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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:amino aldehyde
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Accession:CHEBI:22492 term browser browse the term
Definition:Any aldehyde which contains an amino group.
Synonyms:xref: PMID:17105264


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alpha-methyl-L-dopa term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase increases methylation
decreases activity
ISO COMT protein results in increased methylation of Methyldopa
Methyldopa results in decreased activity of COMT protein
CTD PMID:7053299, PMID:11160877 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases activity ISO Methyldopa analog results in decreased activity of GSTA1 protein CTD PMID:8131222 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases activity ISO Methyldopa analog results in decreased activity of GSTM1 protein CTD PMID:8131222 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases activity ISO Methyldopa analog results in decreased activity of GSTP1 protein CTD PMID:8131222 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Prl prolactin increases expression
increases secretion
ISO Methyldopa results in increased expression of PRL protein
Methyldopa results in increased secretion of PRL protein
CTD PMID:1867878, PMID:7265421 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Ren renin decreases activity EXP Methyldopa results in decreased activity of REN protein CTD PMID:145319 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [isoborneol results in decreased expression of ABCB1A protein] CTD PMID:26593909 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [indolo(3,2-b)carbazole results in increased expression of ABCG2 mRNA] CTD PMID:17077187 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACAA2 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACAA2 mRNA]
CTD PMID:25566086 NCBI chr18:70,733,872...70,762,395
Ensembl chr18:70,733,872...70,762,395
JBrowse link
G Ace angiotensin I converting enzyme multiple interactions ISO [Butyrates co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the localization of ACE protein mutant form; [Butyrates co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased activity of ACE protein mutant form CTD PMID:20454656 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ache acetylcholinesterase multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride results in decreased stability of ACHE protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride results in increased degradation of ACHE protein] CTD PMID:22944069 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acta2 actin alpha 2, smooth muscle decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACTA2 mRNA CTD PMID:25566086 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Actb actin, beta decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACTB mRNA CTD PMID:15857753 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACTC1 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACTC1 mRNA]
CTD PMID:25566086 NCBI chr 3:105,507,403...105,512,939
Ensembl chr 3:105,507,403...105,512,939
JBrowse link
G Adssl1 adenylosuccinate synthase like 1 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ADSSL1 mRNA] CTD PMID:25566086 NCBI chr 6:137,184,818...137,206,694
Ensembl chr 6:137,184,820...137,206,693
JBrowse link
G Agrp agouti related neuropeptide increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AGRP mRNA CTD PMID:20061341 NCBI chr19:37,525,941...37,584,875
Ensembl chr19:37,526,419...37,528,011
JBrowse link
G Agt angiotensinogen multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in decreased degradation of TP53 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [AGT protein results in increased degradation of SYP protein] CTD PMID:18487452, PMID:26612707 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases localization
affects localization
decreases expression
ISO
EXP
AHR protein affects the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [AHR protein results in decreased expression of VIM protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [geldanamycin results in decreased expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [herbimycin results in decreased expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [monorden results in decreased expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of and affects the localization of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of and results in decreased expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [AHR protein binds to VIM protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased localization of AHR protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the localization of AHR protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [geldanamycin results in increased degradation of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of and affects the localization of AHR protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of AHR protein
CTD PMID:10497241, PMID:10722677, PMID:10922479, PMID:12002481, PMID:12237327, PMID:12606767, PMID:15385644, PMID:15899923, PMID:16891617, PMID:17445780, PMID:20057149, PMID:27752740, PMID:31676321 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AKR1B1 mRNA CTD PMID:21215737 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AKR1B10 mRNA CTD PMID:21215737 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 multiple interactions
increases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [tolfenamic acid inhibits the reaction [AKR1C3 protein results in decreased susceptibility to Cisplatin]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AKR1C3 mRNA
CTD PMID:21215737, PMID:23165153 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation
increases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [cadmium acetate results in decreased expression of AKT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium results in increased phosphorylation of AKT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [triptolide results in decreased phosphorylation of AKT1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of AKT1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AKT1 protein
CTD PMID:24085292, PMID:24449419, PMID:24933620, PMID:32061799 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Anln anillin, actin binding protein decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ANLN mRNA CTD PMID:25566086 NCBI chr 8:23,336,455...23,397,122
Ensembl chr 8:23,337,621...23,390,773
JBrowse link
G Aoc3 amine oxidase, copper containing 3 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of AOC3 mRNA CTD PMID:25566086 NCBI chr10:89,251,370...89,259,313
Ensembl chr10:89,251,370...89,259,313
JBrowse link
G Aph1a aph-1 homolog A, gamma secretase subunit decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of APH1A mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of APH1A mRNA]
CTD PMID:25566086 NCBI chr 2:198,006,247...198,009,837
Ensembl chr 2:198,006,316...198,009,830
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [APP protein modified form results in decreased expression of and results in decreased activity of TERT protein] CTD PMID:21520056 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased degradation of APPL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Poly I-C results in increased degradation of APPL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [resiquimod results in increased degradation of APPL1 protein] CTD PMID:25780039 NCBI chr16:2,560,103...2,602,035
Ensembl chr16:2,563,520...2,602,103
JBrowse link
G Aqp2 aquaporin 2 decreases degradation ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of AQP2 protein CTD PMID:21734099 NCBI chr 7:141,237,802...141,242,837
Ensembl chr 7:141,237,768...141,245,165
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen inhibits the reaction [AQP3 protein results in increased stability of EPAS1 protein]] CTD PMID:23545307 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Aqp5 aquaporin 5 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen inhibits the reaction [AQP5 protein results in increased stability of EPAS1 protein]] CTD PMID:23545307 NCBI chr 7:141,249,044...141,252,576
Ensembl chr 7:141,249,044...141,252,578
JBrowse link
G Ar androgen receptor multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [decursin results in increased degradation of AR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Niclosamide results in decreased expression of and results in increased degradation of AR protein alternative form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulforafan results in decreased expression of AR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Testosterone results in increased expression of AR mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [trichostatin A results in decreased expression of AR protein] CTD PMID:12376534, PMID:17723170, PMID:19805354, PMID:24740322 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arg1 arginase 1 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ARG1 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ARG1 mRNA]
CTD PMID:25566086 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ARIH1 protein
2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ARIH1 protein]
CTD PMID:25624349 NCBI chr 8:64,166,359...64,268,555
Ensembl chr 8:64,166,360...64,268,555
JBrowse link
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ARL6IP5 mutant form inhibits the reaction [Morphine results in increased expression of OPRD1 protein]] CTD PMID:21600884 NCBI chr 4:129,574,363...129,598,240
Ensembl chr 4:129,574,264...129,598,915
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases expression
multiple interactions
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ARNT mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in increased degradation of ARNT protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ARNT protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [SP1 protein binds to ARNT promoter]; bisindolylmaleimide I inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ARNT mRNA]
CTD PMID:14529614, PMID:15899923, PMID:16880289 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Art3 ADP-ribosyltransferase 3 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ART3 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ART3 mRNA]
CTD PMID:25566086 NCBI chr14:17,143,037...17,225,389
Ensembl chr14:17,143,040...17,225,389
JBrowse link
G Asb2 ankyrin repeat and SOCS box-containing 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ASB2 mRNA CTD PMID:25566086 NCBI chr 6:127,212,325...127,248,451
Ensembl chr 6:127,212,273...127,248,372
JBrowse link
G Atf3 activating transcription factor 3 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF3 protein
Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF3 protein]
CTD PMID:23593480 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atf4 activating transcription factor 4 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF4 protein
Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF4 protein]
CTD PMID:14604972, PMID:17912641, PMID:23593480 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atg12 autophagy related 12 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of ATG12 mRNA CTD PMID:25566086 NCBI chr18:40,721,799...40,732,143
Ensembl chr18:40,721,800...40,732,126
JBrowse link
G Atg13 autophagy related 13 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [ATG13 protein results in decreased expression of SQSTM1 protein] CTD PMID:27629431 NCBI chr 3:80,580,549...80,614,554
Ensembl chr 3:80,581,247...80,601,410
JBrowse link
G Atg7 autophagy related 7 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [ATG7 protein results in decreased expression of SQSTM1 protein] CTD PMID:27629431 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
JBrowse link
G Atp13a2 ATPase cation transporting 13A2 decreases response to substance ISO ATP13A2 protein results in decreased susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde analog CTD PMID:22847264 NCBI chr 5:159,512,208...159,531,631
Ensembl chr 5:159,512,285...159,531,637
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium Chloride results in decreased expression of ATP1A1 protein] CTD PMID:10506578 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [troglitazone results in decreased expression of ATP5F1B mRNA] CTD PMID:20860658 NCBI chr 7:2,504,708...2,511,748
Ensembl chr 7:2,504,695...2,511,749
JBrowse link
G Atp7b ATPase copper transporting beta decreases degradation ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of ATP7B protein CTD PMID:21189263 NCBI chr16:74,865,516...74,944,935
Ensembl chr16:74,865,516...74,945,286
JBrowse link
G Aurka aurora kinase A multiple interactions ISO [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Nocodazole] results in increased expression of and results in increased phosphorylation of AURKA protein; MLN8054 inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Nocodazole] results in increased phosphorylation of AURKA protein] CTD PMID:24976383 NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
JBrowse link
G Aurkb aurora kinase B multiple interactions ISO 4-(4-(N-benzoylamino)anilino)-6-methoxy-7-(3-(1-morpholino)propoxy)quinazoline inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Nocodazole] results in increased phosphorylation of AURKB protein]; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Nocodazole] results in increased phosphorylation of AURKB protein CTD PMID:24976383 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Bach1 BTB domain and CNC homolog 1 multiple interactions
increases ubiquitination
ISO 2-tert-butylhydroquinone promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of BACH1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tetrachlorobenzoquinone results in increased degradation of BACH1 protein]; hydroquinone promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of BACH1 protein]; quinone promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of BACH1 protein] CTD PMID:27393035, PMID:28645578 NCBI chr11:27,364,913...27,398,713
Ensembl chr11:27,364,916...27,398,842
JBrowse link
G Bag3 BAG cochaperone 3 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Staurosporine results in increased degradation of BAG3 protein] CTD PMID:19352495 NCBI chr 1:199,941,258...199,965,191
Ensembl chr 1:199,941,161...199,965,191
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arachidonic Acid affects the localization of BAX protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of BAX protein CTD PMID:15782132, PMID:19540902 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein] CTD PMID:20530418 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [evodiamine results in increased cleavage of BCL2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [trimethyltin chloride results in decreased expression of BCL2 protein]
benzyloxycarbonyl-valyl-alanyl-aspartic acid promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of BCL2 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of BCL2; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of BCL2 protein
CTD PMID:19540902, PMID:20005289, PMID:20100472, PMID:20449726, PMID:23423712 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2L1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of BCL2L1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Topotecan results in increased degradation of BCL2L1 protein]
CTD PMID:16960866, PMID:19540902, PMID:19812371 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions
increases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BIRC3 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BIRC3 protein
CTD PMID:14527959, PMID:24085292 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression
multiple interactions
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BIRC5 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [(+)-JQ1 compound results in decreased expression of BIRC5 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[pifithrin co-treated with Topotecan] results in increased degradation of BIRC5 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Capsaicin results in decreased expression of BIRC5 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Quercetin results in decreased expression of BIRC5 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased susceptibility to [Oxaliplatin results in decreased expression of BIRC5 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of BIRC5 mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Topotecan results in increased degradation of BIRC5 protein]
CTD PMID:16328441, PMID:17510429, PMID:17548900, PMID:19812371, PMID:19939880, PMID:20708607, PMID:23872705, PMID:25566086 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Blvrb biliverdin reductase B increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BLVRB mRNA CTD PMID:25566086 NCBI chr 1:84,256,063...84,273,726
Ensembl chr 1:84,256,159...84,274,075
JBrowse link
G Bnip3 BCL2 interacting protein 3 multiple interactions
increases expression
ISO [arsenic trioxide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of BNIP3 mRNA; arsenic trioxide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BNIP3 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Valproic Acid results in increased expression of BNIP3 mRNA] CTD PMID:25446377 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Bok BCL2 family apoptosis regulator BOK multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of BOK mRNA CTD PMID:25566086 NCBI chr 9:100,829,593...100,840,498
Ensembl chr 9:100,829,552...100,840,504
JBrowse link
G Brd4 bromodomain containing 4 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ARV-825 results in increased degradation of BRD4 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [BRD4 mutant form affects the localization of RELA protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [STA 9090 inhibits the reaction [PKD1 gene mutant form results in increased expression of BRD4 protein]]
CTD PMID:23686307, PMID:25877301, PMID:26051217 NCBI chr 7:14,222,101...14,303,055
Ensembl chr 7:14,222,101...14,303,055
JBrowse link
G C1qb complement C1q B chain multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of C1QB mRNA] CTD PMID:25566086 NCBI chr 5:155,246,444...155,251,995
Ensembl chr 5:155,246,447...155,252,003
JBrowse link
G Ca14 carbonic anhydrase 14 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CAR14 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CAR14 mRNA]
CTD PMID:25566086 NCBI chr 2:198,010,142...198,017,635
Ensembl chr 2:198,010,349...198,016,898
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H decreases expression
decreases degradation
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CACNA1H mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of CACNA1H protein
CTD PMID:25566086, PMID:30552955 NCBI chr10:14,730,932...14,789,201
Ensembl chr10:14,730,941...14,788,617
JBrowse link
G Canx calnexin affects localization ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the localization of CANX protein CTD PMID:17912641 NCBI chr10:35,800,942...35,833,939
Ensembl chr10:35,800,942...35,833,861
JBrowse link
G Casp1 caspase 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP1 protein]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP1 protein]] CTD PMID:15914627 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases cleavage
increases activity
ISO
EXP
[arsenic trioxide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased cleavage of CASP3 protein; [XBP1 mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] promotes the reaction [Tobacco Smoke Pollution analog results in increased cleavage of CASP3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [evodiamine results in increased activity of and results in increased cleavage of CASP3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of and results in increased activity of CASP3 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CASP3 protein modified form
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of CASP3 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CASP3 protein
Acetylcysteine inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CASP3 protein]
CTD PMID:15498850, PMID:15725397, PMID:16880202, PMID:18463101, PMID:18790767, PMID:20005289, PMID:20100472, PMID:20449726, PMID:20649845, PMID:23684743, PMID:25449439, PMID:25568320, PMID:29944914 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 increases activity ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CASP7 protein CTD PMID:19139269 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 multiple interactions
increases activity
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of and results in increased activity of CASP8 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CASP8 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP8 protein]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP8 protein]]
CTD PMID:15498850, PMID:15914627, PMID:20100472, PMID:20449726, PMID:20671745 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of and results in increased activity of CASP9 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CASP9 protein
CTD PMID:15498850, PMID:16880202 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CAT mRNA
CAT protein inhibits the reaction [[SOD2 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of HDAC2 protein]
CTD PMID:20061341, PMID:24973648 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CAV1 protein
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CAV1 mRNA
CTD PMID:19706615, PMID:25566086 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cavin1 caveolae associated protein 1 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CAVIN1 mRNA] CTD PMID:25566086 NCBI chr10:88,862,513...88,874,495
Ensembl chr10:88,860,733...88,874,528
JBrowse link
G Cavin2 caveolae associated protein 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CAVIN2 mRNA CTD PMID:25566086 NCBI chr 9:55,244,136...55,256,153
Ensembl chr 9:55,243,255...55,256,340
JBrowse link
G Cbr3 carbonyl reductase 3 increases expression ISO [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L2 protein] which results in increased expression of CBR3 mRNA CTD PMID:20806931 NCBI chr11:33,909,417...33,917,674
