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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:alkaline earth metal atom
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Accession:CHEBI:22313 term browser browse the term
Synonyms:related_synonym: Erdalkalimetall;   Erdalkalimetalle;   alkaline-earth metal;   alkaline-earth metals;   metal alcalino-terreux;   metal alcalinoterreo;   metales alcalinoterreos;   metaux alcalino-terreux



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barium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions ISO [barium chloride results in increased abundance of Barium] which results in decreased activity of ACHE protein CTD PMID:31407482 NCBI chr 5:137,288,247...137,294,466
Ensembl chr 5:137,287,519...137,294,466
JBrowse link
G Alb albumin multiple interactions
increases secretion
ISO Plant Extracts inhibits the reaction [barium chloride results in increased secretion of ALB protein] CTD PMID:26732703 NCBI chr 5:90,460,870...90,476,602
Ensembl chr 5:90,460,897...90,476,602
JBrowse link
G Cat catalase multiple interactions
decreases activity
ISO [barium chloride results in increased abundance of Barium] which results in decreased activity of CAT protein; Plant Extracts inhibits the reaction [barium chloride results in decreased activity of CAT protein] CTD PMID:26732703 PMID:31407482 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
ISO barium chloride results in increased expression of IL1B mRNA
Plant Extracts inhibits the reaction [barium chloride results in increased expression of IL1B mRNA]
CTD PMID:26732703 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO barium chloride results in increased expression of IL6 mRNA
[barium chloride results in increased abundance of Barium] which results in increased expression of IL6 protein; Plant Extracts inhibits the reaction [barium chloride results in increased expression of IL6 mRNA]
CTD PMID:26732703 PMID:31407482 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Kcne1 potassium voltage-gated channel, Isk-related subfamily, member 1 multiple interactions ISO barium chloride results in decreased activity of [KCNQ1 protein binds to KCNE1 protein] CTD PMID:16909339 NCBI chr16:92,346,001...92,359,468
Ensembl chr16:92,345,982...92,359,468
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 multiple interactions ISO barium chloride inhibits the reaction [KCNJ2 protein results in increased transport of Potassium] CTD PMID:11087224 NCBI chr11:111,066,164...111,076,825
Ensembl chr11:111,066,164...111,076,821
JBrowse link
G Kcnk3 potassium channel, subfamily K, member 3 decreases activity ISO barium chloride results in decreased activity of KCNK3 protein CTD PMID:16020457 NCBI chr 5:30,588,170...30,625,270
Ensembl chr 5:30,588,170...30,625,271
JBrowse link
G Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 multiple interactions ISO barium chloride results in decreased activity of [KCNQ1 protein binds to KCNE1 protein] CTD PMID:16909339 NCBI chr 7:143,106,877...143,427,050
Ensembl chr 7:143,106,362...143,427,042
JBrowse link
G Mt1 metallothionein 1 increases expression
multiple interactions
ISO barium chloride results in increased expression of MT1 mRNA
Plant Extracts inhibits the reaction [barium chloride results in increased expression of MT1 mRNA]
CTD PMID:26732703 NCBI chr 8:94,178,883...94,180,327
Ensembl chr 8:94,179,082...94,180,327
JBrowse link
G Mt2 metallothionein 2 increases expression
multiple interactions
ISO barium chloride results in increased expression of MT2A mRNA
Plant Extracts inhibits the reaction [barium chloride results in increased expression of MT2A mRNA]
CTD PMID:26732703 NCBI chr 8:94,172,618...94,173,567
Ensembl chr 8:94,172,664...94,173,568
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 increases secretion ISO barium chloride results in increased secretion of SERPINE1 protein CTD PMID:21596853 NCBI chr 5:137,061,504...137,072,272
Ensembl chr 5:137,061,504...137,072,268
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial decreases expression
multiple interactions
ISO barium chloride results in decreased expression of SOD2 mRNA
Plant Extracts inhibits the reaction [barium chloride results in decreased expression of SOD2 mRNA]
CTD PMID:26732703 NCBI chr17:13,007,839...13,018,119
Ensembl chr17:13,006,846...13,040,063
JBrowse link
G Stx1a syntaxin 1A (brain) affects localization
multiple interactions
ISO barium chloride affects the localization of STX1A protein
Propofol inhibits the reaction [barium chloride affects the localization of STX1A protein]; STX1A protein modified form inhibits the reaction [Propofol inhibits the reaction [barium chloride affects the localization of STX1A protein]]
CTD PMID:29320738 NCBI chr 5:135,023,482...135,051,100
Ensembl chr 5:135,023,482...135,051,100
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO Plant Extracts inhibits the reaction [barium chloride results in increased expression of TNF mRNA] CTD PMID:26732703 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions EXP [barium chloride results in increased abundance of Barium] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:140,539,528...140,600,522
Ensembl chr  X:140,539,528...140,600,659
JBrowse link
barium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmbs hydroxymethylbilane synthase decreases activity ISO Barium ion decreases activity of purified Hmbs protein RGD PMID:6732900 RGD:25394584 NCBI chr 9:44,336,348...44,344,228
Ensembl chr 9:44,336,339...44,344,228
JBrowse link
barium sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin increases expression ISO Barium Sulfate results in increased expression of ALB mRNA CTD PMID:29463257 NCBI chr 5:90,460,870...90,476,602
Ensembl chr 5:90,460,897...90,476,602
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO Barium Sulfate results in increased expression of BIRC5 mRNA CTD PMID:29463257 NCBI chr11:117,849,237...117,855,743
Ensembl chr11:117,849,251...117,855,743
JBrowse link
G Ccl11 chemokine (C-C motif) ligand 11 increases expression ISO Barium Sulfate results in increased expression of CCL11 mRNA CTD PMID:29463257 NCBI chr11:82,057,832...82,062,955
Ensembl chr11:82,057,823...82,062,955
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 increases expression
increases secretion
ISO Barium Sulfate results in increased expression of CCL2 mRNA
Barium Sulfate results in increased secretion of CCL2 protein
CTD PMID:29463257 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Ccl20 chemokine (C-C motif) ligand 20 affects expression ISO Barium Sulfate affects the expression of CCL20 mRNA CTD PMID:29463257 NCBI chr 1:83,116,766...83,119,167
Ensembl chr 1:83,116,766...83,119,167
JBrowse link
G Ccl22 chemokine (C-C motif) ligand 22 increases expression ISO Barium Sulfate results in increased expression of CCL22 mRNA CTD PMID:29463257 NCBI chr 8:94,745,684...94,751,388
Ensembl chr 8:94,745,590...94,751,699
JBrowse link
G Ccl24 chemokine (C-C motif) ligand 24 increases expression ISO Barium Sulfate results in increased expression of CCL24 mRNA CTD PMID:29463257 NCBI chr 5:135,569,935...135,573,123
Ensembl chr 5:135,569,937...135,573,049
JBrowse link
G Ccl4 chemokine (C-C motif) ligand 4 decreases expression ISO Barium Sulfate results in decreased expression of CCL4 mRNA CTD PMID:29463257 NCBI chr11:83,648,624...83,664,683
Ensembl chr11:83,662,584...83,664,683
JBrowse link
G Ccl7 chemokine (C-C motif) ligand 7 increases expression ISO Barium Sulfate results in increased expression of CCL7 mRNA CTD PMID:29463257 NCBI chr11:82,045,712...82,047,525
Ensembl chr11:82,045,712...82,047,525
JBrowse link
G Ccr2 chemokine (C-C motif) receptor 2 increases expression ISO Barium Sulfate results in increased expression of CCR2 mRNA CTD PMID:29463257 NCBI chr 9:124,101,918...124,109,140
Ensembl chr 9:124,101,950...124,113,557
JBrowse link
G Cd40lg CD40 ligand decreases expression ISO Barium Sulfate results in decreased expression of CD40LG mRNA CTD PMID:29463257 NCBI chr  X:57,212,143...57,224,042
Ensembl chr  X:57,212,143...57,224,042
JBrowse link
G Cxcl9 chemokine (C-X-C motif) ligand 9 increases expression ISO Barium Sulfate results in increased expression of CXCL9 mRNA CTD PMID:29463257 NCBI chr 5:92,321,331...92,328,079
Ensembl chr 5:92,321,347...92,328,079
JBrowse link
G Cxcr3 chemokine (C-X-C motif) receptor 3 increases expression ISO Barium Sulfate results in increased expression of CXCR3 mRNA CTD PMID:29463257 NCBI chr  X:101,731,535...101,734,147
Ensembl chr  X:101,731,535...101,734,269
JBrowse link
G Cyp4a12b cytochrome P450, family 4, subfamily a, polypeptide 12B increases expression ISO Barium Sulfate results in increased expression of CYP4A1 mRNA CTD PMID:11124224 NCBI chr 4:115,411,624...115,439,034
Ensembl chr 4:115,411,624...115,439,034
JBrowse link
G Cyp4f14 cytochrome P450, family 4, subfamily f, polypeptide 14 increases expression ISO Barium Sulfate results in increased expression of CYP4F1 mRNA CTD PMID:14644421 NCBI chr17:32,903,357...32,917,376
Ensembl chr17:32,905,070...32,917,342
JBrowse link
G Cyp4f16 cytochrome P450, family 4, subfamily f, polypeptide 16 increases expression ISO Barium Sulfate results in increased expression of CYP4F6 mRNA CTD PMID:14644421 NCBI chr17:32,536,545...32,551,798
Ensembl chr17:32,536,558...32,551,798
JBrowse link
G Exo1 exonuclease 1 affects expression ISO Barium Sulfate affects the expression of EXO1 mRNA CTD PMID:29463257 NCBI chr 1:175,880,768...175,911,396
Ensembl chr 1:175,880,581...175,913,489
JBrowse link
G Fabp4 fatty acid binding protein 4, adipocyte decreases expression ISO Barium Sulfate results in decreased expression of FABP4 mRNA CTD PMID:29463257 NCBI chr 3:10,204,342...10,208,616
Ensembl chr 3:10,204,088...10,208,576
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 decreases expression ISO Barium Sulfate results in decreased expression of HBA1 mRNA CTD PMID:29463257 NCBI chr11:32,296,492...32,297,310
Ensembl chr11:32,296,489...32,297,298
JBrowse link
G Il2rb interleukin 2 receptor, beta chain decreases expression ISO Barium Sulfate results in decreased expression of IL2RB mRNA CTD PMID:29463257 NCBI chr15:78,479,256...78,511,621
Ensembl chr15:78,479,256...78,495,271
JBrowse link
G Il6 interleukin 6 increases expression ISO Barium Sulfate results in increased expression of IL6 protein CTD PMID:11403239 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Krt1 keratin 1 increases expression ISO Barium Sulfate results in increased expression of KRT1 mRNA CTD PMID:29463257 NCBI chr15:101,845,426...101,850,786
Ensembl chr15:101,845,426...101,850,794
JBrowse link
G Lig4 ligase IV, DNA, ATP-dependent increases expression ISO Barium Sulfate results in increased expression of LIG4 mRNA CTD PMID:29463257 NCBI chr 8:9,970,020...9,977,680
Ensembl chr 8:9,969,049...9,977,686
JBrowse link
G Lpo lactoperoxidase increases expression ISO Barium Sulfate results in increased expression of LPO mRNA; Barium Sulfate results in increased expression of LPO protein CTD PMID:29463257 NCBI chr11:87,806,428...87,826,114
Ensembl chr11:87,806,428...87,828,289
JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression ISO Barium Sulfate results in increased expression of MMP12 mRNA; Barium Sulfate results in increased expression of MMP12 protein CTD PMID:29463257 NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499
JBrowse link
G Mutyh mutY DNA glycosylase increases expression ISO Barium Sulfate results in increased expression of MUTYH mRNA CTD PMID:29463257 NCBI chr 4:116,807,636...116,819,439
Ensembl chr 4:116,807,723...116,819,440
JBrowse link
G Ngb neuroglobin decreases expression ISO Barium Sulfate results in decreased expression of NGB mRNA CTD PMID:29463257 NCBI chr12:87,097,531...87,102,539
Ensembl chr12:87,097,531...87,102,539
JBrowse link
G Noxo1 NADPH oxidase organizer 1 increases expression ISO Barium Sulfate results in increased expression of NOXO1 mRNA CTD PMID:29463257 NCBI chr17:24,696,234...24,700,530
Ensembl chr17:24,696,234...24,700,529
JBrowse link
G Opcml opioid binding protein/cell adhesion molecule-like increases expression ISO Barium Sulfate results in increased expression of OPCML mRNA CTD PMID:29463257 NCBI chr 9:27,790,716...28,925,410
Ensembl chr 9:27,790,775...28,925,410
JBrowse link
G Pf4 platelet factor 4 increases expression ISO Barium Sulfate results in increased expression of PF4 mRNA CTD PMID:29463257 NCBI chr 5:90,772,435...90,773,383
Ensembl chr 5:90,772,435...90,773,383
JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 affects expression ISO Barium Sulfate affects the expression of SCD1 mRNA CTD PMID:29463257 NCBI chr19:44,394,450...44,407,709
Ensembl chr19:44,394,455...44,407,879
JBrowse link
G Tcf21 transcription factor 21 decreases expression ISO Barium Sulfate results in decreased expression of TCF21 mRNA CTD PMID:29463257 NCBI chr10:22,817,263...22,820,143
Ensembl chr10:22,817,281...22,820,174
JBrowse link
G Thbs2 thrombospondin 2 increases expression ISO Barium Sulfate results in increased expression of THBS2 mRNA CTD PMID:29463257 NCBI chr17:14,665,500...14,694,262
Ensembl chr17:14,665,500...14,694,235
JBrowse link
G Top2a topoisomerase (DNA) II alpha increases expression ISO Barium Sulfate results in increased expression of TOP2A mRNA CTD PMID:29463257 NCBI chr11:98,992,947...99,024,199
Ensembl chr11:98,992,943...99,024,189
JBrowse link
G Txnip thioredoxin interacting protein decreases expression ISO Barium Sulfate results in decreased expression of TXNIP mRNA CTD PMID:29463257 NCBI chr 3:96,557,957...96,561,857
Ensembl chr 3:96,557,957...96,561,883
JBrowse link
G Xrcc2 X-ray repair complementing defective repair in Chinese hamster cells 2 increases expression ISO Barium Sulfate results in increased expression of XRCC2 mRNA CTD PMID:29463257 NCBI chr 5:25,689,814...25,705,797
Ensembl chr 5:25,689,812...25,705,825
JBrowse link
barium(0) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions ISO [barium chloride results in increased abundance of Barium] which results in decreased activity of ACHE protein CTD PMID:31407482 NCBI chr 5:137,288,247...137,294,466
Ensembl chr 5:137,287,519...137,294,466
JBrowse link
G Adra1a adrenergic receptor, alpha 1a multiple interactions EXP ADRA1A protein promotes the reaction [TRPC6 protein results in increased transport of Barium] CTD PMID:11179201 NCBI chr14:66,635,251...66,771,240
Ensembl chr14:66,635,251...66,771,168
JBrowse link
G Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit increases transport ISO CACNA1A protein results in increased transport of Barium CTD PMID:11313431 NCBI chr 8:84,338,631...84,640,251
Ensembl chr 8:84,338,639...84,640,246
JBrowse link
G Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit affects transport
increases transport
multiple interactions
ISO CACNA1B gene polymorphism affects the transport of Barium
CACNA1B protein results in increased transport of Barium
[GNB1 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB1 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB1 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB5 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; Cadmium Chloride inhibits the reaction [CACNA1B protein results in increased transport of Barium]
CTD PMID:11007869 PMID:11756491 PMID:14559144 NCBI chr 2:24,603,860...24,763,200
Ensembl chr 2:24,603,887...24,763,152
JBrowse link
G Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit increases transport ISO CACNA1C protein results in increased transport of Barium CTD PMID:17569661 NCBI chr 6:118,587,240...119,197,384
Ensembl chr 6:118,587,240...119,196,890
Ensembl chr 6:118,587,240...119,196,890
JBrowse link
G Cacna1d calcium channel, voltage-dependent, L type, alpha 1D subunit affects transport
multiple interactions
increases transport
EXP
ISO
CACNA1D protein affects the transport of Barium
CACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Barium]
CACNA1D protein results in increased transport of Barium
CTD PMID:15357422 PMID:17567805 PMID:27798183 NCBI chr14:30,039,941...30,491,156
Ensembl chr14:30,039,939...30,491,455
JBrowse link
G Cacna1e calcium channel, voltage-dependent, R type, alpha 1E subunit increases transport
multiple interactions
affects transport
ISO
EXP
CACNA1E mRNA alternative form results in increased transport of Barium; CACNA1E protein results in increased transport of Barium
1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid affects the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; 4-O-methyl-12-O-tetradecanoylphorbol 13-acetate affects the reaction [CACNA1E protein results in increased transport of Barium]; Atropine inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; Calcium inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; Heparin affects the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; Isradipine inhibits the reaction [CACNA1E protein results in increased transport of Barium]; Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]; Nickel inhibits the reaction [CACNA1E protein results in increased transport of Barium]; omega-conotoxin-MVIIC promotes the reaction [Isradipine inhibits the reaction [CACNA1E protein results in increased transport of Barium]]; Ro 31-8425 inhibits the reaction [4-O-methyl-12-O-tetradecanoylphorbol 13-acetate affects the reaction [CACNA1E protein results in increased transport of Barium]]; Ro 31-8425 inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; SNX 482 inhibits the reaction [CACNA1E protein results in increased transport of Barium]
SNX 482 inhibits the reaction [CACNA1E mRNA alternative form results in increased transport of Barium]
CACNA1E protein affects the transport of Barium
CTD PMID:10627594 PMID:10669483 PMID:11102459 PMID:11179973 PMID:12663092 More... NCBI chr 1:154,390,806...154,884,785
Ensembl chr 1:154,390,731...154,884,501
JBrowse link
G Cacna1f calcium channel, voltage-dependent, alpha 1F subunit multiple interactions
increases transport
EXP 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester promotes the reaction [CACNA1F protein results in increased transport of Barium]; Diltiazem inhibits the reaction [CACNA1F protein results in increased transport of Barium]; Isradipine inhibits the reaction [CACNA1F protein results in increased transport of Barium]; Verapamil inhibits the reaction [CACNA1F protein results in increased transport of Barium] CTD PMID:14744918 NCBI chr  X:7,607,103...7,635,196
Ensembl chr  X:7,607,083...7,635,196
JBrowse link
G Cacna1g calcium channel, voltage-dependent, T type, alpha 1G subunit increases transport
multiple interactions
ISO CACNA1G mRNA alternative form results in increased transport of Barium; CACNA1G protein results in increased transport of Barium
Cerium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Erbium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Gadolinium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Holmium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Lanthanum inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Neodymium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Scandium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Ytterbium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Yttrium inhibits the reaction [CACNA1G protein results in increased transport of Barium]
CTD PMID:11179973 PMID:12163980 NCBI chr11:94,408,391...94,474,400
Ensembl chr11:94,408,391...94,474,198
JBrowse link
G Cacna1h calcium channel, voltage-dependent, T type, alpha 1H subunit increases transport ISO CACNA1H mRNA alternative form results in increased transport of Barium CTD PMID:11179973 NCBI chr17:25,374,285...25,436,334
Ensembl chr17:25,374,285...25,433,783
JBrowse link
G Cacna1i calcium channel, voltage-dependent, alpha 1I subunit increases transport ISO CACNA1I mRNA alternative form results in increased transport of Barium CTD PMID:11179973 NCBI chr15:80,287,238...80,398,292
Ensembl chr15:80,287,238...80,398,279
JBrowse link
G Cacna2d1 calcium channel, voltage-dependent, alpha2/delta subunit 1 affects transport
increases transport
ISO CACNA2D1 protein affects the transport of Barium
CACNA2D1 protein results in increased transport of Barium
CTD PMID:11313431 PMID:15245474 PMID:15474003 NCBI chr 5:15,934,264...16,374,511
Ensembl chr 5:15,934,691...16,374,511
JBrowse link
G Cacna2d2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 multiple interactions EXP CACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Barium] CTD PMID:27798183 NCBI chr 9:107,399,733...107,529,346
Ensembl chr 9:107,399,612...107,529,343
JBrowse link
G Cacnb3 calcium channel, voltage-dependent, beta 3 subunit affects transport ISO CACNB3 protein affects the transport of Barium CTD PMID:15245474 NCBI chr15:98,628,436...98,644,536
Ensembl chr15:98,630,840...98,644,529
JBrowse link
G Cacnb4 calcium channel, voltage-dependent, beta 4 subunit affects transport ISO CACNB4 protein affects the transport of Barium CTD PMID:11313431 PMID:15245474 NCBI chr 2:52,428,320...52,676,609
Ensembl chr 2:52,428,320...52,676,831
JBrowse link
G Cacng2 calcium channel, voltage-dependent, gamma subunit 2 affects transport ISO CACNG2 protein affects the transport of Barium CTD PMID:11313431 NCBI chr15:77,991,919...78,120,220
Ensembl chr15:77,991,748...78,120,028
JBrowse link
G Cacng3 calcium channel, voltage-dependent, gamma subunit 3 affects transport ISO CACNG3 protein affects the transport of Barium CTD PMID:11313431 NCBI chr 7:122,671,744...122,769,393
Ensembl chr 7:122,670,492...122,769,393
JBrowse link
G Cat catalase multiple interactions ISO [barium chloride results in increased abundance of Barium] which results in decreased activity of CAT protein CTD PMID:31407482 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Chrna2 cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) multiple interactions ISO 1-Butanol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 1-Propanol promotes the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 2-butanol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 2-Propanol promotes the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; [CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium; Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]; crotonyl alcohol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; isobutyl alcohol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; n-pentanol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; tert-Butyl Alcohol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]] CTD PMID:11821649 NCBI chr14:66,133,236...66,152,948
Ensembl chr14:66,135,039...66,152,948
JBrowse link
G Chrna4 cholinergic receptor, nicotinic, alpha polypeptide 4 multiple interactions ISO [CHRNA4 protein co-treated with CHRNB2 protein] affects the reaction [Barium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein mutant form co-treated with CHRNB2 protein] inhibits the reaction [Barium results in increased susceptibility to Acetylcholine] CTD PMID:12754307 NCBI chr 2:181,022,311...181,043,579
Ensembl chr 2:181,018,380...181,043,546
JBrowse link
G Chrnb2 cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) multiple interactions ISO [CHRNA4 protein co-treated with CHRNB2 protein] affects the reaction [Barium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein mutant form co-treated with CHRNB2 protein] inhibits the reaction [Barium results in increased susceptibility to Acetylcholine] CTD PMID:12754307 NCBI chr 3:89,753,448...89,764,632
Ensembl chr 3:89,746,195...89,764,632
JBrowse link
G Chrnb4 cholinergic receptor, nicotinic, beta polypeptide 4 multiple interactions ISO 1-Butanol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 1-Propanol promotes the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 2-butanol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 2-Propanol promotes the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; [CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium; Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]; crotonyl alcohol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; isobutyl alcohol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; n-pentanol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; tert-Butyl Alcohol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]] CTD PMID:11821649 NCBI chr 9:55,028,154...55,048,953
Ensembl chr 9:55,028,154...55,048,779
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
decreases transport
ISO 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester inhibits the reaction [DRD2 protein results in decreased transport of Barium]; [DRD2 protein affects the abundance of Calcium] which results in decreased transport of Barium; [DRD2 protein results in increased activity of PLCB1 protein] which results in decreased transport of Barium; DRD2 protein affects the reaction [N-n-propylnorapomorphine analog results in decreased transport of Barium]; DRD2 protein affects the reaction [Quinpirole results in decreased transport of Barium]; Nifedipine inhibits the reaction [DRD2 protein affects the reaction [Quinpirole results in decreased transport of Barium]] CTD PMID:11124974 NCBI chr 9:49,340,360...49,408,177
Ensembl chr 9:49,340,627...49,408,177
JBrowse link
G F2 coagulation factor II increases uptake
multiple interactions
ISO F2 protein results in increased uptake of Barium
Nickel inhibits the reaction [F2 protein results in increased uptake of Barium]
CTD PMID:2125206 NCBI chr 2:91,612,397...91,636,457
Ensembl chr 2:91,625,320...91,636,414
JBrowse link
G F2rl1 coagulation factor II (thrombin) receptor-like 1 multiple interactions ISO Barium inhibits the reaction [F2RL1 protein results in increased transport of Chlorides]; F2RL1 protein affects the reaction [1-oleoyl-2-acetoyl-sn-glycerol results in increased transport of Barium] CTD PMID:11804840 PMID:16123040 NCBI chr13:95,511,718...95,525,240
Ensembl chr13:95,511,732...95,525,227
JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 decreases activity ISO Barium results in decreased activity of FXYD2 protein CTD PMID:11533133 NCBI chr 9:45,399,709...45,410,278
Ensembl chr 9:45,399,669...45,410,278
JBrowse link
G Gnb1 guanine nucleotide binding protein (G protein), beta 1 multiple interactions ISO [GNB1 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB1 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB1 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr 4:155,491,300...155,559,269
Ensembl chr 4:155,491,361...155,559,269
JBrowse link
G Gnb2 guanine nucleotide binding protein (G protein), beta 2 multiple interactions ISO [GNB2 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr 5:137,528,127...137,533,449
Ensembl chr 5:137,528,127...137,533,510
JBrowse link
