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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:7beta-aminocephalosporanic acid
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Accession:CHEBI:2255 term browser browse the term
Definition:The alpha,beta-unsaturated monocarboxylic acid that is the active nucleus for the synthesis of cephalosporins and intermediates.
Synonyms:exact_synonym: (6R,7R)-3-(acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;   3-acetoxymethyl-7beta-amino-3,4-didehydrocepham-4-carboxylic acid
 related_synonym: (7R)-7-Aminocephalosporanate;   7-ACA;   7-Aminocephalosporanic acid;   7-Aminocephalosporinic acid;   Formula=C10H12N2O5S;   InChI=1S/C10H12N2O5S/c1-4(13)17-2-5-3-18-9-6(11)8(14)12(9)7(5)10(15)16/h6,9H,2-3,11H2,1H3,(H,15,16)/t6-,9-/m1/s1;   InChIKey=HSHGZXNAXBPPDL-HZGVNTEJSA-N;   SMILES=N12[C@@]([C@@H](C1=O)N)(SCC(=C2C(O)=O)COC(C)=O)[H]
 xref: Beilstein:8919572;   CAS:957-68-6;   KEGG:C07756;   LINCS:LSM-5737
 xref_mesh: MESH:C030735
 xref: PDBeChem:4KR;   PMID:1384868;   PMID:24003232;   Reaxys:622638
 cyclic_relationship: is_tautomer_of CHEBI:58501



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7beta-aminocephalosporanic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ampd3 adenosine monophosphate deaminase 3 increases expression ISO 7-aminocephalosporanic acid results in increased expression of AMPD3 mRNA CTD PMID:24211530 NCBI chr 1:164,884,823...164,929,899
Ensembl chr 1:164,885,320...164,929,887
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO 7-aminocephalosporanic acid results in increased expression of FTH1 mRNA CTD PMID:24211530 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO 7-aminocephalosporanic acid results in increased expression of FTL mRNA CTD PMID:24211530 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO 7-aminocephalosporanic acid results in increased expression of GCLM mRNA CTD PMID:24211530 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO 7-aminocephalosporanic acid results in increased expression of HMOX1 mRNA CTD PMID:24211530 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO 7-aminocephalosporanic acid results in increased expression of MYC mRNA CTD PMID:24211530 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO 7-aminocephalosporanic acid results in increased expression of NQO1 mRNA CTD PMID:24211530 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Sel1l3 SEL1L family member 3 increases expression ISO 7-aminocephalosporanic acid results in increased expression of SEL1L3 mRNA CTD PMID:24211530 NCBI chr14:57,775,515...57,882,076
Ensembl chr14:57,775,501...57,882,644
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO 7-aminocephalosporanic acid results in increased expression of SLC7A11 mRNA CTD PMID:24211530 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO 7-aminocephalosporanic acid results in increased expression of SQSTM1 mRNA CTD PMID:24211530 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Syne2 spectrin repeat containing nuclear envelope protein 2 decreases expression ISO 7-aminocephalosporanic acid results in decreased expression of SYNE2 mRNA CTD PMID:24211530 NCBI chr 6:94,537,088...94,848,085 JBrowse link
G Tnnt2 troponin T2, cardiac type decreases expression ISO 7-aminocephalosporanic acid results in decreased expression of TNNT2 mRNA CTD PMID:24211530 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO 7-aminocephalosporanic acid results in increased expression of TXNRD1 mRNA CTD PMID:24211530 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      application 19498
        pharmaceutical 19356
          drug 19356
            drug allergen 10101
              cephalosporin 546
                cephalosporanic acid 14
                  7beta-aminocephalosporanic acid 13
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic group 18718
                              organic divalent group 18702
                                organodiyl group 18702
                                  carbonyl group 18651
                                    carbonyl compound 18651
                                      carboxylic acid 18346
                                        carboacyl group 17469
                                          univalent carboacyl group 17469
                                            carbamoyl group 17285
                                              carboxamide 17285
                                                lactam 8308
                                                  beta-lactam 796
                                                    beta-lactam antibiotic 781
                                                      cephem 547
                                                        cephalosporin 546
                                                          cephalosporanic acid 14
                                                            7beta-aminocephalosporanic acid 13
paths to the root