alkaloid - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	alkaloid	go back to main search page
Accession:	CHEBI:22315	browse the term
Definition:	Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids.
Synonyms:	exact_synonym:	alkaloids
	related_synonym:	Alkaloide; alcaloide; alcaloides
	alt_id:	MESH:D000470
	xref_mesh:	MESH:D000470
	xref:	Wikipedia:Alkaloid

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Genes (74)

(S)-colchicine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-1-microglobulin/bikunin precursor

decreases uptake

Colchicine results in decreased uptake of AMBP protein

NCBI chr 1:254,683,885...254,703,220
Ensembl chr 1:254,683,891...254,703,225

(S)-nicotine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adenylate cyclase activating polypeptide 1

multiple interactions

Nicotine inhibits the reaction [[Carbon Dioxide co-treated with Oxygen deficiency] results in decreased expression of ADCYAP1 protein]

NCBI chr 6:105,414,628...105,422,294
Ensembl chr 6:105,414,631...105,422,294

G

ADCYAP receptor type I

decreases expression

Nicotine results in decreased expression of ADCYAP1R1 protein

NCBI chr18:41,915,180...41,972,327
Ensembl chr18:41,917,428...41,972,301

G

anti-Mullerian hormone

decreases expression
decreases secretion

Nicotine results in decreased expression of AMH mRNA
Nicotine results in decreased secretion of AMH protein

NCBI chr 2:76,415,564...76,418,315
Ensembl chr 2:76,414,427...76,418,312

G

BCL2 apoptosis regulator

decreases expression

Nicotine results in decreased expression of BCL2 mRNA

NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879

G

cholinergic receptor nicotinic alpha 2 subunit

multiple interactions

Nicotine affects the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNA2 protein]

NCBI chr14:11,193,732...11,204,334
Ensembl chr14:11,195,228...11,207,650

G

cholinergic receptor nicotinic alpha 3 subunit

multiple interactions

Nicotine affects the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNA3 protein]

NCBI chr 7:47,361,710...47,382,743
Ensembl chr 7:47,361,899...47,384,303

G

cholinergic receptor nicotinic alpha 7 subunit

multiple interactions

Nicotine affects the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNA7 protein]

NCBI chr 1:142,803,697...142,937,124
Ensembl chr 1:142,803,701...142,937,123

G

cholinergic receptor nicotinic alpha 9 subunit

multiple interactions

Nicotine affects the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNA9 protein]

NCBI chr 8:31,430,933...31,456,385
Ensembl chr 8:31,443,043...31,456,384

G

cholinergic receptor nicotinic beta 2 subunit

multiple interactions

Nicotine affects the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNB2 protein]

NCBI chr 4:95,196,992...95,211,084
Ensembl chr 4:95,198,717...95,211,037

G

cytochrome P450 19A3

decreases expression

Nicotine results in decreased expression of CYP19A1 mRNA

NCBI chr 1:120,476,890...120,556,103
Ensembl chr 1:120,367,667...120,695,899

G

follicle stimulating hormone receptor

decreases expression

Nicotine results in decreased expression of FSHR mRNA

NCBI chr 3:91,607,236...91,775,255
Ensembl chr 3:91,607,305...91,774,683

G

inhibin subunit beta B

decreases expression
decreases secretion

Nicotine results in decreased expression of INHBB mRNA
Nicotine results in decreased secretion of INHBB protein

NCBI chr15:30,999,994...31,004,405
Ensembl chr15:30,999,520...31,004,405

G

integrin subunit beta 1

decreases expression

Nicotine results in decreased expression of ITGB1 mRNA

NCBI chr10:56,078,393...56,130,608
Ensembl chr10:56,078,396...56,173,326

G

laminin subunit beta 1

decreases expression

Nicotine results in decreased expression of LAMB1 mRNA

NCBI chr 9:107,670,120...107,747,242
Ensembl chr 9:107,671,152...107,772,269

G

mitogen-activated protein kinase 1

decreases phosphorylation
decreases expression

Nicotine results in decreased phosphorylation of MAPK1 protein
Nicotine results in decreased expression of MAPK1 mRNA

NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513

G

mitogen-activated protein kinase 3

decreases phosphorylation
decreases expression

Nicotine results in decreased phosphorylation of MAPK3 protein
Nicotine results in decreased expression of MAPK3 mRNA

NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567

G

mitogen-activated protein kinase 8

decreases phosphorylation
decreases expression

Nicotine results in decreased phosphorylation of MAPK8 protein
Nicotine results in decreased expression of MAPK8 mRNA

NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,108,874

G

matrix metallopeptidase 9

increases expression

Nicotine results in increased expression of MMP9 mRNA

NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788

G

occludin

decreases expression

Nicotine results in decreased expression of OCLN mRNA

NCBI chr16:47,600,175...47,652,435
Ensembl chr16:47,600,212...47,654,033

G

ribonuclease P/MRP subunit p38

decreases expression

Nicotine results in decreased expression of RPP38 mRNA

NCBI chr10:46,720,135...46,725,962
Ensembl chr10:46,717,197...46,725,920

ageladine A

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

casein kinase 1 alpha 1

decreases activity
affects activity

Ageladine A analog results in decreased activity of CSNK1A1 protein
Ageladine A affects the activity of CSNK1A1 protein

NCBI chr 2:150,612,845...150,662,431
Ensembl chr 2:150,612,077...150,662,284

arecoline

term browser

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Object Name

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Evidence

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Source

PubMed Reference(s)

RGD Reference(s)

Position

G

fibronectin 1

multiple interactions
increases expression

pyrazolanthrone inhibits the reaction [Arecoline results in increased expression of FN1 protein]

NCBI chr15:117,658,158...117,737,145
Ensembl chr15:117,658,099...117,731,014

G

serpin family E member 1

increases expression
multiple interactions

Arecoline results in increased expression of SERPINE1 protein
pyrazolanthrone inhibits the reaction [Arecoline results in increased expression of SERPINE1 protein]

NCBI chr 3:8,863,738...8,871,572
Ensembl chr 3:8,863,695...8,871,547

G

transforming growth factor beta 1

multiple interactions
increases expression

Arecoline results in increased secretion of and results in increased activity of TGFB1 protein; pyrazolanthrone inhibits the reaction [Arecoline results in increased expression of TGFB1 mRNA]

NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046

brucine

term browser

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Object Name

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Evidence

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PubMed Reference(s)

RGD Reference(s)

Position

G

cholinergic receptor muscarinic 2

multiple interactions

brucine analog promotes the reaction [N-Methylscopolamine binds to CHRM2 protein]

NCBI chr18:12,455,139...12,600,314
Ensembl chr18:12,455,145...12,600,186

caffeine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ryanodine receptor 1

increases activity
multiple interactions

Caffeine results in increased activity of RYR1 protein; Caffeine results in increased activity of RYR1 protein mutant form
Caffeine promotes the reaction [Ryanodine binds to RYR1 protein mutant form]; Caffeine promotes the reaction [Ryanodine binds to RYR1 protein]; Dantrolene inhibits the reaction [Caffeine promotes the reaction [Ryanodine binds to RYR1 protein mutant form]]; Dantrolene inhibits the reaction [Caffeine promotes the reaction [Ryanodine binds to RYR1 protein]]; Dantrolene inhibits the reaction [Caffeine results in increased activity of RYR1 protein mutant form]; Dantrolene inhibits the reaction [Caffeine results in increased activity of RYR1 protein]

NCBI chr 6:47,339,759...47,458,457
Ensembl chr 6:47,343,768...47,458,458

cocaine

term browser

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Object Name

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PubMed Reference(s)

RGD Reference(s)

