Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ansamycin
go back to main search page
Accession:CHEBI:22565 term browser browse the term
Definition:A class of macrocyclic lactams that consist of an aromatic (phenyl or naphthyl) or quinonoid (benzoquinone or naphthoquinone) moiety that is bridged by an aliphatic chain.
Synonyms:xref: Wikipedia:Ansamycin


show annotations for term's descendants           Sort by:
 
geldanamycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acap2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 increases expression ISO geldanamycin results in increased expression of ACAP2 mRNA CTD PMID:26705709 NCBI chr11:73,078,966...73,193,496
Ensembl chr11:73,078,982...73,191,132
JBrowse link
G Actr2 actin related protein 2 increases expression ISO geldanamycin results in increased expression of ACTR2 mRNA CTD PMID:26705709 NCBI chr14:104,338,486...104,375,840
Ensembl chr14:104,340,434...104,375,649
JBrowse link
G Aff3 AF4/FMR2 family, member 3 increases expression ISO geldanamycin results in increased expression of AFF3 mRNA CTD PMID:26705709 NCBI chr 9:44,837,979...45,291,964
Ensembl chr 9:44,839,960...45,292,047
JBrowse link
G Aff4 AF4/FMR2 family, member 4 increases expression ISO geldanamycin results in increased expression of AFF4 mRNA CTD PMID:26705709 NCBI chr10:38,692,167...38,773,021
Ensembl chr10:38,692,211...38,773,021
JBrowse link
G Agfg1 ArfGAP with FG repeats 1 increases expression ISO geldanamycin results in increased expression of AGFG1 mRNA CTD PMID:26705709 NCBI chr 9:88,607,508...88,663,486
Ensembl chr 9:88,607,508...88,662,224
JBrowse link
G Ahr aryl hydrocarbon receptor increases localization
decreases expression
increases degradation
multiple interactions
ISO geldanamycin results in increased localization of AHR protein
geldanamycin results in decreased expression of AHR protein
geldanamycin results in increased degradation of AHR protein; geldanamycin results in increased degradation of AHR protein mutant form
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [geldanamycin results in decreased expression of AHR protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [geldanamycin results in increased degradation of AHR protein]; geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CSK protein binds to AHR protein]]; geldanamycin results in increased localization of and results in increased degradation of AHR protein; lactacystin inhibits the reaction [geldanamycin results in increased degradation of AHR protein]
CTD PMID:9664232 PMID:12237327 PMID:12606767 PMID:16226227 PMID:20057149 PMID:27105554 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation
decreases expression
ISO [geldanamycin co-treated with Bortezomib] results in decreased expression of AKT1 protein; geldanamycin inhibits the reaction [Tretinoin results in increased phosphorylation of AKT1 protein]; geldanamycin results in decreased expression of and results in decreased phosphorylation of AKT1 protein
geldanamycin results in decreased phosphorylation of AKT1 protein
geldanamycin results in decreased expression of AKT1 protein
CTD PMID:15781649 PMID:17293044 PMID:19167484 PMID:24211270 PMID:24450340 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt3 AKT serine/threonine kinase 3 increases expression ISO geldanamycin results in increased expression of AKT3 mRNA CTD PMID:26705709 NCBI chr13:95,076,308...95,348,913
Ensembl chr13:95,081,390...95,348,913
JBrowse link
G Amotl1 angiomotin-like 1 increases expression ISO geldanamycin results in increased expression of AMOTL1 mRNA CTD PMID:26705709 NCBI chr 8:13,037,265...13,157,701
Ensembl chr 8:13,042,641...13,109,487
JBrowse link
G Angpt1 angiopoietin 1 increases expression ISO geldanamycin results in increased expression of ANGPT1 mRNA CTD PMID:26705709 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206
JBrowse link
G Angptl1 angiopoietin-like 1 decreases expression ISO geldanamycin results in decreased expression of ANGPTL1 mRNA CTD PMID:26705709 NCBI chr13:74,456,487...74,463,031
Ensembl chr13:74,410,010...74,474,681
JBrowse link
G Ankrd1 ankyrin repeat domain 1 increases expression ISO geldanamycin results in increased expression of ANKRD1 mRNA CTD PMID:26705709 NCBI chr 1:254,726,985...254,745,673
Ensembl chr 1:254,726,969...254,735,548
JBrowse link
G Ap5m1 adaptor related protein complex 5 subunit mu 1 increases expression ISO geldanamycin results in increased expression of AP5M1 mRNA CTD PMID:26705709 NCBI chr15:25,933,483...25,955,745
Ensembl chr15:25,933,483...25,955,745
JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 increases expression ISO geldanamycin results in increased expression of APPL2 mRNA CTD PMID:26705709 NCBI chr 7:26,256,179...26,306,128
Ensembl chr 7:26,256,459...26,306,126
JBrowse link
G Arfip1 ADP-ribosylation factor interacting protein 1 increases expression ISO geldanamycin results in increased expression of ARFIP1 mRNA CTD PMID:26705709 NCBI chr 2:183,503,250...183,582,798
Ensembl chr 2:183,504,330...183,582,553
JBrowse link
G Aspm assembly factor for spindle microtubules increases expression ISO geldanamycin results in increased expression of ASPM mRNA CTD PMID:26705709 NCBI chr13:56,546,021...56,591,793
Ensembl chr13:56,546,021...56,591,793
JBrowse link
G Atp11b ATPase phospholipid transporting 11B (putative) increases expression ISO geldanamycin results in increased expression of ATP11B mRNA CTD PMID:26705709 NCBI chr 2:122,337,757...122,445,090
Ensembl chr 2:122,368,265...122,444,878
JBrowse link
G Atp11c ATPase phospholipid transporting 11C increases expression ISO geldanamycin results in increased expression of ATP11C mRNA CTD PMID:26705709 NCBI chr  X:143,340,712...143,525,588
Ensembl chr  X:143,346,252...143,453,612
JBrowse link
G Atp13a3 ATPase 13A3 increases expression ISO geldanamycin results in increased expression of ATP13A3 mRNA CTD PMID:26705709 NCBI chr11:73,936,750...73,963,852
Ensembl chr11:73,936,750...73,963,852
JBrowse link
G Atp13a5 ATPase 13A5 increases expression ISO geldanamycin results in increased expression of ATP13A5 mRNA CTD PMID:26705709 NCBI chr11:74,984,538...75,124,249
Ensembl chr11:74,984,613...75,124,249
JBrowse link
G Atrx ATRX, chromatin remodeler increases expression ISO geldanamycin results in increased expression of ATRX mRNA CTD PMID:26705709 NCBI chr  X:76,820,110...76,979,155
Ensembl chr  X:76,692,970...76,708,878
Ensembl chr  X:76,692,970...76,708,878
JBrowse link
G Atxn7l3b ataxin 7-like 3B increases expression ISO geldanamycin results in increased expression of ATXN7L3B mRNA CTD PMID:26705709 NCBI chr 7:55,600,879...55,604,403
Ensembl chr 7:55,600,889...55,604,403
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO [geldanamycin co-treated with Bortezomib] results in decreased expression of BCL2 protein
geldanamycin results in decreased expression of BCL2 protein
CTD PMID:15781649 PMID:28673683 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases response to substance
multiple interactions
ISO BCL2L1 protein results in decreased susceptibility to geldanamycin
[geldanamycin co-treated with Bortezomib] results in decreased expression of BCL2L1 protein
CTD PMID:15781649 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcor BCL6 co-repressor increases expression ISO geldanamycin results in increased expression of BCOR mRNA CTD PMID:26705709 NCBI chr  X:11,570,155...11,692,022
Ensembl chr  X:11,648,989...11,691,099
JBrowse link
G Bdp1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB increases expression ISO geldanamycin results in increased expression of BDP1 mRNA CTD PMID:26705709 NCBI chr 2:30,248,458...30,340,211
Ensembl chr 2:30,250,633...30,340,208
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 multiple interactions ISO [geldanamycin co-treated with Bortezomib] results in decreased expression of BIRC2 protein CTD PMID:15781649 NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
JBrowse link
G Bod1l1 biorientation of chromosomes in cell division 1-like 1 increases expression ISO geldanamycin results in increased expression of BOD1L1 mRNA CTD PMID:26705709 NCBI chr14:73,738,137...73,792,935
Ensembl chr14:73,738,137...73,791,656
JBrowse link
G Cab39 calcium binding protein 39 increases expression ISO geldanamycin results in increased expression of CAB39 mRNA CTD PMID:26705709 NCBI chr 9:92,834,327...92,895,778
Ensembl chr 9:92,834,357...92,895,778
JBrowse link
G Cald1 caldesmon 1 increases expression ISO geldanamycin results in increased expression of CALD1 mRNA CTD PMID:26705709 NCBI chr 4:62,103,948...62,291,375
Ensembl chr 4:62,220,736...62,291,489
JBrowse link
G Cask calcium/calmodulin dependent serine protein kinase increases expression ISO geldanamycin results in increased expression of CASK mRNA CTD PMID:26705709 NCBI chr  X:9,815,652...10,156,155
Ensembl chr  X:9,815,652...10,156,155
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO Acetylcysteine inhibits the reaction [geldanamycin results in increased activity of CASP3 protein]; geldanamycin inhibits the reaction [Demecolcine results in increased activity of CASP3 protein]; geldanamycin inhibits the reaction [Nicotine results in increased activity of CASP3 protein] CTD PMID:12115584 PMID:12530016 PMID:14576064 PMID:24998639 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 multiple interactions
increases activity
ISO Acetylcysteine inhibits the reaction [geldanamycin results in increased activity of CASP7 protein] CTD PMID:24998639 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp9 caspase 9 multiple interactions ISO geldanamycin inhibits the reaction [Doxorubicin results in increased cleavage of CASP9 protein] CTD PMID:16311509 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cbl Cbl proto-oncogene increases expression ISO geldanamycin results in increased expression of CBL mRNA CTD PMID:26705709 NCBI chr 8:48,481,256...48,564,775
Ensembl chr 8:48,489,036...48,564,722
JBrowse link
G Ccdc186 coiled-coil domain containing 186 increases expression ISO geldanamycin results in increased expression of CCDC186 mRNA CTD PMID:26705709 NCBI chr 1:277,603,601...277,635,379
Ensembl chr 1:277,606,995...277,629,196
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
ISO [geldanamycin co-treated with Bortezomib] results in decreased expression of CCND1 protein
geldanamycin results in decreased expression of CCND1 mRNA; geldanamycin results in decreased expression of CCND1 protein
CTD PMID:15781649 PMID:17959518 PMID:24211270 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 increases expression ISO geldanamycin results in increased expression of CCND2 mRNA CTD PMID:26705709 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Ccne2 cyclin E2 increases expression ISO geldanamycin results in increased expression of CCNE2 mRNA CTD PMID:26705709 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Ccnk cyclin K increases expression ISO geldanamycin results in increased expression of CCNK mRNA CTD PMID:26705709 NCBI chr 6:132,090,235...132,113,560
Ensembl chr 6:132,090,218...132,113,557
JBrowse link
G Cdc27 cell division cycle 27 increases expression ISO geldanamycin results in increased expression of CDC27 mRNA CTD PMID:26705709 NCBI chr10:92,551,754...92,602,214
Ensembl chr10:92,554,081...92,602,082
JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone multiple interactions ISO geldanamycin inhibits the reaction [HSP90AA1 protein binds to SRC protein binds to CDC37 protein]; geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of CDC37 protein] CTD PMID:17223712 NCBI chr 8:22,160,922...22,173,797
Ensembl chr 8:22,154,067...22,173,804
JBrowse link
G Cdca2 cell division cycle associated 2 increases expression ISO geldanamycin results in increased expression of CDCA2 mRNA CTD PMID:26705709 NCBI chr15:44,365,396...44,411,601
Ensembl chr15:44,365,405...44,411,004
JBrowse link
G Cdh1 cadherin 1 multiple interactions
increases expression
ISO geldanamycin promotes the reaction [CDH1 protein binds to CTNNB1 protein]; IL24 protein promotes the reaction [geldanamycin promotes the reaction [CDH1 protein binds to CTNNB1 protein]]; IL24 protein promotes the reaction [geldanamycin results in increased expression of CDH1 protein] CTD PMID:17024233 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh4 cadherin 4 increases expression ISO geldanamycin results in increased expression of CDH4 mRNA CTD PMID:26705709 NCBI chr 3:175,220,520...175,283,144
Ensembl chr 3:175,144,495...175,279,761
JBrowse link
G Cdk13 cyclin-dependent kinase 13 increases expression ISO geldanamycin results in increased expression of CDK13 mRNA CTD PMID:26705709 NCBI chr17:49,833,194...49,922,932
Ensembl chr17:49,833,400...49,921,550
JBrowse link
G Cdk14 cyclin-dependent kinase 14 increases expression ISO geldanamycin results in increased expression of CDK14 mRNA CTD PMID:26705709 NCBI chr 4:25,825,567...26,419,443
Ensembl chr 4:25,825,567...26,419,127
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO geldanamycin results in decreased expression of CDK4 protein CTD PMID:28673683 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdk6 cyclin-dependent kinase 6 increases expression ISO geldanamycin results in increased expression of CDK6 mRNA CTD PMID:26705709 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions EXP geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [[CEBPB protein binds to CEBPB protein] which binds to PTGS2 promoter]] CTD PMID:11133817 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cenpj centromere protein J increases expression ISO geldanamycin results in increased expression of CENPJ mRNA CTD PMID:26705709 NCBI chr15:36,745,672...36,809,228
Ensembl chr15:36,746,088...36,798,814
JBrowse link
G Cep89 centrosomal protein 89 increases expression ISO geldanamycin results in increased expression of CEP89 mRNA CTD PMID:26705709 NCBI chr 1:91,663,723...91,705,979
Ensembl chr 1:91,663,736...91,706,094
JBrowse link
G Cep95 centrosomal protein 95 increases expression ISO geldanamycin results in increased expression of CEP95 mRNA CTD PMID:26705709 NCBI chr10:94,988,362...95,017,774
Ensembl chr10:94,988,362...95,016,344
JBrowse link
G Cers6 ceramide synthase 6 increases expression ISO geldanamycin results in increased expression of CERS6 mRNA CTD PMID:26705709 NCBI chr 3:55,094,240...55,338,370
Ensembl chr 3:55,094,637...55,338,445
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO geldanamycin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; geldanamycin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; geldanamycin promotes the reaction [miglustat results in increased activity of CFTR protein mutant form] CTD PMID:18230692 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex increases degradation ISO geldanamycin results in increased degradation of CHUK protein CTD PMID:15930313 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 increases expression ISO geldanamycin results in increased expression of CLIP1 mRNA CTD PMID:26705709 NCBI chr12:38,345,203...38,452,650
Ensembl chr12:38,345,456...38,452,652
JBrowse link
G Clk4 CDC-like kinase 4 increases expression ISO geldanamycin results in increased expression of CLK4 mRNA CTD PMID:26705709 NCBI chr10:36,715,565...36,733,473
Ensembl chr10:36,715,565...36,733,133
JBrowse link
G Col12a1 collagen type XII alpha 1 chain increases expression ISO geldanamycin results in increased expression of COL12A1 mRNA CTD PMID:26705709 NCBI chr 8:87,042,820...87,150,701
Ensembl chr 8:87,040,799...87,158,368
JBrowse link
G Col25a1 collagen type XXV alpha 1 chain increases expression ISO geldanamycin results in increased expression of COL25A1 mRNA CTD PMID:26705709 NCBI chr 2:235,515,364...235,705,448
Ensembl chr 2:235,596,123...235,715,057
JBrowse link
G Col8a1 collagen type VIII alpha 1 chain increases expression ISO geldanamycin results in increased expression of COL8A1 mRNA CTD PMID:26705709 NCBI chr11:44,877,690...45,006,203
Ensembl chr11:44,877,859...45,007,891
JBrowse link
G Cpne3 copine 3 increases expression ISO geldanamycin results in increased expression of CPNE3 mRNA CTD PMID:26705709 NCBI chr 5:33,525,307...33,574,610
Ensembl chr 5:33,528,154...33,574,596
JBrowse link
G Crcp CGRP receptor component increases expression ISO geldanamycin results in increased expression of CRCP mRNA CTD PMID:26705709 NCBI chr12:30,125,237...30,160,857
Ensembl chr12:30,125,168...30,180,115
JBrowse link
G Csk C-terminal Src kinase multiple interactions
decreases activity
ISO geldanamycin inhibits the reaction [CSK protein results in increased susceptibility to Tetrachlorodibenzodioxin]; geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CSK protein binds to AHR protein]]
geldanamycin results in decreased activity of CSK protein
CTD PMID:9664232 NCBI chr 8:62,405,714...62,424,707
Ensembl chr 8:62,405,715...62,424,303
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 increases expression ISO geldanamycin results in increased expression of CSNK2A1 mRNA CTD PMID:26705709 NCBI chr 3:147,713,808...147,760,375
Ensembl chr 3:147,713,821...147,757,862
JBrowse link
G Ctdspl2 CTD small phosphatase like 2 increases expression ISO geldanamycin results in increased expression of CTDSPL2 mRNA CTD PMID:26705709 NCBI chr 3:113,906,803...113,957,289
Ensembl chr 3:113,918,629...113,960,101
JBrowse link
G Ctnna1 catenin alpha 1 increases expression ISO geldanamycin results in increased expression of CTNNA1 mRNA CTD PMID:26705709 NCBI chr18:27,923,229...28,055,972
Ensembl chr18:27,923,572...28,055,960
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO geldanamycin promotes the reaction [CDH1 protein binds to CTNNB1 protein]; IL24 protein promotes the reaction [geldanamycin promotes the reaction [CDH1 protein binds to CTNNB1 protein]] CTD PMID:17024233 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cul5 cullin 5 increases expression ISO geldanamycin results in increased expression of CUL5 mRNA CTD PMID:26705709 NCBI chr 8:58,199,992...58,255,149
Ensembl chr 8:58,202,821...58,253,688
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 increases expression ISO geldanamycin results in increased expression of CYP17A1 mRNA CTD PMID:15711029 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]
geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
CTD PMID:12237327 PMID:20057149 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 increases expression ISO geldanamycin results in increased expression of DDR2 mRNA CTD PMID:26705709 NCBI chr13:88,311,639...88,436,561
Ensembl chr13:88,317,145...88,436,789
JBrowse link
G Ddx17 DEAD-box helicase 17 increases expression ISO geldanamycin results in increased expression of DDX17 mRNA CTD PMID:26705709 NCBI chr 7:120,761,843...120,765,012
Ensembl chr 7:120,761,826...120,780,641
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked increases expression ISO geldanamycin results in increased expression of DDX3X mRNA CTD PMID:26705709 NCBI chr  X:10,400,363...10,414,010
Ensembl chr  X:10,400,366...10,413,995
JBrowse link
G Ddx42 DEAD-box helicase 42 increases expression ISO geldanamycin results in increased expression of DDX42 mRNA CTD PMID:26705709 NCBI chr10:94,407,094...94,439,052
Ensembl chr10:94,407,559...94,439,052
JBrowse link
G Ddx6 DEAD-box helicase 6 increases expression ISO geldanamycin results in increased expression of DDX6 mRNA CTD PMID:26705709 NCBI chr 8:48,924,768...48,961,394
Ensembl chr 8:48,925,604...48,958,026
JBrowse link
G Dhx9 DExH-box helicase 9 increases expression ISO geldanamycin results in increased expression of DHX9 mRNA CTD PMID:26705709 NCBI chr13:70,885,503...70,922,278
Ensembl chr13:70,885,504...70,922,245
JBrowse link
G Dip2a disco-interacting protein 2 homolog A increases expression ISO geldanamycin results in increased expression of DIP2A mRNA CTD PMID:26705709 NCBI chr20:13,044,056...13,127,971
Ensembl chr20:13,044,104...13,127,487
JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 increases expression ISO geldanamycin results in increased expression of DLG1 mRNA CTD PMID:26705709 NCBI chr11:72,164,566...72,378,895
Ensembl chr11:72,163,749...72,378,895
JBrowse link
G Dmd dystrophin increases expression ISO geldanamycin results in increased expression of DMD mRNA CTD PMID:26705709 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259
JBrowse link
G Dnajc13 DnaJ heat shock protein family (Hsp40) member C13 increases expression ISO geldanamycin results in increased expression of DNAJC13 mRNA CTD PMID:26705709 NCBI chr 8:112,697,907...112,830,445
Ensembl chr 8:112,698,348...112,807,598
JBrowse link
G Dst dystonin increases expression ISO geldanamycin results in increased expression of DST mRNA CTD PMID:26705709 NCBI chr 9:37,902,336...38,296,961
Ensembl chr 9:37,902,303...38,196,273
JBrowse link
G E2f3 E2F transcription factor 3 increases expression ISO geldanamycin results in increased expression of E2F3 mRNA CTD PMID:26705709 NCBI chr17:36,334,136...36,408,831
Ensembl chr17:36,334,147...36,408,831
JBrowse link
G Edil3 EGF like repeats and discoidin domains 3 increases expression ISO geldanamycin results in increased expression of EDIL3 mRNA CTD PMID:26705709 NCBI chr 2:17,616,116...18,128,514
Ensembl chr 2:17,616,401...18,128,512
JBrowse link
G Edn1 endothelin 1 increases expression ISO geldanamycin results in increased expression of EDN1 mRNA CTD PMID:26705709 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Eea1 early endosome antigen 1 increases expression ISO geldanamycin results in increased expression of EEA1 mRNA CTD PMID:26705709 NCBI chr 7:37,101,415...37,186,534
Ensembl chr 7:37,018,459...37,186,732
JBrowse link
G Egf epidermal growth factor multiple interactions EXP
ISO
geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [EGF protein binds to EGFR protein]] CTD PMID:9605431 PMID:9664232 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
decreases expression
ISO
EXP
geldanamycin promotes the reaction [Sulfasalazine results in decreased expression of EGFR protein]
geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [EGF protein binds to EGFR protein]]
geldanamycin results in decreased expression of EGFR protein
CTD PMID:9605431 PMID:9664232 PMID:20007406 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Ehbp1 EH domain binding protein 1 increases expression ISO geldanamycin results in increased expression of EHBP1 mRNA CTD PMID:26705709 NCBI chr14:106,871,426...107,160,224
Ensembl chr14:106,871,430...107,160,334
JBrowse link
G Ehmt1 euchromatic histone lysine methyltransferase 1 increases expression ISO geldanamycin results in increased expression of EHMT1 mRNA CTD PMID:26705709 NCBI chr 3:1,966,974...2,123,858
Ensembl chr 3:1,960,957...2,123,820
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 increases expression ISO geldanamycin results in increased expression of ELL2 mRNA CTD PMID:26705709 NCBI chr 2:2,456,189...2,525,590
Ensembl chr 2:2,456,735...2,524,237
JBrowse link
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 increases expression ISO geldanamycin results in increased expression of EPB41L5 mRNA CTD PMID:26705709 NCBI chr13:35,622,472...35,673,449
Ensembl chr13:35,580,098...35,668,968
JBrowse link
G Eprs glutamyl-prolyl-tRNA synthetase increases expression ISO geldanamycin results in increased expression of EPRS1 mRNA CTD PMID:26705709 NCBI chr13:103,300,911...103,371,651
Ensembl chr13:103,300,932...103,371,577
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 increases degradation
multiple interactions
decreases expression
ISO geldanamycin results in increased degradation of ERBB2 protein
