CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 7beta-aminocephalosporanic acid
Accession: CHEBI:2255
browse the term
Definition: The alpha,beta-unsaturated monocarboxylic acid that is the active nucleus for the synthesis of cephalosporins and intermediates.
Synonyms: exact_synonym: (6R,7R)-3-(acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; 3-acetoxymethyl-7beta-amino-3,4-didehydrocepham-4-carboxylic acid
related_synonym: (7R)-7-Aminocephalosporanate; 7-ACA; 7-Aminocephalosporanic acid; 7-Aminocephalosporinic acid; Formula=C10H12N2O5S; InChI=1S/C10H12N2O5S/c1-4(13)17-2-5-3-18-9-6(11)8(14)12(9)7(5)10(15)16/h6,9H,2-3,11H2,1H3,(H,15,16)/t6-,9-/m1/s1; InChIKey=HSHGZXNAXBPPDL-HZGVNTEJSA-N; SMILES=N12[C@@]([C@@H](C1=O)N)(SCC(=C2C(O)=O)COC(C)=O)[H]
xref: Beilstein:8919572; CAS:957-68-6; KEGG:C07756; LINCS:LSM-5737
xref_mesh: MESH:C030735
xref: PDBeChem:4KR; PMID:1384868; PMID:24003232; Reaxys:622638
cyclic_relationship: is_tautomer_of CHEBI:58501
G
Ampd3
adenosine monophosphate deaminase 3
increases expression
ISO
7-aminocephalosporanic acid results in increased expression of AMPD3 mRNA
CTD
PMID:24211530
NCBI chr 1:164,884,823...164,929,899
Ensembl chr 1:164,885,320...164,929,887
G
Fth1
ferritin heavy chain 1
increases expression
ISO
7-aminocephalosporanic acid results in increased expression of FTH1 mRNA
CTD
PMID:24211530
NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
G
Ftl1
ferritin light chain 1
increases expression
ISO
7-aminocephalosporanic acid results in increased expression of FTL mRNA
CTD
PMID:24211530
NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725
G
Gclm
glutamate cysteine ligase, modifier subunit
increases expression
ISO
7-aminocephalosporanic acid results in increased expression of GCLM mRNA
CTD
PMID:24211530
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
G
Hmox1
heme oxygenase 1
increases expression
ISO
7-aminocephalosporanic acid results in increased expression of HMOX1 mRNA
CTD
PMID:24211530
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Myc
MYC proto-oncogene, bHLH transcription factor
increases expression
ISO
7-aminocephalosporanic acid results in increased expression of MYC mRNA
CTD
PMID:24211530
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
G
Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
ISO
7-aminocephalosporanic acid results in increased expression of NQO1 mRNA
CTD
PMID:24211530
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
G
Sel1l3
SEL1L family member 3
increases expression
ISO
7-aminocephalosporanic acid results in increased expression of SEL1L3 mRNA
CTD
PMID:24211530
NCBI chr14:57,775,515...57,882,076
Ensembl chr14:57,775,501...57,882,644
G
Slc7a11
solute carrier family 7 member 11
increases expression
ISO
7-aminocephalosporanic acid results in increased expression of SLC7A11 mRNA
CTD
PMID:24211530
NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
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Sqstm1
sequestosome 1
increases expression
ISO
7-aminocephalosporanic acid results in increased expression of SQSTM1 mRNA
CTD
PMID:24211530
NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
G
Syne2
spectrin repeat containing nuclear envelope protein 2
decreases expression
ISO
7-aminocephalosporanic acid results in decreased expression of SYNE2 mRNA
CTD
PMID:24211530
NCBI chr 6:94,537,088...94,848,085
Ensembl chr 6:94,537,088...94,848,064
G
Tnnt2
troponin T2, cardiac type
decreases expression
ISO
7-aminocephalosporanic acid results in decreased expression of TNNT2 mRNA
CTD
PMID:24211530
NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388
G
Txnrd1
thioredoxin reductase 1
increases expression
ISO
7-aminocephalosporanic acid results in increased expression of TXNRD1 mRNA
CTD
PMID:24211530
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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