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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:alpha-N-substituted L-arginine
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Accession:CHEBI:22440 term browser browse the term
Definition:An L-arginine derivative that is L-arginine in which one of the hydrogens attached to the alpha-nitrogen has replaced by another atom or group.
Synonyms:related_synonym: Formula=C6H13N4O2R;   SMILES=NC(=N)NCCC[C@H](N[*])C(O)=O;   alpha-N-substituted L-arginines
 alt_id: CHEBI:10318
 xref: KEGG:C04026


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argatroban term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO argatroban inhibits the reaction [Dietary Fats results in increased expression of ACTA2 protein] CTD PMID:22841818 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503 		JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 multiple interactions ISO argatroban inhibits the reaction [Dietary Fats results in increased expression of ADGRE1 mRNA] CTD PMID:22841818 NCBI chr 9:2,329,398...2,484,959
Ensembl chr 9:2,329,438...2,484,959 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO argatroban inhibits the reaction [Dietary Fats results in increased expression of CCL2 mRNA]; argatroban inhibits the reaction [Dietary Fats results in increased expression of CCL2 protein] CTD PMID:22841818 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Cd68 Cd68 molecule multiple interactions ISO argatroban inhibits the reaction [Dietary Fats results in increased expression of CD68 mRNA] CTD PMID:22841818 NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,880,563...54,882,540 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO argatroban inhibits the reaction [Dietary Fats results in increased expression of COL1A1 mRNA] CTD PMID:22841818 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO argatroban affects the reaction [Dietary Fats results in increased expression of CXCL2 mRNA] CTD PMID:22841818 NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255 		JBrowse link
G F2 coagulation factor II, thrombin multiple interactions ISO argatroban inhibits the reaction [Dietary Fats results in increased expression of F2 protein]
argatroban binds to and results in decreased activity of F2 protein 		CTD PMID:15080313 PMID:16084352 PMID:18449412 PMID:22841818 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO argatroban inhibits the reaction [Dietary Fats results in increased expression of ICAM1 mRNA] CTD PMID:22841818 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO argatroban inhibits the reaction [[LDLR gene mutant form results in increased susceptibility to Dietary Fats] which results in increased abundance of Cholesterol]; argatroban inhibits the reaction [[LDLR gene mutant form results in increased susceptibility to Dietary Fats] which results in increased abundance of Triglycerides] CTD PMID:22841818 NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO argatroban inhibits the reaction [Dietary Fats results in increased expression of TIMP1 mRNA] CTD PMID:22841818 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20871
    role 20829
      application 20632
        indicator 8820
          biomarker 6604
            L-arginine 125
              L-arginine derivative 101
                alpha-N-substituted L-arginine 10
                  N(2)-(2-carboxyethyl)-L-arginine 0
                  argatroban 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 20871
    subatomic particle 20869
      composite particle 20869
        hadron 20869
          baryon 20869
            nucleon 20869
              atomic nucleus 20869
                atom 20869
                  main group element atom 20792
                    main group molecular entity 20792
                      s-block molecular entity 20587
                        hydrogen molecular entity 20571
                          hydrides 19700
                            inorganic hydride 18600
                              pnictogen hydride 18587
                                nitrogen hydride 18501
                                  azane 18262
                                    ammonia 18261
                                      organic amino compound 18261
                                        amino acid 16337
                                          alpha-amino acid 14249
                                            L-alpha-amino acid 12385
                                              glutamine family amino acid 10348
                                                L-arginine 125
                                                  L-arginine derivative 101
                                                    alpha-N-substituted L-arginine 10
                                                      N(2)-(2-carboxyethyl)-L-arginine 0
                                                      argatroban 10
paths to the root