[geldanamycin binds to HSP90B1 protein] inhibits the reaction [HSP90B1 protein binds to ERBB2 protein]; geldanamycin inhibits the reaction [Quercetin promotes the reaction [ERBB2 protein binds to HSP90AA1 protein]]; geldanamycin results in decreased expression of and results in increased ubiquitination of ERBB2 protein; Quercetin promotes the reaction [geldanamycin results in decreased expression of and results in increased ubiquitination of ERBB2 protein]
geldanamycin results in decreased expression of ERBB2 protein
CTD PMID:8617772 PMID:11071886 PMID:17959518 PMID:18655187 PMID:24450340 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Ercc6l2 ERCC excision repair 6 like 2 increases expression ISO geldanamycin results in increased expression of ERCC6L2 mRNA CTD PMID:26705709 NCBI chr17:1,325,654...1,421,732
Ensembl chr17:1,305,016...1,421,685
JBrowse link
G Esco1 establishment of sister chromatid cohesion N-acetyltransferase 1 increases expression ISO geldanamycin results in increased expression of ESCO1 mRNA CTD PMID:26705709 NCBI chr18:1,789,796...1,857,271
Ensembl chr18:1,789,900...1,828,606
JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 increases expression ISO geldanamycin results in increased expression of ESCO2 mRNA CTD PMID:26705709 NCBI chr15:42,500,929...42,519,019
Ensembl chr15:42,500,929...42,518,855
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
decreases expression
decreases stability
increases degradation
ISO geldanamycin inhibits the reaction [Estradiol binds to ESR1 protein]; geldanamycin promotes the reaction [ESR1 protein binds to STUB1 protein]; STUB1 protein promotes the reaction [geldanamycin results in increased degradation of ESR1 protein]
geldanamycin results in decreased expression of ESR1 protein
geldanamycin results in decreased stability of ESR1 protein
CTD PMID:11448926 PMID:16037132 PMID:24211270 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor increases expression ISO geldanamycin results in increased expression of ETS1 mRNA CTD PMID:26705709 NCBI chr 8:33,756,634...33,879,625
Ensembl chr 8:33,816,386...33,879,625
JBrowse link
G Evi5 ecotropic viral integration site 5 increases expression ISO geldanamycin results in increased expression of EVI5 mRNA CTD PMID:26705709 NCBI chr14:2,892,738...3,038,237
Ensembl chr14:2,892,753...3,038,237
JBrowse link
G Fam126a family with sequence similarity 126, member A increases expression ISO geldanamycin results in increased expression of FAM126A mRNA CTD PMID:26705709 NCBI chr 4:7,661,710...7,770,179
Ensembl chr 4:7,661,558...7,770,232
JBrowse link
G Fam172a family with sequence similarity 172, member A increases expression ISO geldanamycin results in increased expression of FAM172A mRNA CTD PMID:26705709 NCBI chr 2:4,942,795...5,547,744
Ensembl chr 2:4,942,775...5,545,144
JBrowse link
G Fancb FA complementation group B increases expression ISO geldanamycin results in increased expression of FANCB mRNA CTD PMID:26705709 NCBI chr  X:31,124,018...31,140,790
Ensembl chr  X:31,124,018...31,140,711
JBrowse link
G Fancm FA complementation group M increases expression ISO geldanamycin results in increased expression of FANCM mRNA CTD PMID:26705709 NCBI chr 6:86,823,195...86,877,067
Ensembl chr 6:86,823,684...86,876,633
JBrowse link
G Fbn1 fibrillin 1 increases expression ISO geldanamycin results in increased expression of FBN1 mRNA CTD PMID:26705709 NCBI chr 3:117,569,708...117,766,160
Ensembl chr 3:117,569,697...117,766,120
JBrowse link
G Fgf7 fibroblast growth factor 7 multiple interactions ISO geldanamycin inhibits the reaction [ammonium trichloro(dioxoethylene-O,O'-)tellurate results in increased expression of FGF7 protein] CTD PMID:14656992 NCBI chr 3:118,315,859...118,368,464
Ensembl chr 3:118,317,761...118,366,872
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 increases expression ISO geldanamycin results in increased expression of FLT1 mRNA CTD PMID:26705709 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Fn1 fibronectin 1 increases expression ISO geldanamycin results in increased expression of FN1 mRNA CTD PMID:26705709 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fryl FRY like transcription coactivator increases expression ISO geldanamycin results in increased expression of FRYL mRNA CTD PMID:26705709 NCBI chr14:37,551,109...37,757,511
Ensembl chr14:37,551,940...37,756,149
JBrowse link
G G3bp1 G3BP stress granule assembly factor 1 increases expression ISO geldanamycin results in increased expression of G3BP1 mRNA CTD PMID:26705709 NCBI chr10:40,812,858...40,846,252
Ensembl chr10:40,812,858...40,846,252
JBrowse link
G Galnt5 polypeptide N-acetylgalactosaminyltransferase 5 increases expression ISO geldanamycin results in increased expression of GALNT5 mRNA CTD PMID:26705709 NCBI chr 3:44,025,964...44,072,073
Ensembl chr 3:44,025,300...44,074,678
JBrowse link
G Gls glutaminase increases expression ISO geldanamycin results in increased expression of GLS mRNA CTD PMID:26705709 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Gng12 G protein subunit gamma 12 increases expression ISO geldanamycin results in increased expression of GNG12 mRNA CTD PMID:26705709 NCBI chr 4:97,634,925...97,763,478
Ensembl chr 4:97,657,671...97,760,102
JBrowse link
G Golim4 golgi integral membrane protein 4 increases expression ISO geldanamycin results in increased expression of GOLIM4 mRNA CTD PMID:26705709 NCBI chr 2:174,321,303...174,413,847
Ensembl chr 2:174,322,673...174,413,236
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 increases expression ISO geldanamycin results in increased expression of GRIA3 mRNA CTD PMID:26705709 NCBI chr  X:127,561,843...127,829,763
Ensembl chr  X:127,562,660...127,829,753
JBrowse link
G Gtf2a1 general transcription factor 2A subunit 1 increases expression ISO geldanamycin results in increased expression of GTF2A1 mRNA CTD PMID:26705709 NCBI chr 6:115,321,110...115,352,659
Ensembl chr 6:115,320,467...115,352,681
JBrowse link
G H4f3 H1.3 linker histone, cluster member increases expression ISO geldanamycin results in increased expression of H1-3 mRNA CTD PMID:26705709 NCBI chr17:43,797,711...43,798,450
Ensembl chr17:43,797,721...43,798,383
JBrowse link
G Hacd2 3-hydroxyacyl-CoA dehydratase 2 increases expression ISO geldanamycin results in increased expression of HACD2 mRNA CTD PMID:26705709 NCBI chr11:68,893,684...68,985,635
Ensembl chr11:68,894,445...68,989,988
JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 increases expression ISO geldanamycin results in increased expression of HCN1 mRNA CTD PMID:26705709 NCBI chr 2:50,099,576...50,499,799
Ensembl chr 2:50,099,576...50,499,799
JBrowse link
G Heatr1 HEAT repeat containing 1 increases expression ISO geldanamycin results in increased expression of HEATR1 mRNA CTD PMID:26705709 NCBI chr17:66,446,135...66,488,303
Ensembl chr17:66,446,162...66,619,250
JBrowse link
G Hectd1 HECT domain E3 ubiquitin protein ligase 1 increases expression ISO geldanamycin results in increased expression of HECTD1 mRNA CTD PMID:26705709 NCBI chr 6:72,509,658...72,596,285
Ensembl chr 6:72,510,255...72,596,446
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
decreases expression
increases degradation
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [geldanamycin results in increased degradation of HIF1A protein]; geldanamycin inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]; lactacystin inhibits the reaction [geldanamycin results in increased degradation of HIF1A protein]
geldanamycin results in decreased expression of HIF1A protein
CTD PMID:11980636 PMID:12811834 PMID:14726529 PMID:15319539 PMID:16432534 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO geldanamycin inhibits the reaction [solanesol results in increased expression of HMOX1 mRNA]; geldanamycin inhibits the reaction [solanesol results in increased expression of HMOX1 protein] CTD PMID:25645596 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase multiple interactions ISO geldanamycin inhibits the reaction [Dexamethasone results in increased expression of and results in increased activity of HPGD protein] CTD PMID:15680906 NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
JBrowse link
G Hsf1 heat shock transcription factor 1 multiple interactions ISO geldanamycin inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; geldanamycin results in increased phosphorylation of and results in increased activity of HSF1 protein CTD PMID:10632574 PMID:25645596 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 affects binding
multiple interactions
EXP
ISO
geldanamycin binds to HSP90AA1 protein
geldanamycin inhibits the reaction [HSP90AA1 protein binds to SRC protein binds to CDC37 protein]; geldanamycin inhibits the reaction [KCNH2 protein binds to HSP90AA1 protein]; geldanamycin inhibits the reaction [Quercetin promotes the reaction [ERBB2 protein binds to HSP90AA1 protein]]
CTD PMID:12775586 PMID:17223712 PMID:18655187 PMID:21749116 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 affects binding
increases expression
EXP
ISO
geldanamycin binds to HSP90AB1 protein
geldanamycin results in increased expression of HSP90AB1 mRNA
CTD PMID:21749116 PMID:26705709 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 affects binding
multiple interactions
ISO geldanamycin binds to HSP90B1 protein
[geldanamycin binds to HSP90B1 protein] inhibits the reaction [HSP90B1 protein binds to ERBB2 protein]
CTD PMID:8617772 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression
multiple interactions
EXP
ISO
geldanamycin results in increased expression of HSPA1A mRNA; geldanamycin results in increased expression of HSPA1A protein
[geldanamycin results in increased expression of HSPA1A protein] which results in decreased susceptibility to Gentamicins
CTD PMID:11448926 PMID:19723345 PMID:25477506 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 increases expression
multiple interactions
ISO geldanamycin results in increased expression of HSPA4 mRNA; geldanamycin results in increased expression of HSPA4 protein
[geldanamycin results in increased expression of HSPA4 protein] which results in decreased susceptibility to Doxorubicin
CTD PMID:16311509 PMID:26705709 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression
affects expression
ISO Bortezomib promotes the reaction [geldanamycin results in increased expression of HSPA5 protein]; geldanamycin promotes the reaction [Bortezomib results in increased expression of HSPA5 protein]
geldanamycin affects the expression of HSPA5 protein
CTD PMID:14576064 PMID:15141013 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression ISO geldanamycin results in increased expression of HSPD1 mRNA CTD PMID:26705709 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Htt huntingtin multiple interactions ISO geldanamycin inhibits the reaction [HTT protein binds to HTT protein] CTD PMID:11406612 NCBI chr14:81,105,139...81,254,637
Ensembl chr14:81,105,139...81,254,637
JBrowse link
G Ice2 interactor of little elongation complex ELL subunit 2 increases expression ISO geldanamycin results in increased expression of ICE2 mRNA CTD PMID:26705709 NCBI chr 8:75,625,147...75,666,959
Ensembl chr 8:75,625,174...75,666,866
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
geldanamycin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL1B mRNA]
geldanamycin inhibits the reaction [IL1B protein results in decreased expression of VLDLR protein]
CTD PMID:12571865 PMID:15808840 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il24 interleukin 24 multiple interactions ISO IL24 protein promotes the reaction [geldanamycin promotes the reaction [CDH1 protein binds to CTNNB1 protein]]; IL24 protein promotes the reaction [geldanamycin results in increased expression of CDH1 protein] CTD PMID:17024233 NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
JBrowse link
G Il6 interleukin 6 multiple interactions ISO geldanamycin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA] CTD PMID:12571865 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6st interleukin 6 signal transducer increases expression ISO geldanamycin results in increased expression of IL6ST mRNA CTD PMID:26705709 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Inhba inhibin subunit beta A increases expression ISO geldanamycin results in increased expression of INHBA mRNA CTD PMID:26705709 NCBI chr17:51,894,869...51,919,998
Ensembl chr17:51,898,217...51,912,496
JBrowse link
G Inpp5a inositol polyphosphate-5-phosphatase A increases expression ISO geldanamycin results in increased expression of INPP5A mRNA CTD PMID:26705709 NCBI chr 1:211,732,163...211,920,844
Ensembl chr 1:211,732,713...211,921,099
JBrowse link
G Ipo8 importin 8 increases expression ISO geldanamycin results in increased expression of IPO8 mRNA CTD PMID:26705709 NCBI chr 4:183,228,688...183,295,253 JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 increases expression ISO geldanamycin results in increased expression of IQGAP1 mRNA CTD PMID:26705709 NCBI chr 1:142,525,041...142,615,673
Ensembl chr 1:142,525,046...142,615,673
JBrowse link
G Itga1 integrin subunit alpha 1 increases expression ISO geldanamycin results in increased expression of ITGA1 mRNA CTD PMID:26705709 NCBI chr 2:47,127,403...47,281,387
Ensembl chr 2:47,127,219...47,281,421
JBrowse link
G Itgb3 integrin subunit beta 3 increases expression ISO geldanamycin results in increased expression of ITGB3 mRNA CTD PMID:26705709 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Itprid2 ITPR interacting domain containing 2 increases expression ISO geldanamycin results in increased expression of ITPRID2 mRNA CTD PMID:26705709 NCBI chr 3:66,593,767...66,631,143
Ensembl chr 3:66,593,934...66,631,723
JBrowse link
G Jmjd1c jumonji domain containing 1C increases expression ISO geldanamycin results in increased expression of JMJD1C mRNA CTD PMID:26705709 NCBI chr20:22,751,743...22,914,080
Ensembl chr20:22,751,743...22,882,672
JBrowse link
G Kat6a lysine acetyltransferase 6A increases expression ISO geldanamycin results in increased expression of KAT6A mRNA CTD PMID:26705709 NCBI chr16:73,942,669...74,020,750
Ensembl chr16:73,943,455...74,023,005
JBrowse link
G Kbtbd2 kelch repeat and BTB domain containing 2 increases expression ISO geldanamycin results in increased expression of KBTBD2 mRNA CTD PMID:26705709 NCBI chr 4:87,088,759...87,111,576
Ensembl chr 4:87,088,759...87,111,025
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 affects localization
decreases activity
increases degradation
multiple interactions
decreases expression
ISO geldanamycin affects the localization of KCNH2 protein
geldanamycin results in decreased activity of KCNH2 protein
geldanamycin results in increased degradation of KCNH2 protein
geldanamycin inhibits the reaction [KCNH2 protein binds to HSP90AA1 protein]
geldanamycin results in decreased expression of KCNH2 protein modified form
CTD PMID:12775586 PMID:24052561 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Kdm6a lysine demethylase 6A increases expression ISO geldanamycin results in increased expression of KDM6A mRNA CTD PMID:26705709 NCBI chr  X:4,805,493...4,945,788
Ensembl chr  X:4,806,277...4,945,944
JBrowse link
G Kirrel1 kirre like nephrin family adhesion molecule 1 increases expression ISO geldanamycin results in increased expression of KIRREL1 mRNA CTD PMID:26705709 NCBI chr 2:186,420,743...186,515,209
Ensembl chr 2:186,420,795...186,515,135
JBrowse link
G Klf12 Kruppel-like factor 12 increases expression ISO geldanamycin results in increased expression of KLF12 mRNA CTD PMID:26705709 NCBI chr15:84,316,986...84,748,549
Ensembl chr15:84,324,470...84,748,525
JBrowse link
G Klhl24 kelch-like family member 24 increases expression ISO geldanamycin results in increased expression of KLHL24 mRNA CTD PMID:26705709 NCBI chr11:84,613,101...84,643,674
Ensembl chr11:84,615,760...84,633,504
JBrowse link
G Kmt2a lysine methyltransferase 2A increases expression ISO geldanamycin results in increased expression of KMT2A mRNA CTD PMID:26705709 NCBI chr 8:49,110,407...49,185,872
Ensembl chr 8:49,114,990...49,158,971
JBrowse link
G Lama4 laminin subunit alpha 4 increases expression ISO geldanamycin results in increased expression of LAMA4 mRNA CTD PMID:26705709 NCBI chr20:44,060,715...44,201,966
Ensembl chr20:44,060,731...44,209,614
JBrowse link
G Larp1b La ribonucleoprotein 1B increases expression ISO geldanamycin results in increased expression of LARP1B mRNA CTD PMID:26705709 NCBI chr 2:127,845,034...127,876,793
Ensembl chr 2:127,845,034...127,876,793
JBrowse link
G Larp4 La ribonucleoprotein 4 increases expression ISO geldanamycin results in increased expression of LARP4 mRNA CTD PMID:26705709 NCBI chr 7:141,630,229...141,676,242 JBrowse link
G Lars1 leucyl-tRNA synthetase 1 increases expression ISO geldanamycin results in increased expression of LARS1 mRNA CTD PMID:26705709 NCBI chr18:36,524,013...36,579,471
Ensembl chr18:36,524,007...36,579,403
JBrowse link
G Lima1 LIM domain and actin binding 1 increases expression ISO geldanamycin results in increased expression of LIMA1 mRNA CTD PMID:26705709 NCBI chr 7:141,428,113...141,528,447
Ensembl chr 7:141,428,063...141,528,397
JBrowse link
G Lin7a lin-7 homolog A, crumbs cell polarity complex component increases expression ISO geldanamycin results in increased expression of LIN7A mRNA CTD PMID:26705709 NCBI chr 7:49,429,613...49,627,835
Ensembl chr 7:49,385,705...49,656,856
JBrowse link
G Lman1 lectin, mannose-binding, 1 increases expression ISO geldanamycin results in increased expression of LMAN1 mRNA CTD PMID:26705709 NCBI chr18:61,683,377...61,707,344
Ensembl chr18:61,685,117...61,707,317
JBrowse link
G Lmo7 LIM domain 7 increases expression ISO geldanamycin results in increased expression of LMO7 mRNA CTD PMID:26705709 NCBI chr15:86,242,911...86,458,512
Ensembl chr15:86,243,148...86,457,739
JBrowse link
G LOC100911204 protein CASC5-like increases expression ISO geldanamycin results in increased expression of KNL1 mRNA CTD PMID:26705709 NCBI chr 3:112,531,429...112,560,698
Ensembl chr 3:112,531,703...112,560,634
JBrowse link
G LOC103690017 serine/threonine-protein kinase tousled-like 1 increases expression ISO geldanamycin results in increased expression of TLK1 mRNA CTD PMID:26705709 NCBI chr 3:57,318,512...57,411,623
Ensembl chr 3:57,318,795...57,389,901
JBrowse link
G Lpp LIM domain containing preferred translocation partner in lipoma increases expression ISO geldanamycin results in increased expression of LPP mRNA CTD PMID:26705709 NCBI chr11:79,192,603...79,827,858
Ensembl chr11:79,205,730...79,703,736
JBrowse link
G Lrrc58 leucine rich repeat containing 58 increases expression ISO geldanamycin results in increased expression of LRRC58 mRNA CTD PMID:26705709 NCBI chr11:65,747,235...65,759,558
Ensembl chr11:65,747,036...65,759,581
JBrowse link
G Lsm14b LSM family member 14B increases expression ISO geldanamycin results in increased expression of LSM14B mRNA CTD PMID:26705709 NCBI chr 3:175,408,433...175,419,180
Ensembl chr 3:175,408,629...175,417,610
JBrowse link
G Man1a2 mannosidase, alpha, class 1A, member 2 increases expression ISO geldanamycin results in increased expression of MAN1A2 mRNA CTD PMID:26705709 NCBI chr 2:202,891,537...203,043,847
Ensembl chr 2:202,891,537...203,043,847
JBrowse link
G Map1b microtubule-associated protein 1B increases expression ISO geldanamycin results in increased expression of MAP1B mRNA CTD PMID:26705709 NCBI chr 2:29,675,391...29,768,750
Ensembl chr 2:29,675,391...29,768,750
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions
decreases phosphorylation
ISO geldanamycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAP2K1 protein]
geldanamycin results in decreased phosphorylation of MAP2K1 protein
CTD PMID:8816498 PMID:19167484 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 decreases phosphorylation ISO geldanamycin results in decreased phosphorylation of MAP2K2 protein CTD PMID:19167484 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression ISO geldanamycin results in increased expression of MAP3K1 mRNA CTD PMID:26705709 NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 increases expression ISO geldanamycin results in increased expression of MAP3K5 mRNA CTD PMID:26705709 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Map4k5 mitogen-activated protein kinase kinase kinase kinase 5 increases expression ISO geldanamycin results in increased expression of MAP4K5 mRNA CTD PMID:26705709 NCBI chr 6:92,136,242...92,229,578
Ensembl chr 6:92,136,992...92,229,260
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases expression
decreases phosphorylation
ISO geldanamycin inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK1 protein]; geldanamycin inhibits the reaction [Endosulfan results in increased phosphorylation of MAPK1 protein]; geldanamycin inhibits the reaction [Heptachlor results in increased phosphorylation of MAPK1 protein]; geldanamycin inhibits the reaction [Hexachlorocyclohexane results in increased phosphorylation of MAPK1 protein]; geldanamycin inhibits the reaction [Tretinoin results in increased phosphorylation of MAPK1 protein]
geldanamycin results in decreased expression of MAPK1 mRNA
geldanamycin results in decreased phosphorylation of MAPK1 protein
geldanamycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]
CTD PMID:8816498 PMID:15888667 PMID:17293044 PMID:19167484 PMID:30166341 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation
ISO geldanamycin inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein]; geldanamycin inhibits the reaction [Endosulfan results in increased phosphorylation of MAPK3 protein]; geldanamycin inhibits the reaction [Heptachlor results in increased phosphorylation of MAPK3 protein]; geldanamycin inhibits the reaction [Hexachlorocyclohexane results in increased phosphorylation of MAPK3 protein]; geldanamycin inhibits the reaction [Tretinoin results in increased phosphorylation of MAPK3 protein]
geldanamycin results in decreased phosphorylation of MAPK3 protein
geldanamycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD PMID:8816498 PMID:15888667 PMID:17293044 PMID:19167484 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 increases expression ISO geldanamycin results in increased expression of MAPKAPK2 mRNA CTD PMID:26705709 NCBI chr13:47,785,157...47,871,684
Ensembl chr13:47,785,161...47,831,110
JBrowse link
G Matr3 matrin 3 increases expression ISO geldanamycin results in increased expression of MATR3 mRNA CTD PMID:26705709 NCBI chr18:28,351,691...28,390,764
Ensembl chr18:28,361,283...28,390,717
JBrowse link
G Mbnl1 muscleblind-like splicing regulator 1 increases expression ISO geldanamycin results in increased expression of MBNL1 mRNA CTD PMID:26705709 NCBI chr 2:150,698,248...150,867,791
Ensembl chr 2:150,756,185...150,869,690
JBrowse link
G Mbnl2 muscleblind-like splicing regulator 2 increases expression ISO geldanamycin results in increased expression of MBNL2 mRNA CTD PMID:26705709 NCBI chr15:105,640,097...105,797,933
Ensembl chr15:105,640,097...105,797,932
JBrowse link
G Mbtd1 mbt domain containing 1 increases expression ISO geldanamycin results in increased expression of MBTD1 mRNA CTD PMID:26705709 NCBI chr10:81,588,233...81,645,532
Ensembl chr10:81,592,114...81,642,663
JBrowse link
G Mcam melanoma cell adhesion molecule increases expression ISO geldanamycin results in increased expression of MCAM mRNA CTD PMID:26705709 NCBI chr 8:48,472,824...48,481,005
Ensembl chr 8:48,472,824...48,481,001