Position

G

endothelin 1

increases expression
multiple interactions

Cocaine results in increased expression of EDN1 protein
1,3-ditolylguanidine inhibits the reaction [Cocaine results in increased expression of EDN1 protein]; Haloperidol inhibits the reaction [Cocaine results in increased expression of EDN1 protein]

NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348

cylindrospermopsin

term browser

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Object Name

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Evidence

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Source

PubMed Reference(s)

RGD Reference(s)

Position

G

albumin

decreases uptake

cylindrospermopsin results in decreased uptake of ALB protein

NCBI chr 8:69,643,427...69,663,152
Ensembl chr 8:69,531,487...69,721,696

G

ATPase Na+/K+ transporting subunit alpha 1

increases expression

cylindrospermopsin results in increased expression of ATP1A1 mRNA

NCBI chr 4:104,353,506...104,384,321
Ensembl chr 4:104,353,508...104,384,547

G

DAB adaptor protein 2

decreases expression

cylindrospermopsin results in decreased expression of DAB2 mRNA

NCBI chr16:24,590,638...24,776,937
Ensembl chr16:24,590,645...24,646,122

G

LDL receptor related protein 2

decreases expression

cylindrospermopsin results in decreased expression of LRP2 mRNA

NCBI chr15:75,565,299...75,754,604
Ensembl chr15:75,565,303...75,716,694

himbacine

term browser

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Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cholinergic receptor muscarinic 4

multiple interactions

himbacine inhibits the reaction [Quinuclidinyl Benzilate binds to CHRM4 protein]

NCBI chr 2:16,119,794...16,131,080
Ensembl chr 2:16,122,704...16,130,810

melatonin

term browser

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Object Name

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Evidence

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Source

PubMed Reference(s)

RGD Reference(s)

Position

G

AKT serine/threonine kinase 1

multiple interactions

Melatonin inhibits the reaction [deoxynivalenol results in decreased phosphorylation of AKT1 protein]

G

ARB2 cotranscriptional regulator A

multiple interactions

Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of ARB2A mRNA]

NCBI chr 2:100,477,770...100,893,594
Ensembl chr 2:100,477,775...100,893,580

G

autophagy related 5

multiple interactions

Melatonin inhibits the reaction [deoxynivalenol results in increased expression of ATG5 protein]

NCBI chr 1:72,343,950...72,520,402
Ensembl chr 1:72,270,799...72,520,396

G

BCL2 associated X, apoptosis regulator

multiple interactions

Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of BAX mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of BAX protein]

NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140

G

BCL2 apoptosis regulator

multiple interactions
increases expression

Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]; Melatonin inhibits the reaction [Malathion results in decreased expression of BCL2 mRNA]
Melatonin results in increased expression of BCL2 mRNA

PMID:31535366 PMID:37120089

NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879

G

beclin 1

increases expression
multiple interactions

Melatonin results in increased expression of BECN1 protein
Melatonin inhibits the reaction [deoxynivalenol results in increased expression of BECN1 protein]

NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373

G

caspase 3

decreases expression
multiple interactions

Melatonin results in decreased expression of CASP3 mRNA
Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP3 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP3 protein]

PMID:31535366 PMID:35665993

NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213

G

caspase 8

multiple interactions

Melatonin inhibits the reaction [tetrabromobisphenol A results in decreased expression of CASP8 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in decreased expression of CASP8 protein]

NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468

G

caspase 9

multiple interactions

Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP9 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP9 protein]

NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007

G

catalase

multiple interactions
increases activity

Melatonin inhibits the reaction [deoxynivalenol results in decreased activity of CAT protein]; Melatonin inhibits the reaction [Malathion results in decreased expression of CAT mRNA]
Melatonin results in increased activity of CAT protein

PMID:31535366 PMID:37120089

NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452

G

component of inhibitor of nuclear factor kappa B kinase complex

multiple interactions

Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of CHUK mRNA]

NCBI chr14:111,316,178...111,351,669
Ensembl chr14:111,315,141...111,351,868

G

claudin 1

multiple interactions
increases expression

Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]
Melatonin results in increased expression of CLDN1 protein

NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657

G

cytochrome c oxidase subunit 7A2 like

multiple interactions

Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of COX7A2L mRNA]

NCBI chr 3:97,951,115...97,983,309
Ensembl chr 3:97,951,114...97,983,309

G

glutathione peroxidase 4

increases expression

Melatonin results in increased expression of GPX4 mRNA

NCBI chr 2:77,321,568...77,323,931
Ensembl chr 2:77,320,464...77,323,931

G

interleukin 18

multiple interactions

Melatonin inhibits the reaction [deoxynivalenol results in increased expression of IL18 mRNA]

NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219

G

interleukin 6

multiple interactions

Melatonin inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]

NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263

G

KLF transcription factor 5

multiple interactions

Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of KLF5 mRNA]

NCBI chr11:45,370,009...45,386,673
Ensembl chr11:45,369,810...45,388,314

G

interleukin-1 beta-like

multiple interactions

Melatonin inhibits the reaction [deoxynivalenol results in increased expression of IL1B protein]

G

microtubule associated protein 1 light chain 3 beta

multiple interactions

Melatonin affects the reaction [deoxynivalenol results in increased expression of and results in increased lipidation of MAP1LC3B protein]

NCBI chr 6:1,919,879...1,941,069
Ensembl chr 6:1,915,387...1,941,069

G

mitogen-activated protein kinase kinase 1

multiple interactions

Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of MAP2K1 mRNA]

NCBI chr 1:164,381,892...164,469,313
Ensembl chr 1:164,381,845...164,471,226

G

mixed lineage kinase domain like pseudokinase

multiple interactions

Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of MLKL mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of MLKL protein]

NCBI chr 6:12,923,846...12,951,176
Ensembl chr 6:12,924,894...12,951,173

G

mechanistic target of rapamycin kinase

multiple interactions
decreases phosphorylation

Melatonin inhibits the reaction [deoxynivalenol results in decreased phosphorylation of MTOR protein]
Melatonin results in decreased phosphorylation of MTOR protein

NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888

G

occludin

multiple interactions

Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of OCLN protein]

NCBI chr16:47,600,175...47,652,435
Ensembl chr16:47,600,212...47,654,033

G

perilipin 2

multiple interactions

Melatonin inhibits the reaction [Malathion results in decreased expression of PLIN2 mRNA]; Melatonin inhibits the reaction [Malathion results in decreased expression of PLIN2 protein]

NCBI chr 1:203,683,867...203,709,277
Ensembl chr 1:203,683,862...203,709,273

G

peroxisome proliferator activated receptor gamma

multiple interactions

Melatonin inhibits the reaction [Malathion results in decreased expression of PPARG mRNA]; Melatonin inhibits the reaction [Malathion results in decreased expression of PPARG protein]

NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,322...68,433,944

G

phosphatase and tensin homolog

multiple interactions

Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of PTEN mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of PTEN protein]

NCBI chr14:99,929,590...100,021,619

G

receptor interacting serine/threonine kinase 1

multiple interactions

Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK1 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK1 protein]

NCBI chr 7:1,841,143...1,880,705
Ensembl chr 7:1,841,239...1,880,699

G

receptor interacting serine/threonine kinase 3

multiple interactions

Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK3 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK3 protein]

NCBI chr 7:74,951,145...74,955,255
Ensembl chr 7:74,951,145...74,955,251

G

superoxide dismutase 2

increases expression
multiple interactions

Melatonin results in increased expression of SOD2 mRNA
Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of SOD2 mRNA]

PMID:31535366 PMID:37120089

NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560

G

tight junction protein 1

increases expression
multiple interactions

Melatonin results in increased expression of TJP1 protein
Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of TJP1 protein]

NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,370...145,195,836

G

tumor necrosis factor

multiple interactions

Melatonin inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]

NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416

G

tumor protein p53

multiple interactions
decreases expression

Melatonin inhibits the reaction [Malathion results in increased expression of TP53 mRNA]
Melatonin results in decreased expression of TP53 mRNA

NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818

G

ZFP36 ring finger protein like 2

multiple interactions

Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of ZFP36L2 mRNA]

NCBI chr 3:97,200,395...97,203,094
Ensembl chr 3:97,200,407...97,204,698

mesulergine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

5-hydroxytryptamine receptor 2C

affects binding
multiple interactions

mesulergine binds to HTR2C protein
8-fluoro-12-(4-methylpiperazin-1-yl)-6H-(1)benzothieno(2,3-b)(1,5)benzodiazepine inhibits the reaction [mesulergine binds to HTR2C protein]

NCBI chr X:94,053,415...94,313,352
Ensembl chr X:94,053,456...94,313,355

monocrotaline

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ornithine decarboxylase 1

increases activity
increases expression

Monocrotaline results in increased activity of ODC1 protein
Monocrotaline results in increased expression of ODC1 mRNA

NCBI chr 3:126,087,013...126,095,644
Ensembl chr 3:126,087,242...126,096,051

G

tenascin C

multiple interactions
increases expression

1,3-dimethylthiourea inhibits the reaction [Monocrotaline results in increased expression of TNC mRNA]

NCBI chr 1:255,533,235...255,630,381
Ensembl chr 1:255,533,238...255,630,376

nicotinamide

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

forkhead box O1

increases expression

Niacinamide results in increased expression of FOXO1 mRNA

NCBI chr11:15,317,222...15,410,059
Ensembl chr11:15,317,124...15,410,473

G

peroxisome proliferator activated receptor gamma

increases expression

Niacinamide results in increased expression of PPARG mRNA

NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,322...68,433,944

G

sirtuin 1

decreases expression

Niacinamide results in decreased expression of SIRT1 mRNA

NCBI chr14:71,091,167...71,126,351
Ensembl chr14:71,091,167...71,123,297

nicotine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adenylate cyclase activating polypeptide 1

multiple interactions

Nicotine inhibits the reaction [[Carbon Dioxide co-treated with Oxygen deficiency] results in decreased expression of ADCYAP1 protein]

NCBI chr 6:105,414,628...105,422,294
Ensembl chr 6:105,414,631...105,422,294

G

ADCYAP receptor type I

decreases expression

Nicotine results in decreased expression of ADCYAP1R1 protein

NCBI chr18:41,915,180...41,972,327
Ensembl chr18:41,917,428...41,972,301

G

anti-Mullerian hormone

decreases expression
decreases secretion

Nicotine results in decreased expression of AMH mRNA
Nicotine results in decreased secretion of AMH protein

NCBI chr 2:76,415,564...76,418,315
Ensembl chr 2:76,414,427...76,418,312

G

BCL2 apoptosis regulator

decreases expression

Nicotine results in decreased expression of BCL2 mRNA

NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879

G

cholinergic receptor nicotinic alpha 2 subunit

multiple interactions

Nicotine affects the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNA2 protein]

NCBI chr14:11,193,732...11,204,334
Ensembl chr14:11,195,228...11,207,650

G

cholinergic receptor nicotinic alpha 3 subunit

multiple interactions

Nicotine affects the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNA3 protein]

NCBI chr 7:47,361,710...47,382,743
Ensembl chr 7:47,361,899...47,384,303

G

cholinergic receptor nicotinic alpha 7 subunit

multiple interactions

Nicotine affects the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNA7 protein]

NCBI chr 1:142,803,697...142,937,124
Ensembl chr 1:142,803,701...142,937,123

G

cholinergic receptor nicotinic alpha 9 subunit

multiple interactions

Nicotine affects the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNA9 protein]

NCBI chr 8:31,430,933...31,456,385
Ensembl chr 8:31,443,043...31,456,384

G

cholinergic receptor nicotinic beta 2 subunit

multiple interactions

Nicotine affects the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNB2 protein]

NCBI chr 4:95,196,992...95,211,084
Ensembl chr 4:95,198,717...95,211,037

G

cytochrome P450 19A3

decreases expression

Nicotine results in decreased expression of CYP19A1 mRNA

NCBI chr 1:120,476,890...120,556,103
Ensembl chr 1:120,367,667...120,695,899

G

follicle stimulating hormone receptor

decreases expression

Nicotine results in decreased expression of FSHR mRNA

NCBI chr 3:91,607,236...91,775,255
Ensembl chr 3:91,607,305...91,774,683

G

inhibin subunit beta B

decreases expression
decreases secretion

Nicotine results in decreased expression of INHBB mRNA
Nicotine results in decreased secretion of INHBB protein

NCBI chr15:30,999,994...31,004,405
Ensembl chr15:30,999,520...31,004,405

G

integrin subunit beta 1

decreases expression

Nicotine results in decreased expression of ITGB1 mRNA

NCBI chr10:56,078,393...56,130,608
Ensembl chr10:56,078,396...56,173,326

G

laminin subunit beta 1

decreases expression

Nicotine results in decreased expression of LAMB1 mRNA

NCBI chr 9:107,670,120...107,747,242
Ensembl chr 9:107,671,152...107,772,269

G

mitogen-activated protein kinase 1

decreases expression
decreases phosphorylation

Nicotine results in decreased expression of MAPK1 mRNA
Nicotine results in decreased phosphorylation of MAPK1 protein

NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513

G

mitogen-activated protein kinase 3

decreases phosphorylation
decreases expression

Nicotine results in decreased phosphorylation of MAPK3 protein
Nicotine results in decreased expression of MAPK3 mRNA

NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567

G

mitogen-activated protein kinase 8

decreases expression
decreases phosphorylation

Nicotine results in decreased expression of MAPK8 mRNA
Nicotine results in decreased phosphorylation of MAPK8 protein

NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,108,874

G

matrix metallopeptidase 9

increases expression

Nicotine results in increased expression of MMP9 mRNA

NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788

G

occludin

decreases expression

Nicotine results in decreased expression of OCLN mRNA

NCBI chr16:47,600,175...47,652,435
Ensembl chr16:47,600,212...47,654,033

G

ribonuclease P/MRP subunit p38

decreases expression

Nicotine results in decreased expression of RPP38 mRNA

NCBI chr10:46,720,135...46,725,962
Ensembl chr10:46,717,197...46,725,920

physostigmine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acetylcholinesterase

decreases activity
multiple interactions

Physostigmine results in decreased activity of ACHE protein
Physostigmine inhibits the reaction [Soman results in decreased activity of ACHE protein]

NCBI chr 3:8,732,451...8,738,274
Ensembl chr 3:8,732,441...8,738,605

ryanodine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ryanodine receptor 1

affects binding
multiple interactions

Ryanodine binds to RYR1 protein; Ryanodine binds to RYR1 protein mutant form
5'-adenylyl (beta,gamma-methylene)diphosphonate affects the reaction [Ryanodine binds to RYR1 protein]; Caffeine promotes the reaction [Ryanodine binds to RYR1 protein mutant form]; Caffeine promotes the reaction [Ryanodine binds to RYR1 protein]; Dantrolene inhibits the reaction [Caffeine promotes the reaction [Ryanodine binds to RYR1 protein mutant form]]; Dantrolene inhibits the reaction [Caffeine promotes the reaction [Ryanodine binds to RYR1 protein]]; Dantrolene inhibits the reaction [Ryanodine binds to RYR1 protein mutant form]; Dantrolene inhibits the reaction [Ryanodine binds to RYR1 protein]; Dantrolene inhibits the reaction [Strontium promotes the reaction [Ryanodine binds to RYR1 protein]]; Strontium promotes the reaction [Ryanodine binds to RYR1 protein mutant form]; Strontium promotes the reaction [Ryanodine binds to RYR1 protein]