Ensembl chr11:33,909,439...33,917,674
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Chloroquine results in increased expression of CCL2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased secretion of CCL2 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA]
CTD PMID:10541287, PMID:11230753, PMID:11698246, PMID:15139008, PMID:19945525 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CCNA2 mRNA CTD PMID:20061341 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 multiple interactions
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [arsenite results in increased ubiquitination of CCNB1 protein]
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CCNB1 mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CCNB1 mRNA
CTD PMID:17373649, PMID:20061341, PMID:25566086 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnb2 cyclin B2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CCNB2 mRNA CTD PMID:20061341 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression
increases phosphorylation
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [3,3'-diindolylmethane analog results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [alopestatin metabolite results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Carbamazepine results in decreased expression of CCND1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Carbamazepine results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Drugs, Chinese Herbal results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [kahweol results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [lysocellin results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [nickel chloride results in decreased expression of and results in increased degradation of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [nickel chloride results in decreased phosphorylation of CCND1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CCND1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of CCND1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dexamethasone results in increased degradation of CCND1 protein]; Tetrachlorodibenzodioxin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of CCND1 protein]
CTD PMID:15247282, PMID:16051428, PMID:16525630, PMID:16707792, PMID:16965676, PMID:18792914, PMID:20394812, PMID:21472727, PMID:24231000, PMID:27424123, PMID:28548306, PMID:30703377 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CCND3 mRNA CTD PMID:20061341 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccs copper chaperone for superoxide dismutase multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Copper Sulfate co-treated with 2,3,2-tetramine] results in increased degradation of CCS protein] CTD PMID:12832419 NCBI chr 1:220,075,251...220,096,319
Ensembl chr 1:220,075,247...220,096,404
JBrowse link
G Cd14 CD14 molecule increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CD14 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CD14 mRNA]
CTD PMID:25566086 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd1d1 CD1d1 molecule increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CD1D1 mRNA CTD PMID:25566086 NCBI chr 2:186,330,298...186,333,805
Ensembl chr 2:186,330,298...186,333,805
JBrowse link
G Cd248 CD248 molecule decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CD248 mRNA CTD PMID:25566086 NCBI chr 1:220,353,308...220,355,872
Ensembl chr 1:220,446,425...220,448,989
JBrowse link
G Cdc20 cell division cycle 20 multiple interactions
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium Chloride results in increased degradation of CDC20 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDC20 mRNA
CTD PMID:20054826, PMID:20061341, PMID:25566086 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdc25b cell division cycle 25B decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDC25B mRNA CTD PMID:20061341 NCBI chr 3:123,731,539...123,741,696
Ensembl chr 3:123,731,539...123,741,339
JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDC25C mRNA CTD PMID:20061341 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
JBrowse link
G Cdca3 cell division cycle associated 3 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDCA3 mRNA CTD PMID:20061341 NCBI chr 4:157,347,876...157,351,889
Ensembl chr 4:157,348,020...157,351,604
JBrowse link
G Cdh3 cadherin 3 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CDH3 mRNA CTD PMID:25566086 NCBI chr19:38,668,957...38,719,801
Ensembl chr19:38,669,230...38,719,677
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDK1 mRNA
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CDK1 mRNA
CTD PMID:20061341, PMID:25566086 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [troglitazone results in decreased expression of CDK2 protein] CTD PMID:15610522 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases degradation ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of CDKN1B protein CTD PMID:17283133 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDKN2A mRNA CTD PMID:20061341 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDKN2C mRNA CTD PMID:20061341 NCBI chr 5:129,347,731...129,352,886
Ensembl chr 5:129,347,732...129,352,886
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDKN3 mRNA CTD PMID:20061341 NCBI chr15:23,553,171...23,564,538
Ensembl chr15:23,553,128...23,564,535
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases ubiquitination
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of CEBPA protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NSC606985 results in decreased expression of CEBPA protein]
CTD PMID:19662097 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and results in increased localization of CEBPB protein; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and results in increased localization of CEBPB protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [N-acetylsphingosine results in decreased localization of CEBPB protein]
CTD PMID:11779194, PMID:15319326 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and results in increased localization of CEBPD protein; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and results in increased localization of CEBPD protein] CTD PMID:11779194 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Cebpe CCAAT/enhancer binding protein epsilon multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tretinoin results in increased expression of CEBPE protein] CTD PMID:20945414 NCBI chr15:33,356,119...33,357,517
Ensembl chr15:33,355,947...33,358,138
JBrowse link
G Cenpa centromere protein A decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CENPA mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CENPA mRNA]
CTD PMID:25566086 NCBI chr 6:27,072,259...27,080,863
Ensembl chr 6:27,072,166...27,080,856
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator affects expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the expression of CFLAR protein alternative form
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [(+)-JQ1 compound results in decreased expression of CFLAR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [alvocidib results in decreased expression of CFLAR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Quercetin results in decreased expression of CFLAR protein alternative form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [shogaol results in decreased expression of CFLAR protein modified form]
CTD PMID:16951203, PMID:17510429, PMID:18980244, PMID:25619640, PMID:26415225 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat results in increased activity of CFTR protein mutant form] CTD PMID:18230692 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Chek1 checkpoint kinase 1 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CHEK1 mRNA CTD PMID:20061341 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CHRM2 mRNA] CTD PMID:25566086 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex increases activity ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CHUK protein CTD PMID:24085292 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Cidea cell death-inducing DFFA-like effector a decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CIDEA mRNA CTD PMID:25566086 NCBI chr18:63,082,861...63,108,450
Ensembl chr18:63,098,144...63,108,051
JBrowse link
G Cited4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CITED4 mRNA CTD PMID:25566086 NCBI chr 5:139,597,731...139,598,622
Ensembl chr 5:139,597,731...139,598,622
JBrowse link
G Ckb creatine kinase B multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CKB mRNA CTD PMID:25566086 NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837
JBrowse link
G Ckmt2 creatine kinase, mitochondrial 2 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CKMT2 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CKMT2 mRNA]
CTD PMID:25566086 NCBI chr 2:21,422,680...21,452,797
Ensembl chr 2:21,422,818...21,437,193
JBrowse link
G Cldn4 claudin 4 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CLDN4 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CLDN4 mRNA]
CTD PMID:25566086 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005
JBrowse link
G Clip4 CAP-GLY domain containing linker protein family, member 4 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CLIP4 mRNA] CTD PMID:25566086 NCBI chr 6:23,222,020...23,316,962
Ensembl chr 6:23,222,021...23,316,962
JBrowse link
G Cmya5 cardiomyopathy associated 5 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CMYA5 mRNA] CTD PMID:25566086 NCBI chr 2:22,646,694...22,744,536
Ensembl chr 2:22,646,712...22,744,407
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [gemcitabine results in increased expression of CNR1 mRNA] CTD PMID:21525939 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [gemcitabine results in increased expression of CNR2 mRNA] CTD PMID:21525939 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Asbestos, Amosite results in increased expression of COL1A1 mRNA] CTD PMID:11306436 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Commd1 copper metabolism domain containing 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of COMMD1 protein CTD PMID:23401744 NCBI chr14:107,664,321...107,759,974
Ensembl chr14:107,664,255...107,760,191
JBrowse link
G Corin corin, serine peptidase decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CORIN mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CORIN mRNA]
CTD PMID:25566086 NCBI chr14:38,247,379...38,474,931
Ensembl chr14:38,247,791...38,473,648
JBrowse link
G Cox4i2 cytochrome c oxidase subunit 4i2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of COX4I2 mRNA CTD PMID:25566086 NCBI chr 3:148,234,546...148,245,424
Ensembl chr 3:148,234,193...148,245,416
JBrowse link
G Cpxm1 carboxypeptidase X (M14 family), member 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CPXM1 mRNA CTD PMID:20061341, PMID:25566086 NCBI chr 3:122,913,886...122,920,684
Ensembl chr 3:122,913,886...122,920,684
JBrowse link
G Crct1 cysteine-rich C-terminal 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CRCT1 mRNA CTD PMID:25566086 Ensembl chr 2:193,330,397...193,330,699 JBrowse link
G Crebbp CREB binding protein multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Valproic Acid results in decreased expression of CREBBP protein] CTD PMID:27381264 NCBI chr10:11,590,994...11,721,039
Ensembl chr10:11,595,044...11,721,039
JBrowse link
G Crip2 cysteine-rich protein 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CRIP2 mRNA CTD PMID:25566086 NCBI chr 6:137,953,545...137,958,491
Ensembl chr 6:137,953,545...137,958,490
JBrowse link
G Cryaa crystallin, alpha A decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CRYAA mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CRYAA protein CTD PMID:15914627 NCBI chr20:10,438,444...10,442,189
Ensembl chr20:10,438,444...10,442,187
JBrowse link
G Cryab crystallin, alpha B increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CRYAB mRNA CTD PMID:15914627 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
decreases degradation
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Aspirin results in increased ubiquitination of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in increased degradation of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Drugs, Chinese Herbal results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [quinocetone results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [RASSF5 protein results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfide results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfone results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Vitamin A results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Nitroglycerin results in increased degradation of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and affects the localization of CTNNB1 protein; thymoquinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of CTNNB1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the phosphorylation of and affects the localization of CTNNB1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of CTNNB1 protein; Phenobarbital inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CTNNB1 protein]
CTD PMID:14555707, PMID:16878161, PMID:17030184, PMID:17219422, PMID:21472727, PMID:25217643, PMID:26990689, PMID:27693619, PMID:28343033, PMID:28548306, PMID:31115591, PMID:32112862 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cul2 cullin 2 multiple interactions ISO CUL2 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of MAF1 protein] CTD PMID:31645432 NCBI chr17:56,952,480...56,992,716
Ensembl chr17:56,952,480...56,992,694
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CX3CL1 mRNA] CTD PMID:11698246 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL1 protein] CTD PMID:11698246 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CXCL12 mRNA CTD PMID:25566086 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL1 protein] CTD PMID:11698246 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TPD7 compound results in decreased expression of CXCR4 protein] CTD PMID:25753200 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cycs cytochrome c, somatic affects localization EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the localization of CYCS protein CTD PMID:15725397 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
increases activity
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Cycloheximide co-treated with Harmaline] results in decreased expression of CYP1A1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Cycloheximide co-treated with harmalol] results in decreased expression of CYP1A1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Harmine results in decreased stability of CYP1A1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [harmol results in decreased stability of CYP1A1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CYP1A1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CYP1A1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CYP1A1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Cadmium Chloride results in increased expression of CYP1A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Copper results in increased expression of CYP1A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Lead results in increased expression of CYP1A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Mercury results in increased expression of CYP1A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [sodium arsenite results in increased expression of CYP1A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
CTD PMID:10722677, PMID:10777561, PMID:16093525, PMID:16891617, PMID:17606337, PMID:18835339, PMID:22001777, PMID:22037238 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases stability ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of CYP1B1 protein CTD PMID:15486049 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
decreases activity
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP2B1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased activity of CYP2B1 protein
CTD PMID:18835339 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Phenobarbital results in increased expression of CYP2B6 mRNA] CTD PMID:24224465 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dexamethasone results in increased expression of CYP3A23-3A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dexamethasone results in increased expression of CYP3A23-3A1 protein] CTD PMID:17083955 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Ddc dopa decarboxylase decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of DDC mRNA CTD PMID:25566086 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
increases activity
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [1,2-dithiol-3-thione inhibits the reaction [Tunicamycin results in increased expression of DDIT3 mRNA]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DDIT3 mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DDIT3 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of DDIT3 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DDIT3 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DDIT3 protein
CTD PMID:17912641, PMID:19135031, PMID:19139269, PMID:22959925, PMID:23684743, PMID:25566086 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dffa DNA fragmentation factor subunit alpha multiple interactions ISO DFFA protein inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of DFFB protein] CTD PMID:18178165 NCBI chr 5:165,922,893...165,935,822
Ensembl chr 5:165,922,915...165,935,821
JBrowse link
G Dffb DNA fragmentation factor subunit beta multiple interactions
decreases degradation
increases ubiquitination
ISO DFFA protein inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of DFFB protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of DFFB protein
CTD PMID:18178165 NCBI chr 5:171,250,559...171,261,875
Ensembl chr 5:171,249,633...171,262,119
JBrowse link
G Dio2 iodothyronine deiodinase 2 multiple interactions
increases expression
increases activity
ISO
EXP
[Cycloheximide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] inhibits the reaction [2,2',4,4',5-brominated diphenyl ether metabolite results in decreased activity of DIO2 protein]; [Cycloheximide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased activity of DIO2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [2,2',4,4',5-brominated diphenyl ether results in decreased activity of DIO2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased activity of DIO2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Thyroxine results in decreased activity of DIO2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Triiodothyronine, Reverse results in decreased activity of DIO2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and results in increased activity of DIO2 protein; Cycloheximide promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [2,2',4,4',5-brominated diphenyl ether results in decreased activity of DIO2 protein]]; Cycloheximide promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Triiodothyronine, Reverse results in decreased activity of DIO2 protein]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DIO2 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of DIO2 protein
CTD PMID:11425850, PMID:17615150, PMID:26004626 NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DNAJB1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DNAJB1 protein CTD PMID:15525353, PMID:25566086 NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919
JBrowse link
G Dnajc2 DnaJ heat shock protein family (Hsp40) member C2 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DNAJC2 mRNA CTD PMID:25566086 NCBI chr 4:9,881,505...9,908,693
Ensembl chr 4:9,882,904...9,908,689
JBrowse link
G Dnajc7 DnaJ heat shock protein family (Hsp40) member C7 multiple interactions
increases ubiquitination
ISO 1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of DNAJC7 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [DNAJC7 protein results in increased expression of NR1I3 protein]; NR1I3 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of DNAJC7 protein]] CTD PMID:24789201 NCBI chr10:88,498,271...88,533,730
Ensembl chr10:88,498,238...88,533,829
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Benzo(a)pyrene results in increased degradation of DNMT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [quinoline analog results in increased degradation of DNMT1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of DNMT1 protein]
CTD PMID:19417133, PMID:21150308, PMID:23395981 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of DNMT3A protein] CTD PMID:23395981 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of DNMT3B protein] CTD PMID:23395981 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786
JBrowse link
G Dnmt3l DNA methyltransferase 3 like multiple interactions
increases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DNMT3L mRNA] CTD PMID:25566086 NCBI chr20:11,344,513...11,359,090
Ensembl chr20:11,344,514...11,359,090
JBrowse link
G Dpp7 dipeptidylpeptidase 7 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [[DPP7 protein results in increased cleavage of Dipeptides] which results in increased abundance of 4-nitroaniline] CTD PMID:16725115 NCBI chr 3:2,569,135...2,573,387
Ensembl chr 3:2,569,135...2,573,387
JBrowse link
G Dync1h1 dynein cytoplasmic 1 heavy chain 1 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DYNC1H1 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DYNC1H1 mRNA]
CTD PMID:25566086 NCBI chr 6:134,958,854...135,085,769
Ensembl chr 6:134,958,854...135,085,769
JBrowse link
G Dync1i1 dynein cytoplasmic 1 intermediate chain 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DYNC1I1 mRNA CTD PMID:20061341 NCBI chr 4:30,807,755...31,121,097
Ensembl chr 4:30,807,879...31,121,090
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dronabinol results in decreased expression of E2F1 protein] CTD PMID:17934890 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Edn1 endothelin 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EDN1 mRNA CTD PMID:18457675 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Egf epidermal growth factor multiple interactions ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein affects the localization of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased secretion of MUC5AC protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein]]