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 increases expression ISO geldanamycin results in increased expression of MCM4 mRNA CTD PMID:26705709 NCBI chr11:89,511,191...89,524,892
Ensembl chr11:89,511,191...89,524,892
JBrowse link
G Mdfic MyoD family inhibitor domain containing increases expression ISO geldanamycin results in increased expression of MDFIC mRNA CTD PMID:26705709 NCBI chr 4:42,202,546...42,282,499
Ensembl chr 4:42,202,838...42,282,496
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO geldanamycin results in increased expression of MDM2 mRNA CTD PMID:26705709 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Med13 mediator complex subunit 13 increases expression ISO geldanamycin results in increased expression of MED13 mRNA CTD PMID:26705709 NCBI chr10:73,702,327...73,787,084
Ensembl chr10:73,702,327...73,787,083
JBrowse link
G Med7 mediator complex subunit 7 increases expression ISO geldanamycin results in increased expression of MED7 mRNA CTD PMID:26705709 NCBI chr10:31,532,190...31,536,405
Ensembl chr10:31,532,250...31,536,405
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO geldanamycin results in increased expression of MET mRNA CTD PMID:26705709 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Mettl16 methyltransferase like 16 increases expression ISO geldanamycin results in increased expression of METTL16 mRNA CTD PMID:26705709 NCBI chr10:61,626,595...61,682,947
Ensembl chr10:61,626,597...61,672,136
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase multiple interactions ISO geldanamycin results in increased expression of and results in increased activity of MGMT protein CTD PMID:16950796 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Mier1 MIER1 transcriptional regulator increases expression ISO geldanamycin results in increased expression of MIER1 mRNA CTD PMID:26705709 NCBI chr 5:122,642,065...122,693,642
Ensembl chr 5:122,641,885...122,693,635
JBrowse link
G Mir21 microRNA 21 increases expression ISO geldanamycin results in increased expression of MIR21 mRNA CTD PMID:26705709 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mis18bp1 MIS18 binding protein 1 increases expression ISO geldanamycin results in increased expression of MIS18BP1 mRNA CTD PMID:26705709 NCBI chr 6:86,879,106...86,925,209
Ensembl chr 6:86,879,719...86,924,146
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions
decreases expression
ISO [geldanamycin co-treated with PTHLH protein modified form] results in increased expression of MMP1 mRNA
geldanamycin results in decreased expression of MMP1 mRNA
CTD PMID:12724357 PMID:26705709 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp16 matrix metallopeptidase 16 increases expression ISO geldanamycin results in increased expression of MMP16 mRNA CTD PMID:26705709 NCBI chr 5:31,568,344...31,818,368
Ensembl chr 5:31,568,419...31,810,484
JBrowse link
G Mt-nd6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 increases expression ISO geldanamycin results in increased expression of ND6 mRNA CTD PMID:26705709 NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
JBrowse link
G Myo5a myosin VA increases expression ISO geldanamycin results in increased expression of MYO5A mRNA CTD PMID:26705709 NCBI chr 8:82,038,966...82,156,507
Ensembl chr 8:82,037,977...82,156,617
JBrowse link
G Myocd myocardin increases expression ISO geldanamycin results in increased expression of MYOCD mRNA CTD PMID:26705709 NCBI chr10:51,682,053...51,781,458
Ensembl chr10:51,683,540...51,778,986
JBrowse link
G Mzt1 mitotic spindle organizing protein 1 increases expression ISO geldanamycin results in increased expression of MZT1 mRNA CTD PMID:26705709 NCBI chr15:83,429,437...83,442,118
Ensembl chr15:83,431,178...83,442,008
JBrowse link
G Nasp nuclear autoantigenic sperm protein increases expression ISO geldanamycin results in increased expression of NASP mRNA CTD PMID:26705709 NCBI chr 5:135,446,485...135,472,113
Ensembl chr 5:135,446,962...135,472,116
JBrowse link
G Nbas NBAS subunit of NRZ tethering complex increases expression ISO geldanamycin results in increased expression of NBAS mRNA CTD PMID:26705709 NCBI chr 6:38,474,773...38,777,146
Ensembl chr 6:38,474,804...38,777,806
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 increases expression ISO geldanamycin results in increased expression of NCOA2 mRNA CTD PMID:26705709 NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 increases expression ISO geldanamycin results in increased expression of NEDD9 mRNA CTD PMID:26705709 NCBI chr17:22,984,792...23,179,701
Ensembl chr17:22,984,844...23,179,701
JBrowse link
G Nes nestin increases expression ISO geldanamycin results in increased expression of NES mRNA CTD PMID:26705709 NCBI chr 2:187,343,109...187,352,972
Ensembl chr 2:187,344,056...187,352,969
JBrowse link
G Nf1 neurofibromin 1 increases expression ISO geldanamycin results in increased expression of NF1 mRNA CTD PMID:26705709 NCBI chr10:66,732,460...66,928,706
Ensembl chr10:66,690,133...66,928,903
JBrowse link
G Nf2 neurofibromin 2 increases expression ISO geldanamycin results in increased expression of NF2 mRNA CTD PMID:26705709 NCBI chr14:84,996,905...85,088,547
Ensembl chr14:84,996,905...85,088,523
JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 increases expression ISO geldanamycin results in increased expression of NFAT5 mRNA CTD PMID:26705709 NCBI chr19:38,446,059...38,533,735
Ensembl chr19:38,446,059...38,533,735
JBrowse link
G Nipbl NIPBL, cohesin loading factor increases expression ISO geldanamycin results in increased expression of NIPBL mRNA CTD PMID:26705709 NCBI chr 2:57,508,830...57,676,197
Ensembl chr 2:57,509,428...57,600,820
JBrowse link
G Nktr natural killer cell triggering receptor increases expression ISO geldanamycin results in increased expression of NKTR mRNA CTD PMID:26705709 NCBI chr 8:130,357,464...130,395,425
Ensembl chr 8:130,366,775...130,393,178
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
EXP geldanamycin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Quercetin inhibits the reaction [geldanamycin results in decreased expression of NOS2 mRNA] CTD PMID:11835313 PMID:15583003 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Npr3 natriuretic peptide receptor 3 increases expression ISO geldanamycin results in increased expression of NPR3 mRNA CTD PMID:26705709 NCBI chr 2:61,883,946...61,950,291
Ensembl chr 2:61,888,950...61,949,926
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases reduction ISO NQO1 protein results in increased reduction of geldanamycin CTD PMID:16825487 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr2c2 nuclear receptor subfamily 2, group C, member 2 increases expression ISO geldanamycin results in increased expression of NR2C2 mRNA CTD PMID:26705709 NCBI chr 4:124,005,287...124,030,349
Ensembl chr 4:124,005,280...124,030,349
JBrowse link
G Nrk Nik related kinase increases expression ISO geldanamycin results in increased expression of NRK mRNA CTD PMID:26705709 NCBI chr  X:109,940,439...110,036,361
NCBI chr  X:110,065,199...110,089,124
Ensembl chr  X:109,940,350...110,033,085
JBrowse link
G Osbpl8 oxysterol binding protein-like 8 increases expression ISO geldanamycin results in increased expression of OSBPL8 mRNA CTD PMID:26705709 NCBI chr 7:53,878,906...54,030,110
Ensembl chr 7:53,878,610...54,027,892
JBrowse link
G Otud4 OTU deubiquitinase 4 increases expression ISO geldanamycin results in increased expression of OTUD4 mRNA CTD PMID:26705709 NCBI chr19:31,895,753...31,942,509
Ensembl chr19:31,899,087...31,942,180
JBrowse link
G Oxtr oxytocin receptor increases expression ISO geldanamycin results in increased expression of OXTR mRNA CTD PMID:26705709 NCBI chr 4:144,399,326...144,417,598
Ensembl chr 4:144,403,358...144,416,116
JBrowse link
G P2rx1 purinergic receptor P2X 1 multiple interactions EXP geldanamycin promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX1] CTD PMID:11930156 NCBI chr10:59,566,268...59,581,328
Ensembl chr10:59,566,223...59,581,325
JBrowse link
G Pappa1 pappalysin 1 increases expression ISO geldanamycin results in increased expression of PAPPA mRNA CTD PMID:26705709 NCBI chr 5:80,919,932...81,153,904
Ensembl chr 5:80,920,568...81,150,940
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases degradation
ISO geldanamycin inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]; Tretinoin inhibits the reaction [geldanamycin results in increased degradation of PARP1 protein] CTD PMID:16311509 PMID:17293044 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pcbp2 poly(rC) binding protein 2 increases expression ISO geldanamycin results in increased expression of PCBP2 mRNA CTD PMID:26705709 NCBI chr 7:144,077,901...144,103,723
Ensembl chr 7:144,078,496...144,101,893
JBrowse link
G Pcm1 pericentriolar material 1 increases expression ISO geldanamycin results in increased expression of PCM1 mRNA CTD PMID:26705709 NCBI chr16:54,040,721...54,137,675
Ensembl chr16:54,040,721...54,137,660
JBrowse link
G Pde4dip phosphodiesterase 4D interacting protein increases expression ISO geldanamycin results in increased expression of PDE4DIP mRNA CTD PMID:26705709 NCBI chr 2:199,867,965...200,066,034
Ensembl chr 2:199,867,972...200,003,443
JBrowse link
G Pdgfa platelet derived growth factor subunit A increases expression ISO geldanamycin results in increased expression of PDGFA mRNA CTD PMID:26705709 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link
G Peg10 paternally expressed 10 increases expression ISO geldanamycin results in increased expression of PEG10 mRNA CTD PMID:26705709 NCBI chr 4:29,795,524...29,804,517 JBrowse link
G Pgr progesterone receptor decreases expression ISO geldanamycin results in decreased expression of PGR protein CTD PMID:11448926 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Phactr2 phosphatase and actin regulator 2 increases expression ISO geldanamycin results in increased expression of PHACTR2 mRNA CTD PMID:26705709 NCBI chr 1:7,352,050...7,633,991
Ensembl chr 1:7,355,154...7,480,825
JBrowse link
G Phldb2 pleckstrin homology-like domain, family B, member 2 increases expression ISO geldanamycin results in increased expression of PHLDB2 mRNA CTD PMID:26705709 NCBI chr11:60,042,879...60,051,229
Ensembl chr11:57,265,732...57,481,589
JBrowse link
G Phtf2 putative homeodomain transcription factor 2 increases expression ISO geldanamycin results in increased expression of PHTF2 mRNA CTD PMID:26705709 NCBI chr 4:10,823,191...10,938,273
Ensembl chr 4:10,823,281...10,938,318
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha increases expression ISO geldanamycin results in increased expression of PIK3CA mRNA CTD PMID:26705709 NCBI chr 2:118,831,350...118,861,456
Ensembl chr 2:118,831,350...118,861,454
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression ISO geldanamycin results in increased expression of PIK3R1 mRNA CTD PMID:26705709 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Plau plasminogen activator, urokinase multiple interactions ISO [geldanamycin co-treated with PTHLH protein modified form] results in decreased expression of PLAU mRNA CTD PMID:12724357 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Plppr4 phospholipid phosphatase related 4 increases expression ISO geldanamycin results in increased expression of PLPPR4 mRNA CTD PMID:26705709 NCBI chr 2:220,298,239...220,341,863
Ensembl chr 2:220,298,245...220,341,866
JBrowse link
G Plxna2 plexin A2 increases expression ISO geldanamycin results in increased expression of PLXNA2 mRNA CTD PMID:26705709 NCBI chr13:113,373,569...113,570,774
Ensembl chr13:113,373,578...113,571,648
JBrowse link
G Polr2b RNA polymerase II subunit B decreases expression ISO geldanamycin results in decreased expression of POLR2B mRNA CTD PMID:30166341 NCBI chr14:33,070,104...33,107,792
Ensembl chr14:33,070,078...33,107,776
JBrowse link
G Ppm1k protein phosphatase, Mg2+/Mn2+ dependent, 1K increases expression ISO geldanamycin results in increased expression of PPM1K mRNA CTD PMID:26705709 NCBI chr 4:88,694,395...88,721,374
Ensembl chr 4:88,694,583...88,718,533
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 increases expression ISO geldanamycin results in increased expression of PRKG1 mRNA CTD PMID:26705709 NCBI chr 1:248,982,039...250,300,952 JBrowse link
G Prmt2 protein arginine methyltransferase 2 increases expression ISO geldanamycin results in increased expression of PRMT2 mRNA CTD PMID:26705709 NCBI chr20:13,154,513...13,212,613
Ensembl chr20:13,156,241...13,212,606
JBrowse link
G Prpf6 pre-mRNA processing factor 6 increases expression ISO geldanamycin results in increased expression of PRPF6 mRNA CTD PMID:26705709 NCBI chr 3:177,098,137...177,162,937
Ensembl chr 3:177,098,073...177,162,916
JBrowse link
G Prr14l proline rich 14-like increases expression ISO geldanamycin results in increased expression of PRR14L mRNA CTD PMID:26705709 NCBI chr14:83,226,552...83,293,823
Ensembl chr14:83,226,601...83,293,822
JBrowse link
G Prrc2c proline-rich coiled-coil 2C increases expression ISO geldanamycin results in increased expression of PRRC2C mRNA CTD PMID:26705709 NCBI chr13:80,544,789...80,614,925 JBrowse link
G Psme4 proteasome activator subunit 4 increases expression ISO geldanamycin results in increased expression of PSME4 mRNA CTD PMID:26705709 NCBI chr14:115,166,165...115,269,041
Ensembl chr14:115,166,416...115,269,056
JBrowse link
G Ptar1 protein prenyltransferase alpha subunit repeat containing 1 increases expression ISO geldanamycin results in increased expression of PTAR1 mRNA CTD PMID:26705709 NCBI chr 1:241,501,679...241,557,651
Ensembl chr 1:241,501,679...241,557,651
JBrowse link
G Ptbp3 polypyrimidine tract binding protein 3 increases expression ISO geldanamycin results in increased expression of PTBP3 mRNA CTD PMID:26705709 NCBI chr 5:76,670,074...76,756,196
Ensembl chr 5:76,673,990...76,756,147
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO geldanamycin results in decreased expression of PTGS1 mRNA CTD PMID:26705709 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [[CEBPB protein binds to CEBPB protein] which binds to PTGS2 promoter]]; geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA] CTD PMID:11133817 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pthlh parathyroid hormone-like hormone multiple interactions ISO [geldanamycin co-treated with PTHLH protein modified form] results in decreased expression of PLAU mRNA; [geldanamycin co-treated with PTHLH protein modified form] results in increased expression of MMP1 mRNA CTD PMID:12724357 NCBI chr 4:181,663,425...181,674,181 JBrowse link
G Ptk2 protein tyrosine kinase 2 increases degradation
decreases phosphorylation
ISO geldanamycin results in increased degradation of PTK2 protein
geldanamycin results in decreased phosphorylation of PTK2 protein
CTD PMID:9973544 PMID:12811834 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 increases expression ISO geldanamycin results in increased expression of PTPN11 mRNA CTD PMID:26705709 NCBI chr12:40,895,515...40,955,999
Ensembl chr12:40,895,515...40,955,999
JBrowse link
G Ptpn12 protein tyrosine phosphatase, non-receptor type 12 increases expression ISO geldanamycin results in increased expression of PTPN12 mRNA CTD PMID:26705709 NCBI chr 4:10,631,129...10,702,390
Ensembl chr 4:10,631,073...10,702,386
JBrowse link
G Ptpra protein tyrosine phosphatase, receptor type, A increases expression ISO geldanamycin results in increased expression of PTPRA mRNA CTD PMID:26705709 NCBI chr 3:122,976,066...123,084,585
Ensembl chr 3:122,976,104...123,084,863
JBrowse link
G Ptprd protein tyrosine phosphatase, receptor type, D increases expression ISO geldanamycin results in increased expression of PTPRD mRNA CTD PMID:26705709 NCBI chr 5:92,862,229...93,514,071
Ensembl chr 5:92,862,267...93,244,202
JBrowse link
G Pygo1 pygopus family PHD finger 1 increases expression ISO geldanamycin results in increased expression of PYGO1 mRNA CTD PMID:26705709 NCBI chr 8:79,607,013...79,625,188
Ensembl chr 8:79,606,789...79,627,166
JBrowse link
G Rab3b RAB3B, member RAS oncogene family increases expression ISO geldanamycin results in increased expression of RAB3B mRNA CTD PMID:26705709 NCBI chr 5:128,501,789...128,568,170
Ensembl chr 5:128,501,847...128,568,188
JBrowse link
G Rabep1 rabaptin, RAB GTPase binding effector protein 1 increases expression ISO geldanamycin results in increased expression of RABEP1 mRNA CTD PMID:26705709 NCBI chr10:57,462,272...57,579,901
Ensembl chr10:57,462,447...57,579,898
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase increases expression
decreases expression
multiple interactions
ISO geldanamycin results in increased expression of RAF1 protein
geldanamycin results in decreased expression of RAF1 protein
geldanamycin results in decreased expression of and results in decreased phosphorylation of RAF1 protein
CTD PMID:8816498 PMID:19167484 PMID:24450340 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 increases expression ISO geldanamycin results in increased expression of RAPGEF2 mRNA CTD PMID:26705709 NCBI chr 2:177,836,191...178,057,378
Ensembl chr 2:177,836,202...178,057,157
JBrowse link
G Rassf8 Ras association domain family member 8 increases expression ISO geldanamycin results in increased expression of RASSF8 mRNA CTD PMID:26705709 NCBI chr 4:180,059,020...180,135,924
Ensembl chr 4:180,062,799...180,135,966
JBrowse link
G Rbak RB-associated KRAB zinc finger increases expression ISO geldanamycin results in increased expression of RBAK mRNA CTD PMID:26705709 NCBI chr12:13,428,648...13,442,279
Ensembl chr12:13,428,685...13,442,286
JBrowse link
G Rbm26 RNA binding motif protein 26 increases expression ISO geldanamycin results in increased expression of RBM26 mRNA CTD PMID:26705709 NCBI chr15:89,262,683...89,339,323
Ensembl chr15:89,266,710...89,339,323
JBrowse link
G Rbms3 RNA binding motif, single stranded interacting protein 3 increases expression ISO geldanamycin results in increased expression of RBMS3 mRNA CTD PMID:26705709 NCBI chr 8:124,833,804...125,645,895
Ensembl chr 8:124,661,839...125,645,898
JBrowse link
G Rcan1 regulator of calcineurin 1 increases expression ISO geldanamycin results in increased expression of RCAN1 mRNA CTD PMID:26705709 NCBI chr11:32,539,689...32,620,274
Ensembl chr11:32,539,683...32,550,539
JBrowse link
G Rdh10 retinol dehydrogenase 10 increases expression ISO geldanamycin results in increased expression of RDH10 mRNA CTD PMID:26705709 NCBI chr 5:2,605,265...2,631,905
Ensembl chr 5:2,603,505...2,632,030
JBrowse link
G Resf1 retroelement silencing factor 1 increases expression ISO geldanamycin results in increased expression of RESF1 mRNA CTD PMID:26705709 NCBI chr 4:183,879,177...183,905,807
Ensembl chr 4:183,896,303...183,905,297
JBrowse link
G Rfx7 regulatory factor X, 7 increases expression ISO geldanamycin results in increased expression of RFX7 mRNA CTD PMID:26705709 NCBI chr 8:79,159,297...79,279,962
Ensembl chr 8:79,159,370...79,279,962
JBrowse link
G RGD1306502 similar to hypothetical protein FLJ11193 increases expression ISO geldanamycin results in increased expression of C5ORF22 mRNA CTD PMID:26705709 NCBI chr 2:62,870,871...62,887,048
Ensembl chr 2:62,870,871...62,887,048
JBrowse link
G RGD1307929 similar to CG14967-PA increases expression ISO geldanamycin results in increased expression of KIAA0100 mRNA CTD PMID:26705709 NCBI chr10:65,523,143...65,552,629
Ensembl chr10:65,523,193...65,552,348
JBrowse link
G RGD1566359 similar to RIKEN cDNA B230219D22 increases expression ISO geldanamycin results in increased expression of C5ORF24 mRNA CTD PMID:26705709 NCBI chr17:9,454,121...9,464,076
Ensembl chr17:9,457,719...9,458,288
JBrowse link
G Rngtt RNA guanylyltransferase and 5'-phosphatase increases expression
decreases expression
ISO geldanamycin results in increased expression of RNGTT mRNA
geldanamycin results in decreased expression of RNGTT protein
CTD PMID:26705709 PMID:30166341 NCBI chr 5:48,561,325...48,779,214
Ensembl chr 5:48,561,339...48,779,207
JBrowse link
G Ro60 Ro60, Y RNA binding protein increases expression ISO geldanamycin results in increased expression of RO60 mRNA CTD PMID:26705709 NCBI chr13:60,546,892...60,567,882
Ensembl chr13:60,546,912...60,567,882
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 increases expression ISO geldanamycin results in increased expression of ROCK2 mRNA CTD PMID:26705709 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908
JBrowse link
G Rplp0 ribosomal protein lateral stalk subunit P0 decreases expression ISO geldanamycin results in decreased expression of RPLP0 mRNA CTD PMID:30166341 NCBI chr12:46,791,528...46,794,797
Ensembl chr12:46,791,528...46,794,797
JBrowse link
G Rttn rotatin increases expression ISO geldanamycin results in increased expression of RTTN mRNA CTD PMID:26705709 NCBI chr18:86,071,884...86,247,486
Ensembl chr18:86,071,662...86,247,486
JBrowse link
G Rufy2 RUN and FYVE domain containing 2 increases expression ISO geldanamycin results in increased expression of RUFY2 mRNA CTD PMID:26705709 NCBI chr20:27,219,729...27,250,006
Ensembl chr20:27,220,707...27,247,309
JBrowse link
G S100a4 S100 calcium-binding protein A4 decreases expression ISO geldanamycin results in decreased expression of S100A4 mRNA CTD PMID:26705709 NCBI chr 2:189,997,278...189,999,587
Ensembl chr 2:189,997,129...189,999,604
JBrowse link
G Samd5 sterile alpha motif domain containing 5 increases expression ISO geldanamycin results in increased expression of SAMD5 mRNA CTD PMID:26705709 NCBI chr 1:3,713,750...3,763,392
Ensembl chr 1:3,713,750...3,763,392
JBrowse link
G Sar1b secretion associated, Ras related GTPase 1B increases expression ISO geldanamycin results in increased expression of SAR1B mRNA CTD PMID:26705709 NCBI chr10:37,215,989...37,245,603
Ensembl chr10:37,215,937...37,245,658
JBrowse link
G Scrn3 secernin 3 increases expression ISO geldanamycin results in increased expression of SCRN3 mRNA CTD PMID:26705709 NCBI chr 3:60,023,970...60,048,746
Ensembl chr 3:60,024,013...60,048,746
JBrowse link
G Scyl2 SCY1 like pseudokinase 2 increases expression ISO geldanamycin results in increased expression of SCYL2 mRNA CTD PMID:26705709 NCBI chr 7:30,291,087...30,344,464
Ensembl chr 7:30,291,087...30,344,445
JBrowse link
G Sema3d semaphorin 3D increases expression ISO geldanamycin results in increased expression of SEMA3D mRNA CTD PMID:26705709 NCBI chr 4:19,224,378...19,413,519
Ensembl chr 4:19,224,310...19,413,484
JBrowse link
G Senp1 SUMO specific peptidase 1 increases expression ISO geldanamycin results in increased expression of SENP1 mRNA CTD PMID:26705709 NCBI chr 7:139,626,444...139,684,587
Ensembl chr 7:139,630,515...139,675,245
JBrowse link
G Serpine1 serpin family E member 1 increases expression ISO geldanamycin results in increased expression of SERPINE1 mRNA CTD PMID:26705709 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Sesn3 sestrin 3 increases expression ISO geldanamycin results in increased expression of SESN3 mRNA CTD PMID:26705709 NCBI chr 8:12,823,060...12,878,749
Ensembl chr 8:12,823,155...12,872,705
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase increases expression ISO geldanamycin results in increased expression of SETD2 mRNA CTD PMID:26705709 NCBI chr 8:118,802,478...118,888,224
Ensembl chr 8:118,803,075...118,888,224
JBrowse link
G Setx senataxin increases expression ISO geldanamycin results in increased expression of SETX mRNA CTD PMID:26705709 NCBI chr 3:7,680,430...7,731,815
Ensembl chr 3:7,686,503...7,730,539