NCBI chr 6:47,339,759...47,458,457
Ensembl chr 6:47,343,768...47,458,458

G

ryanodine receptor 2

affects binding

Ryanodine binds to RYR2 protein

NCBI chr14:53,652,140...54,406,691
Ensembl chr14:53,652,485...54,192,063

serotonin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression
multiple interactions

Serotonin results in increased expression of FOS mRNA; Serotonin results in increased expression of FOS protein
sarpogrelate inhibits the reaction [Serotonin results in increased expression of FOS mRNA]; sarpogrelate inhibits the reaction [Serotonin results in increased expression of FOS protein]

NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554

G

Jun proto-oncogene, AP-1 transcription factor subunit

multiple interactions
increases expression

sarpogrelate inhibits the reaction [Serotonin results in increased expression of JUN mRNA]; sarpogrelate inhibits the reaction [Serotonin results in increased expression of JUN protein]
Serotonin results in increased expression of JUN mRNA; Serotonin results in increased expression of JUN protein

NCBI chr 6:153,686,425...153,687,635
Ensembl chr 6:153,685,682...153,687,636

G

mitogen-activated protein kinase 1

increases phosphorylation
multiple interactions

Serotonin results in increased phosphorylation of MAPK1 protein
sarpogrelate inhibits the reaction [Serotonin results in increased phosphorylation of MAPK1 protein]

NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513

G

mitogen-activated protein kinase 3

multiple interactions
increases phosphorylation

sarpogrelate inhibits the reaction [Serotonin results in increased phosphorylation of MAPK3 protein]

NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567

strychnine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cholinergic receptor muscarinic 2

multiple interactions

Strychnine analog promotes the reaction [N-Methylscopolamine binds to CHRM2 protein]

