3N mRNA
CTD PMID:25772430 PMID:26934552 NCBI chr12:104,372,967...104,380,588
Ensembl chr12:104,372,988...104,380,588
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 multiple interactions
increases expression
affects expression
ISO
EXP
Diclofenac promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of SERPINE1 mRNA]
Diclofenac results in increased expression of SERPINE1 mRNA
Diclofenac affects the expression of SERPINE1 mRNA
CTD PMID:23939143 PMID:24752500 PMID:26934552 PMID:35537566 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
JBrowse link
G Serpine2 serine (or cysteine) peptidase inhibitor, clade E, member 2 decreases expression EXP Diclofenac results in decreased expression of SERPINE2 mRNA CTD PMID:26934552 NCBI chr 1:79,772,038...79,836,382
Ensembl chr 1:79,771,914...79,838,897
JBrowse link
G Serpinf2 serine (or cysteine) peptidase inhibitor, clade F, member 2 increases expression EXP Diclofenac results in increased expression of SERPINF2 mRNA CTD PMID:26934552 NCBI chr11:75,322,562...75,330,327
Ensembl chr11:75,322,558...75,330,417
JBrowse link
G Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 decreases expression EXP Diclofenac results in decreased expression of SERPINH1 mRNA CTD PMID:26934552 NCBI chr 7:98,994,583...99,002,321
Ensembl chr 7:98,994,583...99,002,446
JBrowse link
G Sfn stratifin increases expression ISO Diclofenac results in increased expression of SFN mRNA CTD PMID:17379860 NCBI chr 4:133,327,867...133,329,163
Ensembl chr 4:133,327,867...133,329,479
JBrowse link
G Sfpq splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) increases expression EXP Diclofenac results in increased expression of SFPQ mRNA CTD PMID:26934552 NCBI chr 4:126,914,504...126,944,894
Ensembl chr 4:126,915,117...126,930,806
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression
decreases expression
ISO
EXP
Diclofenac results in increased expression of SGK1 mRNA
Diclofenac results in decreased expression of SGK1 mRNA
CTD PMID:30723492 PMID:35537566 NCBI chr10:21,758,083...21,875,802
Ensembl chr10:21,758,083...21,875,802
JBrowse link
G Sgk2 serum/glucocorticoid regulated kinase 2 decreases expression EXP Diclofenac results in decreased expression of SGK2 mRNA CTD PMID:26934552 NCBI chr 2:162,829,249...162,856,059
Ensembl chr 2:162,829,250...162,856,047
JBrowse link
G Sh3glb1 SH3-domain GRB2-like B1 (endophilin) affects expression ISO Diclofenac affects the expression of SH3GLB1 mRNA CTD PMID:24752500 NCBI chr 3:144,389,426...144,426,186
Ensembl chr 3:144,389,439...144,426,096
JBrowse link
G Shisa6 shisa family member 6 decreases expression EXP Diclofenac results in decreased expression of SHISA6 mRNA CTD PMID:26934552 NCBI chr11:66,102,551...66,418,715
Ensembl chr11:66,102,551...66,416,790
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 (soluble) affects expression ISO Diclofenac affects the expression of SHMT1 mRNA CTD PMID:24752500 NCBI chr11:60,679,723...60,702,062
Ensembl chr11:60,678,930...60,702,544
JBrowse link
G Shprh SNF2 histone linker PHD RING helicase decreases expression EXP Diclofenac results in decreased expression of SHPRH mRNA CTD PMID:26934552 NCBI chr10:11,024,765...11,093,339
Ensembl chr10:11,025,171...11,093,339
JBrowse link
G Sik1 salt inducible kinase 1 increases expression EXP Diclofenac results in increased expression of SIK1 mRNA CTD PMID:35537566 NCBI chr17:32,063,222...32,074,808
Ensembl chr17:32,063,224...32,074,778
JBrowse link
G Sin3a transcriptional regulator, SIN3A (yeast) affects expression ISO Diclofenac affects the expression of SIN3A mRNA CTD PMID:24752500 NCBI chr 9:56,979,271...57,035,652
Ensembl chr 9:56,979,324...57,035,650
JBrowse link
G Ska1 spindle and kinetochore associated complex subunit 1 increases expression ISO Diclofenac results in increased expression of SKA1 mRNA CTD PMID:30723492 NCBI chr18:74,328,370...74,340,889
Ensembl chr18:74,328,370...74,340,889
JBrowse link
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 decreases activity ISO Diclofenac results in decreased activity of SLC10A1 protein CTD PMID:39023798 NCBI chr12:80,999,959...81,015,479
Ensembl chr12:80,999,957...81,015,479
JBrowse link
G Slc10a2 solute carrier family 10, member 2 increases expression EXP Diclofenac results in increased expression of SLC10A2 mRNA CTD PMID:26934552 NCBI chr 8:5,133,219...5,155,287
Ensembl chr 8:5,133,219...5,155,351
JBrowse link
G Slc10a6 solute carrier family 10 (sodium/bile acid cotransporter family), member 6 increases expression EXP Diclofenac results in increased expression of SLC10A6 mRNA CTD PMID:26934552 NCBI chr 5:103,753,583...103,777,152
Ensembl chr 5:103,753,577...103,777,269
JBrowse link
G Slc13a3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 increases expression EXP Diclofenac results in increased expression of SLC13A3 mRNA CTD PMID:26934552 NCBI chr 2:165,247,215...165,315,117
Ensembl chr 2:165,246,948...165,315,150
JBrowse link
G Slc15a2 solute carrier family 15 (H+/peptide transporter), member 2 decreases expression EXP Diclofenac results in decreased expression of SLC15A2 mRNA CTD PMID:26934552 NCBI chr16:36,570,523...36,605,506
Ensembl chr16:36,570,539...36,605,324
JBrowse link
G Slc16a5 solute carrier family 16 (monocarboxylic acid transporters), member 5 increases expression EXP Diclofenac results in increased expression of SLC16A5 mRNA CTD PMID:26934552 NCBI chr11:115,353,231...115,365,224
Ensembl chr11:115,353,300...115,365,224
JBrowse link
G Slc17a6 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6 increases expression EXP Diclofenac results in increased expression of SLC17A6 mRNA CTD PMID:26934552 NCBI chr 7:51,271,578...51,320,874
Ensembl chr 7:51,271,754...51,320,867
JBrowse link
G Slc19a1 solute carrier family 19 (folate transporter), member 1 affects expression ISO Diclofenac affects the expression of SLC19A1 mRNA CTD PMID:24752500 NCBI chr10:76,868,103...76,886,266
Ensembl chr10:76,868,075...76,896,836
JBrowse link
G Slc19a2 solute carrier family 19 (thiamine transporter), member 2 increases expression EXP Diclofenac results in increased expression of SLC19A2 mRNA CTD PMID:35537566 NCBI chr 1:164,076,615...164,092,954
Ensembl chr 1:164,076,615...164,092,954
JBrowse link
G Slc1a4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 increases expression
decreases expression
EXP Diclofenac results in increased expression of SLC1A4 mRNA
Diclofenac results in decreased expression of SLC1A4 mRNA
CTD PMID:26934552 PMID:35537566 NCBI chr11:20,252,180...20,282,713
Ensembl chr11:20,252,180...20,282,713
JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 decreases activity ISO Diclofenac results in decreased activity of SLC22A1 protein CTD PMID:12388633 NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716
JBrowse link
G Slc22a19 solute carrier family 22 (organic anion transporter), member 19 decreases activity
multiple interactions
ISO Diclofenac results in decreased activity of SLC22A9 protein
Diclofenac inhibits the reaction [SLC22A19 protein affects the transport of estrone sulfate]
CTD PMID:12388633 PMID:16079298 NCBI chr19:7,650,440...7,688,675
Ensembl chr19:7,650,426...7,688,675
JBrowse link
G Slc22a21 solute carrier family 22 (organic cation transporter), member 21 increases expression EXP Diclofenac results in increased expression of SLC22A21 mRNA CTD PMID:26934552 NCBI chr11:53,840,780...53,871,159
Ensembl chr11:53,840,791...53,871,158
JBrowse link
G Slc22a27 solute carrier family 22, member 27 increases expression EXP Diclofenac results in increased expression of SLC22A27 mRNA CTD PMID:26934552 NCBI chr19:7,841,753...7,943,899
Ensembl chr19:7,841,753...7,943,392
JBrowse link
G Slc22a30 solute carrier family 22, member 30 decreases expression EXP Diclofenac results in decreased expression of SLC22A30 mRNA CTD PMID:26934552 NCBI chr19:8,312,735...8,382,475
Ensembl chr19:8,312,735...8,382,475
JBrowse link
G Slc22a6 solute carrier family 22 (organic anion transporter), member 6 decreases activity ISO Diclofenac results in decreased activity of SLC22A6 protein CTD PMID:12388633 NCBI chr19:8,595,360...8,605,663
Ensembl chr19:8,595,403...8,605,663
JBrowse link
G Slc22a7 solute carrier family 22 (organic anion transporter), member 7 decreases activity
multiple interactions
ISO Diclofenac results in decreased activity of SLC22A7 protein
Diclofenac inhibits the reaction [SLC22A7 protein results in increased transport of Tetracycline]
CTD PMID:12388633 PMID:15901346 NCBI chr17:46,743,111...46,749,403
Ensembl chr17:46,743,109...46,749,383
JBrowse link
G Slc22a8 solute carrier family 22 (organic anion transporter), member 8 multiple interactions ISO Diclofenac inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate] CTD PMID:11306713 NCBI chr19:8,568,576...8,589,199
Ensembl chr19:8,568,618...8,589,199
JBrowse link
G Slc23a1 solute carrier family 23 (nucleobase transporters), member 1 increases expression EXP Diclofenac results in increased expression of SLC23A1 mRNA CTD PMID:26934552 NCBI chr18:35,747,657...35,762,900
Ensembl chr18:35,747,657...35,760,297
JBrowse link
G Slc23a2 solute carrier family 23 (nucleobase transporters), member 2 multiple interactions ISO Diclofenac inhibits the reaction [SLC23A2 protein results in increased uptake of Ascorbic Acid] CTD PMID:17092984 NCBI chr 2:131,894,416...131,987,287
Ensembl chr 2:131,894,416...131,987,028
JBrowse link
G Slc25a22 solute carrier family 25 (mitochondrial carrier, glutamate), member 22 decreases expression EXP Diclofenac results in decreased expression of SLC25A22 mRNA CTD PMID:26934552 NCBI chr 7:141,009,662...141,017,787
Ensembl chr 7:141,009,657...141,017,805
JBrowse link
G Slc25a30 solute carrier family 25, member 30 decreases expression EXP Diclofenac results in decreased expression of SLC25A30 mRNA CTD PMID:26934552 NCBI chr14:75,994,986...76,024,477
Ensembl chr14:75,997,557...76,024,477
JBrowse link
G Slc25a33 solute carrier family 25, member 33 decreases expression EXP Diclofenac results in decreased expression of SLC25A33 mRNA CTD PMID:26934552 NCBI chr 4:149,828,493...149,858,746
Ensembl chr 4:149,828,493...149,858,734
JBrowse link
G Slc29a1 solute carrier family 29 (nucleoside transporters), member 1 decreases expression EXP Diclofenac results in decreased expression of SLC29A1 mRNA CTD PMID:26934552 NCBI chr17:45,896,126...45,910,544
Ensembl chr17:45,896,126...45,910,532
JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 decreases expression EXP Diclofenac results in decreased expression of SLC2A2 mRNA CTD PMID:26934552 NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508
JBrowse link
G Slc30a5 solute carrier family 30 (zinc transporter), member 5 increases expression EXP Diclofenac results in increased expression of SLC30A5 mRNA CTD PMID:26934552 NCBI chr13:100,939,153...100,969,988
Ensembl chr13:100,939,156...100,969,935
JBrowse link
G Slc36a4 solute carrier family 36 (proton/amino acid symporter), member 4 increases expression EXP Diclofenac results in increased expression of SLC36A4 mRNA CTD PMID:26934552 NCBI chr 9:15,621,034...15,653,684
Ensembl chr 9:15,621,034...15,654,657
JBrowse link
G Slc37a1 solute carrier family 37 (glycerol-3-phosphate transporter), member 1 increases expression EXP Diclofenac results in increased expression of SLC37A1 mRNA CTD PMID:26934552 NCBI chr17:31,495,722...31,569,683
Ensembl chr17:31,505,766...31,569,713
JBrowse link
G Slc38a7 solute carrier family 38, member 7 decreases expression EXP Diclofenac results in decreased expression of SLC38A7 mRNA CTD PMID:35537566 NCBI chr 8:96,562,548...96,580,205
Ensembl chr 8:96,562,548...96,580,167
JBrowse link
G Slc39a14 solute carrier family 39 (zinc transporter), member 14 increases expression EXP Diclofenac results in increased expression of SLC39A14 mRNA CTD PMID:26934552 NCBI chr14:70,540,916...70,588,873
Ensembl chr14:70,540,918...70,588,874
JBrowse link
G Slc3a1 solute carrier family 3, member 1 increases expression EXP Diclofenac results in increased expression of SLC3A1 mRNA CTD PMID:26934552 NCBI chr17:85,335,775...85,371,669
Ensembl chr17:85,335,804...85,371,664
JBrowse link
G Slc41a1 solute carrier family 41, member 1 increases expression EXP Diclofenac results in increased expression of SLC41A1 mRNA CTD PMID:26934552 NCBI chr 1:131,755,236...131,776,601
Ensembl chr 1:131,755,231...131,776,603
JBrowse link
G Slc41a2 solute carrier family 41, member 2 increases expression EXP Diclofenac results in increased expression of SLC41A2 mRNA CTD PMID:26934552 NCBI chr10:83,066,712...83,174,657
Ensembl chr10:83,066,712...83,173,746
JBrowse link
G Slc43a1 solute carrier family 43, member 1 increases expression EXP Diclofenac results in increased expression of SLC43A1 mRNA CTD PMID:26934552 NCBI chr 2:84,669,196...84,693,930
Ensembl chr 2:84,669,194...84,693,938
JBrowse link
G Slc45a4 solute carrier family 45, member 4 decreases expression EXP Diclofenac results in decreased expression of SLC45A4 mRNA CTD PMID:26934552 NCBI chr15:73,449,267...73,517,606
Ensembl chr15:73,449,273...73,517,611
JBrowse link
G Slc46a2 solute carrier family 46, member 2 decreases expression EXP Diclofenac results in decreased expression of SLC46A2 mRNA CTD PMID:26934552 NCBI chr 4:59,905,899...59,915,056
Ensembl chr 4:59,905,126...59,915,056
JBrowse link
G Slc46a3 solute carrier family 46, member 3 decreases expression EXP Diclofenac results in decreased expression of SLC46A3 mRNA CTD PMID:35537566 NCBI chr 5:147,812,707...147,831,670
Ensembl chr 5:147,815,247...147,831,625
JBrowse link
G Slc4a1 solute carrier family 4 (anion exchanger), member 1 increases expression EXP Diclofenac results in increased expression of SLC4A1 mRNA CTD PMID:26934552 NCBI chr11:102,239,646...102,256,107
Ensembl chr11:102,239,650...102,257,029
JBrowse link
G Slc4a4 solute carrier family 4 (anion exchanger), member 4 increases expression EXP Diclofenac results in increased expression of SLC4A4 mRNA CTD PMID:26934552 NCBI chr 5:88,941,717...89,387,515
Ensembl chr 5:89,034,345...89,387,512
JBrowse link
G Slc6a20a solute carrier family 6 (neurotransmitter transporter), member 20A increases expression EXP Diclofenac results in increased expression of SLC6A20A mRNA CTD PMID:26934552 NCBI chr 9:123,465,972...123,507,897
Ensembl chr 9:123,463,835...123,507,950
JBrowse link
G Slc6a9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 decreases expression EXP Diclofenac results in decreased expression of SLC6A9 mRNA CTD PMID:35537566 NCBI chr 4:117,692,240...117,726,502
Ensembl chr 4:117,691,703...117,732,395
JBrowse link
G Slc7a1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 decreases expression EXP Diclofenac results in decreased expression of SLC7A1 mRNA CTD PMID:35537566 NCBI chr 5:148,264,220...148,336,714
Ensembl chr 5:148,264,220...148,336,714
JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 decreases expression
increases expression
ISO
EXP
Diclofenac results in decreased expression of SLC7A11 mRNA
Diclofenac results in increased expression of SLC7A11 mRNA
CTD PMID:19192274 PMID:32816093 PMID:33785417 PMID:35537566 NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063
JBrowse link
G Slc7a3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 increases expression EXP Diclofenac results in increased expression of SLC7A3 mRNA CTD PMID:26934552 NCBI chr  X:100,122,752...100,134,058
Ensembl chr  X:100,122,816...100,129,626
JBrowse link
G Slc7a4 solute carrier family 7 (cationic amino acid transporter, y+ system), member 4 increases expression EXP Diclofenac results in increased expression of SLC7A4 mRNA CTD PMID:26934552 NCBI chr16:17,389,882...17,394,619
Ensembl chr16:17,389,882...17,401,078
JBrowse link
G Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 decreases expression EXP Diclofenac results in decreased expression of SLC7A5 mRNA CTD PMID:35537566 NCBI chr 8:122,607,885...122,634,425
Ensembl chr 8:122,607,889...122,634,433
JBrowse link
G Slc7a8 solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 increases expression ISO
EXP
Diclofenac results in increased expression of SLC7A8 mRNA CTD PMID:19192274 PMID:26934552 NCBI chr14:54,959,672...55,019,343
Ensembl chr14:54,959,666...55,019,403
JBrowse link
G Slco1a1 solute carrier organic anion transporter family, member 1a1 decreases expression
multiple interactions
EXP Diclofenac results in decreased expression of SLCO1A1 mRNA
[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in decreased expression of SLCO1A1 mRNA; [Sodium Selenite co-treated with Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in decreased expression of SLCO1A1 mRNA
CTD PMID:26934552 PMID:38945390 NCBI chr 6:141,853,007...141,892,688
Ensembl chr 6:141,853,008...141,892,688
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 decreases expression EXP Diclofenac results in decreased expression of SLCO1A4 mRNA CTD PMID:26934552 NCBI chr 6:141,751,164...141,802,011
Ensembl chr 6:141,751,166...141,801,925
JBrowse link
G Slco2a1 solute carrier organic anion transporter family, member 2a1 multiple interactions ISO Diclofenac inhibits the reaction [SLCO2A1 protein results in increased transport of Dinoprostone] CTD PMID:19843975 NCBI chr 9:102,885,686...102,973,201
Ensembl chr 9:102,865,911...102,973,201
JBrowse link
G Slirp SRA stem-loop interacting RNA binding protein multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of SLIRP mRNA CTD PMID:37844793 NCBI chr12:87,490,666...87,496,694
Ensembl chr12:87,490,666...87,498,976
JBrowse link
G Slitrk5 SLIT and NTRK-like family, member 5 increases expression ISO Diclofenac results in increased expression of SLITRK5 mRNA CTD PMID:30723492 NCBI chr14:111,912,547...111,920,576
Ensembl chr14:111,912,529...111,920,573
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Diclofenac results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 2:164,195,990...164,231,086
Ensembl chr 2:164,195,990...164,231,015
JBrowse link
G Smad1 SMAD family member 1 increases expression EXP Diclofenac results in increased expression of SMAD1 mRNA CTD PMID:26934552 NCBI chr 8:80,065,024...80,126,057
Ensembl chr 8:80,065,024...80,126,147
JBrowse link
G Smad4 SMAD family member 4 affects expression ISO Diclofenac affects the expression of SMAD4 mRNA CTD PMID:24752500 NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851
JBrowse link
G Smarca5 SNF2 related chromatin remodeling ATPase 5 increases expression EXP Diclofenac results in increased expression of SMARCA5 mRNA CTD PMID:26934552 NCBI chr 8:81,426,572...81,466,088
Ensembl chr 8:81,425,136...81,466,126
JBrowse link
G Smarcb1 SWI/SNF related BAF chromatin remodeling complex subunit B1 increases expression EXP Diclofenac results in increased expression of SMARCB1 mRNA CTD PMID:26934552 NCBI chr10:75,732,603...75,757,448
Ensembl chr10:75,732,603...75,757,451
JBrowse link
G Snca synuclein, alpha increases expression EXP Diclofenac results in increased expression of SNCA mRNA CTD PMID:26934552 NCBI chr 6:60,708,557...60,806,839
Ensembl chr 6:60,708,559...60,806,839
JBrowse link
G Snord14e small nucleolar RNA, C/D box 14E increases expression EXP Diclofenac results in increased expression of SNORD14E mRNA CTD PMID:35537566 NCBI chr 9:40,716,044...40,716,134
Ensembl chr 9:40,716,044...40,716,133
JBrowse link
G Snx10 sorting nexin 10 increases expression EXP Diclofenac results in increased expression of SNX10 mRNA CTD PMID:26934552 NCBI chr 6:51,500,882...51,567,659
Ensembl chr 6:51,500,881...51,567,659
JBrowse link
G Soat2 sterol O-acyltransferase 2 decreases expression EXP Diclofenac results in decreased expression of SOAT2 mRNA CTD PMID:35537566 NCBI chr15:102,058,853...102,071,871
Ensembl chr15:102,058,961...102,071,904
JBrowse link
G Socs3 suppressor of cytokine signaling 3 increases expression EXP Diclofenac results in increased expression of SOCS3 mRNA CTD PMID:26934552 PMID:35537566 NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873