CTD PMID:22689575, PMID:22766066 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfl7 EGF-like-domain, multiple 7 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of EGFL7 mRNA CTD PMID:25566086 NCBI chr 3:4,034,759...4,044,280
Ensembl chr 3:4,034,921...4,043,936
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [gemcitabine results in increased phosphorylation of and results in increased degradation of EGFR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [MUC1 affects the expression of EGFR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [platycodin D results in decreased expression of EGFR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfide results in decreased expression of EGFR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfone results in decreased expression of EGFR protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EGFR protein
CTD PMID:17146438, PMID:20332299, PMID:22457794, PMID:28711525 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EGLN1 mRNA] CTD PMID:25566086 NCBI chr19:57,660,194...57,701,158
Ensembl chr19:57,662,278...57,699,113
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EGLN3 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EGLN3 mRNA]
CTD PMID:25566086 NCBI chr 6:75,050,329...75,075,795
Ensembl chr 6:75,050,329...75,075,795
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of EIF2AK2 mRNA CTD PMID:25566086 NCBI chr 6:1,428,845...1,466,193
Ensembl chr 6:1,428,834...1,466,201
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [1,2-dithiol-3-thione inhibits the reaction [Tunicamycin results in increased expression of EIF2AK3 mRNA]] CTD PMID:22959925 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation
multiple interactions
increases expression
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of EIF2S1 protein
[XBP1 mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] inhibits the reaction [Tobacco Smoke Pollution analog results in increased phosphorylation of EIF2S1 protein]; PTPN1 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of EIF2S1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EIF2S1 protein modified form
CTD PMID:21090173, PMID:22321511, PMID:23684743, PMID:25568320, PMID:28359145 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium Chloride results in decreased expression of EIF4E protein] CTD PMID:15878868 NCBI chr 2:243,819,616...243,853,987
Ensembl chr 2:243,820,661...243,852,631
JBrowse link
G Elavl1 ELAV like RNA binding protein 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ELAVL1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ELAVL1 protein CTD PMID:23922739 NCBI chr12:2,461,502...2,502,432
Ensembl chr12:2,461,502...2,502,432
JBrowse link
G Emcn endomucin decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EMCN mRNA CTD PMID:25566086 NCBI chr 2:242,634,319...242,715,489
Ensembl chr 2:242,634,399...242,714,182
JBrowse link
G Eno3 enolase 3 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ENO3 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ENO3 mRNA]
CTD PMID:25566086 NCBI chr10:57,278,271...57,283,661
Ensembl chr10:57,278,307...57,283,653
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin affects the localization of EP300 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of EP300 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of EP300 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Doxorubicin results in increased degradation of EP300 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SIRT6 protein results in decreased expression of EP300 protein]
CTD PMID:15767673, PMID:17927689, PMID:27094368 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions
increases stability
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen inhibits the reaction [AQP3 protein results in increased stability of EPAS1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen inhibits the reaction [AQP5 protein results in increased stability of EPAS1 protein]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of EPAS1 protein
CTD PMID:23545307 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Ephb4 EPH receptor B4 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Homoharringtonine results in decreased expression of EPHB4 protein] CTD PMID:31726078 NCBI chr12:22,393,338...22,418,332
Ensembl chr12:22,393,330...22,417,980
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EPHX1 mRNA CTD PMID:20061341 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Ephx2 epoxide hydrolase 2 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EPHX2 mRNA CTD PMID:20061341 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Epo erythropoietin multiple interactions
increases expression
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [methylmercuric chloride results in decreased expression of EPO protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Methylmercury Compounds results in decreased expression of EPO protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EPO protein
CTD PMID:31850806, PMID:32461003 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Eppk1 epiplakin 1 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EPPK1 mRNA CTD PMID:25566086 NCBI chr 7:117,163,383...117,173,741 JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ERBB2 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Quercetin results in decreased expression of ERBB2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfide results in decreased expression of ERBB2 protein]
CTD PMID:18655187, PMID:20332299 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 multiple interactions
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfide results in decreased expression of ERBB3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfone results in decreased expression of ERBB3 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ERBB3 protein
CTD PMID:20332299 NCBI chr 7:2,989,202...3,010,610
Ensembl chr 7:2,989,340...3,010,350
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ERCC6 gene mutant form results in decreased expression of SIRT1 protein] CTD PMID:25440059 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ERN1 protein CTD PMID:19139269 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases expression
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Butyrophenones results in increased degradation of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Carbamazepine results in decreased expression of ESR1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Carbamazepine results in decreased expression of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Estradiol inhibits the reaction [ESR1 protein binds to GSK3B protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Okadaic Acid results in increased degradation of ESR1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [resveratrol results in increased degradation of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of ESR1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [fulvestrant results in increased degradation of ESR1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ESR1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Estradiol results in decreased expression of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Gonadotropin-Releasing Hormone results in decreased expression of ESR1 protein]
CTD PMID:12612060, PMID:14702340, PMID:14750165, PMID:15965230, PMID:16055746, PMID:16965676, PMID:20419096, PMID:21041310, PMID:26990689 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
increases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ESR2 protein
CTD PMID:14702340, PMID:15207704 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Fahd1 fumarylacetoacetate hydrolase domain containing 1 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of FAHD1 mRNA CTD PMID:25566086 NCBI chr10:14,214,518...14,215,957
Ensembl chr10:14,214,519...14,215,957
JBrowse link
G Fam13b family with sequence similarity 13, member B multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of FAM13B mRNA CTD PMID:25566086 NCBI chr18:27,223,345...27,304,462
Ensembl chr18:27,223,345...27,289,876
JBrowse link
G Fam78a family with sequence similarity 78, member A decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of FAM78A mRNA CTD PMID:25566086 NCBI chr 3:11,086,016...11,105,151
Ensembl chr 3:11,087,299...11,102,515
JBrowse link
G Faslg Fas ligand multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [evodiamine results in increased expression of FASLG protein] CTD PMID:20005289 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fbxl12 F-box and leucine-rich repeat protein 12 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of FBXL12 mRNA CTD PMID:20061341 NCBI chr 8:21,656,636...21,662,755
Ensembl chr 8:21,656,639...21,661,259
JBrowse link
G Fbxo10 F-box protein 10 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of FBXO10 mRNA] CTD PMID:25566086 NCBI chr 5:60,589,881...60,636,551
Ensembl chr 5:60,591,023...60,658,564
JBrowse link
G Fbxo2 F-box protein 2 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of FBXO2 mRNA CTD PMID:25566086 NCBI chr 5:164,972,483...164,977,912
Ensembl chr 5:164,972,480...164,977,916
JBrowse link
G Fbxo32 F-box protein 32 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [FBXO32 protein results in decreased expression of KCNN2 protein] CTD PMID:30635400 NCBI chr 7:98,065,664...98,098,071
Ensembl chr 7:98,063,735...98,098,268
JBrowse link
G Fbxo6 F-box protein 6 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of FBXO6 mRNA CTD PMID:20061341 NCBI chr 5:164,956,285...164,962,075
Ensembl chr 5:164,956,280...164,959,851
JBrowse link
G Fhl2 four and a half LIM domains 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of FHL2 mRNA CTD PMID:25566086 NCBI chr 9:49,920,611...49,994,906
Ensembl chr 9:49,920,854...49,950,093
JBrowse link
G Flnc filamin C increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of FLNC mRNA CTD PMID:25566086 NCBI chr 4:56,710,934...56,738,779
Ensembl chr 4:56,711,049...56,738,791
JBrowse link
G Fn1 fibronectin 1 decreases secretion ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased secretion of FN1 protein CTD PMID:11594554 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Hydrogen Peroxide results in increased expression of FOS protein]
[Arachidonic Acid co-treated with Quercetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of FOS protein
CTD PMID:15136564, PMID:20551291 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein]] CTD PMID:17148446 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Foxm1 forkhead box M1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [palbociclib results in decreased expression of FOXM1 protein] CTD PMID:22094256 NCBI chr 4:161,685,236...161,697,633
Ensembl chr 4:161,685,258...161,696,305
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [dorsomorphin results in decreased expression of FOXO1 protein] CTD PMID:25065674 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide results in increased expression of FOXO3 protein] CTD PMID:31421153 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Fsd2 fibronectin type III and SPRY domain containing 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of FSD2 mRNA CTD PMID:25566086 NCBI chr 1:143,364,867...143,398,123
Ensembl chr 1:143,364,867...143,398,093
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in increased degradation of and results in decreased expression of FTH1 protein] CTD PMID:16707465 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Ftl1 ferritin light chain 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in increased degradation of and results in decreased expression of FTL protein] CTD PMID:16707465 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Fundc1 FUN14 domain containing 1 multiple interactions
increases expression
ISO [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Rotenone] results in increased expression of FUNDC1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Rotenone results in decreased expression of FUNDC1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of FUNDC1 protein
CTD PMID:32001317 NCBI chr  X:5,549,468...5,566,125
Ensembl chr  X:5,549,419...5,566,127
JBrowse link
G G0s2 G0/G1switch 2 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of G0S2 mRNA CTD PMID:25566086 NCBI chr13:112,004,140...112,005,052
Ensembl chr13:112,004,140...112,005,052
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction and affects the localization of [PSMC5 protein binds to GABBR2 protein] CTD PMID:24482233 NCBI chr 5:62,276,100...62,621,737
Ensembl chr 5:62,276,100...62,621,737
JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen deficiency results in decreased expression of GAD1 protein] CTD PMID:29107683 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gad2 glutamate decarboxylase 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen deficiency results in decreased expression of GAD2 protein] CTD PMID:29107683 NCBI chr17:89,171,576...89,234,770
Ensembl chr17:89,171,250...89,238,040
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GADD45A mRNA CTD PMID:20061341, PMID:25566086 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of GADD45G mRNA CTD PMID:25566086 NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of GCLC mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of GCLC protein] CTD PMID:25263748 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GCLM mRNA CTD PMID:20061341 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions
increases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GDF15 mRNA] CTD PMID:25566086 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [antofine results in decreased expression of GJA1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ioxynil analog results in decreased expression of GJA1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ioxynil results in decreased expression of GJA1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GJA1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [fulvestrant results in decreased expression of GJA1 protein]
CTD PMID:15685554, PMID:20510257, PMID:23403203, PMID:29180066 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gja5 gap junction protein, alpha 5 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GJA5 mRNA CTD PMID:25566086 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939
JBrowse link
G Gls glutaminase multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diphenylarsinic acid results in increased degradation of GLS protein alternative form] CTD PMID:22493432 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Gpr146 G protein-coupled receptor 146 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of GPR146 mRNA CTD PMID:25566086 NCBI chr12:17,343,396...17,358,631
Ensembl chr12:17,345,510...17,358,617
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 increases localization EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased localization of GRIA1 protein CTD PMID:19674091 NCBI chr10:42,441,723...42,760,200
Ensembl chr10:42,614,713...42,760,200
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 increases localization EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased localization of GRIA2 protein CTD PMID:19674091 NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629
JBrowse link
G Grip1 glutamate receptor interacting protein 1 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GRIP1 mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [GRIP1 protein binds to NR1I3 protein]
CTD PMID:24224465, PMID:25566086 NCBI chr 7:64,672,723...64,854,939
Ensembl chr 7:64,672,722...64,864,404
JBrowse link
G Gsg1l GSG1-like multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GSG1L mRNA] CTD PMID:25566086 NCBI chr 1:197,271,704...197,482,776 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Estradiol inhibits the reaction [ESR1 protein binds to GSK3B protein]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of GSK3B protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GSK3B protein modified form
CTD PMID:24085292, PMID:26990689, PMID:30703377 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSR mRNA CTD PMID:20061341 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gss glutathione synthetase increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSS mRNA CTD PMID:20061341 NCBI chr 3:151,076,254...151,106,557
Ensembl chr 3:151,076,254...151,106,557
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTA2 mRNA CTD PMID:12446695, PMID:20061341 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTA3 mRNA CTD PMID:20061341 NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Lead results in increased expression of GSTA1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Mercury results in increased expression of GSTA1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTA1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide promotes the reaction [Copper results in decreased expression of GSTA1 mRNA]] CTD PMID:16243960 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
JBrowse link
G Gsta6 glutathione S-transferase alpha 6 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTA2 mRNA CTD PMID:20061341 NCBI chr 9:27,475,273...27,533,939
Ensembl chr 9:27,475,273...27,511,176
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTM1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTM5 mRNA CTD PMID:20061341 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTM2 mRNA CTD PMID:20061341 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTM3 mRNA CTD PMID:20061341 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTP1 protein CTD PMID:15863507 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GUCY1A1 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GUCY1A1 mRNA]
CTD PMID:25566086 NCBI chr 2:181,045,694...181,103,321
Ensembl chr 2:181,045,703...181,102,918
JBrowse link
G Gyg1 glycogenin 1 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GYG mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GYG mRNA]
CTD PMID:25566086 NCBI chr 2:104,916,734...104,958,219
Ensembl chr 2:104,916,738...104,958,034
JBrowse link
G H2ac12 H2A clustered histone 12 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC12 mRNA CTD PMID:25566086 NCBI chr17:44,527,990...44,528,557
Ensembl chr17:44,528,125...44,528,511
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [veliparib promotes the reaction [Camptothecin results in increased expression of H2AX protein]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Doxorubicin results in increased expression of H2AX protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Etoposide results in increased expression of H2AX protein]
CTD PMID:17875725, PMID:21227924 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Haghl hydroxyacylglutathione hydrolase-like multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of HAGHL mRNA CTD PMID:25566086 NCBI chr10:15,152,736...15,157,221
Ensembl chr10:15,152,709...15,155,412
JBrowse link
G Hax1 HCLS1 associated protein X-1 affects expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the expression of HAX1 protein CTD PMID:19763263 NCBI chr 2:189,330,900...189,333,305
Ensembl chr 2:189,330,902...189,333,322
JBrowse link
G Hdac1 histone deacetylase 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin affects the localization of HDAC1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of HDAC1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of HDAC1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Particulate Matter results in increased degradation of HDAC1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Vehicle Emissions results in increased degradation of HDAC1 protein] CTD PMID:17395887, PMID:17927689 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hdac2 histone deacetylase 2 increases ubiquitination
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of HDAC2 protein
[SOD2 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of HDAC2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Smoke results in increased degradation of and results in decreased expression of HDAC2 protein]; CAT protein inhibits the reaction [[SOD2 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of HDAC2 protein]
CTD PMID:18421014, PMID:24973648 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HES1 mRNA] CTD PMID:25566086 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases degradation
multiple interactions
increases expression
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of HIF1A protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [methylmercuric chloride results in decreased expression of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Methylmercury Compounds results in decreased expression of HIF1A protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein modified form
15,16-dihydrotanshinone I inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; 3-(4-bromophenyl)-2-(ethylsulfonyl)-6-methylquinoxaline-1,4-dioxide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; [andrographolide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of HIF1A protein; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]; [Oxygen deficiency co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the expression of HIF1A protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [andrographolide results in decreased expression of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [andrographolide results in increased degradation of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in increased degradation of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [geldanamycin results in increased degradation of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [L-4F peptide inhibits the reaction [INS protein results in increased expression of HIF1A protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [MALAT1 mRNA affects the reaction [sodium arsenite results in increased expression of HIF1A protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [scutellarin results in decreased expression of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [[Dinoprostone binds to and results in increased activity of PTGER1 protein] which results in increased expression of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HIF1A protein binds to VHL protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [VHL protein binds to HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of HIF1A protein; Curcumin analog inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; Curcumin analog inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein modified form]; diallyl trisulfide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of HIF1A protein]; dictamnine inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; genipin affects the reaction [[Oxygen deficiency co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the expression of HIF1A protein]; Glucosamine affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein]; manganese chloride inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HIF1A protein binds to VHL protein]]; Resveratrol inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [resveratrol results in decreased expression of HIF1A protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein]