NCBI chr18:12,455,139...12,600,314
Ensembl chr18:12,455,145...12,600,186

tubocurarine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

tachykinin precursor 1

affects activity

Tubocurarine affects the activity of TAC1 protein

NCBI chr 9:77,197,403...77,206,529
Ensembl chr 9:77,197,536...77,206,523

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	5066
role	5030
biological role	5030
biochemical role	4951
metabolite	4939
alkaloid	74
(+)-Aspidospermidine	0
(+)-Erythraline	0
(+)-Norushinsunine N-oxide	0
(+)-Quebrachidine	0
(+)-Setoclavine	0
(+)-aplysinillin	0
(+/-)-gamma-Lycorane	0
(-)-12beta-Hydroxylsophocarpine	0
(-)-Alstolucine A, (rel)-	0
(-)-Alstolucine B, (rel)-	0
(-)-Alstolucine C	0
(-)-Alstolucine D, (rel)-	0
(-)-Alstolucine E	0
(-)-Alstolucine F	0
(-)-Apparicine	0
(-)-Ormosanine	0
(-)-Pyrifolidine	0
(-)-Quebrachamine	0
(-)-antofine	0
(-)-demecolcine	0
(-)-dibromophakellin	0
(13R,14E)-14-Ethylidene-12-methylidene-1,10-diazatetracyclo[11.2.2.03,11.04,9]heptadeca-3(11),4,6,8-tetraene	0
(1R,1'R,10S,11S,12S,13'S,14'R)-12,14'-Diethylspiro[8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6,8-tetraene-10,10'-8,16-diazahexacyclo[11.5.2.11,8.02,7.016,19.012,21]henicosa-2,4,6,12(21)-tetraene]	0
(1R,13S,14E,19S,21S)-10-[(1R,12S,13R,14E,17R,19S,21S)-14-Ethylidene-9-oxo-8,16-diazahexacyclo[11.5.2.11,8.02,7.016,19.012,21]henicosa-2,4,6,10-tetraen-17-yl]-14-(2-hydroxyethylidene)-8,16-diazahexacyclo[11.5.2.11,8.02,7.016,19.012,21]henicosa-2,4,6,11-tetraen-9-one	0
(1R,15R,17S)-17-Ethyl-6-[(1R,14R,15E)-15-ethylidene-17,18-dimethyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraen-12-yl]-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraene	0
(1R,2R,12R,14S)-9-Methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraene-2,14-diol	0
(1R,2S,6S,11S,13R,14R,21R)-7,19,23-Triazahexacyclo[9.9.1.11,13.12,6.07,21.014,19]tricosane	0
(1R,9R)-5-Cyclohexyl-11-(propylsulfonyl)-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one	0
(1S,15S,18S,19S,20S)-N-[2-(4-aminophenyl)ethyl]-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxamide	0
(1S,9R,10R,12S)-12-Hydroxy-7,15-diazatetracyclo[7.7.1.02,7.010,15]heptadeca-2,4-dien-6-one	0
(2'S)-Hydroxy-(11S,12R)-dihydrostemofoline, (rel)-	0
(2'S)-Hydroxystemofoline	0
(2R,3R,11Bs)-2-[(6,7-dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl]-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinoline	0
(2R,3S,11bR)-2-[[(1S)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl]-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine	0
(2S,3R)-2-[(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl]-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine	0
(2S,3R)-2-[[(1R)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl]-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine	0
(4aR,5aS,8aR,15bR)-10,11-dimethoxy-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinoline-14-one	0
(4aR,8aR,15bR)-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinoline-14-one	0
(7S)-7-acetamido-1,2,3-trimethoxy-6,7-dihydro-5H-dibenzo[5,3-b:1',2'-e][7]annulene-9-carboxylic acid	0
(7S,14S)-(-)-7-Methyl-10-O-demethylxylopinine	0
(8S,Z)-6-((2R,E)-6-hydroxy-2,5-dimethylhept-4-en-1-ylidene)-8-methyloctahydroindolizin-8-ol	0
(E)-Avenanthramide D	0
(R,S)-Scoulerine	0
(S)-1-hydroxy-N-methylcanadine +	0
(S)-colchicine	1
1',2'-didehydrostemofoline	0
1,2-O-Diacetylzephyranthine	0
1-O-Acetyllycorine	0
1-[(1R,9S,11R,12E,17S)-12-Ethylidene-10-(hydroxymethyl)-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6-trien-8-yl]ethanone	0
1-hydroxyprotostemonine, (rel)-	0
1-methoxy-5R,10S-agroclavine	0
10-alpha-methoxy-9,10-dihydrolysergol	0
11-(Methylthiono)canthin-6-one	0
11-Hydroxytubotaiwine	0
11-Hydroxyvittatine	0
11-Methoxyduguesuramine	0
11-Methoxysampangine	0
11-beta-hydroxy-beta-saxitoxinol(2+)	0
11-beta-hydroxysaxitoxin(2+)	0
12-Ethylidene-6-hydroxy-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2(7),3,5,9-tetraene-10-carbaldehyde	0
13-O-Acetylbaptifoline	0
13-Oxocryptopine	0
14,15-Dehydro-16-epi-vincamine	0
14,19-Didehydrocondyfolan	0
14,19-Dihydroaspidospermatine	0
14-norpseurotin A	0
15-hydroxyangustilobine A	0
16-Ethoxystrychnine	0
16-Propoxystrychnine	0
16-epivincamine	0
16R,19E-isositsirikine	0
18-Epiormosanine	0
18-Hydroxy-11,17-dimethoxyyohimban-16-carboxylic acid	0
19,20-E-vallesamine	0
19-Acetyltabersonine	0
19-Hydroxytabersonine	0
2'-hydroxystemofoline	0
2,3,9,10-Tetrahydroxyberberine	0
2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline	0
2-(8-Oxo-1,5,6,8-tetrahydro-2H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(4H)-yl)acetamide	0
2-Bromo-5-hydroxy-N-[2-(4-hydroxyphenyl)ethyl]-4-methoxy-N-methylbenzamide	0
2-Methoxycanthin-6-one	0
2-\{[(2E)-3-(3,4-dihydroxyphenyl)-1-hydroxyprop-2-en-1-ylidene]amino\}-5-hydroxybenzoic acid	0
2-phenylethylamine +	0
2-propylpiperidine	0
20(R)-tubotaiwine	0
20(S)-tubotaiwine	0
20-Epi-19,20-dihydro-decarbomethoxy vobasine	0
2alpha-(2'-pyrrolyl)-4alpha-methoxycarbonyl-5beta-[(2''-methyl)-heptyl]-1,3-oxazacyclohexane	0
3,4-dimethoxyphenylethylamine	0
3,9-dimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,10-diol	0
3-(4-methoxyphenyl)-3-[[2-(4-methoxyphenyl)-1-oxoethyl]amino]propanoic acid	0
3-(6-chloro-3-pyridinyl)-7-azabicyclo[2.2.1]heptane	0
3-Acetylnerbowdine	0
3-Epidemissidine	0
3-Epifortuneine	0
3-Epimacronine	0
3-Epischelhammericine	0
3-O-Acetylhamayne	0
4-(Methylthio)canthin-6-one	0
4-Hydroxycanthin-6-one	0
5-(Methylthio)canthin-6-one	0
5-Hydroxy-4-methoxy-3-methyl-2,6-canthinedione	0
5-Methoxycanthin-6-one	0
5-bromo-8-methoxy-1-methyl-beta-carboline	0
6,7-seco-Agroclavine	0
6-hydroxymanzamine A	0
7-Hydroxymitragynine	0
7-epi-cylindrospermopsin	0
8-Benzyl-9,10-dimethoxy-5,8-dihydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline	0
8-Oxoerythraline_epoxide	0
8-[(2S,4R,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-1-hydroxy-5-methoxy-3-methyl-6-[(3S)-2-oxopiperidin-3-yl]-5H-benzo[b]phenanthridine-7,12-dione	0
8-hydroxymanzamine A	0
8-oxoerythraline	0
9-(Methylthio)canthin-6-one	0
9-O-Demethyl-2alpha-hydroxyhomolycorine	0
9-O-Demethylhomolycorine	0
9-deacetylfumigaclavine C	0
9-deoxycurtisin	0
Acutumidine	0
Acutumine	0
Affinine	0
Agroclavine I	0
Akuammine	0
Albomaculine	0
Alkaloid RC	0
Allopumiliotoxin 267a	0
Aloperine	0
Alpinine	0
Amalorin	0
Amatain	0
Ambelline	0
Ammothamnine	0
Anagyrine	0
Apovincamine	0
Argentine	0
Aristolactam AII	0
Aspidospermatine	0
Atherosperminine	0
Avenanthramide 1c	0
Avenanthramide 1p	0
Avenanthramide 2	0
Avenanthramide E	0
Baloxine	0
Baptifoline	0
Berberastine	0
Berberrubine	0
Bonafousine	0
Brovincamine fumarate	0
C-Curarine	0
Calebassone	0
Candimine	0
Capaurine	0
Caracurine V	0