JBrowse link
G Socs6 suppressor of cytokine signaling 6 affects expression ISO Diclofenac affects the expression of SOCS6 mRNA CTD PMID:24752500 NCBI chr18:88,883,293...88,912,623
Ensembl chr18:88,683,348...88,945,605
JBrowse link
G Socs7 suppressor of cytokine signaling 7 affects expression ISO Diclofenac affects the expression of SOCS7 mRNA CTD PMID:24752500 NCBI chr11:97,253,044...97,289,368
Ensembl chr11:97,253,261...97,289,368
JBrowse link
G Sod1 superoxide dismutase 1, soluble increases secretion
multiple interactions
decreases activity
increases expression
EXP
ISO
Diclofenac results in increased secretion of SOD1 protein
[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in decreased expression of SOD1 mRNA; Sodium Selenite promotes the reaction [[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in decreased expression of SOD1 mRNA]
Diclofenac results in decreased activity of SOD1 protein
Acetylcysteine inhibits the reaction [Diclofenac results in decreased activity of SOD1 protein]; Silymarin inhibits the reaction [Diclofenac results in decreased activity of SOD1 protein]
Diclofenac results in increased expression of SOD1 mRNA
CTD PMID:24038040 PMID:28535741 PMID:29027214 PMID:38945390 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial increases expression
multiple interactions
affects expression
ISO Diclofenac results in increased expression of SOD2 mRNA; Diclofenac results in increased expression of SOD2 protein
[Diclofenac co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SOD2 protein; Diclofenac inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of SOD2 mRNA]; rebamipide promotes the reaction [Diclofenac results in increased expression of SOD2 protein]
Diclofenac affects the expression of SOD2 mRNA
CTD PMID:19022234 PMID:22653900 PMID:23939143 PMID:24752500 PMID:25772430 More... NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Sord sorbitol dehydrogenase multiple interactions
increases secretion
EXP Acetylcysteine inhibits the reaction [Diclofenac results in increased secretion of SORD protein]; Buthionine Sulfoximine promotes the reaction [Diclofenac results in increased secretion of SORD protein] CTD PMID:12763371 NCBI chr 2:122,065,320...122,095,818
Ensembl chr 2:122,065,230...122,095,821
JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 affects expression ISO Diclofenac affects the expression of SOS1 mRNA CTD PMID:24752500 NCBI chr17:80,701,181...80,787,882
Ensembl chr17:80,701,180...80,787,882
JBrowse link
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 affects expression ISO Diclofenac affects the expression of SOS2 mRNA CTD PMID:24752500 NCBI chr12:69,630,535...69,728,626
Ensembl chr12:69,630,536...69,728,626
JBrowse link
G Sox8 SRY (sex determining region Y)-box 8 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of SOX8 mRNA CTD PMID:37844793 NCBI chr17:25,784,865...25,789,666
Ensembl chr17:25,784,634...25,789,726
JBrowse link
G Spaca6 sperm acrosome associated 6 increases expression ISO Diclofenac results in increased expression of SPACA6 mRNA CTD PMID:30723492 NCBI chr17:18,045,955...18,063,274
Ensembl chr17:18,047,420...18,063,271
JBrowse link
G Spata17 spermatogenesis associated 17 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of SPATA17 mRNA CTD PMID:37844793 NCBI chr 1:186,741,811...186,947,705
Ensembl chr 1:186,776,845...186,947,662
JBrowse link
G Spata19 spermatogenesis associated 19 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of SPATA19 mRNA CTD PMID:37844793 NCBI chr 9:27,308,103...27,313,007
Ensembl chr 9:27,308,096...27,313,081
JBrowse link
G Spata25 spermatogenesis associated 25 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of SPATA25 mRNA CTD PMID:37844793 NCBI chr 2:164,669,302...164,670,454
Ensembl chr 2:164,668,309...164,670,457
JBrowse link
G Spdl1 spindle apparatus coiled-coil protein 1 decreases expression EXP Diclofenac results in decreased expression of SPDL1 mRNA CTD PMID:35537566 NCBI chr11:34,700,012...34,724,492
Ensembl chr11:34,700,017...34,724,468
JBrowse link
G Spem1 spermatid maturation 1 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of SPEM1 mRNA CTD PMID:37844793 NCBI chr11:69,711,697...69,712,991
Ensembl chr11:69,711,702...69,713,006
JBrowse link
G Spink2 serine peptidase inhibitor, Kazal type 2 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of SPINK2 mRNA CTD PMID:37844793 NCBI chr 5:77,352,953...77,364,106
Ensembl chr 5:77,352,954...77,359,318
JBrowse link
G Spmip10 sperm microtubule inner protein 10 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of TEX43 mRNA CTD PMID:37844793 NCBI chr18:56,720,690...56,727,855
Ensembl chr18:56,721,422...56,727,854
JBrowse link
G Spry3 sprouty RTK signaling antagonist 3 increases expression ISO Diclofenac results in increased expression of SPRY3 mRNA CTD PMID:30723492
G Spry4 sprouty RTK signaling antagonist 4 decreases expression EXP Diclofenac results in decreased expression of SPRY4 mRNA CTD PMID:26934552 NCBI chr18:38,719,300...38,734,400
Ensembl chr18:38,719,300...38,734,468
JBrowse link
G Sqle squalene epoxidase increases expression EXP Diclofenac results in increased expression of SQLE mRNA CTD PMID:26934552 NCBI chr15:59,186,941...59,203,042
Ensembl chr15:59,186,926...59,203,041
JBrowse link
G Src Rous sarcoma oncogene affects expression ISO Diclofenac affects the expression of SRC mRNA CTD PMID:24752500 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases expression EXP Diclofenac results in decreased expression of SRD5A1 mRNA CTD PMID:26934552 NCBI chr13:69,721,568...69,759,611
Ensembl chr13:69,721,568...69,759,561
JBrowse link
G Srebf2 sterol regulatory element binding factor 2 increases expression
multiple interactions
EXP Diclofenac results in increased expression of SREBF2 mRNA
[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in increased expression of SREBF2 mRNA; Sodium Selenite inhibits the reaction [[Cadmium co-treated with Arsenic co-treated with Mercury co-treated with Diclofenac co-treated with flumequine] results in increased expression of SREBF2 mRNA]
CTD PMID:26934552 PMID:38945390 NCBI chr15:82,031,455...82,089,580
Ensembl chr15:82,031,382...82,089,580
JBrowse link
G Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) increases expression
multiple interactions
ISO
EXP
Diclofenac results in increased expression of SRXN1 mRNA
Diclofenac results in increased expression of SRXN1 protein
NFE2L2 protein affects the reaction [Diclofenac results in increased expression of SRXN1 mRNA]
CTD PMID:24752500 PMID:27358234 NCBI chr 2:151,946,738...151,953,296
Ensembl chr 2:151,947,436...151,953,296
JBrowse link
G St6gal1 beta galactoside alpha 2,6 sialyltransferase 1 increases expression EXP Diclofenac results in increased expression of ST6GAL1 mRNA CTD PMID:26934552 NCBI chr16:23,043,478...23,179,100
Ensembl chr16:23,043,490...23,179,100
JBrowse link
G Stat1 signal transducer and activator of transcription 1 decreases expression
multiple interactions
affects expression
EXP
ISO
Diclofenac results in decreased expression of STAT1 mRNA
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[Diclofenac co-treated with IFNG protein] results in increased phosphorylation of STAT1 protein]; 2-aminoethoxydiphenyl borate inhibits the reaction [[Diclofenac co-treated with IFNG protein] results in increased phosphorylation of STAT1 protein]; [Diclofenac co-treated with IFNG protein] results in increased phosphorylation of STAT1 protein; Calcium promotes the reaction [[Diclofenac co-treated with IFNG protein] results in increased phosphorylation of STAT1 protein]; pyrazolanthrone inhibits the reaction [[Diclofenac co-treated with IFNG protein] results in increased phosphorylation of STAT1 protein]
Diclofenac affects the expression of STAT1 mRNA
CTD PMID:19192274 PMID:22285467 PMID:24752500 PMID:26609140 NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression
affects expression
EXP
ISO
Diclofenac results in increased expression of STAT3 mRNA
Diclofenac affects the expression of STAT3 mRNA
CTD PMID:22285467 PMID:23506792 PMID:24752500 PMID:26934552 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
JBrowse link
G Stat4 signal transducer and activator of transcription 4 decreases expression ISO Diclofenac results in decreased expression of STAT4 mRNA CTD PMID:19192274 NCBI chr 1:52,026,265...52,146,348
Ensembl chr 1:52,026,307...52,146,348
JBrowse link
G Stat5b signal transducer and activator of transcription 5B affects expression ISO Diclofenac affects the expression of STAT5B mRNA CTD PMID:24752500 NCBI chr11:100,671,557...100,741,407
Ensembl chr11:100,671,557...100,741,550
JBrowse link
G Stat6 signal transducer and activator of transcription 6 affects expression ISO Diclofenac affects the expression of STAT6 mRNA CTD PMID:24752500 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826
JBrowse link
G Steap4 STEAP family member 4 increases expression
decreases expression
EXP Diclofenac results in increased expression of STEAP4 mRNA
Diclofenac results in decreased expression of STEAP4 mRNA
CTD PMID:26934552 NCBI chr 5:8,010,472...8,032,213
Ensembl chr 5:8,010,457...8,032,213
JBrowse link
G Stil Scl/Tal1 interrupting locus increases expression ISO Diclofenac results in increased expression of STIL mRNA CTD PMID:30723492 NCBI chr 4:114,857,287...114,900,404
Ensembl chr 4:114,857,356...114,900,393
JBrowse link
G Stk31 serine threonine kinase 31 decreases expression EXP Diclofenac results in decreased expression of STK31 mRNA CTD PMID:26934552 NCBI chr 6:49,372,441...49,446,440
Ensembl chr 6:49,372,538...49,446,435
JBrowse link
G Stmn1 stathmin 1 affects expression ISO Diclofenac affects the expression of STMN1 mRNA CTD PMID:24752500 NCBI chr 4:134,195,631...134,201,154
Ensembl chr 4:134,195,631...134,201,154
JBrowse link
G Sts steroid sulfatase increases expression ISO Diclofenac results in increased expression of STS mRNA CTD PMID:19192274 NCBI chr  X:168,856,332...169,015,037
Ensembl chr  X:168,909,030...169,014,924
JBrowse link
G Sucnr1 succinate receptor 1 decreases expression EXP Diclofenac results in decreased expression of SUCNR1 mRNA CTD PMID:26934552 NCBI chr 3:59,989,290...59,994,987
Ensembl chr 3:59,989,290...59,994,987
JBrowse link
G Sult1e1 sulfotransferase family 1E, member 1 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of SULT1E1 mRNA CTD PMID:37844793 NCBI chr 5:87,723,827...87,739,470
Ensembl chr 5:87,723,828...87,739,453
JBrowse link
G Suv39h1 suppressor of variegation 3-9 1 affects expression ISO Diclofenac affects the expression of SUV39H1 mRNA CTD PMID:24752500 NCBI chr  X:7,927,401...7,940,994
Ensembl chr  X:7,927,410...7,940,999
JBrowse link
G Syce3 synaptonemal complex central element protein 3 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of SYCE3 mRNA CTD PMID:37844793 NCBI chr15:89,274,377...89,294,706
Ensembl chr15:89,274,377...89,294,706
JBrowse link
G Sycp3 synaptonemal complex protein 3 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of SYCP3 mRNA CTD PMID:37844793 NCBI chr10:88,295,449...88,309,098
Ensembl chr10:88,295,431...88,309,098
JBrowse link
G Syne1 spectrin repeat containing, nuclear envelope 1 decreases expression EXP Diclofenac results in decreased expression of SYNE1 mRNA CTD PMID:35537566 NCBI chr10:4,970,192...5,501,013
Ensembl chr10:4,970,917...5,501,482
JBrowse link
G Syne4 spectrin repeat containing, nuclear envelope family member 4 increases expression ISO Diclofenac results in increased expression of SYNE4 mRNA CTD PMID:30723492 NCBI chr 7:30,014,268...30,018,471
Ensembl chr 7:30,014,232...30,018,471
JBrowse link
G Tac1 tachykinin 1 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of TAC1 mRNA CTD PMID:37844793 NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834
JBrowse link
G Taf3 TATA-box binding protein associated factor 3 affects expression ISO Diclofenac affects the expression of TAF3 mRNA CTD PMID:24752500 NCBI chr 2:9,919,363...10,053,420
Ensembl chr 2:9,919,363...10,053,407
JBrowse link
G Taf9b TATA-box binding protein associated factor 9B affects expression ISO Diclofenac affects the expression of TAF9B mRNA CTD PMID:24752500 NCBI chr  X:105,250,480...105,264,764
Ensembl chr  X:105,250,489...105,264,764
JBrowse link
G Tank TRAF family member-associated Nf-kappa B activator affects expression ISO Diclofenac affects the expression of TANK mRNA CTD PMID:24752500 NCBI chr 2:61,408,901...61,484,515
Ensembl chr 2:61,408,929...61,484,515
JBrowse link
G Tarbp2 TARBP2, RISC loading complex RNA binding subunit multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of TARBP2 mRNA CTD PMID:37844793 NCBI chr15:102,423,327...102,432,112
Ensembl chr15:102,426,627...102,432,111
JBrowse link
G Tardbp TAR DNA binding protein decreases expression EXP Diclofenac results in decreased expression of TARDBP mRNA CTD PMID:26934552 NCBI chr 4:148,696,839...148,711,672
Ensembl chr 4:148,696,839...148,711,476
JBrowse link
G Tas1r3 taste receptor, type 1, member 3 increases expression ISO Diclofenac results in increased expression of TAS1R3 mRNA CTD PMID:30723492 NCBI chr 4:155,943,725...155,947,810
Ensembl chr 4:155,943,725...155,947,819
JBrowse link
G Tasor transcription activation suppressor affects expression ISO Diclofenac affects the expression of TASOR mRNA CTD PMID:24752500 NCBI chr14:27,150,759...27,205,512
Ensembl chr14:27,150,791...27,205,512
JBrowse link
G Tbc1d21 TBC1 domain family, member 21 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of TBC1D21 mRNA CTD PMID:37844793 NCBI chr 9:58,266,999...58,277,762
Ensembl chr 9:58,266,987...58,277,738
JBrowse link
G Tbc1d31 TBC1 domain family, member 31 decreases expression EXP Diclofenac results in decreased expression of TBC1D31 mRNA CTD PMID:35537566 NCBI chr15:57,775,081...57,833,464
Ensembl chr15:57,775,595...57,833,463
JBrowse link
G Tbx21 T-box 21 decreases expression EXP Diclofenac results in decreased expression of TBX21 mRNA CTD PMID:22285467 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157
JBrowse link
G Tbx3 T-box 3 increases expression EXP Diclofenac results in increased expression of TBX3 mRNA CTD PMID:26934552 NCBI chr 5:119,808,600...119,822,789
Ensembl chr 5:119,808,734...119,822,789
JBrowse link
G Tcf3 transcription factor 3 affects expression ISO Diclofenac affects the expression of TCF3 mRNA CTD PMID:24752500 NCBI chr10:80,245,375...80,269,814
Ensembl chr10:80,245,348...80,269,481
JBrowse link
G Tcf7l2 transcription factor 7 like 2, T cell specific, HMG box affects expression ISO Diclofenac affects the expression of TCF7L2 mRNA CTD PMID:24752500 NCBI chr19:55,730,227...55,922,091
Ensembl chr19:55,730,252...55,922,086
JBrowse link
G Tcl1b3 T cell leukemia/lymphoma 1B, 3 increases expression EXP Diclofenac results in increased expression of TCL1B3 mRNA CTD PMID:26934552 NCBI chr12:105,157,304...105,161,658
Ensembl chr12:105,157,302...105,161,871
JBrowse link
G Tdrd7 tudor domain containing 7 affects expression ISO Diclofenac affects the expression of TDRD7 mRNA CTD PMID:24752500 NCBI chr 4:45,965,335...46,034,766
Ensembl chr 4:45,965,334...46,034,761
JBrowse link
G Tecpr1 tectonin beta-propeller repeat containing 1 decreases expression EXP Diclofenac results in decreased expression of TECPR1 mRNA CTD PMID:35537566 NCBI chr 5:144,131,260...144,160,433
Ensembl chr 5:144,131,260...144,160,433
JBrowse link
G Tekt4 tektin 4 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of TEKT4 mRNA CTD PMID:37844793 NCBI chr17:25,673,511...25,695,576
Ensembl chr17:25,673,515...25,695,576
JBrowse link
G Tex12 testis expressed 12 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of TEX12 mRNA CTD PMID:37844793 NCBI chr 9:50,468,448...50,472,568
Ensembl chr 9:50,468,119...50,472,625
JBrowse link
G Tfdp1 transcription factor Dp 1 affects expression ISO Diclofenac affects the expression of TFDP1 mRNA CTD PMID:24752500 NCBI chr 8:13,388,273...13,428,448
Ensembl chr 8:13,388,751...13,428,448
JBrowse link
G Tff3 trefoil factor 3, intestinal increases expression EXP Diclofenac results in increased expression of TFF3 mRNA CTD PMID:26934552 NCBI chr17:31,344,280...31,348,585
Ensembl chr17:31,344,280...31,348,620
JBrowse link
G Tfrc transferrin receptor increases expression EXP Diclofenac results in increased expression of TFRC mRNA CTD PMID:26934552 NCBI chr16:32,427,714...32,451,612
Ensembl chr16:32,427,738...32,451,612
JBrowse link
G Tgfa transforming growth factor alpha increases expression ISO Diclofenac results in increased expression of TGFA mRNA CTD PMID:19022234 NCBI chr 6:86,172,020...86,252,726
Ensembl chr 6:86,172,205...86,252,701
JBrowse link
G Tgfb2 transforming growth factor, beta 2 decreases expression ISO Diclofenac results in decreased expression of TGFB2 mRNA CTD PMID:17379860 NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186
JBrowse link
G Tgm1 transglutaminase 1, K polypeptide increases expression EXP Diclofenac results in increased expression of TGM1 mRNA CTD PMID:26934552 NCBI chr14:55,937,466...55,951,378
Ensembl chr14:55,937,466...55,951,383
JBrowse link
G Tifa TRAF-interacting protein with forkhead-associated domain increases expression EXP Diclofenac results in increased expression of TIFA mRNA CTD PMID:26934552 NCBI chr 3:127,582,524...127,592,043
Ensembl chr 3:127,583,454...127,625,813
JBrowse link
G Timm8a2 translocase of inner mitochondrial membrane 8A2 increases expression EXP Diclofenac results in increased expression of TIMM8A2 mRNA CTD PMID:26934552 NCBI chr14:122,265,089...122,275,834
Ensembl chr14:122,272,086...122,275,832
JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 decreases expression
increases expression
ISO
EXP
Diclofenac results in decreased expression of TIMP1 mRNA
Diclofenac results in increased expression of TIMP1 mRNA
CTD PMID:19022234 PMID:26934552 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974
JBrowse link
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein increases expression EXP Diclofenac results in increased expression of TIRAP mRNA CTD PMID:26934552 NCBI chr 9:35,095,687...35,111,587
Ensembl chr 9:35,095,847...35,111,587
JBrowse link
G Tjp1 tight junction protein 1 affects expression ISO Diclofenac affects the expression of TJP1 mRNA CTD PMID:24752500 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529
JBrowse link
G Tk1 thymidine kinase 1 affects expression ISO Diclofenac affects the expression of TK1 mRNA CTD PMID:24752500 NCBI chr11:117,706,345...117,716,913
Ensembl chr11:117,706,352...117,716,918
JBrowse link
G Tk2 thymidine kinase 2, mitochondrial affects expression ISO Diclofenac affects the expression of TK2 mRNA CTD PMID:24752500 NCBI chr 8:104,953,323...104,975,224
Ensembl chr 8:104,953,317...104,975,190
JBrowse link
G Tlcd1 TLC domain containing 1 increases expression EXP Diclofenac results in increased expression of TLCD1 mRNA CTD PMID:35537566 NCBI chr11:78,068,956...78,071,646
Ensembl chr11:78,067,537...78,072,735
JBrowse link
G Tlk1 tousled-like kinase 1 decreases expression EXP Diclofenac results in decreased expression of TLK1 mRNA CTD PMID:26934552 NCBI chr 2:70,542,751...70,656,505
Ensembl chr 2:70,542,751...70,656,072
JBrowse link
G Tlr13 toll-like receptor 13 increases expression EXP Diclofenac results in increased expression of TLR13 mRNA CTD PMID:26934552 NCBI chr  X:105,186,881...105,204,099
Ensembl chr  X:105,186,810...105,204,099
JBrowse link
G Tlr2 toll-like receptor 2 decreases expression
increases expression
ISO
EXP
Diclofenac results in decreased expression of TLR2 mRNA
Diclofenac results in increased expression of TLR2 mRNA
CTD PMID:19192274 PMID:26934552 PMID:29027214 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions
increases expression