CTD PMID:11980636, PMID:17764071, PMID:17973296, PMID:18682687, PMID:19254699, PMID:19263519, PMID:20335389, PMID:20524035, PMID:20554536, PMID:21134392, PMID:22537771, PMID:23593480, PMID:24221993, PMID:24497960, PMID:24975222, PMID:25192544, PMID:26282490, PMID:27287256, PMID:28574600, PMID:28651835, PMID:29630948, PMID:30266538, PMID:31850806, PMID:32461003 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Higd1b HIG1 hypoxia inducible domain family, member 1B decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HIGD1B mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HIGD1B mRNA]
CTD PMID:25566086 NCBI chr10:90,929,362...90,931,639
Ensembl chr10:90,929,423...90,931,639
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [cobaltous chloride results in decreased expression of HIPK2 protein] CTD PMID:19714248 NCBI chr 4:66,438,390...66,625,183
Ensembl chr 4:66,445,266...66,624,912
JBrowse link
G Hist1h2af histone cluster 1 H2A family member F multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC15 mRNA CTD PMID:25566086 NCBI chr17:43,627,237...43,627,629
Ensembl chr17:43,627,237...43,627,629
JBrowse link
G Hist1h2ah histone cluster 1 H2A family member H multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC22 mRNA CTD PMID:25566086 NCBI chr17:43,632,354...43,632,851
Ensembl chr17:44,747,796...44,748,188
Ensembl chr17:44,747,796...44,748,188
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HMOX1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HMOX1 protein
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in decreased expression of HMOX1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Hemin results in increased expression of HMOX1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Hemin results in decreased expression of HMOX1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Hemin results in increased expression of HMOX1 mRNA]; HMOX1 protein inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HMOX1 protein]; HMOX1 protein promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HMOX1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of HMOX1 mRNA]
CTD PMID:12441344, PMID:18550526, PMID:18835339, PMID:25824035 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Thapsigargin affects the localization of HNRNPA1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tunicamycin affects the localization of HNRNPA1 protein] CTD PMID:23106379 NCBI chr 7:144,865,302...144,871,592
Ensembl chr 7:144,865,608...144,871,585
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NSC606985 results in decreased expression of HNRNPK protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [PRKCD protein results in increased ubiquitination of HNRNPK protein] CTD PMID:19747914 NCBI chr17:6,664,730...6,676,753
Ensembl chr17:6,665,659...6,676,654
JBrowse link
G Hopx HOP homeobox multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of HOPX mRNA CTD PMID:25566086 NCBI chr14:33,354,803...33,362,547
Ensembl chr14:33,354,807...33,362,551
JBrowse link
G Hp haptoglobin decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HP mRNA CTD PMID:20061341 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hr HR, lysine demethylase and nuclear receptor corepressor multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HR mRNA] CTD PMID:25566086 NCBI chr15:52,241,801...52,261,276
Ensembl chr15:52,241,801...52,261,276
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Progesterone results in increased expression of HSD11B2 mRNA] CTD PMID:15857753 NCBI chr19:37,476,083...37,481,326
Ensembl chr19:37,476,095...37,481,307
JBrowse link
G Hsf1 heat shock transcription factor 1 increases activity ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of HSF1 protein CTD PMID:11893605 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hsf2 heat shock transcription factor 2 increases activity
increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of HSF2 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSF2 protein
Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSF2 protein]
CTD PMID:11893605, PMID:15914627 NCBI chr20:38,935,820...38,963,444
Ensembl chr20:38,935,820...38,963,309
JBrowse link
G Hsf4 heat shock transcription factor 4 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSF4 protein
Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSF4 protein]
CTD PMID:15914627 NCBI chr19:37,225,800...37,232,048
Ensembl chr19:37,226,186...37,231,912
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSP90AA1 mRNA CTD PMID:25566086 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions
increases expression
EXP
ISO
PARK7 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA1A protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA1A mRNA
CTD PMID:18331584, PMID:25566086 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA1B mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA1B protein CTD PMID:15525353, PMID:25566086 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 multiple interactions
increases expression
ISO Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA4 protein] CTD PMID:15914627 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA5 protein CTD PMID:19139269, PMID:21692457 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of HSPA8 mRNA CTD PMID:25566086 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPB1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPB1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [bufalin results in decreased expression of HSPB1 protein]
Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPB1 protein]
CTD PMID:15914627, PMID:23091618 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hspb2 heat shock protein family B (small) member 2 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HSPB2 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HSPB2 mRNA]
CTD PMID:25566086 NCBI chr 8:55,176,648...55,178,227
Ensembl chr 8:55,176,847...55,177,818
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPH1 mRNA CTD PMID:25566086 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Htra2 HtrA serine peptidase 2 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HTRA2 protein CTD PMID:19763263 NCBI chr 4:113,883,671...113,886,833
Ensembl chr 4:113,883,670...113,886,994
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:11698246, PMID:14572618 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifng interferon gamma multiple interactions ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP6 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP8 protein]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP1 protein]]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP6 protein]]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP8 protein]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]
CTD PMID:15914627, PMID:19393675, PMID:23395999 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1r insulin-like growth factor 1 receptor multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [platycodin D results in decreased expression of IGF1R protein] CTD PMID:28711525 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igf2 insulin-like growth factor 2 multiple interactions
decreases response to substance
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IGF2 protein results in increased expression of STS mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IGF2 protein results in increased expression of STS protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased susceptibility to IGF2 protein
CTD PMID:24055520 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Il18 interleukin 18 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Isoproterenol results in increased secretion of IL18 protein] CTD PMID:15178407 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1a interleukin 1 alpha multiple interactions
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of IL1A mRNA
CTD PMID:11230753, PMID:15728660, PMID:20061341 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases response to substance
ISO
EXP
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with IL1B protein] results in increased expression of and results in increased phosphorylation of NFKBIA protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; sodium arsenite inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with IL1B protein] results in increased expression of and results in increased phosphorylation of NFKBIA protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased susceptibility to IL1B protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA]
CTD PMID:10541287, PMID:11835394, PMID:14581482, PMID:19393675, PMID:23395999 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of IL6 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of IL6 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Chloroquine co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL6 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL6 protein]
Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of IL6 protein]
CTD PMID:11893605, PMID:18457675, PMID:28134560 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Impact impact RWD domain protein increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of IMPACT mRNA CTD PMID:25566086 NCBI chr18:4,325,872...4,346,734
Ensembl chr18:4,325,875...4,346,769
JBrowse link
G Inafm2 InaF motif containing 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of INAFM2 mRNA CTD PMID:25566086 NCBI chr 3:110,540,349...110,545,882 JBrowse link
G Ins2 insulin 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [L-4F peptide inhibits the reaction [INS protein results in increased expression of HIF1A protein]] CTD PMID:22537771 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Insl6 insulin-like 6 multiple interactions
increases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of INSL6 mRNA] CTD PMID:25566086 NCBI chr 1:247,473,292...247,476,827
Ensembl chr 1:247,473,292...247,476,827
JBrowse link
G Irf8 interferon regulatory factor 8 decreases degradation ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of IRF8 protein CTD PMID:15837792 NCBI chr19:54,314,859...54,336,643
Ensembl chr19:54,314,865...54,336,640
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [INS1 protein results in decreased expression of IRS1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [triptolide results in decreased expression of IRS1 protein] CTD PMID:24219910, PMID:32061799 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Irx3 iroquois homeobox 3 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of IRX3 mRNA CTD PMID:25566086 NCBI chr19:15,838,714...15,842,135
Ensembl chr19:15,838,714...15,840,990
JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tretinoin results in increased expression of ITGAM protein] CTD PMID:20945414 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Itgb1bp2 integrin subunit beta 1 binding protein 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ITGB1BP2 mRNA CTD PMID:25566086 NCBI chr  X:71,342,770...71,347,623
Ensembl chr  X:71,342,775...71,347,619
JBrowse link
G Ivl involucrin increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of IVL mRNA CTD PMID:25566086 NCBI chr 2:192,761,171...192,773,346
Ensembl chr 2:192,761,538...192,763,577
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of JUN protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [KU-32 compound inhibits the reaction [NRG1 protein results in increased expression of and results in increased phosphorylation of JUN protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NRG1 protein results in increased expression of and results in increased phosphorylation of JUN protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of JUN protein]
CTD PMID:23240583, PMID:23593480 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB protein]] CTD PMID:17148446 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Kat5 lysine acetyltransferase 5 multiple interactions
increases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [KAT5 protein results in increased acetylation of and results in increased degradation of SRSF2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in decreased expression of KAT5 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of KAT5 protein
CTD PMID:21157427, PMID:28837777 NCBI chr 1:220,967,795...220,974,596
Ensembl chr 1:220,967,796...220,974,597
JBrowse link
G Katnb1 katanin regulatory subunit B1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of KATNB1 mRNA CTD PMID:25566086 NCBI chr19:10,340,027...10,360,319
Ensembl chr19:10,340,307...10,360,310
JBrowse link
G Kbtbd11 kelch repeat and BTB domain containing 11 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of KBTBD11 mRNA CTD PMID:25566086 NCBI chr16:79,696,395...79,716,129
Ensembl chr16:79,696,891...79,700,992
JBrowse link
G Kcng2 potassium voltage-gated channel modifier subfamily G member 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of KCNG2 mRNA CTD PMID:25566086 NCBI chr18:76,808,294...76,880,742
Ensembl chr18:76,809,144...76,878,981
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [arsenic trioxide results in increased degradation of KCNH2 protein] CTD PMID:28521025 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Kcnip3 potassium voltage-gated channel interacting protein 3 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[SOD1 protein results in increased susceptibility to Thimerosal] which results in decreased expression of KCNIP3 protein] CTD PMID:30503815 NCBI chr 3:120,023,062...120,087,650
Ensembl chr 3:120,023,917...120,087,136
JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [FBXO32 protein results in decreased expression of KCNN2 protein] CTD PMID:30635400 NCBI chr18:39,331,894...39,479,574
Ensembl chr18:39,335,377...39,479,257
JBrowse link
G Kdm1a lysine demethylase 1A multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SP2509 results in decreased stability of KDM1A protein] CTD PMID:29581250 NCBI chr 5:154,909,003...154,965,171
Ensembl chr 5:154,909,003...154,965,171
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO [2-tert-butylhydroquinone co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NFE2L2 protein binds to KEAP1 protein] CTD PMID:18512965 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Kif1a kinesin family member 1A increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of KIF1A mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of KIF1A mRNA]
CTD PMID:25566086 NCBI chr 9:100,171,851...100,253,626
Ensembl chr 9:100,171,772...100,253,609
JBrowse link
G Kif1b kinesin family member 1B increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of KIF1B mRNA CTD PMID:25566086 NCBI chr 5:165,994,803...166,133,497
Ensembl chr 5:165,938,576...166,133,491
JBrowse link
G Kif20a kinesin family member 20A decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of KIF20A mRNA CTD PMID:20061341 NCBI chr18:27,424,328...27,432,814
Ensembl chr18:27,424,328...27,432,814
JBrowse link
G Kif4a kinesin family member 4A decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of KIF4 mRNA CTD PMID:20061341 NCBI chr  X:70,461,700...70,561,084
Ensembl chr  X:70,461,718...70,561,189
JBrowse link
G Klhl6 kelch-like family member 6 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of KLHL6 mRNA] CTD PMID:25566086 NCBI chr11:84,745,958...84,785,315
Ensembl chr11:84,745,904...84,785,893
JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding protein decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of KNSTRN mRNA CTD PMID:20061341 NCBI chr 3:110,618,256...110,638,024
Ensembl chr 3:110,618,298...110,638,046
JBrowse link
G Krt5 keratin 5 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [Diacetyl affects the expression of and affects the ubiquitination of KRT5 protein] CTD PMID:32112875 NCBI chr 7:143,320,142...143,324,536
Ensembl chr 7:143,316,920...143,453,546
JBrowse link
G Ky kyphoscoliosis peptidase multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of KY mRNA CTD PMID:25566086 NCBI chr 8:110,982,777...111,022,666
Ensembl chr 8:110,982,777...111,022,385
JBrowse link
G Lat2 linker for activation of T cells family, member 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [10-(octyloxy)decyl-2-(trimethylammonium)ethyl phosphate results in decreased expression of LAT2 protein] CTD PMID:23001822 NCBI chr12:25,114,099...25,128,381
Ensembl chr12:25,119,355...25,125,749
JBrowse link
G Ldb3 LIM domain binding 3 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LDB3 mRNA] CTD PMID:25566086 NCBI chr16:10,878,348...10,943,016
Ensembl chr16:10,878,334...10,941,501
JBrowse link
G Lgals1 galectin 1 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of LGALS1 mRNA CTD PMID:25566086 NCBI chr 7:120,153,184...120,156,290
Ensembl chr 7:120,153,184...120,156,289
JBrowse link
G Lmo7 LIM domain 7 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LMO7 mRNA] CTD PMID:25566086 NCBI chr15:86,242,911...86,458,512
Ensembl chr15:86,243,148...86,457,739
JBrowse link
G Lnx1 ligand of numb-protein X 1 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LNX1 mRNA CTD PMID:20061341 NCBI chr14:36,047,136...36,149,740
Ensembl chr14:36,047,144...36,149,740
JBrowse link
G LOC102550598 small proline-rich protein 2I-like multiple interactions
increases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SPRR2G mRNA] CTD PMID:25566086 NCBI chr 2:192,520,019...192,521,188
Ensembl chr 2:192,520,733...192,520,960
JBrowse link
G LOC103689977 caspase-6 multiple interactions
decreases activity
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP6 protein]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP6 protein]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased activity of CASP6 protein
CTD PMID:15914627 NCBI chr 2:230,186,170...230,198,555
Ensembl chr 2:230,186,198...230,198,555
JBrowse link
G Lpin1 lipin 1 multiple interactions
increases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TGFB1 protein results in decreased expression of LPIN1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of LPIN1 protein
CTD PMID:27345520 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046
JBrowse link
G Lrrc10 leucine-rich repeat-containing 10 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LRRC10 mRNA
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of LRRC10 mRNA; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LRRC10 mRNA]
CTD PMID:25566086 NCBI chr 7:60,087,361...60,088,758
Ensembl chr 7:60,087,429...60,088,250
JBrowse link
G Lrrc75a leucine rich repeat containing 75A multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of LRRC75A mRNA CTD PMID:25566086 NCBI chr10:48,929,519...48,947,606
Ensembl chr10:48,930,416...48,944,304
JBrowse link
G Luc7l LUC7-like multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of LUC7L mRNA CTD PMID:25566086 NCBI chr10:15,538,878...15,572,651
Ensembl chr10:15,538,872...15,568,638
JBrowse link
G Lxn latexin decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LXN mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LXN mRNA]
CTD PMID:25566086 NCBI chr 2:164,628,565...164,634,434
Ensembl chr 2:164,628,566...164,634,434
JBrowse link
G Maf1 MAF1 homolog, negative regulator of RNA polymerase III multiple interactions ISO [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Sirolimus] results in decreased degradation of MAF1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of and results in decreased degradation of MAF1 protein; CUL2 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of MAF1 protein] CTD PMID:31645432 NCBI chr 7:117,417,643...117,420,722
Ensembl chr 7:117,417,687...117,420,719
JBrowse link
G Map1b microtubule-associated protein 1B increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MAP1B mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MAP1B mRNA]
CTD PMID:25566086 NCBI chr 2:29,675,391...29,768,750
Ensembl chr 2:29,675,391...29,768,750
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MAP1LC3B protein modified form
MAP1LC3B protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of NFKBIA protein]
CTD PMID:24085292, PMID:26409479 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:25780039 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:25780039 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
decreases response to substance
multiple interactions
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of MAPK8 protein
MAPK8 gene mutant form results in decreased susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde
MAPK8 affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PMAIP1 mRNA]
CTD PMID:18463101, PMID:23593480 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO MAPK9 inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PMAIP1 mRNA] CTD PMID:23593480 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Marchf6 membrane associated ring-CH-type finger 6 increases stability ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of MARCHF6 protein CTD PMID:30545937 NCBI chr 2:84,533,546...84,608,743
Ensembl chr 2:84,536,669...84,608,712
JBrowse link
G Masp1 mannan-binding lectin serine peptidase 1 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MASP1 mRNA CTD PMID:25566086 NCBI chr11:80,736,424...80,806,278