Caribine	0
Caseadine	0
Catharanthine hcl	0
Catharanthine hemitartrate	0
Catharine	0
Caulophylline	0
Cavinine	0
Cevadine	0
Chanoclavine II	0
Cocculolidine	0
Coccutrine	0
Colchicoside	0
Coptisine chloride	0
Coreximine	0
Corynantheidine	0
Costaclavine	0
Crinamidine	0
Crinamine	0
Crinine	0
Cularicine	0
Cularidine	0
Cularimine	0
Cularine	0
Curtisin	0
Cycloclavine	0
D-Tetrahydropalmatine	0
Deacetylcolchicine	0
Decorticasine	0
Dehydrocorydaline	0
Dehydrocorydalmine	0
Dehydrocorytenchine	0
Delavine	0
Demissidine	0
Desmethylemetine	0
Didehydrostemofoline	0
Dihydrocorynantheine	0
Dihydrolycorine	0
Dihydrosetoclavine	0
Dimethamine	0
Dubiusine	0
Duguetine	0
Eburnamenin-14(15H)-one	0
Eburnamine	0
Eburnamonine	0
Elymoclavine	0
Epoxyagroclavine I	0
Erysonine	0
Erysothiopine	0
Erysotrine	0
Erythratidine	0
Erythratine	0
Erythrina alkaloid +	0
Fawcettidine	0
Floramultine	0
Fumigaclavine D	0
Fumigaclavine E	0
Fumigaclavine F	0
Fumigaclavine G	0
Fumigaclavine H	0
Gabunamine	0
Germerine	0
Germine	0
Glaudine	0
Glaziovine	0
Haemanthamine	0
Haemanthidine	0
Hamayne	0
Harringtonine	0
Hirsuteine	0
Homoormosanine	0
Imperialine	0
Isococculidine	0
Isomatrine	0
Isorheagenine	0
Jamine	0
Jatrorrhizine	0
Kreysigine	0
L-proline betaine	0
LSM-1309	0
LSM-1372	0
LSM-1597	0
LSM-16753	0
LSM-18556	0
LSM-1944	0
LSM-22634	0
LSM-24185	0
LSM-4236	0
LSM-4502	0
LSM-5249	0
LSM-6354	0
LSM-6387	0
LSM-6464	0
LSM-6667	0
Lambertine	0
Lycoflexine	0
Lycorenine	0
Matrine	0
Mecambrine	0
Methyl (15R,17S,18S)-17-ethyl-7-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraene-1-carboxylate	0
Methyl (1R,11S,17S)-12-ethylidene-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6,9-tetraene-10-carboxylate	0
Methyl (1R,12S,20R)-12-ethyl-14-oxa-8,17-diazahexacyclo[10.7.1.01,9.02,7.013,15.017,20]icosa-2,4,6,9-tetraene-10-carboxylate	0
Methyl (1R,9S,11S,14E,15S,17S)-19-(acetyloxymethyl)-14-ethylidene-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate	0
Methyl (1S,10R,12R,19S)-12-ethyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,13-tetraene-10-carboxylate	0
Methyl (1S,15E)-15-ethylidene-12-oxo-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate	0
Methyl (Z)-2-[(3E,12bS)-3-ethylidene-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-hydroxyprop-2-enoate	0
Methyl 12-ethyl-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,13-tetraene-10-carboxylate	0
Methyl 17-(1-hydroxyethyl)-7-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraene-1-carboxylate	0
Methyl 2-(3-ethenyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl)-3-methoxyprop-2-enoate	0
Methyl 2-(3-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl)-3-methoxyprop-2-enoate	0
Methyl 2-(3-ethyl-7a-hydroxy-8-methoxy-2,3,4,6,7,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl)-3-methoxyprop-2-enoate	0
N(4)-demethyl-12-methoxyalstogustine	0
N-(lysergyl-isoleucyl)-cyclo(phenylalanyl-prolyl)	0
N-Acetylcytisine	0
N-Acetylloline	0
N-Formyldemecolcine	0
N-Formylnorloline	0
N-Methyl-14-O-demethylepiporphyroxine	0
N-Methylcanadium (iodide)	0
N-Methylloline	0
N-[2-(3,4-diethoxyphenyl)ethyl]-4-phenoxybenzamide	0
N-acetylnorloline	0
N-formylloline	0
N-methylcheilanthifoline	0
N-methylnicotinate	0
N-methylphenylethanolamine	0
Nigerrimin B	0
Nobilisitine A	0
O-Methyllycorenine	0
Oxysophocarpine	0
Paliclavine	0
Panamine	0
Paspaclavine	0
Peimisine	0
Phellodendrine	0
Piperolactam A	0
Piperolactam C	0
Piperolactam D	0
Piptanthine	0
Pretazettine	0
Promucosine	0
Protoveratrine A	0
Protoveratrine B	0
Protoverine	0
Pseudocolumbamine	0
Pseudopalmatine	0
Psychotrin	0
Pumiliotoxin 251D	0
Pumiliotoxin A	0
Pyroclavine	0
Rhoeadine	0
Rhombifoline	0
Roquefortine A	0
Roxburghine B	0
Scholaricine	0
Serratanidine	0
Serratine	0
Sinactine	0
Sipeimine	0
Sophocarpine	0
Sophoranol	0
Spinosine	0
Tabernamine	0
Tabernanthine	0
Templetine	0
Thermospine	0
Tinctorine	0
Toxiferine I	0
Verticine	0
Vinpocetine	0
Worenine	0
Xylopinine	0
Zephyranthine	0
Zhebeinine	0
Zygadenine	0
[(6Ar,9R,10S,10aR)-7,9-dimethyl-5-(2-methylbut-3-en-2-yl)-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinolin-10-yl] acetate	0
acetylcaranine	0
acremolin B	0
acronycine	0
ageladine A	1
alamarine	0
alkaloid antibiotic +	0
alkaloid ester +	0
angustilobine B, (rac)-	0
annomontine	0
ascidiathiazone A	0
ascidiathiazone B	0
aspernidine A	0
aspernigrin A +	0
asperparaline A	0
batzelladine A	0
batzelladine B	0
benzazepine alkaloid +	0
benzodiazepine alkaloid	0
beta,beta-ergoannam	0
beta-ergokryptam	0
beta-saxitoxinol(2+)	0
betalain +	0
biindole alkaloid +	0
bisindole alkaloid +	0
brovincamine	0
carbazole alkaloid +	0
carpaine	0
caulophine	0
ceratamine A	0
ceratamine B	0
cheilanthifoline	0
circumdatin H	0
colchicine +	1
coptisine	0
crambescidin 401	0
crambescidin 800	0
crambescidin 826	0
croomine	0
cryptopleurine	0
cylindrospermopsin	4
cystodytin D +	0
cystodytin E +	0
cystodytin F	0
cystodytin G	0
cytisine	0
cytochalasan alkaloid +	0
cytochalasin D	0
decahydroquinoline alkaloid +	0
decarbamoylsaxitoxin	0
deoxycylindrospermopsin	0
ent-6alpha-Hydroxybuphanisine	0
ent-6beta-Hydroxybuphanisine	0
epibatidine	0
ergoline alkaloid +	1
feruloylagmatine +	0
ficellomycin	0
glycoalkaloid +	0
gravacridonediol	0
harmala alkaloid +	0
hederacine A	0
hederacine B	0
herquline A	0
herquline B	0
herquline C	0
indirubin-3'-monoxime	0
indole alkaloid +	40
indolizidine alkaloid +	0
isoquinoline alkaloid +	1
karakoline	0
lamellarin alpha 20-hydrogen sulfate	0
leuconoxine	0
lycojapodine A	0
lycoperine A	0
lymphostin	0
manzamine A +	0
massadine	0
methyl (1S,12S,13E)-13-ethylidene-18-(hydroxymethyl)-4-methoxy-8,15-diazapentacyclo[10.5.1.01,9.02,7.010,15]octadeca-2(7),3,5,8-tetraene-18-carboxylate	0
monoamine alkaloid +	0
muscimol	0
neosaxitoxin	0
neotuberostemonine	0
nigerazine A	0
nigerazine B	0
nigragillin	0
nitensidine E	0
nostocarboline	0
oriciacridone C	0
oriciacridone F	0
oxyprotostemonine	0
paralytic shellfish toxin +	0
penipanoid B	0
phenanthrene alkaloid +	0
phenethylamine alkaloid +	0
phyllospadine	0
pipercallosidine	0
pipercallosine	0
piperidine alkaloid +	1
piperlactam S	0
protostemonine	0
pseudopelletierine	0
purine alkaloid +	1
pyridine alkaloid +	26
pyrrolidine alkaloid +	20
pyrrolizidine alkaloid +	2
pyrrolizine alkaloid +	0
pyrrolnitrin	0
quinazoline alkaloid +	0
quinoline alkaloid +	1
quinolizidine alkaloid +	0
rohitukine	0
ryanodine	2
sampangine	0
saxitoxin +	0
solanid-5-en-3-ol +	0
spermidine alkaloid +	0
spirosolane +	0
stemofoline	0
steroid alkaloid +	0
syncarpamide	0
terpene alkaloid +	0
tetrahydrocolumbamine	0
tetramethylpyrazine	0
thalictricavine	0
tropane alkaloid +	1
tuberostemonine	0
tuberostemonine N	0
undecylprodigiosin	0
veracevine	0
vinervine	0
xestospongin C	0
zarzissine	0