G Gnb3 guanine nucleotide binding protein (G protein), beta 3 multiple interactions ISO [GNB3 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr 6:124,834,240...124,840,275
Ensembl chr 6:124,834,240...124,840,275
JBrowse link
G Gnb4 guanine nucleotide binding protein (G protein), beta 4 multiple interactions ISO [GNB4 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr 3:32,578,587...32,616,673
Ensembl chr 3:32,580,332...32,616,585
JBrowse link
G Gnb5 guanine nucleotide binding protein (G protein), beta 5 multiple interactions ISO [GNB5 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr 9:75,306,288...75,345,923
Ensembl chr 9:75,306,288...75,345,876
JBrowse link
G Gng2 guanine nucleotide binding protein (G protein), gamma 2 multiple interactions ISO [GNB1 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB5 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr14:19,872,558...19,977,825
Ensembl chr14:19,872,559...19,977,627
JBrowse link
G Gng3 guanine nucleotide binding protein (G protein), gamma 3 multiple interactions ISO [GNB1 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr19:8,836,929...8,839,246
Ensembl chr19:8,836,933...8,839,194
JBrowse link
G Gngt1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 multiple interactions ISO [GNB1 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr 6:3,989,082...3,997,436
Ensembl chr 6:3,993,792...3,997,436
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [barium chloride results in increased abundance of Barium] which results in increased expression of IL6 protein CTD PMID:31407482 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Kcna10 potassium voltage-gated channel, shaker-related subfamily, member 10 multiple interactions ISO Barium inhibits the reaction [KCNA10 protein results in increased transport of Potassium] CTD PMID:10836990 NCBI chr 3:107,183,143...107,195,721
Ensembl chr 3:107,183,056...107,195,721
JBrowse link
G Kcne1 potassium voltage-gated channel, Isk-related subfamily, member 1 multiple interactions ISO Barium results in decreased activity of [KCNQ1 protein binds to KCNE1 protein] CTD PMID:16909339 NCBI chr16:92,346,001...92,359,468
Ensembl chr16:92,345,982...92,359,468
JBrowse link
G Kcnh1 potassium voltage-gated channel, subfamily H (eag-related), member 1 decreases activity ISO Barium results in decreased activity of KCNH1 protein CTD PMID:10896755 NCBI chr 1:192,189,144...192,510,159
Ensembl chr 1:192,190,774...192,510,159
JBrowse link
G Kcnh3 potassium voltage-gated channel, subfamily H (eag-related), member 3 multiple interactions ISO Barium binds to and results in decreased activity of KCNH3 protein CTD PMID:12193184 NCBI chr15:99,224,517...99,242,818
Ensembl chr15:99,224,861...99,242,817
JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 decreases activity ISO Barium results in decreased activity of KCNJ10 protein CTD PMID:16331678 PMID:17978865 NCBI chr 1:172,341,210...172,374,085
Ensembl chr 1:172,341,210...172,374,085
JBrowse link
G Kcnj12 potassium inwardly-rectifying channel, subfamily J, member 12 multiple interactions ISO Barium inhibits the reaction [KCNJ12 protein results in increased transport of Potassium] CTD PMID:15958527 NCBI chr11:61,022,564...61,073,269
Ensembl chr11:61,022,564...61,071,131
JBrowse link
G Kcnj14 potassium inwardly-rectifying channel, subfamily J, member 14 multiple interactions ISO Barium inhibits the reaction [KCNJ14 protein results in increased transport of Potassium] CTD PMID:10938328 PMID:17347781 NCBI chr 7:45,816,467...45,824,747
Ensembl chr 7:45,816,460...45,824,782
JBrowse link
G Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 decreases activity ISO Barium results in decreased activity of KCNJ15 protein CTD PMID:15328350 NCBI chr16:95,257,558...95,300,260
Ensembl chr16:95,257,558...95,300,260
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 multiple interactions
decreases activity
ISO
EXP
Barium inhibits the reaction [KCNJ2 protein results in increased transport of Potassium]
Barium results in decreased activity of KCNJ2 protein
CTD PMID:12598232 PMID:15958527 PMID:17347781 PMID:17699636 NCBI chr11:111,066,164...111,076,825
Ensembl chr11:111,066,164...111,076,821
JBrowse link
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 decreases activity
multiple interactions
ISO
EXP
Barium results in decreased activity of KCNJ4 protein
Barium inhibits the reaction [KCNJ4 protein results in increased transport of Potassium]
CTD PMID:12598232 PMID:17091215 NCBI chr15:79,480,226...79,512,511
Ensembl chr15:79,483,714...79,505,241
JBrowse link
G Kcnk1 potassium channel, subfamily K, member 1 multiple interactions EXP Barium inhibits the reaction [KCNK1 protein results in increased transport of Potassium]; Barium inhibits the reaction [KCNK1 protein results in increased transport of Sodium] CTD PMID:16847696 NCBI chr 8:125,993,655...126,030,685
Ensembl chr 8:125,995,170...126,030,685
JBrowse link
G Kcnk18 potassium channel, subfamily K, member 18 multiple interactions ISO Barium inhibits the reaction [KCNK18 protein results in increased transport of Potassium] CTD PMID:12754259 NCBI chr19:59,219,648...59,237,370
Ensembl chr19:59,219,214...59,237,374
JBrowse link
G Kcnk9 potassium channel, subfamily K, member 9 multiple interactions ISO Barium inhibits the reaction [KCNK9 protein results in increased transport of Potassium] CTD PMID:10734076 NCBI chr15:72,501,873...72,548,614
Ensembl chr15:72,501,089...72,546,340
JBrowse link
G Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 multiple interactions ISO Barium results in decreased activity of [KCNQ1 protein binds to KCNE1 protein] CTD PMID:16909339 NCBI chr 7:143,106,877...143,427,050
Ensembl chr 7:143,106,362...143,427,042
JBrowse link
G Mir30a microRNA 30a multiple interactions ISO [Air Pollutants, Occupational results in increased abundance of Barium] which results in decreased expression of MIR30A mRNA CTD PMID:27506416 NCBI chr 1:23,272,269...23,272,339
Ensembl chr 1:23,272,269...23,272,339
JBrowse link
G Mmp14 matrix metallopeptidase 14 (membrane-inserted) increases expression ISO Barium results in increased expression of MMP14 protein CTD PMID:23804419 NCBI chr14:54,431,598...54,442,456
Ensembl chr14:54,431,612...54,445,364
JBrowse link
G Npr3 natriuretic peptide receptor 3 multiple interactions ISO Barium inhibits the reaction [NPR3 protein affects the reaction [Enterotoxins affects the transport of Potassium]]; Barium inhibits the reaction [NPR3 protein affects the reaction [guanylin affects the transport of Potassium]] CTD PMID:11889121 NCBI chr15:11,839,896...11,907,837
Ensembl chr15:11,839,896...11,907,287
JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 multiple interactions ISO P2RX7 protein affects the reaction [Adenosine Triphosphate results in increased transport of Barium] CTD PMID:11003599 NCBI chr 5:122,643,927...122,692,336
Ensembl chr 5:122,643,911...122,691,432
JBrowse link
G Plcb1 phospholipase C, beta 1 multiple interactions ISO [DRD2 protein results in increased activity of PLCB1 protein] which results in decreased transport of Barium CTD PMID:11124974 NCBI chr 2:134,786,164...135,475,258
Ensembl chr 2:134,786,067...135,475,258
JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 increases phosphorylation ISO Barium results in increased phosphorylation of PTK2 protein CTD PMID:23804419 NCBI chr15:73,205,102...73,423,820
Ensembl chr15:73,205,102...73,423,280
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 multiple interactions ISO Barium inhibits the reaction [SGK1 protein results in increased transport of Potassium] CTD PMID:12590200 NCBI chr10:21,882,184...21,999,903
Ensembl chr10:21,882,184...21,999,903
JBrowse link
G Sgk2 serum/glucocorticoid regulated kinase 2 multiple interactions ISO Barium inhibits the reaction [SGK2 protein results in increased transport of Potassium] CTD PMID:12590200 NCBI chr 2:162,987,327...163,014,139
Ensembl chr 2:162,987,330...163,014,127
JBrowse link
G Sgk3 serum/glucocorticoid regulated kinase 3 multiple interactions ISO Barium inhibits the reaction [SGK3 protein results in increased transport of Potassium] CTD PMID:12590200 NCBI chr 1:9,798,130...9,902,570
Ensembl chr 1:9,798,107...9,900,845
JBrowse link
G Slc12a4 solute carrier family 12, member 4 multiple interactions EXP Barium inhibits the reaction [SLC12A4 protein results in increased transport of Potassium] CTD PMID:11703599 NCBI chr 8:105,943,590...105,966,149
Ensembl chr 8:105,943,590...105,966,097
JBrowse link
G Slc12a7 solute carrier family 12, member 7 decreases activity EXP Barium results in decreased activity of SLC12A7 protein CTD PMID:10913127 NCBI chr13:73,733,052...73,816,754
Ensembl chr13:73,733,094...73,816,754
JBrowse link
G Slc22a12 solute carrier family 22 (organic anion/cation transporter), member 12 multiple interactions EXP Barium promotes the reaction [SLC22A12 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:15284287 NCBI chr19:6,535,854...6,543,070
Ensembl chr19:6,535,845...6,543,032
JBrowse link
G Slc22a3 solute carrier family 22 (organic cation transporter), member 3 multiple interactions EXP Barium inhibits the reaction [SLC22A3 protein results in increased uptake of Tetraethylammonium] CTD PMID:10966924 NCBI chr17:12,419,972...12,507,704
Ensembl chr17:12,418,960...12,507,704
JBrowse link
G Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 affects transport EXP SLC8A1 protein affects the transport of Barium CTD PMID:17560225 NCBI chr17:81,373,105...81,738,387
Ensembl chr17:81,373,105...81,738,377
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Barium inhibits the reaction [TNF protein results in increased transport of Potassium] CTD PMID:10783394 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 multiple interactions
increases transport
ISO
EXP
1-oleoyl-2-acetylglycerol promotes the reaction [TRPC3 protein results in increased transport of Barium]
1-oleoyl-2-acetoyl-sn-glycerol affects the reaction [TRPC3 protein results in increased transport of Barium]
CTD PMID:11042129 PMID:16055711 NCBI chr 3:36,620,482...36,690,429
Ensembl chr 3:36,620,482...36,690,167
JBrowse link
G Trpc4 transient receptor potential cation channel, subfamily C, member 4 multiple interactions
increases transport
ISO TRPC4 protein affects the reaction [Carbachol results in increased transport of Barium]
TRPC4 protein results in increased transport of Barium
CTD PMID:11042129 PMID:11830588 NCBI chr 3:54,155,584...54,318,471
Ensembl chr 3:54,156,035...54,318,471
JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 multiple interactions
increases transport
affects transport
EXP 1-oleoyl-2-acetoyl-sn-glycerol affects the reaction [TRPC6 protein affects the transport of Barium]; ADRA1A protein promotes the reaction [TRPC6 protein results in increased transport of Barium] CTD PMID:11179201 PMID:16055711 NCBI chr 9:8,543,867...8,680,752
Ensembl chr 9:8,544,142...8,680,741
JBrowse link
G Trpm6 transient receptor potential cation channel, subfamily M, member 6 multiple interactions ISO TRPM6 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Barium]; TRPM6 protein affects the reaction [1-stearoyl-2-arachidonoylglycerol results in increased transport of Barium] CTD PMID:11988098 NCBI chr19:18,730,177...18,892,521
Ensembl chr19:18,749,983...18,892,511
JBrowse link
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 increases uptake ISO TRPV6 protein results in increased uptake of Barium CTD PMID:19996302 PMID:21146870 NCBI chr 6:41,620,619...41,636,405
Ensembl chr 6:41,620,624...41,636,405
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions EXP [barium chloride results in increased abundance of Barium] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:140,539,528...140,600,522
Ensembl chr  X:140,539,528...140,600,659
JBrowse link
G Urod uroporphyrinogen decarboxylase affects abundance ISO UROD protein affects the abundance of Barium CTD PMID:16325539 NCBI chr 4:116,989,965...116,994,436
Ensembl chr 4:116,989,965...116,994,413
JBrowse link
beryllium atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin dependent kinase inhibitor 2A multiple interactions ISO [Beryllium results in increased methylation of CDKN2A promoter] which results in decreased expression of CDKN2A mRNA CTD PMID:11872642 NCBI chr 4:89,274,473...89,294,619
Ensembl chr 4:89,274,471...89,294,653
JBrowse link
G Esr1 estrogen receptor 1 (alpha) increases methylation ISO Beryllium results in increased methylation of ESR1 gene CTD PMID:11872642 NCBI chr10:4,611,989...5,005,633
Ensembl chr10:4,611,593...5,005,614
JBrowse link
G Hras Harvey rat sarcoma virus oncogene increases mutagenesis ISO Beryllium results in increased mutagenesis of HRAS gene CTD PMID:7545909 NCBI chr 7:141,189,934...141,194,019
Ensembl chr 7:141,189,105...141,194,005
JBrowse link
G Il1b interleukin 1 beta increases expression
affects expression
ISO Beryllium results in increased expression of IL1B mRNA
Beryllium affects the expression of IL1B mRNA
CTD PMID:8473757 PMID:8629860 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Tnf tumor necrosis factor increases response to substance
increases secretion
increases expression
ISO TNF promoter polymorphism results in increased susceptibility to Beryllium
Beryllium results in increased secretion of TNF protein
Beryllium results in increased expression of TNF mRNA
CTD PMID:8629860 PMID:12449171 PMID:15127972 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
beryllium dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apex1 apurinic/apyrimidinic endonuclease 1 affects expression EXP beryllium chloride affects the expression of APEX1 mRNA CTD PMID:23793613 NCBI chr14:50,924,949...50,927,188
Ensembl chr14:50,924,968...50,927,139
JBrowse link
G Ogg1 8-oxoguanine DNA-glycosylase 1 affects expression EXP beryllium chloride affects the expression of OGG1 mRNA CTD PMID:23793613 NCBI chr 6:113,326,972...113,334,877
Ensembl chr 6:113,326,972...113,335,068
JBrowse link
G Trp53 transformation related protein 53 increases expression EXP beryllium chloride results in increased expression of TRP53 mRNA CTD PMID:23793613 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
beryllium difluoride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A multiple interactions ISO beryllium fluoride promotes the reaction [ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate] CTD PMID:11027628 NCBI chr 5:8,567,091...8,748,575
Ensembl chr 5:8,660,077...8,748,575
JBrowse link
G Abcc6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 multiple interactions ISO beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]; Cobalt promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]]; Magnesium Chloride promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]]; Manganese promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]]; Nickel promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]] CTD PMID:12069597 NCBI chr 7:45,974,110...46,030,491
Ensembl chr 7:45,967,555...46,030,302
JBrowse link
G Abcc8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 decreases activity ISO beryllium fluoride results in decreased activity of ABCC8 protein CTD PMID:17561960 PMID:18025464 NCBI chr 7:46,104,523...46,180,039
Ensembl chr 7:46,104,523...46,180,033
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression EXP beryllium fluoride results in increased expression of CREB1 protein CTD PMID:11867686 NCBI chr 1:64,532,794...64,604,548
Ensembl chr 1:64,532,645...64,604,548
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression EXP beryllium fluoride results in increased expression of FOS protein CTD PMID:11867686 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 increases phosphorylation EXP beryllium fluoride results in increased phosphorylation of MAP2K1 protein CTD PMID:11867686 NCBI chr 9:64,185,769...64,253,605
Ensembl chr 9:64,185,770...64,253,631
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 increases phosphorylation EXP beryllium fluoride results in increased phosphorylation of MAPK3 protein CTD PMID:11867686 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Myc myelocytomatosis oncogene increases expression EXP beryllium fluoride results in increased expression of MYC protein CTD PMID:11867686 NCBI chr15:61,985,341...61,990,361
Ensembl chr15:61,985,391...61,990,374
JBrowse link
beryllium dihydride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin dependent kinase inhibitor 2A multiple interactions ISO [Beryllium results in increased methylation of CDKN2A promoter] which results in decreased expression of CDKN2A mRNA CTD PMID:11872642 NCBI chr 4:89,274,473...89,294,619
Ensembl chr 4:89,274,471...89,294,653
JBrowse link
G Esr1 estrogen receptor 1 (alpha) increases methylation ISO Beryllium results in increased methylation of ESR1 gene CTD PMID:11872642 NCBI chr10:4,611,989...5,005,633
Ensembl chr10:4,611,593...5,005,614
JBrowse link
G Hras Harvey rat sarcoma virus oncogene increases mutagenesis ISO Beryllium results in increased mutagenesis of HRAS gene CTD PMID:7545909 NCBI chr 7:141,189,934...141,194,019
Ensembl chr 7:141,189,105...141,194,005
JBrowse link
G Il1b interleukin 1 beta increases expression
affects expression
ISO Beryllium results in increased expression of IL1B mRNA
Beryllium affects the expression of IL1B mRNA
CTD PMID:8473757 PMID:8629860 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Tnf tumor necrosis factor increases expression
increases response to substance
increases secretion
ISO Beryllium results in increased expression of TNF mRNA
TNF promoter polymorphism results in increased susceptibility to Beryllium
Beryllium results in increased secretion of TNF protein
CTD PMID:8629860 PMID:12449171 PMID:15127972 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
beryllium sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle, aorta increases expression ISO beryllium sulfate results in increased expression of ACTA2 mRNA CTD PMID:16314022 NCBI chr19:34,240,336...34,255,585
Ensembl chr19:34,241,090...34,255,590
JBrowse link
G Anxa5 annexin A5 increases expression ISO beryllium sulfate results in increased expression of ANXA5 mRNA CTD PMID:16314022 NCBI chr 3:36,448,923...36,475,887
Ensembl chr 3:36,448,923...36,475,894
JBrowse link
G Ccl3 chemokine (C-C motif) ligand 3 multiple interactions
increases secretion
ISO beryllium sulfate promotes the reaction [RUNX1 protein binds to CCL3 promoter]
beryllium sulfate results in increased secretion of CCL3 mRNA
CTD PMID:16314022 NCBI chr11:83,647,843...83,649,378
Ensembl chr11:83,647,844...83,649,355
JBrowse link
G Ccl4 chemokine (C-C motif) ligand 4 increases secretion ISO beryllium sulfate results in increased secretion of CCL4 mRNA CTD PMID:16314022 NCBI chr11:83,648,624...83,664,683
Ensembl chr11:83,662,584...83,664,683
JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 increases expression ISO beryllium sulfate results in increased expression of CCL5 mRNA CTD PMID:16314022 NCBI chr11:83,525,778...83,530,518
Ensembl chr11:83,525,778...83,530,518
JBrowse link
G Cd44 CD44 antigen increases expression ISO beryllium sulfate results in increased expression of CD44 mRNA CTD PMID:16314022 NCBI chr 2:102,811,141...102,901,669
Ensembl chr 2:102,811,141...102,901,665
JBrowse link
G Cd86 CD86 antigen increases expression ISO beryllium sulfate results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr16:36,568,956...36,666,158
Ensembl chr16:36,603,869...36,666,081
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) multiple interactions
increases expression
ISO beryllium sulfate promotes the reaction [TP53 protein binds to CDKN1A promoter]
beryllium sulfate results in increased expression of CDKN1A mRNA; beryllium sulfate results in increased expression of CDKN1A protein
CTD PMID:17395767 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727
JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A increases expression ISO beryllium sulfate results in increased expression of CDKN2A mRNA; beryllium sulfate results in increased expression of CDKN2A protein CTD PMID:17395767 NCBI chr 4:89,274,473...89,294,619
Ensembl chr 4:89,274,471...89,294,653
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP [beryllium sulfate co-treated with IFNG protein] results in increased expression of CREB1 protein CTD PMID:10755711 NCBI chr 1:64,532,794...64,604,548
Ensembl chr 1:64,532,645...64,604,548
JBrowse link
G Ctsl cathepsin L increases expression ISO beryllium sulfate results in increased expression of CTSL mRNA CTD PMID:16314022 NCBI chr13:64,361,890...64,370,772
Ensembl chr13:64,359,337...64,370,890
JBrowse link
G Cxcl1 chemokine (C-X-C motif) ligand 1 increases secretion ISO beryllium sulfate results in increased secretion of CXCL1 mRNA CTD PMID:16314022 NCBI chr 5:90,891,245...90,893,121
Ensembl chr 5:90,891,241...90,893,115
JBrowse link
G Cxcl3 chemokine (C-X-C motif) ligand 3 increases secretion ISO beryllium sulfate results in increased secretion of CXCL1 mRNA CTD PMID:16314022 NCBI chr 5:90,786,101...90,788,093
Ensembl chr 5:90,786,103...90,789,600
JBrowse link
G Egr2 early growth response 2 increases expression ISO beryllium sulfate results in increased expression of EGR2 mRNA CTD PMID:16314022 NCBI chr10:67,534,469...67,542,188
Ensembl chr10:67,535,475...67,542,188
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression
multiple interactions
EXP beryllium sulfate results in increased expression of FOS mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]; Dactinomycin inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]; Ro 31-8220 inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]
CTD PMID:11568973 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta increases expression
increases response to substance
ISO beryllium sulfate results in increased expression of HLA-DRB1 mRNA
HLA-DRB1 protein mutant form results in increased susceptibility to beryllium sulfate
CTD PMID:16272364 PMID:16314022 NCBI chr17:34,305,867...34,316,674
Ensembl chr17:34,305,867...34,316,674
JBrowse link
G H2-Q1 histocompatibility 2, Q region locus 1 increases expression ISO beryllium sulfate results in increased expression of HLA-A mRNA CTD PMID:16314022 NCBI chr17:35,320,525...35,328,142
Ensembl chr17:35,320,405...35,325,099
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 increases expression ISO beryllium sulfate results in increased expression of HNRNPA1 mRNA CTD PMID:16314022 NCBI chr15:103,239,943...103,246,698
Ensembl chr15:103,240,432...103,246,692
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases secretion
increases expression
ISO 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [beryllium sulfate results in increased expression of ICAM1 mRNA]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [beryllium sulfate results in increased secretion of ICAM1 protein]; Dimethyl Sulfoxide inhibits the reaction [beryllium sulfate results in increased secretion of ICAM1 protein]
beryllium sulfate results in increased expression of ICAM1 mRNA; beryllium sulfate results in increased expression of ICAM1 protein
CTD PMID:18539414 NCBI chr 9:21,015,940...21,028,814
Ensembl chr 9:21,015,985...21,028,817
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
ISO
EXP
beryllium sulfate results in increased expression of IFNG protein
[beryllium sulfate co-treated with IFNG protein] results in increased expression of CREB1 protein; [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUN protein; [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUNB protein; [beryllium sulfate co-treated with IFNG protein] results in increased expression of NFKB1 protein; beryllium sulfate promotes the reaction [IFNG protein results in increased expression of TNF protein]
CTD PMID:10755710 PMID:10755711 PMID:20974702 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Il18 interleukin 18 increases expression ISO beryllium sulfate results in increased expression of IL18 mRNA; beryllium sulfate results in increased expression of IL18 protein CTD PMID:16100009 NCBI chr 9:50,554,700...50,581,841
Ensembl chr 9:50,554,827...50,581,840
JBrowse link
G Il2 interleukin 2 increases expression EXP beryllium sulfate results in increased expression of IL2 mRNA CTD PMID:9328138 NCBI chr 3:37,120,713...37,125,954
Ensembl chr 3:37,120,523...37,125,959
JBrowse link
G Il5 interleukin 5 increases expression EXP beryllium sulfate results in increased expression of IL5 mRNA CTD PMID:9328138 NCBI chr11:53,720,794...53,725,103
Ensembl chr11:53,720,794...53,725,106
JBrowse link
G Il6 interleukin 6 increases expression EXP beryllium sulfate results in increased expression of IL6 mRNA CTD PMID:9328138 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Itgb3 integrin beta 3 increases expression ISO beryllium sulfate results in increased expression of ITGB3 mRNA CTD PMID:16314022 NCBI chr11:104,608,000...104,670,476
Ensembl chr11:104,608,000...104,670,476
JBrowse link
G Jun jun proto-oncogene multiple interactions
increases expression
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA]; [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUN protein; Dactinomycin inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA]; Ro 31-8220 inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA] CTD PMID:10755711 PMID:11568973 NCBI chr 4:95,049,036...95,052,222
Ensembl chr 4:95,049,034...95,052,222
JBrowse link
G Junb jun B proto-oncogene multiple interactions EXP [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUNB protein CTD PMID:10755711 NCBI chr 8:84,976,909...84,978,748
Ensembl chr 8:84,974,484...84,978,718
Ensembl chr 8:84,974,484...84,978,718
JBrowse link
G Myc myelocytomatosis oncogene increases expression ISO beryllium sulfate results in increased expression of MYC protein CTD PMID:2009323 NCBI chr15:61,985,341...61,990,361
Ensembl chr15:61,985,391...61,990,374
JBrowse link
G Nedd8 neural precursor cell expressed, developmentally down-regulated gene 8 increases expression ISO beryllium sulfate results in increased expression of NEDD8 mRNA CTD PMID:16314022 NCBI chr14:55,662,263...55,671,880
Ensembl chr14:55,662,263...55,672,124
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions EXP [beryllium sulfate co-treated with IFNG protein] results in increased expression of NFKB1 protein CTD PMID:10755711 NCBI chr 3:135,584,655...135,691,969
Ensembl chr 3:135,584,655...135,691,547
JBrowse link
G Nova1 NOVA alternative splicing regulator 1 increases expression ISO beryllium sulfate results in increased expression of NOVA1 mRNA CTD PMID:16314022 NCBI chr12:46,697,895...46,819,480
Ensembl chr12:46,694,517...46,818,929
JBrowse link
G Rhoa ras homolog family member A increases expression ISO beryllium sulfate results in increased expression of RHOA mRNA CTD PMID:16314022 NCBI chr 9:108,306,160...108,337,943
Ensembl chr 9:108,306,129...108,337,934
JBrowse link