Ensembl chr11:80,736,576...80,803,382
JBrowse link
G Mb myoglobin decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MB mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MB mRNA]
CTD PMID:25566086 NCBI chr 7:118,101,633...118,108,864
Ensembl chr 7:118,101,634...118,108,864
JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of MBD2 protein] CTD PMID:23395981 NCBI chr18:65,814,026...65,885,115
Ensembl chr18:65,814,026...65,885,114
JBrowse link
G Mbd3 methyl-CpG binding domain protein 3 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of MBD3 protein] CTD PMID:23395981 NCBI chr 7:12,179,046...12,186,251
Ensembl chr 7:12,179,203...12,186,656
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions
increases expression
decreases degradation
increases ubiquitination
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Resveratrol co-treated with Clofarabine] results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Sorafenib co-treated with PRKN protein] results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide promotes the reaction [Ethacrynic Acid results in decreased expression of MCL1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [arsenite results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Clofarabine promotes the reaction [Resveratrol results in decreased expression of MCL1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Quercetin results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Resveratrol promotes the reaction [Clofarabine results in decreased expression of MCL1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [[Resveratrol co-treated with Clofarabine] results in increased expression of MCL1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MCL1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of MCL1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of MCL1 protein
CTD PMID:16109713, PMID:17553788, PMID:20802529, PMID:21750559, PMID:21933852, PMID:23082001, PMID:23341456, PMID:23353698, PMID:24924397, PMID:25408576, PMID:28673964, PMID:32305283 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mcm5 minichromosome maintenance complex component 5 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MCM5 mRNA CTD PMID:25566086 NCBI chr19:14,523,482...14,561,281
Ensembl chr19:14,523,554...14,561,278
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MDM2 mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]]
CTD PMID:17575151, PMID:20061341 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mecp2 methyl CpG binding protein 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of MECP2 protein] CTD PMID:23395981 NCBI chr  X:156,650,389...156,713,813
Ensembl chr  X:156,655,960...156,705,233
JBrowse link
G Mgarp mitochondria-localized glutamic acid-rich protein decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MGARP mRNA CTD PMID:25566086 NCBI chr 2:140,444,963...140,453,719
Ensembl chr 2:140,444,965...140,453,107
JBrowse link
G Mgll monoglyceride lipase decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MGLL mRNA CTD PMID:25566086 NCBI chr 4:120,671,436...120,773,458
Ensembl chr 4:120,671,489...120,771,088
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tamoxifen results in increased degradation of MGMT protein] CTD PMID:17597106 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MGST1 mRNA CTD PMID:20061341 NCBI chr 4:172,119,382...172,134,609
Ensembl chr 4:172,119,331...172,134,607
JBrowse link
G Mir146a microRNA 146a decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MIR146A CTD PMID:32392329 NCBI chr10:28,962,476...28,962,570
Ensembl chr10:28,962,476...28,962,570
JBrowse link
G Mitf melanocyte inducing transcription factor multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Phytol inhibits the reaction [alpha-MSH results in increased expression of MITF protein]] which results in decreased ubiquitination of MITF protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Phytol inhibits the reaction [alpha-MSH results in increased expression of MITF protein]] which results in decreased ubiquitination of MITF protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Phytol inhibits the reaction [alpha-MSH results in increased expression of MITF protein]] CTD PMID:29486182 NCBI chr 4:130,172,484...130,425,496
Ensembl chr 4:130,172,727...130,425,532
JBrowse link
G Mlkl mixed lineage kinase domain like pseudokinase increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MLKL mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MLKL mRNA]
CTD PMID:25566086 NCBI chr19:43,508,416...43,535,050
Ensembl chr19:43,506,976...43,528,851
JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MLLT11 mRNA CTD PMID:25566086 NCBI chr 2:196,392,936...196,402,106
Ensembl chr 2:196,392,938...196,402,106
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [halofuginone results in increased expression of MMP13 mRNA] CTD PMID:16489207 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp23 matrix metallopeptidase 23 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MMP23 mRNA CTD PMID:25566086 NCBI chr 5:173,078,811...173,082,834
Ensembl chr 5:173,078,590...173,081,839
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased activity of MMP9 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [butein results in decreased expression of MMP9 protein] CTD PMID:15728660, PMID:20696233, PMID:24613819 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mocos molybdenum cofactor sulfurase increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MOCOS mRNA CTD PMID:20061341, PMID:25566086 NCBI chr18:16,590,086...16,636,312
Ensembl chr18:16,590,197...16,636,084
JBrowse link
G Mocs1 molybdenum cofactor synthesis 1 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MOCS1 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MOCS1 mRNA]
CTD PMID:25566086 NCBI chr 9:13,493,705...13,513,972
Ensembl chr 9:13,493,709...13,513,960
JBrowse link
G Mocs2 molybdenum cofactor synthesis 2 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MOCS2 mRNA CTD PMID:25566086 NCBI chr 2:46,980,964...46,992,886
Ensembl chr 2:46,980,976...46,992,883
JBrowse link
G Mt3 metallothionein 3 multiple interactions
increases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MT3 mRNA] CTD PMID:25566086 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [arsenic trioxide results in increased degradation of MTHFD1 protein] CTD PMID:28265077 NCBI chr 6:99,282,850...99,350,367
Ensembl chr 6:99,282,850...99,350,340
JBrowse link
G Mtor mechanistic target of rapamycin kinase increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MTOR protein CTD PMID:25897075 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Mtus1 microtubule associated scaffold protein 1 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MTUS1 mRNA CTD PMID:25566086 NCBI chr16:54,240,892...54,386,131
Ensembl chr16:54,291,251...54,386,129
JBrowse link
G Muc1 mucin 1, cell surface associated multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [MUC1 affects the expression of EGFR protein] CTD PMID:22457794 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased secretion of MUC5AC protein] CTD PMID:22766066 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Mybpc3 myosin binding protein C3 decreases expression
affects response to substance
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYBPC3 mRNA
MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of BOK mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CAV1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CCNB1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CDH3 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CDK1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CKB mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of EGFL7 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of FAHD1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of G0S2 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of GPR146 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC10 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC12 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC13 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC15 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC22 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC7 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of HAGHL mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of HOPX mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of KBTBD11 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of KY mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of LGALS1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of LRRC10 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of LRRC75A mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MCM5 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MMP23 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MYL12B mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MYLK mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of NRM mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PBK mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PDLIM4 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PLEKHG2 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PLK1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PPARGC1B mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PPP1R3G mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of ROBO4 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of RRM2 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of SYNPO mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TK1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TMEM176A mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TMEM176B mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TRIB2 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of ZFYVE21 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of ATG12 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of EIF2AK2 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of FAM13B mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of GADD45G mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of HSPA8 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of LUC7L mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of NRIP3 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of SF1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of SWT1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of UFD1 mRNA; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACAA2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACTC1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ADSSL1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of APH1A mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ARG1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ART3 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of C1QB mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CAR14 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CAVIN1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CENPA mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CHRM2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CKMT2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CLIP4 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CMYA5 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CORIN mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EGLN1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EGLN3 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ENO3 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of FBXO10 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GSG1L mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GUCY1A1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GYG mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of H2-AB1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HES1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HIGD1B mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HR mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HSPB2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of KLHL6 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LDB3 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LMO7 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LRRC10 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LXN mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MB mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYBPC3 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYBPHL mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYL1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYL7 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYO5B mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYZAP mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NACAD mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NIPSNAP2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NMRK2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PCDH7 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDK1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDLIM5 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PERM1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PFKP mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PIP5K1B mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PLAC8 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PPP1R14C mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PRC1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RARRES2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SH3KBP1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SNRK mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SPON2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SPSB4 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SSPN mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TFRC mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of THY1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TMEM204 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TMOD1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TNNI2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TRIL mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TSC22D4 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of UNC13C mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ZBTB8B mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CD14 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CLDN4 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DNMT3L mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DYNC1H1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GDF15 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of INSL6 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of KIF1A mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MAP1B mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MLKL mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MOCS1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MT3 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NGF mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PDPN mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC6A9 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SPRR2G mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SYBU mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TENM4 mRNA]
CTD PMID:25566086 NCBI chr 3:79,940,509...79,958,731
Ensembl chr 3:79,940,561...79,958,730
JBrowse link
G Mybphl myosin binding protein H-like decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYBPHL mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYBPHL mRNA]
CTD PMID:25566086 NCBI chr 2:211,158,902...211,173,036
Ensembl chr 2:211,159,062...211,173,786
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
increases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [5-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one inhibits the reaction [STK11 mutant form results in increased expression of MYC protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in decreased expression of MYC protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Drugs, Chinese Herbal results in decreased expression of MYC protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [nickel sulfate results in increased degradation of MYC protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tretinoin results in decreased expression of MYC protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MYC protein
Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MYC protein]
CTD PMID:20046830, PMID:20945414, PMID:21472727, PMID:23593480, PMID:24793789, PMID:25897075, PMID:28548306 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myh6 myosin heavy chain 6 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYH6 mRNA CTD PMID:25566086 NCBI chr15:33,605,653...33,629,730
Ensembl chr15:33,605,654...33,629,699
JBrowse link
G Myl1 myosin, light chain 1 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYL1 mRNA] CTD PMID:25566086 NCBI chr 9:73,937,820...73,958,480
Ensembl chr 9:73,937,823...73,958,480
JBrowse link
G Myl12b myosin light chain 12B multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MYL12B mRNA CTD PMID:25566086 NCBI chr 9:119,307,168...119,321,500
Ensembl chr 9:119,307,176...119,321,500
JBrowse link
G Myl7 myosin light chain 7 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYL7 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYL7 mRNA]
CTD PMID:25566086 NCBI chr14:86,144,770...86,147,075
Ensembl chr14:86,143,862...86,147,553
JBrowse link
G Mylk myosin light chain kinase multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MYLK mRNA CTD PMID:25566086 NCBI chr11:69,013,060...69,260,039
Ensembl chr11:69,013,050...69,223,158
JBrowse link
G Mylk3 myosin light chain kinase 3 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYLK3 mRNA CTD PMID:25566086 NCBI chr19:27,388,163...27,442,451
Ensembl chr19:27,404,712...27,441,536
JBrowse link
G Myo5b myosin Vb decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYO5B mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYO5B mRNA]
CTD PMID:25566086 NCBI chr18:70,426,865...70,729,985
Ensembl chr18:70,427,007...70,729,030
JBrowse link
G Myzap myocardial zonula adherens protein decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYZAP mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYZAP mRNA]
CTD PMID:25566086 NCBI chr 8:78,009,019...78,096,409
Ensembl chr 8:77,985,190...78,096,390
JBrowse link
G Nacad NAC alpha domain containing decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NACAD mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NACAD mRNA]
CTD PMID:25566086 NCBI chr14:86,860,607...86,868,605
Ensembl chr14:86,860,608...86,868,598
JBrowse link
G Nanog Nanog homeobox multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [resveratrol results in decreased expression of NANOG protein] CTD PMID:23651583 NCBI chr 4:155,531,906...155,539,268
Ensembl chr 4:155,531,906...155,539,268
JBrowse link
G Napb NSF attachment protein beta increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NAPB mRNA CTD PMID:25566086 NCBI chr 3:143,017,571...143,063,904
Ensembl chr 3:143,020,454...143,063,983
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tretinoin results in increased degradation of NCOA3 protein] CTD PMID:16456540 NCBI chr 3:162,692,176...162,788,582
Ensembl chr 3:162,692,185...162,787,548
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of and results in increased expression of NCOR1 protein CTD PMID:15857753 NCBI chr10:48,629,121...48,772,890
Ensembl chr10:48,629,121...48,772,890
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of and results in increased expression of NCOR2 protein CTD PMID:15857753 NCBI chr12:36,871,917...37,033,701
Ensembl chr12:36,871,999...37,033,701
JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NDFIP1 protein results in decreased expression of SLC6A3 protein] CTD PMID:26300475 NCBI chr18:31,574,759...31,625,286
Ensembl chr18:31,574,821...31,625,274
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NEDD4L mRNA CTD PMID:20061341 NCBI chr18:60,392,376...60,719,720
Ensembl chr18:60,392,376...60,719,720
JBrowse link
G Neurl2 neuralized E3 ubiquitin protein ligase 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NEURL2 mRNA CTD PMID:25566086 NCBI chr 3:161,296,303...161,299,024
Ensembl chr 3:161,296,304...161,299,024
JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Doxorubicin results in increased degradation of NFAT5 protein] CTD PMID:17105721 NCBI chr19:38,446,059...38,533,735
Ensembl chr19:38,446,059...38,533,735
JBrowse link
G Nfe2l1 nuclear factor, erythroid 2-like 1 decreases degradation ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of NFE2L1 protein alternative form CTD PMID:28549828 NCBI chr10:84,686,762...84,699,313
Ensembl chr10:84,682,460...84,698,886
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
decreases expression
increases ubiquitination
decreases degradation
increases expression
increases activity
ISO
EXP
2-tert-butyl-4-quinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of NFE2L2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Homocysteine results in decreased phosphorylation of and results in decreased expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [sulforafan results in increased expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and results in increased stability of and results in increased ubiquitination of NFE2L2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased localization of and results in increased activity of NFE2L2 protein; cyanoginosin LR inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; hydroquinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; quinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NFE2L2 protein modified form
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of NFE2L2 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L2 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [triptolide affects the expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [N-acetylsphingosine results in decreased localization of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [triptolide results in increased ubiquitination of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [sulforafan results in increased activity of NFE2L2 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of NFE2L2 protein
