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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:alpha-terpineol
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Accession:CHEBI:22469 term browser browse the term
Definition:A terpineol that is propan-2-ol substituted by a 4-methylcyclohex-3-en-1-yl group at position 2.
Synonyms:related_synonym: (+)-p-menth-1-en-8-ol;   1-alpha-terpineol;   1-menthene-8-ol;   1-methyl-4-isopropyl-1-cyclohexen-8-ol;   1-methyl-4-isopropyl-1-cyclohexene-8-ol;   2-(4-Methylcyclohex-3-en-1-yl)propan-2-ol;   2-(4-methyl-3-cyclohexenyl)-2-propanol;   Formula=C10H18O;   InChI=1S/C10H18O/c1-8-4-6-9(7-5-8)10(2,3)11/h4,9,11H,5-7H2,1-3H3;   InChIKey=WUOACPNHFRMFPN-UHFFFAOYSA-N;   SMILES=CC1=CCC(CC1)C(C)(C)O;   alpha,alpha,4-trimethyl-3-cyclohexene-1-methanol
 xref: BPDB:2015;   Beilstein:1906604;   CAS:98-55-5;   Gmelin:406992;   HMDB:HMDB0004043;   KEGG:C16772;   KNApSAcK:C00029674
 xref_mesh: MESH:C016775
 xref: PMID:16356517;   Reaxys:1906604;   UM-BBD_compID:c0669



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alpha-terpineol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsd cathepsin D increases expression ISO alpha-terpineol results in increased expression of CTSD mRNA CTD PMID:31393563 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 multiple interactions ISO alpha-terpineol inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA] CTD PMID:31393563 NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases activity
ISO alpha-terpineol binds to and results in increased activity of ESR1 protein; NCOA2 protein promotes the reaction [alpha-terpineol results in increased activity of ESR1 protein] CTD PMID:27633901 PMID:31393563 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [alpha-terpineol results in increased expression of GREB1 mRNA] CTD PMID:31393563 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO NCOA2 protein promotes the reaction [alpha-terpineol results in increased activity of ESR1 protein] CTD PMID:31393563 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
JBrowse link
G RGD1559459 similar to Expressed sequence AI788959 multiple interactions ISO alpha-terpineol inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA] CTD PMID:31393563 NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704
JBrowse link
G Sec14l2 SEC14-like lipid binding 2 multiple interactions ISO alpha-terpineol inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA] CTD PMID:31393563 NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788
JBrowse link
G Ugt2b15 UDP glucuronosyltransferase family 2 member B15 increases metabolic processing EXP UGT2B15 protein results in increased metabolism of alpha-terpineol CTD PMID:7574722 NCBI chr14:20,768,015...20,783,599
Ensembl chr14:20,768,015...20,783,589
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20056
    role 20008
      biological role 20007
        biochemical role 19640
          metabolite 19623
            eukaryotic metabolite 19326
              plant metabolite 17657
                alpha-terpineol 8
                  (R)-(+)-alpha-terpineol 0
                  (S)-(-)-alpha-terpineol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20056
    subatomic particle 20054
      composite particle 20054
        hadron 20054
          baryon 20054
            nucleon 20054
              atomic nucleus 20054
                atom 20054
                  main group element atom 19956
                    main group molecular entity 19956
                      s-block molecular entity 19752
                        hydrogen molecular entity 19745
                          hydrides 19114
                            organic hydride 18653
                              organic fundamental parent 18653
                                hydrocarbon 18389
                                  terpene 13624
                                    terpenoid 13273
                                      monoterpenoid 1233
                                        p-menthane monoterpenoid 441
                                          terpineol 10
                                            alpha-terpineol 8
                                              (R)-(+)-alpha-terpineol 0
                                              (S)-(-)-alpha-terpineol 0
paths to the root