JBrowse link
G Sfpq splicing factor proline and glutamine rich increases expression ISO geldanamycin results in increased expression of SFPQ mRNA CTD PMID:26705709 NCBI chr 5:145,079,803...145,088,517
Ensembl chr 5:145,079,803...145,088,498
JBrowse link
G Sgms2 sphingomyelin synthase 2 increases expression ISO geldanamycin results in increased expression of SGMS2 mRNA CTD PMID:26705709 NCBI chr 2:236,458,276...236,530,667
Ensembl chr 2:236,458,279...236,480,502
JBrowse link
G Sike1 suppressor of IKBKE 1 increases expression ISO geldanamycin results in increased expression of SIKE1 mRNA CTD PMID:26705709 NCBI chr 2:205,488,182...205,496,013
Ensembl chr 2:205,488,182...205,496,012
JBrowse link
G Slain2 SLAIN motif family, member 2 increases expression ISO geldanamycin results in increased expression of SLAIN2 mRNA CTD PMID:26705709 NCBI chr14:37,802,347...37,880,571
Ensembl chr14:37,802,365...37,871,051
JBrowse link
G Slc16a1 solute carrier family 16 member 1 increases expression ISO geldanamycin results in increased expression of SLC16A1 mRNA CTD PMID:26705709 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554
JBrowse link
G Slc16a7 solute carrier family 16 member 7 increases expression ISO geldanamycin results in increased expression of SLC16A7 mRNA CTD PMID:26705709 NCBI chr 7:68,438,341...68,606,312
Ensembl chr 7:68,446,193...68,549,763
JBrowse link
G Slc2a13 solute carrier family 2 member 13 increases expression ISO geldanamycin results in increased expression of SLC2A13 mRNA CTD PMID:26705709 NCBI chr 7:132,430,852...132,757,558
Ensembl chr 7:132,430,853...132,757,558
JBrowse link
G Slc38a1 solute carrier family 38, member 1 increases expression ISO geldanamycin results in increased expression of SLC38A1 mRNA CTD PMID:26705709 NCBI chr 7:137,970,555...138,040,098
Ensembl chr 7:137,975,549...138,039,984
JBrowse link
G Slc39a6 solute carrier family 39 member 6 increases expression ISO geldanamycin results in increased expression of SLC39A6 mRNA CTD PMID:26705709 NCBI chr18:16,523,450...16,543,992
Ensembl chr18:16,522,982...16,543,992
JBrowse link
G Slc8a1 solute carrier family 8 member A1 increases expression ISO geldanamycin results in increased expression of SLC8A1 mRNA CTD PMID:26705709 NCBI chr 6:4,244,076...4,564,262
Ensembl chr 6:4,258,991...4,520,604
JBrowse link
G Slfn5 schlafen family member 5 increases expression ISO geldanamycin results in increased expression of SLFN5 mRNA CTD PMID:26705709 NCBI chr10:70,298,094...70,312,062
Ensembl chr10:70,298,519...70,312,070
JBrowse link
G Smarca2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 increases expression ISO geldanamycin results in increased expression of SMARCA2 mRNA CTD PMID:26705709 NCBI chr 1:244,615,811...244,783,736
Ensembl chr 1:244,615,821...244,782,706
JBrowse link
G Smc1a structural maintenance of chromosomes 1A increases expression ISO geldanamycin results in increased expression of SMC1A mRNA CTD PMID:26705709 NCBI chr  X:21,710,976...21,755,708
Ensembl chr  X:21,711,019...21,755,525
JBrowse link
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 increases expression ISO geldanamycin results in increased expression of SMCHD1 mRNA CTD PMID:26705709 NCBI chr 9:119,675,750...119,818,620
Ensembl chr 9:119,676,628...119,818,310
JBrowse link
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 increases expression ISO geldanamycin results in increased expression of SOS2 mRNA CTD PMID:26705709 NCBI chr 6:91,885,292...92,008,059
Ensembl chr 6:91,883,425...92,007,957
JBrowse link
G Sp4 Sp4 transcription factor increases expression ISO geldanamycin results in increased expression of SP4 mRNA CTD PMID:26705709 NCBI chr 6:146,135,877...146,201,344
Ensembl chr 6:146,135,877...146,195,819
JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 increases expression ISO geldanamycin results in increased expression of SPTBN1 mRNA CTD PMID:26705709 NCBI chr14:114,517,839...114,700,199
Ensembl chr14:114,518,816...114,692,764
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO
EXP
geldanamycin inhibits the reaction [HSP90AA1 protein binds to SRC protein binds to CDC37 protein]; geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of SRC protein]
geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased localization of SRC protein]
CTD PMID:10401681 PMID:17223712 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Srpra SRP receptor subunit alpha increases expression ISO geldanamycin results in increased expression of SRPR mRNA CTD PMID:26705709 NCBI chr 8:36,410,683...36,416,766
Ensembl chr 8:36,410,683...36,416,296
JBrowse link
G Srrm2 serine/arginine repetitive matrix 2 increases expression ISO geldanamycin results in increased expression of SRRM2 mRNA CTD PMID:26705709 NCBI chr10:13,128,820...13,162,956
Ensembl chr10:13,145,099...13,162,343
JBrowse link
G Srrt serrate, RNA effector molecule increases expression ISO geldanamycin results in increased expression of SRRT mRNA CTD PMID:26705709 NCBI chr12:22,457,898...22,471,090 JBrowse link
G Strn4 striatin 4 decreases expression ISO geldanamycin results in decreased expression of STRN4 mRNA CTD PMID:30166341 NCBI chr 1:78,739,930...78,765,696
Ensembl chr 1:78,735,678...78,765,692
JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 multiple interactions ISO geldanamycin inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; geldanamycin promotes the reaction [ESR1 protein binds to STUB1 protein]; STUB1 protein promotes the reaction [geldanamycin results in increased degradation of ESR1 protein] CTD PMID:16037132 PMID:25645596 NCBI chr10:15,197,754...15,200,035
Ensembl chr10:15,197,803...15,200,117
JBrowse link
G Supt16h SPT16 homolog, facilitates chromatin remodeling subunit increases expression ISO geldanamycin results in increased expression of SUPT16H mRNA CTD PMID:26705709 NCBI chr15:28,574,841...28,611,959
Ensembl chr15:28,575,480...28,611,946
JBrowse link
G Tead1 TEA domain transcription factor 1 increases expression ISO geldanamycin results in increased expression of TEAD1 mRNA CTD PMID:26705709 NCBI chr 1:177,495,500...177,714,795
Ensembl chr 1:177,495,782...177,707,061
JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 increases expression ISO geldanamycin results in increased expression of TET2 mRNA CTD PMID:26705709 NCBI chr 2:238,719,389...238,802,975
Ensembl chr 2:238,720,835...238,803,024
JBrowse link
G Tfpi tissue factor pathway inhibitor increases expression ISO geldanamycin results in increased expression of TFPI mRNA CTD PMID:26705709 NCBI chr 3:71,852,738...71,902,127
Ensembl chr 3:71,852,744...71,893,618
JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression ISO geldanamycin results in increased expression of TGFB2 mRNA CTD PMID:26705709 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Thbs1 thrombospondin 1 increases expression ISO geldanamycin results in increased expression of THBS1 mRNA CTD PMID:26705709 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Tle4 TLE family member 4, transcriptional corepressor increases expression ISO geldanamycin results in increased expression of TLE4 mRNA CTD PMID:26705709 NCBI chr 1:231,394,606...231,531,396
Ensembl chr 1:231,393,379...231,530,786
JBrowse link
G Tll1 tolloid-like 1 increases expression ISO geldanamycin results in increased expression of TLL1 mRNA CTD PMID:26705709 NCBI chr16:27,399,467...27,597,240
Ensembl chr16:27,399,467...27,597,240
JBrowse link
G Tlr4 toll-like receptor 4 increases expression ISO geldanamycin results in increased expression of TLR4 mRNA CTD PMID:26705709 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tmem33 transmembrane protein 33 increases expression ISO geldanamycin results in increased expression of TMEM33 mRNA CTD PMID:26705709 NCBI chr14:42,537,352...42,559,580
Ensembl chr14:42,535,701...42,560,174
JBrowse link
G Tmod3 tropomodulin 3 increases expression ISO geldanamycin results in increased expression of TMOD3 mRNA CTD PMID:26705709 NCBI chr 8:82,432,165...82,492,243
Ensembl chr 8:82,432,169...82,492,243
JBrowse link
G Tmtc3 transmembrane O-mannosyltransferase targeting cadherins 3 increases expression ISO geldanamycin results in increased expression of TMTC3 mRNA CTD PMID:26705709 NCBI chr 7:40,171,957...40,217,056
Ensembl chr 7:40,171,963...40,217,056
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO geldanamycin inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; geldanamycin inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]
geldanamycin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]
CTD PMID:11472980 PMID:12571865 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf26 tumor necrosis factor receptor superfamily, member 26 increases expression ISO geldanamycin results in increased expression of TNFRSF10D mRNA CTD PMID:26705709 NCBI chr 1:216,808,642...216,829,361
Ensembl chr 1:216,808,632...216,828,651
JBrowse link
G Tnfsf15 TNF superfamily member 15 decreases expression ISO geldanamycin results in decreased expression of TNFSF15 mRNA CTD PMID:26705709 NCBI chr 5:79,553,935...79,569,974
Ensembl chr 5:79,553,742...79,570,073
JBrowse link
G Tnks2 tankyrase 2 increases expression ISO geldanamycin results in increased expression of TNKS2 mRNA CTD PMID:26705709
G Tob2 transducer of ERBB2, 2 increases expression ISO geldanamycin results in increased expression of TOB2 mRNA CTD PMID:26705709 NCBI chr 7:123,079,520...123,088,240
Ensembl chr 7:123,079,537...123,088,279
JBrowse link
G Tp53 tumor protein p53 affects localization
affects expression
multiple interactions
ISO geldanamycin affects the localization of TP53 protein
geldanamycin affects the expression of TP53 protein
Tretinoin inhibits the reaction [geldanamycin affects the localization of TP53 protein]
CTD PMID:17293044 PMID:24211270 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 increases expression ISO geldanamycin results in increased expression of TP53BP1 mRNA CTD PMID:26705709 NCBI chr 3:113,160,030...113,259,701
Ensembl chr 3:113,160,000...113,231,790
JBrowse link
G Tpm4 tropomyosin 4 increases expression ISO geldanamycin results in increased expression of TPM4 mRNA CTD PMID:26705709 NCBI chr16:19,385,810...19,399,851
Ensembl chr16:19,385,736...19,399,903
JBrowse link
G Tpp2 tripeptidyl peptidase 2 increases expression ISO geldanamycin results in increased expression of TPP2 mRNA CTD PMID:26705709 NCBI chr 9:50,664,048...50,744,803
NCBI chr 9:50,578,868...50,628,943
Ensembl chr 9:50,581,234...50,744,803
JBrowse link
G Tpr translocated promoter region, nuclear basket protein increases expression ISO geldanamycin results in increased expression of TPR mRNA CTD PMID:26705709 NCBI chr13:67,611,685...67,672,833
Ensembl chr13:67,611,708...67,672,827
JBrowse link
G Trim59 tripartite motif-containing 59 increases expression ISO geldanamycin results in increased expression of TRIM59 mRNA CTD PMID:26705709 NCBI chr 2:165,629,903...165,641,751
Ensembl chr 2:165,629,918...165,641,573
JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 increases expression ISO geldanamycin results in increased expression of TRPC6 mRNA CTD PMID:26705709 NCBI chr 8:6,811,543...6,917,534
Ensembl chr 8:6,811,543...6,917,535
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions EXP geldanamycin affects the reaction [Capsaicin results in increased activity of TRPV1] CTD PMID:11930156 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link
G Ttc3 tetratricopeptide repeat domain 3 increases expression ISO geldanamycin results in increased expression of TTC3 mRNA CTD PMID:26705709 NCBI chr11:34,598,324...34,739,986
Ensembl chr11:34,598,492...34,738,791
JBrowse link
G Ttc37 tetratricopeptide repeat domain 37 increases expression ISO geldanamycin results in increased expression of TTC37 mRNA CTD PMID:26705709 NCBI chr 2:2,891,265...3,037,602
Ensembl chr 2:2,903,492...3,004,553
JBrowse link
G Tuba1a tubulin, alpha 1A decreases expression ISO geldanamycin results in decreased expression of TUBA1A mRNA CTD PMID:27015953 NCBI chr 7:140,637,287...140,640,953
Ensembl chr 7:140,637,287...140,640,953
JBrowse link
G Ube2h ubiquitin-conjugating enzyme E2H increases expression ISO geldanamycin results in increased expression of UBE2H mRNA CTD PMID:26705709 NCBI chr 4:57,511,418...57,625,147
Ensembl chr 4:57,511,418...57,625,257
JBrowse link
G Ubn2 ubinuclein 2 increases expression ISO geldanamycin results in increased expression of UBN2 mRNA CTD PMID:26705709 NCBI chr 4:66,164,639...66,254,297
Ensembl chr 4:66,165,845...66,233,230
JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase increases expression ISO geldanamycin results in increased expression of UGCG mRNA CTD PMID:26705709 NCBI chr 5:76,376,722...76,419,564
Ensembl chr 5:76,386,836...76,419,560
JBrowse link
G Uggt1 UDP-glucose glycoprotein glucosyltransferase 1 increases expression ISO geldanamycin results in increased expression of UGGT1 mRNA CTD PMID:26705709 NCBI chr 9:42,692,156...42,805,680
Ensembl chr 9:42,692,105...42,805,673
JBrowse link
G Uhmk1 U2AF homology motif kinase 1 increases expression ISO geldanamycin results in increased expression of UHMK1 mRNA CTD PMID:26705709 NCBI chr13:88,521,625...88,536,728
Ensembl chr13:88,521,625...88,536,728
JBrowse link
G Usp10 ubiquitin specific peptidase 10 increases expression ISO geldanamycin results in increased expression of USP10 mRNA CTD PMID:26705709 NCBI chr19:52,566,274...52,608,820
Ensembl chr19:52,566,607...52,608,817
JBrowse link
G Usp12 ubiquitin specific peptidase 12 increases expression ISO geldanamycin results in increased expression of USP12 mRNA CTD PMID:26705709 NCBI chr12:10,037,686...10,087,685
Ensembl chr12:10,063,117...10,087,685
JBrowse link
G Usp25 ubiquitin specific peptidase 25 increases expression ISO geldanamycin results in increased expression of USP25 mRNA CTD PMID:26705709 NCBI chr11:15,436,080...15,558,646
Ensembl chr11:15,436,269...15,558,646
JBrowse link
G Usp36 ubiquitin specific peptidase 36 increases expression ISO geldanamycin results in increased expression of USP36 mRNA CTD PMID:26705709 NCBI chr10:107,292,828...107,324,355
Ensembl chr10:107,292,828...107,324,355
JBrowse link
G Vapb VAMP associated protein B and C increases expression ISO geldanamycin results in increased expression of VAPB mRNA CTD PMID:26705709 NCBI chr 3:171,832,558...171,871,042
Ensembl chr 3:171,832,500...171,868,647
JBrowse link
G Vdac3 voltage-dependent anion channel 3 decreases expression ISO geldanamycin results in decreased expression of VDAC3 mRNA CTD PMID:30166341 NCBI chr16:74,292,466...74,308,910
Ensembl chr16:74,292,438...74,308,903
JBrowse link
G Vldlr very low density lipoprotein receptor multiple interactions EXP geldanamycin inhibits the reaction [IL1B protein results in decreased expression of VLDLR protein] CTD PMID:15808840 NCBI chr 1:245,236,819...245,273,688
Ensembl chr 1:245,237,736...245,269,205
JBrowse link
G Vmp1 vacuole membrane protein 1 increases expression ISO geldanamycin results in increased expression of VMP1 mRNA CTD PMID:26705709 NCBI chr10:73,901,988...74,001,900
Ensembl chr10:73,902,837...74,001,895
JBrowse link
G Vps50 VPS50 subunit of EARP/GARPII complex increases expression ISO geldanamycin results in increased expression of VPS50 mRNA CTD PMID:26705709 NCBI chr 4:28,441,255...28,551,784
Ensembl chr 4:28,441,301...28,551,784
JBrowse link
G Zbed6 zinc finger, BED-type containing 6 increases expression ISO geldanamycin results in increased expression of ZBED6 mRNA CTD PMID:26705709 NCBI chr13:50,196,143...50,211,670 JBrowse link
G Zc3h11a zinc finger CCCH-type containing 11A increases expression ISO geldanamycin results in increased expression of ZC3H11A mRNA CTD PMID:26705709 NCBI chr13:50,196,042...50,234,862
Ensembl chr13:50,196,042...50,234,862
JBrowse link
G Zfhx4 zinc finger homeobox 4 increases expression ISO geldanamycin results in increased expression of ZFHX4 mRNA CTD PMID:26705709 NCBI chr 2:98,423,565...98,610,368
Ensembl chr 2:98,423,569...98,610,368
JBrowse link
G Zfp207 zinc finger protein 207 decreases expression ISO geldanamycin results in decreased expression of ZNF207 mRNA CTD PMID:30166341 NCBI chr10:67,762,970...67,784,854
Ensembl chr10:67,762,995...67,774,787
JBrowse link
G Zfp326 zinc finger protein 326 increases expression ISO geldanamycin results in increased expression of ZNF326 mRNA CTD PMID:26705709 NCBI chr14:4,998,530...5,006,759
NCBI chr14:5,016,764...5,036,663
Ensembl chr14:4,998,539...5,033,942
JBrowse link
G Zfp518a zinc finger protein 518A increases expression ISO geldanamycin results in increased expression of ZNF518A mRNA CTD PMID:26705709 NCBI chr 1:260,152,881...260,178,360
Ensembl chr 1:260,153,645...260,178,349
JBrowse link
G Zfp638 zinc finger protein 638 increases expression ISO geldanamycin results in increased expression of ZNF638 mRNA CTD PMID:26705709 NCBI chr 4:115,555,185...115,690,272
Ensembl chr 4:115,601,661...115,690,272
JBrowse link
G Zfp655 zinc finger protein 655 increases expression ISO geldanamycin results in increased expression of ZNF655 mRNA CTD PMID:26705709 NCBI chr12:11,122,779...11,146,182
Ensembl chr12:11,127,754...11,144,754
JBrowse link
G Zfp704 zinc finger protein 704 increases expression ISO geldanamycin results in increased expression of ZNF704 mRNA CTD PMID:26705709 NCBI chr 2:94,377,059...94,559,838
Ensembl chr 2:94,377,072...94,551,529
JBrowse link
G Zfp711 zinc finger protein 711 increases expression ISO geldanamycin results in increased expression of ZNF711 mRNA CTD PMID:26705709 NCBI chr  X:84,062,363...84,095,888
Ensembl chr  X:84,064,427...84,096,617
JBrowse link
G Zfp770 zinc finger protein 770 increases expression ISO geldanamycin results in increased expression of ZNF770 mRNA CTD PMID:26705709 NCBI chr 3:105,658,970...105,667,227
Ensembl chr 3:105,661,044...105,663,457
JBrowse link
G Zfr zinc finger RNA binding protein increases expression ISO geldanamycin results in increased expression of ZFR mRNA CTD PMID:26705709 NCBI chr 2:62,150,251...62,213,048
Ensembl chr 2:62,150,251...62,213,048
JBrowse link
G Zfx zinc finger protein X-linked increases expression ISO geldanamycin results in increased expression of ZFX mRNA CTD PMID:26705709 NCBI chr  X:63,158,368...63,204,971
Ensembl chr  X:63,158,976...63,204,530
JBrowse link
G Zmynd11 zinc finger, MYND-type containing 11 increases expression ISO geldanamycin results in increased expression of ZMYND11 mRNA CTD PMID:26705709 NCBI chr17:63,825,616...63,914,740
Ensembl chr17:63,825,627...63,879,171
JBrowse link
G Znf660 zinc finger protein 660 increases expression ISO geldanamycin results in increased expression of ZNF660 mRNA CTD PMID:26705709 NCBI chr 8:131,955,636...131,968,550
Ensembl chr 8:131,965,134...131,966,540
JBrowse link
G Zxdc ZXD family zinc finger C increases expression ISO geldanamycin results in increased expression of ZXDC mRNA CTD PMID:26705709 NCBI chr 4:122,282,119...122,314,251
Ensembl chr 4:122,282,279...122,312,879
JBrowse link
rifabutin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadac arylacetamide deacetylase multiple interactions
decreases acetylation
ISO AADAC mRNA affects the reaction [Rifabutin results in increased expression of CYP3A4 mRNA]; bis(4-nitrophenyl)phosphate inhibits the reaction [AADAC protein results in decreased acetylation of Rifabutin]; Isoflurophate inhibits the reaction [AADAC protein results in decreased acetylation of Rifabutin]; Phenylmethylsulfonyl Fluoride inhibits the reaction [AADAC protein results in decreased acetylation of Rifabutin]; Physostigmine inhibits the reaction [AADAC protein results in decreased acetylation of Rifabutin]; Sodium Fluoride inhibits the reaction [AADAC protein results in decreased acetylation of Rifabutin] CTD PMID:21856291 NCBI chr 2:150,146,234...150,157,480
Ensembl chr 2:150,146,234...150,157,480
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO Rifabutin results in decreased activity of ABCB11 protein CTD PMID:20829430 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 multiple interactions
increases expression
ISO AADAC mRNA affects the reaction [Rifabutin results in increased expression of CYP3A4 mRNA] CTD PMID:16837568 PMID:21856291 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
rifampicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadac arylacetamide deacetylase multiple interactions
increases hydrolysis
decreases acetylation
ISO AADAC mRNA affects the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; bis(4-nitrophenyl)phosphate inhibits the reaction [AADAC protein results in decreased acetylation of Rifampin]; Isoflurophate inhibits the reaction [AADAC protein results in decreased acetylation of Rifampin]; Phenylmethylsulfonyl Fluoride inhibits the reaction [AADAC protein results in decreased acetylation of Rifampin]; Physostigmine inhibits the reaction [AADAC protein results in decreased acetylation of Rifampin]; Sodium Fluoride inhibits the reaction [AADAC protein results in decreased acetylation of Rifampin]
AADAC protein results in increased hydrolysis of Rifampin
CTD PMID:21856291 PMID:22207054 NCBI chr 2:150,146,234...150,157,480
Ensembl chr 2:150,146,234...150,157,480
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 decreases expression
increases expression
ISO Rifampin results in decreased expression of ABCA1 mRNA; Rifampin results in decreased expression of ABCA1 protein
Rifampin results in increased expression of ABCA1 mRNA; Rifampin results in increased expression of ABCA1 protein
CTD PMID:15883047 PMID:17088262 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abca2 ATP binding cassette subfamily A member 2 increases expression ISO Rifampin results in increased expression of ABCA2 mRNA CTD PMID:27199754 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809
JBrowse link
G Abca8 ATP binding cassette subfamily A member 8 decreases expression ISO Rifampin results in decreased expression of ABCA8 mRNA CTD PMID:27199754 NCBI chr10:98,236,919...98,308,288
Ensembl chr10:98,237,141...98,294,522
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression
decreases activity
multiple interactions
ISO
EXP
Rifampin results in decreased expression of ABCB11 mRNA
Rifampin results in decreased activity of ABCB11 protein
Rifampin inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
CTD PMID:12135489 PMID:16837569 PMID:20829430 PMID:24014644 PMID:28437613 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases expression
decreases activity
affects activity
ISO
EXP
[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA; [NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein; [Rifampin binds to and results in increased activity of NR1I2 protein] promotes the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 protein; Camptothecin inhibits the reaction [Rifampin results in increased expression of ABCB1 mRNA]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of ABCB1 mRNA]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of ABCB1 protein]; mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA]; mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]; pimecrolimus inhibits the reaction [Rifampin results in increased expression of ABCB1 mRNA]; resveratrol inhibits the reaction [Rifampin results in increased expression of ABCB1 protein]; Rifampin promotes the reaction [ABCB1 protein results in increased transport of Digoxin]
Rifampin results in increased expression of ABCB1 mRNA; Rifampin results in increased expression of ABCB1 protein
[Rifampin metabolite results in decreased activity of ABCB1A protein] which results in decreased abundance of Adenosine Triphosphate