[2-tert-butylhydroquinone co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 2-tert-butylhydroquinone] results in increased expression of NFE2L2 protein; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Cycloheximide] results in increased expression of NFE2L2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Particulate Matter analog results in increased expression of NFE2L2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Vehicle Emissions analog results in increased expression of NFE2L2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [2-tert-butylhydroquinone results in increased ubiquitination of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Cadmium Chloride affects the ubiquitination of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and affects the localization of NFE2L2 protein; exenatide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L2 protein] which results in increased expression of CBR3 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L2 protein
CTD PMID:12441344, PMID:12446695, PMID:14510636, PMID:15319326, PMID:15322212, PMID:18512965, PMID:18550526, PMID:19786557, PMID:20722399, PMID:20806931, PMID:22019695, PMID:22558124, PMID:22606287, PMID:22964297, PMID:25263748, PMID:26598004, PMID:27939242, PMID:28645578, PMID:29618784, PMID:30703377, PMID:30926361, PMID:31319135 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased activity of [NFKB1 protein binds to RELA protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased localization of NFKB1 protein]
CTD PMID:11543732, PMID:14527959, PMID:14581482, PMID:16026644 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases expression
increases phosphorylation
ISO
EXP
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with IL1B protein] results in increased expression of and results in increased phosphorylation of NFKBIA protein; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with TNF protein] results in increased phosphorylation of NFKBIA protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [evodiamine results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [osthol results in decreased phosphorylation of and results in decreased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Deoxycholic Acid results in increased phosphorylation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of and results in increased degradation of NFKBIA protein; MAP1LC3B protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of NFKBIA protein]; sodium arsenite inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with IL1B protein] results in increased expression of and results in increased phosphorylation of NFKBIA protein]; TNF protein affects the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Thiopental] affects the phosphorylation of NFKBIA protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFKBIA protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ammonium Chloride results in increased degradation of NFKBIA protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in decreased expression of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zymosan results in increased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zymosan results in increased phosphorylation of NFKBIA protein]
CTD PMID:11543732, PMID:11698246, PMID:11835394, PMID:11923223, PMID:12185005, PMID:12628480, PMID:12721113, PMID:12883408, PMID:15477007, PMID:16421291, PMID:17644113, PMID:20005289, PMID:22503731, PMID:23423712, PMID:24085292, PMID:25780039 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIB protein] CTD PMID:11543732 NCBI chr 1:86,941,073...86,948,845
Ensembl chr 1:86,941,074...86,948,845
JBrowse link
G Nfkbie NFKB inhibitor epsilon multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in decreased expression of NFKBIE protein] CTD PMID:12185005 NCBI chr 9:17,828,405...17,835,240
Ensembl chr 9:17,828,408...17,835,240
JBrowse link
G Ngf nerve growth factor multiple interactions
increases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NGF mRNA] CTD PMID:25566086 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Ngly1 N-glycanase 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NGLY1 protein binds to UBXN1 protein] CTD PMID:15362974 NCBI chr15:10,405,453...10,455,973
Ensembl chr15:10,405,164...10,455,956
JBrowse link
G Nipsnap2 nipsnap homolog 2 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NIPSNAP2 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NIPSNAP2 mRNA]
CTD PMID:25566086 NCBI chr12:30,527,540...30,566,090
Ensembl chr12:30,527,540...30,566,032
JBrowse link
G Nme3 NME/NM23 nucleoside diphosphate kinase 3 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NME3 mRNA CTD PMID:25566086 NCBI chr10:14,258,232...14,259,365
Ensembl chr10:14,258,380...14,259,336
JBrowse link
G Nmrk2 nicotinamide riboside kinase 2 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NMRK2 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NMRK2 mRNA]
CTD PMID:25566086 NCBI chr 7:11,382,966...11,386,170
Ensembl chr 7:11,383,116...11,386,948
JBrowse link
G Nol3 nucleolar protein 3 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [Doxorubicin results in increased degradation of NOL3 protein] CTD PMID:19139834 NCBI chr19:37,232,567...37,236,668
Ensembl chr19:37,235,001...37,236,649
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [pirinixic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [zinc protoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [zinc protoporphyrin inhibits the reaction [lipoteichoic acid results in increased expression of NOS2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [zinc protoporphyrin inhibits the reaction [Peptidoglycan results in increased expression of NOS2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zymosan results in increased expression of NOS2 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ammonium Chloride results in increased expression of NOS2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NOS2 protein
CTD PMID:11923223, PMID:12628480, PMID:12721113, PMID:17891158, PMID:19376148, PMID:19393675, PMID:20675566, PMID:23395999 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 decreases degradation
increases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of NOS3 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NOS3 protein
CTD PMID:20229525, PMID:20675566 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Notch1 notch receptor 1 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NOTCH1 mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [arsenic trioxide results in decreased expression of NOTCH1 protein]
CTD PMID:24497960, PMID:24801890 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Lead results in increased expression of NQO1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide promotes the reaction [Copper results in decreased expression of NQO1 mRNA]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NQO1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NQO1 mRNA
CTD PMID:16243960, PMID:20061341, PMID:22606287 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
increases ubiquitination
decreases activity
increases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [DNAJC7 protein results in increased expression of NR1I3 protein]; NR1I3 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of DNAJC7 protein]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NR1I3 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased activity of NR1I3 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime affects the localization of NR1I3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein modified form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diethylhexyl Phthalate results in increased activity of NR1I3 protein modified form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [GRIP1 protein binds to NR1I3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Phenobarbital affects the localization of NR1I3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SRC protein binds to NR1I3 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NR1I3 protein
CTD PMID:24224465, PMID:24789201 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dexamethasone results in increased degradation of NR3C1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tubacin results in decreased expression of and results in increased degradation of NR3C1 mRNA]
CTD PMID:20619282, PMID:31778773 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nrg1 neuregulin 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [KU-32 compound inhibits the reaction [NRG1 protein results in increased expression of and results in increased phosphorylation of JUN protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NRG1 protein results in increased expression of and results in increased phosphorylation of JUN protein] CTD PMID:23240583 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Nrip3 nuclear receptor interacting protein 3 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of NRIP3 mRNA CTD PMID:25566086 NCBI chr 1:174,385,424...174,411,141
Ensembl chr 1:174,385,424...174,411,141
JBrowse link
G Nrm nurim multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of NRM mRNA CTD PMID:25566086 NCBI chr20:3,397,834...3,402,264
Ensembl chr20:3,397,834...3,401,315
JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [3-deazaneplanocin results in increased degradation of NSD2 protein] CTD PMID:32001260 NCBI chr14:82,119,210...82,196,501
Ensembl chr14:82,119,210...82,171,480
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NUF2 mRNA CTD PMID:20061341 NCBI chr13:87,818,456...87,847,223
Ensembl chr13:87,818,391...87,847,263
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of OPA1 protein alternative form CTD PMID:20678484 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803
JBrowse link
G Oprd1 opioid receptor, delta 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ARL6IP5 mutant form inhibits the reaction [Morphine results in increased expression of OPRD1 protein]] CTD PMID:21600884 NCBI chr 5:150,288,126...150,323,063
Ensembl chr 5:150,288,126...150,323,063
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of OSGIN1 mRNA CTD PMID:20061341, PMID:25566086 NCBI chr19:52,056,808...52,085,491
Ensembl chr19:52,077,109...52,085,496
JBrowse link
G P2rx6 purinergic receptor P2X 6 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of P2RX6 mRNA CTD PMID:20061341 NCBI chr11:87,434,929...87,445,221
Ensembl chr11:87,435,185...87,445,219
JBrowse link
G Park7 Parkinsonism associated deglycase multiple interactions
decreases response to substance
EXP
ISO
PARK7 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA1A protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Paraquat results in increased sulfation of and results in increased oxidation of PARK7 protein]
PARK7 protein results in decreased susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde
CTD PMID:18331584, PMID:26409479 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of PARP1 protein CTD PMID:15498850, PMID:16051428, PMID:18790767, PMID:20100472 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pax2 paired box 2 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PAX2 mRNA CTD PMID:25566086 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Pbk PDZ binding kinase multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PBK mRNA CTD PMID:25566086 NCBI chr15:42,489,253...42,500,377
Ensembl chr15:42,489,377...42,500,395
JBrowse link
G Pcdh7 protocadherin 7 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PCDH7 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PCDH7 mRNA]
CTD PMID:25566086 NCBI chr14:54,649,054...55,081,632
Ensembl chr14:55,072,200...55,081,551
JBrowse link
G Pdcd6ip programmed cell death 6 interacting protein increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PDCD6IP protein CTD PMID:21692457 NCBI chr 8:121,916,233...121,973,145
Ensembl chr 8:121,916,185...121,973,125
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDGFB mRNA
CTD PMID:15728660, PMID:25566086 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDK1 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDK1 mRNA]
CTD PMID:25566086 NCBI chr 3:58,530,870...58,561,494
Ensembl chr 3:58,530,870...58,558,027
JBrowse link
G Pdlim4 PDZ and LIM domain 4 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PDLIM4 mRNA CTD PMID:25566086 NCBI chr10:39,390,578...39,405,322
Ensembl chr10:39,390,581...39,405,311
JBrowse link
G Pdlim5 PDZ and LIM domain 5 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDLIM5 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDLIM5 mRNA]
CTD PMID:25566086 NCBI chr 2:247,815,214...247,989,198
Ensembl chr 2:247,818,243...247,988,462
JBrowse link
G Pdpn podoplanin multiple interactions
increases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PDPN mRNA] CTD PMID:25566086 NCBI chr 5:161,947,137...161,981,441
Ensembl chr 5:161,947,137...161,981,441
JBrowse link
G Pdxp pyridoxal phosphatase decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDXP mRNA CTD PMID:25566086 NCBI chr 7:120,140,460...120,145,908
Ensembl chr 7:120,140,460...120,145,908
JBrowse link
G Pdyn prodynorphin decreases secretion ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased secretion of PDYN protein alternative form CTD PMID:17670969 NCBI chr 3:122,194,327...122,206,671
Ensembl chr 3:122,194,329...122,206,671
JBrowse link
G Perm1 PPARGC1 and ESRR induced regulator, muscle 1 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PERM1 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PERM1 mRNA]
CTD PMID:25566086 NCBI chr 5:173,640,780...173,646,073
Ensembl chr 5:173,640,780...173,646,073
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PFKFB3 protein CTD PMID:19448625 NCBI chr17:70,632,778...70,713,736
Ensembl chr17:70,684,134...70,713,726
JBrowse link
G Pfkp phosphofructokinase, platelet decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PFKP mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PFKP mRNA]
CTD PMID:25566086 NCBI chr17:68,510,765...68,574,387
Ensembl chr17:68,511,064...68,559,471
JBrowse link
G Pgr progesterone receptor increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PGR protein CTD PMID:15218360 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide results in decreased expression of PIN1 protein] CTD PMID:30093655 NCBI chr 8:21,669,236...21,680,615
Ensembl chr 8:21,669,236...21,680,615
JBrowse link
G Pip5k1b phosphatidylinositol-4-phosphate 5-kinase type 1 beta multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PIP5K1B mRNA] CTD PMID:25566086 NCBI chr 1:242,168,462...242,441,247
Ensembl chr 1:242,168,462...242,441,247
JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [STA 9090 inhibits the reaction [PKD1 gene mutant form results in increased expression of BRD4 protein]] CTD PMID:25877301 NCBI chr10:13,914,057...13,962,008
Ensembl chr10:13,915,214...13,962,008
JBrowse link
G Pkig cAMP-dependent protein kinase inhibitor gamma decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PKIG mRNA CTD PMID:25566086 NCBI chr 3:160,047,257...160,115,180
Ensembl chr 3:160,047,296...160,115,177
JBrowse link
G Plac8 placenta associated 8 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PLAC8 mRNA] CTD PMID:25566086 NCBI chr14:10,692,799...10,714,556
Ensembl chr14:10,692,764...10,714,524
JBrowse link
G Plekha6 pleckstrin homology domain containing A6 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PLEKHA6 mRNA CTD PMID:25566086 NCBI chr13:50,555,454...50,582,236
Ensembl chr13:50,555,454...50,578,720
JBrowse link
G Plekhg2 pleckstrin homology and RhoGEF domain containing G2 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PLEKHG2 mRNA CTD PMID:25566086 NCBI chr 1:85,386,492...85,399,699
Ensembl chr 1:85,386,470...85,399,699
JBrowse link
G Plk1 polo-like kinase 1 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PLK1 mRNA CTD PMID:25566086 NCBI chr 1:192,115,990...192,125,969
Ensembl chr 1:192,115,966...192,125,989
JBrowse link
G Pln phospholamban decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PLN mRNA CTD PMID:25566086 NCBI chr20:34,633,157...34,642,904
Ensembl chr20:34,633,157...34,642,904
JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PLOD3 protein CTD PMID:21692457 NCBI chr12:22,716,421...22,726,982
Ensembl chr12:22,716,423...22,726,982
JBrowse link
G Plvap plasmalemma vesicle associated protein decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PLVAP mRNA CTD PMID:25566086 NCBI chr16:19,906,354...19,918,668
Ensembl chr16:19,906,318...19,918,689
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 decreases degradation
multiple interactions
increases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of PMAIP1 protein
MAPK8 affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PMAIP1 mRNA]; MAPK9 inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PMAIP1 mRNA]
CTD PMID:20802529, PMID:23593480 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Pml PML nuclear body scaffold decreases degradation ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of PML protein modified form CTD PMID:26049103 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226
JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PNPLA3 mRNA CTD PMID:25566086 NCBI chr 7:125,034,760...125,056,165
Ensembl chr 7:125,034,764...125,055,976
JBrowse link
G Pou5f1 POU class 5 homeobox 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of POU5F1 protein CTD PMID:24497960 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases activity
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of PPARG protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [resveratrol results in decreased expression of PPARG protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [rosiglitazone results in decreased expression of PPARG protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of PPARG protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [alitretinoin results in increased activity of PPARG protein]
CTD PMID:15707588, PMID:18555852 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha decreases degradation ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of PPARGC1A protein CTD PMID:20860658 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Ppargc1b PPARG coactivator 1 beta multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PPARGC1B mRNA CTD PMID:25566086 NCBI chr18:56,626,725...56,650,524
Ensembl chr18:56,626,712...56,728,968
JBrowse link
G Ppia peptidylprolyl isomerase A decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PPIA mRNA CTD PMID:15857753 NCBI chr14:86,673,775...86,677,443
Ensembl chr14:86,673,775...86,677,443
JBrowse link
G Ppl periplakin increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PPL mRNA CTD PMID:20061341 NCBI chr10:10,644,572...10,690,223
Ensembl chr10:10,644,572...10,690,223
JBrowse link
G Ppp1r14c protein phosphatase 1, regulatory (inhibitor) subunit 14c decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PPP1R14C mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PPP1R14C mRNA]
CTD PMID:25566086 NCBI chr 1:39,811,314...39,923,071
Ensembl chr 1:39,811,314...39,923,057
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PPP1R15A mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of PPP1R15A protein]
CTD PMID:19135031, PMID:25566086, PMID:29109149 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Ppp1r3g protein phosphatase 1, regulatory subunit 3G multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PPP1R3G mRNA CTD PMID:25566086 NCBI chr17:29,566,032...29,570,294
Ensembl chr17:29,567,404...29,568,447
JBrowse link
G Prc1 protein regulator of cytokinesis 1 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PRC1 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PRC1 mRNA]
CTD PMID:25566086 NCBI chr 1:142,087,181...142,108,746
Ensembl chr 1:142,087,208...142,108,746
JBrowse link
G Prdx1 peroxiredoxin 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PRDX1 mRNA CTD PMID:20061341 NCBI chr 5:135,536,413...135,551,986
Ensembl chr 5:135,536,413...135,551,990
JBrowse link
G Prkcb protein kinase C, beta multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Deoxycholic Acid results in increased expression of PRKCB protein] CTD PMID:17644113 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Prkcd protein kinase C, delta multiple interactions
increases phosphorylation
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NSC606985 results in increased activity of and results in increased cleavage of PRKCD protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [PRKCD protein results in increased ubiquitination of HNRNPK protein]; Glutathione inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of PRKCD protein] CTD PMID:15707588, PMID:19662097, PMID:19747914 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Prkcsh protein kinase C substrate 80K-H increases response to substance ISO PRKCSH gene mutant form results in increased susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde CTD PMID:21685914 NCBI chr 8:23,014,802...23,026,507
Ensembl chr 8:23,014,956...23,026,503
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions
decreases expression
affects expression
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Sorafenib co-treated with PRKN protein] results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [PRKN protein results in decreased expression of SLC11A2 protein alternative form]; Tretinoin affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the expression of PRKN protein alternative form]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PRKN protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PRKN mRNA
CTD PMID:18586549, PMID:20089134, PMID:28673964, PMID:28688199 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Psen1 presenilin 1 multiple interactions ISO [PSEN1 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the reaction [Cycloheximide results in decreased expression of RBPJ protein] CTD PMID:22302987 NCBI chr 6:107,169,514...107,221,000
Ensembl chr 6:107,169,528...107,216,798
JBrowse link
G Psma3 proteasome 20S subunit alpha 3 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMA3 mRNA CTD PMID:15525353 NCBI chr 6:93,423,029...93,444,223
Ensembl chr 6:93,423,002...93,444,240
JBrowse link