ISO diacerein inhibits the reaction [Diclofenac results in increased expression of TLR4 protein] CTD PMID:38582345 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 increases expression EXP Diclofenac results in increased expression of TM7SF2 mRNA CTD PMID:35537566 NCBI chr19:6,112,851...6,117,880
Ensembl chr19:6,112,851...6,118,403
JBrowse link
G Tmem176a transmembrane protein 176A increases expression
decreases expression
EXP Diclofenac results in increased expression of TMEM176A mRNA
Diclofenac results in decreased expression of TMEM176A mRNA
CTD PMID:26934552 NCBI chr 6:48,818,417...48,822,298
Ensembl chr 6:48,817,853...48,824,005
JBrowse link
G Tnc tenascin C decreases expression EXP Diclofenac results in decreased expression of TNC mRNA CTD PMID:35537566 NCBI chr 4:63,878,022...63,965,554
Ensembl chr 4:63,878,022...63,965,252
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
increases response to substance
ISO
EXP
Diclofenac results in increased expression of TNF mRNA
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[TNF protein co-treated with IFNG protein] promotes the reaction [Diclofenac results in increased activity of CASP3 protein]]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [TNF protein promotes the reaction [Diclofenac results in increased activity of CASP3 protein]]; 2-aminoethoxydiphenyl borate inhibits the reaction [[TNF protein co-treated with IFNG protein] promotes the reaction [Diclofenac results in increased activity of CASP3 protein]]; 2-aminoethoxydiphenyl borate inhibits the reaction [TNF protein promotes the reaction [Diclofenac results in increased activity of CASP3 protein]]; [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Diclofenac; [TNF protein co-treated with Diclofenac] results in increased activity of CASP8 protein; [TNF protein co-treated with Diclofenac] results in increased activity of CASP9 protein; [TNF protein co-treated with Diclofenac] results in increased phosphorylation of EIF2S1 protein; [TNF protein co-treated with IFNG protein] promotes the reaction [Diclofenac affects the abundance of Calcium]; [TNF protein co-treated with IFNG protein] promotes the reaction [Diclofenac results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[TNF protein co-treated with Diclofenac] results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [[TNF protein co-treated with Diclofenac] results in increased activity of CASP9 protein]; benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [[TNF protein co-treated with Diclofenac] results in increased activity of CASP8 protein]; benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [[TNF protein co-treated with Diclofenac] results in increased activity of CASP9 protein]; Diclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; Diclofenac inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Diclofenac inhibits the reaction [TNF protein results in increased activity of CHUK protein]; Diclofenac inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]; Diclofenac inhibits the reaction [TNF protein results in increased activity of RELA protein]; Diclofenac inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; Diclofenac inhibits the reaction [TNF protein results in increased expression of CCND1 protein]; Diclofenac inhibits the reaction [TNF protein results in increased expression of CRP mRNA]; Diclofenac inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; Diclofenac inhibits the reaction [TNF protein results in increased expression of ITGB3 protein]; Diclofenac inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]; Diclofenac inhibits the reaction [TNF protein results in increased secretion of CRP protein]; Diclofenac inhibits the reaction [TNF protein results in increased secretion of CXCL8 protein]; Diclofenac promotes the reaction [Mustard Gas results in increased secretion of TNF protein]; TNF protein promotes the reaction [Diclofenac results in increased activity of CASP3 protein]
TNF protein results in increased susceptibility to Diclofenac
Diclofenac results in increased expression of TNF mRNA; Diclofenac results in increased expression of TNF protein
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; [Water deficiency co-treated with Diclofenac] results in increased expression of TNF protein; Acetylcysteine inhibits the reaction [Diclofenac results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Diclofenac results in increased expression of TNF protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; Diclofenac inhibits the reaction [Freund's Adjuvant results in increased expression of TNF protein]; Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in decreased expression of NFKBIA protein]; Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]; Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 protein]; Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein]; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in increased expression of TNF protein]; RELA mutant form inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; Silymarin inhibits the reaction [Diclofenac results in increased expression of TNF mRNA]; Silymarin inhibits the reaction [Diclofenac results in increased expression of TNF protein]; SN50 peptide inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]
[Diclofenac co-treated with Lipopolysaccharides] results in increased secretion of TNF protein; Diclofenac inhibits the reaction [Freund's Adjuvant results in increased expression of TNF protein]
CTD PMID:15135310 PMID:15489888 PMID:17328244 PMID:19022234 PMID:19362101 More... NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 decreases expression ISO Diclofenac results in decreased expression of TNFAIP3 mRNA CTD PMID:21873647 NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405
JBrowse link
G Tnfaip8l2 tumor necrosis factor, alpha-induced protein 8-like 2 increases expression EXP Diclofenac results in increased expression of TNFAIP8L2 mRNA CTD PMID:26934552 NCBI chr 3:95,046,832...95,051,581
Ensembl chr 3:95,046,832...95,049,671
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a affects expression
increases expression
ISO
EXP
Diclofenac affects the expression of TNFRSF1A mRNA
Diclofenac results in increased expression of TNFRSF1A mRNA
CTD PMID:24752500 PMID:26934552 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
JBrowse link
G Tnfsf18 tumor necrosis factor (ligand) superfamily, member 18 decreases expression EXP Diclofenac results in decreased expression of TNFSF18 mRNA CTD PMID:35537566 NCBI chr 1:161,322,221...161,333,903
Ensembl chr 1:161,322,224...161,332,859
JBrowse link
G Tnks1bp1 tankyrase 1 binding protein 1 decreases expression EXP Diclofenac results in decreased expression of TNKS1BP1 mRNA CTD PMID:35537566 NCBI chr 2:84,878,356...84,903,392
Ensembl chr 2:84,878,366...84,903,392
JBrowse link
G Tnp1 transition protein 1 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of TNP1 mRNA CTD PMID:37844793 NCBI chr 1:73,054,233...73,055,058
Ensembl chr 1:73,054,233...73,055,068
JBrowse link
G Tnp2 transition protein 2 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of TNP2 mRNA CTD PMID:37844793 NCBI chr16:10,605,799...10,606,519
Ensembl chr16:10,605,800...10,606,524
JBrowse link
G Togaram2 TOG array regulator of axonemal microtubules 2 increases expression ISO Diclofenac results in increased expression of TOGARAM2 mRNA CTD PMID:30723492 NCBI chr17:71,980,153...72,036,666
Ensembl chr17:71,980,256...72,036,664
JBrowse link
G Tox thymocyte selection-associated high mobility group box increases expression ISO Diclofenac results in increased expression of TOX mRNA CTD PMID:30723492 NCBI chr 4:6,686,353...6,991,557
Ensembl chr 4:6,686,353...6,991,557
JBrowse link
G Tpd52 tumor protein D52 increases expression ISO Diclofenac results in increased expression of TPD52 mRNA CTD PMID:21873647 NCBI chr 3:8,991,590...9,069,824
Ensembl chr 3:8,990,653...9,069,783
JBrowse link
G Tppp2 tubulin polymerization-promoting protein family member 2 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of TPPP2 mRNA CTD PMID:37844793 NCBI chr14:52,155,887...52,158,161
Ensembl chr14:52,155,882...52,158,157
JBrowse link
G Tpsb2 tryptase beta 2 increases expression ISO Diclofenac results in increased expression of TPSB2 mRNA CTD PMID:30723492 NCBI chr17:25,585,282...25,587,070
Ensembl chr17:25,585,170...25,588,079
JBrowse link
G Traf3ip3 TRAF3 interacting protein 3 increases expression ISO Diclofenac results in increased expression of TRAF3IP3 mRNA CTD PMID:30723492 NCBI chr 1:192,857,812...192,883,854
Ensembl chr 1:192,857,761...192,884,011
JBrowse link
G Trat1 T cell receptor associated transmembrane adaptor 1 increases expression EXP Diclofenac results in increased expression of TRAT1 mRNA CTD PMID:26934552 NCBI chr16:48,551,137...48,630,883
Ensembl chr16:48,551,137...48,592,384
JBrowse link
G Trib3 tribbles pseudokinase 3 decreases expression EXP Diclofenac results in decreased expression of TRIB3 mRNA CTD PMID:26934552 PMID:35537566 NCBI chr 2:152,179,345...152,185,980
Ensembl chr 2:152,179,342...152,185,952
JBrowse link
G Trim46 tripartite motif-containing 46 decreases expression EXP Diclofenac results in decreased expression of TRIM46 mRNA CTD PMID:35537566 NCBI chr 3:89,141,476...89,153,655
Ensembl chr 3:89,141,484...89,153,616
JBrowse link
G Trp53 transformation related protein 53 multiple interactions
increases expression
affects expression
EXP
ISO
Diclofenac promotes the reaction [Doxorubicin results in increased expression of TRP53 protein]
Diclofenac results in increased expression of TP53 mRNA; Diclofenac results in increased expression of TP53 protein
Diclofenac affects the expression of TP53 mRNA
CTD PMID:15458769 PMID:24752500 PMID:29027214 PMID:32087850 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Trp53inp1 transformation related protein 53 inducible nuclear protein 1 increases expression EXP Diclofenac results in increased expression of TRP53INP1 mRNA CTD PMID:26934552 PMID:35537566 NCBI chr 4:11,156,441...11,174,379
Ensembl chr 4:11,156,431...11,174,379
JBrowse link
G Trrap transformation/transcription domain-associated protein multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in increased expression of TRRAP mRNA CTD PMID:37844793 NCBI chr 5:144,704,547...144,796,588
Ensembl chr 5:144,704,542...144,796,588
JBrowse link
G Try4 trypsin 4 decreases expression EXP Diclofenac results in decreased expression of PRSS3 mRNA CTD PMID:26934552 NCBI chr 6:41,279,206...41,282,467
Ensembl chr 6:41,279,203...41,282,466
JBrowse link
G Tsc1 TSC complex subunit 1 affects expression ISO Diclofenac affects the expression of TSC1 mRNA CTD PMID:24752500 NCBI chr 2:28,531,005...28,581,183
Ensembl chr 2:28,531,240...28,581,179
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 decreases expression EXP Diclofenac results in decreased expression of TSC22D1 mRNA CTD PMID:26934552 NCBI chr14:76,652,401...76,745,205
Ensembl chr14:76,652,401...76,745,205
JBrowse link
G Tsc22d2 TSC22 domain family, member 2 increases expression EXP Diclofenac results in increased expression of TSC22D2 mRNA CTD PMID:26934552 NCBI chr 3:58,322,123...58,374,208
Ensembl chr 3:58,322,136...58,374,204
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 increases expression
decreases expression
EXP Diclofenac results in increased expression of TSC22D3 mRNA
Diclofenac results in decreased expression of TSC22D3 mRNA
CTD PMID:26934552 PMID:35537566 NCBI chr  X:139,440,277...139,501,257
Ensembl chr  X:139,440,277...139,501,408
JBrowse link
G Tsks testis-specific serine kinase substrate increases expression ISO Diclofenac results in increased expression of TSKS mRNA CTD PMID:30723492 NCBI chr 7:44,579,044...44,607,465
Ensembl chr 7:44,592,628...44,607,459
JBrowse link
G Tspan4 tetraspanin 4 increases expression EXP Diclofenac results in increased expression of TSPAN4 mRNA CTD PMID:26934552 NCBI chr 7:141,055,194...141,073,340
Ensembl chr 7:141,055,153...141,073,340
JBrowse link
G Tspan8 tetraspanin 8 increases expression EXP Diclofenac results in increased expression of TSPAN8 mRNA CTD PMID:26934552 NCBI chr10:115,652,722...115,685,798
Ensembl chr10:115,652,737...115,685,798
JBrowse link
G Tspear thrombospondin type laminin G domain and EAR repeats increases expression ISO Diclofenac results in increased expression of TSPEAR mRNA CTD PMID:30723492 NCBI chr10:77,521,942...77,722,844
Ensembl chr10:77,522,403...77,722,855
JBrowse link
G Ttr transthyretin increases expression EXP Diclofenac results in increased expression of TTR protein CTD PMID:23506792 NCBI chr18:20,797,266...20,807,383
Ensembl chr18:20,798,337...20,807,378
JBrowse link
G Tuba1a tubulin, alpha 1A affects expression ISO Diclofenac affects the expression of TUBA1A mRNA CTD PMID:24752500 NCBI chr15:98,847,728...98,851,382
Ensembl chr15:98,847,718...98,851,584
JBrowse link
G Tuba1c tubulin, alpha 1C affects expression ISO Diclofenac affects the expression of TUBA1C mRNA CTD PMID:24752500 NCBI chr15:98,927,772...98,935,986
Ensembl chr15:98,927,772...98,935,991
JBrowse link
G Tuba3a tubulin, alpha 3A affects expression ISO Diclofenac affects the expression of TUBA3C mRNA CTD PMID:24752500 NCBI chr 6:125,255,233...125,263,044
Ensembl chr 6:125,255,237...125,263,005
JBrowse link
G Tubb3 tubulin, beta 3 class III affects expression ISO Diclofenac affects the expression of TUBB3 mRNA CTD PMID:24752500 NCBI chr 8:124,138,292...124,148,754
Ensembl chr 8:124,138,163...124,148,754
JBrowse link
G Tubb4b tubulin, beta 4B class IVB affects expression ISO Diclofenac affects the expression of TUBB4B mRNA CTD PMID:24752500 NCBI chr 2:25,112,170...25,114,714
Ensembl chr 2:25,112,172...25,114,714
JBrowse link
G Txn1 thioredoxin 1 increases expression
multiple interactions
ISO Diclofenac results in increased expression of TXN mRNA
[Diclofenac co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TXN1 protein; Diclofenac inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TXN1 mRNA]; Diclofenac inhibits the reaction [Poly I-C results in increased expression of TXN1 mRNA]
CTD PMID:19022234 PMID:23939143 PMID:25772430 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411
JBrowse link
G Txn2 thioredoxin 2 increases expression ISO Diclofenac results in increased expression of TXN2 mRNA CTD PMID:19022234 NCBI chr15:77,799,251...77,813,194
Ensembl chr15:77,799,247...77,813,206
JBrowse link
G Txnip thioredoxin interacting protein increases expression ISO Diclofenac results in increased expression of TXNIP mRNA CTD PMID:19192274 NCBI chr 3:96,465,273...96,469,173
Ensembl chr 3:96,465,273...96,469,199
JBrowse link
G Txnrd1 thioredoxin reductase 1 affects expression
multiple interactions
ISO Diclofenac affects the expression of TXNRD1 mRNA
[Diclofenac co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TXNRD1 protein
CTD PMID:24752500 PMID:25772430 NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546
JBrowse link
G Tyr tyrosinase decreases expression EXP Diclofenac results in decreased expression of TYR protein CTD PMID:21079976 NCBI chr 7:87,073,979...87,142,637
Ensembl chr 7:87,073,979...87,142,720
JBrowse link
G Tyrobp TYRO protein tyrosine kinase binding protein increases expression EXP Diclofenac results in increased expression of TYROBP mRNA CTD PMID:26934552 NCBI chr 7:30,113,207...30,117,007
Ensembl chr 7:30,113,185...30,117,010
JBrowse link
G Ubc ubiquitin C affects expression EXP Diclofenac affects the expression of UBC mRNA CTD PMID:26934552 NCBI chr 5:125,463,029...125,467,081
Ensembl chr 5:125,463,029...125,467,266
JBrowse link
G Ube2b ubiquitin-conjugating enzyme E2B multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of UBE2B mRNA CTD PMID:37844793 NCBI chr11:51,875,965...51,894,972
Ensembl chr11:51,876,324...51,891,589
JBrowse link
G Uck2 uridine-cytidine kinase 2 affects expression ISO Diclofenac affects the expression of UCK2 mRNA CTD PMID:24752500 NCBI chr 1:167,050,464...167,112,657
Ensembl chr 1:167,050,452...167,112,889
JBrowse link
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) increases expression EXP Diclofenac results in increased expression of UCP2 mRNA CTD PMID:26934552 NCBI chr 7:100,142,565...100,148,832
Ensembl chr 7:100,142,544...100,151,227
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 increases expression
multiple interactions
decreases expression
decreases activity
ISO Diclofenac results in increased expression of UGT1A1 mRNA
Diclofenac inhibits the reaction [[UGT1A1 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]; Diclofenac inhibits the reaction [UGT1A1 protein results in increased glucuronidation of Hymecromone]
Diclofenac results in decreased expression of UGT1A1 mRNA
Diclofenac results in decreased activity of UGT1A1 protein
CTD PMID:15334623 PMID:15593333 PMID:18227147 PMID:19022234 PMID:33290829 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719
JBrowse link
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 affects expression
increases glucuronidation
ISO Diclofenac affects the expression of UGT1A10 mRNA
UGT1A10 protein results in increased glucuronidation of Diclofenac
CTD PMID:15117964 PMID:19022234 PMID:22265884 NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 decreases activity
increases glucuronidation
ISO Diclofenac results in decreased activity of UGT1A3 protein
UGT1A3 protein results in increased glucuronidation of Diclofenac
CTD PMID:15117964 PMID:15334623 PMID:15843492 NCBI chr 1:88,128,333...88,147,724
Ensembl chr 1:88,128,323...88,146,719
JBrowse link
G Ugt1a5 UDP glucuronosyltransferase 1 family, polypeptide A5 increases glucuronidation ISO UGT1A4 protein results in increased glucuronidation of Diclofenac CTD PMID:15843492 NCBI chr 1:88,093,734...88,147,724
Ensembl chr 1:88,093,734...88,146,719
JBrowse link
G Ugt1a6b UDP glucuronosyltransferase 1 family, polypeptide A6B multiple interactions ISO Diclofenac inhibits the reaction [[UGT1A6 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]; Diclofenac inhibits the reaction [UGT1A6 protein results in increased glucuronidation of 1-naphthol]; Diclofenac inhibits the reaction [UGT1A6 protein results in increased glucuronidation of Hymecromone] CTD PMID:22265884 PMID:33290829 NCBI chr 1:88,030,979...88,146,720
Ensembl chr 1:88,030,974...88,146,725
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 increases glucuronidation
multiple interactions
ISO UGT1A9 protein results in increased glucuronidation of Diclofenac
Diclofenac inhibits the reaction [[UGT1A9 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]; Diclofenac inhibits the reaction [UGT1A9 protein results in increased glucuronidation of Hymecromone]
CTD PMID:15988124 PMID:33290829 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 increases glucuronidation ISO UGT2B17 protein results in increased glucuronidation of Diclofenac CTD PMID:15843492 PMID:22265884 NCBI chr 5:87,064,498...87,074,362
Ensembl chr 5:87,064,497...87,074,389
JBrowse link
G Ugt2b34 UDP glucuronosyltransferase 2 family, polypeptide B34 multiple interactions
increases glucuronidation
affects response to substance
increases metabolic processing
affects glucuronidation
ISO [CYP3A4 protein co-treated with CYP2C9 protein co-treated with UGT2B7 protein] results in increased susceptibility to Diclofenac; [UGT2B7 protein polymorphism affects the glucuronidation of Diclofenac] which affects the chemical synthesis of 1-O-(2-((2',6'-dichlorophenyl)amino)phenylacetyl)glucopyranuronic acid; Diclofenac inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Diclofenac inhibits the reaction [UGT2B7 protein results in increased glucuronidation of Aldosterone]; Diclofenac inhibits the reaction [UGT2B7 protein results in increased glucuronidation of denopamine]
UGT2B7 protein results in increased glucuronidation of Diclofenac
UGT2B7 protein polymorphism affects the susceptibility to Diclofenac
UGT2B7 protein results in increased metabolism of Diclofenac