Rifampin affects the activity of ABCB1 protein
CTD PMID:8632764 PMID:11744607 PMID:14722322 PMID:15276086 PMID:15290871 PMID:15710169 PMID:15964336 PMID:16819505 PMID:16837569 PMID:16842400 PMID:17003290 PMID:17191263 PMID:17365992 PMID:18094037 PMID:19148864 PMID:19647009 PMID:20018165 PMID:20041327 PMID:20624464 PMID:22258563 PMID:22914566 PMID:23685082 PMID:23707768 PMID:24259679 PMID:24552687 PMID:25313206 PMID:25542144 PMID:26301745 PMID:26394120 PMID:27199754 PMID:27871908 PMID:27918128 PMID:29356861 PMID:30071242 PMID:31233785 PMID:32092453 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression ISO Rifampin results in increased expression of ABCB4 mRNA CTD PMID:27199754 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 increases expression ISO Rifampin results in increased expression of ABCB6 mRNA CTD PMID:27199754 NCBI chr 9:82,373,950...82,382,228
Ensembl chr 9:82,373,946...82,382,272
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO Rifampin results in increased expression of ABCC1 mRNA CTD PMID:17191263 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc10 ATP binding cassette subfamily C member 10 increases expression ISO Rifampin results in increased expression of ABCC10 mRNA CTD PMID:27199754 NCBI chr 9:17,041,351...17,061,263
Ensembl chr 9:17,041,389...17,063,780
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects export
increases expression
multiple interactions
ISO ABCC2 protein affects the export of Rifampin
Rifampin results in increased expression of ABCC2; Rifampin results in increased expression of ABCC2 mRNA; Rifampin results in increased expression of ABCC2 protein
[Rifampin co-treated with ABCC2 gene mutant form] results in increased expression of ABCC3 protein
CTD PMID:11836020 PMID:12206135 PMID:15652233 PMID:16837569 PMID:16952291 PMID:20832446 PMID:25313206 PMID:27199754 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions
increases expression
increases activity
ISO [Rifampin co-treated with ABCC2 gene mutant form] results in increased expression of ABCC3 protein; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA; Rifampin inhibits the reaction [Decitabine results in increased expression of ABCC3 mRNA]
Rifampin results in increased expression of ABCC3 mRNA
Rifampin results in increased activity of ABCC3 protein
CTD PMID:14570758 PMID:16837569 PMID:16952291 PMID:19041851 PMID:20832446 PMID:23137910 PMID:27199754 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 increases expression ISO Rifampin results in increased expression of ABCC5 mRNA CTD PMID:19041851 NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 increases expression ISO Rifampin results in increased expression of ABCC6 mRNA CTD PMID:27199754 NCBI chr 1:101,954,786...102,013,252
Ensembl chr 1:101,959,540...102,013,243
JBrowse link
G Abcf1 ATP binding cassette subfamily F member 1 increases expression ISO Rifampin results in increased expression of ABCF1 mRNA CTD PMID:27199754 NCBI chr20:3,309,914...3,322,828
Ensembl chr20:3,309,899...3,322,825
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 increases expression ISO Rifampin results in increased expression of ABCG1 mRNA; Rifampin results in increased expression of ABCG1 protein CTD PMID:12040753 PMID:17088262 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO Rifampin results in increased expression of ABCG2 mRNA CTD PMID:16837569 PMID:27199754 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression ISO Rifampin results in increased expression of ABCG8 mRNA CTD PMID:27199754 NCBI chr 6:7,961,413...7,980,708
Ensembl chr 6:7,961,413...7,980,708
JBrowse link
G Abi3 ABI family, member 3 decreases expression ISO Rifampin results in decreased expression of ABI3 mRNA CTD PMID:24552687 NCBI chr10:83,644,086...83,655,182
Ensembl chr10:83,644,086...83,655,182
JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases expression ISO Rifampin results in increased expression of ACACA mRNA CTD PMID:27806127 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Actr10 actin related protein 10 increases expression ISO Rifampin results in increased expression of ACTR10 mRNA CTD PMID:24552687 NCBI chr 6:93,385,457...93,411,605
Ensembl chr 6:93,385,457...93,411,576
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) increases expression ISO Rifampin results in increased expression of ADH1C mRNA CTD PMID:12040753 NCBI chr 2:243,550,655...243,562,243
Ensembl chr 2:243,550,627...243,687,857
JBrowse link
G Adora2a adenosine A2a receptor decreases expression ISO Rifampin results in decreased expression of ADORA2A mRNA CTD PMID:24552687 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 decreases expression ISO Rifampin results in decreased expression of AGAP2 mRNA CTD PMID:24552687 NCBI chr 7:70,360,199...70,377,422
Ensembl chr 7:70,364,813...70,377,422
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases expression
ISO [Rifampin co-treated with Benzo(a)pyrene] results in increased expression of AHR mRNA; [Rifampin co-treated with Monocrotophos] results in decreased expression of AHR mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of AHR protein; NR1I2 protein inhibits the reaction [[Rifampin co-treated with Benzo(a)pyrene] results in increased expression of AHR mRNA]
Rifampin results in increased expression of AHR mRNA; Rifampin results in increased expression of AHR protein
CTD PMID:22733800 PMID:28428138 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression
multiple interactions
ISO Rifampin results in increased expression of AKR1B10 mRNA
pazopanib inhibits the reaction [Rifampin results in increased expression of AKR1B10 mRNA]; pimecrolimus inhibits the reaction [Rifampin results in increased expression of AKR1B10 mRNA]
CTD PMID:29356861 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 increases expression ISO Rifampin results in increased expression of ALAS1 mRNA CTD PMID:24259679 PMID:24552687 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177
JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of ANGPTL4 mRNA CTD PMID:21127053 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Ankrd65 ankyrin repeat domain 65 decreases expression ISO Rifampin results in decreased expression of ANKRD65 mRNA CTD PMID:24552687 NCBI chr 5:173,237,642...173,239,899
Ensembl chr 5:173,237,642...173,239,899
JBrowse link
G Anks1b ankyrin repeat and sterile alpha motif domain containing 1B decreases expression ISO Rifampin results in decreased expression of ANKS1B mRNA CTD PMID:24552687 NCBI chr 7:30,507,135...31,684,604
Ensembl chr 7:30,699,476...31,681,182
JBrowse link
G Anxa5 annexin A5 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of ANXA5 mRNA CTD PMID:21224054 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of AQP3 mRNA CTD PMID:21127053 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Aqp4 aquaporin 4 decreases expression ISO Rifampin results in decreased expression of AQP4 mRNA CTD PMID:24552687 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Arsj arylsulfatase family, member J decreases expression ISO Rifampin results in decreased expression of ARSJ mRNA CTD PMID:24552687 NCBI chr 2:230,163,014...230,662,084 JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression
EXP
ISO
ATF4 mutant form inhibits the reaction [Rifampin results in increased expression of HSPA5 protein]
Rifampin results in increased expression of ATF4 mRNA; Rifampin results in increased expression of ATF4 protein
4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of ATF4 protein]
CTD PMID:24638036 PMID:27470132 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions
decreases expression
ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM protein
Rifampin results in decreased expression of ATM mRNA
CTD PMID:21224054 PMID:24552687 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 increases expression
multiple interactions
ISO Rifampin results in increased expression of ATP6V0A1 protein
[Rotenone co-treated with Rifampin] results in increased expression of ATP6V0A1 protein; Rifampin inhibits the reaction [Rotenone results in decreased expression of ATP6V0A1 mRNA]; Rotenone inhibits the reaction [Rifampin results in increased expression of ATP6V0A1 protein]
CTD PMID:31648047 NCBI chr10:88,914,264...88,967,736
Ensembl chr10:88,914,276...88,967,748
JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit D1 multiple interactions ISO ATP6V0D1 protein affects the reaction [Rifampin inhibits the reaction [Rotenone results in increased lipidation of MAP1LC3B protein]] CTD PMID:31648047 NCBI chr19:37,481,782...37,525,762
Ensembl chr19:37,481,782...37,525,762
JBrowse link
G Atrx ATRX, chromatin remodeler increases expression ISO Rifampin results in increased expression of ATRX mRNA CTD PMID:24552687 NCBI chr  X:76,820,110...76,979,155
Ensembl chr  X:76,692,970...76,708,878
Ensembl chr  X:76,692,970...76,708,878
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
decreases expression
ISO [Isoniazid co-treated with Rifampin] results in increased expression of BAX protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of BAX mRNA; Ursodeoxycholic Acid inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased expression of BAX protein]
[Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in increased expression of BAX protein
Rifampin results in decreased expression of BAX protein
CTD PMID:11958592 PMID:12645856 PMID:21224054 PMID:21419764 PMID:31629065 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions
ISO Rifampin results in increased expression of BCL2 protein
[Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of BCL2 protein
[Isoniazid co-treated with Rifampin] results in decreased expression of BCL2 protein; Ursodeoxycholic Acid inhibits the reaction [[Isoniazid co-treated with Rifampin] results in decreased expression of BCL2 protein]
CTD PMID:11958592 PMID:21419764 PMID:31629065 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
multiple interactions
ISO Rifampin results in increased expression of BCL2L1 protein
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of BCL2L1 mRNA
CTD PMID:11958592 PMID:12645856 PMID:21224054 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of BHLHE40 mRNA CTD PMID:21127053 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G Bmp4 bone morphogenetic protein 4 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of BMP4 mRNA CTD PMID:21127053 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Car1 carbonic anhydrase 1 decreases expression ISO Rifampin results in decreased expression of CA1 mRNA CTD PMID:24552687 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479
JBrowse link
G Casp1 caspase 1 multiple interactions ISO Rifampin inhibits the reaction [Rotenone results in increased cleavage of CASP1 protein] CTD PMID:26086368 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp3 caspase 3 multiple interactions ISO Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased activity of CASP3 protein]]; Rifampin inhibits the reaction [[Acetaminophen co-treated with [ferric nitrate results in increased abundance of Iron]] results in increased cleavage of CASP3 protein]; Rifampin inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]; Rifampin inhibits the reaction [FAS protein results in increased activity of CASP3 protein]; Rifampin inhibits the reaction [Staurosporine results in increased cleavage of CASP3 protein]; Rifampin promotes the reaction [Galactosamine results in increased activity of CASP3 protein]
[Isoniazid co-treated with Rifampin] results in increased activity of CASP3 protein; HGF protein inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased activity of CASP3 protein]; Ursodeoxycholic Acid inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased activity of CASP3 protein]
CTD PMID:11958592 PMID:12645856 PMID:17936189 PMID:21419764 PMID:23764483 PMID:26775663 PMID:31678598 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions ISO Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased activity of CASP8 protein]]; Rifampin inhibits the reaction [FAS protein results in increased activity of CASP8 protein] CTD PMID:11958592 PMID:12645856 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression EXP Rifampin results in decreased expression of CCL2 mRNA CTD PMID:25051504 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression EXP Rifampin results in decreased expression of CCL5 protein CTD PMID:25051504 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CCN1 mRNA CTD PMID:21127053 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CCND1 mRNA CTD PMID:21224054 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccng1 cyclin G1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CCNG1 mRNA CTD PMID:21224054 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Ccr6 C-C motif chemokine receptor 6 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CCR6 mRNA CTD PMID:21127053 NCBI chr 1:53,063,380...53,087,519
Ensembl chr 1:53,065,025...53,087,474
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CCR7 mRNA CTD PMID:21127053 NCBI chr10:87,057,335...87,067,444
Ensembl chr10:87,057,136...87,067,456
JBrowse link
G Cd36 CD36 molecule increases expression ISO Rifampin results in increased expression of CD36 mRNA CTD PMID:27806127 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A protein CTD PMID:21224054 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CDKN2B mRNA CTD PMID:21127053 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO Rifampin results in increased expression of CES1 protein CTD PMID:10640517 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Ces2h carboxylesterase 2H increases expression
multiple interactions
ISO Rifampin results in increased expression of CES2 mRNA; Rifampin results in increased expression of CES2 protein
Dichlororibofuranosylbenzimidazole inhibits the reaction [Rifampin results in increased expression of CES2 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CES2 mRNA]
CTD PMID:10640517 PMID:17003103 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator multiple interactions
increases expression
ISO Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased expression of CFLAR protein modified form]]; Rifampin inhibits the reaction [FAS protein results in increased expression of CFLAR protein modified form]
Rifampin results in increased expression of CFLAR protein
CTD PMID:11958592 PMID:12645856 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CHEK2 mRNA CTD PMID:21224054 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Ciz1 CDKN1A interacting zinc finger protein 1 decreases expression ISO Rifampin results in decreased expression of CIZ1 mRNA CTD PMID:24552687 NCBI chr 3:11,392,046...11,409,218
Ensembl chr 3:11,392,791...11,410,180
JBrowse link
G Clk2 CDC-like kinase 2 decreases expression ISO Rifampin results in decreased expression of CLK2 mRNA CTD PMID:24552687 NCBI chr 2:188,476,789...188,488,809
Ensembl chr 2:188,476,820...188,496,191
JBrowse link
G Cntln centlein increases expression ISO Rifampin results in increased expression of CNTLN mRNA CTD PMID:24552687 NCBI chr 5:103,251,986...103,367,088
Ensembl chr 5:103,251,986...103,366,264
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression ISO Rifampin results in increased expression of CPT1A mRNA CTD PMID:27806127 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 decreases expression ISO Rifampin results in decreased expression of CRHR1 mRNA CTD PMID:24552687 NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645
JBrowse link
G Crp C-reactive protein multiple interactions ISO [Floxacillin co-treated with Gentamicins co-treated with Rifampin] results in increased expression of CRP protein CTD PMID:16943303 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Csnk1g1 casein kinase 1, gamma 1 decreases expression ISO Rifampin results in decreased expression of CSNK1G1 mRNA CTD PMID:24552687 NCBI chr 8:71,533,372...71,688,483
Ensembl chr 8:71,547,468...71,679,666
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression EXP Rifampin results in increased expression of CXCL1 protein CTD PMID:25051504 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions
affects expression
ISO
EXP
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CXCL10 mRNA
Rifampin affects the expression of CXCL10 protein
CTD PMID:21224054 PMID:25051504 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cyb5rl cytochrome b5 reductase-like increases expression ISO Rifampin results in increased expression of CYB5RL mRNA CTD PMID:24552687 NCBI chr 5:126,666,934...126,683,069
Ensembl chr 5:126,668,689...126,683,179
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases activity
increases expression
EXP
ISO
Rifampin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
Rifampin results in increased activity of CYP1A1 protein
Rifampin results in increased expression of CYP1A1 mRNA; Rifampin results in increased expression of CYP1A1 protein
[Methylcholanthrene co-treated with Rifampin co-treated with Phenobarbital] results in increased expression of CYP1A1 mRNA; [Rifampin co-treated with Monocrotophos] results in increased activity of CYP1A1 protein; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP1A1 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP1A1 protein; [Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of CYP1A1 mRNA; Rifampin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
CTD PMID:12040753 PMID:18493746 PMID:19118567 PMID:19409404 PMID:22733800 PMID:24999631 PMID:29162470 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
ISO
EXP
[Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of CYP1A2 mRNA; Rifampin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
Rifampin results in increased expression of CYP1A2 mRNA
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP1A2 protein
Rifampin results in increased expression of CYP1A2 mRNA; Rifampin results in increased expression of CYP1A2 protein
CTD PMID:15977188 PMID:17590308 PMID:18493746 PMID:25835148 PMID:29162470 PMID:30503582 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP1B1 mRNA
[Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of CYP1B1 mRNA
CTD PMID:21224054 PMID:29162470 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 multiple interactions
increases expression
increases activity
ISO NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP24A1 mRNA]; Rifampin promotes the reaction [NR1I2 protein binds to CYP24A1 promoter]
Rifampin results in increased activity of CYP24A1 protein
CTD PMID:15630458 PMID:21127053 NCBI chr 3:168,097,484...168,111,920
Ensembl chr 3:168,097,485...168,111,920
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP26A1 mRNA CTD PMID:21127053 NCBI chr 1:256,382,861...256,386,729
Ensembl chr 1:256,382,791...256,386,729
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO Rifampin promotes the reaction [[NR1I2 protein binds to NCOA1 protein] which binds to CYP27A1 gene]
Rifampin results in increased expression of CYP27A1 mRNA
CTD PMID:17088262 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases expression EXP Rifampin results in increased expression of CYP2A1 mRNA CTD PMID:19118567 NCBI chr 1:83,711,223...83,725,222
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 multiple interactions
increases expression
increases activity
ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP2A5 mRNA
Rifampin results in increased expression of CYP2A5 mRNA
Rifampin results in increased activity of CYP2A5 protein
CTD PMID:11038160 PMID:21224054 PMID:30503582 NCBI chr 1:83,653,248...83,662,118
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
increases expression
ISO [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2B10 protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP2B10 mRNA
Rifampin results in increased expression of CYP2B10 mRNA
CTD PMID:21224054 PMID:25835148 PMID:30503582 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
decreases expression
increases expression
increases activity
ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP2B9 mRNA
Rifampin results in decreased expression of CYP2B9 mRNA
Rifampin results in increased expression of CYP2B6 mRNA; Rifampin results in increased expression of CYP2B6 protein
[Rifampin co-treated with Monocrotophos] results in increased activity of CYP2B6 protein; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP2B6 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP2B6 protein; [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP2B6 mRNA; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of CYP2B6 mRNA; Camptothecin inhibits the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]]]; Dexamethasone promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; GW 3965 inhibits the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; NR1I2 mRNA promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; NR1I2 protein affects the reaction [Rifampin results in increased expression of and results in increased activity of CYP2B6 protein]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; Rifampin results in increased expression of and results in increased activity of CYP2B6 protein
Rifampin results in increased activity of CYP2B6 protein
CTD PMID:12040753 PMID:12571232 PMID:12695351 PMID:14709624 PMID:14977870 PMID:15548381 PMID:15629111 PMID:15802389 PMID:16608920 PMID:17041008 PMID:17438109 PMID:17954527 PMID:18094037 PMID:18332078 PMID:19118567 PMID:19202563 PMID:19497361 PMID:20035023 PMID:20361990 PMID:21224054 PMID:21315811 PMID:22126990 PMID:22258563 PMID:22524704 PMID:22733800 PMID:23732298 PMID:24038852 PMID:24259679 PMID:24552687 PMID:25313206 PMID:25929522 PMID:26196221 PMID:27871908 PMID:27917125 PMID:28289823 PMID:28887089 PMID:29356861 PMID:30071242 PMID:30503582 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 increases activity
multiple interactions
increases expression
ISO Rifampin results in increased activity of CYP2C9 protein
Ketoconazole inhibits the reaction [Rifampin results in increased expression of CYP2C9 mRNA]; NCOA6 promotes the reaction [Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]]; NR1I2 protein affects the reaction [Rifampin results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NCOA6] results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP2C9 mRNA]; Rifampin results in increased activity of and results in increased expression of CYP2C9 protein; Rifampin results in increased expression of and results in increased activity of CYP2C9 protein
Rifampin results in increased expression of CYP2C9 mRNA; Rifampin results in increased expression of CYP2C9 protein
CTD PMID:14600250 PMID:14709624 PMID:14722322 PMID:15629111 PMID:15802389 PMID:15919766 PMID:16267138 PMID:16608920 PMID:17590308 PMID:17954527 PMID:19041297 PMID:19118567 PMID:19202563 PMID:19497360 PMID:19686824 PMID:21292004 PMID:22126990 PMID:22843569 PMID:24259679 PMID:24552687 PMID:24830941 PMID:25929522 PMID:26196221 PMID:27590069 PMID:27794450 PMID:27917125 PMID:28887089 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 decreases expression ISO Rifampin results in decreased expression of CYP2C18 mRNA; Rifampin results in decreased expression of CYP2C18 protein CTD PMID:22258563 PMID:31629065 NCBI chr 1:258,074,797...258,139,176
Ensembl chr 1:258,074,860...258,139,176
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 increases activity
increases expression
multiple interactions
ISO Rifampin results in increased activity of CYP2C19 protein