G Psma5 proteasome 20S subunit alpha 5 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMA5 mRNA CTD PMID:15525353 NCBI chr 2:211,050,344...211,073,706
Ensembl chr 2:211,050,360...211,073,714
JBrowse link
G Psmb5 proteasome 20S subunit beta 5 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMB5 mRNA CTD PMID:15525353 NCBI chr15:33,259,039...33,263,634
Ensembl chr15:33,259,043...33,263,659
JBrowse link
G Psmb9 proteasome 20S subunit beta 9 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PSMB9 mRNA CTD PMID:20061341 NCBI chr20:3,973,424...3,978,845
Ensembl chr20:3,973,420...3,978,845
JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction and affects the localization of [PSMC5 protein binds to GABBR2 protein] CTD PMID:24482233 NCBI chr10:94,445,877...94,451,811
Ensembl chr10:94,445,877...94,451,811
JBrowse link
G Psmd4 proteasome 26S subunit, non-ATPase 4 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [VCP protein binds to UBXN1 protein binds to PSMD4 protein] CTD PMID:15362974 NCBI chr 2:196,198,303...196,207,569
Ensembl chr 2:196,198,038...196,207,560
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zinc Sulfate results in decreased stability of PTEN protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium Chloride results in increased degradation of and results in decreased expression of PTEN protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium results in increased degradation of and results in decreased expression of PTEN protein]
CTD PMID:20100827, PMID:24449419 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptger1 prostaglandin E receptor 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [[Dinoprostone binds to and results in increased activity of PTGER1 protein] which results in increased expression of HIF1A protein] CTD PMID:20335389 NCBI chr19:24,799,422...24,803,373
Ensembl chr19:24,800,072...24,803,373
JBrowse link
G Ptges3 prostaglandin E synthase 3 decreases degradation
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of PTGES3 protein
4-tosylcyclonovobiocic acid promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of PTGES3 protein]
CTD PMID:19118525 NCBI chr 7:2,479,267...2,497,024
Ensembl chr 7:2,479,311...2,497,013
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zymosan results in increased expression of PTGS2 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [manganese chloride results in increased expression of PTGS2 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased secretion of PTGS2 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PTGS2 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PTGS2 protein
CTD PMID:11230753, PMID:12628480, PMID:12721113, PMID:17084486, PMID:18457675, PMID:22767315, PMID:24085292 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptp4a3 protein tyrosine phosphatase 4A3 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PTP4A3 mRNA CTD PMID:25566086 NCBI chr 7:114,969,699...115,002,902
Ensembl chr 7:114,997,103...115,002,902
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 multiple interactions ISO PTPN1 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of EIF2S1 protein] CTD PMID:28359145 NCBI chr 3:164,665,462...164,711,936
Ensembl chr 3:164,665,532...164,711,848
JBrowse link
G Rab33a RAB33A, member RAS oncogene family decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RAB33A mRNA CTD PMID:25566086 NCBI chr  X:135,348,799...135,360,204
Ensembl chr  X:135,348,436...135,360,203
JBrowse link
G Rad51 RAD51 recombinase multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Mitomycin co-treated with Curcumin] results in decreased expression of RAD51 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased expression of RAD51 protein]] CTD PMID:21810436 NCBI chr 3:110,918,240...110,942,920
Ensembl chr 3:110,918,243...110,942,917
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[arsenic trioxide co-treated with PD 173074] results in decreased expression of RAF1 protein modified form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[arsenic trioxide co-treated with PD 173074] results in decreased expression of RAF1 protein] CTD PMID:27794399 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Ramp1 receptor activity modifying protein 1 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RAMP1 mRNA CTD PMID:25566086 NCBI chr 9:98,313,632...98,364,206
Ensembl chr 9:98,313,632...98,364,205
JBrowse link
G Rara retinoic acid receptor, alpha increases ubiquitination
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of RARA protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tretinoin results in decreased expression of RARA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tretinoin results in increased degradation of RARA protein]
CTD PMID:20945414, PMID:24819975 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Rarres2 retinoic acid receptor responder 2 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RARRES2 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RARRES2 mRNA]
CTD PMID:25566086 NCBI chr 4:78,205,809...78,208,956
Ensembl chr 4:78,205,812...78,208,767
JBrowse link
G Rassf5 Ras association domain family member 5 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [RASSF5 protein results in decreased expression of CTNNB1 protein] CTD PMID:25217643 NCBI chr13:47,956,754...48,022,333
Ensembl chr13:47,956,790...48,022,333
JBrowse link
G Rbl1 RB transcriptional corepressor like 1 increases expression
multiple interactions
increases ubiquitination
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of RBL1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [palbociclib results in decreased expression of RBL1 protein]; palbociclib promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of RBL1 protein]
CTD PMID:20100483 NCBI chr 3:153,263,692...153,321,351
Ensembl chr 3:153,263,692...153,321,352
JBrowse link
G Rbp3 retinol binding protein 3 decreases degradation ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of RBP3 protein mutant form CTD PMID:23486466 NCBI chr16:10,277,775...10,286,243
Ensembl chr16:10,277,775...10,286,243
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of RBPJ protein
[PSEN1 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the reaction [Cycloheximide results in decreased expression of RBPJ protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of RBPJ protein]
CTD PMID:22302987 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450
JBrowse link
G Rcn2 reticulocalbin 2 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of RCN2 protein CTD PMID:21692457 NCBI chr 8:60,709,851...60,726,938
Ensembl chr 8:60,709,851...60,726,936
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases activity
increases ubiquitination
multiple interactions
affects localization
decreases activity
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of RELA protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of RELA protein
Acetylcysteine inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [(+)-JQ1 compound affects the localization of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Cisplatin promotes the reaction [RELA protein binds to TP63 protein alternative form]] which results in increased degradation of TP63 protein alternative form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [BRD4 mutant form affects the localization of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [CIGB-552 peptide results in decreased expression of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Deoxycholic Acid results in increased localization of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein affects the localization of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [trimethyltin chloride affects the localization of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased activity of [NFKB1 protein binds to RELA protein]; SB 203580 inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of RELA protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the localization of RELA protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [halofuginone affects the localization of RELA protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zymosan affects the localization of RELA protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased activity of RELA protein
CTD PMID:11543732, PMID:12628480, PMID:12721113, PMID:14527959, PMID:14581482, PMID:15498850, PMID:16026644, PMID:16489207, PMID:17644113, PMID:18457675, PMID:21088498, PMID:22766066, PMID:23401744, PMID:23423712, PMID:23686307 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RGMA mRNA CTD PMID:25566086 NCBI chr 1:134,699,053...134,742,512
Ensembl chr 1:134,699,299...134,742,514
JBrowse link
G Rhob ras homolog family member B multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SMURF1 protein results in increased degradation of RHOB protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in decreased expression of RHOB protein] CTD PMID:30587574, PMID:31140275 NCBI chr 6:33,689,127...33,691,301
Ensembl chr 6:33,689,127...33,691,301
JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and results in increased ubiquitination of RICTOR protein CTD PMID:25897075 NCBI chr 2:56,013,898...56,105,818
Ensembl chr 2:56,052,643...56,101,803
JBrowse link
G Rnf144b ring finger protein 144B decreases degradation
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of RNF144B protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [2-hydroxy-3-(5-((morpholin-4-yl)methyl)pyridin-2-yl)-1H-indole-5-carbonitrile inhibits the reaction [Estrogens deficiency results in decreased degradation of RNF144B protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [2-hydroxy-3-(5-((morpholin-4-yl)methyl)pyridin-2-yl)-1H-indole-5-carbonitrile results in increased degradation of RNF144B protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride inhibits the reaction [Estrogens deficiency results in decreased degradation of RNF144B protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride results in increased degradation of RNF144B protein]
CTD PMID:29724995 NCBI chr17:17,817,122...17,947,777
Ensembl chr17:17,817,100...17,947,777
JBrowse link
G Rnf187 ring finger protein 187 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ro 31-8220 results in decreased stability of RNF187 protein] CTD PMID:25851810 NCBI chr10:45,273,400...45,279,299
Ensembl chr10:45,273,400...45,279,299
JBrowse link
G Rnf208 ring finger protein 208 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RNF208 mRNA CTD PMID:25566086 NCBI chr 3:2,462,466...2,463,790
Ensembl chr 3:2,462,466...2,463,790
JBrowse link
G Robo4 roundabout guidance receptor 4 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of ROBO4 mRNA CTD PMID:25566086 NCBI chr 8:39,082,693...39,093,344
Ensembl chr 8:39,083,327...39,093,277
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions
decreases phosphorylation
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein]]
Sirolimus promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased phosphorylation of RPS6KB1 protein]
CTD PMID:22689575, PMID:31645432 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of RPTOR protein CTD PMID:25897075 NCBI chr10:108,750,620...109,058,691
Ensembl chr10:108,750,620...109,058,691
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of RRM2 mRNA CTD PMID:25566086 NCBI chr 6:43,884,627...43,890,818
Ensembl chr 6:43,884,678...43,889,515
JBrowse link
G RT1-Bb RT1 class II, locus Bb multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of H2-AB1 mRNA] CTD PMID:25566086 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions
increases expression
ISO [alitretinoin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the localization of RXRA protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [alitretinoin results in increased degradation of RXRA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased degradation of RXRA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of and results in increased expression of RXRA protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of RXRA protein
CTD PMID:12970875, PMID:15707588, PMID:17170071, PMID:22310326 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Sae1 SUMO1 activating enzyme subunit 1 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SAE1 mRNA CTD PMID:20061341 NCBI chr 1:78,277,524...78,333,281
Ensembl chr 1:78,277,515...78,333,321
JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of SCARB1 protein] CTD PMID:22442701 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Selenbp1 selenium binding protein 1 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SELENBP1 mRNA CTD PMID:25566086 NCBI chr 2:196,105,592...196,146,474
Ensembl chr 2:196,105,569...196,113,149
JBrowse link
G Sesn2 sestrin 2 multiple interactions
increases ubiquitination
increases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of SESN2 protein]; Lipopolysaccharides inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of SESN2 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SESN2 protein
CTD PMID:25637945 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117
JBrowse link
G Set SET nuclear proto-oncogene decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SET protein CTD PMID:21692457 NCBI chr19:58,420,635...58,422,153
Ensembl chr19:58,419,961...58,421,504
JBrowse link
G Sf1 splicing factor 1 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of SF1 mRNA CTD PMID:25566086 NCBI chr 1:221,735,512...221,749,216
Ensembl chr 1:221,735,517...221,749,086
JBrowse link
G Sh3kbp1 SH3 domain-containing kinase-binding protein 1 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SH3KBP1 mRNA] CTD PMID:25566086 NCBI chr  X:37,790,004...38,196,365
Ensembl chr  X:37,790,586...38,196,204
JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SIAH2 mRNA CTD PMID:20061341 NCBI chr 2:148,874,151...148,891,900
Ensembl chr 2:148,874,151...148,891,900
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ERCC6 gene mutant form results in decreased expression of SIRT1 protein] CTD PMID:25440059 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Sirt6 sirtuin 6 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SIRT6 protein results in decreased expression of EP300 protein] CTD PMID:27094368 NCBI chr 7:10,937,622...10,943,048
Ensembl chr 7:10,937,599...10,943,063
JBrowse link
G Skp1 S-phase kinase-associated protein 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SKP1 mRNA CTD PMID:20061341 NCBI chr10:37,594,578...37,609,498
Ensembl chr10:37,594,578...37,609,498
JBrowse link
G Skp2 S-phase kinase associated protein 2 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SKP2 mRNA CTD PMID:20061341 NCBI chr 2:58,506,146...58,534,211
Ensembl chr 2:58,506,151...58,534,211
JBrowse link
G Slbp stem-loop binding protein multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in decreased expression of SLBP protein] CTD PMID:25266719 NCBI chr14:82,356,916...82,366,368
Ensembl chr14:82,356,916...82,366,368
JBrowse link
G Slc10a2 solute carrier family 10 member 2 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC10A2 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [resveratrol results in decreased expression of SLC10A2 protein]
CTD PMID:23872411, PMID:24498857 NCBI chr16:90,324,420...90,350,254
Ensembl chr16:90,324,361...90,345,865
JBrowse link
G Slc11a2 solute carrier family 11 member 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [PRKN protein results in decreased expression of SLC11A2 protein alternative form] CTD PMID:20089134 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212
JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression
multiple interactions
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC2A1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [methylmercuric chloride results in decreased expression of SLC2A1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Methylmercury Compounds results in decreased expression of SLC2A1 protein]
CTD PMID:17442736, PMID:31850806, PMID:32461003 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc31a1 solute carrier family 31 member 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cisplatin results in increased degradation of SLC31A1 protein] CTD PMID:17108132 NCBI chr 5:78,222,504...78,249,358
Ensembl chr 5:78,222,504...78,249,358
JBrowse link
G Slc39a4 solute carrier family 39 member 4 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zinc results in increased degradation of SLC39A4 protein] CTD PMID:17202136 NCBI chr 7:117,675,718...117,682,586
Ensembl chr 7:117,675,720...117,680,004
JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NDFIP1 protein results in decreased expression of SLC6A3 protein] CTD PMID:26300475 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
G Slc6a9 solute carrier family 6 member 9 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC6A9 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC6A9 mRNA]
CTD PMID:25566086 NCBI chr 5:136,669,674...136,703,702
Ensembl chr 5:136,669,674...136,703,697
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC7A11 mRNA CTD PMID:25566086 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Slc7a3 solute carrier family 7 member 3 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC7A3 mRNA CTD PMID:25566086 NCBI chr  X:70,972,767...70,979,466
Ensembl chr  X:70,972,765...70,978,952
JBrowse link
G Sln sarcolipin decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SLN mRNA CTD PMID:25566086 NCBI chr 8:58,431,407...58,435,654
Ensembl chr 8:58,431,407...58,435,654
JBrowse link
G Smtnl2 smoothelin-like 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SMTNL2 mRNA CTD PMID:25566086 NCBI chr10:58,951,845...58,973,020
Ensembl chr10:58,951,842...58,973,020
JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SMURF1 protein results in increased degradation of RHOB protein] CTD PMID:30587574 NCBI chr12:11,433,815...11,526,465
Ensembl chr12:11,407,213...11,526,465
JBrowse link
G Snrk SNF related kinase decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SNRK mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SNRK mRNA]
CTD PMID:25566086 NCBI chr 8:130,749,806...130,805,225
Ensembl chr 8:130,749,838...130,803,597
JBrowse link
G Soat2 sterol O-acyltransferase 2 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SOAT2 mRNA CTD PMID:25566086 NCBI chr 7:143,754,892...143,767,989
Ensembl chr 7:143,754,892...143,767,989
JBrowse link
G Socs3 suppressor of cytokine signaling 3 decreases degradation ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of SOCS3 protein CTD PMID:23782265 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
increases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[SOD1 protein results in increased susceptibility to Thimerosal] which results in decreased expression of KCNIP3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Glucose deficiency results in increased degradation of SOD1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SOD1 mRNA
CTD PMID:17309078, PMID:20061341, PMID:30503815 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO [SOD2 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of HDAC2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of SOD2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; CAT protein inhibits the reaction [[SOD2 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of HDAC2 protein] CTD PMID:12161520, PMID:24973648 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sort1 sortilin 1 multiple interactions
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tetrabromocinnamic acid results in increased degradation of SORT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [wortmannin results in increased degradation of SORT1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SORT1 protein
CTD PMID:25805502 NCBI chr 2:211,078,092...211,156,312
Ensembl chr 2:211,078,334...211,156,312
JBrowse link
G Sox18 SRY-box transcription factor 18 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SOX18 mRNA CTD PMID:25566086 NCBI chr 3:177,177,237...177,179,039
Ensembl chr 3:177,177,310...177,179,127
JBrowse link
G Sox9 SRY-box transcription factor 9 multiple interactions ISO [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of SRY protein mutant form] which results in increased expression of SOX9 mRNA CTD PMID:27576690 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [SP1 protein binds to ARNT promoter]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of and results in increased activity of SP1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [5-(4-((6-(allyloxy)-2,5,7,8-tetramethylchroman-2-yl)methoxy)-3-methoxybenzylidene)thiazolidine-2,4-dione results in decreased expression of SP1 protein]
CTD PMID:14529614, PMID:17409431 NCBI chr 7:144,014,173...144,044,635
Ensembl chr 7:144,014,173...144,044,629
JBrowse link
G Sp3 Sp3 transcription factor multiple interactions
increases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of SP3 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SP3 protein
CTD PMID:25068794 NCBI chr 3:59,644,579...59,689,011
Ensembl chr 3:59,646,015...59,688,692
JBrowse link
G Spon2 spondin 2 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SPON2 mRNA] CTD PMID:25566086 NCBI chr14:82,815,158...82,824,529
Ensembl chr14:82,818,663...82,824,599
JBrowse link
G Spsb4 splA/ryanodine receptor domain and SOCS box containing 4 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SPSB4 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SPSB4 mRNA]
CTD PMID:25566086 NCBI chr 8:104,840,939...104,912,959
Ensembl chr 8:104,840,940...104,912,959
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [ATG13 protein results in decreased expression of SQSTM1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [ATG7 protein results in decreased expression of SQSTM1 protein] CTD PMID:27629431 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[arsenic trioxide co-treated with PD 173074] results in decreased expression of SRC protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SRC protein binds to NR1I3 protein] CTD PMID:24224465, PMID:27794399 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Srl sarcalumenin decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SRL mRNA CTD PMID:25566086 NCBI chr10:11,240,135...11,284,325
Ensembl chr10:11,240,138...11,284,332
JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [KAT5 protein results in increased acetylation of and results in increased degradation of SRSF2 protein] CTD PMID:21157427 NCBI chr10:105,792,779...105,795,986
Ensembl chr10:105,792,779...105,795,958
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SRXN1 mRNA CTD PMID:25566086 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Sry sex determining region Y decreases degradation
increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of SRY protein mutant form
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SRY protein modified form
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of SRY protein mutant form] which results in increased expression of SOX9 mRNA; SRY protein mutant form promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SRY protein modified form]
CTD PMID:27576690 NCBI chr  Y:327,176...327,685
Ensembl chr  Y:327,166...329,299
JBrowse link
G Sspn sarcospan decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SSPN mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SSPN mRNA]
CTD PMID:25566086 NCBI chr 4:180,291,389...180,325,799
Ensembl chr 4:180,291,389...180,324,408
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tretinoin results in increased expression of and results in increased phosphorylation of STAT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tretinoin results in increased expression of STAT1 mRNA] CTD PMID:20945414 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stat6 signal transducer and activator of transcription 6 affects phosphorylation ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the phosphorylation of STAT6 protein CTD PMID:12459556 NCBI chr 7:70,946,228...70,963,542
Ensembl chr 7:70,946,228...70,964,484
JBrowse link
G Stk11 serine/threonine kinase 11 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [5-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one inhibits the reaction [STK11 mutant form results in increased expression of MYC protein]] CTD PMID:24793789 NCBI chr 7:12,440,751...12,457,513
Ensembl chr 7:12,440,751...12,457,513
JBrowse link
G Strip2 striatin interacting protein 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of STRIP2 mRNA CTD PMID:25566086 NCBI chr 4:57,204,850...57,248,912
Ensembl chr 4:57,204,944...57,246,675
JBrowse link
G Sts steroid sulfatase multiple interactions
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IGF2 protein results in increased expression of STS mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IGF2 protein results in increased expression of STS protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tretinoin results in increased activity of STS protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of STS mRNA
CTD PMID:16178010, PMID:24055520 NCBI chr  X:45,420,418...45,428,748
Ensembl chr  X:45,420,596...45,428,750
JBrowse link
G Suv39h1 suppressor of variegation 3-9 homolog 1 multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; [TNF protein co-treated with 6-formylindolo(3,2-b)carbazole co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; [TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; [TNF protein co-treated with Sirolimus co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; AHR protein affects the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein] CTD PMID:31676321 NCBI chr  X:146,532,002...146,533,538 JBrowse link
G Swt1 SWT1 RNA endoribonuclease homolog multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of SWT1 mRNA CTD PMID:25566086 NCBI chr13:68,728,266...68,785,800
Ensembl chr13:68,728,266...68,785,771
JBrowse link
G Sybu syntabulin multiple interactions
increases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SYBU mRNA] CTD PMID:25566086 NCBI chr 7:83,600,614...83,670,121
Ensembl chr 7:83,600,617...83,670,356
JBrowse link
G Synpo synaptopodin multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of SYNPO mRNA CTD PMID:25566086 NCBI chr18:55,863,081...55,921,412
Ensembl chr18:55,865,467...55,916,220
JBrowse link
G Syp synaptophysin multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [AGT protein results in increased degradation of SYP protein] CTD PMID:18487452 NCBI chr  X:15,694,699...15,709,244
Ensembl chr  X:15,695,566...15,707,436
JBrowse link
G Taf1 TATA-box binding protein associated factor 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [5-(4-((6-(allyloxy)-2,5,7,8-tetramethylchroman-2-yl)methoxy)-3-methoxybenzylidene)thiazolidine-2,4-dione results in decreased expression of TAF1 protein] CTD PMID:17409431 NCBI chr  X:71,412,291...71,486,456
Ensembl chr  X:71,412,289...71,485,085
JBrowse link
G Taf1a TATA-box binding protein associated factor, RNA polymerase I subunit A increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TAF1A mRNA CTD PMID:25566086 NCBI chr13:101,770,278...101,807,975
Ensembl chr13:101,790,865...101,806,900
JBrowse link
G Tardbp TAR DNA binding protein affects localization ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the localization of TARDBP protein CTD PMID:19765185 NCBI chr 5:165,432,089...165,442,232
Ensembl chr 5:165,432,095...165,442,048
JBrowse link
G Tdrp testis development related protein increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TDRP mRNA CTD PMID:25566086 NCBI chr16:80,729,342...80,755,397
Ensembl chr16:80,729,400...80,755,415
JBrowse link
G Tenm4 teneurin transmembrane protein 4 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TENM4 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TENM4 mRNA]
CTD PMID:25566086 NCBI chr 1:161,183,858...161,885,094
Ensembl chr 1:161,401,527...161,880,923
JBrowse link
G Tert telomerase reverse transcriptase multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [APP protein modified form results in decreased expression of and results in decreased activity of TERT protein] CTD PMID:21520056 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tesc tescalcin decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TESC mRNA CTD PMID:25566086 NCBI chr12:44,141,258...44,174,701
Ensembl chr12:44,141,422...44,174,583
JBrowse link
G Tfam transcription factor A, mitochondrial multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [troglitazone results in decreased expression of TFAM mRNA] CTD PMID:20860658 NCBI chr20:18,594,057...18,606,106
Ensembl chr20:18,594,037...18,606,151
JBrowse link
G Tfrc transferrin receptor decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TFRC mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TFRC mRNA]
CTD PMID:25566086 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TGFB1 protein results in decreased expression of LPIN1 protein] CTD PMID:27345520 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfbi transforming growth factor, beta induced decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TGFBI mRNA CTD PMID:25566086 NCBI chr17:8,400,123...8,429,338
Ensembl chr17:8,400,146...8,429,338
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tolfenamic acid results in decreased expression of TGFBR1 protein] CTD PMID:31381904 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Thy1 Thy-1 cell surface antigen decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of THY1 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of THY1 mRNA]
CTD PMID:25566086 NCBI chr 8:48,382,121...48,387,271
Ensembl chr 8:48,382,121...48,386,935
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of TIPARP mRNA] CTD PMID:12147270 NCBI chr 2:157,316,293...157,342,979
Ensembl chr 2:157,316,266...157,341,469
JBrowse link
G Tk1 thymidine kinase 1 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TK1 mRNA
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TK1 mRNA
CTD PMID:20061341, PMID:25566086 NCBI chr10:106,817,556...106,828,888
Ensembl chr10:106,817,601...106,828,884
JBrowse link
G Tmem176a transmembrane protein 176A multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TMEM176A mRNA CTD PMID:25566086 NCBI chr 4:78,458,735...78,462,415
Ensembl chr 4:78,458,625...78,462,423
JBrowse link
G Tmem176b transmembrane protein 176B multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TMEM176B mRNA CTD PMID:25566086 NCBI chr 4:78,450,724...78,458,600
Ensembl chr 4:78,450,724...78,458,179
JBrowse link
G Tmem204 transmembrane protein 204 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TMEM204 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TMEM204 mRNA]
CTD PMID:25566086 NCBI chr10:14,417,608...14,446,272
Ensembl chr10:14,417,609...14,443,010
JBrowse link
G Tmod1 tropomodulin 1 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TMOD1 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TMOD1 mRNA]
CTD PMID:25566086 NCBI chr 5:61,635,244...61,712,052
Ensembl chr 5:61,657,507...61,712,051
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with TNF protein] results in increased phosphorylation of NFKBIA protein; [TNF protein co-treated with 6-formylindolo(3,2-b)carbazole co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; [TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; [TNF protein co-treated with Sirolimus co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; AHR protein affects the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased activity of MMP9 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CX3CL1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of VEGFA mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased secretion of CCL2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased secretion of PTGS2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased secretion of VEGFA protein]; TNF protein affects the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Thiopental] affects the phosphorylation of NFKBIA protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zymosan results in increased expression of TNF mRNA]
CTD PMID:11230753, PMID:11698246, PMID:12185005, PMID:12628480, PMID:12883408, PMID:14572618, PMID:19393675, PMID:23395999, PMID:24085292, PMID:24613819, PMID:28134560, PMID:31676321 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip8l1 TNF alpha induced protein 8 like 1 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TNFAIP8L1 mRNA CTD PMID:20061341 NCBI chr 9:10,894,949...10,905,647
Ensembl chr 9:10,896,680...10,897,240
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TNFRSF10A protein CTD PMID:16287099 NCBI chr15:51,433,853...51,464,215 JBrowse link
G Tnni1 troponin I1, slow skeletal type decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TNNI1 mRNA CTD PMID:25566086 NCBI chr13:52,624,856...52,637,297
Ensembl chr13:52,624,878...52,637,297
JBrowse link
G Tnni2 troponin I2, fast skeletal type decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TNNI2 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TNNI2 mRNA]
CTD PMID:25566086 NCBI chr 1:215,609,110...215,611,652
Ensembl chr 1:215,609,036...215,611,658
JBrowse link
G Tnni3 troponin I3, cardiac type multiple interactions
decreases expression
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Doxorubicin results in decreased expression of TNNI3 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TNNI3 mRNA
CTD PMID:19801490, PMID:25566086 NCBI chr 1:72,882,806...72,886,490
Ensembl chr 1:72,882,806...72,886,488
JBrowse link
G Top2a DNA topoisomerase II alpha multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]] CTD PMID:17575151 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
increases ubiquitination
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Capsaicin results in increased degradation of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Chlorpyrifos results in decreased expression of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in increased degradation of TP53 protein mutant form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of TP53 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TP53 protein modified form
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of TP53 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in decreased degradation of TP53 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Acetaminophen results in increased degradation of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of and results in increased expression of TP53 protein
CTD PMID:10837373, PMID:16330492, PMID:18463101, PMID:18951928, PMID:19699254, PMID:20530418, PMID:21454520, PMID:26612707, PMID:27129209, PMID:27993609 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp63 tumor protein p63 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Cisplatin promotes the reaction [RELA protein binds to TP63 protein alternative form]] which results in increased degradation of TP63 protein alternative form] CTD PMID:21088498 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501
JBrowse link
G Trib2 tribbles pseudokinase 2 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TRIB2 mRNA CTD PMID:25566086 NCBI chr 6:41,016,722...41,040,972
Ensembl chr 6:41,016,730...41,039,437
JBrowse link
G Tril TLR4 interactor with leucine-rich repeats decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TRIL mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TRIL mRNA]
CTD PMID:25566086 NCBI chr 4:83,967,695...83,972,540
Ensembl chr 4:83,967,696...83,972,540
JBrowse link
G Trim72 tripartite motif containing 72 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TRIM72 mRNA CTD PMID:25566086 NCBI chr 1:199,450,042...199,457,902
Ensembl chr 1:199,449,973...199,457,895
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]] CTD PMID:20671745 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
G Tsc22d4 TSC22 domain family, member 4 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TSC22D4 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TSC22D4 mRNA]
CTD PMID:25566086 NCBI chr12:22,008,956...22,021,814
Ensembl chr12:22,009,011...22,021,851
JBrowse link
G Txnl1 thioredoxin-like 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [arsenite results in increased degradation of TXNL1 protein] CTD PMID:19349280 NCBI chr18:59,056,454...59,086,278
Ensembl chr18:59,059,375...59,086,256
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TXNRD1 mRNA CTD PMID:18550526 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Tymp thymidine phosphorylase multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Fluorouracil co-treated with Cisplatin] results in decreased stability of TYMP protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tanespimycin inhibits the reaction [salinomycin results in increased expression of TYMP protein]] CTD PMID:21444628, PMID:30796972 NCBI chr 7:130,342,481...130,347,845
Ensembl chr 7:130,342,483...130,347,587
JBrowse link
G Tyms thymidylate synthetase multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Fluorouracil co-treated with Cisplatin] results in decreased stability of TYMS protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [trichostatin A results in decreased expression of TYMS protein] CTD PMID:17172411, PMID:21444628 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
JBrowse link
G Tyr tyrosinase multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Fenofibrate results in decreased expression of TYR protein] CTD PMID:23872139 NCBI chr 1:151,012,598...151,106,802
Ensembl chr 1:151,012,598...151,106,802
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of UBE2C mRNA CTD PMID:20061341 NCBI chr 3:161,236,971...161,239,371
Ensembl chr 3:161,236,898...161,241,159
JBrowse link
G Ube2t ubiquitin-conjugating enzyme E2T decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of UBE2T mRNA CTD PMID:20061341 NCBI chr13:51,790,877...51,801,379
Ensembl chr13:51,795,867...51,801,163
JBrowse link
G Ubqln1 ubiquilin 1 increases stability ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of UBQLN1 protein mutant form CTD PMID:24747970 NCBI chr17:6,840,441...6,878,842
Ensembl chr17:6,840,463...6,878,844
JBrowse link
G Ubr1 ubiquitin protein ligase E3 component n-recognin 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of UBR1 mRNA CTD PMID:20061341 NCBI chr 3:112,800,557...112,910,038
Ensembl chr 3:112,800,557...112,876,773
JBrowse link
G Ubxn1 UBX domain protein 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NGLY1 protein binds to UBXN1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [VCP protein binds to UBXN1 protein binds to PSMD4 protein] CTD PMID:15362974 NCBI chr 1:225,067,953...225,071,944
Ensembl chr 1:225,068,009...225,071,945
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of UCHL1 mRNA CTD PMID:20061341 NCBI chr14:43,133,224...43,143,942
Ensembl chr14:43,133,218...43,143,973
JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of UFD1 mRNA
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of UFD1 mRNA
CTD PMID:20061341, PMID:25566086 NCBI chr11:86,304,836...86,328,478
Ensembl chr11:86,304,815...86,328,469
JBrowse link
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of UHRF1 mRNA CTD PMID:25566086 NCBI chr 9:10,738,211...10,758,403
Ensembl chr 9:10,738,222...10,757,954
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein] CTD PMID:27629431 NCBI chr12:51,908,105...51,934,704
Ensembl chr12:51,908,448...51,934,702
JBrowse link
G Unc13c unc-13 homolog C multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of UNC13C mRNA] CTD PMID:25566086 NCBI chr 8:80,202,736...80,656,363
Ensembl chr 8:80,203,609...80,631,926
JBrowse link
G Usp14 ubiquitin specific peptidase 14 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of USP14 mRNA CTD PMID:20061341 NCBI chr18:1,178,785...1,216,573
Ensembl chr18:1,178,787...1,216,409
JBrowse link
G Usp28 ubiquitin specific peptidase 28 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [nickel sulfate results in decreased expression of USP28 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen deficiency results in decreased expression of USP28 protein] CTD PMID:20046830 NCBI chr 8:53,295,188...53,355,572
Ensembl chr 8:53,295,222...53,355,572
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions
increases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of VCAM1 mRNA
CTD PMID:11698246, PMID:18457675 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vcp valosin-containing protein increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of VCP protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [VCP protein binds to UBXN1 protein binds to PSMD4 protein]
CTD PMID:15362974 NCBI chr 5:58,426,548...58,445,953
Ensembl chr 5:58,426,549...58,445,953
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases expression
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [methylmercuric chloride results in decreased expression of VEGFA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Methylmercury Compounds results in decreased expression of VEGFA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of VEGFA mRNA]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of VEGFA protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [andrographolide results in decreased expression of VEGFA mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [andrographolide results in decreased expression of VEGFA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of VEGFA mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased secretion of VEGFA protein]
CTD PMID:12590138, PMID:24613819, PMID:28651835, PMID:31850806, PMID:32461003 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor multiple interactions ISO [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HIF1A protein binds to VHL protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [VHL protein binds to HIF1A protein]; manganese chloride inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HIF1A protein binds to VHL protein]] CTD PMID:17973296, PMID:19263519 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845
JBrowse link
G Vim vimentin multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [AHR protein results in decreased expression of VIM protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [AHR protein binds to VIM protein] CTD PMID:27752740 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Vwf von Willebrand factor decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of VWF mRNA CTD PMID:25566086 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
JBrowse link
G Xbp1 X-box binding protein 1 decreases response to substance
multiple interactions
ISO XBP1 protein results in decreased susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde
[XBP1 mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] inhibits the reaction [Tobacco Smoke Pollution analog results in increased phosphorylation of EIF2S1 protein]; [XBP1 mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] promotes the reaction [Tobacco Smoke Pollution analog results in increased cleavage of CASP3 protein]
CTD PMID:19135031, PMID:25568320 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Xiap X-linked inhibitor of apoptosis multiple interactions
increases cleavage
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[pifithrin co-treated with Topotecan] results in increased degradation of XIAP protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in decreased expression of XIAP protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in decreased expression of XIAP protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [trimethyltin chloride results in decreased expression of XIAP protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of XIAP protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Topotecan results in increased degradation of XIAP protein]
CTD PMID:16287099, PMID:19812371, PMID:21411500, PMID:22627131, PMID:23423712 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000
JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in decreased expression of XPC protein] CTD PMID:28237621 NCBI chr 4:123,134,457...123,161,985
Ensembl chr 4:123,134,457...123,161,985
JBrowse link
G Zbtb8b zinc finger and BTB domain containing 8b multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ZBTB8B mRNA] CTD PMID:25566086 NCBI chr 5:147,628,566...147,644,209
Ensembl chr 5:147,628,899...147,635,789
JBrowse link
G Zfand2a zinc finger AN1-type containing 2A increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ZFAND2A mRNA CTD PMID:25566086 NCBI chr12:17,252,093...17,263,477
Ensembl chr12:17,252,093...17,263,477
JBrowse link
G Zfyve21 zinc finger FYVE-type containing 21 multiple interactions ISO