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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:7beta-aminocephalosporanic acid
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Accession:CHEBI:2255 term browser browse the term
Definition:The alpha,beta-unsaturated monocarboxylic acid that is the active nucleus for the synthesis of cephalosporins and intermediates.
Synonyms:exact_synonym: (6R,7R)-3-(acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;   3-acetoxymethyl-7beta-amino-3,4-didehydrocepham-4-carboxylic acid
 related_synonym: (7R)-7-Aminocephalosporanate;   7-ACA;   7-Aminocephalosporanic acid;   7-Aminocephalosporinic acid;   Formula=C10H12N2O5S;   InChI=1S/C10H12N2O5S/c1-4(13)17-2-5-3-18-9-6(11)8(14)12(9)7(5)10(15)16/h6,9H,2-3,11H2,1H3,(H,15,16)/t6-,9-/m1/s1;   InChIKey=HSHGZXNAXBPPDL-HZGVNTEJSA-N;   SMILES=N12[C@@]([C@@H](C1=O)N)(SCC(=C2C(O)=O)COC(C)=O)[H]
 xref: Beilstein:8919572;   CAS:957-68-6;   KEGG:C07756;   LINCS:LSM-5737
 xref_mesh: MESH:C030735
 xref: PDBeChem:4KR;   PMID:1384868;   PMID:24003232;   Reaxys:622638
 cyclic_relationship: is_tautomer_of CHEBI:58501


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7beta-aminocephalosporanic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ampd3 adenosine monophosphate deaminase 3 increases expression ISO 7-aminocephalosporanic acid results in increased expression of AMPD3 mRNA CTD PMID:24211530 NCBI chr 1:175,585,301...175,630,479
Ensembl chr 1:175,586,097...175,630,467
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO 7-aminocephalosporanic acid results in increased expression of FTH1 mRNA CTD PMID:24211530 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO 7-aminocephalosporanic acid results in increased expression of FTL mRNA CTD PMID:24211530 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO 7-aminocephalosporanic acid results in increased expression of GCLM mRNA CTD PMID:24211530 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO 7-aminocephalosporanic acid results in increased expression of HMOX1 mRNA CTD PMID:24211530 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO 7-aminocephalosporanic acid results in increased expression of MYC mRNA CTD PMID:24211530 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO 7-aminocephalosporanic acid results in increased expression of NQO1 mRNA CTD PMID:24211530 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Sel1l3 SEL1L family member 3 increases expression ISO 7-aminocephalosporanic acid results in increased expression of SEL1L3 mRNA CTD PMID:24211530 NCBI chr14:60,122,968...60,229,565
Ensembl chr14:60,123,169...60,229,734
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO 7-aminocephalosporanic acid results in increased expression of SLC7A11 mRNA CTD PMID:24211530 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO 7-aminocephalosporanic acid results in increased expression of SQSTM1 mRNA CTD PMID:24211530 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Syne2 spectrin repeat containing nuclear envelope protein 2 decreases expression ISO 7-aminocephalosporanic acid results in decreased expression of SYNE2 mRNA CTD PMID:24211530 NCBI chr 6:98,884,269...99,153,551 JBrowse link
G Tnnt2 troponin T2, cardiac type decreases expression ISO 7-aminocephalosporanic acid results in decreased expression of TNNT2 mRNA CTD PMID:24211530 NCBI chr13:52,662,974...52,680,992
Ensembl chr13:52,662,996...52,680,990
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO 7-aminocephalosporanic acid results in increased expression of TXNRD1 mRNA CTD PMID:24211530 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19761
    role 19711
      application 19401
        pharmaceutical 19289
          drug 19289
            drug allergen 9926
              cephalosporin 543
                cephalosporanic acid 14
                  7beta-aminocephalosporanic acid 13
Path 2
Term Annotations click to browse term
  CHEBI ontology 19761
    subatomic particle 19759
      composite particle 19759
        hadron 19759
          baryon 19759
            nucleon 19759
              atomic nucleus 19759
                atom 19759
                  main group element atom 19653
                    p-block element atom 19653
                      carbon group element atom 19569
                        carbon atom 19559
                          organic molecular entity 19559
                            organic group 18593
                              organic divalent group 18584
                                organodiyl group 18584
                                  carbonyl group 18499
                                    carbonyl compound 18499
                                      carboxylic acid 18151
                                        carboacyl group 17410
                                          univalent carboacyl group 17410
                                            carbamoyl group 17208
                                              carboxamide 17208
                                                lactam 8046
                                                  beta-lactam 794
                                                    beta-lactam antibiotic 779
                                                      cephem 544
                                                        cephalosporin 543
                                                          cephalosporanic acid 14
                                                            7beta-aminocephalosporanic acid 13
paths to the root