Rifampin results in increased expression of CYP2C19 mRNA; Rifampin results in increased expression of CYP2C19 protein
Rifampin results in increased expression of and results in increased activity of CYP2C19 protein
CTD PMID:12584154 PMID:14709624 PMID:15629111 PMID:17954527 PMID:19118567 PMID:22126990 PMID:22310298 PMID:24552687 PMID:24830941 PMID:27917125 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 affects binding
increases expression
multiple interactions
increases activity
ISO [Rifampin binds to NR1I2 protein] which binds to CYP2C8 promoter
Rifampin results in increased expression of CYP2C29 mRNA
[Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of BCL2 protein; [Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of MCL1 protein; [Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in increased expression of BAX protein; Camptothecin inhibits the reaction [Rifampin results in increased expression of CYP2C8 mRNA]; pimecrolimus inhibits the reaction [Rifampin results in increased expression of CYP2C8 mRNA]; Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2C protein
Rifampin results in increased expression of CYP2C8 mRNA; Rifampin results in increased expression of CYP2C8 protein
Rifampin results in increased activity of CYP2C8 protein
CTD PMID:12040753 PMID:15771232 PMID:15933212 PMID:17954527 PMID:19118567 PMID:22126990 PMID:25313206 PMID:25835148 PMID:29356861 PMID:30503582 PMID:31629065 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases expression
decreases expression
ISO Rifampin results in increased expression of CYP2D6 mRNA
Rifampin results in decreased expression of CYP2D22 mRNA
CTD PMID:19041851 PMID:30503582 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases activity
decreases expression
multiple interactions
increases expression
ISO
EXP
Rifampin results in increased activity of CYP2E1 protein
Rifampin results in decreased expression of CYP2E1 mRNA
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP2E1 protein
Rifampin results in increased expression of CYP2E1 mRNA; Rifampin results in increased expression of CYP2E1 protein
[Rifampin co-treated with Monocrotophos] results in increased activity of CYP2E1 protein; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP2E1 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP2E1 protein
[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein; [Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA; [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]; [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]; Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]; Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]; Rifampin inhibits the reaction [Isoniazid results in increased expression of CYP2E1 protein]
CTD PMID:15132840 PMID:18071298 PMID:22258563 PMID:22733800 PMID:25835148 PMID:27919644 PMID:30503582 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 decreases expression ISO Rifampin results in decreased expression of CYP2F1 mRNA CTD PMID:22258563 NCBI chr 1:83,933,974...83,947,804
Ensembl chr 1:83,933,942...83,947,821
JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP2S1 mRNA CTD PMID:21127053 NCBI chr 1:82,595,211...82,610,350
Ensembl chr 1:82,595,211...82,610,350
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases expression
EXP [Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP3A2 mRNA; [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP3A2 mRNA]; arsenite inhibits the reaction [Rifampin results in increased expression of and results in increased activity of CYP3A2 protein]; arsenite inhibits the reaction [Rifampin results in increased expression of CYP3A2 mRNA]; Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP3A2 mRNA]; Rifampin results in increased expression of and results in increased activity of CYP3A2 protein CTD PMID:22159698 PMID:27919644 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 multiple interactions
increases expression
EXP [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A23-3A1 mRNA; arsenite inhibits the reaction [Rifampin results in increased expression of and results in increased activity of CYP3A23-3A1 protein]; arsenite inhibits the reaction [Rifampin results in increased expression of CYP3A23-3A1 mRNA]; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to CYP3A23-3A1 promoter]; Rifampin results in increased expression of and results in increased activity of CYP3A23-3A1 protein; sodium arsenite inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A23-3A1 mRNA] CTD PMID:12370413 PMID:19041297 PMID:22159698 PMID:22310326 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 multiple interactions
increases expression
increases activity
decreases response to substance
affects activity
ISO
EXP
[Dimethyl Sulfoxide results in increased susceptibility to Rifampin] which results in increased expression of CYP3A4 mRNA; [HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; [Methylcholanthrene co-treated with Rifampin co-treated with Phenobarbital] results in increased expression of CYP3A4 mRNA; [NR1I2 protein binds to NCOR2 protein] inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; [NR1I2 protein co-treated with Rifampin] results in decreased expression of CYP3A4 mRNA; [PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; [Rifampin binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; [Rifampin binds to CYP3A4 promoter] which results in increased expression of CYP3A4 mRNA; [Rifampin co-treated with Monocrotophos] results in increased activity of CYP3A4 protein; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP3A4 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP3A4 protein; [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; [Rifampin results in increased expression of CYP3A4 protein] which results in decreased abundance of Ethinyl Estradiol; [Rifampin results in increased expression of CYP3A4 protein] which results in decreased abundance of Midazolam; [Rifampin results in increased expression of CYP3A4 protein] which results in increased hydroxylation of Testosterone; [Rifampin results in increased expression of NR1I2 protein] which results in increased expression of and results in increased activity of CYP3A4 protein; [RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; [SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; [Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; AADAC mRNA affects the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [Rifampin results in increased activity of CYP3A4 protein]; allyl isothiocyanate inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [Rifampin results in increased expression of CYP3A4 protein]; Arsenic Trioxide inhibits the reaction [Rifampin results in increased expression of CYP3A4 protein]; Calcitriol promotes the reaction [Rifampin results in increased activity of CYP3A4 protein]; Calcitriol promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Camptothecin inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; CYP3A4 protein inhibits the reaction [Rifampin results in decreased chemical synthesis of 1-hydroxymethylmidazolam]; CYP3A4 protein inhibits the reaction [Rifampin results in decreased chemical synthesis of 4-hydroxymidazolam]; CYP3A4 protein inhibits the reaction [Rifampin results in decreased hydroxylation of Midazolam]; Dexamethasone promotes the reaction [Rifampin results in increased activity of CYP3A4 protein]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Econazole promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Galactosamine inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; GW 3965 inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]]; Ketoconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [Rifampin results in increased activity of CYP3A4 protein]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of CYP3A4 protein]; Metformin inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Metformin inhibits the reaction [Rifampin results in increased expression of CYP3A4 protein]; N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]; NR1H3 mutant form inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; NR1I2 gene promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]; NR1I2 mRNA promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; NR1I2 protein affects the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; NR1I2 protein affects the reaction [Rifampin results in increased expression of CYP3A4 protein]; NR1I2 protein inhibits the reaction [Thapsigargin inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]; NR3C1 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; ochratoxin A inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; ochratoxin A inhibits the reaction [Rifampin results in increased expression of CYP3A4 protein]; oxiconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; PRMT1 protein affects the reaction [[Dimethyl Sulfoxide results in increased susceptibility to Rifampin] which results in increased expression of CYP3A4 mRNA]; PRMT1 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; PRMT1 protein affects the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Rifampin binds to and results in increased activity of CYP3A4 protein; Rifampin inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 1-hydroxymethylmidazolam]; Rifampin inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 4-hydroxymidazolam]; Rifampin inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Rifampin promotes the reaction [[HNF4A co-treated with NCOA6] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [[NCOA1 protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [Calcitriol results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [CYP3A4 protein results in increased chemical synthesis of 1-hydroxymethylmidazolam]; Rifampin promotes the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Rifampin promotes the reaction [CYP3A4 protein results in increased metabolism of Lidocaine]; Rifampin promotes the reaction [NR1I2 protein binds to CYP3A4 promoter]; Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]; Rifampin results in increased expression of and results in increased activity of CYP3A4 protein; Skatole inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Skatole inhibits the reaction [Rifampin results in increased expression of CYP3A4 protein]; sodium arsenite inhibits the reaction [Rifampin results in increased expression of and results in increased activity of CYP3A4 protein]; sodium arsenite inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; sulforafan inhibits the reaction [Rifampin results in increased expression of CYP3A4]; Tetrachlorodibenzodioxin inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [Rifampin results in increased expression of CYP3A4 protein]; Thapsigargin inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; trichostatin A affects the reaction [Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; trichostatin A promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP3A11 protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP3A11 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP3A4 protein; [Rifampin binds to NR1I2 gene mutant form] which results in increased expression of CYP3A11 mRNA; NR1I2 affects the reaction [Rifampin results in increased activity of CYP3A4 protein]; sulforafan inhibits the reaction [Rifampin results in increased expression of CYP3A11 mRNA]
Rifampin results in increased expression of CYP3A11 mRNA; Rifampin results in increased expression of CYP3A11 protein
CYP3A4 protein results in decreased susceptibility to Rifampin
Rifampin affects the activity of CYP3A4 protein
Rifampin results in increased expression of CYP3A4; Rifampin results in increased expression of CYP3A4 mRNA; Rifampin results in increased expression of CYP3A4 mRNA alternative form; Rifampin results in increased expression of CYP3A4 protein
CTD PMID:8632764 PMID:9298257 PMID:9512926 PMID:10219967 PMID:10640517 PMID:10859152 PMID:11581012 PMID:12040753 PMID:12065438 PMID:12072427 PMID:12235278 PMID:12417264 PMID:12505310 PMID:12584154 PMID:12642470 PMID:12673034 PMID:12695340 PMID:12695342 PMID:12851153 PMID:14600250 PMID:14636322 PMID:14709624 PMID:14722322 PMID:14977870 PMID:15075359 PMID:15466163 PMID:15548381 PMID:15554232 PMID:15629111 PMID:15681896 PMID:15710169 PMID:15769886 PMID:15771232 PMID:15802389 PMID:15833926 PMID:15855724 PMID:15964336 PMID:15977188 PMID:16146350 PMID:16184197 PMID:16565514 PMID:16608920 PMID:16632523 PMID:16819505 PMID:16837568 PMID:17003103 PMID:17041008 PMID:17270371 PMID:17293382 PMID:17438109 PMID:17590308 PMID:17936189 PMID:17954527 PMID:17998298 PMID:18094037 PMID:18332045 PMID:18332078 PMID:18505790 PMID:18799805 PMID:18839173 PMID:19041297 PMID:19118567 PMID:19135037 PMID:19202563 PMID:19230594 PMID:19686824 PMID:19854261 PMID:20035023 PMID:20035846 PMID:20233841 PMID:20361990 PMID:20599501 PMID:20869979 PMID:21127053 PMID:21224054 PMID:21292004 PMID:21315811 PMID:21402137 PMID:21641981 PMID:21742782 PMID:21764778 PMID:21856291 PMID:21920351 PMID:21924250 PMID:21998292 PMID:22093699 PMID:22126990 PMID:22178124 PMID:22258563 PMID:22310298 PMID:22310326 PMID:22314385 PMID:22467028 PMID:22524704 PMID:22664347 PMID:22687401 PMID:22733800 PMID:22843569 PMID:22982774 PMID:23153560 PMID:23707768 PMID:23732298 PMID:23845848 PMID:23850985 PMID:23899473 PMID:24038852 PMID:24146111 PMID:24204015 PMID:24259679 PMID:24552687 PMID:24685772 PMID:24752503 PMID:24999631 PMID:25069801 PMID:25084468 PMID:25313206 PMID:25455453 PMID:25512232 PMID:25542144 PMID:25616597 PMID:25835148 PMID:25929522 PMID:26196221 PMID:26201057 PMID:26301745 PMID:26341324 PMID:26616219 PMID:27177772 PMID:27180241 PMID:27507784 PMID:27590069 PMID:27794450 PMID:27806127 PMID:27871908 PMID:27917125 PMID:28289823 PMID:28571685 PMID:28887089 PMID:28916285 PMID:29162470 PMID:29356861 PMID:29933105 PMID:30071242 PMID:30087611 PMID:30503582 PMID:31132328 PMID:31233785 PMID:31870919 PMID:31877331 PMID:32092453 PMID:32682830 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression ISO Rifampin results in increased expression of CYP3A5 mRNA CTD PMID:12040753 PMID:12673034 PMID:15629111 PMID:15681896 PMID:19118567 PMID:20832446 PMID:24146111 PMID:24259679 PMID:28496040 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions
decreases expression
ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP7A1 mRNA
Rifampin results in decreased expression of CYP7A1 mRNA
NR1I2 protein promotes the reaction [Rifampin results in decreased expression of CYP7A1 mRNA]
CTD PMID:15629111 PMID:21127053 PMID:21224054 PMID:22258563 PMID:24259679 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in decreased expression of CYP8B1 mRNA CTD PMID:21127053 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
JBrowse link
G Dcaf5 DDB1 and CUL4 associated factor 5 decreases expression ISO Rifampin results in decreased expression of DCAF5 mRNA CTD PMID:24552687 NCBI chr 6:103,516,586...103,605,288
Ensembl chr 6:103,516,586...103,605,256
JBrowse link
G Dclre1b DNA cross-link repair 1B decreases expression ISO Rifampin results in decreased expression of DCLRE1B mRNA CTD PMID:24552687 NCBI chr 2:206,285,085...206,293,599
Ensembl chr 2:206,285,089...206,293,599
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of DDIT3 mRNA
4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of DDIT3 mRNA]
Rifampin results in increased expression of DDIT3 mRNA; Rifampin results in increased expression of DDIT3 protein
CTD PMID:21224054 PMID:27470132 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase multiple interactions ISO [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of DHCR24 mRNA CTD PMID:22101211 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
G Dio1 iodothyronine deiodinase 1 increases expression ISO Rifampin results in increased expression of DIO1 mRNA CTD PMID:24552687 NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520
JBrowse link
G Dlx4 distal-less homeobox 4 decreases expression ISO Rifampin results in decreased expression of DLX4 mRNA CTD PMID:24552687 NCBI chr10:82,958,525...82,963,919
Ensembl chr10:82,958,525...82,963,919
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of DNAJA1 mRNA CTD PMID:21224054 NCBI chr 5:57,028,467...57,039,378
Ensembl chr 5:57,028,467...57,039,378
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of E2F1 mRNA CTD PMID:21224054 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of EDN1 mRNA CTD PMID:21127053 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of EGR1 mRNA
[Rifampin co-treated with NR1I2 protein] results in increased expression of EGR1 mRNA
CTD PMID:21127053 PMID:21224054 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Egr2 early growth response 2 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of EGR2 mRNA CTD PMID:21127053 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Egr4 early growth response 4 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of EGR4 mRNA CTD PMID:21127053 NCBI chr 4:117,293,620...117,296,082
Ensembl chr 4:117,293,620...117,296,082
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation
increases expression
multiple interactions
EXP
ISO
Rifampin results in increased phosphorylation of EIF2AK3 protein
Rifampin results in increased expression of EIF2AK3 mRNA; Rifampin results in increased expression of EIF2AK3 protein
4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of EIF2AK3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of EIF2AK3 protein]
CTD PMID:24638036 PMID:27470132 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation EXP Rifampin results in increased phosphorylation of EIF2S1 protein CTD PMID:24638036 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Elk1 ETS transcription factor ELK1 decreases expression ISO Rifampin results in decreased expression of ELK1 mRNA CTD PMID:24552687 NCBI chr  X:1,287,875...1,304,822
Ensembl chr  X:1,297,099...1,304,822
JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of EPAS1 mRNA CTD PMID:21127053 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression
multiple interactions
ISO Rifampin results in increased expression of EPHX1 mRNA
pimecrolimus inhibits the reaction [Rifampin results in increased expression of EPHX1 mRNA]
CTD PMID:22258563 PMID:25313206 PMID:29356861 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Etnppl ethanolamine-phosphate phospho-lyase increases expression ISO Rifampin results in increased expression of ETNPPL mRNA CTD PMID:24552687 NCBI chr 2:235,738,377...235,760,351
Ensembl chr 2:235,738,416...235,760,352
JBrowse link
G F13b coagulation factor XIII B chain increases expression ISO Rifampin results in increased expression of F13B mRNA CTD PMID:24552687 NCBI chr13:56,598,891...56,623,132
Ensembl chr13:56,598,957...56,623,124
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased activity of CASP3 protein]]; Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased activity of CASP8 protein]]; Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased expression of CFLAR protein modified form]]; Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased expression of FASLG protein]]; Rifampin inhibits the reaction [FAS protein results in increased activity of CASP3 protein]; Rifampin inhibits the reaction [FAS protein results in increased activity of CASP8 protein]; Rifampin inhibits the reaction [FAS protein results in increased expression of CFLAR protein modified form]; Rifampin inhibits the reaction [FAS protein results in increased expression of FASLG protein] CTD PMID:11958592 PMID:12645856 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand multiple interactions
decreases expression
ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FASL mRNA
Rifampin results in decreased expression of FASLG mRNA; Rifampin results in decreased expression of FASLG protein
Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased expression of FASLG protein]]; Rifampin inhibits the reaction [FAS protein results in increased expression of FASLG protein]
CTD PMID:11958592 PMID:12645856 PMID:21224054 PMID:24552687 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fasn fatty acid synthase increases expression
multiple interactions
ISO Rifampin results in increased expression of FASN mRNA
pimecrolimus inhibits the reaction [Rifampin results in increased expression of FASN mRNA]
CTD PMID:27806127 PMID:29356861 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fgf19 fibroblast growth factor 19 multiple interactions
increases expression
ISO [Rifampin binds to and results in increased activity of NR1I2 protein] which results in increased expression of FGF19 mRNA
Rifampin results in increased expression of FGF19 mRNA
CTD PMID:17696253 NCBI chr 1:218,058,405...218,061,693
Ensembl chr 1:218,058,405...218,061,693
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FMO1 mRNA CTD PMID:21224054 NCBI chr13:80,712,885...80,745,095
Ensembl chr13:80,712,882...80,745,347
JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FMO4 mRNA CTD PMID:21224054 NCBI chr13:80,685,385...80,703,575
Ensembl chr13:80,685,325...80,703,615
JBrowse link
G Foxa1 forkhead box A1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in decreased expression of FOXA1 mRNA CTD PMID:21127053 NCBI chr 6:78,516,579...78,549,669
Ensembl chr 6:78,545,804...78,549,669
JBrowse link
G Foxp1 forkhead box P1 increases expression ISO Rifampin results in increased expression of FOXP1 mRNA CTD PMID:24552687 NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755
JBrowse link
G Fut1 fucosyltransferase 1 decreases expression ISO Rifampin results in decreased expression of FUT1 mRNA CTD PMID:24552687 NCBI chr 1:101,599,018...101,602,440
Ensembl chr 1:101,599,018...101,602,436
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions
affects expression
ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA; INS protein inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA]; SGK2 mutant form affects the reaction [Rifampin affects the expression of G6PC1 mRNA]; SGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA] CTD PMID:24204015 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GADD45A mRNA CTD PMID:21224054 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta multiple interactions ISO NR1I2 protein promotes the reaction [Rifampin results in increased expression of GADD45B mRNA] CTD PMID:21127053 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322
JBrowse link
G Gata5 GATA binding protein 5 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in decreased expression of GATA5 mRNA CTD PMID:21127053 NCBI chr 3:175,701,278...175,709,465
Ensembl chr 3:175,701,280...175,709,465
JBrowse link
G Gck glucokinase decreases expression
multiple interactions
ISO Rifampin results in decreased expression of GCK protein
NR1I2 protein promotes the reaction [Rifampin results in decreased expression of GCK protein]
CTD PMID:26616219 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Glis2 GLIS family zinc finger 2 increases expression ISO Rifampin results in increased expression of GLIS2 mRNA CTD PMID:24552687 NCBI chr10:11,154,459...11,177,063
Ensembl chr10:11,154,658...11,174,861
JBrowse link
G Gnal G protein subunit alpha L decreases expression ISO Rifampin results in decreased expression of GNAL mRNA CTD PMID:24552687 NCBI chr18:62,805,406...62,946,133
Ensembl chr18:62,805,410...62,944,630
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases expression
ISO 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of GPT protein]; [Rifampin co-treated with Acetaminophen] results in decreased activity of GPT protein