Path 2
Term	Annotations
CHEBI ontology	5066
subatomic particle	5057
composite particle	5057
hadron	5057
baryon	5057
nucleon	5057
atomic nucleus	5057
atom	5057
main group element atom	5026
main group molecular entity	5025
p-block molecular entity	5023
carbon group molecular entity	4940
organic molecular entity	4939
heteroorganic entity	4779
organonitrogen compound	382
alkaloid	74
(+)-Aspidospermidine	0
(+)-Erythraline	0
(+)-Norushinsunine N-oxide	0
(+)-Quebrachidine	0
(+)-Setoclavine	0
(+)-aplysinillin	0
(+/-)-gamma-Lycorane	0
(-)-12beta-Hydroxylsophocarpine	0
(-)-Alstolucine A, (rel)-	0
(-)-Alstolucine B, (rel)-	0
(-)-Alstolucine C	0
(-)-Alstolucine D, (rel)-	0
(-)-Alstolucine E	0
(-)-Alstolucine F	0
(-)-Apparicine	0
(-)-Ormosanine	0
(-)-Pyrifolidine	0
(-)-Quebrachamine	0
(-)-antofine	0
(-)-demecolcine	0
(-)-dibromophakellin	0
(13R,14E)-14-Ethylidene-12-methylidene-1,10-diazatetracyclo[11.2.2.03,11.04,9]heptadeca-3(11),4,6,8-tetraene	0
(1R,1'R,10S,11S,12S,13'S,14'R)-12,14'-Diethylspiro[8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6,8-tetraene-10,10'-8,16-diazahexacyclo[11.5.2.11,8.02,7.016,19.012,21]henicosa-2,4,6,12(21)-tetraene]	0
(1R,13S,14E,19S,21S)-10-[(1R,12S,13R,14E,17R,19S,21S)-14-Ethylidene-9-oxo-8,16-diazahexacyclo[11.5.2.11,8.02,7.016,19.012,21]henicosa-2,4,6,10-tetraen-17-yl]-14-(2-hydroxyethylidene)-8,16-diazahexacyclo[11.5.2.11,8.02,7.016,19.012,21]henicosa-2,4,6,11-tetraen-9-one	0
(1R,15R,17S)-17-Ethyl-6-[(1R,14R,15E)-15-ethylidene-17,18-dimethyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraen-12-yl]-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraene	0
(1R,2R,12R,14S)-9-Methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraene-2,14-diol	0
(1R,2S,6S,11S,13R,14R,21R)-7,19,23-Triazahexacyclo[9.9.1.11,13.12,6.07,21.014,19]tricosane	0
(1R,9R)-5-Cyclohexyl-11-(propylsulfonyl)-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one	0
(1S,15S,18S,19S,20S)-N-[2-(4-aminophenyl)ethyl]-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxamide	0
(1S,9R,10R,12S)-12-Hydroxy-7,15-diazatetracyclo[7.7.1.02,7.010,15]heptadeca-2,4-dien-6-one	0
(2'S)-Hydroxy-(11S,12R)-dihydrostemofoline, (rel)-	0
(2'S)-Hydroxystemofoline	0
(2R,3R,11Bs)-2-[(6,7-dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl]-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinoline	0
(2R,3S,11bR)-2-[[(1S)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl]-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine	0
(2S,3R)-2-[(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl]-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine	0
(2S,3R)-2-[[(1R)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl]-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine	0
(4aR,5aS,8aR,15bR)-10,11-dimethoxy-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinoline-14-one	0
(4aR,8aR,15bR)-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinoline-14-one	0
(7S)-7-acetamido-1,2,3-trimethoxy-6,7-dihydro-5H-dibenzo[5,3-b:1',2'-e][7]annulene-9-carboxylic acid	0
(7S,14S)-(-)-7-Methyl-10-O-demethylxylopinine	0
(8S,Z)-6-((2R,E)-6-hydroxy-2,5-dimethylhept-4-en-1-ylidene)-8-methyloctahydroindolizin-8-ol	0
(E)-Avenanthramide D	0
(R,S)-Scoulerine	0
(S)-1-hydroxy-N-methylcanadine +	0
(S)-colchicine	1
1',2'-didehydrostemofoline	0
1,2-O-Diacetylzephyranthine	0
1-O-Acetyllycorine	0
1-[(1R,9S,11R,12E,17S)-12-Ethylidene-10-(hydroxymethyl)-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6-trien-8-yl]ethanone	0
1-hydroxyprotostemonine, (rel)-	0
1-methoxy-5R,10S-agroclavine	0
10-alpha-methoxy-9,10-dihydrolysergol	0
11-(Methylthiono)canthin-6-one	0
11-Hydroxytubotaiwine	0
11-Hydroxyvittatine	0
11-Methoxyduguesuramine	0
11-Methoxysampangine	0
11-beta-hydroxy-beta-saxitoxinol(2+)	0
11-beta-hydroxysaxitoxin(2+)	0
12-Ethylidene-6-hydroxy-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2(7),3,5,9-tetraene-10-carbaldehyde	0
13-O-Acetylbaptifoline	0
13-Oxocryptopine	0
14,15-Dehydro-16-epi-vincamine	0
14,19-Didehydrocondyfolan	0
14,19-Dihydroaspidospermatine	0
14-norpseurotin A	0
15-hydroxyangustilobine A	0
16-Ethoxystrychnine	0
16-Propoxystrychnine	0
16-epivincamine	0
16R,19E-isositsirikine	0
18-Epiormosanine	0
18-Hydroxy-11,17-dimethoxyyohimban-16-carboxylic acid	0
19,20-E-vallesamine	0
19-Acetyltabersonine	0
19-Hydroxytabersonine	0
2'-hydroxystemofoline	0
2,3,9,10-Tetrahydroxyberberine	0
2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline	0
2-(8-Oxo-1,5,6,8-tetrahydro-2H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(4H)-yl)acetamide	0
2-Bromo-5-hydroxy-N-[2-(4-hydroxyphenyl)ethyl]-4-methoxy-N-methylbenzamide	0
2-Methoxycanthin-6-one	0
2-\{[(2E)-3-(3,4-dihydroxyphenyl)-1-hydroxyprop-2-en-1-ylidene]amino\}-5-hydroxybenzoic acid	0
2-phenylethylamine +	0
2-propylpiperidine	0
20(R)-tubotaiwine	0
20(S)-tubotaiwine	0
20-Epi-19,20-dihydro-decarbomethoxy vobasine	0
2alpha-(2'-pyrrolyl)-4alpha-methoxycarbonyl-5beta-[(2''-methyl)-heptyl]-1,3-oxazacyclohexane	0
3,4-dimethoxyphenylethylamine	0
3,9-dimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,10-diol	0
3-(4-methoxyphenyl)-3-[[2-(4-methoxyphenyl)-1-oxoethyl]amino]propanoic acid	0
3-(6-chloro-3-pyridinyl)-7-azabicyclo[2.2.1]heptane	0
3-Acetylnerbowdine	0
3-Epidemissidine	0
3-Epifortuneine	0
3-Epimacronine	0
3-Epischelhammericine	0
3-O-Acetylhamayne	0
4-(Methylthio)canthin-6-one	0
4-Hydroxycanthin-6-one	0
5-(Methylthio)canthin-6-one	0
5-Hydroxy-4-methoxy-3-methyl-2,6-canthinedione	0
5-Methoxycanthin-6-one	0
5-bromo-8-methoxy-1-methyl-beta-carboline	0
6,7-seco-Agroclavine	0
6-hydroxymanzamine A	0
7-Hydroxymitragynine	0
7-epi-cylindrospermopsin	0
8-Benzyl-9,10-dimethoxy-5,8-dihydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline	0
8-Oxoerythraline_epoxide	0
8-[(2S,4R,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-1-hydroxy-5-methoxy-3-methyl-6-[(3S)-2-oxopiperidin-3-yl]-5H-benzo[b]phenanthridine-7,12-dione	0
8-hydroxymanzamine A	0
8-oxoerythraline	0
9-(Methylthio)canthin-6-one	0
9-O-Demethyl-2alpha-hydroxyhomolycorine	0
9-O-Demethylhomolycorine	0
9-deacetylfumigaclavine C	0
9-deoxycurtisin	0
Acutumidine	0
Acutumine	0
Affinine	0
Agroclavine I	0
Akuammine	0
Albomaculine	0
Alkaloid RC	0
Allopumiliotoxin 267a	0
Aloperine	0
Alpinine	0
Amalorin	0
Amatain	0
Ambelline	0
Ammothamnine	0
Anagyrine	0
Apovincamine	0
Argentine	0
Aristolactam AII	0
Aspidospermatine	0
Atherosperminine	0
Avenanthramide 1c	0
Avenanthramide 1p	0
Avenanthramide 2	0
Avenanthramide E	0
Baloxine	0
Baptifoline	0
Berberastine	0
Berberrubine	0
Bonafousine	0
Brovincamine fumarate	0
C-Curarine	0
Calebassone	0
Candimine	0
Capaurine	0
Caracurine V	0
Caribine	0
Caseadine	0
Catharanthine hcl	0
Catharanthine hemitartrate	0