CTD PMID:15608137 PMID:15843492 PMID:15988124 PMID:19740398 PMID:22265884 More... NCBI chr 5:87,037,613...87,054,805
Ensembl chr 5:87,037,626...87,054,796
JBrowse link
G Ugt2b38 UDP glucuronosyltransferase 2 family, polypeptide B38 decreases expression EXP Diclofenac results in decreased expression of UGT2B38 mRNA CTD PMID:26934552 NCBI chr 5:87,557,798...87,572,062
Ensembl chr 5:87,557,801...87,572,062
JBrowse link
G Ulk2 unc-51 like kinase 2 increases expression EXP Diclofenac results in increased expression of ULK2 mRNA CTD PMID:26934552 NCBI chr11:61,666,424...61,750,754
Ensembl chr11:61,666,475...61,745,899
JBrowse link
G Ung uracil DNA glycosylase affects expression
increases expression
ISO
EXP
Diclofenac affects the expression of UNG mRNA
Diclofenac results in increased expression of UNG mRNA
CTD PMID:24752500 PMID:26934552 NCBI chr 5:114,268,427...114,277,382
Ensembl chr 5:114,268,447...114,277,384
JBrowse link
G Upp2 uridine phosphorylase 2 decreases expression EXP Diclofenac results in decreased expression of UPP2 mRNA CTD PMID:26934552 NCBI chr 2:58,456,329...58,685,858
Ensembl chr 2:58,457,310...58,682,983
JBrowse link
G Uqcc2 ubiquinol-cytochrome c reductase complex assembly factor 2 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of UQCC2 mRNA CTD PMID:37844793 NCBI chr17:27,341,639...27,352,865
Ensembl chr17:27,341,637...27,352,890
JBrowse link
G Usp28 ubiquitin specific peptidase 28 increases expression EXP Diclofenac results in increased expression of USP28 mRNA CTD PMID:26934552 NCBI chr 9:48,896,577...48,953,817
Ensembl chr 9:48,896,675...48,953,817
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression EXP Diclofenac results in increased expression of VCAM1 mRNA CTD PMID:26934552 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
G Vcan versican decreases expression EXP Diclofenac results in decreased expression of VCAN mRNA CTD PMID:26934552 NCBI chr13:89,803,429...89,891,146
Ensembl chr13:89,803,431...89,890,628
JBrowse link
G Vcl vinculin affects expression ISO Diclofenac affects the expression of VCL mRNA CTD PMID:24752500 NCBI chr14:20,979,436...21,083,744
Ensembl chr14:20,979,466...21,083,744
JBrowse link
G Vegfa vascular endothelial growth factor A affects expression ISO Diclofenac affects the expression of VEGFA mRNA CTD PMID:24752500 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Vegfc vascular endothelial growth factor C decreases expression EXP Diclofenac results in decreased expression of VEGFC mRNA CTD PMID:35537566 NCBI chr 8:54,530,567...54,639,489
Ensembl chr 8:54,530,641...54,640,131
JBrowse link
G Vim vimentin decreases expression ISO Diclofenac results in decreased expression of VIM protein CTD PMID:19628293 NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637
JBrowse link
G Vldlr very low density lipoprotein receptor decreases expression EXP Diclofenac results in decreased expression of VLDLR mRNA CTD PMID:26934552 NCBI chr19:27,190,070...27,231,631
Ensembl chr19:27,193,884...27,231,631
JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 increases expression EXP Diclofenac results in increased expression of VSIG4 mRNA CTD PMID:26934552 NCBI chr  X:95,290,807...95,337,044
Ensembl chr  X:95,290,809...95,337,044
JBrowse link
G Vwce von Willebrand factor C and EGF domains decreases expression EXP Diclofenac results in decreased expression of VWCE mRNA CTD PMID:26934552 NCBI chr19:10,611,582...10,643,577
Ensembl chr19:10,611,577...10,643,577
JBrowse link
G Wdr11 WD repeat domain 11 decreases expression EXP Diclofenac results in decreased expression of WDR11 mRNA CTD PMID:35537566 NCBI chr 7:129,193,373...129,237,462
Ensembl chr 7:129,193,587...129,237,462
JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 increases expression EXP Diclofenac results in increased expression of WIPI1 mRNA CTD PMID:26934552 NCBI chr11:109,464,347...109,502,215
Ensembl chr11:109,464,157...109,502,793
JBrowse link
G Xbp1 X-box binding protein 1 increases expression EXP Diclofenac results in increased expression of XBP1 mRNA CTD PMID:26934552 NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893
JBrowse link
G Xiap X-linked inhibitor of apoptosis affects expression
increases expression
ISO
EXP
Diclofenac affects the expression of XIAP mRNA
Diclofenac results in increased expression of XIAP mRNA
CTD PMID:24752500 PMID:26934552 NCBI chr  X:41,148,483...41,198,541
Ensembl chr  X:41,148,556...41,198,533
JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide affects expression ISO Diclofenac affects the expression of YWHAB mRNA CTD PMID:24752500 NCBI chr 2:163,837,082...163,860,508
Ensembl chr 2:163,836,880...163,860,508
JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta affects expression ISO Diclofenac affects the expression of YWHAQ mRNA CTD PMID:24752500 NCBI chr12:21,440,330...21,467,437
Ensembl chr12:21,440,072...21,467,638
JBrowse link
G Zar1 zygote arrest 1 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of ZAR1 mRNA CTD PMID:37844793 NCBI chr 5:72,734,457...72,738,427
Ensembl chr 5:72,734,149...72,738,597
JBrowse link
G Zbp1 Z-DNA binding protein 1 increases expression EXP Diclofenac results in increased expression of ZBP1 mRNA CTD PMID:26934552 NCBI chr 2:173,048,405...173,060,715
Ensembl chr 2:173,048,405...173,060,716
JBrowse link
G Zdhhc23 zinc finger, DHHC domain containing 23 increases expression EXP Diclofenac results in increased expression of ZDHHC23 mRNA CTD PMID:35537566 NCBI chr16:43,785,396...43,800,295
Ensembl chr16:43,785,396...43,800,154
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 decreases expression ISO Diclofenac results in decreased expression of ZEB1 protein CTD PMID:19628293 NCBI chr18:5,591,330...5,775,468
Ensembl chr18:5,591,860...5,775,467
JBrowse link
G Zfp346 zinc finger protein 346 decreases expression EXP Diclofenac results in decreased expression of ZFP346 mRNA CTD PMID:35537566 NCBI chr13:55,253,079...55,282,884
Ensembl chr13:55,253,124...55,282,638
JBrowse link
G Zfp420 zinc finger protein 420 decreases expression EXP Diclofenac results in decreased expression of ZFP420 mRNA CTD PMID:35537566 NCBI chr 7:29,559,392...29,576,727
Ensembl chr 7:29,559,404...29,576,717
JBrowse link
G Zfp786 zinc finger protein 786 increases expression ISO Diclofenac results in increased expression of ZFP786 mRNA CTD PMID:30723492 NCBI chr 6:47,792,470...47,817,061
Ensembl chr 6:47,796,200...47,807,801
JBrowse link
G Zfp940 zinc finger protein 940 decreases expression EXP Diclofenac results in decreased expression of ZFP940 mRNA CTD PMID:35537566 NCBI chr 7:29,533,943...29,553,101
Ensembl chr 7:29,533,045...29,553,094
JBrowse link
G Znrd2 zinc ribbon domain containing 2 increases expression EXP Diclofenac results in increased expression of ZNRD2 mRNA CTD PMID:35537566 NCBI chr19:5,780,334...5,781,760
Ensembl chr19:5,780,331...5,781,760
Ensembl chr19:5,780,331...5,781,760
JBrowse link
G Zp1 zona pellucida glycoprotein 1 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of ZP1 mRNA CTD PMID:37844793 NCBI chr19:10,891,660...10,897,965
Ensembl chr19:10,891,651...10,897,996
JBrowse link
G Zp2 zona pellucida glycoprotein 2 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of ZP2 mRNA CTD PMID:37844793 NCBI chr 7:119,725,985...119,744,514
Ensembl chr 7:119,725,995...119,744,514
JBrowse link
G Zp3 zona pellucida glycoprotein 3 multiple interactions EXP [Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of ZP3 mRNA CTD PMID:37844793 NCBI chr 5:136,008,959...136,017,478
Ensembl chr 5:136,008,953...136,017,478
JBrowse link
homovanillic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp9 aquaporin 9 multiple interactions EXP AQP9 gene mutant form inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased abundance of Homovanillic Acid] CTD PMID:29566083 NCBI chr 9:71,017,941...71,075,170
Ensembl chr 9:71,017,941...71,075,964
JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO [tolcapone results in decreased activity of COMT protein] which results in decreased abundance of Homovanillic Acid CTD PMID:11793163 PMID:15190105 PMID:16012872 NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602
JBrowse link
G Maob monoamine oxidase B multiple interactions ISO [Selegiline results in decreased activity of MAOB protein] which results in decreased abundance of Homovanillic Acid CTD PMID:16012872 NCBI chr  X:16,575,520...16,683,605
Ensembl chr  X:16,575,521...16,683,605
JBrowse link
G Nos1 nitric oxide synthase 1, neuronal multiple interactions EXP NOS1 protein affects the reaction [Methamphetamine results in decreased abundance of Homovanillic Acid] CTD PMID:11085313 NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases abundance EXP NR3C1 protein results in increased abundance of Homovanillic Acid CTD PMID:11226678 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474
JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions ISO [beta-funaltrexamine binds to and results in decreased activity of OPRM1 protein] inhibits the reaction [Morphine results in increased abundance of Homovanillic Acid] CTD PMID:8884884 NCBI chr10:6,708,593...6,988,209
Ensembl chr10:6,708,506...6,988,198
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions EXP [PARP1 protein results in increased susceptibility to 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] which results in increased abundance of Homovanillic Acid CTD PMID:10318960 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Sct secretin increases abundance ISO SCT protein results in increased abundance of Homovanillic Acid CTD PMID:16168596 NCBI chr 7:140,858,243...140,859,082
Ensembl chr 7:140,858,243...140,859,046
JBrowse link
G Slc22a8 solute carrier family 22 (organic anion transporter), member 8 multiple interactions ISO Homovanillic Acid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:10224140 NCBI chr19:8,568,576...8,589,199
Ensembl chr19:8,568,618...8,589,199
JBrowse link
G Tfam transcription factor A, mitochondrial decreases abundance EXP TFAM gene mutant form results in decreased abundance of Homovanillic Acid CTD PMID:28595911 NCBI chr10:71,061,298...71,074,157
Ensembl chr10:71,061,294...71,074,110
JBrowse link
G Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor multiple interactions
increases abundance
ISO Calcitriol promotes the reaction [VDR protein results in increased abundance of Homovanillic Acid] CTD PMID:27450565 NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511
JBrowse link
hydratropic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 increases glucuronidation ISO UGT1A10 protein results in increased glucuronidation of hydratropic acid CTD PMID:15117964 NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of hydratropic acid CTD PMID:15117964 NCBI chr 1:88,128,333...88,147,724
Ensembl chr 1:88,128,323...88,146,719
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 increases glucuronidation ISO UGT2B1 protein results in increased glucuronidation of hydratropic acid CTD PMID:8302279 NCBI chr 5:87,064,498...87,074,362
Ensembl chr 5:87,064,497...87,074,389
JBrowse link
indole-3-acetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP-binding cassette, sub-family C member 4 multiple interactions ISO indoleacetic acid inhibits the reaction [ABCC4 protein results in increased export of Methotrexate] CTD PMID:21483698 NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631
JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions
affects localization
ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [indoleacetic acid affects the localization of AHR protein]; AHR protein affects the reaction [indoleacetic acid affects the localization of NFKB1 protein]; AHR protein affects the reaction [indoleacetic acid results in increased expression of F3 mRNA]; AHR protein affects the reaction [indoleacetic acid results in increased expression of F3 protein]; indoleacetic acid promotes the reaction [AHR protein binds to CYP1A1 promoter]; indoleacetic acid promotes the reaction [AHR protein binds to CYP1B1 promoter]; indoleacetic acid results in increased activity of [AHR protein binds to ARNT protein] CTD PMID:9407059 PMID:30324315 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO indoleacetic acid results in increased activity of [AHR protein binds to ARNT protein] CTD PMID:9407059 NCBI chr 3:95,341,674...95,404,551
Ensembl chr 3:95,341,699...95,404,551
JBrowse link
G Cat catalase multiple interactions
decreases expression
EXP
ISO
indoleacetic acid inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; indoleacetic acid inhibits the reaction [Diethylnitrosamine results in decreased expression of CAT mRNA]
indoleacetic acid results in decreased expression of CAT protein
CTD PMID:19107877 PMID:38555004 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Col3a1 collagen, type III, alpha 1 increases expression ISO indoleacetic acid results in increased expression of COL3A1 mRNA CTD PMID:38555004 NCBI chr 1:45,350,698...45,388,866
Ensembl chr 1:45,350,698...45,388,866
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [indoleacetic acid results in increased expression of CYP1A1 mRNA]; indoleacetic acid promotes the reaction [AHR protein binds to CYP1A1 promoter] CTD PMID:30324315 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression
multiple interactions
ISO indoleacetic acid results in increased expression of CYP1B1 mRNA
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [indoleacetic acid results in increased expression of CYP1B1 mRNA]; indoleacetic acid promotes the reaction [AHR protein binds to CYP1B1 promoter]
CTD PMID:30324315 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G F3 coagulation factor III, tissue factor increases expression
multiple interactions
ISO indoleacetic acid results in increased expression of F3 mRNA; indoleacetic acid results in increased expression of F3 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [indoleacetic acid results in increased expression of F3 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [indoleacetic acid results in increased expression of F3 protein]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [indoleacetic acid results in increased expression of F3 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [indoleacetic acid results in increased expression of F3 protein]; AHR protein affects the reaction [indoleacetic acid results in increased expression of F3 mRNA]; AHR protein affects the reaction [indoleacetic acid results in increased expression of F3 protein]; bisindolylmaleimide I inhibits the reaction [indoleacetic acid results in increased expression of F3 mRNA]; bisindolylmaleimide I inhibits the reaction [indoleacetic acid results in increased expression of F3 protein]; Dactinomycin inhibits the reaction [indoleacetic acid results in increased expression of F3 mRNA]; SB 203580 inhibits the reaction [indoleacetic acid results in increased expression of F3 mRNA]; SB 203580 inhibits the reaction [indoleacetic acid results in increased expression of F3 protein]
CTD PMID:30324315 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP indoleacetic acid inhibits the reaction [Diethylnitrosamine results in decreased expression of GPX1 mRNA] CTD PMID:19107877 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Gsr glutathione reductase multiple interactions EXP indoleacetic acid inhibits the reaction [Diethylnitrosamine results in decreased expression of GSR mRNA] CTD PMID:19107877 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
JBrowse link
G Ifng interferon gamma increases expression EXP indoleacetic acid results in increased expression of IFNG CTD PMID:20728597 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Il2 interleukin 2 increases expression EXP indoleacetic acid results in increased expression of IL2 CTD PMID:20728597 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il2ra interleukin 2 receptor, alpha chain increases expression EXP indoleacetic acid results in increased expression of IL2RA CTD PMID:20728597 NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004
JBrowse link
G Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta increases expression ISO indoleacetic acid results in increased expression of MYH7 mRNA CTD PMID:38555004 NCBI chr14:55,208,141...55,232,083
Ensembl chr14:55,208,141...55,232,083
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions
increases expression
affects localization
ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [indoleacetic acid affects the localization of NFKB1 protein]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [indoleacetic acid affects the localization of NFKB1 protein]; AHR protein affects the reaction [indoleacetic acid affects the localization of NFKB1 protein]; SB 203580 inhibits the reaction [indoleacetic acid affects the localization of NFKB1 protein]
indoleacetic acid results in increased expression of NFKB1 mRNA
CTD PMID:30324315 PMID:38555004 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Nppa natriuretic peptide type A increases expression ISO indoleacetic acid results in increased expression of NPPA mRNA CTD PMID:38555004 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536
JBrowse link
G Nppb natriuretic peptide type B increases expression ISO indoleacetic acid results in increased expression of NPPB mRNA CTD PMID:38555004 NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) affects localization ISO indoleacetic acid affects the localization of RELA protein CTD PMID:30324315 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 increases expression ISO indoleacetic acid results in increased expression of SLC10A1 mRNA CTD PMID:30639138 NCBI chr12:80,999,959...81,015,479
Ensembl chr12:80,999,957...81,015,479
JBrowse link
G Sod1 superoxide dismutase 1, soluble multiple interactions EXP indoleacetic acid inhibits the reaction [Diethylnitrosamine results in decreased expression of SOD1 mRNA] CTD PMID:19107877 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Tnf tumor necrosis factor increases expression EXP indoleacetic acid results in increased expression of TNF CTD PMID:20728597 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnni3 troponin I, cardiac 3 increases expression ISO indoleacetic acid results in increased expression of TNNI3 protein CTD PMID:38555004 NCBI chr 7:4,521,304...4,526,228
Ensembl chr 7:4,521,304...4,527,228
JBrowse link
indole-3-butyric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO indolebutyric acid results in decreased activity of ACHE protein CTD PMID:19442822 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Ada adenosine deaminase decreases activity ISO indolebutyric acid results in decreased activity of ADA protein CTD PMID:19442822 NCBI chr 2:163,565,703...163,592,154
Ensembl chr 2:163,568,504...163,592,159
JBrowse link
G Bche butyrylcholinesterase decreases activity ISO indolebutyric acid results in decreased activity of BCHE protein CTD PMID:19442822 NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748
JBrowse link
G Mpo myeloperoxidase increases activity ISO indolebutyric acid results in increased activity of MPO protein CTD PMID:19442822 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha increases expression ISO indolebutyric acid analog results in increased expression of NFKBIA protein CTD PMID:23499788 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases cleavage ISO indolebutyric acid analog results in increased cleavage of PARP1 protein CTD PMID:23499788 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
phenylacetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP-binding cassette, sub-family C member 4 multiple interactions ISO phenylacetic acid inhibits the reaction [ABCC4 protein results in increased export of Methotrexate] CTD PMID:21483698 NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631