Rifampin inhibits the reaction [Acetaminophen results in increased expression of GPT protein]
CTD PMID:24685772 PMID:27470132 PMID:31678598 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GPX2 mRNA CTD PMID:21224054 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 decreases expression ISO Rifampin results in decreased expression of GRIA1 mRNA CTD PMID:24552687 NCBI chr10:42,441,723...42,760,200
Ensembl chr10:42,614,713...42,760,200
JBrowse link
G Gsr glutathione-disulfide reductase increases activity ISO Rifampin results in increased activity of GSR protein CTD PMID:20848779 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions
increases expression
ISO [Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of GSTA1 mRNA; Ketoconazole inhibits the reaction [Rifampin results in increased expression of GSTA1 mRNA] CTD PMID:16608920 PMID:19118567 PMID:29162470 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM1 protein CTD PMID:21224054 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM3 mRNA CTD PMID:21224054 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
increases expression
ISO [Rifampin co-treated with Monocrotophos] results in increased expression of GSTP1 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of GSTP1 protein
Rifampin results in increased expression of GSTP1 mRNA; Rifampin results in increased expression of GSTP1 protein
CTD PMID:22733800 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gstt1 glutathione S-transferase theta 1 multiple interactions ISO GSTT1 gene polymorphism affects the susceptibility to [Isoniazid co-treated with Rifampin]; GSTT1 gene polymorphism results in increased susceptibility to [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide] CTD PMID:18397238 PMID:20485159 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Gtf2ird2 GTF2I repeat domain containing 2 increases expression ISO Rifampin results in increased expression of GTF2IRD2 mRNA CTD PMID:24552687 NCBI chr12:25,509,059...25,555,554
Ensembl chr12:25,509,653...25,546,200
JBrowse link
G Gzmb granzyme B increases secretion ISO Rifampin results in increased secretion of GZMB protein CTD PMID:27933861 NCBI chr15:35,413,862...35,417,293
Ensembl chr15:35,413,793...35,417,316
JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of HBEGF mRNA CTD PMID:21127053 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Hdac3 histone deacetylase 3 multiple interactions ISO Rifampin inhibits the reaction [trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]] CTD PMID:26883953 NCBI chr18:31,073,057...31,094,347
Ensembl chr18:31,073,058...31,094,303
JBrowse link
G Hdac5 histone deacetylase 5 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in decreased expression of HDAC5 mRNA CTD PMID:21127053 NCBI chr10:90,140,183...90,169,853
Ensembl chr10:90,140,183...90,151,042
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of HEY1 mRNA CTD PMID:21127053 NCBI chr 2:95,320,147...95,322,701
Ensembl chr 2:95,320,283...95,322,696
JBrowse link
G Hgf hepatocyte growth factor multiple interactions ISO HGF protein inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased abundance of Reactive Oxygen Species]; HGF protein inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased activity of CASP3 protein] CTD PMID:23764483 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of HIF1A mRNA CTD PMID:21127053 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmgn5 high mobility group nucleosome binding domain 5 increases expression ISO Rifampin results in increased expression of HMGN5 mRNA CTD PMID:24552687 NCBI chr  X:80,134,557...80,142,902
Ensembl chr  X:80,134,557...80,142,902
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO
EXP
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HMOX1 mRNA
dorsomorphin inhibits the reaction [Rifampin results in increased expression of HMOX1 protein]
Rifampin results in increased expression of HMOX1 mRNA; Rifampin results in increased expression of HMOX1 protein
[arsenite co-treated with Rifampin] results in increased expression of HMOX1 mRNA
CTD PMID:21224054 PMID:22159698 PMID:22258563 PMID:31678598 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha multiple interactions ISO [HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of HNF4A mRNA; [Rifampin results in increased activity of NR1I2 protein] inhibits the reaction [HNF4A protein binds to SULT1E1 enhancer]; allyl isothiocyanate inhibits the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; NCOA6 promotes the reaction [Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]]; NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; Rifampin inhibits the reaction [HNF4A protein binds to SULT1E1 enhancer]; Rifampin promotes the reaction [[HNF4A co-treated with NCOA6] results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NCOA6] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [MED1 protein binds to HNF4A protein]; Rifampin promotes the reaction [NCOA1 protein binds to HNF4A protein]; Rifampin promotes the reaction [NCOA2 protein binds to HNF4A protein]; Rifampin promotes the reaction [NCOA6 protein binds to HNF4A protein]; Rifampin promotes the reaction [NR1I2 protein binds to HNF4A protein]; Rifampin promotes the reaction [PPARGC1A protein binds to HNF4A protein] CTD PMID:21127053 PMID:21292004 PMID:21764778 PMID:25069801 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Hrh1 histamine receptor H 1 increases expression ISO Rifampin results in increased expression of HRH1 mRNA CTD PMID:24552687 NCBI chr 4:146,374,596...146,458,148
Ensembl chr 4:146,455,332...146,457,074
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPA1L mRNA CTD PMID:21224054 NCBI chr20:4,879,998...4,965,191
Ensembl chr20:4,959,294...4,964,963
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression
EXP
ISO
ATF4 mutant form inhibits the reaction [Rifampin results in increased expression of HSPA5 protein]
4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of HSPA5 protein]
Rifampin results in increased expression of HSPA5 mRNA; Rifampin results in increased expression of HSPA5 protein
CTD PMID:24638036 PMID:27470132 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPA8 mRNA CTD PMID:21224054 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPB1 mRNA CTD PMID:21224054 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of HSPD1 mRNA CTD PMID:21224054 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of HSPE1 mRNA CTD PMID:21224054 NCBI chr 9:61,691,246...61,724,948
Ensembl chr 9:61,692,154...61,694,599
JBrowse link
G Ifng interferon gamma increases secretion ISO Rifampin results in increased secretion of IFNG protein CTD PMID:27933861 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP1 mRNA CTD PMID:21127053 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP3 mRNA CTD PMID:21127053 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP4 mRNA CTD PMID:21127053 NCBI chr10:86,950,555...86,962,563
Ensembl chr10:86,950,557...86,962,578
JBrowse link
G Il10 interleukin 10 affects expression EXP Rifampin affects the expression of IL10 protein CTD PMID:25051504 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12rb2 interleukin 12 receptor subunit beta 2 decreases expression ISO Rifampin results in decreased expression of IL12RB2 mRNA CTD PMID:24552687 NCBI chr 4:98,049,195...98,141,562
Ensembl chr 4:98,052,842...98,141,482
JBrowse link
G Il13 interleukin 13 increases secretion ISO Rifampin results in increased secretion of IL13 protein CTD PMID:27933861 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il18 interleukin 18 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL18 mRNA CTD PMID:21224054 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
ISO
EXP
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL1B mRNA; Rifampin inhibits the reaction [Rotenone results in increased expression of and results in increased secretion of IL1B protein]; Rifampin inhibits the reaction [Rotenone results in increased expression of IL1B mRNA]
Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased expression of IL1B mRNA]]; Rifampin inhibits the reaction [Rotenone results in increased expression of IL1B mRNA]
Rifampin results in decreased expression of IL1B mRNA; Rifampin results in decreased expression of IL1B protein
CTD PMID:21224054 PMID:25051504 PMID:26086368 PMID:31648047 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions
increases expression
ISO
EXP
Rifampin results in decreased expression of IL6 protein
Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased expression of IL6 mRNA]]; Rifampin inhibits the reaction [Rotenone results in increased expression of IL6 mRNA]
Rifampin results in increased expression of IL6 protein
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of IL6 mRNA
CTD PMID:21224054 PMID:21357946 PMID:25051504 PMID:31648047 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ino80d INO80 complex subunit D decreases expression ISO Rifampin results in decreased expression of INO80D mRNA CTD PMID:24552687 NCBI chr 9:69,820,520...69,887,475
Ensembl chr 9:69,830,424...69,878,706
JBrowse link
G Ins2 insulin 2 multiple interactions ISO INS protein inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA] CTD PMID:24204015 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Ints6 integrator complex subunit 6 decreases expression ISO Rifampin results in decreased expression of INTS6 mRNA CTD PMID:24552687 NCBI chr15:45,844,050...45,929,996
Ensembl chr15:45,858,608...45,947,030
JBrowse link
G Iqca1 IQ motif containing with AAA domain 1 decreases expression ISO Rifampin results in decreased expression of IQCA1 mRNA CTD PMID:24552687 NCBI chr 9:97,190,240...97,298,760 JBrowse link
G Itgbl1 integrin subunit beta like 1 decreases expression ISO Rifampin results in decreased expression of ITGBL1 mRNA CTD PMID:24552687 NCBI chr15:110,114,148...110,378,970
Ensembl chr15:110,114,148...110,378,969
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of JUN mRNA CTD PMID:21127053 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kirrel3 kirre like nephrin family adhesion molecule 3 decreases expression ISO Rifampin results in decreased expression of KIRREL3 mRNA CTD PMID:24552687 NCBI chr 8:35,692,525...36,254,755
Ensembl chr 8:36,125,999...36,254,753
JBrowse link
G Klf2 Kruppel-like factor 2 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF2 mRNA CTD PMID:21127053 NCBI chr16:19,223,087...19,225,037
Ensembl chr16:19,223,087...19,225,037
JBrowse link
G Klf5 Kruppel-like factor 5 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF5 mRNA CTD PMID:21127053 NCBI chr15:83,703,796...83,722,921
Ensembl chr15:83,703,791...83,722,921
JBrowse link
G Klf6 Kruppel-like factor 6 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF6 mRNA CTD PMID:21127053 NCBI chr17:67,887,939...67,945,052
Ensembl chr17:67,887,939...67,945,037
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO Rifampin results in increased expression of LDLR mRNA CTD PMID:27806127 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Lefty1 left right determination factor 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of LEFTY1 mRNA CTD PMID:21127053 NCBI chr13:99,212,778...99,217,786
Ensembl chr13:99,214,389...99,217,786
JBrowse link
G Lep leptin increases expression EXP Rifampin results in increased expression of LEP protein CTD PMID:25051504 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G LOC100910107 ubiquitin carboxyl-terminal hydrolase DUB-1-like decreases expression ISO Rifampin results in decreased expression of USP17L2 mRNA CTD PMID:24552687 NCBI chr 1:169,720,247...169,721,788
Ensembl chr 1:169,720,253...169,721,758
JBrowse link
G LOC100912252 uncharacterized LOC100912252 decreases expression ISO Rifampin results in decreased expression of C9ORF153 mRNA CTD PMID:24552687 NCBI chr17:5,353,600...5,360,735
Ensembl chr17:5,353,622...5,360,553
JBrowse link
G LOC498933 LOC498933 decreases expression ISO Rifampin results in decreased expression of C4ORF51 mRNA CTD PMID:24552687 NCBI chr19:32,344,078...32,380,029
Ensembl chr19:32,344,078...32,380,025
JBrowse link
G Ltk leukocyte receptor tyrosine kinase increases expression ISO Rifampin results in increased expression of LTK mRNA CTD PMID:24552687 NCBI chr 3:111,553,679...111,560,556
Ensembl chr 3:111,553,680...111,560,556
JBrowse link
G Maff MAF bZIP transcription factor F multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of MAFF mRNA CTD PMID:21127053 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta decreases metabolic processing
multiple interactions
increases lipidation
ISO Rifampin results in decreased metabolism of MAP1LC3B protein
ATP6V0D1 protein affects the reaction [Rifampin inhibits the reaction [Rotenone results in increased lipidation of MAP1LC3B protein]]; Chloroquine promotes the reaction [Rifampin results in increased lipidation of MAP1LC3B protein]; Rifampin inhibits the reaction [Rotenone results in increased lipidation of MAP1LC3B protein]
CTD PMID:29908302 PMID:31648047 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein]]; Rifampin inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein] CTD PMID:31648047 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 increases phosphorylation ISO Rifampin results in increased phosphorylation of MAPKAPK2 protein CTD PMID:21127053 NCBI chr13:47,785,157...47,871,684
Ensembl chr13:47,785,161...47,831,110
JBrowse link
G Mapre3 microtubule-associated protein, RP/EB family, member 3 increases expression ISO Rifampin results in increased expression of MAPRE3 mRNA CTD PMID:24552687 NCBI chr 6:26,878,738...26,923,459
Ensembl chr 6:26,878,744...26,889,882
JBrowse link
G Matn2 matrilin 2 increases expression ISO Rifampin results in increased expression of MATN2 mRNA CTD PMID:27177772 NCBI chr 7:72,985,832...73,210,093
Ensembl chr 7:72,985,495...73,207,695
JBrowse link
G Mbp myelin basic protein affects expression EXP Rifampin affects the expression of MBP mRNA CTD PMID:22954530 NCBI chr18:79,326,738...79,437,310
Ensembl chr18:79,326,738...79,437,310
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions ISO [Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of MCL1 protein CTD PMID:31629065 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of MDM2 mRNA CTD PMID:21224054 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Med1 mediator complex subunit 1 multiple interactions
decreases expression
ISO Rifampin promotes the reaction [MED1 protein binds to and results in increased activity of NR1I2 protein]; Rifampin promotes the reaction [MED1 protein binds to HNF4A protein]
Rifampin results in decreased expression of MED1 mRNA
CTD PMID:21292004 PMID:22214767 PMID:24552687 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
JBrowse link
G Minpp1 multiple inositol-polyphosphate phosphatase 1 increases expression ISO Rifampin results in increased expression of MINPP1 mRNA CTD PMID:24552687 NCBI chr 1:251,045,352...251,071,045
Ensembl chr 1:251,045,440...251,071,040
JBrowse link
G Mir143 microRNA 143 increases expression ISO Rifampin results in increased expression of MIR143 mRNA CTD PMID:24552687 NCBI chr18:56,971,273...56,971,377
Ensembl chr18:56,971,273...56,971,377
JBrowse link
G Mir145 microRNA 145 increases expression ISO Rifampin results in increased expression of MIR145 mRNA CTD PMID:24552687 NCBI chr18:56,969,907...56,969,994
Ensembl chr18:56,969,907...56,969,994
JBrowse link
G Mir148b microRNA 148b decreases expression ISO Rifampin results in decreased expression of MIR148B mRNA CTD PMID:24552687 NCBI chr 7:144,912,038...144,912,134
Ensembl chr 7:144,912,038...144,912,134
JBrowse link
G Mir15b microRNA 15b increases expression ISO Rifampin results in increased expression of MIR15B mRNA CTD PMID:24552687 NCBI chr 2:165,605,923...165,606,020
Ensembl chr 2:165,605,923...165,606,020
JBrowse link
G Mir192 microRNA 192 decreases expression ISO Rifampin results in decreased expression of MIR192 mRNA CTD PMID:24552687 NCBI chr 1:221,634,971...221,635,080
Ensembl chr 1:221,634,971...221,635,080
JBrowse link
G Mir200a microRNA 200a increases expression ISO Rifampin results in increased expression of MIR200A mRNA CTD PMID:24552687 NCBI chr 5:173,489,366...173,489,454 JBrowse link
G Mir202 microRNA 202 increases expression ISO Rifampin results in increased expression of MIR202 mRNA CTD PMID:24552687 NCBI chr 1:212,295,630...212,295,701
Ensembl chr 1:212,295,630...212,295,701
JBrowse link
G Mir204 microRNA 204 increases expression ISO Rifampin results in increased expression of MIR204 mRNA CTD PMID:24552687 NCBI chr 1:240,403,000...240,403,109
Ensembl chr 1:240,403,000...240,403,109
JBrowse link
G Mir20b microRNA 20b increases expression ISO Rifampin results in increased expression of MIR20B mRNA CTD PMID:24552687 NCBI chr  X:140,117,518...140,117,589
Ensembl chr  X:140,117,518...140,117,589
JBrowse link
G Mir21 microRNA 21 increases expression ISO Rifampin results in increased expression of MIR21 mRNA CTD PMID:24552687 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mir212 microRNA 212 decreases expression ISO Rifampin results in decreased expression of MIR212 mRNA CTD PMID:24552687 NCBI chr10:62,014,702...62,014,812
Ensembl chr10:62,014,702...62,014,812
JBrowse link
G Mir22 microRNA 22 increases expression ISO Rifampin results in increased expression of MIR22 mRNA CTD PMID:24552687 NCBI chr10:62,299,592...62,299,686
Ensembl chr10:62,299,592...62,299,686
JBrowse link
G Mir26b microRNA 26b increases expression ISO Rifampin results in increased expression of MIR26B mRNA CTD PMID:24552687 NCBI chr 9:81,675,275...81,675,359
Ensembl chr 9:81,675,275...81,675,359
JBrowse link
G Mir296 microRNA 296 decreases expression ISO Rifampin results in decreased expression of MIR296 mRNA CTD PMID:24552687 NCBI chr 3:172,357,490...172,357,567
Ensembl chr 3:172,357,490...172,357,567
JBrowse link
G Mir29a microRNA 29a decreases expression ISO Rifampin results in decreased expression of MIR29A mRNA CTD PMID:24552687 NCBI chr 4:58,343,931...58,344,018 JBrowse link
G Mir31 microRNA 31 increases expression ISO Rifampin results in increased expression of MIR31 mRNA CTD PMID:24552687 NCBI chr 5:107,206,515...107,206,620 JBrowse link
G Mir328 microRNA 328 increases expression ISO Rifampin results in increased expression of MIR328 mRNA CTD PMID:24552687 NCBI chr19:37,263,199...37,263,282
Ensembl chr19:37,263,199...37,263,282
JBrowse link
G Mir34a microRNA 34a decreases expression ISO Rifampin results in decreased expression of MIR34A mRNA CTD PMID:24552687 NCBI chr 5:167,092,491...167,092,592
Ensembl chr 5:167,092,491...167,092,592
JBrowse link
G Mir374b microRNA 374b increases expression ISO Rifampin results in increased expression of MIR374B mRNA CTD PMID:24552687 NCBI chr  X:74,443,648...74,443,715
Ensembl chr  X:74,443,648...74,443,715
JBrowse link
G Mir532 microRNA 532 decreases expression ISO Rifampin results in decreased expression of MIR532 mRNA CTD PMID:24552687 NCBI chr  X:16,109,870...16,109,948
Ensembl chr  X:16,109,870...16,109,948
JBrowse link
G Mir628 microRNA 628 decreases expression ISO Rifampin results in decreased expression of MIR628 mRNA CTD PMID:24552687 NCBI chr 8:79,679,458...79,679,541
Ensembl chr 8:79,679,458...79,679,541
JBrowse link
G Mir652 microRNA 652 decreases expression ISO Rifampin results in decreased expression of MIR652 mRNA CTD PMID:24552687 NCBI chr  X:114,002,534...114,002,614
Ensembl chr  X:114,002,534...114,002,614
JBrowse link
G Mir874 microRNA 874 decreases expression ISO Rifampin results in decreased expression of MIR874 mRNA CTD PMID:24552687 NCBI chr17:7,025,014...7,025,089
Ensembl chr17:7,025,014...7,025,089
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC gene mutant form] results in increased expression of MKI67 protein CTD PMID:21224054 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mmp3 matrix metallopeptidase 3 decreases secretion ISO Rifampin results in decreased secretion of MMP3 protein CTD PMID:24890593 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Rifampin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:24101390 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mr1 major histocompatibility complex, class I-related affects expression ISO Rifampin affects the expression of MR1 mRNA CTD PMID:25811541 NCBI chr13:72,771,992...72,789,861
Ensembl chr13:72,771,984...72,789,841
JBrowse link
G Myh6 myosin heavy chain 6 increases expression ISO Rifampin results in increased expression of MYH6 mRNA CTD PMID:24552687 NCBI chr15:33,605,653...33,629,730
Ensembl chr15:33,605,654...33,629,699
JBrowse link
G Naf1 nuclear assembly factor 1 ribonucleoprotein decreases expression ISO Rifampin results in decreased expression of NAF1 mRNA CTD PMID:24552687 NCBI chr16:24,582,000...24,612,773
Ensembl chr16:24,578,678...24,612,732
JBrowse link
G Nap1l5 nucleosome assembly protein 1-like 5 increases expression ISO Rifampin results in increased expression of NAP1L5 mRNA CTD PMID:24552687 NCBI chr 4:89,149,314...89,152,511
Ensembl chr 4:89,149,317...89,151,184
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO Camptothecin inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; Itraconazole promotes the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Ketoconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Miconazole promotes the reaction [Rifampin results in increased expression of NCOA1 mRNA]; NCOA1 protein inhibits the reaction [[NR1I2 protein co-treated with Rifampin] results in decreased expression of SLC22A1 mRNA]; NCOA1 protein inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in decreased expression of SLC22A1 mRNA]; oxiconazole promotes the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; pazopanib inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; pimecrolimus inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; Rifampin inhibits the reaction [NCOA1 protein binds to SLC22A1 promoter]; Rifampin inhibits the reaction [oxiconazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Rifampin promotes the reaction [[NCOA1 protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [[NR1I2 protein binds to NCOA1 protein] which binds to CYP27A1 gene]; Rifampin promotes the reaction [NCOA1 protein binds to and results in increased activity of NR1I2 protein]; Rifampin promotes the reaction [NCOA1 protein binds to HNF4A protein]; Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]; Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein] CTD PMID:11581012 PMID:12072427 PMID:16819505 PMID:17088262 PMID:17438109 PMID:17998298 PMID:21115105 PMID:21292004 PMID:22214767 PMID:23525103 PMID:25313206 PMID:26920453 PMID:27871908 PMID:28289823 PMID:29356861 NCBI chr 6:28,677,563...28,931,844
Ensembl chr 6:28,677,540...28,931,843
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO Rifampin promotes the reaction [NCOA2 protein binds to HNF4A protein] CTD PMID:21292004 NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598
JBrowse link
G Ncoa6 nuclear receptor coactivator 6 multiple interactions ISO NCOA6 promotes the reaction [Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]]; Rifampin promotes the reaction [[HNF4A co-treated with NCOA6] results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NCOA6] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [NCOA6 protein binds to HNF4A protein] CTD PMID:21292004 NCBI chr 3:150,919,317...150,990,391
Ensembl chr 3:150,919,317...150,960,030