Catharine	0
Caulophylline	0
Cavinine	0
Cevadine	0
Chanoclavine II	0
Cocculolidine	0
Coccutrine	0
Colchicoside	0
Coptisine chloride	0
Coreximine	0
Corynantheidine	0
Costaclavine	0
Crinamidine	0
Crinamine	0
Crinine	0
Cularicine	0
Cularidine	0
Cularimine	0
Cularine	0
Curtisin	0
Cycloclavine	0
D-Tetrahydropalmatine	0
Deacetylcolchicine	0
Decorticasine	0
Dehydrocorydaline	0
Dehydrocorydalmine	0
Dehydrocorytenchine	0
Delavine	0
Demissidine	0
Desmethylemetine	0
Didehydrostemofoline	0
Dihydrocorynantheine	0
Dihydrolycorine	0
Dihydrosetoclavine	0
Dimethamine	0
Dubiusine	0
Duguetine	0
Eburnamenin-14(15H)-one	0
Eburnamine	0
Eburnamonine	0
Elymoclavine	0
Epoxyagroclavine I	0
Erysonine	0
Erysothiopine	0
Erysotrine	0
Erythratidine	0
Erythratine	0
Erythrina alkaloid +	0
Fawcettidine	0
Floramultine	0
Fumigaclavine D	0
Fumigaclavine E	0
Fumigaclavine F	0
Fumigaclavine G	0
Fumigaclavine H	0
Gabunamine	0
Germerine	0
Germine	0
Glaudine	0
Glaziovine	0
Haemanthamine	0
Haemanthidine	0
Hamayne	0
Harringtonine	0
Hirsuteine	0
Homoormosanine	0
Imperialine	0
Isococculidine	0
Isomatrine	0
Isorheagenine	0
Jamine	0
Jatrorrhizine	0
Kreysigine	0
L-proline betaine	0
LSM-1309	0
LSM-1372	0
LSM-1597	0
LSM-16753	0
LSM-18556	0
LSM-1944	0
LSM-22634	0
LSM-24185	0
LSM-4236	0
LSM-4502	0
LSM-5249	0
LSM-6354	0
LSM-6387	0
LSM-6464	0
LSM-6667	0
Lambertine	0
Lycoflexine	0
Lycorenine	0
Matrine	0
Mecambrine	0
Methyl (15R,17S,18S)-17-ethyl-7-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraene-1-carboxylate	0
Methyl (1R,11S,17S)-12-ethylidene-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6,9-tetraene-10-carboxylate	0
Methyl (1R,12S,20R)-12-ethyl-14-oxa-8,17-diazahexacyclo[10.7.1.01,9.02,7.013,15.017,20]icosa-2,4,6,9-tetraene-10-carboxylate	0
Methyl (1R,9S,11S,14E,15S,17S)-19-(acetyloxymethyl)-14-ethylidene-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate	0
Methyl (1S,10R,12R,19S)-12-ethyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,13-tetraene-10-carboxylate	0
Methyl (1S,15E)-15-ethylidene-12-oxo-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate	0
Methyl (Z)-2-[(3E,12bS)-3-ethylidene-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-hydroxyprop-2-enoate	0
Methyl 12-ethyl-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,13-tetraene-10-carboxylate	0
Methyl 17-(1-hydroxyethyl)-7-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraene-1-carboxylate	0
Methyl 2-(3-ethenyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl)-3-methoxyprop-2-enoate	0
Methyl 2-(3-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl)-3-methoxyprop-2-enoate	0
Methyl 2-(3-ethyl-7a-hydroxy-8-methoxy-2,3,4,6,7,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl)-3-methoxyprop-2-enoate	0
N(4)-demethyl-12-methoxyalstogustine	0
N-(lysergyl-isoleucyl)-cyclo(phenylalanyl-prolyl)	0
N-Acetylcytisine	0
N-Acetylloline	0
N-Formyldemecolcine	0
N-Formylnorloline	0
N-Methyl-14-O-demethylepiporphyroxine	0
N-Methylcanadium (iodide)	0
N-Methylloline	0
N-[2-(3,4-diethoxyphenyl)ethyl]-4-phenoxybenzamide	0
N-acetylnorloline	0
N-formylloline	0
N-methylcheilanthifoline	0
N-methylnicotinate	0
N-methylphenylethanolamine	0
Nigerrimin B	0
Nobilisitine A	0
O-Methyllycorenine	0
Oxysophocarpine	0
Paliclavine	0
Panamine	0
Paspaclavine	0
Peimisine	0
Phellodendrine	0
Piperolactam A	0
Piperolactam C	0
Piperolactam D	0
Piptanthine	0
Pretazettine	0
Promucosine	0
Protoveratrine A	0
Protoveratrine B	0
Protoverine	0
Pseudocolumbamine	0
Pseudopalmatine	0
Psychotrin	0
Pumiliotoxin 251D	0
Pumiliotoxin A	0
Pyroclavine	0
Rhoeadine	0
Rhombifoline	0
Roquefortine A	0
Roxburghine B	0
Scholaricine	0
Serratanidine	0
Serratine	0
Sinactine	0
Sipeimine	0
Sophocarpine	0
Sophoranol	0
Spinosine	0
Tabernamine	0
Tabernanthine	0
Templetine	0
Thermospine	0
Tinctorine	0
Toxiferine I	0
Verticine	0
Vinpocetine	0
Worenine	0
Xylopinine	0
Zephyranthine	0
Zhebeinine	0
Zygadenine	0
[(6Ar,9R,10S,10aR)-7,9-dimethyl-5-(2-methylbut-3-en-2-yl)-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinolin-10-yl] acetate	0
acetylcaranine	0
acremolin B	0
acronycine	0
ageladine A	1
alamarine	0
alkaloid antibiotic +	0
alkaloid ester +	0
angustilobine B, (rac)-	0
annomontine	0
ascidiathiazone A	0
ascidiathiazone B	0
aspernidine A	0
aspernigrin A +	0
asperparaline A	0
batzelladine A	0
batzelladine B	0
benzazepine alkaloid +	0
benzodiazepine alkaloid	0
beta,beta-ergoannam	0
beta-ergokryptam	0
beta-saxitoxinol(2+)	0
betalain +	0
biindole alkaloid +	0
bisindole alkaloid +	0
brovincamine	0
carbazole alkaloid +	0
carpaine	0
caulophine	0
ceratamine A	0
ceratamine B	0
cheilanthifoline	0
circumdatin H	0
colchicine +	1
coptisine	0
crambescidin 401	0
crambescidin 800	0
crambescidin 826	0
croomine	0
cryptopleurine	0
cylindrospermopsin	4
cystodytin D +	0
cystodytin E +	0
cystodytin F	0
cystodytin G	0
cytisine	0
cytochalasan alkaloid +	0
cytochalasin D	0
decahydroquinoline alkaloid +	0
decarbamoylsaxitoxin	0
deoxycylindrospermopsin	0
ent-6alpha-Hydroxybuphanisine	0
ent-6beta-Hydroxybuphanisine	0
epibatidine	0
ergoline alkaloid +	1
feruloylagmatine +	0
ficellomycin	0
glycoalkaloid +	0
gravacridonediol	0
harmala alkaloid +	0
hederacine A	0
hederacine B	0
herquline A	0
herquline B	0
herquline C	0
indirubin-3'-monoxime	0
indole alkaloid +	40
indolizidine alkaloid +	0
isoquinoline alkaloid +	1
karakoline	0
lamellarin alpha 20-hydrogen sulfate	0
leuconoxine	0
lycojapodine A	0
lycoperine A	0
lymphostin	0
manzamine A +	0
massadine	0
methyl (1S,12S,13E)-13-ethylidene-18-(hydroxymethyl)-4-methoxy-8,15-diazapentacyclo[10.5.1.01,9.02,7.010,15]octadeca-2(7),3,5,8-tetraene-18-carboxylate	0
monoamine alkaloid +	0
muscimol	0
neosaxitoxin	0
neotuberostemonine	0
nigerazine A	0
nigerazine B	0
nigragillin	0
nitensidine E	0
nostocarboline	0
oriciacridone C	0
oriciacridone F	0
oxyprotostemonine	0
paralytic shellfish toxin +	0
penipanoid B	0
phenanthrene alkaloid +	0
phenethylamine alkaloid +	0
phyllospadine	0
pipercallosidine	0
pipercallosine	0
piperidine alkaloid +	1
piperlactam S	0
protostemonine	0
pseudopelletierine	0
purine alkaloid +	1
pyridine alkaloid +	26
pyrrolidine alkaloid +	20
pyrrolizidine alkaloid +	2
pyrrolizine alkaloid +	0
pyrrolnitrin	0
quinazoline alkaloid +	0
quinoline alkaloid +	1
quinolizidine alkaloid +	0
rohitukine	0
ryanodine	2
sampangine	0
saxitoxin +	0
solanid-5-en-3-ol +	0
spermidine alkaloid +	0
spirosolane +	0
stemofoline	0
steroid alkaloid +	0
syncarpamide	0
terpene alkaloid +	0
tetrahydrocolumbamine	0
tetramethylpyrazine	0
thalictricavine	0
tropane alkaloid +	1
tuberostemonine	0
tuberostemonine N	0
undecylprodigiosin	0
veracevine	0
vinervine	0
xestospongin C	0
zarzissine	0

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