JBrowse link
G Pon1 paraoxonase 1 multiple interactions
affects metabolic processing
increases hydrolysis
decreases hydrolysis
ISO 4-hydroxy-2-nonenal inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid]; [Ascorbic Acid co-treated with Copper Sulfate] inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid]; [Ascorbic Acid co-treated with ferrous sulfate] inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid]; Arachidonic Acid inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid]; Hydrogen Peroxide inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid]; Linoleic Acid inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid]; Pyruvaldehyde inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid]
PON1 protein affects the metabolism of phenylacetic acid; PON1 protein polymorphism affects the metabolism of phenylacetic acid
fluvastatin inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid]
PON1 promoter SNP results in decreased hydrolysis of phenylacetic acid
CTD PMID:9746266 PMID:11304470 PMID:14668577 PMID:15375178 PMID:15924216 More... NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946
JBrowse link
G Pon2 paraoxonase 2 increases hydrolysis
decreases hydrolysis
ISO PON2 protein results in increased hydrolysis of phenylacetic acid
PON2 protein SNP results in decreased hydrolysis of phenylacetic acid
CTD PMID:16117861 NCBI chr 6:5,264,620...5,298,408
Ensembl chr 6:5,264,147...5,298,455
JBrowse link
G Pon3 paraoxonase 3 increases hydrolysis ISO PON3 protein results in increased hydrolysis of phenylacetic acid CTD PMID:16099434 PMID:16139510 NCBI chr 6:5,216,253...5,256,236
Ensembl chr 6:5,220,852...5,256,286
JBrowse link
G Slc22a7 solute carrier family 22 (organic anion transporter), member 7 multiple interactions ISO phenylacetic acid promotes the reaction [SLC22A7 protein results in increased export of Orotic Acid] CTD PMID:22981274 NCBI chr17:46,743,111...46,749,403
Ensembl chr17:46,743,109...46,749,383
JBrowse link
picloram term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cux1 cut-like homeobox 1 multiple interactions ISO [Herbicides results in increased abundance of Picloram] which affects the methylation of CUX1 gene CTD PMID:34516295 NCBI chr 5:136,276,989...136,596,429
Ensembl chr 5:136,276,989...136,596,344
JBrowse link
G Foxo1 forkhead box O1 decreases expression
multiple interactions
EXP Picloram results in decreased expression of FOXO1 mRNA
arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [Picloram results in decreased expression of FOXO1 mRNA]
CTD PMID:21318024 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
JBrowse link
G Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) decreases expression
multiple interactions
EXP Picloram results in decreased expression of GRIN1 mRNA
arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [Picloram results in decreased expression of GRIN1 mRNA]
CTD PMID:21318024 NCBI chr 2:25,181,189...25,209,199
Ensembl chr 2:25,181,193...25,209,199
JBrowse link
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A multiple interactions ISO [Herbicides results in increased abundance of Picloram] which affects the methylation of HTR2A gene CTD PMID:34516295 NCBI chr14:74,878,314...74,944,299
Ensembl chr14:74,878,280...74,946,934
JBrowse link
G Mettl15 methyltransferase like 15 multiple interactions ISO [Herbicides results in increased abundance of Picloram] which affects the methylation of METTL15 gene CTD PMID:34516295 NCBI chr 2:108,922,642...109,111,100
Ensembl chr 2:108,922,642...109,111,093
JBrowse link
G Msra methionine sulfoxide reductase A multiple interactions ISO [Herbicides results in increased abundance of Picloram] which affects the methylation of MSRA gene CTD PMID:34516295 NCBI chr14:64,360,070...64,693,352
Ensembl chr14:64,360,074...64,693,352
JBrowse link
G mt-Atp6 ATP synthase 6, mitochondrial multiple interactions
decreases expression
EXP arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [Picloram results in decreased expression of ATP6 mRNA] CTD PMID:21318024 NCBI chr MT:7,927...8,607
Ensembl chr MT:7,927...8,607
JBrowse link
G mt-Co1 cytochrome c oxidase I, mitochondrial decreases expression
multiple interactions
EXP Picloram results in decreased expression of COX1 mRNA
arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [Picloram results in decreased expression of COX1 mRNA]
CTD PMID:21318024 NCBI chr MT:5,328...6,872
Ensembl chr MT:5,328...6,872
JBrowse link
G mt-Cytb cytochrome b, mitochondrial multiple interactions
decreases expression
EXP arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [Picloram results in decreased expression of CYTB mRNA] CTD PMID:21318024 NCBI chr MT:14,145...15,288
Ensembl chr MT:14,145...15,288
JBrowse link
G mt-Nd1 NADH dehydrogenase 1, mitochondrial multiple interactions
decreases expression
EXP arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of ND1 mRNA] CTD PMID:21318024 NCBI chr MT:2,751...3,707
Ensembl chr MT:2,751...3,707
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha increases expression EXP Picloram results in increased expression of PPARGC1A mRNA CTD PMID:21318024 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions
decreases expression
EXP arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX1 mRNA] CTD PMID:21318024 NCBI chr 4:116,542,796...116,557,196
Ensembl chr 4:116,542,741...116,558,019
JBrowse link
G Prdx2 peroxiredoxin 2 multiple interactions
decreases expression
EXP arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX2 mRNA] CTD PMID:21318024 NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463
JBrowse link
G Prdx3 peroxiredoxin 3 multiple interactions
decreases expression
EXP arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX3 mRNA] CTD PMID:21318024 NCBI chr19:60,852,504...60,862,976
Ensembl chr19:60,852,489...60,862,994
JBrowse link
G Prdx4 peroxiredoxin 4 multiple interactions
decreases expression
EXP arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX4 mRNA] CTD PMID:21318024 NCBI chr  X:154,106,914...154,125,268
Ensembl chr  X:154,106,914...154,123,750
JBrowse link
G Prdx5 peroxiredoxin 5 decreases expression
multiple interactions
EXP Picloram results in decreased expression of PRDX5 mRNA
arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX5 mRNA]
CTD PMID:21318024 NCBI chr19:6,884,065...6,887,474
Ensembl chr19:6,884,065...6,887,474
JBrowse link
G Prdx6 peroxiredoxin 6 multiple interactions
decreases expression
EXP arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX6 mRNA] CTD PMID:21318024 NCBI chr 1:161,067,682...161,078,780
Ensembl chr 1:161,067,682...161,078,789
JBrowse link
G Tbc1d32 TBC1 domain family, member 32 multiple interactions ISO [Herbicides results in increased abundance of Picloram] which affects the methylation of TBC1D32 gene CTD PMID:34516295 NCBI chr10:55,890,389...56,106,495
Ensembl chr10:55,890,389...56,104,785
JBrowse link
scopolamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A decreases expression ISO Scopolamine results in decreased expression of ABCB1 mRNA CTD PMID:12818353 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 increases expression ISO Scopolamine results in increased expression of ABCG1 mRNA CTD PMID:12818353 NCBI chr17:31,276,668...31,336,958
Ensembl chr17:31,276,649...31,336,962
JBrowse link
G Ache acetylcholinesterase multiple interactions
increases expression
affects activity
increases activity
decreases activity
decreases expression
increases response to substance
affects response to substance
ISO
EXP
kangshuai yizhi inhibits the reaction [Scopolamine results in increased activity of ACHE protein]
Scopolamine results in increased expression of ACHE mRNA; Scopolamine results in increased expression of ACHE protein
Scopolamine affects the activity of ACHE protein
Scopolamine results in decreased activity of ACHE protein
Ascorbic Acid inhibits the reaction [Scopolamine results in decreased activity of ACHE protein]; Canagliflozin inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; Galantamine inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; stevioside inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; Vitamin E inhibits the reaction [Scopolamine results in decreased activity of ACHE protein]
Scopolamine results in decreased expression of ACHE protein
ACHE protein results in increased susceptibility to Scopolamine
7-fluoro-1,3-diphenylisoquinoline-1-amine inhibits the reaction [Scopolamine results in increased expression of ACHE protein]; acanthoside B inhibits the reaction [Scopolamine results in increased expression of ACHE protein]; ajoene inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; chong-myung-tang inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; dihydroactinidiolide inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; Donepezil inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; mangiferin inhibits the reaction [Scopolamine results in decreased expression of ACHE protein]; Piracetam inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; Plant Extracts affects the reaction [Scopolamine affects the activity of ACHE protein]; Plant Extracts inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; Plant Extracts inhibits the reaction [Scopolamine results in increased expression of ACHE mRNA]; polygalacic acid inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; protopanaxadiol inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; Serotonin analog inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; Tacrine inhibits the reaction [Scopolamine results in increased expression of ACHE protein]
ACHE affects the susceptibility to Scopolamine
CTD PMID:11814146 PMID:15301936 PMID:18533140 PMID:18672024 PMID:20673844 More... NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Adora3 adenosine A3 receptor multiple interactions EXP [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine binds to and results in increased activity of ADORA3 protein] which results in decreased susceptibility to Scopolamine CTD PMID:12672554 NCBI chr 3:105,811,737...105,816,244
Ensembl chr 3:105,778,174...105,816,242
JBrowse link
G Agt angiotensinogen multiple interactions ISO [AGT protein modified form binds to and results in decreased activity of LNPEP protein] which results in decreased susceptibility to Scopolamine CTD PMID:11707427 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 decreases phosphorylation ISO Scopolamine results in decreased phosphorylation of AKT1 protein CTD PMID:27346436 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Apba1 amyloid beta precursor protein binding family A member 1 increases expression ISO Scopolamine results in increased expression of APBA1 mRNA CTD PMID:12818353 NCBI chr19:23,736,170...23,926,961
Ensembl chr19:23,736,251...23,926,960
JBrowse link
G Aplp2 amyloid beta precursor-like protein 2 increases expression ISO Scopolamine results in increased expression of APLP2 mRNA CTD PMID:12818353 NCBI chr 9:31,060,853...31,123,144
Ensembl chr 9:31,060,853...31,123,111
JBrowse link
G App amyloid beta precursor protein decreases cleavage EXP Scopolamine results in decreased cleavage of APP protein CTD PMID:16423497 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
JBrowse link
G Arc activity regulated cytoskeletal-associated protein decreases expression
decreases expression
ISO
EXP
Scopolamine results in decreased expression of ARC mRNA
scopolamine decreases expression of Arc mRNA and protein in cerebral cortex and hippocampus
CTD
RGD
PMID:17540011 PMID:24012642 RGD:401938610 NCBI chr15:74,540,930...74,544,419
Ensembl chr15:74,540,932...74,544,419
JBrowse link
G Arg2 arginase type II decreases expression ISO Scopolamine results in decreased expression of ARG2 mRNA CTD PMID:12818353 NCBI chr12:79,177,562...79,203,075
Ensembl chr12:79,177,551...79,203,075
JBrowse link
G Arl4d ADP-ribosylation factor-like 4D decreases expression ISO Scopolamine results in decreased expression of ARL4D mRNA CTD PMID:17540011 NCBI chr11:101,556,367...101,558,658
Ensembl chr11:101,556,367...101,558,658
JBrowse link
G Avp arginine vasopressin multiple interactions ISO [[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine CTD PMID:11553362 NCBI chr 2:130,422,540...130,424,508
Ensembl chr 2:130,422,540...130,424,474
JBrowse link
G Avpr1a arginine vasopressin receptor 1A multiple interactions ISO [[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine CTD PMID:11553362 NCBI chr10:122,284,404...122,289,358
Ensembl chr10:122,284,404...122,289,357
JBrowse link
G Bax BCL2-associated X protein increases expression
multiple interactions
EXP
ISO
Scopolamine results in increased expression of BAX mRNA; Scopolamine results in increased expression of BAX protein
Galantamine inhibits the reaction [Scopolamine results in increased expression of BAX protein]; intybin inhibits the reaction [Scopolamine results in increased expression of BAX protein]
dihydroactinidiolide inhibits the reaction [Scopolamine results in increased expression of BAX protein]; Donepezil inhibits the reaction [Scopolamine results in increased expression of BAX protein]; Plant Extracts inhibits the reaction [Scopolamine results in increased expression of BAX mRNA]
CTD PMID:17120751 PMID:26434561 PMID:27346436 PMID:34371027 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcat1 branched chain aminotransferase 1, cytosolic increases expression ISO Scopolamine results in increased expression of BCAT1 mRNA CTD PMID:17540011 NCBI chr 6:144,939,561...145,021,883
Ensembl chr 6:144,939,561...145,021,910
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression
multiple interactions
EXP
ISO
Scopolamine results in decreased expression of BCL2 mRNA; Scopolamine results in decreased expression of BCL2 protein
Galantamine inhibits the reaction [Scopolamine results in decreased expression of BCL2 protein]; intybin inhibits the reaction [Scopolamine results in decreased expression of BCL2 protein]
dihydroactinidiolide inhibits the reaction [Scopolamine results in decreased expression of BCL2 protein]; Donepezil inhibits the reaction [Scopolamine results in decreased expression of BCL2 protein]
CTD PMID:17120751 PMID:26434561 PMID:27346436 PMID:34371027 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bdnf brain derived neurotrophic factor multiple interactions
decreases expression
ISO
EXP
Scopolamine inhibits the reaction [Dizocilpine Maleate affects the expression of BDNF mRNA]; Scopolamine inhibits the reaction [Pilocarpine results in increased expression of BDNF mRNA]
Scopolamine results in decreased expression of BDNF mRNA; Scopolamine results in decreased expression of BDNF protein
[acanthoside B co-treated with Scopolamine] results in increased expression of BDNF protein; [Tacrine co-treated with Scopolamine] results in increased expression of BDNF protein; Ashwagandha inhibits the reaction [Scopolamine results in decreased expression of BDNF mRNA]; Ashwagandha inhibits the reaction [Scopolamine results in decreased expression of BDNF protein]; dihydroactinidiolide inhibits the reaction [Scopolamine results in decreased expression of BDNF mRNA]; Donepezil inhibits the reaction [Scopolamine results in decreased expression of BDNF mRNA]; Melatonin inhibits the reaction [Scopolamine results in decreased expression of BDNF protein]; Plant Extracts inhibits the reaction [Scopolamine results in decreased expression of BDNF mRNA]; Serotonin analog inhibits the reaction [Scopolamine results in decreased expression of BDNF protein]; Tacrine inhibits the reaction [Scopolamine results in decreased expression of BDNF protein]
CTD PMID:8405262 PMID:8635431 PMID:22096544 PMID:26408985 PMID:26434561 More... NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G Cacna1d calcium channel, voltage-dependent, L type, alpha 1D subunit increases expression ISO Scopolamine results in increased expression of CACNA1D mRNA CTD PMID:12818353 NCBI chr14:29,761,898...30,213,113
Ensembl chr14:29,761,896...30,213,412
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2, beta decreases expression ISO Scopolamine results in decreased expression of CAMKK2 mRNA CTD PMID:17540011 NCBI chr 5:122,856,064...122,918,295
Ensembl chr 5:122,869,233...122,917,472
JBrowse link
G Cartpt CART prepropeptide decreases expression ISO Scopolamine results in decreased expression of CARTPT mRNA CTD PMID:17540011 NCBI chr13:100,034,991...100,037,191
Ensembl chr13:100,034,997...100,037,599
JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
increases cleavage
increases activity
EXP
ISO
Scopolamine results in increased expression of CASP3 mRNA; Scopolamine results in increased expression of CASP3 protein
Galantamine inhibits the reaction [Scopolamine results in increased cleavage of CASP3 protein]; intybin inhibits the reaction [Scopolamine results in increased cleavage of CASP3 protein]
Scopolamine results in increased activity of CASP3 protein
dihydroactinidiolide inhibits the reaction [Scopolamine results in increased activity of CASP3 protein]; Donepezil inhibits the reaction [Scopolamine results in increased activity of CASP3 protein]; Plant Extracts inhibits the reaction [Scopolamine results in increased expression of CASP3 mRNA]
CTD PMID:17120751 PMID:26434561 PMID:27346436 PMID:34371027 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Cat catalase multiple interactions
decreases activity
increases activity
EXP
ISO
acanthoside B inhibits the reaction [Scopolamine results in decreased activity of CAT protein]; chong-myung-tang inhibits the reaction [Scopolamine results in decreased activity of CAT protein]; dihydroactinidiolide inhibits the reaction [Scopolamine results in decreased activity of CAT protein]; Donepezil inhibits the reaction [Scopolamine results in decreased activity of CAT protein]; Piracetam inhibits the reaction [Scopolamine results in increased activity of CAT protein]; Plant Extracts inhibits the reaction [Scopolamine results in increased activity of CAT protein]; Tacrine inhibits the reaction [Scopolamine results in decreased activity of CAT protein]
Galantamine inhibits the reaction [Scopolamine results in decreased activity of CAT protein]; intybin inhibits the reaction [Scopolamine results in decreased activity of CAT protein]
CTD PMID:20673844 PMID:27346436 PMID:27717698 PMID:31077737 PMID:34371027 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cd3e CD3 antigen, epsilon polypeptide decreases expression ISO Scopolamine results in decreased expression of CD3E mRNA CTD PMID:17540011 NCBI chr 9:44,910,033...44,920,961
Ensembl chr 9:44,910,038...44,920,925
JBrowse link
G Cdkl4 cyclin dependent kinase like 4 increases expression ISO Scopolamine results in increased expression of CDKL4 mRNA CTD PMID:17540011 NCBI chr17:80,830,979...80,885,242
Ensembl chr17:80,830,979...80,885,242
JBrowse link
G Chat choline O-acetyltransferase decreases activity
multiple interactions
ISO
EXP
Scopolamine results in decreased activity of CHAT protein
protopanaxadiol inhibits the reaction [Scopolamine results in decreased activity of CHAT protein]; Serotonin analog inhibits the reaction [Scopolamine results in decreased activity of CHAT protein]
kangshuai yizhi inhibits the reaction [Scopolamine results in decreased activity of CHAT protein]
CTD PMID:20694781 PMID:26408985 PMID:29133030 NCBI chr14:32,130,160...32,187,866
Ensembl chr14:32,130,160...32,187,946
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1, CNS multiple interactions
decreases expression
increases expression
ISO
EXP
[[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; Canagliflozin affects the reaction [Scopolamine results in decreased expression of CHRM1 protein]
Scopolamine results in increased expression of CHRM1 mRNA
7-fluoro-1,3-diphenylisoquinoline-1-amine inhibits the reaction [Scopolamine results in decreased expression of CHRM1 protein]; Plant Extracts inhibits the reaction [Scopolamine results in increased expression of CHRM1 mRNA]
CTD PMID:11553362 PMID:26434561 PMID:28837785 PMID:32001261 NCBI chr19:8,641,369...8,660,970
Ensembl chr19:8,641,153...8,660,951
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 increases response to substance EXP CHRM4 protein results in increased susceptibility to Scopolamine CTD PMID:12729838 NCBI chr 2:91,752,531...91,760,180
Ensembl chr 2:91,757,594...91,759,033
JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 decreases response to substance EXP CHRM5 protein results in decreased susceptibility to Scopolamine CTD PMID:13679217 NCBI chr 2:112,306,055...112,365,487
Ensembl chr 2:112,309,516...112,311,114
JBrowse link
G Chrna4 cholinergic receptor, nicotinic, alpha polypeptide 4 affects binding
multiple interactions
ISO Scopolamine binds to [CHRNA4 protein binds to CHRNB2 protein]
Scopolamine promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]
CTD PMID:15733544 NCBI chr 2:180,664,104...180,685,339
Ensembl chr 2:180,660,173...180,685,339
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit affects binding
multiple interactions
ISO Scopolamine binds to [CHRNA4 protein binds to CHRNB2 protein]
Scopolamine promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]
CTD PMID:15733544 NCBI chr 3:89,660,755...89,671,939
Ensembl chr 3:89,653,502...89,671,939
JBrowse link
G Coch cochlin decreases expression ISO Scopolamine results in decreased expression of COCH mRNA CTD PMID:12818353 NCBI chr12:51,640,156...51,652,558
Ensembl chr12:51,640,124...51,652,554
JBrowse link
G Coro1b coronin, actin binding protein 1B increases expression ISO Scopolamine results in increased expression of CORO1B mRNA CTD PMID:12818353 NCBI chr19:4,198,610...4,204,034
Ensembl chr19:4,198,618...4,204,034
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B increases expression ISO Scopolamine results in increased expression of COX5B mRNA CTD PMID:12818353 NCBI chr 1:36,730,568...36,732,469
Ensembl chr 1:36,730,530...36,732,762
JBrowse link
G Creb1 cAMP responsive element binding protein 1 decreases phosphorylation
multiple interactions
EXP Scopolamine results in decreased phosphorylation of CREB1 protein
acanthoside B inhibits the reaction [Scopolamine results in decreased phosphorylation of CREB1 protein]; Serotonin analog inhibits the reaction [Scopolamine results in decreased phosphorylation of CREB1 protein]; Tacrine inhibits the reaction [Scopolamine results in decreased phosphorylation of CREB1 protein]
CTD PMID:26408985 PMID:31077737 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Cryab crystallin, alpha B increases expression ISO Scopolamine results in increased expression of CRYAB mRNA CTD PMID:17540011 NCBI chr 9:50,657,251...50,667,936
Ensembl chr 9:50,662,625...50,667,936
JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) multiple interactions
decreases response to substance
EXP IL1RN protein inhibits the reaction [CSF2 protein results in decreased susceptibility to Scopolamine] CTD PMID:8877002 NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493
JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 decreases expression ISO Scopolamine results in decreased expression of CXCR5 mRNA CTD PMID:12818353 NCBI chr 9:44,423,084...44,437,741
Ensembl chr 9:44,423,084...44,473,174
JBrowse link
G Ddc dopa decarboxylase decreases expression ISO Scopolamine results in decreased expression of DDC mRNA CTD PMID:17540011 NCBI chr11:11,764,101...11,848,144
Ensembl chr11:11,764,101...11,848,144
JBrowse link
G Dguok deoxyguanosine kinase increases expression ISO Scopolamine results in increased expression of DGUOK mRNA CTD PMID:17540011 NCBI chr 6:83,457,199...83,483,887
Ensembl chr 6:83,457,199...83,483,951
JBrowse link
G Dio2 deiodinase, iodothyronine, type II increases expression ISO Scopolamine results in increased expression of DIO2 mRNA CTD PMID:12818353 NCBI chr12:90,691,326...90,705,812
Ensembl chr12:90,691,326...90,705,812
JBrowse link
G Dusp5 dual specificity phosphatase 5 decreases expression ISO Scopolamine results in decreased expression of DUSP5 mRNA CTD PMID:17540011 NCBI chr19:53,517,576...53,530,240
Ensembl chr19:53,517,540...53,530,862
JBrowse link
G Dusp6 dual specificity phosphatase 6 decreases expression ISO Scopolamine results in decreased expression of DUSP6 mRNA CTD PMID:17540011 NCBI chr10:99,098,676...99,103,351
Ensembl chr10:99,099,093...99,103,351
JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO Scopolamine results in decreased expression of EGFR mRNA CTD PMID:12818353 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Egr1 early growth response 1 multiple interactions
decreases expression
ISO
EXP
[Scopolamine co-treated with 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine] results in increased expression of EGR1 mRNA; Scopolamine affects the reaction [SK&F 82958 results in increased expression of EGR1 mRNA]
Donepezil inhibits the reaction [Scopolamine results in decreased expression of EGR1 protein]; protopanaxadiol inhibits the reaction [Scopolamine results in decreased expression of EGR1 protein]
Scopolamine results in decreased expression of EGR1 mRNA
CTD PMID:8861055 PMID:17540011 PMID:29133030 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Egr2 early growth response 2 decreases expression ISO Scopolamine results in decreased expression of EGR2 mRNA CTD PMID:17540011 NCBI chr10:67,370,334...67,383,354
Ensembl chr10:67,371,305...67,378,018
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha increases expression ISO Scopolamine results in increased expression of EIF2S1 mRNA CTD PMID:12818353 NCBI chr12:78,908,846...78,933,784
Ensembl chr12:78,908,593...78,933,784
JBrowse link
G Eml1 echinoderm microtubule associated protein like 1 decreases expression ISO Scopolamine results in decreased expression of EML1 mRNA CTD PMID:17540011 NCBI chr12:108,337,265...108,505,835
Ensembl chr12:108,337,216...108,505,876
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions
decreases expression
increases expression
ISO
EXP
[Scopolamine co-treated with 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine] results in increased expression of FOS mRNA; Physostigmine inhibits the reaction [Scopolamine promotes the reaction [SK&F 82958 results in increased expression of FOS mRNA]]; Ro4368554 inhibits the reaction [Scopolamine results in increased expression of FOS protein]; Scopolamine affects the reaction [SK&F 82958 results in increased expression of FOS mRNA]; Scopolamine inhibits the reaction [Haloperidol results in increased expression of FOS protein]; Scopolamine promotes the reaction [SK&F 82958 results in increased expression of FOS mRNA]
Scopolamine results in decreased expression of FOS protein
Donepezil inhibits the reaction [Scopolamine results in decreased expression of FOS protein]; protopanaxadiol inhibits the reaction [Scopolamine results in decreased expression of FOS protein]
Scopolamine results in decreased expression of FOS mRNA
CTD PMID:1393566 PMID:8281324 PMID:8861055 PMID:11337201 PMID:17540011 More... NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 increases expression ISO Scopolamine results in increased expression of GABBR1 mRNA CTD PMID:17540011 NCBI chr17:37,356,888...37,385,197
Ensembl chr17:37,356,858...37,385,959
JBrowse link
G Gap43 growth associated protein 43 multiple interactions
decreases expression
ISO Ashwagandha inhibits the reaction [Scopolamine results in decreased expression of GAP43 protein]; withanone inhibits the reaction [Scopolamine results in decreased expression of GAP43 protein] CTD PMID:22096544 NCBI chr16:42,068,915...42,161,014
Ensembl chr16:42,068,805...42,161,014
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression
multiple interactions
EXP Scopolamine results in decreased expression of GFAP mRNA; Scopolamine results in decreased expression of GFAP protein
Ashwagandha inhibits the reaction [Scopolamine results in decreased expression of GFAP mRNA]; Ashwagandha inhibits the reaction [Scopolamine results in decreased expression of GFAP protein]; withanone inhibits the reaction [Scopolamine results in decreased expression of GFAP protein]
CTD PMID:22096544 NCBI chr11:102,778,162...102,791,368
Ensembl chr11:102,778,162...102,791,738
JBrowse link
G Gjb2 gap junction protein, beta 2 increases expression ISO Scopolamine results in increased expression of GJB2 mRNA CTD PMID:17540011 NCBI chr14:57,336,059...57,342,159
Ensembl chr14:57,336,057...57,342,159
JBrowse link
G Gpc3 glypican 3 decreases expression ISO Scopolamine results in decreased expression of GPC3 mRNA CTD PMID:12818353 NCBI chr  X:51,361,303...51,702,851
Ensembl chr  X:51,361,303...51,702,827
JBrowse link
G Grm4 glutamate receptor, metabotropic 4 multiple interactions ISO Scopolamine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium] CTD PMID:18171729 NCBI chr17:27,641,361...27,732,800
Ensembl chr17:27,641,361...27,740,377
JBrowse link
G Gsr glutathione reductase decreases activity
multiple interactions
EXP Scopolamine results in decreased activity of GSR protein
Serotonin analog inhibits the reaction [Scopolamine results in decreased activity of GSR protein]; Tacrine inhibits the reaction [Scopolamine results in decreased activity of GSR protein]
CTD PMID:26408985 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
JBrowse link
G Gypc glycophorin C decreases expression ISO Scopolamine results in decreased expression of GYPC mRNA CTD PMID:17540011 NCBI chr18:32,661,373...32,693,087
Ensembl chr18:32,661,375...32,693,087
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
EXP 7-fluoro-1,3-diphenylisoquinoline-1-amine inhibits the reaction [Scopolamine results in increased expression of HMOX1 protein] CTD PMID:32001261 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Homer1 homer scaffolding protein 1 decreases expression ISO Scopolamine results in decreased expression of HOMER1 mRNA CTD PMID:17540011 NCBI chr13:93,440,265...93,549,471
Ensembl chr13:93,436,143...93,541,637
JBrowse link
G Hrh1 histamine receptor H1 multiple interactions ISO [Histamine binds to and results in increased activity of HRH1 protein] which results in decreased susceptibility to Scopolamine; Pyrilamine inhibits the reaction [[Histamine binds to and results in increased activity of HRH1 protein] which results in decreased susceptibility to Scopolamine] CTD PMID:19215234 NCBI chr 6:114,374,897...114,459,432
Ensembl chr 6:114,374,897...114,460,257
JBrowse link
G Hrh2 histamine receptor H2 multiple interactions ISO [[thioperamide results in increased abundance of Histamine] which results in increased activity of HRH2 protein] which results in decreased susceptibility to Scopolamine; Cimetidine inhibits the reaction [[Histamine binds to and results in increased activity of HRH2 protein] which results in decreased susceptibility to Scopolamine] CTD PMID:11640976 PMID:19215234 NCBI chr13:54,345,990...54,390,201
Ensembl chr13:54,346,148...54,390,199
JBrowse link
G Hrh3 histamine receptor H3 multiple interactions ISO [clobenpropit binds to and results in decreased activity of HRH3 protein] which results in decreased susceptibility to Scopolamine CTD PMID:16488453 NCBI chr 2:179,741,258...179,746,264
Ensembl chr 2:179,741,258...179,746,281
JBrowse link
G Hspa2 heat shock protein 2 increases expression ISO Scopolamine results in increased expression of HSPA2 mRNA CTD PMID:12818353 NCBI chr12:76,450,688...76,453,712
Ensembl chr12:76,450,950...76,453,712
JBrowse link
G Htr1a 5-hydroxytryptamine (serotonin) receptor 1A multiple interactions
increases expression
ISO [4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine binds to and results in increased activity of HTR1A] which results in decreased susceptibility to Scopolamine; N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [[4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine binds to and results in increased activity of HTR1A] which results in decreased susceptibility to Scopolamine]
Scopolamine increases expression of Htr1a mRNA in amygdala, hippocampal formation; Scopolamine increases expression of Htr1a protein in amygdala, hippocampal formation
CTD
RGD
PMID:10578133 PMID:27760517 RGD:405850209 NCBI chr13:105,580,040...105,584,630
Ensembl chr13:105,580,147...105,584,630
JBrowse link
G Htr2c 5-hydroxytryptamine (serotonin) receptor 2C increases expression ISO Scopolamine results in increased expression of HTR2C mRNA CTD PMID:17540011 NCBI chr  X:145,745,509...145,980,273
Ensembl chr  X:145,745,509...145,980,273
JBrowse link
G Htr6 5-hydroxytryptamine (serotonin) receptor 6 decreases expression ISO Scopolamine results in decreased expression of HTR6 mRNA CTD PMID:19733250 NCBI chr 4:138,787,017...138,802,881
Ensembl chr 4:138,788,419...138,802,881
JBrowse link
G Ifng interferon gamma multiple interactions
increases expression
ISO Fatty Acids, Unsaturated deficiency promotes the reaction [Scopolamine results in increased expression of IFNG mRNA] CTD PMID:21161262 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Il10 interleukin 10 multiple interactions
decreases expression
EXP acanthoside B inhibits the reaction [Scopolamine results in decreased expression of IL10 protein]; polygalacic acid inhibits the reaction [Scopolamine results in decreased expression of IL10 protein]; Tacrine inhibits the reaction [Scopolamine results in decreased expression of IL10 protein] CTD PMID:26926176 PMID:31077737 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il1a interleukin 1 alpha decreases response to substance EXP IL1A protein results in decreased susceptibility to Scopolamine CTD PMID:8003924 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
EXP
ISO
Scopolamine results in increased expression of IL1B mRNA; Scopolamine results in increased expression of IL1B protein
Fatty Acids, Unsaturated deficiency promotes the reaction [Scopolamine results in increased expression of IL1B mRNA]
acanthoside B inhibits the reaction [Scopolamine results in increased expression of IL1B protein]; polygalacic acid inhibits the reaction [Scopolamine results in increased expression of IL1B protein]; Tacrine inhibits the reaction [Scopolamine results in increased expression of IL1B protein]; timosaponin AIII inhibits the reaction [Scopolamine results in increased expression of IL1B protein]
CTD PMID:18357464 PMID:19426756 PMID:21161262 PMID:26926176 PMID:31077737 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions EXP IL1RN protein inhibits the reaction [CSF2 protein results in decreased susceptibility to Scopolamine] CTD PMID:8877002 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO
EXP
Fatty Acids, Unsaturated deficiency promotes the reaction [Scopolamine results in increased expression of IL6 mRNA]; Scopolamine promotes the reaction [Fatty Acids, Unsaturated deficiency results in increased expression of IL6 mRNA]
acanthoside B inhibits the reaction [Scopolamine results in increased expression of IL6 protein]; Tacrine inhibits the reaction [Scopolamine results in increased expression of IL6 protein]
Scopolamine results in increased expression of IL6 mRNA; Scopolamine results in increased expression of IL6 protein
CTD PMID:18357464 PMID:21161262 PMID:31077737 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor 1 increases expression ISO Scopolamine results in increased expression of ITPR1 mRNA CTD PMID:12818353 NCBI chr 6:108,190,044...108,528,077
Ensembl chr 6:108,190,057...108,528,070
JBrowse link
G Jun jun proto-oncogene multiple interactions
decreases expression
ISO
EXP
Physostigmine inhibits the reaction [Scopolamine promotes the reaction [SK&F 82958 results in increased expression of JUN mRNA]]; Scopolamine promotes the reaction [SK&F 82958 results in increased expression of JUN mRNA]
Donepezil inhibits the reaction [Scopolamine results in decreased expression of JUN protein]; protopanaxadiol inhibits the reaction [Scopolamine results in decreased expression of JUN protein]
CTD PMID:11337201 PMID:29133030 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Junb jun B proto-oncogene decreases expression ISO Scopolamine results in decreased expression of JUNB mRNA CTD PMID:17540011 NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347
JBrowse link
G Kcna4 potassium voltage-gated channel, shaker-related subfamily, member 4 increases expression ISO Scopolamine results in increased expression of KCNA4 mRNA CTD PMID:12579815 NCBI chr 2:107,120,934...107,157,149
Ensembl chr 2:107,120,984...107,128,847
JBrowse link
G Kcnb1 potassium voltage gated channel, Shab-related subfamily, member 1 increases expression ISO Scopolamine results in increased expression of KCNB1 mRNA CTD PMID:12579815 PMID:15567561 NCBI chr 2:166,937,889...167,032,088
Ensembl chr 2:166,937,889...167,032,075
JBrowse link
G Kcnd2 potassium voltage-gated channel, Shal-related family, member 2 decreases expression ISO Scopolamine results in decreased expression of KCND2 mRNA CTD PMID:12579815 NCBI chr 6:21,212,101...21,729,804
Ensembl chr 6:21,215,502...21,729,804
JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 multiple interactions ISO Scopolamine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium] CTD PMID:18171729 NCBI chr 2:55,301,814...55,488,157
Ensembl chr 2:55,325,982...55,488,157
JBrowse link
G Klf2 Kruppel-like transcription factor 2 (lung) decreases expression ISO Scopolamine results in decreased expression of KLF2 mRNA CTD PMID:17540011 NCBI chr 8:73,072,906...73,075,498
Ensembl chr 8:73,072,877...73,075,500
JBrowse link
G Klf4 Kruppel-like transcription factor 4 (gut) decreases expression ISO Scopolamine results in decreased expression of KLF4 mRNA CTD PMID:17540011 NCBI chr 4:55,527,137...55,536,984
Ensembl chr 4:55,527,143...55,532,466
JBrowse link
G Lnpep leucyl/cystinyl aminopeptidase multiple interactions ISO [AGT protein modified form binds to and results in decreased activity of LNPEP protein] which results in decreased susceptibility to Scopolamine CTD PMID:11707427 NCBI chr17:17,747,985...17,846,303
Ensembl chr17:17,741,672...17,845,312
JBrowse link
G Madd MAP-kinase activating death domain increases expression ISO Scopolamine results in increased expression of MADD mRNA CTD PMID:12818353 NCBI chr 2:90,967,705...91,013,404
Ensembl chr 2:90,967,705...91,014,182
JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions
decreases expression
ISO Ashwagandha inhibits the reaction [Scopolamine results in decreased expression of MAP2 protein]; withanone inhibits the reaction [Scopolamine results in decreased expression of MAP2 protein] CTD PMID:22096544 NCBI chr 1:66,214,337...66,481,742
Ensembl chr 1:66,214,432...66,481,742
JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO Scopolamine results in decreased expression of MAPT mRNA CTD PMID:12818353 NCBI chr11:104,120,235...104,222,916
Ensembl chr11:104,122,216...104,222,916
JBrowse link
G Mbp myelin basic protein multiple interactions
decreases expression
EXP Melatonin inhibits the reaction [Scopolamine results in decreased expression of MBP protein] CTD PMID:29476728 NCBI chr18:82,492,883...82,603,762
Ensembl chr18:82,493,271...82,603,762
JBrowse link
G Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric decreases expression EXP
ISO
Scopolamine results in decreased expression of MUC5AC protein CTD PMID:18357464 PMID:21161262 NCBI chr 7:141,342,695...141,372,964
Ensembl chr 7:141,342,709...141,372,968
JBrowse link
G Nefh neurofilament, heavy polypeptide decreases expression
multiple interactions
ISO Scopolamine results in decreased expression of NEFH protein
Ashwagandha inhibits the reaction [Scopolamine results in decreased expression of NEFH protein]; withanone inhibits the reaction [Scopolamine results in decreased expression of NEFH protein]
CTD PMID:22096544 NCBI chr11:4,888,754...4,898,064
Ensembl chr11:4,888,754...4,898,064
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions
decreases expression
EXP
ISO
7-fluoro-1,3-diphenylisoquinoline-1-amine inhibits the reaction [Scopolamine results in decreased expression of NFE2L2 protein]
Galantamine inhibits the reaction [Scopolamine results in decreased expression of NFE2L2 protein]; intybin inhibits the reaction [Scopolamine results in decreased expression of NFE2L2 protein]
CTD PMID:27346436 PMID:32001261 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Ngf nerve growth factor decreases response to substance
decreases secretion
multiple interactions
increases response to substance
ISO
EXP
NGF protein results in decreased susceptibility to Scopolamine
Scopolamine results in decreased secretion of NGF protein
Galantamine promotes the reaction [Scopolamine results in decreased secretion of NGF protein]; intybin inhibits the reaction [Scopolamine results in decreased secretion of NGF protein]; Scopolamine inhibits the reaction [Pilocarpine results in increased expression of NGF mRNA]
NGF protein results in increased susceptibility to Scopolamine
CTD PMID:1661212 PMID:8635431 PMID:16405025 PMID:27346436 NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions
increases expression
EXP acanthoside B inhibits the reaction [Scopolamine results in increased expression of NOS2 protein]; Serotonin analog inhibits the reaction [Scopolamine results in increased expression of NOS2 protein]; Tacrine inhibits the reaction [Scopolamine results in increased expression of NOS2 protein] CTD PMID:26408985 PMID:31077737 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nova1 NOVA alternative splicing regulator 1 multiple interactions ISO Scopolamine inhibits the reaction [Pilocarpine results in increased expression of NOVA1 mRNA] CTD PMID:20470870 NCBI chr12:46,744,678...46,866,143
Ensembl chr12:46,741,300...46,865,712
JBrowse link
G Nova2 NOVA alternative splicing regulator 2 multiple interactions ISO Scopolamine inhibits the reaction [Pilocarpine results in decreased expression of NOVA2 mRNA] CTD PMID:20470870 NCBI chr 7:18,659,319...18,699,244
Ensembl chr 7:18,659,813...18,699,244
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions
decreases expression
EXP Serotonin analog inhibits the reaction [Scopolamine results in decreased expression of NQO1 protein] CTD PMID:26408985 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide quinone reductase 2 increases expression ISO Scopolamine results in increased expression of NQO2 mRNA CTD PMID:20861374 NCBI chr13:34,148,642...34,172,448
Ensembl chr13:34,148,670...34,172,426
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 decreases expression ISO Scopolamine results in decreased expression of NR1D1 mRNA CTD PMID:17540011 NCBI chr11:98,658,758...98,666,233
Ensembl chr11:98,658,758...98,666,159
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 decreases expression ISO Scopolamine results in decreased expression of NR4A1 mRNA CTD PMID:17540011 NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676
JBrowse link
G Ntf3 neurotrophin 3 multiple interactions ISO Scopolamine inhibits the reaction [Pilocarpine results in decreased expression of NTF3 mRNA] CTD PMID:8635431 NCBI chr 6:126,078,375...126,143,703
Ensembl chr 6:126,078,375...126,143,873
JBrowse link
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 multiple interactions
decreases expression
ISO
EXP
Scopolamine inhibits the reaction [Pilocarpine results in increased expression of NTRK2 mRNA]
Scopolamine results in decreased expression of NTRK2 protein
[acanthoside B co-treated with Scopolamine] results in increased phosphorylation of NTRK2 protein; [Tacrine co-treated with Scopolamine] results in increased phosphorylation of NTRK2 protein; Melatonin inhibits the reaction [Scopolamine results in decreased expression of NTRK2 protein]
CTD PMID:8635431 PMID:29476728 PMID:31077737 NCBI chr13:58,954,363...59,281,782
Ensembl chr13:58,954,383...59,281,784
JBrowse link
G Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 multiple interactions ISO Scopolamine inhibits the reaction [Pilocarpine results in increased expression of NTRK3 mRNA] CTD PMID:8635431 NCBI chr 7:77,825,711...78,228,865
Ensembl chr 7:77,825,707...78,387,760
JBrowse link
G Pdcd4 programmed cell death 4 increases expression ISO Scopolamine results in increased expression of PDCD4 mRNA CTD PMID:12818353 NCBI chr19:53,880,662...53,926,024
Ensembl chr19:53,880,662...53,918,291
JBrowse link
G Pdyn prodynorphin decreases response to substance
multiple interactions
increases expression
EXP
ISO
PDYN protein modified form results in decreased susceptibility to Scopolamine
MR 2266 inhibits the reaction [PDYN protein modified form results in decreased susceptibility to Scopolamine]
Scopolamine results in increased expression of PDYN mRNA
CTD PMID:7768285 PMID:17540011 NCBI chr 2:129,528,469...129,541,858
Ensembl chr 2:129,528,485...129,541,764
JBrowse link
G Penk preproenkephalin multiple interactions ISO Scopolamine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA] CTD PMID:7637876 NCBI chr 4:4,133,536...4,138,815
Ensembl chr 4:4,133,531...4,138,819
JBrowse link
G Pgam1 phosphoglycerate mutase 1 decreases expression ISO Scopolamine results in decreased expression of PGAM1 mRNA CTD PMID:12818353 NCBI chr19:41,900,310...41,907,104
Ensembl chr19:41,900,362...41,907,099
JBrowse link
G Prep prolyl endopeptidase increases response to substance
increases expression
multiple interactions
ISO PREP protein results in increased susceptibility to Scopolamine
Scopolamine results in increased expression of PREP protein
Piracetam inhibits the reaction [Scopolamine results in increased expression of PREP protein]
CTD PMID:17244263 PMID:18318186 NCBI chr10:44,943,312...45,038,847
Ensembl chr10:44,943,299...45,043,294
JBrowse link
G Prkra protein kinase, interferon inducible double stranded RNA dependent activator decreases expression ISO Scopolamine results in decreased expression of PRKRA mRNA CTD PMID:12818353 NCBI chr 2:76,436,385...76,478,614
Ensembl chr 2:76,460,242...76,478,359
JBrowse link
G Psen2 presenilin 2 decreases expression ISO Scopolamine results in decreased expression of PSEN2 mRNA CTD PMID:12818353 NCBI chr 1:180,054,569...180,091,030
Ensembl chr 1:180,054,569...180,091,003
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions
EXP Scopolamine results in increased expression of PTGS2 protein
acanthoside B inhibits the reaction [Scopolamine results in increased expression of PTGS2 protein]; Serotonin analog inhibits the reaction [Scopolamine results in increased expression of PTGS2 protein]; Tacrine inhibits the reaction [Scopolamine results in increased expression of PTGS2 protein]
CTD PMID:26408985 PMID:31077737 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rab14 RAB14, member RAS oncogene family increases expression ISO Scopolamine results in increased expression of RAB14 mRNA CTD PMID:17540011 NCBI chr 2:35,070,217...35,091,132
Ensembl chr 2:35,070,217...35,091,132
JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor (GEF) 3 decreases expression ISO Scopolamine results in decreased expression of RAPGEF3 mRNA CTD PMID:12818353 NCBI chr15:97,637,886...97,666,300
Ensembl chr15:97,642,651...97,665,853
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP mangiferin inhibits the reaction [Scopolamine results in increased phosphorylation of and results in increased activity of RELA protein]; Scopolamine results in increased phosphorylation of and results in increased activity of RELA protein; timosaponin AIII inhibits the reaction [Scopolamine results in increased phosphorylation of and results in increased activity of RELA protein] CTD PMID:19182383 PMID:19426756 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Rem2 rad and gem related GTP binding protein 2 decreases expression ISO Scopolamine results in decreased expression of REM2 mRNA CTD PMID:17540011 NCBI chr14:54,713,676...54,717,889
Ensembl chr14:54,713,557...54,717,888
JBrowse link
G Rgs7bp regulator of G-protein signalling 7 binding protein decreases expression ISO Scopolamine results in decreased expression of RGS7BP mRNA CTD PMID:17540011 NCBI chr13:105,082,412...105,191,438
Ensembl chr13:105,082,412...105,191,438
JBrowse link
G Robo3 roundabout guidance receptor 3 decreases expression ISO Scopolamine results in decreased expression of ROBO3 mRNA CTD PMID:17540011 NCBI chr 9:37,327,341...37,344,730
Ensembl chr 9:37,326,965...37,344,542
JBrowse link
G Rraga Ras-related GTP binding A increases expression ISO Scopolamine results in increased expression of RRAGA mRNA CTD PMID:12818353 NCBI chr 4:86,493,910...86,495,522
Ensembl chr 4:86,493,905...86,495,522
JBrowse link
G S100a4 S100 calcium binding protein A4 decreases expression ISO Scopolamine results in decreased expression of S100A4 mRNA CTD PMID:17540011 NCBI chr 3:90,511,077...90,513,349
Ensembl chr 3:90,511,078...90,513,352
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 increases expression ISO Scopolamine results in increased expression of S1PR1 mRNA CTD PMID:12818353 NCBI chr 3:115,504,082...115,508,704
Ensembl chr 3:115,504,082...115,508,721
JBrowse link
G Scamp2 secretory carrier membrane protein 2 increases expression ISO Scopolamine results in increased expression of SCAMP2 mRNA CTD PMID:12818353 NCBI chr 9:57,468,227...57,496,081
Ensembl chr 9:57,468,226...57,496,078
JBrowse link
G Sigmar1 sigma non-opioid intracellular receptor 1 multiple interactions EXP [2-(4-morpholino)ethyl-1-phenylcyclohexane-1-carboxylate binds to and results in increased activity of SIGMAR1 protein] which results in decreased susceptibility to Scopolamine; [igmesine binds to and results in increased activity of SIGMAR1 protein] which results in decreased susceptibility to Scopolamine CTD PMID:12028363 NCBI chr 4:41,738,493...41,741,359
Ensembl chr 4:41,738,493...41,756,157
JBrowse link
G Slc47a1 solute carrier family 47, member 1 multiple interactions ISO Scopolamine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr11:61,234,226...61,269,668
Ensembl chr11:61,234,227...61,269,171
JBrowse link
G Slc47a2 solute carrier family 47, member 2 multiple interactions ISO Scopolamine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr11:61,192,453...61,233,686
Ensembl chr11:61,192,457...61,233,686
JBrowse link
G Syp synaptophysin multiple interactions
decreases expression
increases expression
ISO
EXP
cyclo-L-glycyl-L-2-allylproline inhibits the reaction [Scopolamine results in increased expression of SYP protein]
dihydroactinidiolide inhibits the reaction [Scopolamine results in decreased expression of SYP mRNA]; Donepezil inhibits the reaction [Scopolamine results in decreased expression of SYP mRNA]
CTD PMID:20188767 PMID:34371027 NCBI chr  X:7,504,819...7,519,495
Ensembl chr  X:7,504,710...7,519,495
JBrowse link
G Tac1 tachykinin 1 decreases response to substance ISO TAC1 protein modified form results in decreased susceptibility to Scopolamine CTD PMID:20600432 NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP
ISO
acanthoside B inhibits the reaction [Scopolamine results in increased expression of TNF protein]; mangiferin inhibits the reaction [Scopolamine results in increased expression of TNF protein]; Tacrine inhibits the reaction [Scopolamine results in increased expression of TNF protein]; timosaponin AIII inhibits the reaction [Scopolamine results in increased expression of TNF protein]
Scopolamine results in increased expression of TNF mRNA
Scopolamine results in increased expression of TNF mRNA; Scopolamine results in increased expression of TNF protein
CTD PMID:18357464 PMID:19182383 PMID:19426756 PMID:21161262 PMID:31077737 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnrc6a trinucleotide repeat containing 6a decreases expression ISO Scopolamine results in decreased expression of TNRC6A mRNA CTD PMID:17540011 NCBI chr 7:122,630,324...122,794,519
Ensembl chr 7:122,723,108...122,794,519
JBrowse link
G Tpd52l1 tumor protein D52-like 1 increases expression ISO Scopolamine results in increased expression of TPD52L1 mRNA CTD PMID:17540011 NCBI chr10:31,208,369...31,321,989
Ensembl chr10:31,208,372...31,321,954
JBrowse link
G Vgf VGF nerve growth factor inducible decreases expression ISO Scopolamine results in decreased expression of VGF mRNA CTD PMID:17540011 NCBI chr 5:137,054,156...137,062,205
Ensembl chr 5:137,055,246...137,062,205
JBrowse link
G Vip vasoactive intestinal polypeptide decreases response to substance ISO VIP protein results in decreased susceptibility to Scopolamine CTD PMID:8208360 NCBI chr10:5,589,131...5,597,617
Ensembl chr10:5,589,218...5,597,617
JBrowse link
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP-binding cassette, sub-family B member 11 multiple interactions
decreases activity
ISO Atropine inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Atropine results in decreased activity of ABCB11 protein
CTD PMID:24014644 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958
JBrowse link
G Abl1 c-abl oncogene 1, non-receptor tyrosine kinase multiple interactions ISO [Parathion co-treated with Atropine] results in increased expression of ABL1 mRNA CTD PMID:17390078 NCBI chr 2:31,578,256...31,697,105
Ensembl chr 2:31,578,388...31,694,239
JBrowse link
G Ache acetylcholinesterase multiple interactions ISO
EXP
Atropine inhibits the reaction [[Organophosphorus Compounds results in decreased activity of ACHE protein] which results in increased abundance of Acetylcholine]; Atropine inhibits the reaction [Carbachol results in increased metabolism of and results in increased secretion of ACHE protein]; Atropine inhibits the reaction [Paraoxon results in increased expression of ACHE protein]
[Atropine co-treated with Obidoxime Chloride] inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]; [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of ACHE protein; [Paraoxon co-treated with pralidoxime co-treated with Atropine] results in decreased activity of ACHE protein; [pralidoxime co-treated with Atropine] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; [tariquidar co-treated with asoxime chloride co-treated with Atropine] inhibits the reaction [Soman results in decreased activity of ACHE protein]; Atropine inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [[Paraoxon co-treated with pralidoxime co-treated with Atropine] results in decreased activity of ACHE protein]; pralidoxime promotes the reaction [[Atropine co-treated with Curcumin] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]]
[1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [[1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with cucurbit(7)uril] co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Atropine inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Atropine promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; Atropine promotes the reaction [haloxon results in increased phosphorylation of ACHE protein]; Atropine promotes the reaction [Paraoxon results in increased phosphorylation of ACHE protein]
CTD PMID:2241428 PMID:10421444 PMID:17963125 PMID:20105433 PMID:21600273 More... NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Adcy5 adenylate cyclase 5 increases response to substance EXP ADCY5 protein results in increased susceptibility to Atropine CTD PMID:12869393 NCBI chr16:34,974,933...35,126,108
Ensembl chr16:34,975,247...35,126,108
JBrowse link
G Aqp5 aquaporin 5 multiple interactions EXP Atropine inhibits the reaction [Pilocarpine affects the localization of AQP5 protein] CTD PMID:26208470 NCBI chr15:99,488,909...99,492,710
Ensembl chr15:99,488,663...99,492,710
JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the expression of BAX mRNA] CTD PMID:21971501 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcar1 breast cancer anti-estrogen resistance 1 multiple interactions ISO Atropine inhibits the reaction [[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of BCAR1 protein]] CTD PMID:10537051 NCBI chr 8:112,437,106...112,470,481
Ensembl chr 8:112,437,106...112,470,441
JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO [Atropine co-treated with pralidoxime] results in decreased expression of BCHE protein; [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of BCHE protein
[BCHE protein co-treated with asoxime chloride co-treated with pro-diazepam co-treated with Atropine] results in decreased susceptibility to VX-agent
CTD PMID:17963125 PMID:22981459 NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748
JBrowse link
G Bdkrb2 bradykinin receptor, beta 2 multiple interactions EXP BDKRB2 affects the susceptibility to [Propranolol co-treated with Atropine] CTD PMID:10614985 NCBI chr12:105,529,431...105,561,503
Ensembl chr12:105,529,485...105,561,496
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO Atropine inhibits the reaction [Carbon Tetrachloride results in increased expression of BMP6 mRNA] CTD PMID:18472332 NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278
JBrowse link
G Cacna1e calcium channel, voltage-dependent, R type, alpha 1E subunit multiple interactions ISO Atropine inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]] CTD PMID:12663092 NCBI chr 1:154,266,552...154,760,374
Ensembl chr 1:154,266,477...154,760,247
JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha affects activity ISO Atropine affects the activity of CALCA protein CTD PMID:7906887 PMID:10075105 NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592
JBrowse link
G Casp3 caspase 3 increases expression ISO Atropine results in increased expression of CASP3 mRNA CTD PMID:19815060 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CCL5 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CCL5 protein] CTD PMID:22245128 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Ccna1 cyclin A1 multiple interactions
increases expression
ISO [Parathion co-treated with Atropine] results in increased expression of CCNA1 mRNA
Atropine results in increased expression of CCNA1 mRNA
CTD PMID:17390078 NCBI chr 3:54,952,890...54,965,055
Ensembl chr 3:54,952,890...54,962,922
JBrowse link
G Ccnd3 cyclin D3 multiple interactions ISO [Parathion co-treated with Atropine] results in increased expression of CCND3 mRNA CTD PMID:17390078 NCBI chr17:47,815,976...47,910,614
Ensembl chr17:47,815,976...47,910,616
JBrowse link
G Ccne1 cyclin E1 multiple interactions
increases expression
ISO [Parathion co-treated with Atropine] results in increased expression of CCNE1 mRNA
Atropine results in increased expression of CCNE1 mRNA
CTD PMID:17390078 NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959
JBrowse link
G Ccne2 cyclin E2 increases expression
multiple interactions
ISO Atropine results in increased expression of CCNE2 mRNA
[Parathion co-treated with Atropine] results in increased expression of CCNE2 mRNA
CTD PMID:17390078 NCBI chr 4:11,190,489...11,204,781
Ensembl chr 4:11,191,351...11,204,779
JBrowse link
G Cd40 CD40 antigen multiple interactions ISO Atropine inhibits the reaction [Carbachol results in increased expression of CD40 protein] CTD PMID:16879495 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868
JBrowse link
G Cdc20 cell division cycle 20 increases expression
multiple interactions
ISO Atropine results in increased expression of CDC20 mRNA
[Parathion co-treated with Atropine] results in increased expression of CDC20 mRNA
CTD PMID:17390078 NCBI chr 4:118,290,098...118,294,540
Ensembl chr 4:118,290,098...118,294,549
JBrowse link
G Cdc6 cell division cycle 6 multiple interactions ISO [Parathion co-treated with Atropine] results in increased expression of CDC6 mRNA CTD PMID:17390078 NCBI chr11:98,798,627...98,814,768
Ensembl chr11:98,798,627...98,814,766
JBrowse link
G Cdk1 cyclin dependent kinase 1 increases expression
multiple interactions
ISO Atropine results in increased expression of CDK1 mRNA
[Parathion co-treated with Atropine] results in increased expression of CDK1 mRNA
CTD PMID:17390078 NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768
JBrowse link
G Ces1d carboxylesterase 1D multiple interactions ISO Atropine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate] CTD PMID:9311626 NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1, CNS multiple interactions
decreases activity
EXP
ISO
Atropine binds to and results in decreased activity of CHRM1 protein; Atropine inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]
Atropine results in decreased activity of CHRM1 protein
Atropine affects the reaction [muscarinic toxin 7 binds to CHRM1 protein]
CTD PMID:16439611 PMID:18316702 PMID:31830555 NCBI chr19:8,641,369...8,660,970
Ensembl chr19:8,641,153...8,660,951
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2, cardiac multiple interactions ISO Atropine binds to and results in decreased activity of CHRM2 protein CTD PMID:15140916 NCBI chr 6:36,364,928...36,505,573
Ensembl chr 6:36,365,019...36,505,349
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3, cardiac multiple interactions
decreases activity
ISO Atropine binds to and results in decreased activity of CHRM3 protein; Atropine inhibits the reaction [Carbachol results in increased activity of CHRM3 protein]
Atropine results in decreased activity of CHRM3 protein
CTD PMID:15140916 PMID:20708676 PMID:31830555 NCBI chr13:9,925,522...10,411,131
Ensembl chr13:9,925,522...10,410,883
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 affects binding
multiple interactions
ISO Atropine binds to CHRM4 protein
[WIN 62577 co-treated with Quinuclidinyl Benzilate] inhibits the reaction [Atropine binds to CHRM4 protein]
CTD PMID:16709648 NCBI chr 2:91,752,531...91,760,180
Ensembl chr 2:91,757,594...91,759,033
JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 multiple interactions ISO Atropine inhibits the reaction [Acetylcholine results in increased activity of CHRM5 protein] CTD PMID:31323226 NCBI chr 2:112,306,055...112,365,487
Ensembl chr 2:112,309,516...112,311,114
JBrowse link
G Chrna4 cholinergic receptor, nicotinic, alpha polypeptide 4 multiple interactions
affects binding
ISO Atropine promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]
Atropine binds to [CHRNA4 protein binds to CHRNB2 protein]
Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNA4 mRNA]]; Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNA4 protein]]
CTD PMID:15733544 PMID:21791372 NCBI chr 2:180,664,104...180,685,339
Ensembl chr 2:180,660,173...180,685,339
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit affects binding
multiple interactions
ISO Atropine binds to [CHRNA4 protein binds to CHRNB2 protein]
Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNB2 mRNA]]; Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNB2 protein]]
Atropine promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]
CTD PMID:15733544 PMID:21791372 NCBI chr 3:89,660,755...89,671,939
Ensembl chr 3:89,653,502...89,671,939
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of CREB1 protein] CTD PMID:21971501 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Crh corticotropin releasing hormone multiple interactions ISO [Atropine co-treated with SR 140333 co-treated with SR 48968] results in decreased activity of CRH protein
Atropine inhibits the reaction [acephate results in increased expression of CRH mRNA]; Atropine inhibits the reaction [acephate results in increased secretion of CRH protein]; Atropine inhibits the reaction [methamidophos results in increased expression of CRH mRNA]; Atropine inhibits the reaction [methamidophos results in increased secretion of CRH protein]
CTD PMID:12039681 PMID:12906840 NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of CTNNB1 protein mutant form]; Atropine inhibits the reaction [Parathion results in increased expression of CTNNB1 protein] CTD PMID:17390078 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CXCL1 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CXCL1 protein] CTD PMID:22245128 NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459
JBrowse link
G Dvl2 dishevelled segment polarity protein 2 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of DVL2 protein] CTD PMID:17390078 NCBI chr11:69,891,418...69,900,935
Ensembl chr11:69,891,421...69,903,127
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO EDN1 protein results in decreased activity of [Atropine co-treated with Histamine] CTD PMID:12906840 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of EGFR protein] CTD PMID:17390078 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO Atropine inhibits the reaction [Pilocarpine results in increased expression of EGR1 mRNA] CTD PMID:7968354 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Egr2 early growth response 2 multiple interactions ISO Atropine inhibits the reaction [Pilocarpine results in increased expression of EGR2 mRNA] CTD PMID:7968354 NCBI chr10:67,370,334...67,383,354
Ensembl chr10:67,371,305...67,378,018
JBrowse link
G Ezr ezrin multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of EZR protein] CTD PMID:17390078 NCBI chr17:7,005,530...7,050,179
Ensembl chr17:7,005,440...7,050,183
JBrowse link
G F2 coagulation factor II multiple interactions EXP [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in decreased expression of F2 mRNA; [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in increased activity of F2 protein CTD PMID:30515700 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F2r coagulation factor II thrombin receptor multiple interactions EXP [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in increased expression of F2R protein CTD PMID:30515700 NCBI chr13:95,738,288...95,754,974
Ensembl chr13:95,738,311...95,754,995
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions
increases expression
ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased expression of FOS protein]; Atropine inhibits the reaction [Pilocarpine results in increased expression of FOS mRNA]
Atropine inhibits the reaction [Paraoxon results in increased expression of FOS mRNA]
Atropine results in increased expression of FOS protein
CTD PMID:7968354 PMID:8281324 PMID:21787676 PMID:21971501 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Ghrl ghrelin multiple interactions ISO Atropine inhibits the reaction [[Pentobarbital co-treated with L-pyroglutamyl-L-histidyl-3,3-dimethylprolinamide] results in increased expression of GHRL protein] CTD PMID:16959836 NCBI chr 6:113,693,080...113,696,872
Ensembl chr 6:113,693,080...113,696,841
JBrowse link
G Glra1 glycine receptor, alpha 1 subunit multiple interactions ISO Atropine binds to and results in decreased activity of GLRA1 protein CTD PMID:15081878 NCBI chr11:55,405,065...55,499,024
Ensembl chr11:55,405,064...55,499,024
JBrowse link
G Grm4 glutamate receptor, metabotropic 4 multiple interactions ISO Atropine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium] CTD PMID:18171729 NCBI chr17:27,641,361...27,732,800
Ensembl chr17:27,641,361...27,740,377
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of ICAM1 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of ICAM1 protein] CTD PMID:22245128 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of IL1B mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of IL1B protein] CTD PMID:22245128 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions EXP [Atropine co-treated with Ketamine] inhibits the reaction [Soman results in increased expression of IL6 mRNA]; [Atropine co-treated with Ketamine] inhibits the reaction [Soman results in increased expression of IL6 protein] CTD PMID:22245128 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Jun jun proto-oncogene multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of JUN protein] CTD PMID:21971501 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Junb jun B proto-oncogene multiple interactions ISO Atropine inhibits the reaction [Pilocarpine results in increased expression of JUNB mRNA] CTD PMID:7968354 NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347
JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 multiple interactions ISO Atropine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium] CTD PMID:18171729 NCBI chr 2:55,301,814...55,488,157
Ensembl chr 2:55,325,982...55,488,157
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of KIT protein] CTD PMID:17390078 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382
JBrowse link
G Ltf lactotransferrin multiple interactions ISO Atropine inhibits the reaction [methylcholine results in increased secretion of LTF protein] CTD PMID:11112886 NCBI chr 9:110,848,360...110,871,834
Ensembl chr 9:110,848,339...110,871,835
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK1 protein] CTD PMID:21971501 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK14 protein] CTD PMID:21971501 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK3 protein] CTD PMID:21971501 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein] CTD PMID:21971501 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 multiple interactions
increases expression
ISO [Parathion co-treated with Atropine] results in increased expression of MCM4 mRNA
Atropine results in increased expression of MCM4 mRNA
CTD PMID:17390078 NCBI chr16:15,441,761...15,455,264
Ensembl chr16:15,441,761...15,455,264
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression
multiple interactions
ISO Atropine results in increased expression of MCM6 mRNA
[Parathion co-treated with Atropine] results in increased expression of MCM6 mRNA
CTD PMID:17390078 NCBI chr 1:128,259,312...128,287,442
Ensembl chr 1:128,259,327...128,287,401
JBrowse link
G Nefh neurofilament, heavy polypeptide affects expression ISO Atropine affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr11:4,888,754...4,898,064
Ensembl chr11:4,888,754...4,898,064
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression ISO Atropine results in increased expression of NLRP3 mRNA CTD PMID:28138970 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions ISO Atropine inhibits the reaction [Indomethacin results in increased activity of NOS2 protein]; Atropine inhibits the reaction [Indomethacin results in increased expression of NOS2 mRNA] CTD PMID:15610444 PMID:16944022 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Notch4 notch 4 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of NOTCH4 protein] CTD PMID:17390078 NCBI chr17:34,783,257...34,807,517
Ensembl chr17:34,783,242...34,807,477
JBrowse link
G Nppa natriuretic peptide type A affects activity ISO Atropine affects the activity of NPPA protein modified form CTD PMID:1363893 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536
JBrowse link
G Oprl1 opioid receptor-like 1 multiple interactions ISO Atropine inhibits the reaction [PNOC protein binds to and results in increased activity of OPRL1 protein] CTD PMID:12007927 NCBI chr 2:181,356,585...181,362,778
Ensembl chr 2:181,356,809...181,362,778
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO Atropine inhibits the reaction [Malathion results in increased expression of PCNA]; Atropine inhibits the reaction [Parathion results in increased expression of PCNA] CTD PMID:12762645 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
JBrowse link
G Pnoc prepronociceptin multiple interactions ISO Atropine inhibits the reaction [PNOC protein binds to and results in increased activity of OPRL1 protein] CTD PMID:12007927 NCBI chr14:65,638,931...65,662,908
Ensembl chr14:65,638,122...65,662,921
JBrowse link
G Pomc pro-opiomelanocortin-alpha multiple interactions ISO Atropine inhibits the reaction [Acetylcholine results in increased expression of POMC protein] CTD PMID:7588217 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP [Atropine co-treated with Glucose] binds to PPARA protein; Atropine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]] CTD PMID:18812576 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Atropine affects the reaction [Indomethacin results in increased expression of PTGS2]; Atropine inhibits the reaction [Indomethacin results in increased expression of PTGS2 mRNA]; Atropine inhibits the reaction [Indomethacin results in increased expression of PTGS2]; Atropine inhibits the reaction [SC 560 results in increased expression of PTGS2 mRNA] CTD PMID:15104355 PMID:15610444 PMID:16259740 PMID:16804302 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 multiple interactions ISO Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein]]; Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[wortmannin co-treated with oxophenylarsine] results in increased phosphorylation of PTK2 protein]]; Atropine inhibits the reaction [oxotremorine M promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with wortmannin] results in increased phosphorylation of PTK2 protein]] CTD PMID:10537051 NCBI chr15:73,076,951...73,297,192
Ensembl chr15:73,076,951...73,295,129
JBrowse link
G Pxn paxillin multiple interactions ISO Atropine inhibits the reaction [[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of PXN protein]] CTD PMID:10537051 NCBI chr 5:115,630,035...115,694,046
Ensembl chr 5:115,644,735...115,694,046
JBrowse link
G Rac3 Rac family small GTPase 3 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of RAC3 protein] CTD PMID:17390078 NCBI chr11:120,612,294...120,614,795
Ensembl chr11:120,612,296...120,614,795
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of RELA protein] CTD PMID:21971501 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of RHOA protein] CTD PMID:17390078 NCBI chr 9:108,183,359...108,215,142
Ensembl chr 9:108,183,328...108,215,133
JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 multiple interactions ISO Atropine inhibits the reaction [SLC22A1 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Atropine inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:16263091 PMID:21641380 NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Atropine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Atropine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]; Atropine inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:16263091 PMID:21599003 PMID:23770354 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
G Slc22a3 solute carrier family 22 (organic cation transporter), member 3 multiple interactions
increases uptake
ISO Atropine inhibits the reaction [SLC22A3 protein results in increased transport of 1-Methyl-4-phenylpyridinium]
SLC22A3 protein results in increased uptake of Atropine
CTD PMID:16263091 NCBI chr17:12,638,859...12,726,591
Ensembl chr17:12,637,847...12,726,591
JBrowse link
G Slc22a4 solute carrier family 22 (organic cation transporter), member 4 multiple interactions ISO Atropine inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 NCBI chr11:53,873,941...53,920,866
Ensembl chr11:53,873,949...53,918,916
JBrowse link
G Slc47a1 solute carrier family 47, member 1 multiple interactions ISO Atropine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr11:61,234,226...61,269,668
Ensembl chr11:61,234,227...61,269,171
JBrowse link
G Slc47a2 solute carrier family 47, member 2 multiple interactions ISO Atropine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr11:61,192,453...61,233,686
Ensembl chr11:61,192,457...61,233,686
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Atropine results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 2:164,195,990...164,231,086
Ensembl chr 2:164,195,990...164,231,015
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of SOCS3 mRNA] CTD PMID:22245128 NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873
JBrowse link
G Spn sialophorin increases response to substance EXP SPN protein results in increased susceptibility to Atropine CTD PMID:18711009 NCBI chr 7:126,731,404...126,743,785
Ensembl chr 7:126,731,404...126,736,995
JBrowse link
G Tat tyrosine aminotransferase multiple interactions ISO [Atropine co-treated with Obidoxime Chloride co-treated with Diazepam] inhibits the reaction [Dichlorvos results in increased expression of TAT protein] CTD PMID:7761789 NCBI chr 8:110,712,710...110,726,436
Ensembl chr 8:110,717,069...110,726,435
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO Atropine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA] CTD PMID:18472332 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of TNF mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of TNF protein] CTD PMID:22245128 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Trio triple functional domain (PTPRF interacting) multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of TRIO protein] CTD PMID:17390078 NCBI chr15:27,730,735...28,025,954
Ensembl chr15:27,730,737...28,025,934
JBrowse link
G Trp53 transformation related protein 53 multiple interactions ISO Atropine inhibits the reaction [Malathion results in increased expression of TP53 protein]; Atropine inhibits the reaction [Parathion results in increased expression of TP53 protein] CTD PMID:12762645 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 decreases response to substance EXP TRPA1 gene mutant form results in decreased susceptibility to Atropine CTD PMID:29627347 NCBI chr 1:14,942,868...14,989,086
Ensembl chr 1:14,942,872...14,989,086
JBrowse link
G Tshb thyroid stimulating hormone, beta subunit multiple interactions ISO [pralidoxime co-treated with Atropine] inhibits the reaction [methamidophos results in decreased expression of TSHB protein] CTD PMID:15891268 NCBI chr 3:102,684,621...102,718,175
Ensembl chr 3:102,682,781...102,690,034
JBrowse link
G Tspo translocator protein multiple interactions ISO [Ketamine co-treated with Midazolam co-treated with Valproic Acid] inhibits the reaction [[Sarin co-treated with [Atropine co-treated with trimethylene-bis(4-hydroxyiminomethylpyridinium)]] results in increased expression of TSPO protein]; [Sarin co-treated with [Atropine co-treated with trimethylene-bis(4-hydroxyiminomethylpyridinium)]] results in increased expression of TSPO protein CTD PMID:33823148 NCBI chr15:83,447,774...83,458,404
Ensembl chr15:83,447,793...83,458,404
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of VCAM1 mRNA] CTD PMID:22245128 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
tryptophol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO tryptophol results in increased activity of NR1I2 protein CTD PMID:33002526 NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22412
    role 22396
      biological role 22395
        molecular messenger 19583
          hormone 19141
            plant hormone 8911
              auxin 1680
                3-(1H-indol-3-yl)propanoic acid 7
                4-chloroindole-3-acetic acid 0
                indole-3-acetic acid + 22
                indole-3-acetonitrile + 0
                indole-3-butyric acid + 6
                phenylacetic acid + 1416
                synthetic auxin + 364
                tryptophol + 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 22412
    role 22396
      biological role 22395
        pharmacological role 20021
          agonist 19552
            hormone 19141
              plant hormone 8911
                auxin 1680
                  3-(1H-indol-3-yl)propanoic acid 7
                  4-chloroindole-3-acetic acid 0
                  indole-3-acetic acid + 22
                  indole-3-acetonitrile + 0
                  indole-3-butyric acid + 6
                  phenylacetic acid + 1416
                  synthetic auxin + 364
                  tryptophol + 1
paths to the root