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 multiple interactions ISO Rifampin inhibits the reaction [NCOR1 protein binds to and results in decreased activity of NR1I2 protein] CTD PMID:22214767 NCBI chr10:48,629,121...48,772,890
Ensembl chr10:48,629,121...48,772,890
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 multiple interactions ISO [NR1I2 protein binds to NCOR2 protein] inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Rifampin inhibits the reaction [NCOR2 protein binds to and results in decreased activity of NR1I2 protein]; Rifampin inhibits the reaction [NCOR2 protein binds to NR1I2 protein]; Rifampin inhibits the reaction [NR1I2 protein binds to NCOR2 protein]; Rifampin inhibits the reaction [trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]]; Rifampin promotes the reaction [NR1I2 protein binds to NCOR2 protein] CTD PMID:12072427 PMID:22214767 PMID:25313206 PMID:26883953 PMID:28289823 PMID:29356861 NCBI chr12:36,871,917...37,033,701
Ensembl chr12:36,871,999...37,033,701
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression ISO Rifampin results in increased expression of NFE2L2 protein CTD PMID:31678598 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfya nuclear transcription factor Y subunit alpha decreases expression ISO Rifampin results in decreased expression of NFYA mRNA CTD PMID:24552687 NCBI chr 9:14,551,752...14,577,002
Ensembl chr 9:14,551,758...14,576,967
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO Rifampin inhibits the reaction [Rotenone results in increased expression of NLRP3 protein] CTD PMID:26086368 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of NOS2 mRNA
Rifampin results in increased expression of NOS2 mRNA
CTD PMID:21224054 PMID:24552687 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Npas1 neuronal PAS domain protein 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of NPAS1 mRNA CTD PMID:21127053 NCBI chr 1:78,420,646...78,441,841
Ensembl chr 1:78,420,652...78,440,738
JBrowse link
G Nppb natriuretic peptide B multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of NPPB mRNA CTD PMID:21127053 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression ISO Rifampin results in increased expression of NR0B2 mRNA CTD PMID:15670600 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions ISO NR1H3 mutant form inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA] CTD PMID:23732298 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 affects response to substance
affects localization
decreases acetylation
increases response to substance
increases activity
decreases response to substance
multiple interactions
increases expression
increases localization
affects binding
ISO
EXP
NR1I2 protein affects the susceptibility to Rifampin
Rifampin affects the localization of NR1I2 protein
Rifampin results in decreased acetylation of NR1I2 protein
NR1I2 protein results in increased susceptibility to Rifampin
Rifampin results in increased activity of NR1I2 protein
NR1I2 protein mutant form results in decreased susceptibility to Rifampin
1,5-benzothiazepine analog promotes the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]; 7-acetoxy-6,7-dihydro-6-(4-methoxyphenyl)pyrrolo(2,1-d)(1,5)benzothiazepine inhibits the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]; [fexofenadine co-treated with Rifampin] results in increased activity of NR1I2 protein; [Ketoconazole co-treated with Rifampin] results in increased activity of NR1I2 protein; [Loperamide co-treated with Rifampin] results in increased activity of NR1I2 protein; [NR1I2 protein binds to NCOR2 protein] inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; [NR1I2 protein co-treated with Rifampin] results in decreased expression of CYP3A4 mRNA; [NR1I2 protein co-treated with Rifampin] results in decreased expression of SLC22A1 mRNA; [NR1I2 protein co-treated with Rifampin] results in decreased expression of SULT1E1 mRNA; [NR1I2 protein results in increased susceptibility to Rifampin] which results in decreased expression of SLC22A1 mRNA; [NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA; [NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein; [NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin; [Rifampin binds to and results in increased activity of NR1I2 protein] promotes the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]; [Rifampin binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; [Rifampin binds to and results in increased activity of NR1I2 protein] which results in increased expression of FGF19 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of NR1I2 protein; [Rifampin co-treated with NR1I2 protein] results in decreased expression of CYP8B1 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of FOXA1 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of GATA5 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of HDAC5 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of HNF4A mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of SERPINA4 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of STAT5A mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of ANGPTL4 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of AQP3 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of BHLHE40 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of BMP4 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CCN1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CCR6 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CCR7 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CDKN2B mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP26A1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP2B6 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP2S1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of EDN1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of EGR1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of EGR2 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of EGR4 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of EPAS1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of HBEGF mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of HEY1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of HIF1A mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP3 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP4 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of JUN mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF2 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF5 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF6 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of LEFTY1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of MAFF mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of NPAS1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of NPPB mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of PCK1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of PIP4K2A mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB8 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB9 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINE1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SGK2 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SGK2 protein; [Rifampin co-treated with NR1I2 protein] results in increased expression of SMAD9 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SOCS3 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of UGT1A1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of VEGFD mRNA; [Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein; [Rifampin results in increased activity of NR1I2 protein] inhibits the reaction [HNF4A protein binds to SULT1E1 enhancer]; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 protein; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of CYP2B6 mRNA; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of DHCR24 mRNA; [Rifampin results in increased expression of NR1I2 protein] which results in increased expression of and results in increased activity of CYP3A4 protein; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; Camptothecin inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; Camptothecin inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; caraway oil inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; Clove Oil inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; coriander oil inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]]]; Doxorubicin inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; enilconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; Epirubicin inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; Fluconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; hydroxyitraconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; INS protein inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA]; Itraconazole promotes the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Itraconazole promotes the reaction [Rifampin results in increased expression of NR1I2 mRNA]; jasmine oil inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]]; Ketoconazole inhibits the reaction [Rifampin binds to and results in increased activity of NR1I2 protein]; Ketoconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Ketoconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; lemongrass oil inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; Miconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA]; mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein]; N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]; NCOA1 protein inhibits the reaction [[NR1I2 protein co-treated with Rifampin] results in decreased expression of SLC22A1 mRNA]; NCOA1 protein inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in decreased expression of SLC22A1 mRNA]; NCOA6 promotes the reaction [Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]]; NR1I2 gene promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]; NR1I2 gene promotes the reaction [Rifampin results in increased metabolism of amprenavir]; NR1I2 gene promotes the reaction [Rifampin results in increased metabolism of Midazolam]; NR1I2 gene promotes the reaction [Rifampin results in increased metabolism of Nelfinavir]; NR1I2 gene promotes the reaction [Rifampin results in increased metabolism of Saquinavir]; NR1I2 mRNA promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; NR1I2 mRNA promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; NR1I2 protein affects the reaction [Rifampin results in increased expression of and results in increased activity of CYP2B6 protein]; NR1I2 protein affects the reaction [Rifampin results in increased expression of CYP2C9 mRNA]; NR1I2 protein affects the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; NR1I2 protein affects the reaction [Rifampin results in increased expression of CYP3A4 protein]; NR1I2 protein inhibits the reaction [[Rifampin co-treated with Benzo(a)pyrene] results in increased expression of AHR mRNA]; NR1I2 protein inhibits the reaction [Thapsigargin inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in decreased expression of CYP7A1 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in decreased expression of GCK protein]; NR1I2 protein promotes the reaction [Rifampin results in decreased expression of SLC2A2 protein]; NR1I2 protein promotes the reaction [Rifampin results in increased abundance of Lipids]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CES2 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP24A1 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of GADD45B mRNA]; ochratoxin A inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; Oils, Volatile inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; Oils, Volatile promotes the reaction [Rifampin results in increased expression of NR1I2 mRNA]; oxiconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]]; oxiconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; oxiconazole promotes the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; pazopanib inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; pazopanib inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; pimecrolimus inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; pimecrolimus inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; PK 11195 inhibits the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]; Rifampin binds to and results in increased activity of NR1I2 protein; Rifampin inhibits the reaction [NCOR1 protein binds to and results in decreased activity of NR1I2 protein]; Rifampin inhibits the reaction [NCOR2 protein binds to and results in decreased activity of NR1I2 protein]; Rifampin inhibits the reaction [NCOR2 protein binds to NR1I2 protein]; Rifampin inhibits the reaction [NR1I2 protein binds to NCOR2 protein]; Rifampin inhibits the reaction [oxiconazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Rifampin inhibits the reaction [oxiconazole results in increased expression of NR1I2 mRNA]; Rifampin inhibits the reaction [trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]]; Rifampin inhibits the reaction [trichostatin A results in increased acetylation of NR1I2 protein]; Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [[NCOA1 protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [[NR1I2 protein binds to NCOA1 protein] which binds to CYP27A1 gene]; Rifampin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [MED1 protein binds to and results in increased activity of NR1I2 protein]; Rifampin promotes the reaction [NCOA1 protein binds to and results in increased activity of NR1I2 protein]; Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]; Rifampin promotes the reaction [NR1I2 protein binds to CYP24A1 promoter]; Rifampin promotes the reaction [NR1I2 protein binds to CYP2A6 promoter]; Rifampin promotes the reaction [NR1I2 protein binds to CYP3A4 promoter]; Rifampin promotes the reaction [NR1I2 protein binds to HNF4A protein]; Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]; Rifampin promotes the reaction [NR1I2 protein binds to NCOR2 protein]; Rifampin promotes the reaction [NR1I2 protein binds to SGK2 promoter]; Rifampin promotes the reaction [NR1I2 protein results in decreased expression of SLC22A1 mRNA]; Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]; SGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA]; SGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of PCK1 mRNA]; sodium arsenite inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; sulforafan inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; trichostatin A affects the reaction [Rifampin affects the localization of NR1I2 protein]
Rifampin results in increased expression of NR1I2 mRNA; Rifampin results in increased expression of NR1I2 protein
Rifampin results in increased localization of NR1I2 protein
[Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A23-3A1 mRNA; [Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]] which results in increased expression of SULT2A1 mRNA; arsenite inhibits the reaction [Rifampin results in increased localization of NR1I2 protein]; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to CYP3A23-3A1 promoter]; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]; sodium arsenite inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A23-3A1 mRNA]
Rifampin binds to NR1I2 gene mutant form
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP1A2 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP2E1 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2B10 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2C protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP3A11 protein; [Rifampin binds to NR1I2 gene mutant form] which results in increased expression of CES2A mRNA; [Rifampin binds to NR1I2 gene mutant form] which results in increased expression of CYP3A11 mRNA; [Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]] which results in increased expression of SULT2A1 mRNA; NR1I2 affects the reaction [Rifampin results in increased activity of CYP3A4 protein]; Rifampin affects the localization of and results in increased activity of NR1I2 protein; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]
[Rifampin binds to NR1I2 protein] which binds to CYP2C8 promoter; Rifampin binds to NR1I2 protein
CTD PMID:11581012 PMID:12065438 PMID:12072427 PMID:12370413 PMID:12417264 PMID:12695340 PMID:12695351 PMID:14570758 PMID:14600250 PMID:14636322 PMID:14977870 PMID:15489543 PMID:15548381 PMID:15630458 PMID:15670600 PMID:15705662 PMID:15802384 PMID:15833926 PMID:15849716 PMID:15864135 PMID:15883047 PMID:15885729 PMID:15933212 PMID:16267138 PMID:16565514 PMID:16608920 PMID:16632523 PMID:16819505 PMID:16857725 PMID:17003103 PMID:17041008 PMID:17088262 PMID:17438109 PMID:17696253 PMID:17936928 PMID:17998298 PMID:18098064 PMID:18180267 PMID:18692084 PMID:18799805 PMID:19249324 PMID:19647009 PMID:19889628 PMID:20041327 PMID:20079722 PMID:20143881 PMID:20361990 PMID:20624464 PMID:20869355 PMID:21115097 PMID:21115105 PMID:21127053 PMID:21227907 PMID:21292004 PMID:21315811 PMID:21402137 PMID:21641981 PMID:21742782 PMID:21764778 PMID:21924250 PMID:22093699 PMID:22101211 PMID:22159698 PMID:22206814 PMID:22214767 PMID:22310298 PMID:22310326 PMID:22314385 PMID:22467028 PMID:22664347 PMID:22687401 PMID:22733800 PMID:22982774 PMID:23439660 PMID:23525103 PMID:23707768 PMID:23732298 PMID:23845848 PMID:23850985 PMID:23899473 PMID:24204015 PMID:25069801 PMID:25313206 PMID:25455453 PMID:25472953 PMID:25542144 PMID:25616597 PMID:25680588 PMID:25835148 PMID:26187274 PMID:26196221 PMID:26238175 PMID:26341324 PMID:26616219 PMID:26778350 PMID:26883953 PMID:26920453 PMID:27177772 PMID:27180241 PMID:27806127 PMID:27871908 PMID:27918128 PMID:28115241 PMID:28259787 PMID:28289823 PMID:28428138 PMID:28496040 PMID:28887089 PMID:29356861 PMID:29933105 PMID:30071242 PMID:30394306 PMID:30582956 PMID:31233785 PMID:31472229 PMID:32092453 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression
multiple interactions
EXP
ISO
Rifampin results in increased expression of NR1I3 mRNA
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP1A2 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP2E1 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2B10 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2C protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP3A11 protein
Rifampin results in increased expression of NR1I3 mRNA; Rifampin results in increased expression of NR1I3 protein
[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin; [Rifampin co-treated with Monocrotophos] results in increased expression of NR1I3 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of NR1I3 protein
CTD PMID:19118567 PMID:22733800 PMID:25835148 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions
increases expression
ISO Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]]]; NR3C1 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]
Rifampin results in increased expression of NR3C1 mRNA
CTD PMID:10219967 PMID:12673034 PMID:12695351 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nrl neural retina leucine zipper increases expression ISO Rifampin results in increased expression of NRL mRNA CTD PMID:24552687 NCBI chr15:34,197,115...34,201,408
Ensembl chr15:34,197,193...34,198,921
JBrowse link
G Obsl1 obscurin like cytoskeletal adaptor 1 decreases expression ISO Rifampin results in decreased expression of OBSL1 mRNA CTD PMID:24552687 NCBI chr 9:82,673,871...82,699,577
Ensembl chr 9:82,680,384...82,699,551
JBrowse link
G Ocln occludin affects localization ISO Rifampin affects the localization of OCLN protein CTD PMID:19577586 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Olr720 olfactory receptor 720 decreases expression ISO Rifampin results in decreased expression of OR4A47 mRNA CTD PMID:24552687 NCBI chr 3:78,716,472...78,717,401
Ensembl chr 3:78,716,472...78,717,401
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO Rifampin inhibits the reaction [[Acetaminophen co-treated with [ferric nitrate results in increased abundance of Iron]] results in increased cleavage of PARP1 protein] CTD PMID:31678598 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pax7 paired box 7 decreases expression ISO Rifampin results in decreased expression of PAX7 mRNA CTD PMID:24552687 NCBI chr 5:158,211,001...158,313,510
Ensembl chr 5:158,214,616...158,313,426
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of PCK1 mRNA; SGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of PCK1 mRNA] CTD PMID:24204015 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G Pclaf PCNA clamp associated factor increases expression ISO Rifampin results in increased expression of PCLAF mRNA CTD PMID:24552687 NCBI chr 8:71,514,281...71,526,182
Ensembl chr 8:71,514,281...71,526,182
JBrowse link
G Pdap1 PDGFA associated protein 1 decreases expression ISO Rifampin results in decreased expression of PDAP1 mRNA CTD PMID:24552687 NCBI chr12:11,240,775...11,251,002
Ensembl chr12:11,240,761...11,251,004
JBrowse link
G Pde4d phosphodiesterase 4D decreases expression ISO Rifampin results in decreased expression of PDE4D mRNA CTD PMID:24552687 NCBI chr 2:40,219,999...41,468,551
Ensembl chr 2:40,554,146...41,464,264
JBrowse link
G Peg3 paternally expressed 3 increases expression ISO Rifampin results in increased expression of PEG3 mRNA CTD PMID:24552687 NCBI chr 1:70,210,810...70,237,450
Ensembl chr 1:70,222,964...70,237,443
JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 multiple interactions ISO Rifampin inhibits the reaction [trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]] CTD PMID:26883953 NCBI chr 8:67,771,720...67,869,015
Ensembl chr 8:67,771,720...67,869,019
JBrowse link
G Pilra paired immunoglobin-like type 2 receptor alpha decreases expression ISO Rifampin results in decreased expression of PILRA mRNA CTD PMID:24552687 NCBI chr12:21,412,598...21,418,621
Ensembl chr12:21,412,538...21,420,169
JBrowse link
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of PIP4K2A mRNA CTD PMID:21127053 NCBI chr17:85,533,056...85,748,843 JBrowse link
G Pkd2l1 polycystin 2 like 1, transient receptor potential cation channel decreases expression ISO Rifampin results in decreased expression of PKD2L1 mRNA CTD PMID:24552687 NCBI chr 1:263,922,201...263,959,318
Ensembl chr 1:263,922,201...263,959,318
JBrowse link
G Pklr pyruvate kinase L/R increases expression ISO Rifampin results in increased expression of PKLR mRNA CTD PMID:24552687 NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592
JBrowse link
G Plat plasminogen activator, tissue type decreases expression ISO Rifampin results in decreased expression of PLAT mRNA CTD PMID:24552687 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Pon1 paraoxonase 1 increases expression ISO Rifampin results in increased expression of PON1 mRNA CTD PMID:26434531 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Por cytochrome p450 oxidoreductase increases activity ISO Rifampin results in increased activity of POR protein CTD PMID:12051692 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Pou2f1 POU class 2 homeobox 1 decreases expression ISO Rifampin results in decreased expression of POU2F1 mRNA CTD PMID:16837569 NCBI chr13:84,075,316...84,217,368
Ensembl chr13:84,083,632...84,217,366
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [Rifampin co-treated with PPARA protein co-treated with RXRA protein] results in decreased expression of UGDH mRNA CTD PMID:16292757 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg