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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:aminopropionitrile
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Accession:CHEBI:22525 term browser browse the term
Synonyms:exact_synonym: aminopropanenitrile
 related_synonym: Formula=C3H6N2



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beta-aminopropionitrile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 B cell leukemia/lymphoma 2 decreases expression ISO Aminopropionitrile results in decreased expression of BCL2 protein CTD PMID:24614111 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Eln elastin multiple interactions
decreases expression
ISO Aminopropionitrile results in increased expression of and results in increased degradation of ELN protein modified form
Aminopropionitrile results in decreased expression of ELN mRNA
CTD PMID:1680324 NCBI chr 5:134,731,449...134,776,300
Ensembl chr 5:134,731,447...134,776,177
JBrowse link
G Lox lysyl oxidase decreases activity
multiple interactions
ISO
EXP
Aminopropionitrile results in decreased activity of LOX protein
Aminopropionitrile inhibits the reaction [cupric chloride results in increased activity of LOX protein]
CTD PMID:16023247 PMID:19524603 PMID:22367676 PMID:25044713 NCBI chr18:52,649,132...52,662,939
Ensembl chr18:52,649,139...52,662,939
JBrowse link
G Mmp14 matrix metallopeptidase 14 (membrane-inserted) decreases activity ISO Aminopropionitrile results in decreased activity of MMP14 protein CTD PMID:24014025 NCBI chr14:54,669,055...54,679,913
Ensembl chr14:54,669,069...54,682,821
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression
multiple interactions
ISO Aminopropionitrile results in increased expression of MMP2 protein
Propylthiouracil inhibits the reaction [Aminopropionitrile results in increased expression of MMP2 protein]
CTD PMID:33462684 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
ISO Propylthiouracil inhibits the reaction [Aminopropionitrile results in increased expression of MMP9 protein] CTD PMID:33462684 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO Aminopropionitrile results in decreased expression of PCNA protein CTD PMID:24614111 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
JBrowse link
G Smad2 SMAD family member 2 increases phosphorylation
multiple interactions
ISO Aminopropionitrile results in increased phosphorylation of SMAD2 protein
Propylthiouracil inhibits the reaction [Aminopropionitrile results in increased phosphorylation of SMAD2 protein]
CTD PMID:33462684 NCBI chr18:76,369,898...76,444,819
Ensembl chr18:76,374,651...76,444,034
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22188
    chemical entity 22187
      group 22082
        pseudohalo group 4677
          cyano group 4677
            nitrile 4677
              aliphatic nitrile 2286
                aminopropionitrile 8
                  alpha-aminopropionitrile + 0
                  beta-aminopropionitrile + 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 22188
    subatomic particle 22180
      composite particle 22180
        hadron 22180
          baryon 22180
            nucleon 22180
              atomic nucleus 22180
                atom 22180
                  main group element atom 22114
                    p-block element atom 22114
                      carbon group element atom 21915
                        carbon atom 21840
                          organic molecular entity 21840
                            one-carbon compound 18585
                              hydrogen cyanide 4894
                                cyanides 4877
                                  nitrile 4677
                                    aliphatic nitrile 2286
                                      aminopropionitrile 8
                                        alpha-aminopropionitrile + 0
                                        beta-aminopropionitrile + 8
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