G Rpl22 ribosomal protein L22 increases expression ISO beryllium sulfate results in increased expression of RPL22 mRNA CTD PMID:16314022 NCBI chr 4:152,324,436...152,334,082
Ensembl chr 4:152,325,742...152,334,071
JBrowse link
G Rpl30 ribosomal protein L30 increases expression ISO beryllium sulfate results in increased expression of RPL30 mRNA CTD PMID:16314022 NCBI chr15:34,440,505...34,443,276
Ensembl chr15:34,440,505...34,443,640
JBrowse link
G Rpl37a ribosomal protein L37a increases expression ISO beryllium sulfate results in increased expression of RPL37A mRNA CTD PMID:16314022 NCBI chr 1:72,711,260...72,713,813
Ensembl chr 1:72,711,290...72,713,813
JBrowse link
G Rps7 ribosomal protein S7 increases expression ISO beryllium sulfate results in increased expression of RPS7 mRNA CTD PMID:16314022 NCBI chr12:28,630,847...28,635,953
Ensembl chr12:28,630,854...28,635,953
JBrowse link
G Runx1 runt related transcription factor 1 multiple interactions ISO beryllium sulfate promotes the reaction [RUNX1 protein binds to CCL3 promoter] CTD PMID:16314022 NCBI chr16:92,601,466...92,826,074
Ensembl chr16:92,601,466...92,826,149
JBrowse link
G Serpinb2 serine (or cysteine) peptidase inhibitor, clade B, member 2 increases expression ISO beryllium sulfate results in increased expression of SERPINB2 mRNA CTD PMID:16314022 NCBI chr 1:107,500,892...107,525,600
Ensembl chr 1:107,511,423...107,535,478
JBrowse link
G Sftpd surfactant associated protein D increases expression ISO beryllium sulfate results in increased expression of SFTPD mRNA CTD PMID:16314022 NCBI chr14:41,172,212...41,185,198
Ensembl chr14:41,172,214...41,185,149
JBrowse link
G Tat tyrosine aminotransferase multiple interactions ISO beryllium sulfate inhibits the reaction [Hydrocortisone results in increased expression of TAT protein] CTD PMID:6120038 NCBI chr 8:109,986,078...109,999,804
Ensembl chr 8:109,990,437...109,999,803
JBrowse link
G Tmsb4x thymosin, beta 4, X chromosome increases expression ISO beryllium sulfate results in increased expression of TMSB4X mRNA CTD PMID:16314022 NCBI chr  X:167,207,093...167,213,479
Ensembl chr  X:167,207,093...167,209,315
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
EXP beryllium sulfate results in increased expression of TNF mRNA; beryllium sulfate results in increased expression of TNF protein
beryllium sulfate promotes the reaction [IFNG protein results in increased expression of TNF protein]
CTD PMID:10755710 PMID:10755711 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Trp53 transformation related protein 53 multiple interactions
increases expression
ISO beryllium sulfate promotes the reaction [TP53 protein binds to CDKN1A promoter]
beryllium sulfate results in increased expression of TP53 protein
CTD PMID:17395767 PMID:20974702 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
G Wnt4 wingless-type MMTV integration site family, member 4 increases expression ISO beryllium sulfate results in increased expression of WNT4 mRNA CTD PMID:16314022 NCBI chr 4:137,277,635...137,299,501
Ensembl chr 4:137,277,489...137,299,726
JBrowse link
beryllium(0) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin dependent kinase inhibitor 2A multiple interactions ISO [Beryllium results in increased methylation of CDKN2A promoter] which results in decreased expression of CDKN2A mRNA CTD PMID:11872642 NCBI chr 4:89,274,473...89,294,619
Ensembl chr 4:89,274,471...89,294,653
JBrowse link
G Esr1 estrogen receptor 1 (alpha) increases methylation ISO Beryllium results in increased methylation of ESR1 gene CTD PMID:11872642 NCBI chr10:4,611,989...5,005,633
Ensembl chr10:4,611,593...5,005,614
JBrowse link
G Hras Harvey rat sarcoma virus oncogene increases mutagenesis ISO Beryllium results in increased mutagenesis of HRAS gene CTD PMID:7545909 NCBI chr 7:141,189,934...141,194,019
Ensembl chr 7:141,189,105...141,194,005
JBrowse link
G Il1b interleukin 1 beta increases expression
affects expression
ISO Beryllium results in increased expression of IL1B mRNA
Beryllium affects the expression of IL1B mRNA
CTD PMID:8473757 PMID:8629860 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Tnf tumor necrosis factor increases response to substance
increases secretion
increases expression
ISO TNF promoter polymorphism results in increased susceptibility to Beryllium
Beryllium results in increased secretion of TNF protein
Beryllium results in increased expression of TNF mRNA
CTD PMID:8629860 PMID:12449171 PMID:15127972 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
calcium atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 multiple interactions ISO Calcium deficiency inhibits the reaction [ABCB11 protein results in increased export of Taurocholic Acid] CTD PMID:25862123 NCBI chr 2:69,238,282...69,342,616
Ensembl chr 2:69,238,282...69,342,616
JBrowse link
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A multiple interactions ISO Calcium deficiency inhibits the reaction [ABCB1 protein results in increased export of Xanthenes]; Calcium inhibits the reaction [Magnesium results in increased activity of ABCB1 protein] CTD PMID:2900677 PMID:25862123 NCBI chr 5:8,567,091...8,748,575
Ensembl chr 5:8,660,077...8,748,575
JBrowse link
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 multiple interactions ISO Calcium deficiency inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein] CTD PMID:25862123 NCBI chr19:43,782,308...43,838,332
Ensembl chr19:43,782,192...43,840,740
JBrowse link
G Aco2 aconitase 2, mitochondrial increases activity
multiple interactions
EXP Calcium results in increased activity of ACO2 protein
[Calcium results in increased activity of ACO2 protein] which results in increased reduction of thiazolyl blue; [Nicardipine results in decreased uptake of Calcium] which results in decreased activity of ACO2 protein
CTD PMID:12548706 NCBI chr15:81,872,463...81,915,137
Ensembl chr15:81,872,309...81,915,133
JBrowse link
G Actb actin, beta multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of ACTB mRNA CTD PMID:15913539 NCBI chr 5:142,903,115...142,907,976
Ensembl chr 5:142,903,115...142,906,754
JBrowse link
G Adcy5 adenylate cyclase 5 decreases activity
increases response to substance
ISO
EXP
Calcium results in decreased activity of ADCY5 protein
ADCY5 protein results in increased susceptibility to Calcium
CTD PMID:12065575 PMID:12869393 NCBI chr16:35,154,494...35,305,743
Ensembl chr16:35,154,877...35,305,738
JBrowse link
G Adcy9 adenylate cyclase 9 multiple interactions ISO Calcium inhibits the reaction [Miconazole results in increased activity of ADCY9 protein]; Tacrolimus inhibits the reaction [Calcium inhibits the reaction [Miconazole results in increased activity of ADCY9 protein]] CTD PMID:30607468 NCBI chr16:4,284,886...4,437,236
Ensembl chr16:4,287,529...4,420,498
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 increases abundance
affects abundance
multiple interactions
ISO ADCYAP1 protein results in increased abundance of Calcium
ADCYAP1 protein affects the abundance of Calcium
Calcium affects the reaction [ADCYAP1 protein results in increased expression of SELENOT mRNA]; SELENOT protein affects the reaction [ADCYAP1 protein results in increased abundance of Calcium]
CTD PMID:18198219 PMID:21039959 NCBI chr17:93,198,245...93,206,541
Ensembl chr17:93,199,017...93,206,537
JBrowse link
G Adgrl1 adhesion G protein-coupled receptor L1 multiple interactions ISO [alpha-latrotoxin binds to ADGRL1 protein] which results in increased uptake of Calcium; [black widow spider venom binds to ADGRL1 protein] which results in increased uptake of Calcium CTD PMID:10026162 NCBI chr 8:83,900,098...83,941,954
Ensembl chr 8:83,900,105...83,941,954
JBrowse link
G Adgrl2 adhesion G protein-coupled receptor L2 multiple interactions ISO [alpha-latrotoxin binds to ADGRL2 protein] which results in increased uptake of Calcium; [black widow spider venom binds to ADGRL2 protein] which results in increased uptake of Calcium CTD PMID:10026162 NCBI chr 3:148,815,586...148,989,096
Ensembl chr 3:148,815,583...148,990,555
JBrowse link
G Adm adrenomedullin decreases expression ISO Calcium results in decreased expression of ADM mRNA CTD PMID:20682585 NCBI chr 7:110,627,657...110,629,820
Ensembl chr 7:110,627,661...110,629,820
JBrowse link
G Adra1a adrenergic receptor, alpha 1a multiple interactions
affects transport
ISO [Epinephrine binds to and results in increased activity of ADRA1A protein] which results in increased transport of Calcium; [Phenylephrine binds to and results in increased activity of ADRA1A protein] which results in increased transport of Calcium; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of EIF4EBP1 protein]; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of MTOR protein]; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of RPS6KB1 protein]
5-methylurapidil inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; [A 61603 results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Epinephrine binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Oxymetazoline binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]
ADRA1A protein affects the transport of Calcium
CTD PMID:12935885 PMID:15306222 PMID:15639650 PMID:15672411 PMID:16498073 More... NCBI chr14:66,635,251...66,771,240
Ensembl chr14:66,635,251...66,771,168
JBrowse link
G Adra1b adrenergic receptor, alpha 1b multiple interactions ISO [Epinephrine binds to and results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; [Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium] CTD PMID:15306222 PMID:16498073 PMID:20030735 NCBI chr11:43,774,605...43,901,250
Ensembl chr11:43,774,606...43,901,210
JBrowse link
G Adra1d adrenergic receptor, alpha 1d multiple interactions ISO [Epinephrine binds to and results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; [Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium] CTD PMID:15306222 PMID:20030735 NCBI chr 2:131,545,357...131,562,497
Ensembl chr 2:131,545,850...131,562,283
JBrowse link
G Adra2a adrenergic receptor, alpha 2a multiple interactions ISO [Epinephrine binds to and results in increased activity of ADRA2A protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA2A protein] which results in increased abundance of Calcium CTD PMID:20030735 NCBI chr19:54,045,259...54,048,982
Ensembl chr19:54,044,151...54,048,982
JBrowse link
G Adra2b adrenergic receptor, alpha 2b multiple interactions ISO [Epinephrine binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; [Oxymetazoline binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; [xylometazoline binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium CTD PMID:20030735 NCBI chr 2:127,363,179...127,367,221
Ensembl chr 2:127,363,208...127,367,221
JBrowse link
G Adra2c adrenergic receptor, alpha 2c multiple interactions ISO [Epinephrine binds to and results in increased activity of ADRA2C protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA2C protein] which results in increased abundance of Calcium CTD PMID:20030735 NCBI chr 5:35,278,566...35,281,763
Ensembl chr 5:35,278,319...35,281,763
JBrowse link
G Adrb2 adrenergic receptor, beta 2 multiple interactions ISO [Terbutaline binds to and results in increased activity of ADRB2 protein] which affects the abundance of Calcium
[Benzo(a)pyrene binds to ADRB2 protein] which results in increased transport of Calcium; ADRB2 protein promotes the reaction [Benzo(a)pyrene results in increased transport of Calcium]
CTD PMID:10372813 PMID:22167199 NCBI chr18:62,177,713...62,179,981
Ensembl chr18:62,177,816...62,179,959
JBrowse link
G Ago2 argonaute RISC catalytic subunit 2 multiple interactions ISO Calcium affects the reaction [PICK1 protein binds to AGO2 protein]; Calcium deficiency inhibits the reaction [Excitatory Amino Acid Agonists inhibits the reaction [PICK1 protein binds to AGO2 protein]] CTD PMID:28404816 NCBI chr15:73,101,625...73,184,947
Ensembl chr15:73,095,844...73,184,935
JBrowse link
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) increases uptake
affects localization
multiple interactions
increases abundance
ISO
EXP
AGT protein results in increased uptake of Calcium
AGT protein affects the localization of Calcium
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [AGT protein affects the localization of Calcium]; bafilomycin A1 inhibits the reaction [AGT protein affects the localization of Calcium]; Heparin inhibits the reaction [AGT protein affects the localization of Calcium]; Losartan inhibits the reaction [AGT protein affects the localization of Calcium]; Saralasin inhibits the reaction [AGT protein affects the localization of Calcium]; Sirolimus inhibits the reaction [AGT protein affects the localization of Calcium]; xestospongin C inhibits the reaction [AGT protein affects the localization of Calcium]
[AGT protein results in increased abundance of Calcium] which results in increased abundance of Reactive Oxygen Species
Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]
benidipine inhibits the reaction [AGT protein results in increased uptake of Calcium]; Mibefradil inhibits the reaction [AGT protein results in increased uptake of Calcium]
CTD PMID:10660688 PMID:18331727 PMID:18854758 PMID:21613610 NCBI chr 8:124,556,587...124,569,706
Ensembl chr 8:124,556,534...124,569,706
JBrowse link
G Agtr1a angiotensin II receptor, type 1a affects expression ISO Calcium affects the expression of AGTR1A mRNA CTD PMID:15913539 NCBI chr13:30,336,356...30,382,867
Ensembl chr13:30,336,441...30,382,867
JBrowse link
G Agtr1b angiotensin II receptor, type 1b multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of AGTR1B mRNA CTD PMID:15913539 NCBI chr 3:20,314,473...20,367,177
Ensembl chr 3:20,314,473...20,367,177
JBrowse link
G Akap1 A kinase (PRKA) anchor protein 1 affects expression ISO Calcium affects the expression of AKAP1 mRNA CTD PMID:15913539 NCBI chr11:88,830,792...88,864,596
Ensembl chr11:88,830,792...88,864,586
JBrowse link
G Akap11 A kinase (PRKA) anchor protein 11 affects expression ISO Calcium affects the expression of AKAP11 mRNA CTD PMID:15913539 NCBI chr14:78,492,246...78,536,980
Ensembl chr14:78,492,246...78,536,808
JBrowse link
G Akp3 alkaline phosphatase 3, intestine, not Mn requiring affects binding ISO Calcium binds to ALPP protein CTD PMID:16815919 NCBI chr 1:87,124,954...87,128,728
Ensembl chr 1:87,124,973...87,127,912
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 affects abundance
affects expression
multiple interactions
affects response to substance
ISO AKT1 protein affects the abundance of Calcium
Calcium affects the expression of AKT1 mRNA
[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein; Calcium affects the reaction [P2RY1 protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; CAMKK2 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; PDK1 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; PX-866 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; STO 609 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; W 7 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]
AKT1 protein affects the susceptibility to Calcium
CTD PMID:15913539 PMID:16094411 PMID:16236484 PMID:28634229 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial multiple interactions EXP
ISO
ALDH2 protein inhibits the reaction [Ethanol affects the abundance of Calcium]
Calcium affects the reaction [ALDH2 gene SNP affects the abundance of Lead]
CTD PMID:17590987 PMID:28212632 NCBI chr 5:121,566,027...121,593,824
Ensembl chr 5:121,566,027...121,593,824
JBrowse link
G Alg2 asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase) affects binding ISO Calcium binds to ALG2 protein CTD PMID:18997320 NCBI chr 4:47,469,833...47,474,367
Ensembl chr 4:47,465,067...47,474,333
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions ISO Calcium promotes the reaction [L 708714 binds to ALOX5 protein] CTD PMID:7577949 NCBI chr 6:116,410,071...116,461,178
Ensembl chr 6:116,410,077...116,461,178
JBrowse link
G Anxa1 annexin A1 affects activity ISO Calcium affects the activity of ANXA1 protein CTD PMID:20655937 NCBI chr19:20,373,434...20,390,671
Ensembl chr19:20,373,428...20,390,944
JBrowse link
G Anxa5 annexin A5 multiple interactions ISO Calcium binds to and results in increased activity of ANXA5 protein; Calcium promotes the reaction [Phosphatidylserines binds to ANXA5 protein] CTD PMID:11578147 PMID:16076491 NCBI chr 3:36,448,923...36,475,887
Ensembl chr 3:36,448,923...36,475,894
JBrowse link
G Aoc1 amine oxidase, copper-containing 1 affects binding ISO AOC1 protein binds to Calcium CTD PMID:12072962 NCBI chr 6:48,895,255...48,909,188
Ensembl chr 6:48,872,896...48,909,188
JBrowse link
G Apoe apolipoprotein E affects abundance
affects expression
EXP
ISO
APOE protein affects the abundance of Calcium
Calcium affects the expression of APOE mRNA
CTD PMID:15913539 PMID:17899169 NCBI chr 7:19,696,244...19,701,310
Ensembl chr 7:19,696,109...19,699,188
JBrowse link
G Apom apolipoprotein M affects expression ISO Calcium affects the expression of APOM mRNA CTD PMID:15913539 NCBI chr17:35,128,997...35,131,801
Ensembl chr17:35,128,997...35,132,050
JBrowse link
G App amyloid beta (A4) precursor protein multiple interactions
increases uptake
affects abundance
EXP
ISO
2,4-Dinitrophenol affects the reaction [APP protein affects the abundance of Calcium]; 3-nitrophenol affects the reaction [APP protein affects the abundance of Calcium]; 4-anisidine affects the reaction [APP protein affects the abundance of Calcium]
APP protein modified form results in increased uptake of Calcium; APP protein results in increased uptake of Calcium
Calcium deficiency inhibits the reaction [APP protein modified form results in increased uptake of Calcium]; EDN3 protein inhibits the reaction [APP protein results in increased uptake of Calcium]; Flurbiprofen inhibits the reaction [APP protein results in increased uptake of Calcium]; Ibuprofen inhibits the reaction [APP protein results in increased uptake of Calcium]; Indomethacin inhibits the reaction [APP protein results in increased uptake of Calcium]; Nimodipine inhibits the reaction [APP protein results in increased uptake of Calcium]; Ruthenium Red inhibits the reaction [APP protein modified form results in increased uptake of Calcium]; Salicylates inhibits the reaction [APP protein results in increased uptake of Calcium]; sulindac sulfide inhibits the reaction [APP protein results in increased uptake of Calcium]
CTD PMID:12383957 PMID:18648507 PMID:18949129 PMID:24457011 NCBI chr16:84,952,666...85,175,255
Ensembl chr16:84,949,685...85,173,766
JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions EXP
ISO
ARRB2 protein affects the abundance of and affects the localization of Calcium
ARRB2 promotes the reaction [carvedilol results in increased uptake of Calcium]
CTD PMID:16210646 PMID:21078978 NCBI chr11:70,432,485...70,440,828
Ensembl chr11:70,432,635...70,440,828
JBrowse link
G Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of ATP1A1 mRNA CTD PMID:15913539 NCBI chr 3:101,576,219...101,604,707
Ensembl chr 3:101,576,219...101,604,684
JBrowse link
G Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide multiple interactions ISO Calcium affects the reaction [Ouabain results in increased expression of ATP1B1 mRNA] CTD PMID:11204457 NCBI chr 1:164,437,099...164,458,355
Ensembl chr 1:164,437,109...164,458,355
JBrowse link
G Atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 affects transport
multiple interactions
ISO
EXP
ATP2A1 protein affects the transport of Calcium
[Phenols results in decreased activity of ATP2A1 protein] which results in decreased transport of Calcium
CTD PMID:11230109 PMID:18773882 NCBI chr 7:126,445,858...126,463,103
Ensembl chr 7:126,445,858...126,463,108
JBrowse link
G Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 affects abundance
affects transport
multiple interactions
affects uptake
affects export
EXP
ISO
ATP2A2 protein affects the abundance of Calcium
ATP2A2 protein affects the transport of Calcium
[[Phenylephrine results in increased activity of SLC9A1 protein] which results in increased transport of Calcium] which results in increased expression of ATP2A2 protein; [Phenylephrine results in decreased expression of ATP2A2 protein] which results in decreased transport of Calcium; [Thapsigargin results in decreased activity of ATP2A2 protein] which results in decreased transport of Calcium
PPP3R1 gene mutant form inhibits the reaction [ATP2A2 protein affects the transport of Calcium]
ATP2A2 protein alternative form affects the uptake of Calcium
ATP2A2 protein alternative form affects the export of Calcium
CTD PMID:11679415 PMID:16236312 PMID:17287366 PMID:19244478 PMID:19328205 More... NCBI chr 5:122,453,513...122,502,225
Ensembl chr 5:122,453,513...122,502,225
JBrowse link
G Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 multiple interactions
increases export
ISO caloxin 1b1 inhibits the reaction [ATP2B1 protein results in increased export of Calcium] CTD PMID:16452157 NCBI chr10:98,914,630...99,026,143
Ensembl chr10:98,914,406...99,026,143
JBrowse link
G Atp2b4 ATPase, Ca++ transporting, plasma membrane 4 increases export
multiple interactions
ISO ATP2B4 protein results in increased export of Calcium
caloxin 1b1 inhibits the reaction [ATP2B4 protein results in increased export of Calcium]
CTD PMID:16452157 NCBI chr 1:133,702,674...133,801,059
Ensembl chr 1:133,699,457...133,801,041
JBrowse link
G Atp8b1 ATPase, class I, type 8B, member 1 multiple interactions ISO Calcium inhibits the reaction [ATP8B1 protein results in increased transport of Phosphatidylserines] CTD PMID:11584374 NCBI chr18:64,528,979...64,661,272
Ensembl chr18:64,528,967...64,661,267
JBrowse link
G Avp arginine vasopressin multiple interactions
increases uptake
increases abundance
ISO 1-Butanol inhibits the reaction [AVP protein results in increased abundance of Calcium]; 2-(4-amylcinnamoyl)amino-4-chlorobenzoic acid inhibits the reaction [AVP protein results in increased abundance of Calcium]; [[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; [[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein; [AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium; [AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium; AVP protein results in increased import of and results in increased abundance of Calcium; Carvedilol inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium]; Chromium affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; Chromium affects the reaction [INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; chromium tripicolinate affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; chromium tripicolinate affects the reaction [INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; INS1 protein affects the reaction [Chromium affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; INS1 protein affects the reaction [chromium tripicolinate affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; Nicardipine inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium]; Nifedipine inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium] CTD PMID:9446840 PMID:11356622 PMID:11553362 PMID:14711191 PMID:21039959 NCBI chr 2:130,580,620...130,582,588
Ensembl chr 2:130,580,620...130,582,554
JBrowse link
G Avpr1a arginine vasopressin receptor 1A multiple interactions ISO [[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; [[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein; [AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium; [NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium; Carbachol promotes the reaction [[NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium]; Nicardipine inhibits the reaction [[NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium]; Nicardipine inhibits the reaction [Carbachol promotes the reaction [[NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium]] CTD PMID:11553362 PMID:12646291 NCBI chr10:122,448,499...122,453,453
Ensembl chr10:122,448,499...122,453,452
JBrowse link
G Avpr2 arginine vasopressin receptor 2 affects expression ISO Calcium affects the expression of AVPR2 mRNA CTD PMID:15913539 NCBI chr  X:73,891,765...73,894,428
Ensembl chr  X:73,892,102...73,895,502
JBrowse link
G Axin1 axin 1 affects expression ISO Calcium affects the expression of AXIN1 mRNA CTD PMID:15913539 NCBI chr17:26,131,217...26,195,811
Ensembl chr17:26,138,688...26,195,811
JBrowse link
G Bad BCL2-associated agonist of cell death affects expression ISO Calcium affects the expression of BAD mRNA CTD PMID:15913539 NCBI chr19:6,941,861...6,951,905
Ensembl chr19:6,941,861...6,951,899
JBrowse link
G Bdkrb1 bradykinin receptor, beta 1 multiple interactions ISO 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [[kallidin, des-Arg(10)- results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]; [kallidin, des-Arg(10)- results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium; Sodium affects the reaction [[kallidin, des-Arg(10)- results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]
[kallidin, des-Arg(10)- binds to and results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium; bradykinin, Lys-Leu(8)-desArg(9)- inhibits the reaction [[kallidin, des-Arg(10)- binds to and results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]; Indomethacin inhibits the reaction [[kallidin, des-Arg(10)- binds to and results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]
CTD PMID:15703175 PMID:22554775 NCBI chr12:105,604,091...105,605,511
Ensembl chr12:105,603,085...105,605,428
JBrowse link
G Bdkrb2 bradykinin receptor, beta 2 multiple interactions ISO
EXP
BDKRB2 protein affects the reaction [KNG1 protein affects the abundance of Calcium]
BDKRB2 protein affects the reaction [pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]]
CTD PMID:16473424 PMID:18054572 NCBI chr12:105,563,172...105,595,244
Ensembl chr12:105,563,226...105,595,237
JBrowse link
G Bdnf brain derived neurotrophic factor multiple interactions
increases transport
EXP
ISO
[Cadmium results in decreased transport of Calcium] inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein]; Calcium affects the reaction [Oxygen deficiency results in increased secretion of BDNF protein]
BDNF protein results in increased transport of Calcium
3,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]; 3,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide promotes the reaction [Tetrodotoxin inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]]; Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]; Tetrodotoxin inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]
CTD PMID:16553631 PMID:26095976 NCBI chr 2:109,674,700...109,727,043
Ensembl chr 2:109,674,700...109,727,007
JBrowse link
G Best1 bestrophin 1 increases activity
multiple interactions
EXP Calcium results in increased activity of BEST1 protein
[PAR-1-activating peptide results in increased abundance of Calcium] which results in increased activity of BEST1 protein
CTD PMID:19828819 NCBI chr19:9,985,172...10,001,633
Ensembl chr19:9,985,174...10,001,633
JBrowse link
G Bmp4 bone morphogenetic protein 4 affects expression
multiple interactions
ISO Calcium affects the expression of BMP4 mRNA
[Calcium binds to MGP protein] which binds to and results in decreased activity of BMP4 protein; [Edetic Acid inhibits the reaction [Calcium binds to MGP protein]] inhibits the reaction [MGP protein binds to BMP4 protein]
CTD PMID:15913539 PMID:18369157 NCBI chr14:46,383,525...46,390,669
Ensembl chr14:46,383,520...46,390,669
JBrowse link
G Btk Bruton agammaglobulinemia tyrosine kinase affects transport EXP BTK protein affects the transport of Calcium CTD PMID:12848851 NCBI chr  X:134,542,334...134,583,628
Ensembl chr  X:134,542,336...134,583,570
JBrowse link
G Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit increases transport
multiple interactions
ISO CACNA1A protein results in increased transport of Calcium
Allethrins inhibits the reaction [CACNA1A protein results in increased transport of Calcium]
CTD PMID:14634047 NCBI chr 8:84,338,631...84,640,251
Ensembl chr 8:84,338,639...84,640,246
JBrowse link
G Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit multiple interactions
decreases uptake
increases transport
ISO decamethrin inhibits the reaction [CACNA1B protein results in increased transport of Calcium]; decamethrin promotes the reaction [CACNA1B gene mutant form results in increased transport of Calcium]
CACNA1B protein alternative form results in decreased uptake of Calcium
CTD PMID:18383452 PMID:22891239 NCBI chr 2:24,603,860...24,763,200
Ensembl chr 2:24,603,887...24,763,152
JBrowse link
G Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit increases transport
multiple interactions
ISO CACNA1C protein results in increased transport of Calcium
[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium; [CACNA2D4 protein binds to CACNA1C protein binds to CACNB3 protein] which results in increased transport of Calcium; CACNA2D4 protein promotes the reaction [[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium]
Allethrins inhibits the reaction [CACNA1C protein results in increased transport of Calcium]
CTD PMID:12181424 PMID:14634047 PMID:15299022 NCBI chr 6:118,587,240...119,197,384
Ensembl chr 6:118,587,240...119,196,890
Ensembl chr 6:118,587,240...119,196,890
JBrowse link
G Cacna1d calcium channel, voltage-dependent, L type, alpha 1D subunit affects transport
multiple interactions
EXP
ISO
CACNA1D protein affects the transport of Calcium
CACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Calcium]
[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium; [CACNA1D protein results in increased uptake of Calcium] which affects the localization of SLC2A2 protein; [CACNA1D protein results in increased uptake of Calcium] which results in increased phosphorylation of MYL9 protein; CACNA2D1 protein promotes the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]; gabapentin affects the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]; SLC5A1 protein affects the reaction [CACNA1D protein results in increased uptake of Calcium]
CTD PMID:15357422 PMID:17272349 PMID:19796812 PMID:27798183 NCBI chr14:30,039,941...30,491,156
Ensembl chr14:30,039,939...30,491,455
JBrowse link
G Cacna1e calcium channel, voltage-dependent, R type, alpha 1E subunit increases transport
multiple interactions
ISO CACNA1E protein results in increased transport of Calcium
Calcium inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]
Cadmium inhibits the reaction [CACNA1E protein results in increased transport of Calcium]; Nickel inhibits the reaction [CACNA1E protein results in increased transport of Calcium]
CTD PMID:10627594 PMID:10669483 PMID:12663092 NCBI chr 1:154,390,806...154,884,785
Ensembl chr 1:154,390,731...154,884,501
JBrowse link
G Cacna1f calcium channel, voltage-dependent, alpha 1F subunit increases transport EXP CACNA1F protein results in increased transport of Calcium CTD PMID:14744918 NCBI chr  X:7,607,103...7,635,196
Ensembl chr  X:7,607,083...7,635,196
JBrowse link
G Cacna1g calcium channel, voltage-dependent, T type, alpha 1G subunit increases transport
multiple interactions
EXP
ISO
CACNA1G protein results in increased transport of Calcium
Allethrins inhibits the reaction [CACNA1G protein results in increased transport of Calcium]
CACNG2 protein affects the reaction [CACNA1G protein results in increased transport of Calcium]; CACNG4 protein affects the reaction [CACNA1G protein results in increased transport of Calcium]; CACNG5 protein affects the reaction [CACNA1G protein results in increased transport of Calcium]
CTD PMID:10734232 PMID:11073957 PMID:14634047 NCBI chr11:94,408,391...94,474,400
Ensembl chr11:94,408,391...94,474,198
JBrowse link
G Cacna1h calcium channel, voltage-dependent, T type, alpha 1H subunit increases transport
multiple interactions
ISO
EXP
CACNA1H protein results in increased transport of Calcium
Amiloride inhibits the reaction [CACNA1H protein results in increased transport of Calcium]; Nickel inhibits the reaction [CACNA1H protein results in increased transport of Calcium]
Amiloride inhibits the reaction [CACNA1H protein results in increased transport of Calcium]; Mibefradil inhibits the reaction [CACNA1H protein results in increased transport of Calcium]; Nickel inhibits the reaction [CACNA1H protein results in increased transport of Calcium]
CTD PMID:9930755 PMID:11073957 PMID:11897840 NCBI chr17:25,374,285...25,436,334
Ensembl chr17:25,374,285...25,433,783
JBrowse link
G Cacna1i calcium channel, voltage-dependent, alpha 1I subunit increases transport ISO CACNA1I protein results in increased transport of Calcium CTD PMID:11073957 NCBI chr15:80,287,238...80,398,292
Ensembl chr15:80,287,238...80,398,279
JBrowse link
G Cacna2d1 calcium channel, voltage-dependent, alpha2/delta subunit 1 multiple interactions
increases transport
EXP
ISO
[gabapentin results in decreased activity of CACNA2D1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]; CACNA2D1 protein affects the reaction [Potassium Chloride results in increased transport of Calcium]
CACNA2D1 protein promotes the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]
CACNA2D1 protein results in increased transport of Calcium
CTD PMID:15474003 PMID:17442347 PMID:17881535 PMID:19796812 NCBI chr 5:15,934,264...16,374,511
Ensembl chr 5:15,934,691...16,374,511
JBrowse link
G Cacna2d2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 affects transport
multiple interactions
EXP CACNA2D2 protein affects the transport of Calcium
CACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Calcium]
CTD PMID:14660671 PMID:27798183 NCBI chr 9:107,399,733...107,529,346
Ensembl chr 9:107,399,612...107,529,343
JBrowse link
G Cacna2d4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 multiple interactions ISO [CACNA2D4 protein binds to CACNA1C protein binds to CACNB3 protein] which results in increased transport of Calcium; CACNA2D4 protein promotes the reaction [[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium] CTD PMID:12181424 NCBI chr 6:119,236,524...119,352,407
Ensembl chr 6:119,236,526...119,352,407
JBrowse link
G Cacnb3 calcium channel, voltage-dependent, beta 3 subunit multiple interactions ISO [CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium; [CACNA2D4 protein binds to CACNA1C protein binds to CACNB3 protein] which results in increased transport of Calcium; CACNA2D4 protein promotes the reaction [[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium]
[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium; CACNA2D1 protein promotes the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]; gabapentin affects the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]
CTD PMID:12181424 PMID:19796812 NCBI chr15:98,628,436...98,644,536
Ensembl chr15:98,630,840...98,644,529
JBrowse link
G Cacng2 calcium channel, voltage-dependent, gamma subunit 2 multiple interactions EXP CACNG2 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] CTD PMID:10734232 NCBI chr15:77,991,919...78,120,220
Ensembl chr15:77,991,748...78,120,028
JBrowse link
G Cacng4 calcium channel, voltage-dependent, gamma subunit 4 multiple interactions EXP CACNG4 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] CTD PMID:10734232 NCBI chr11:107,732,357...107,794,706
Ensembl chr11:107,732,357...107,794,557
JBrowse link
G Cacng5 calcium channel, voltage-dependent, gamma subunit 5 multiple interactions EXP CACNG5 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] CTD PMID:10734232 NCBI chr11:107,874,604...107,915,055
Ensembl chr11:107,874,605...107,915,055
JBrowse link
G Calb1 calbindin 1 affects expression ISO Calcium affects the expression of CALB1 mRNA CTD PMID:15913539 NCBI chr 4:15,881,264...15,906,709
Ensembl chr 4:15,881,264...15,908,064
JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha multiple interactions
increases expression
EXP
ISO
rimabotulinumtoxinB inhibits the reaction [[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein]; rimabotulinumtoxinB inhibits the reaction [[Potassium co-treated with Calcium] results in increased secretion of CALCA protein]
Calcium promotes the reaction [Lipopolysaccharides results in increased expression of CALCA mRNA]
Calcium results in increased expression of CALCA mRNA
Calcium results in increased expression of CALCA protein
[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein; [KNG1 protein alternative form co-treated with Calcium] results in increased secretion of CALCA protein; [Potassium co-treated with Calcium] results in increased secretion of CALCA protein; [Sumatriptan results in increased abundance of Calcium] inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA]; botulinum toxin type D inhibits the reaction [[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein]; botulinum toxin type D inhibits the reaction [[Potassium co-treated with Calcium] results in increased secretion of CALCA protein]; Botulinum Toxins, Type A inhibits the reaction [[Potassium co-treated with Calcium] results in increased secretion of CALCA protein]; Calcium affects the reaction [Capsaicin inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Calcium affects the reaction [Capsaicin inhibits the reaction [mustard oil results in increased secretion of CALCA protein]]; Calcium affects the reaction [mustard oil inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Calcium deficiency inhibits the reaction [safranal results in increased secretion of CALCA protein]; Calcium inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA]
CTD PMID:2470235 PMID:12574409 PMID:17590514 PMID:17666428 PMID:20682585 More... NCBI chr 7:114,625,981...114,636,910
Ensembl chr 7:114,631,478...114,636,357
JBrowse link
G Calm1 calmodulin 1 multiple interactions
affects binding
ISO Calcium affects the folding of [CALM1 protein binds to RYR1 protein modified form]; Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]
Calcium binds to CALM1 protein
[Calcium binds to CALM1 protein] promotes the reaction [NOS1 protein results in increased chemical synthesis of Nitric Oxide]; [Calcium binds to CALM1 protein] which binds to and affects the folding of and results in increased activity of NOS1 protein; Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]; Calcium affects the reaction [CALM1 protein modified form binds to and affects the activity of RYR1 protein]; Calcium binds to and affects the folding of CALM1 protein
CTD PMID:15381065 PMID:15628869 PMID:17098364 NCBI chr12:100,199,435...100,209,824
Ensembl chr12:100,199,435...100,209,814
JBrowse link
G Calr calreticulin affects response to substance
multiple interactions
EXP CALR protein affects the susceptibility to Calcium
CALR protein promotes the reaction [KNG1 protein modified form results in increased abundance of Calcium]
CTD PMID:7961812 NCBI chr 8:84,842,088...84,846,931
Ensembl chr 8:84,841,850...84,846,934
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II, delta affects expression ISO Calcium affects the expression of CAMK2D mRNA CTD PMID:15913539 NCBI chr 3:126,595,487...126,846,326
Ensembl chr 3:126,596,302...126,846,326
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2, beta multiple interactions ISO CAMKK2 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein] CTD PMID:28634229 NCBI chr 5:122,718,380...122,779,522
Ensembl chr 5:122,731,170...122,779,409
JBrowse link
G Capn1 calpain 1 multiple interactions
increases cleavage
increases activity
ISO [Caffeine co-treated with Alprazolam] promotes the reaction [Calcium results in increased activity of CAPN1 protein]; [Calcium co-treated with CAPN1 protein] results in increased degradation of TP73 protein modified form; [sodium arsenite results in increased abundance of Arsenic] promotes the reaction [[Calcium results in increased cleavage of CAPN1 protein] which results in increased degradation of CAPN1 protein]
calpain inhibitor III inhibits the reaction [Calcium results in increased activity of CAPN1 protein]
CTD PMID:19490937 PMID:21516125 PMID:21985864 PMID:31398423 NCBI chr19:5,988,545...6,015,825
Ensembl chr19:5,988,545...6,015,897
JBrowse link
G Car4 carbonic anhydrase 4 affects expression ISO Calcium affects the expression of CA4 mRNA CTD PMID:15913539 NCBI chr11:84,957,754...84,966,054
Ensembl chr11:84,957,786...84,966,044
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in increased expression of CASP3 mRNA]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in increased expression of CASP3 mRNA]; Calcium affects the reaction [sodium arsenite results in increased expression of CASP3 mRNA]
Calcium deficiency inhibits the reaction [Dasatinib results in increased activity of CASP3 protein]; Calcium deficiency inhibits the reaction [Ionomycin results in increased activity of CASP3 protein]
CTD PMID:24184500 PMID:29803841 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp9 caspase 9 multiple interactions ISO [Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in increased expression of CASP9 mRNA]]; Calcium affects the reaction [sodium arsenite results in increased expression of CASP9 mRNA] CTD PMID:24184500 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976
JBrowse link
G Casr calcium-sensing receptor increases phosphorylation
multiple interactions
increases uptake
increases activity
affects expression
decreases response to substance
increases response to substance
ISO Calcium results in increased phosphorylation of CASR protein
[Aluminum binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Calcium binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Calcium binds to and results in increased activity of CASR protein] which results in increased abundance of Inositol Phosphates; [Gadolinium binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Magnesium binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Neomycin binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; Calcium binds to and results in increased activity of CASR protein; Gadolinium inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]
CASR protein results in increased uptake of Calcium
Calcium results in increased activity of CASR protein
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [CASR protein results in increased uptake of Calcium]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [CASR protein results in increased uptake of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]; 2-aminoethoxydiphenyl borate inhibits the reaction [CASR protein results in increased uptake of Calcium]; [2-quinoxaline-carboxamide-N-adamantan-1-yl binds to and results in decreased activity of CASR protein] inhibits the reaction [Nickel results in increased abundance of Calcium]; [Calcium binds to and results in increased activity of CASR protein] which results in increased uptake of Calcium; [CASR protein mutant form results in increased susceptibility to Calcium] which results in increased abundance of Inositol 1,4,5-Trisphosphate; [Spermine binds to and results in increased activity of CASR protein] which results in increased uptake of Calcium; bisindolylmaleimide I inhibits the reaction [NPS R-467 promotes the reaction [Calcium results in increased phosphorylation of CASR protein]]; Calcium Chloride promotes the reaction [Calcium results in increased phosphorylation of CASR protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of WNT5A protein]; CASR protein affects the reaction [Nickel results in increased abundance of Calcium]; CASR protein promotes the reaction [TRPC6 protein results in increased uptake of Calcium]; chelerythrine inhibits the reaction [CASR protein results in increased uptake of Calcium]; Flufenamic Acid promotes the reaction [CASR protein results in increased uptake of Calcium]; Lanthanum inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]; Lanthanum inhibits the reaction [CASR protein results in increased uptake of Calcium]; methyl-beta-cyclodextrin inhibits the reaction [CASR protein results in increased uptake of Calcium]; N-(2-chlorophenylpropyl)-1-(3-methoxyphenyl)ethylamine affects the reaction [CASR gene mutant form results in increased susceptibility to Calcium]; N-(2-chlorophenylpropyl)-1-(3-methoxyphenyl)ethylamine promotes the reaction [CASR protein results in increased susceptibility to Calcium]; NPS R-467 promotes the reaction [Calcium results in increased phosphorylation of CASR protein]; Pertussis Toxin inhibits the reaction [CASR protein results in increased uptake of Calcium]
Calcium affects the expression of CASR mRNA; Calcium affects the expression of CASR protein
CASR protein mutant form results in decreased susceptibility to Calcium
CASR gene mutant form results in increased susceptibility to Calcium; CASR protein mutant form results in increased susceptibility to Calcium
CTD PMID:7874174 PMID:9011580 PMID:10231437 PMID:11071898 PMID:11089548 More... NCBI chr16:36,490,585...36,562,141
Ensembl chr16:36,493,696...36,562,141
JBrowse link
G Cat catalase multiple interactions ISO CAT protein inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; CAT protein inhibits the reaction [Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]]
[Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in decreased activity of CAT protein]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in decreased activity of CAT protein]; [Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of CAT protein]; Calcium affects the reaction [sodium arsenite results in decreased activity of CAT protein]
CTD PMID:21127073 PMID:22534743 PMID:24184500 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Cav1 caveolin 1, caveolae protein affects transport EXP CAV1 protein affects the transport of Calcium CTD PMID:16428350 NCBI chr 6:17,306,335...17,341,328
Ensembl chr 6:17,306,335...17,341,452
JBrowse link
G Cav3 caveolin 3 multiple interactions ISO CAV3 protein affects the reaction [Potassium Chloride results in increased uptake of Calcium] CTD PMID:21294223 NCBI chr 6:112,459,505...112,472,872
Ensembl chr 6:112,459,505...112,472,872
JBrowse link
G Cbfb core binding factor beta affects expression ISO Calcium affects the expression of CBFB mRNA CTD PMID:15913539 NCBI chr 8:105,170,674...105,217,989
Ensembl chr 8:105,170,674...105,217,989
JBrowse link
G Ccl11 chemokine (C-C motif) ligand 11 increases uptake ISO CCL11 protein results in increased uptake of Calcium CTD PMID:10984371 NCBI chr11:82,057,832...82,062,955
Ensembl chr11:82,057,823...82,062,955
JBrowse link
G Ccl12 chemokine (C-C motif) ligand 12 increases uptake ISO CCL13 protein results in increased uptake of Calcium CTD PMID:10984371 NCBI chr11:82,101,845...82,103,399
Ensembl chr11:82,101,845...82,103,400
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 increases abundance
multiple interactions
increases uptake
ISO CCL2 protein results in increased abundance of Calcium
montelukast inhibits the reaction [CCL2 protein results in increased abundance of Calcium]; Piperidines analog inhibits the reaction [CCL2 protein results in increased uptake of Calcium]; resveratrol inhibits the reaction [CCL2 protein affects the localization of Calcium]
CTD PMID:10843593 PMID:10984371 PMID:16212921 PMID:16771778 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Ccl3 chemokine (C-C motif) ligand 3 multiple interactions ISO resveratrol inhibits the reaction [CCL3 protein affects the localization of Calcium] CTD PMID:16212921 NCBI chr11:83,647,843...83,649,378
Ensembl chr11:83,647,844...83,649,355
JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 increases uptake ISO CCL5 protein results in increased uptake of Calcium CTD PMID:10984371 NCBI chr11:83,525,778...83,530,518
Ensembl chr11:83,525,778...83,530,518
JBrowse link
G Ccl7 chemokine (C-C motif) ligand 7 increases uptake
multiple interactions
ISO CCL7 protein results in increased uptake of Calcium
Piperidines analog inhibits the reaction [CCL7 protein results in increased uptake of Calcium]
CTD PMID:10843593 PMID:10984371 NCBI chr11:82,045,712...82,047,525
Ensembl chr11:82,045,712...82,047,525
JBrowse link
G Ccnd1 cyclin D1 affects expression
increases expression
ISO Calcium affects the expression of CCND1 mRNA
Calcium results in increased expression of CCND1 mRNA
CTD PMID:15913539 PMID:24658506 NCBI chr 7:144,929,931...144,939,831
Ensembl chr 7:144,929,931...144,939,925
JBrowse link
G Ccr10 chemokine (C-C motif) receptor 10 affects abundance ISO CCR10 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr11:101,172,998...101,175,443
Ensembl chr11:101,172,997...101,175,443
JBrowse link
G Ccr4 chemokine (C-C motif) receptor 4 affects abundance ISO CCR4 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr 9:114,490,316...114,505,476
Ensembl chr 9:114,490,316...114,504,916
JBrowse link
G Ccr8 chemokine (C-C motif) receptor 8 affects abundance ISO CCR8 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr 9:120,092,133...120,094,906
Ensembl chr 9:120,092,114...120,094,906
JBrowse link
G Ccr9 chemokine (C-C motif) receptor 9 affects abundance ISO CCR9 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr 9:123,767,211...123,783,457
Ensembl chr 9:123,678,439...123,784,330
JBrowse link
G Cd28 CD28 antigen multiple interactions
increases abundance
ISO 1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [CD28 protein results in increased abundance of Calcium]; 2-aminoethoxydiphenylborane inhibits the reaction [CD28 protein results in increased abundance of Calcium]; 5-diisopropoxyphosphoryl-5-methyl-1-pyrroline-N-oxide inhibits the reaction [CD28 protein results in increased abundance of Calcium]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [CD28 protein results in increased abundance of Calcium] CTD PMID:14607919 NCBI chr 1:60,746,388...60,773,359
Ensembl chr 1:60,716,800...60,773,359
JBrowse link
G Cd38 CD38 antigen multiple interactions EXP CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]; CD38 protein inhibits the reaction [CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]] CTD PMID:20200208 NCBI chr 5:43,868,809...43,912,374
Ensembl chr 5:43,868,553...43,912,375
JBrowse link
G Cdc42 cell division cycle 42 multiple interactions EXP Calcium promotes the reaction [PAFAH1B1 protein binds to IQGAP1 protein binds to CDC42 protein] CTD PMID:16369480 NCBI chr 4:137,319,696...137,357,759
Ensembl chr 4:137,319,696...137,357,720
JBrowse link
G Cdc42bpb CDC42 binding protein kinase beta affects expression ISO Calcium affects the expression of CDC42BPB mRNA CTD PMID:15913539 NCBI chr12:111,292,972...111,379,313
Ensembl chr12:111,292,976...111,377,718
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) increases cleavage
multiple interactions
ISO Calcium results in increased cleavage of CDK5R1 protein
calpeptin inhibits the reaction [Calcium results in increased cleavage of CDK5R1 protein]
CTD PMID:18242949 NCBI chr11:80,477,023...80,481,184
Ensembl chr11:80,477,023...80,481,184
JBrowse link
G Cebpb CCAAT/enhancer binding protein (C/EBP), beta affects expression ISO Calcium affects the expression of CEBPB mRNA CTD PMID:15913539 NCBI chr 2:167,688,915...167,690,432
Ensembl chr 2:167,688,915...167,690,418
JBrowse link
G Cerk ceramide kinase multiple interactions ISO Calcium affects the reaction [CERK protein results in increased phosphorylation of Ceramides] CTD PMID:16269826 NCBI chr15:86,139,101...86,186,259
Ensembl chr15:86,139,128...86,186,141
JBrowse link
G Cfb complement factor B multiple interactions EXP CFD protein affects the reaction [[cobra venom factor co-treated with Magnesium co-treated with Calcium] results in increased cleavage of CFB protein] CTD PMID:11724962 NCBI chr17:34,856,374...34,862,514
Ensembl chr17:34,856,374...34,862,518
JBrowse link
G Cfd complement factor D (adipsin) multiple interactions EXP CFD protein affects the reaction [[cobra venom factor co-treated with Magnesium co-treated with Calcium] results in increased cleavage of CFB protein] CTD PMID:11724962 NCBI chr10:79,890,853...79,892,655
Ensembl chr10:79,890,853...79,892,655
JBrowse link
G Cfl1 cofilin 1, non-muscle multiple interactions ISO [Capsaicin results in decreased phosphorylation of and results in increased activity of CFL1 protein] which results in increased import of Calcium CTD PMID:17303079 NCBI chr19:5,490,455...5,494,031
Ensembl chr19:5,490,455...5,495,201
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1, CNS multiple interactions ISO
EXP
[Acetylcholine results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; [Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; [Pilocarpine results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; CHRM1 protein promotes the reaction [Methacholine Compounds results in increased abundance of Calcium]
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; 1-oleoyl-2-acetylglycerol promotes the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; [Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; Atropine inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Flufenamic Acid inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Gadolinium inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Lanthanum inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Pirenzepine inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Thapsigargin inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]
[[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; [[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein
CTD PMID:11527950 PMID:11553362 PMID:12456425 PMID:18316702 NCBI chr19:8,664,005...8,683,606
Ensembl chr19:8,663,789...8,683,587
JBrowse link
G Chrna4 cholinergic receptor, nicotinic, alpha polypeptide 4 multiple interactions ISO [CHRNA4 protein co-treated with CHRNB2 protein mutant form] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein co-treated with CHRNB2 protein] affects the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein mutant form co-treated with CHRNB2 protein] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine] CTD PMID:12754307 NCBI chr 2:181,022,311...181,043,579
Ensembl chr 2:181,018,380...181,043,546
JBrowse link
G Chrna7 cholinergic receptor, nicotinic, alpha polypeptide 7 multiple interactions ISO [[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium; [[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] which results in increased uptake of Calcium] inhibits the reaction [CHRNA7 protein results in decreased susceptibility to Okadaic Acid]; [Acetylcholine results in increased activity of CHRNA7 protein] which results in increased uptake of Calcium; [Bungarotoxins binds to and results in increased activity of CHRNA7 protein] which results in increased transport of Calcium; [methyllycaconitine binds to and results in increased activity of CHRNA7 protein] which results in increased transport of Calcium; [Nicotine results in increased activity of CHRNA7 protein] which results in increased transport of Calcium; [PNU-282987 binds to and results in increased activity of CHRNA7 protein] which results in increased uptake of Calcium; Bungarotoxins inhibits the reaction [[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium]; Mecamylamine inhibits the reaction [[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium]; methyllycaconitine inhibits the reaction [[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium]; methyllycaconitine promotes the reaction [[Nicotine results in increased activity of CHRNA7 protein] which results in increased transport of Calcium] CTD PMID:17709503 PMID:21051662 PMID:21715663 NCBI chr 7:63,098,692...63,212,526
Ensembl chr 7:63,098,692...63,212,569
JBrowse link
G Chrnb2 cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) multiple interactions ISO [5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium; alpha-conotoxin MII inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium]; Calcium affects the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased susceptibility to Okadaic Acid]; Dihydro-beta-Erythroidine inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium]; Mecamylamine inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium]
[CHRNA4 protein co-treated with CHRNB2 protein mutant form] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein co-treated with CHRNB2 protein] affects the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein mutant form co-treated with CHRNB2 protein] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine]
CTD PMID:12754307 PMID:21715663 NCBI chr 3:89,753,448...89,764,632
Ensembl chr 3:89,746,195...89,764,632
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 affects expression ISO Calcium affects the expression of CITED2 mRNA CTD PMID:15913539 NCBI chr10:17,723,228...17,725,674
Ensembl chr10:17,723,218...17,725,674
JBrowse link
G Cln8 CLN8 transmembrane ER and ERGIC protein multiple interactions EXP CLN8 protein affects the reaction [[Ionomycin co-treated with Calcium] results in increased transport of D-Aspartic Acid]; CLN8 protein affects the reaction [[Potassium Chloride co-treated with Calcium] results in increased transport of D-Aspartic Acid] CTD PMID:22302580 NCBI chr 8:14,881,335...14,901,720
Ensembl chr 8:14,881,335...14,901,720
JBrowse link
G Cnnm4 cyclin M4 affects expression ISO Calcium affects the expression of CNNM4 mRNA CTD PMID:15913539 NCBI chr 1:36,471,597...36,508,776
Ensembl chr 1:36,471,620...36,508,764
JBrowse link
G Cnr1 cannabinoid receptor 1 (brain) multiple interactions ISO [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein] affects the reaction [Potassium Chloride results in increased transport of Calcium]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] affects the reaction [Potassium Chloride results in increased transport of Calcium]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium results in increased transport of Calcium]; Calcium affects the reaction [Potassium Chloride results in decreased expression of CNR1 mRNA]; Calcium affects the reaction [Potassium Chloride results in decreased expression of CNR1 protein]; CNR1 protein affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; CNR1 protein affects the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Pertussis Toxin inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]] CTD PMID:12421626 PMID:14973253 PMID:16412482 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831
JBrowse link
G Cnr2 cannabinoid receptor 2 (macrophage) multiple interactions ISO CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]; Pertussis Toxin inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]]; SR 144528 inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]] CTD PMID:10617657 NCBI chr 4:135,895,189...135,920,219
Ensembl chr 4:135,895,394...135,920,207
JBrowse link
G Col18a1 collagen, type XVIII, alpha 1 affects abundance EXP COL18A1 protein affects the abundance of Calcium CTD PMID:15296943 NCBI chr10:77,052,178...77,166,530
Ensembl chr10:77,052,178...77,166,548
JBrowse link
G Col1a2 collagen, type I, alpha 2 affects abundance EXP COL1A2 protein affects the abundance of Calcium CTD PMID:10913914 NCBI chr 6:4,505,618...4,541,543
Ensembl chr 6:4,504,814...4,541,544
JBrowse link
G Cp ceruloplasmin affects binding
multiple interactions
ISO Calcium binds to CP protein
[Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of CP protein]
CTD PMID:17242517 PMID:22534743 NCBI chr 3:19,956,933...20,009,750
Ensembl chr 3:19,957,054...20,009,145
JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects expression
multiple interactions
ISO Calcium affects the expression of CREB1 mRNA
[Estradiol results in increased import of Calcium] which results in increased activity of CREB1 protein; Calcium promotes the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased phosphorylation of CREB1 protein]; Calcium promotes the reaction [Dopamine results in increased phosphorylation of CREB1 protein]
CTD PMID:14622123 PMID:15802184 PMID:15913539 NCBI chr 1:64,532,794...64,604,548
Ensembl chr 1:64,532,645...64,604,548
JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 affects expression ISO Calcium affects the expression of CSNK1A1 mRNA CTD PMID:15913539 NCBI chr18:61,554,236...61,590,320
Ensembl chr18:61,555,274...61,590,061
JBrowse link
G Csnk1g3 casein kinase 1, gamma 3 affects expression ISO Calcium affects the expression of CSNK1G3 mRNA CTD PMID:15913539 NCBI chr18:53,862,082...53,955,684
Ensembl chr18:53,862,122...53,955,548
JBrowse link
G Ctnnb1 catenin (cadherin associated protein), beta 1 increases expression
multiple interactions
ISO Calcium results in increased expression of CTNNB1 mRNA; Calcium results in increased expression of CTNNB1 protein
CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]
CTD PMID:24658506 NCBI chr 9:120,933,400...120,960,507
Ensembl chr 9:120,929,216...120,960,507
JBrowse link
G Ctss cathepsin S multiple interactions ISO [CTSS protein results in increased cleavage of and results in decreased activity of CXCL10 protein] which results in decreased uptake of Calcium; [CTSS protein results in increased cleavage of and results in decreased activity of CXCL9 protein] which results in decreased uptake of Calcium; [CTSS protein results in increased cleavage of and results in increased activity of CXCL2 protein] which results in increased uptake of Calcium; [CTSS protein results in increased cleavage of and results in increased activity of CXCL5 protein] which results in increased uptake of Calcium CTD PMID:25833952 NCBI chr 3:95,526,786...95,556,405
Ensembl chr 3:95,526,786...95,556,403
JBrowse link
G Cxcl1 chemokine (C-X-C motif) ligand 1 increases abundance
multiple interactions
ISO CXCL1 protein results in increased abundance of Calcium
epigallocatechin gallate inhibits the reaction [CXCL1 protein results in increased abundance of Calcium]
CTD PMID:9430702 PMID:15237969 NCBI chr 5:90,891,245...90,893,121
Ensembl chr 5:90,891,241...90,893,115
JBrowse link
G Cxcl10 chemokine (C-X-C motif) ligand 10 multiple interactions ISO [CTSS protein results in increased cleavage of and results in decreased activity of CXCL10 protein] which results in decreased uptake of Calcium; [CXCL10 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium CTD PMID:25833952 NCBI chr 5:92,346,638...92,348,889
Ensembl chr 5:92,346,638...92,348,889
JBrowse link
G Cxcl12 chemokine (C-X-C motif) ligand 12 multiple interactions
increases uptake
ISO resveratrol inhibits the reaction [CXCL12 protein affects the localization of Calcium]
CXCL12 protein results in increased uptake of Calcium
CTD PMID:10984371 PMID:11872090 PMID:16212921 NCBI chr 6:117,168,535...117,181,368
Ensembl chr 6:117,168,535...117,181,367
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 multiple interactions
increases uptake
increases abundance
ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[PLA2G1B protein results in increased abundance of Calcium] which results in increased expression of CXCL8 protein]; [CXCL8 protein binds to and results in increased activity of CXCR1 protein] which results in increased abundance of and results in increased activity of Calcium; [CXCL8 protein binds to and results in increased activity of CXCR2 protein] which results in increased abundance of and results in increased activity of Calcium; [PLA2G1B protein results in increased abundance of Calcium] which results in increased expression of CXCL8 protein; Calcium promotes the reaction [Neurotensin results in increased expression of CXCL8 mRNA]; CXCL8 protein affects the localization of and affects the abundance of Calcium; resveratrol inhibits the reaction [CXCL8 protein affects the localization of Calcium]
CXCL8 protein results in increased uptake of Calcium
CXCL8 protein results in increased abundance of Calcium
CTD PMID:10984371 PMID:11298490 PMID:14505796 PMID:15528384 PMID:15748943 More... NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Cxcl2 chemokine (C-X-C motif) ligand 2 multiple interactions ISO [CTSS protein results in increased cleavage of and results in increased activity of CXCL2 protein] which results in increased uptake of Calcium; [CXCL2 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium CTD PMID:25833952 NCBI chr 5:90,903,899...90,905,938
Ensembl chr 5:90,903,871...90,905,938
JBrowse link
G Cxcl9 chemokine (C-X-C motif) ligand 9 multiple interactions
increases abundance
ISO [[CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium] which results in increased expression of EGR1 mRNA; [CTSS protein results in increased cleavage of and results in decreased activity of CXCL9 protein] which results in decreased uptake of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium
CXCL9 protein results in increased abundance of Calcium
CTD PMID:12517959 PMID:25833952 NCBI chr 5:92,321,331...92,328,079
Ensembl chr 5:92,321,347...92,328,079
JBrowse link
G Cxcr1 chemokine (C-X-C motif) receptor 1 multiple interactions
affects abundance
ISO [CXCL8 protein binds to and results in increased activity of CXCR1 protein] which results in increased abundance of and results in increased activity of Calcium
CXCR1 protein affects the abundance of Calcium
CTD PMID:11298490 PMID:12055238 NCBI chr 1:74,191,785...74,194,708
Ensembl chr 1:74,191,785...74,194,631
JBrowse link
G Cxcr2 chemokine (C-X-C motif) receptor 2 affects transport
multiple interactions
ISO
EXP
CXCR2 protein affects the transport of Calcium
[CXCL2 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium; [CXCL5 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium; [CXCL8 protein binds to and results in increased activity of CXCR2 protein] which results in increased abundance of and results in increased activity of Calcium
Excitatory Amino Acid Agonists inhibits the reaction [CXCR2 protein affects the localization of Calcium]
CTD PMID:11298490 PMID:15618463 PMID:15914698 PMID:25833952 NCBI chr 1:74,153,994...74,161,246
Ensembl chr 1:74,153,989...74,161,246
JBrowse link
G Cxcr3 chemokine (C-X-C motif) receptor 3 affects abundance
multiple interactions
ISO CXCR3 protein affects the abundance of Calcium
[[CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium] which results in increased expression of EGR1 mRNA; [CXCL10 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium
CTD PMID:12055238 PMID:12517959 PMID:25833952 NCBI chr  X:101,731,535...101,734,147
Ensembl chr  X:101,731,535...101,734,269
JBrowse link
G Cxcr4 chemokine (C-X-C motif) receptor 4 affects abundance ISO CXCR4 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr 1:128,588,199...128,592,299
Ensembl chr 1:128,588,199...128,592,293
JBrowse link
G Cxcr5 chemokine (C-X-C motif) receptor 5 affects abundance ISO CXCR5 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr 9:44,511,787...44,526,444
Ensembl chr 9:44,511,787...44,561,877
JBrowse link
G Cycs cytochrome c, somatic multiple interactions
increases secretion
decreases secretion
ISO [Calcium co-treated with Phosphates] affects the localization of CYCS protein; caffeic acid phenethyl ester inhibits the reaction [Calcium results in increased secretion of CYCS protein]; Cyclosporine inhibits the reaction [[Calcium co-treated with Phosphates] affects the localization of CYCS protein]; Nicotine inhibits the reaction [[Calcium co-treated with Phosphates] affects the localization of CYCS protein]; xestospongin C inhibits the reaction [Calcium results in decreased secretion of CYCS protein] CTD PMID:15345483 PMID:15469948 PMID:15985439 NCBI chr 6:50,562,563...50,566,569
Ensembl chr 6:50,562,563...50,566,538
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO 2-aminoethoxydiphenyl borate inhibits the reaction [[oltipraz results in increased abundance of Calcium] which results in increased expression of CYP1A1 mRNA]; [2,3,7,8-tetrachlorodibenzofuran co-treated with Calcium] results in increased expression of CYP1A1 mRNA; [oltipraz results in increased abundance of Calcium] which results in increased expression of CYP1A1 mRNA; Calcium promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; Calcium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]
CTD PMID:1979076 PMID:11959854 PMID:16237193 PMID:23298284 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO
EXP
Calcium promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; Calcium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
CTD PMID:16237193 PMID:19782052 NCBI chr17:79,706,940...79,715,061
Ensembl chr17:79,701,537...79,715,061
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 affects expression
multiple interactions
ISO Calcium affects the expression of CYP24A1 mRNA
[Calcium co-treated with Calcitriol] affects the expression of CYP24A1 mRNA
CTD PMID:15913539 NCBI chr 2:170,482,957...170,497,145
Ensembl chr 2:170,482,708...170,497,145
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 affects expression ISO Calcium affects the expression of CYP27B1 mRNA CTD PMID:15913539 NCBI chr10:127,048,246...127,054,884
Ensembl chr10:127,048,250...127,053,006
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects expression
decreases uptake
ISO Calcium affects the expression of CYP2E1 mRNA
CYP2E1 protein results in decreased uptake of Calcium
CTD PMID:15913539 PMID:19028543 NCBI chr 7:140,763,819...140,774,990
Ensembl chr 7:140,763,739...140,774,987
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 multiple interactions ISO
EXP
[CP 199330 binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; [CP 199331 binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; [CP 265298 binds to and results in decreased activity of CYSLTR1 protein] which results in decreased abundance of Calcium; [CP 288886 binds to and results in decreased activity of CYSLTR1 protein] which results in decreased abundance of Calcium; [Leukotriene C4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [Leukotriene D4 results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [Leukotriene E4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [pranlukast binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; [Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [zafirlukast binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; BAY u9773 inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; CYSLTR1 protein promotes the reaction [Leukotriene D4 results in increased abundance of Calcium]; montelukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; montelukast inhibits the reaction [[Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; pobilukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; pranlukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; verlukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; zafirlukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; zafirlukast inhibits the reaction [[Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; zafirlukast inhibits the reaction [CYSLTR1 protein promotes the reaction [Leukotriene D4 results in increased abundance of Calcium]] CTD PMID:8014876 PMID:9934474 PMID:10391245 PMID:10462554 PMID:10509933 More... NCBI chr  X:106,576,509...106,603,679
Ensembl chr  X:106,574,346...106,603,679
JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 multiple interactions ISO [Leukotriene C4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene C4 results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene D4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene D4 results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene E4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene E4 results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; BAY u9773 inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium] CTD PMID:10851239 PMID:11093801 NCBI chr14:73,025,672...73,049,114
Ensembl chr14:73,025,603...73,049,114
JBrowse link
G Ddr1 discoidin domain receptor family, member 1 affects expression ISO Calcium affects the expression of DDR1 mRNA CTD PMID:15913539 NCBI chr17:35,681,567...35,704,741
Ensembl chr17:35,681,567...35,704,621
JBrowse link
G Dmd dystrophin, muscular dystrophy increases abundance
multiple interactions
EXP DMD gene mutant form results in increased abundance of Calcium
Nifedipine inhibits the reaction [DMD gene mutant form results in increased abundance of Calcium]
CTD PMID:24349043 NCBI chr  X:82,814,664...85,205,050
Ensembl chr  X:82,948,870...85,206,141
JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 multiple interactions
decreases transport
ISO [DNAJB11 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [DNAJB11 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin; DNAJB11 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium] CTD PMID:26085089 NCBI chr16:22,857,845...22,879,634
Ensembl chr16:22,857,845...22,879,634
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 multiple interactions
decreases transport
ISO [DNAJC3 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [DNAJC3 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin; DNAJC3 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium] CTD PMID:26085089 NCBI chr14:118,937,932...118,981,702
Ensembl chr14:118,937,976...118,981,697
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions ISO [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased activity of DRD1 protein] which results in increased abundance of Calcium CTD PMID:14622123 NCBI chr13:54,051,183...54,055,658
Ensembl chr13:54,051,183...54,055,705
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions ISO [Norepinephrine binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium; [Quinpirole binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium; Sulpiride inhibits the reaction [[Norepinephrine binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium]; Sulpiride inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium]
[DRD2 protein affects the abundance of Calcium] which results in decreased transport of Barium
CTD PMID:8032591 PMID:11124974 NCBI chr 9:49,340,360...49,408,177
Ensembl chr 9:49,340,627...49,408,177
JBrowse link
G Drd3 dopamine receptor D3 increases phosphorylation ISO Calcium results in increased phosphorylation of DRD3 protein CTD PMID:19217379 NCBI chr16:43,754,015...43,825,982
Ensembl chr16:43,754,026...43,822,932
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions ISO Calcium affects the reaction [Potassium Chloride results in increased expression of DUSP1 mRNA] CTD PMID:11577072 NCBI chr17:26,505,591...26,508,472
Ensembl chr17:26,505,590...26,562,128
JBrowse link
G Edn1 endothelin 1 affects transport
increases abundance
affects localization
multiple interactions
increases uptake
ISO
EXP
EDN1 protein affects the transport of Calcium
EDN1 protein results in increased abundance of Calcium
EDN1 protein affects the localization of Calcium
Carvedilol inhibits the reaction [EDN1 protein results in increased import of and results in increased abundance of Calcium]; EDN1 protein affects the abundance of and affects the localization of Calcium; EDN1 protein results in increased import of and results in increased abundance of Calcium; Glucose affects the reaction [EDN1 protein affects the abundance of and affects the localization of Calcium]; Heparin inhibits the reaction [EDN1 protein results in increased abundance of Calcium]
EDN1 protein results in increased uptake of Calcium
EDN1 protein affects the localization of and affects the abundance of Calcium
EDN1 protein results in increased transport of and results in increased abundance of Calcium; Propofol inhibits the reaction [EDN1 protein affects the transport of Calcium]
CTD PMID:1443220 PMID:9138053 PMID:11425647 PMID:12628492 PMID:12821678 More... NCBI chr13:42,301,476...42,307,990
Ensembl chr13:42,301,476...42,307,990
JBrowse link
G Edn2 endothelin 2 increases uptake
multiple interactions
EXP EDN2 protein results in increased uptake of Calcium
EDN2 protein affects the localization of and affects the abundance of Calcium
CTD PMID:11425647 NCBI chr 4:120,161,206...120,167,360
Ensembl chr 4:120,161,206...120,167,360
JBrowse link
G Edn3 endothelin 3 multiple interactions
increases uptake
EXP
ISO
EDN3 protein affects the localization of and affects the abundance of Calcium
BQ 788 inhibits the reaction [EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium]]; EDN3 protein inhibits the reaction [APP protein results in increased uptake of Calcium]; EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium]
EDN3 protein results in increased uptake of Calcium
CTD PMID:11425647 PMID:12383957 PMID:15695168 NCBI chr 2:174,760,619...174,784,042
Ensembl chr 2:174,760,619...174,784,042
JBrowse link
G Ednra endothelin receptor type A affects activity ISO Calcium affects the activity of EDNRA protein CTD PMID:12628492 NCBI chr 8:77,663,029...77,724,452
Ensembl chr 8:77,663,031...77,724,464
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of EEF2 mRNA CTD PMID:15913539 NCBI chr10:81,176,631...81,182,509
Ensembl chr10:81,176,631...81,182,498
JBrowse link
G Egf epidermal growth factor increases abundance
multiple interactions
affects expression
increases transport
ISO
EXP
EGF protein results in increased abundance of Calcium
[Calcium co-treated with Calcitriol] affects the expression of EGF mRNA
Calcium affects the expression of EGF mRNA
EGF protein results in increased transport of Calcium
[IGF2 protein co-treated with EGF protein] results in increased import of Calcium
RTKI cpd inhibits the reaction [EGF protein results in increased abundance of Calcium]
CTD PMID:2442157 PMID:11527950 PMID:15913539 PMID:24990931 NCBI chr 3:129,677,574...129,755,322
Ensembl chr 3:129,677,565...129,755,316
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO Calcium affects the phosphorylation of and affects the expression of EGFR protein CTD PMID:8393775 NCBI chr11:16,752,203...16,913,907
Ensembl chr11:16,752,203...16,918,158
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO [[CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium] which results in increased expression of EGR1 mRNA; [Ionomycin results in increased abundance of Calcium] which results in increased expression of EGR1 protein CTD PMID:12517959 NCBI chr18:34,861,207...34,864,956
Ensembl chr18:34,859,823...34,864,984
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions ISO Calcium promotes the reaction [Diclofenac results in increased phosphorylation of EIF2AK3 protein] CTD PMID:26609140 NCBI chr 6:70,844,484...70,905,241
Ensembl chr 6:70,844,515...70,905,245
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of EIF4A2 mRNA CTD PMID:15913539 NCBI chr16:23,107,468...23,114,132
Ensembl chr16:23,107,444...23,114,136
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:12935885 NCBI chr 8:27,260,327...27,275,656
Ensembl chr 8:27,260,329...27,276,674
JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic affects expression ISO Calcium affects the expression of EPHX2 mRNA CTD PMID:15913539 NCBI chr14:66,084,372...66,124,522
Ensembl chr14:66,084,374...66,124,500
JBrowse link
G F2 coagulation factor II increases abundance
increases localization
multiple interactions
increases uptake
ISO F2 protein results in increased abundance of Calcium
F2 protein results in increased localization of Calcium
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [F2 protein results in increased localization of Calcium]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [F2 protein results in increased localization of Calcium]; Apigenin inhibits the reaction [F2 protein results in increased localization of Calcium]; arsenite inhibits the reaction [F2 protein results in increased abundance of Calcium]; Genistein inhibits the reaction [F2 protein results in increased localization of Calcium]; Nickel inhibits the reaction [F2 protein results in increased uptake of Calcium]; Quercetin inhibits the reaction [F2 protein results in increased localization of Calcium]
CTD PMID:2125206 PMID:19814731 PMID:22244921 NCBI chr 2:91,612,397...91,636,457
Ensembl chr 2:91,625,320...91,636,414
JBrowse link
G F2r coagulation factor II (thrombin) receptor multiple interactions EXP [Peptides results in increased activity of F2R protein] which results in increased abundance of Calcium CTD PMID:15086339 NCBI chr13:95,601,780...95,618,466
Ensembl chr13:95,601,803...95,618,487
JBrowse link
G F2rl1 coagulation factor II (thrombin) receptor-like 1 multiple interactions ISO F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]; PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]] CTD PMID:16793902 NCBI chr13:95,511,718...95,525,240
Ensembl chr13:95,511,732...95,525,227
JBrowse link
G F2rl3 coagulation factor II (thrombin) receptor-like 3 multiple interactions ISO
EXP
[alanyl-tyrosyl-prolyl-glycyl-lysyl-phenylalanine binds to and results in increased activity of F2RL3 protein] which results in increased uptake of Calcium
F2RL3 protein affects the localization of and affects the transport of Calcium
CTD PMID:16702038 PMID:17707436 NCBI chr 8:72,761,659...72,763,898
Ensembl chr 8:72,761,880...72,763,874
JBrowse link
G F8 coagulation factor VIII multiple interactions ISO [Copper co-treated with Calcium] results in increased activity of [F8 protein alternative form binds to F8 protein alternative form]; Calcium results in increased activity of [F8 protein alternative form binds to F8 protein alternative form] CTD PMID:11513607 NCBI chr  X:75,170,344...75,382,738
Ensembl chr  X:75,172,715...75,382,615
JBrowse link
G Fasl Fas ligand (TNF superfamily, member 6) multiple interactions
affects localization
EXP bafilomycin A1 inhibits the reaction [FASL protein affects the localization of Calcium]; CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]; CD38 protein inhibits the reaction [CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]]; Ryanodine inhibits the reaction [FASL protein affects the localization of Calcium] CTD PMID:20200208 NCBI chr 1:161,780,691...161,788,495
Ensembl chr 1:161,780,689...161,788,495
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression ISO Calcium results in increased expression of FGF1 protein CTD PMID:15264218 NCBI chr18:38,838,672...38,929,470
Ensembl chr18:38,838,673...38,929,472
JBrowse link
G Fgf23 fibroblast growth factor 23 affects expression ISO Calcium affects the expression of FGF23 mRNA; Calcium affects the expression of FGF23 protein CTD PMID:15086938 PMID:16381997 NCBI chr 6:127,072,902...127,082,296
Ensembl chr 6:127,072,902...127,081,408
JBrowse link
G Fgf9 fibroblast growth factor 9 affects expression ISO Calcium affects the expression of FGF9 mRNA CTD PMID:15913539 NCBI chr14:58,070,671...58,112,854
Ensembl chr14:58,070,547...58,112,720
JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of FGFR1 mRNA CTD PMID:15913539 NCBI chr 8:25,518,759...25,575,718
Ensembl chr 8:25,513,654...25,575,718
JBrowse link
G Fis1 fission, mitochondrial 1 affects expression ISO Calcium affects the expression of FIS1 mRNA CTD PMID:15913539 NCBI chr 5:136,953,275...136,966,234
Ensembl chr 5:136,953,275...136,966,234
JBrowse link
G Fkbp1a FK506 binding protein 1a multiple interactions ISO FKBP1A protein inhibits the reaction [Calcium results in increased activity of RYR2 protein] CTD PMID:17872463 NCBI chr 2:151,542,483...151,561,691
Ensembl chr 2:151,542,483...151,561,692
JBrowse link
G Fkbp1b FK506 binding protein 1b multiple interactions EXP FKBP1B gene mutant form inhibits the reaction [Acetylcholine affects the localization of and affects the abundance of Calcium]; Ryanodine inhibits the reaction [FKBP1B gene mutant form inhibits the reaction [Acetylcholine affects the localization of and affects the abundance of Calcium]] CTD PMID:17261647 NCBI chr12:4,833,176...4,841,573
Ensembl chr12:4,833,174...4,841,591
JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) affects expression ISO Calcium affects the expression of FURIN mRNA CTD PMID:15913539 NCBI chr 7:80,389,194...80,405,441
Ensembl chr 7:80,388,585...80,405,436
JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 multiple interactions
decreases activity
ISO Calcium inhibits the reaction [FXYD2 protein results in increased transport of Deoxyglucose]; Calcium inhibits the reaction [FXYD2 protein results in increased transport of Inulin]
Calcium results in decreased activity of FXYD2 protein
CTD PMID:11533133 NCBI chr 9:45,399,709...45,410,278
Ensembl chr 9:45,399,669...45,410,278
JBrowse link
G G6pc glucose-6-phosphatase, catalytic affects expression ISO Calcium affects the expression of G6PC1 mRNA CTD PMID:15913539 NCBI chr11:101,367,716...101,377,903
Ensembl chr11:101,367,561...101,377,903
JBrowse link
G Gabbr1 gamma-aminobutyric acid (GABA) B receptor, 1 multiple interactions
affects expression
ISO Calcium promotes the reaction [3-aminopropylphosphinic acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]; Calcium promotes the reaction [CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]]; Calcium promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]
Calcium affects the expression of GABBR1 mRNA
CTD PMID:15627515 PMID:15913539 NCBI chr17:37,045,966...37,074,305
Ensembl chr17:37,045,966...37,075,067
JBrowse link
G Gabbr2 gamma-aminobutyric acid (GABA) B receptor, 2 multiple interactions ISO Calcium promotes the reaction [3-aminopropylphosphinic acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]; Calcium promotes the reaction [CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]]; Calcium promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]] CTD PMID:15627515 NCBI chr 4:46,662,318...46,991,714
Ensembl chr 4:46,662,305...46,991,873
JBrowse link
G Gast gastrin multiple interactions ISO Calcium promotes the reaction [Colforsin results in increased secretion of GAST protein]; Calcium promotes the reaction [Terbutaline results in increased secretion of GAST protein] CTD PMID:9277405 NCBI chr11:100,334,407...100,336,997
Ensembl chr11:100,334,407...100,336,996
JBrowse link
G Gata1 GATA binding protein 1 affects expression ISO Calcium affects the expression of GATA1 mRNA CTD PMID:15913539 NCBI chr  X:7,959,260...7,976,663
Ensembl chr  X:7,959,260...7,978,071
JBrowse link
G Gc vitamin D binding protein affects expression ISO Calcium affects the expression of GC mRNA CTD PMID:15913539 NCBI chr 5:89,417,511...89,457,898
Ensembl chr 5:89,417,522...89,457,898
JBrowse link
G Gcg glucagon multiple interactions ISO Calcium affects the reaction [Pyruvic Acid results in increased secretion of GCG protein] CTD PMID:15919803 NCBI chr 2:62,474,530...62,483,653
Ensembl chr 2:62,474,530...62,483,650
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of GCLC mRNA CTD PMID:15913539 NCBI chr 9:77,754,535...77,794,489
Ensembl chr 9:77,754,535...77,794,485
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]; Calcium deficiency inhibits the reaction [Ethanol results in increased expression of GFAP protein] CTD PMID:17888892 PMID:21879721 NCBI chr11:102,887,336...102,897,200
Ensembl chr11:102,887,336...102,900,912
JBrowse link
G Ghr growth hormone receptor affects expression
multiple interactions
ISO Calcium affects the expression of GHR mRNA
[Calcium co-treated with Calcitriol] affects the expression of GHR mRNA
CTD PMID:15913539 NCBI chr15:3,317,755...3,583,352
Ensembl chr15:3,317,760...3,583,492
JBrowse link
G Gipc3 GIPC PDZ domain containing family, member 3 affects uptake EXP GIPC3 protein affects the uptake of Calcium CTD PMID:27462107 NCBI chr10:81,335,262...81,343,620
Ensembl chr10:81,335,265...81,343,266
JBrowse link
G Glrx3 glutaredoxin 3 affects response to substance ISO GLRX3 protein affects the susceptibility to Calcium CTD PMID:16809552 NCBI chr 7:137,437,573...137,469,631
Ensembl chr 7:137,437,614...137,468,594
JBrowse link
G Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 affects expression ISO Calcium affects the expression of GNAI2 mRNA CTD PMID:15913539 NCBI chr 9:107,614,125...107,635,391
Ensembl chr 9:107,614,125...107,635,367
JBrowse link
G Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus multiple interactions EXP [[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium; [[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium CTD PMID:23022524 NCBI chr 2:174,284,320...174,346,744
Ensembl chr 2:174,284,320...174,346,744
JBrowse link
G Gpbar1 G protein-coupled bile acid receptor 1 multiple interactions ISO
EXP
[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased abundance of Calcium
[[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium; [[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium
CTD PMID:23022524 NCBI chr 1:74,278,600...74,279,589
Ensembl chr 1:74,278,550...74,279,624
JBrowse link
G Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) multiple interactions ISO Calcium deficiency inhibits the reaction [Excitatory Amino Acid Agonists results in decreased phosphorylation of GRIA1 protein] CTD PMID:28404816 NCBI chr11:57,011,571...57,330,244
Ensembl chr11:57,011,387...57,330,244
JBrowse link
G Gria2 glutamate receptor, ionotropic, AMPA2 (alpha 2) multiple interactions ISO Calcium promotes the reaction [PICK1 protein binds to GRIA2 protein] CTD PMID:28404816 NCBI chr 3:80,681,450...80,804,227
Ensembl chr 3:80,681,450...80,802,835
JBrowse link
G Grm1 glutamate receptor, metabotropic 1 multiple interactions ISO 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]; [3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium; Flufenamic Acid inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]; GRM1 protein promotes the reaction [Propionates results in increased transport of Calcium]; Ruthenium Red inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium] CTD PMID:14622174 PMID:24582715 NCBI chr10:10,686,059...11,082,382
Ensembl chr10:10,686,059...11,082,356
JBrowse link
G Gsr glutathione reductase multiple interactions ISO [Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in decreased activity of GSR protein]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in decreased activity of GSR protein]; [Carmustine results in decreased activity of GSR protein] which results in increased uptake of Calcium; Calcium affects the reaction [sodium arsenite results in decreased activity of GSR protein] CTD PMID:15321730 PMID:24184500 NCBI chr 8:33,653,238...33,698,162
Ensembl chr 8:33,652,523...33,698,163
JBrowse link
G Hc hemolytic complement multiple interactions ISO
EXP
[C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium; resveratrol inhibits the reaction [[C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium] CTD PMID:19284563 PMID:19346296 NCBI chr 2:34,983,329...35,068,506
Ensembl chr 2:34,983,331...35,061,438
JBrowse link
G Hcar2 hydroxycarboxylic acid receptor 2 increases abundance
multiple interactions
ISO HCAR3 protein results in increased abundance of Calcium
Pertussis Toxin affects the reaction [HCAR3 protein results in increased abundance of Calcium]
CTD PMID:19237584 NCBI chr 5:123,863,570...123,865,516
Ensembl chr 5:123,863,570...123,865,499
JBrowse link
G Hectd4 HECT domain E3 ubiquitin protein ligase 4 multiple interactions ISO Calcium affects the reaction [HECTD4 gene SNP affects the abundance of Lead] CTD PMID:28212632 NCBI chr 5:121,219,513...121,368,577
Ensembl chr 5:121,220,219...121,368,577
JBrowse link
G Hes1 hes family bHLH transcription factor 1 affects expression ISO Calcium affects the expression of HES1 mRNA CTD PMID:15913539 NCBI chr16:30,065,357...30,067,796
Ensembl chr16:30,064,384...30,067,796
JBrowse link
G Hgf hepatocyte growth factor increases abundance ISO HGF protein results in increased abundance of Calcium CTD PMID:10963052 NCBI chr 5:16,553,495...16,619,439
Ensembl chr 5:16,553,495...16,620,152
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 affects expression ISO Calcium affects the expression of HMGCS2 mRNA CTD PMID:15913539 NCBI chr 3:98,280,431...98,310,738
Ensembl chr 3:98,280,435...98,310,738
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO Calcium affects the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA] CTD PMID:21443188 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hnf4a hepatic nuclear factor 4, alpha affects expression ISO Calcium affects the expression of HNF4A mRNA CTD PMID:15913539 NCBI chr 2:163,506,811...163,572,907
Ensembl chr 2:163,506,808...163,572,910
JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D multiple interactions ISO Calcium deficiency promotes the reaction [HNRNPD protein binds to PTH 3' UTR] CTD PMID:18583400 NCBI chr 5:99,955,935...99,979,130
Ensembl chr 5:99,955,935...99,978,938
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U affects expression ISO Calcium affects the expression of SP120 mRNA CTD PMID:15913539 NCBI chr 1:178,321,108...178,338,891
Ensembl chr 1:178,321,108...178,337,797
JBrowse link
G Homer1 homer scaffolding protein 1 multiple interactions ISO HOMER1 protein alternative form inhibits the reaction [Caffeine promotes the reaction [RYR2 protein results in increased secretion of Calcium]]; HOMER1 protein alternative form inhibits the reaction [Cyclic ADP-Ribose promotes the reaction [RYR2 protein results in increased secretion of Calcium]] CTD PMID:12887973 NCBI chr13:93,303,757...93,405,129
Ensembl chr13:93,299,635...93,405,129
JBrowse link
G Hpca hippocalcin decreases response to substance EXP HPCA protein results in decreased susceptibility to Calcium CTD PMID:12445469 NCBI chr 4:129,111,570...129,125,919
Ensembl chr 4:129,111,570...129,122,036
JBrowse link
G Hrh1 histamine receptor H1 multiple interactions
increases abundance
ISO [6-((2-(4-imidazolyl)ethyl)amino)heptanoic acid 4-toluidide binds to and results in increased activity of HRH1 protein] which results in increased abundance of Calcium; [Histamine results in increased activity of HRH1 protein] which results in increased abundance of Calcium; [HRH1 protein binds to Histamine] which results in increased import of Calcium; [HRH1 protein binds to Lidocaine] which results in increased import of Calcium; [HRH1 protein binds to Procaine] which results in increased import of Calcium; [HRH1 protein binds to Tetracaine] which results in increased import of Calcium; fexofenadine inhibits the reaction [[Histamine binds to and results in increased activity of HRH1 protein] which results in increased abundance of Calcium]; HRH1 protein promotes the reaction [Histamine results in increased export of Calcium]; Triprolidine inhibits the reaction [[Histamine results in increased activity of HRH1 protein] which results in increased abundance of Calcium]; Triprolidine inhibits the reaction [HRH1 protein promotes the reaction [Histamine results in increased export of Calcium]]
HRH1 protein results in increased abundance of Calcium
CTD PMID:2419744 PMID:11238657 PMID:11527950 PMID:19443731 PMID:32061592 NCBI chr 6:114,397,936...114,483,298
Ensembl chr 6:114,397,936...114,483,296
JBrowse link
G Hrh3 histamine receptor H3 multiple interactions EXP [4-(1H-imidazol-4-ylmethyl)piperidine binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; [Histamine binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; [imetit binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; [Methylhistamines binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; clobenpropit inhibits the reaction [[Methylhistamines binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium] CTD PMID:12706455 NCBI chr 2:180,099,465...180,104,484
Ensembl chr 2:180,099,465...180,104,488
JBrowse link
G Hrh4 histamine receptor H4 multiple interactions ISO 1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine inhibits the reaction [[4-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium]; 1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine inhibits the reaction [[clobenpropit binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium]; [4-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [alpha-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [clobenpropit binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [Histamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [imetit binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [N-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium CTD PMID:11181941 PMID:17507084 NCBI chr18:13,006,982...13,023,701
Ensembl chr18:13,006,990...13,022,882
JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of HSD17B12 mRNA CTD PMID:15913539 NCBI chr 2:94,032,697...94,157,909
Ensembl chr 2:94,032,689...94,157,964
JBrowse link
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 multiple interactions EXP Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]] CTD PMID:23184943 NCBI chr12:110,691,036...110,696,395
Ensembl chr12:110,690,605...110,702,728
JBrowse link
G Hspa5 heat shock protein 5 multiple interactions
decreases transport
ISO [DNAJB11 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [DNAJC3 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [HSPA5 protein binds to SEC61A1 protein] which results in decreased transport of Calcium; [HSPA5 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin CTD PMID:26085089 NCBI chr 2:34,772,090...34,776,529
Ensembl chr 2:34,771,970...34,777,547
JBrowse link
G Htr1a 5-hydroxytryptamine (serotonin) receptor 1A increases activity ISO Calcium results in increased activity of HTR1A protein CTD PMID:11356925 NCBI chr13:105,443,693...105,448,133
Ensembl chr13:105,443,639...105,448,122
JBrowse link
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A multiple interactions ISO HTR2A protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium] CTD PMID:16901936 NCBI chr14:74,640,874...74,706,859
Ensembl chr14:74,640,840...74,709,494
JBrowse link
G Htr2b 5-hydroxytryptamine (serotonin) receptor 2B multiple interactions EXP Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK1 protein]; Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK3 protein] CTD PMID:18758753 NCBI chr 1:86,097,546...86,116,231
Ensembl chr 1:86,099,026...86,111,970
JBrowse link
G Htr7 5-hydroxytryptamine (serotonin) receptor 7 multiple interactions ISO HTR7 protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium] CTD PMID:16901936 NCBI chr19:35,958,415...36,058,133
Ensembl chr19:35,958,734...36,057,507
JBrowse link
G Ifng interferon gamma multiple interactions EXP
ISO
KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]]
[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]; [TNF protein co-treated with IFNG protein] promotes the reaction [Diclofenac affects the abundance of Calcium]; Calcium promotes the reaction [[Diclofenac co-treated with IFNG protein] results in increased phosphorylation of STAT1 protein]
CTD PMID:23747339 PMID:26609140 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Ift88 intraflagellar transport 88 multiple interactions
increases uptake
EXP Gadolinium inhibits the reaction [IFT88 protein mutant form results in increased uptake of Calcium]; IFT88 protein affects the reaction [PKD2 protein results in increased uptake of Calcium] CTD PMID:16396941 NCBI chr14:57,424,064...57,517,936
Ensembl chr14:57,424,062...57,517,936
JBrowse link
G Igf1 insulin-like growth factor 1 affects expression
multiple interactions
increases import
ISO
EXP
Calcium affects the expression of IGF1 mRNA
Cobalt inhibits the reaction [IGF1 protein results in increased import of Calcium]; tetramethrin inhibits the reaction [IGF1 protein results in increased import of Calcium]
CTD PMID:1550224 PMID:2460452 PMID:2539779 PMID:15913539 NCBI chr10:87,858,265...87,937,047
Ensembl chr10:87,858,265...87,937,042
JBrowse link
G Igf2 insulin-like growth factor 2 multiple interactions
increases import
EXP [IGF2 protein co-treated with EGF protein] results in increased import of Calcium; Cobalt inhibits the reaction [IGF2 protein results in increased import of Calcium]; Lanthanum inhibits the reaction [IGF2 protein results in increased import of Calcium]; Pertussis Toxin inhibits the reaction [IGF2 protein results in increased import of Calcium]; tetramethrin inhibits the reaction [IGF2 protein results in increased import of Calcium] CTD PMID:2442157 PMID:2460452 PMID:2539779 NCBI chr 7:142,650,768...142,666,816
Ensembl chr 7:142,650,766...142,666,816
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 affects expression ISO Calcium affects the expression of IGFBP2 mRNA CTD PMID:15913539 NCBI chr 1:72,824,480...72,852,474
Ensembl chr 1:72,824,503...72,852,474
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 affects expression
decreases degradation
ISO Calcium affects the expression of IGFBP5 mRNA
Calcium results in decreased degradation of IGFBP5 protein
CTD PMID:8894652 PMID:15913539 NCBI chr 1:72,858,065...72,874,865
Ensembl chr 1:72,857,932...72,874,884
JBrowse link
G Il11 interleukin 11 multiple interactions
increases abundance
EXP Flurbiprofen inhibits the reaction [IL11 protein results in increased abundance of Calcium]; IL13 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium]; IL4 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium]; IL6ST protein promotes the reaction [IL11 protein results in increased abundance of Calcium]; Indomethacin inhibits the reaction [IL11 protein results in increased abundance of Calcium]; TNFRSF11B protein inhibits the reaction [IL11 protein results in increased abundance of Calcium] CTD PMID:12110441 NCBI chr 7:4,772,373...4,782,907
Ensembl chr 7:4,772,373...4,782,859
JBrowse link
G Il13 interleukin 13 multiple interactions EXP IL13 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium] CTD PMID:12110441 NCBI chr11:53,631,323...53,634,702
Ensembl chr11:53,631,324...53,634,702
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]] CTD PMID:23747339 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il4 interleukin 4 multiple interactions EXP IL4 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium] CTD PMID:12110441 NCBI chr11:53,612,460...53,618,665
Ensembl chr11:53,602,982...53,618,669
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO Calcimycin inhibits the reaction [Calcium promotes the reaction [Histamine results in increased expression of IL6 protein]]; Calcium promotes the reaction [Histamine results in increased expression of IL6 protein]; Edetic Acid inhibits the reaction [Calcium promotes the reaction [Histamine results in increased expression of IL6 protein]]
Calcium results in increased expression of IL6 mRNA
CTD PMID:11238657 PMID:20682585 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Il6st interleukin 6 signal transducer multiple interactions EXP IL6ST protein promotes the reaction [IL11 protein results in increased abundance of Calcium] CTD PMID:12110441 NCBI chr13:112,464,070...112,506,860
Ensembl chr13:112,464,070...112,510,086
JBrowse link
G Ilf3 interleukin enhancer binding factor 3 multiple interactions ISO Calcium affects the reaction [Vanadates results in increased activity of ILF3 protein] CTD PMID:10623810 NCBI chr 9:21,367,731...21,405,363
Ensembl chr 9:21,367,871...21,405,361
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 multiple interactions EXP Calcium promotes the reaction [PAFAH1B1 protein binds to IQGAP1 protein binds to CDC42 protein] CTD PMID:16369480 NCBI chr 7:80,711,583...80,815,549
Ensembl chr 7:80,711,583...80,825,974
JBrowse link
G Itga2 integrin alpha 2 multiple interactions EXP ITGA2 protein promotes the reaction [[Dinoprostone co-treated with Serotonin] results in increased import of Calcium]; TRPV4 protein promotes the reaction [ITGA2 protein promotes the reaction [[Dinoprostone co-treated with Serotonin] results in increased import of Calcium]] CTD PMID:18234883 NCBI chr13:114,833,081...114,932,100
Ensembl chr13:114,833,081...114,932,100
JBrowse link
G Itgb1bp2 integrin beta 1 binding protein 2 multiple interactions ISO
EXP
Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to SUGT1 protein]]
Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]]
CTD PMID:23184943 NCBI chr  X:101,449,088...101,466,122
Ensembl chr  X:101,449,088...101,453,541
JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 multiple interactions ISO Calcium promotes the reaction [ITIH1 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr14:30,929,180...30,943,289
Ensembl chr14:30,929,180...30,943,289
JBrowse link
G Itih2 inter-alpha trypsin inhibitor, heavy chain 2 multiple interactions ISO Calcium promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr 2:10,094,591...10,130,683
Ensembl chr 2:10,094,593...10,131,396
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor 1 multiple interactions ISO ITPR1 protein promotes the reaction [Acetaldehyde metabolite results in increased abundance of Calcium]; ITPR1 protein promotes the reaction [Ethanol metabolite results in increased abundance of Calcium] CTD PMID:17241155 NCBI chr 6:108,213,083...108,551,116
Ensembl chr 6:108,213,096...108,551,109
JBrowse link
G Itpr2 inositol 1,4,5-triphosphate receptor 2 multiple interactions EXP 2-aminoethoxydiphenyl borate inhibits the reaction [[adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium]; [adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium; xestospongin C inhibits the reaction [[adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium] CTD PMID:15201137 NCBI chr 6:146,108,299...146,502,258
Ensembl chr 6:146,108,299...146,502,223
JBrowse link
G Itpr3 inositol 1,4,5-triphosphate receptor 3 affects expression ISO Calcium affects the expression of ITPR3 protein CTD PMID:10963052 NCBI chr17:27,057,002...27,122,223
Ensembl chr17:27,057,304...27,122,223
JBrowse link
G Ivl involucrin increases expression
multiple interactions
ISO Calcium results in increased expression of IVL mRNA
NPS R-467 promotes the reaction [Calcium results in increased expression of IVL mRNA]
CTD PMID:10469331 NCBI chr 3:92,570,899...92,573,790
Ensembl chr 3:92,570,902...92,573,735
JBrowse link
G Jak2 Janus kinase 2 multiple interactions EXP JAK2 protein promotes the reaction [LEP protein results in increased transport of Calcium] CTD PMID:20107083 NCBI chr19:29,251,803...29,313,095
Ensembl chr19:29,251,828...29,313,080
JBrowse link
G Kcne1 potassium voltage-gated channel, Isk-related subfamily, member 1 increases activity
multiple interactions
EXP Calcium results in increased activity of KCNE1 protein
W 7 inhibits the reaction [Calcium results in increased activity of KCNE1 protein]
CTD PMID:1655403 NCBI chr16:92,346,001...92,359,468
Ensembl chr16:92,345,982...92,359,468
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 multiple interactions ISO Nimodipine inhibits the reaction [KCNH2 protein affects the abundance of Calcium] CTD PMID:11040061 NCBI chr 5:24,319,589...24,351,684
Ensembl chr 5:24,319,589...24,351,604
JBrowse link
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 multiple interactions
affects abundance
EXP Dantrolene inhibits the reaction [KCNJ11 protein mutant form results in increased abundance of Calcium]; KCNJ11 protein affects the reaction [[Manganese co-treated with Dobutamine] results in increased abundance of Calcium]; W 7 inhibits the reaction [KCNJ11 protein mutant form results in increased abundance of Calcium]
KCNJ11 protein affects the abundance of Calcium
CTD PMID:17189350 NCBI chr 7:46,097,123...46,100,952
Ensembl chr 7:46,093,953...46,100,764
JBrowse link
G Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 multiple interactions
increases response to substance
ISO [KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium; Lithocholic Acid promotes the reaction [[KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium]
KCNMA1 mRNA alternative form results in increased susceptibility to Calcium
CTD PMID:22123969 PMID:28090300 NCBI chr14:23,292,288...24,005,110
Ensembl chr14:23,289,431...24,014,491
JBrowse link
G Kcnmb1 potassium large conductance calcium-activated channel, subfamily M, beta member 1 multiple interactions ISO [KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium; Lithocholic Acid promotes the reaction [[KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium] CTD PMID:22123969 NCBI chr11:33,962,955...33,973,641
Ensembl chr11:33,963,013...33,973,641
JBrowse link
G Kcnn2 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 increases activity
multiple interactions
ISO Calcium results in increased activity of KCNN2 protein
cyclohexyl-(2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl)amine promotes the reaction [Calcium results in increased activity of KCNN2 protein]
CTD PMID:17486140 NCBI chr18:45,268,750...45,685,887
Ensembl chr18:45,268,860...45,686,024
JBrowse link
G Kcnn3 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 multiple interactions
increases activity
ISO 6,7-dichloro-1H-indole-2,3-dione 3-oxime promotes the reaction [Calcium results in increased activity of KCNN3 protein]; cyclohexyl-(2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl)amine promotes the reaction [Calcium results in increased activity of KCNN3 protein] CTD PMID:17486140 NCBI chr 3:89,520,164...89,672,494
Ensembl chr 3:89,520,164...89,675,132
JBrowse link
G Kcnn4 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 affects abundance
multiple interactions
ISO KCNN4 protein affects the abundance of Calcium
KCNN4 protein affects the reaction [Calcium results in increased transport of Potassium]
CTD PMID:11826162 PMID:14985237 NCBI chr 7:24,369,826...24,385,212
Ensembl chr 7:24,370,263...24,386,690
JBrowse link
G Kdr kinase insert domain protein receptor multiple interactions ISO
EXP
[VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium; TRPC6 protein promotes the reaction [[VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium]
Calcium promotes the reaction [Corticosterone results in decreased expression of KDR protein]
CTD PMID:14551041 PMID:21647420 NCBI chr 5:75,932,827...75,979,072
Ensembl chr 5:75,932,827...75,978,458
JBrowse link
G Khsrp KH-type splicing regulatory protein multiple interactions ISO Calcium deficiency inhibits the reaction [KHSRP protein binds to PTH 3' UTR] CTD PMID:18583400 NCBI chr17:57,021,049...57,031,507
Ensembl chr17:57,021,051...57,031,522
JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor multiple interactions EXP 2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; [KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium; Flufenamic Acid inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin promotes the reaction [2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]] CTD PMID:18948403 NCBI chr 1:133,321,887...133,329,722
Ensembl chr 1:133,309,827...133,329,722
Ensembl chr 1:133,309,827...133,329,722
JBrowse link
G Kiss1r KISS1 receptor multiple interactions EXP 2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; [KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium; Flufenamic Acid inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin promotes the reaction [2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]] CTD PMID:18948403 NCBI chr10:79,916,952...79,924,088
Ensembl chr10:79,916,971...79,922,273
JBrowse link
G Kl klotho affects abundance
multiple interactions
EXP KL protein affects the abundance of Calcium
KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]]
CTD PMID:11796525 PMID:23747339 NCBI chr 5:150,952,607...150,993,817
Ensembl chr 5:150,952,607...150,993,817
JBrowse link
G Klk1 kallikrein 1 decreases activity ISO Calcium results in decreased activity of KLK1 protein CTD PMID:15558947 NCBI chr 7:44,225,360...44,229,622
Ensembl chr 7:44,225,360...44,229,618
JBrowse link
G Klk8 kallikrein related-peptidase 8 increases activity ISO Calcium results in increased activity of KLK8 protein CTD PMID:16800733 NCBI chr 7:43,797,532...43,803,826
Ensembl chr 7:43,797,577...43,803,826
JBrowse link
G Kng2 kininogen 2 affects abundance
increases abundance
multiple interactions
ISO
EXP
KNG1 protein affects the abundance of Calcium
KNG1 protein modified form results in increased abundance of Calcium
[KNG1 protein alternative form co-treated with Calcium] results in increased secretion of CALCA protein; Calcium affects the reaction [KNG1 protein results in increased secretion of Excitatory Amino Acid Agents]
B 4162 inhibits the reaction [pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]]; BDKRB2 protein affects the reaction [pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]]; CALR protein promotes the reaction [KNG1 protein modified form results in increased abundance of Calcium]; KNG1 protein affects the transport of and affects the localization of Calcium; pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]
BDKRB2 protein affects the reaction [KNG1 protein affects the abundance of Calcium]
KNG1 protein results in increased abundance of Calcium
CTD PMID:7961812 PMID:8592139 PMID:10535458 PMID:12582005 PMID:16473424 More... NCBI chr16:22,985,852...23,029,101
Ensembl chr16:22,985,854...23,029,482
JBrowse link
G Krt1 keratin 1 multiple interactions
increases expression
EXP
ISO
12-Hydroxy-5,8,10,14-eicosatetraenoic Acid inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; 15-hydroxy-5,8,11,13-eicosatetraenoic acid inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; 8-hydroxyeicosatetraenoic acid promotes the reaction [Calcium results in increased expression of KRT1 mRNA]; Masoprocol inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; morin inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; Quercetin inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of KRT1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of KRT1 protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; SB 203580 inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; SB 203580 inhibits the reaction [Calcium results in increased expression of KRT1 protein]; WNT5A protein promotes the reaction [Calcium results in increased expression of KRT1 mRNA]; WNT5A protein promotes the reaction [Calcium results in increased expression of KRT1 protein]
Calcium results in increased expression of KRT1 mRNA; Calcium results in increased expression of KRT1 protein
CTD PMID:12069687 PMID:21524694 PMID:24658506 NCBI chr15:101,845,426...101,850,786
Ensembl chr15:101,845,426...101,850,794
JBrowse link
G Lep leptin affects abundance
multiple interactions
affects secretion
increases transport
affects expression
decreases abundance
EXP
ISO
LEP protein affects the abundance of Calcium
Calcium deficiency inhibits the reaction [[Glucose co-treated with INS1 protein] results in increased secretion of LEP protein]
Calcium deficiency affects the secretion of LEP protein
LEP protein results in increased transport of Calcium
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [LEP protein results in increased transport of Calcium]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [LEP protein results in increased transport of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [LEP protein results in increased transport of Calcium]; acetovanillone inhibits the reaction [LEP protein affects the abundance of Calcium]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [LEP protein results in increased transport of Calcium]; BQ 788 inhibits the reaction [LEP protein affects the abundance of Calcium]; Calcium promotes the reaction [LEP protein results in increased transport of Calcium]; cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [LEP protein affects the abundance of Calcium]; edelfosine inhibits the reaction [LEP protein results in increased transport of Calcium]; Flufenamic Acid inhibits the reaction [LEP protein results in increased transport of Calcium]; JAK2 protein promotes the reaction [LEP protein results in increased transport of Calcium]; Lanthanum promotes the reaction [LEP protein results in increased transport of Calcium]; LEP protein promotes the reaction [TRPC1 protein results in increased transport of Calcium]; LEP protein promotes the reaction [TRPC4 protein results in increased transport of Calcium]; LEP protein promotes the reaction [TRPC5 protein results in increased transport of Calcium]; Wortmannin inhibits the reaction [LEP protein results in increased transport of Calcium]
Calcium affects the expression of LEP mRNA
LEP protein results in decreased abundance of Calcium
CTD PMID:10780946 PMID:14657008 PMID:15913539 PMID:16380530 PMID:20107083 NCBI chr 6:29,060,221...29,073,876
Ensembl chr 6:29,060,220...29,073,877
JBrowse link
G Lepr leptin receptor affects expression ISO Calcium affects the expression of LEPR mRNA CTD PMID:15913539 NCBI chr 4:101,717,137...101,815,352
Ensembl chr 4:101,717,404...101,815,352
JBrowse link
G Lif leukemia inhibitory factor increases abundance ISO LIF protein results in increased abundance of Calcium CTD PMID:11073891 NCBI chr11:4,257,568...4,272,514
Ensembl chr11:4,257,557...4,272,514
JBrowse link
G Lor loricrin increases expression
multiple interactions
ISO Calcium results in increased expression of LORICRIN mRNA; Calcium results in increased expression of LORICRIN protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of LORICRIN mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of LORICRIN protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; SB 203580 inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; SB 203580 inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; WNT5A protein promotes the reaction [Calcium results in increased expression of LORICRIN mRNA]; WNT5A protein promotes the reaction [Calcium results in increased expression of LORICRIN protein]
CTD PMID:21524694 PMID:24658506 NCBI chr 3:92,080,271...92,083,142
Ensembl chr 3:92,080,271...92,083,142
JBrowse link
G Lypla1 lysophospholipase 1 multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of LYPLA1 mRNA CTD PMID:15913539 NCBI chr 1:4,807,823...4,846,735
Ensembl chr 1:4,807,788...4,848,410
JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 multiple interactions ISO [Sumatriptan results in increased abundance of Calcium] inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA]; Calcium inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA] CTD PMID:12574409 NCBI chr 9:64,185,769...64,253,605
Ensembl chr 9:64,185,770...64,253,631
JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 affects expression ISO Calcium affects the expression of MAP2K2 mRNA CTD PMID:15913539 NCBI chr10:81,105,913...81,124,697
Ensembl chr10:81,105,915...81,133,975
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 increases phosphorylation
multiple interactions
ISO
EXP
Calcium results in increased phosphorylation of MAPK1 protein
Calcium promotes the reaction [Diclofenac results in increased phosphorylation of MAPK1 protein]
Calcium affects the reaction [Ptychodiscus brevis T2 toxin affects the phosphorylation of MAPK1 protein]; Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK1 protein]
Calcium deficiency inhibits the reaction [Carbachol results in increased phosphorylation of and results in increased activity of MAPK1 protein]
CTD PMID:10660688 PMID:15086530 PMID:16877402 PMID:17537980 PMID:18758753 More... NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 affects expression ISO Calcium affects the expression of MAPK14 mRNA CTD PMID:15913539 NCBI chr17:28,691,342...28,748,405
Ensembl chr17:28,691,329...28,748,406
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 increases phosphorylation
multiple interactions
ISO
EXP
Calcium results in increased phosphorylation of MAPK3 protein
Calcium promotes the reaction [Diclofenac results in increased phosphorylation of MAPK3 protein]
Calcium deficiency inhibits the reaction [Carbachol results in increased phosphorylation of and results in increased activity of MAPK3 protein]
Calcium affects the reaction [Ptychodiscus brevis T2 toxin affects the phosphorylation of MAPK3 protein]; Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]; Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK3 protein]
CTD PMID:10660688 PMID:15086530 PMID:16877402 PMID:17537980 PMID:18758753 More... NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mapk4 mitogen-activated protein kinase 4 affects expression ISO Calcium affects the expression of MAPK4 mRNA CTD PMID:15913539 NCBI chr18:73,928,486...74,065,434
Ensembl chr18:73,928,486...74,065,359
JBrowse link
G Marco macrophage receptor with collagenous structure multiple interactions ISO Calcium promotes the reaction [titanium dioxide binds to MARCO protein] CTD PMID:18836211 NCBI chr 1:120,474,538...120,505,024
Ensembl chr 1:120,474,538...120,505,024
JBrowse link
G Mcoln1 mucolipin 1 multiple interactions ISO [NAADP results in increased activity of MCOLN1 protein] which affects the localization of Calcium CTD PMID:21613607 NCBI chr 8:3,500,519...3,515,232
Ensembl chr 8:3,500,457...3,515,232
JBrowse link
G Mcu mitochondrial calcium uniporter affects localization EXP MCU protein affects the localization of Calcium CTD PMID:22829870 NCBI chr10:59,446,984...59,617,409
Ensembl chr10:59,446,984...59,616,692
JBrowse link
G Mgp matrix Gla protein multiple interactions
affects expression
affects binding
ISO [Calcium binds to MGP protein] which binds to and results in decreased activity of BMP4 protein; [Edetic Acid inhibits the reaction [Calcium binds to MGP protein]] inhibits the reaction [MGP protein binds to BMP4 protein]; Edetic Acid inhibits the reaction [Calcium binds to MGP protein]
Calcium affects the expression of MGP mRNA
CTD PMID:15913539 PMID:18369157 NCBI chr 6:136,872,435...136,875,823
Ensembl chr 6:136,872,435...136,875,823
JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) affects expression ISO Calcium affects the expression of MMP1 mRNA; Calcium affects the expression of MMP1 protein CTD PMID:17508023 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of MTOR protein] CTD PMID:12935885 NCBI chr 4:148,448,582...148,557,685
Ensembl chr 4:148,448,611...148,557,683
JBrowse link
G Mybpc3 myosin binding protein C, cardiac multiple interactions
increases response to substance
EXP epigallocatechin gallate inhibits the reaction [MYBPC3 gene mutant form results in increased susceptibility to Calcium] CTD PMID:27994558 NCBI chr 2:91,118,114...91,136,516
Ensembl chr 2:91,118,144...91,136,516
JBrowse link
G Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta increases transport ISO MYH7 gene mutant form results in increased transport of Calcium CTD PMID:29741611 NCBI chr14:54,970,684...54,994,626
Ensembl chr14:54,970,684...54,994,626
JBrowse link
G Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow multiple interactions ISO Calcium affects the reaction [MYL2 gene SNP affects the abundance of Lead] CTD PMID:28212632 NCBI chr 5:122,092,724...122,113,473
Ensembl chr 5:122,100,951...122,113,472
JBrowse link
G Myl3 myosin, light polypeptide 3 affects expression ISO Calcium affects the expression of MYL3 mRNA CTD PMID:15913539 NCBI chr 9:110,763,678...110,769,802
Ensembl chr 9:110,741,861...110,769,798
JBrowse link
G Myl9 myosin, light polypeptide 9, regulatory multiple interactions
affects phosphorylation
decreases phosphorylation
ISO [[Calcium results in increased activity of MYLK protein] which results in increased phosphorylation of MYL9 protein] which results in decreased secretion of REN protein; [CACNA1D protein results in increased uptake of Calcium] which results in increased phosphorylation of MYL9 protein; [Escin affects the susceptibility to Calcium] which results in increased phosphorylation of MYL9 protein; Glycodeoxycholic Acid inhibits the reaction [[Escin affects the susceptibility to Calcium] which results in increased phosphorylation of MYL9 protein]; Y 27632 inhibits the reaction [[Escin affects the susceptibility to Calcium] which results in increased phosphorylation of MYL9 protein]
Calcium affects the phosphorylation of MYL9 protein
Calcium deficiency results in decreased phosphorylation of MYL9 protein
CTD PMID:7503253 PMID:9618396 PMID:17272349 PMID:29660437 NCBI chr 2:156,775,408...156,781,657
Ensembl chr 2:156,775,420...156,781,658
JBrowse link
G Mylk myosin, light polypeptide kinase increases activity
multiple interactions
ISO Calcium deficiency results in increased activity of MYLK protein; Calcium results in increased activity of MYLK protein
[[Calcium results in increased activity of MYLK protein] which results in increased phosphorylation of MYL9 protein] which results in decreased secretion of REN protein
ML 7 inhibits the reaction [Calcium deficiency results in increased activity of MYLK protein]
CTD PMID:9618396 PMID:10640419 PMID:11054866 NCBI chr16:34,745,199...35,002,436
Ensembl chr16:34,745,210...35,002,420
JBrowse link
G Myo1b myosin IB increases activity ISO Calcium deficiency results in increased activity of MYO1B protein CTD PMID:10419463 NCBI chr 1:51,749,758...51,916,063
Ensembl chr 1:51,749,765...51,916,071
JBrowse link
G Myo5a myosin VA affects activity EXP Calcium affects the activity of MYO5A protein CTD PMID:10660602 NCBI chr 9:75,069,799...75,223,688
Ensembl chr 9:75,071,015...75,223,688
JBrowse link
G Naip2 NLR family, apoptosis inhibitory protein 2 decreases response to substance EXP NAIP protein results in decreased susceptibility to Calcium CTD PMID:12445469 NCBI chr13:100,144,063...100,202,122
Ensembl chr13:100,144,063...100,202,092
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 affects abundance EXP NCF1 protein affects the abundance of Calcium CTD PMID:16280459 NCBI chr 5:134,220,053...134,229,628
Ensembl chr 5:134,220,053...134,229,625
JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of NDUFS1 mRNA CTD PMID:15913539 NCBI chr 1:63,143,592...63,176,822
Ensembl chr 1:63,143,596...63,176,833
JBrowse link
G Nedd4 neural precursor cell expressed, developmentally down-regulated 4 affects expression ISO Calcium affects the expression of NEDD4 mRNA CTD PMID:15913539 NCBI chr 9:72,662,331...72,749,851
Ensembl chr 9:72,662,346...72,749,852
JBrowse link
G Nedd4l neural precursor cell expressed, developmentally down-regulated gene 4-like multiple interactions EXP [NEDD4L gene mutant form results in increased susceptibility to Sodium, Dietary] which results in increased abundance of Calcium; Thiazides inhibits the reaction [[NEDD4L gene mutant form results in increased susceptibility to Sodium, Dietary] which results in increased abundance of Calcium] CTD PMID:23348737 NCBI chr18:64,884,480...65,217,826
Ensembl chr18:64,887,705...65,217,828
JBrowse link
G Nefl neurofilament, light polypeptide multiple interactions ISO Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of NEFL protein]; calpeptin inhibits the reaction [Calcium results in increased degradation of NEFL protein]; Indomethacin inhibits the reaction [Calcium results in increased degradation of NEFL protein] CTD PMID:11071371 PMID:21879721 NCBI chr14:68,083,863...68,089,095
Ensembl chr14:68,083,863...68,089,095
JBrowse link
G Nefm neurofilament, medium polypeptide multiple interactions ISO Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of NEFM protein] CTD PMID:21879721 NCBI chr14:68,119,545...68,125,004
Ensembl chr14:68,082,590...68,124,846
JBrowse link
G Nek9 NIMA (never in mitosis gene a)-related expressed kinase 9 affects expression ISO Calcium affects the expression of NEK9 mRNA CTD PMID:15913539 NCBI chr12:85,299,514...85,339,362
Ensembl chr12:85,299,514...85,339,362
JBrowse link
G Nf1 neurofibromin 1 decreases transport EXP NF1 protein results in decreased transport of Calcium CTD PMID:21949590 NCBI chr11:79,339,590...79,581,609
Ensembl chr11:79,339,693...79,581,612
JBrowse link
G Nfatc2 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 multiple interactions EXP 4-methyl-4'-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)-1,2,3-thiadiazole-5-carboxanilide inhibits the reaction [[Muscarine co-treated with Calcium] affects the localization of NFATC2 protein]; 4-methyl-4'-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)-1,2,3-thiadiazole-5-carboxanilide inhibits the reaction [[Thapsigargin co-treated with Calcium] affects the localization of NFATC2 protein]; [Muscarine co-treated with Calcium] affects the localization of NFATC2 protein; [Thapsigargin co-treated with Calcium] affects the localization of NFATC2 protein CTD PMID:24990931 NCBI chr 2:168,476,410...168,601,657
Ensembl chr 2:168,476,410...168,601,657
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 increases abundance EXP NFE2L2 gene mutant form results in increased abundance of Calcium CTD PMID:29618784 NCBI chr 2:75,675,513...75,704,663
Ensembl chr 2:75,675,513...75,704,641
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha affects expression
multiple interactions
ISO Calcium affects the expression of NFKBIA mRNA
Calcium affects the reaction [Morphine inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]
CTD PMID:15913539 PMID:24068670 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647
JBrowse link
G Ngb neuroglobin affects transport ISO NGB protein affects the transport of Calcium CTD PMID:19154338 NCBI chr12:87,097,531...87,102,539
Ensembl chr12:87,097,531...87,102,539
JBrowse link
G Ngf nerve growth factor multiple interactions
increases uptake
ISO [NGF protein co-treated with 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester] results in increased uptake of Calcium; [NGF protein co-treated with Adenosine Triphosphate] results in increased uptake of Calcium; cadmium acetate inhibits the reaction [NGF protein results in increased uptake of Calcium]; Cadmium inhibits the reaction [NGF protein results in increased uptake of Calcium]; calmidazolium inhibits the reaction [NGF protein results in increased uptake of Calcium]; Fluphenazine inhibits the reaction [NGF protein results in increased uptake of Calcium]; Nifedipine inhibits the reaction [NGF protein results in increased uptake of Calcium]; Okadaic Acid promotes the reaction [NGF protein results in increased uptake of Calcium]; Staurosporine inhibits the reaction [NGF protein results in increased uptake of Calcium] CTD PMID:1374475 NCBI chr 3:102,469,919...102,521,013
Ensembl chr 3:102,469,919...102,521,013
JBrowse link
G Noa1 nitric oxide associated 1 multiple interactions ISO [Tamoxifen results in increased abundance of Calcium] which results in increased activity of NOA1 protein CTD PMID:17283165 NCBI chr 5:77,294,169...77,310,413
Ensembl chr 5:77,294,182...77,310,084
JBrowse link
G Nos1 nitric oxide synthase 1, neuronal multiple interactions ISO [Calcium binds to CALM1 protein] promotes the reaction [NOS1 protein results in increased chemical synthesis of Nitric Oxide]; [Calcium binds to CALM1 protein] which binds to and affects the folding of and results in increased activity of NOS1 protein CTD PMID:17098364 NCBI chr 5:117,866,839...117,958,840
Ensembl chr 5:117,781,032...117,958,840
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell affects response to substance
increases activity
multiple interactions
EXP
ISO
NOS3 protein affects the susceptibility to Calcium
Calcium results in increased activity of NOS3 protein
Calcium affects the reaction [Polycyclic Aromatic Hydrocarbons results in increased expression of and results in increased activity of NOS3 protein]; Calcium deficiency inhibits the reaction [Digitoxin results in increased activity of NOS3 protein]; Calcium deficiency inhibits the reaction [ginsenoside Re results in increased phosphorylation of NOS3 protein]
CTD PMID:15183461 PMID:17403420 PMID:17490654 PMID:19380615 PMID:19446813 More... NCBI chr 5:24,364,816...24,384,474
Ensembl chr 5:24,364,810...24,384,474
JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions EXP 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid inhibits the reaction [NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]]; NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]] CTD PMID:24912985 NCBI chr  X:134,086,421...134,137,711
Ensembl chr  X:134,086,421...134,221,956
JBrowse link
G Nppc natriuretic peptide type C increases uptake
multiple interactions
ISO NPPC protein results in increased uptake of Calcium
Ammonia inhibits the reaction [NPPC protein results in increased uptake of Calcium]; Nimodipine inhibits the reaction [NPPC protein results in increased uptake of Calcium]
CTD PMID:18222015 NCBI chr 1:86,666,293...86,670,573
Ensembl chr 1:86,666,291...86,670,571
JBrowse link
G Npr1 natriuretic peptide receptor 1 affects expression ISO Calcium affects the expression of NPR1 mRNA CTD PMID:15913539 NCBI chr 3:90,450,591...90,465,928
Ensembl chr 3:90,450,591...90,465,866
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 affects expression ISO Calcium affects the expression of NR0B2 mRNA CTD PMID:15913539 NCBI chr 4:133,553,376...133,556,686
Ensembl chr 4:133,553,376...133,556,536
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 affects expression ISO Calcium affects the expression of NR1D2 mRNA CTD PMID:15913539 NCBI chr14:18,204,056...18,239,106
Ensembl chr14:18,204,054...18,239,127
JBrowse link
G Nrxn1 neurexin I multiple interactions EXP Calcium affects the reaction [alpha-latrotoxin binds to NRXN1 protein]; Calcium affects the reaction [black widow spider venom binds to NRXN1 protein] CTD PMID:9430716 NCBI chr17:90,033,644...91,093,159
Ensembl chr17:90,033,631...91,093,071
JBrowse link
G Nucb2 nucleobindin 2 multiple interactions ISO KT 5720 inhibits the reaction [NUCB2 protein results in increased import of Calcium] CTD PMID:17627999 NCBI chr 7:116,504,352...116,540,588
Ensembl chr 7:116,504,369...116,540,584
JBrowse link
G Ocln occludin multiple interactions ISO Calcium deficiency inhibits the reaction [TJP1 protein binds to OCLN protein] CTD PMID:11054866 NCBI chr13:100,496,504...100,552,718
Ensembl chr13:100,496,507...100,552,718
JBrowse link
G Olfr412 olfactory receptor 412 multiple interactions ISO [bourgeonal binds to and results in increased activity of OR1D2 protein] which results in increased abundance of Calcium CTD PMID:21454470 NCBI chr11:74,364,671...74,365,609
Ensembl chr11:74,362,069...74,366,218
JBrowse link
G Olfr73 olfactory receptor 73 multiple interactions EXP [ethyl vanillin binds to and results in increased activity of OLFR73 protein] which results in increased transport of Calcium; [Eugenol binds to and results in increased activity of OLFR73 protein] which results in increased transport of Calcium; [Eugenol binds to OLFR73 protein] which results in increased transport of Calcium; [isomethyleugenol binds to and results in decreased activity of OLFR73 protein] which results in decreased transport of Calcium; isomethyleugenol inhibits the reaction [[Eugenol binds to OLFR73 protein] which results in increased transport of Calcium] CTD PMID:14685265 PMID:15716417 NCBI chr 2:88,034,196...88,035,137
Ensembl chr 2:88,032,288...88,037,699
JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions EXP [Tetradecanoylphorbol Acetate co-treated with Calcium] inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]] CTD PMID:18652891 NCBI chr10:6,758,593...7,038,209
Ensembl chr10:6,758,506...7,038,198
JBrowse link
G Orai1 ORAI calcium release-activated calcium modulator 1 multiple interactions
increases uptake
ISO
EXP
[Calcium affects the activity of and affects the localization of STIM1 protein] which affects the activity of ORAI1 protein
ORAI1 protein results in increased uptake of Calcium
CTD PMID:23212906 PMID:24990931 NCBI chr 5:123,015,074...123,030,452
Ensembl chr 5:123,015,074...123,030,456
JBrowse link
G Oxt oxytocin multiple interactions ISO OXT protein promotes the reaction [TRPC3 protein results in increased transport of Calcium]
[Thapsigargin results in increased transport of Calcium] which results in increased secretion of OXT protein
CTD PMID:12700192 PMID:22028774 NCBI chr 2:130,574,519...130,577,054
Ensembl chr 2:130,576,173...130,577,054
JBrowse link
G P2rx3 purinergic receptor P2X, ligand-gated ion channel, 3 multiple interactions ISO [alpha,beta-methyleneadenosine 5'-triphosphate binds to and results in increased activity of P2RX3 protein] which results in increased abundance of Calcium; Trichloroethylene inhibits the reaction [[alpha,beta-methyleneadenosine 5'-triphosphate binds to and results in increased activity of P2RX3 protein] which results in increased abundance of Calcium] CTD PMID:12694404 NCBI chr 2:84,996,549...85,037,108
Ensembl chr 2:84,998,583...85,037,462
JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 multiple interactions ISO [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium; KN 62 inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium]; protoberberine analog inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium] CTD PMID:21320518 NCBI chr 5:122,643,927...122,692,336
Ensembl chr 5:122,643,911...122,691,432
JBrowse link
G P2ry1 purinergic receptor P2Y, G-protein coupled 1 multiple interactions ISO [Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein] which results in increased abundance of Calcium; Calcium affects the reaction [P2RY1 protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; Trichloroethylene inhibits the reaction [[Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein] which results in increased abundance of Calcium]
[N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate binds to and results in decreased activity of P2RY1 protein] inhibits the reaction [Adenosine Triphosphate results in increased uptake of Calcium]
CTD PMID:12694404 PMID:16236484 PMID:16973929 NCBI chr 3:61,002,785...61,008,982
Ensembl chr 3:61,002,795...61,008,982
JBrowse link
G P2ry2 purinergic receptor P2Y, G-protein coupled 2 multiple interactions
affects response to substance
ISO
EXP
[Adenosine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Calcium
P2RY2 protein affects the susceptibility to Calcium
[Adenosine Triphosphate results in increased activity of P2RY2 protein] which results in increased uptake of Calcium; Go 6976 promotes the reaction [P2RY2 protein results in increased uptake of Calcium]; Tetradecanoylphorbol Acetate inhibits the reaction [P2RY2 protein results in increased uptake of Calcium]
CTD PMID:11527950 PMID:17003265 PMID:18343036 NCBI chr 7:100,996,568...101,012,053
Ensembl chr 7:100,996,568...101,012,866
JBrowse link
G P2ry4 pyrimidinergic receptor P2Y, G-protein coupled, 4 multiple interactions ISO [Adenosine Triphosphate binds to and results in increased activity of P2RY4 protein] which results in increased abundance of Calcium; Trichloroethylene inhibits the reaction [[Adenosine Triphosphate binds to and results in increased activity of P2RY4 protein] which results in increased abundance of Calcium] CTD PMID:12694404 NCBI chr  X:100,588,358...100,594,927
Ensembl chr  X:100,590,154...100,594,869
JBrowse link
G P4hb prolyl 4-hydroxylase, beta polypeptide multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of P4HB mRNA CTD PMID:15913539 NCBI chr11:120,560,298...120,573,253
Ensembl chr11:120,560,298...120,573,253
JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 increases abundance
multiple interactions
ISO
EXP
PAFAH1B1 protein results in increased abundance of Calcium
Calcium promotes the reaction [PAFAH1B1 protein binds to IQGAP1 protein binds to CDC42 protein]
PKD1 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium]; PKD2 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium]
CTD PMID:15001556 PMID:16369480 NCBI chr11:74,673,949...74,724,384
Ensembl chr11:74,673,949...74,724,670
JBrowse link
G Parg poly (ADP-ribose) glycohydrolase multiple interactions EXP PARG protein promotes the reaction [Hydrogen Peroxide results in increased uptake of Calcium] CTD PMID:20878536 NCBI chr14:32,201,930...32,298,714
Ensembl chr14:32,201,949...32,297,550
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions EXP PARP1 protein promotes the reaction [Hydrogen Peroxide results in increased uptake of Calcium] CTD PMID:20878536 NCBI chr 1:180,568,891...180,600,999
Ensembl chr 1:180,568,924...180,601,254
JBrowse link
G Pask PAS domain containing serine/threonine kinase multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of PASK mRNA CTD PMID:15913539 NCBI chr 1:93,309,437...93,343,522
Ensembl chr 1:93,308,770...93,343,482
JBrowse link
G Pax6 paired box 6 affects expression ISO Calcium affects the expression of PAX6 mRNA CTD PMID:15913539 NCBI chr 2:105,668,896...105,698,410
Ensembl chr 2:105,668,900...105,697,364
JBrowse link
G Pax8 paired box 8 affects expression ISO Calcium affects the expression of PAX8 mRNA CTD PMID:15913539 NCBI chr 2:24,420,551...24,475,599
Ensembl chr 2:24,420,560...24,475,599
JBrowse link
G Pcdh19 protocadherin 19 affects binding ISO Calcium binds to PCDH19 protein CTD PMID:18469813 NCBI chr  X:133,582,860...133,689,044
Ensembl chr  X:133,582,860...133,688,987
JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide increases import ISO PDGFB protein results in increased import of Calcium CTD PMID:19576918 NCBI chr15:79,995,865...80,024,614
Ensembl chr15:79,995,874...80,014,977
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase, isoenzyme 1 multiple interactions
affects abundance
ISO
EXP
PDK1 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]
PDK1 protein affects the abundance of Calcium
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester affects the reaction [PDK1 protein affects the abundance of Calcium]; [PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium; Adenosine Triphosphate promotes the reaction [PDK1 protein affects the abundance of Calcium]; PDK1 protein affects the reaction [Thapsigargin affects the abundance of Calcium]; tubacin affects the reaction [[PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium]; tubacin affects the reaction [PDK1 protein affects the abundance of Calcium]; tubacin inhibits the reaction [PDK1 protein affects the reaction [Thapsigargin affects the abundance of Calcium]]
CTD PMID:28634229 PMID:28887310 NCBI chr 2:71,873,215...71,903,858
Ensembl chr 2:71,873,224...71,903,858
JBrowse link
G Pdzd3 PDZ domain containing 3 multiple interactions EXP [[USP2 gene mutant form results in increased expression of PDZD3 protein] which results in increased activity of TRPV6 protein] which results in increased uptake of Calcium CTD PMID:26756164 NCBI chr 9:44,247,312...44,251,464
Ensembl chr 9:44,247,307...44,251,471
JBrowse link
G Pgp phosphoglycolate phosphatase decreases activity EXP Calcium results in decreased activity of PGP protein CTD PMID:24338473 NCBI chr17:24,470,426...24,473,110
Ensembl chr17:24,470,392...24,473,110
JBrowse link
G Pick1 protein interacting with C kinase 1 multiple interactions ISO Calcium affects the reaction [PICK1 protein binds to AGO2 protein]; Calcium deficiency inhibits the reaction [Excitatory Amino Acid Agonists inhibits the reaction [PICK1 protein binds to AGO2 protein]]; Calcium promotes the reaction [PICK1 protein binds to GRIA2 protein] CTD PMID:28404816 NCBI chr15:79,229,140...79,249,466
Ensembl chr15:79,229,173...79,249,484
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta affects transport ISO PIK3CB protein affects the transport of Calcium CTD PMID:11597992 NCBI chr 9:99,038,402...99,140,235
Ensembl chr 9:99,036,654...99,140,621
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta affects transport EXP PIK3CD protein affects the transport of Calcium CTD PMID:16179367 NCBI chr 4:149,649,168...149,702,566
Ensembl chr 4:149,649,168...149,702,571
JBrowse link
G Pip5k1b phosphatidylinositol-4-phosphate 5-kinase, type 1 beta affects expression ISO Calcium affects the expression of PIP5K1B mRNA CTD PMID:15913539 NCBI chr19:24,294,794...24,555,872
Ensembl chr19:24,294,794...24,555,872
JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting multiple interactions ISO
EXP
PKD1 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium]
PKD1 protein affects the reaction [Caffeine affects the abundance of Calcium]; PKD1 protein affects the reaction [Thapsigargin affects the abundance of Calcium]
CTD PMID:15001556 PMID:18679710 NCBI chr17:24,548,689...24,596,514
Ensembl chr17:24,549,834...24,596,508
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel increases transport
multiple interactions
ISO
EXP
PKD2 protein results in increased transport of Calcium
PKD2 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium]
IFT88 protein affects the reaction [PKD2 protein results in increased uptake of Calcium]
CTD PMID:15001556 PMID:15100357 PMID:16396941 NCBI chr 5:104,453,982...104,505,819
Ensembl chr 5:104,459,450...104,505,819
JBrowse link
G Pklr pyruvate kinase liver and red blood cell multiple interactions ISO Calcium inhibits the reaction [Phenylephrine results in decreased activity of PKLR protein] CTD PMID:747652 NCBI chr 3:89,136,122...89,146,815
Ensembl chr 3:89,136,142...89,146,784
JBrowse link
G Pla2g1b phospholipase A2, group IB, pancreas multiple interactions
increases abundance
ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[PLA2G1B protein results in increased abundance of Calcium] which results in increased expression of CXCL8 protein]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [PLA2G1B protein results in increased abundance of Calcium]; [PLA2G1B protein results in increased abundance of Calcium] which results in increased expression of CXCL8 protein CTD PMID:15528384 NCBI chr 5:115,466,142...115,474,722
Ensembl chr 5:115,466,262...115,474,722
JBrowse link
G Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid) increases uptake
multiple interactions
ISO PLA2G2A protein results in increased uptake of Calcium
BQ 788 inhibits the reaction [EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium]]; EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium]
CTD PMID:15695168 NCBI chr 4:138,831,857...138,835,189
Ensembl chr 4:138,831,857...138,835,186
JBrowse link
G Pla2g6 phospholipase A2, group VI increases activity
multiple interactions
ISO Calcium deficiency results in increased activity of PLA2G6 protein
6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2H-pyran-2-one inhibits the reaction [[Lipopolysaccharides results in increased expression of and results in increased activity of PLA2G6 protein] which results in increased susceptibility to Calcium]; [Lipopolysaccharides results in increased expression of and results in increased activity of PLA2G6 protein] which results in increased susceptibility to Calcium
CTD PMID:17885217 PMID:21178110 NCBI chr15:79,286,228...79,328,385
Ensembl chr15:79,286,228...79,328,390
JBrowse link
G Plcg2 phospholipase C, gamma 2 multiple interactions ISO Calcium promotes the reaction [PLCG2 protein mutant form results in increased chemical synthesis of Inositol Phosphates]; Calcium promotes the reaction [PLCG2 protein results in increased chemical synthesis of Inositol Phosphates] CTD PMID:27542411 NCBI chr 8:117,498,275...117,635,142
Ensembl chr 8:117,498,291...117,635,142
JBrowse link
G Pnoc prepronociceptin decreases abundance ISO PNOC protein results in decreased abundance of Calcium CTD PMID:21039959 NCBI chr14:65,400,673...65,425,564
Ensembl chr14:65,400,673...65,425,472
JBrowse link
G Pon1 paraoxonase 1 increases activity
multiple interactions
ISO Calcium results in increased activity of PON1 protein
[Calcium results in increased activity of PON1 protein] which affects the susceptibility to O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate; [Calcium results in increased activity of PON1 protein] which affects the susceptibility to oxamyl; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Aldicarb; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to methylparaoxon; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Paraoxon
[Calcium co-treated with 1,2-dioleoyl-sn-glycero-3-phosphoglycerol] results in increased stability of PON1 protein; [Calcium co-treated with Oleic Acid] results in increased stability of PON1 protein; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Aldicarb; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to methylparaoxon; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to oxamyl; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Paraoxon; Calcium promotes the reaction [Oleic Acid inhibits the reaction [4-hydroxymercuribenzoate results in decreased activity of PON1 protein]]
CTD PMID:12871208 PMID:27132127 NCBI chr 6:5,168,090...5,193,987
Ensembl chr 6:5,168,090...5,193,946
JBrowse link
G Pon2 paraoxonase 2 affects abundance
multiple interactions
ISO PON2 gene polymorphism affects the abundance of Calcium
Calcium inhibits the reaction [lead acetate results in decreased activity of PON2 protein]
CTD PMID:16141008 PMID:22271317 NCBI chr 6:5,264,620...5,298,345
Ensembl chr 6:5,264,147...5,298,455
JBrowse link
G Pou6f1 POU domain, class 6, transcription factor 1 affects expression ISO Calcium affects the expression of POU6F1 mRNA CTD PMID:15913539 NCBI chr15:100,575,318...100,600,061
Ensembl chr15:100,575,318...100,599,984
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP [GW 7647 binds to and results in increased activity of PPARA protein] affects the reaction [Glucose affects the abundance of Calcium]; [Oleylethanolamide binds to and results in increased activity of PPARA protein] affects the reaction [Glucose affects the abundance of Calcium]; [pirinixic acid binds to and results in increased activity of PPARA protein] affects the reaction [Glucose affects the abundance of Calcium] CTD PMID:19017711 NCBI chr15:85,734,910...85,806,851
Ensembl chr15:85,734,983...85,802,819
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha affects expression ISO Calcium affects the expression of PPP1CA mRNA CTD PMID:15913539 NCBI chr19:4,192,174...4,195,419
Ensembl chr19:4,192,065...4,195,420
JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta affects expression ISO Calcium affects the expression of PPP1CB mRNA CTD PMID:15913539 NCBI chr 5:32,458,848...32,493,713
Ensembl chr 5:32,458,843...32,517,433
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A multiple interactions ISO [Egtazic Acid co-treated with Calcium deficiency] results in increased expression of PPP1R15A mRNA CTD PMID:9878749 NCBI chr 7:45,522,917...45,526,268
Ensembl chr 7:45,522,916...45,526,268
JBrowse link
G Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform affects abundance
affects transport
EXP PPP2CA protein affects the abundance of Calcium
PPP2CA protein affects the transport of Calcium
CTD PMID:15247211 NCBI chr11:52,098,824...52,122,749
Ensembl chr11:52,098,681...52,127,778
JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) multiple interactions
affects response to substance
EXP PPP3R1 gene mutant form inhibits the reaction [ATP2A2 protein affects the transport of Calcium]; PPP3R1 gene mutant form inhibits the reaction [SLC8A1 protein affects the transport of Calcium]
PPP3R1 gene mutant form affects the susceptibility to Calcium
CTD PMID:19700627 NCBI chr11:17,159,298...17,200,380
Ensembl chr11:17,159,263...17,200,375
JBrowse link
G Prdx6 peroxiredoxin 6 multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of PRDX6 mRNA CTD PMID:15913539 NCBI chr 1:161,240,112...161,251,210
Ensembl chr 1:161,240,112...161,251,219
JBrowse link
G Prkca protein kinase C, alpha multiple interactions
increases response to substance
ISO [Tretinoin co-treated with Calcium] results in increased activity of PRKCA protein
PRKCA protein results in increased susceptibility to Calcium
CTD PMID:12388232 PMID:16114872 NCBI chr11:107,933,387...108,343,888
Ensembl chr11:107,933,387...108,343,928
JBrowse link
G Prkcb protein kinase C, beta multiple interactions EXP Calcium inhibits the reaction [Chlordecone results in increased activity of PRKCB protein]; Calcium inhibits the reaction [Dicofol results in increased activity of PRKCB protein] CTD PMID:1724372 NCBI chr 7:122,289,104...122,634,402
Ensembl chr 7:122,288,751...122,634,402
JBrowse link
G Prkcd protein kinase C, delta affects expression ISO Calcium affects the expression of PRKCD mRNA CTD PMID:15913539 NCBI chr14:30,595,353...30,626,414
Ensembl chr14:30,595,354...30,626,210
JBrowse link
G Prkce protein kinase C, epsilon multiple interactions
increases phosphorylation
affects response to substance
EXP
ISO
PRKCE protein affects the reaction [Oxygen deficiency results in increased abundance of Calcium]
Calcium results in increased phosphorylation of PRKCE protein
chelerythrine inhibits the reaction [Calcium results in increased phosphorylation of PRKCE protein]; PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]]
PRKCE protein affects the susceptibility to Calcium
CTD PMID:15242976 PMID:16793902 PMID:17087917 PMID:21562303 NCBI chr17:86,167,785...86,657,919
Ensembl chr17:86,167,785...86,657,919
JBrowse link
G Prkcg protein kinase C, gamma multiple interactions EXP [Tetradecanoylphorbol Acetate co-treated with Calcium] inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]] CTD PMID:18652891 NCBI chr 7:3,303,532...3,331,099
Ensembl chr 7:3,289,179...3,331,099
JBrowse link
G Prkd1 protein kinase D1 multiple interactions ISO PRKD1 promotes the reaction [Capsaicin results in increased uptake of Calcium]
PRKD1 mutant form inhibits the reaction [Capsaicin results in increased uptake of Calcium]
CTD PMID:15471852 NCBI chr12:50,341,226...50,649,271
Ensembl chr12:50,341,231...50,649,098
JBrowse link
G Prkg1 protein kinase, cGMP-dependent, type I increases response to substance EXP PRKG1 protein results in increased susceptibility to Calcium CTD PMID:16533816 NCBI chr19:30,564,487...31,765,268
Ensembl chr19:30,564,489...31,765,033
JBrowse link
G Prl prolactin multiple interactions ISO Calcium inhibits the reaction [PRL protein binds to PRLR protein] CTD PMID:6197504 NCBI chr13:27,057,570...27,065,204
Ensembl chr13:27,057,570...27,065,205
JBrowse link
G Prlr prolactin receptor affects expression
multiple interactions
ISO Calcium affects the expression of PRLR mRNA
Calcium inhibits the reaction [PRL protein binds to PRLR protein]
CTD PMID:6197504 PMID:15913539 NCBI chr15:10,177,238...10,349,190
Ensembl chr15:10,177,238...10,349,180
JBrowse link
G Prok2 prokineticin 2 multiple interactions
increases abundance
EXP PROKR1 protein affects the reaction [PROK2 protein results in increased abundance of Calcium] CTD PMID:16793879 PMID:17107623 NCBI chr 6:99,711,299...99,726,392
Ensembl chr 6:99,711,299...99,726,392
JBrowse link
G Prokr1 prokineticin receptor 1 multiple interactions EXP PROKR1 protein affects the reaction [Capsaicin results in increased abundance of Calcium]; PROKR1 protein affects the reaction [PROK2 protein results in increased abundance of Calcium] CTD PMID:16793879 NCBI chr 6:87,578,586...87,590,762
Ensembl chr 6:87,578,591...87,590,743
JBrowse link
G Ptafr platelet-activating factor receptor multiple interactions ISO RGS4 protein inhibits the reaction [PTAFR protein affects the localization of and affects the abundance of Calcium] CTD PMID:11297424 NCBI chr 4:132,564,067...132,582,683
Ensembl chr 4:132,564,067...132,582,683
JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 multiple interactions ISO PTGDR2 protein affects the abundance of and affects the localization of Calcium CTD PMID:16256979 NCBI chr19:10,924,519...10,942,511
Ensembl chr19:10,937,160...10,942,511
JBrowse link
G Ptger1 prostaglandin E receptor 1 (subtype EP1) multiple interactions
increases abundance
EXP 17-phenyltrinorprostaglandin E2 inhibits the reaction [PTGER1 protein results in increased abundance of Calcium] CTD PMID:11809688 NCBI chr 8:83,666,644...83,672,756
Ensembl chr 8:83,666,678...83,672,753
JBrowse link
G Ptger3 prostaglandin E receptor 3 (subtype EP3) multiple interactions ISO PTGER3 protein affects the reaction [Dinoprostone results in decreased transport of Calcium]; PTGER3 protein affects the reaction [ONO AE 248 results in decreased transport of Calcium] CTD PMID:12535167 NCBI chr 3:157,566,821...157,644,758
Ensembl chr 3:157,566,892...157,645,888
JBrowse link
G Ptgir prostaglandin I receptor (IP) multiple interactions ISO [cicaprost results in increased activity of PTGIR protein] which results in increased abundance of Calcium CTD PMID:11895442 NCBI chr 7:16,906,490...16,910,905
Ensembl chr 7:16,906,490...16,910,905
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 affects expression ISO Calcium affects the expression of PTGS1 mRNA CTD PMID:15913539 NCBI chr 2:36,216,742...36,258,593
Ensembl chr 2:36,230,426...36,252,272
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO
EXP
Calcium affects the reaction [bisperoxovanadium results in increased expression of PTGS2 mRNA]
Calcium deficiency inhibits the reaction [Serotonin results in increased expression of PTGS2 mRNA]
Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]
CTD PMID:12493747 PMID:19782052 PMID:21262218 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Pth parathyroid hormone multiple interactions
increases stability
increases abundance
decreases abundance
affects metabolic processing
decreases expression
ISO [Calcitriol co-treated with Calcium] results in decreased expression of PTH protein; [Cholecalciferol co-treated with Calcium] results in decreased expression of PTH protein
Calcium deficiency results in increased stability of PTH mRNA
Calcium affects the reaction [Aluminum Compounds results in decreased expression of PTH mRNA]; Calcium affects the reaction [Aluminum Compounds results in decreased secretion of PTH protein]; Calcium affects the reaction [Calcitriol results in decreased expression of PTH mRNA]; Calcium affects the reaction [Calcitriol results in decreased secretion of PTH protein]; Calcium deficiency inhibits the reaction [KHSRP protein binds to PTH 3' UTR]; Calcium deficiency promotes the reaction [HNRNPD protein binds to PTH 3' UTR]
PTH protein modified form results in increased abundance of Calcium
PTH protein results in decreased abundance of Calcium
PTH protein affects the metabolism of Calcium
Calcium results in decreased expression of PTH protein
CTD PMID:80633 PMID:6330156 PMID:15891005 PMID:16094769 PMID:16316325 More... NCBI chr 7:113,385,576...113,388,672
Ensembl chr 7:113,385,580...113,388,570
JBrowse link
G Pth1r parathyroid hormone 1 receptor affects expression ISO Calcium affects the expression of PTH1R mRNA CTD PMID:15913539 NCBI chr 9:110,722,085...110,747,145
Ensembl chr 9:110,722,085...110,747,145
JBrowse link
G Ptk2b PTK2 protein tyrosine kinase 2 beta multiple interactions ISO Calcium affects the reaction [(N)-methanocarba-2MeSADP results in increased phosphorylation of PTK2B protein]
Calcium affects the phosphorylation of and affects the activity of PTK2B protein
CTD PMID:16236484 PMID:16877402 NCBI chr14:66,153,257...66,281,100
Ensembl chr14:66,153,257...66,281,052
JBrowse link
G Ptpn12 protein tyrosine phosphatase, non-receptor type 12 affects expression ISO Calcium affects the expression of PTPN12 mRNA CTD PMID:15913539 NCBI chr 5:20,986,645...21,055,911
Ensembl chr 5:20,986,645...21,055,911
JBrowse link
G Pygl liver glycogen phosphorylase multiple interactions ISO [Phenylephrine co-treated with Calcium] results in increased activity of PYGL protein; Calcium deficiency inhibits the reaction [Calcimycin results in increased activity of PYGL protein]; Glucose inhibits the reaction [[Phenylephrine co-treated with Calcium] results in increased activity of PYGL protein] CTD PMID:747652 PMID:6430282 NCBI chr12:70,190,815...70,227,683
Ensembl chr12:70,190,811...70,231,488
JBrowse link
G Rab7 RAB7, member RAS oncogene family affects expression ISO Calcium affects the expression of RAB7 mRNA CTD PMID:15913539 NCBI chr 6:87,999,106...88,045,270
Ensembl chr 6:87,999,106...88,045,270
JBrowse link
G Ralgds ral guanine nucleotide dissociation stimulator affects expression ISO Calcium affects the expression of RALGDS mRNA CTD PMID:15913539 NCBI chr 2:28,513,089...28,553,082
Ensembl chr 2:28,513,125...28,553,081
JBrowse link
G Rap1a RAS-related protein 1a multiple interactions ISO Calcium promotes the reaction [ibandronic acid results in decreased prenylation of RAP1A protein] CTD PMID:18190680 NCBI chr 3:105,727,260...105,801,394
Ensembl chr 3:105,727,267...105,801,336
JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor (GEF) 3 multiple interactions ISO RAPGEF3 protein promotes the reaction [Benzo(a)pyrene results in increased transport of Calcium] CTD PMID:22167199 NCBI chr15:97,744,770...97,768,419
Ensembl chr15:97,744,770...97,767,972
JBrowse link
G Rbp1 retinol binding protein 1, cellular affects expression ISO Calcium affects the expression of RBP1 mRNA CTD PMID:15913539 NCBI chr 9:98,422,961...98,446,551
Ensembl chr 9:98,422,961...98,446,575
JBrowse link
G Ren1 renin 1 structural decreases secretion
multiple interactions
ISO Calcium results in decreased secretion of REN protein
[[Calcium results in increased activity of MYLK protein] which results in increased phosphorylation of MYL9 protein] which results in decreased secretion of REN protein; ML 7 inhibits the reaction [Calcium results in decreased secretion of REN protein]
CTD PMID:9618396 NCBI chr 1:133,350,674...133,360,320
Ensembl chr 1:133,350,510...133,360,325
JBrowse link
G Rgs4 regulator of G-protein signaling 4 multiple interactions ISO RGS4 protein inhibits the reaction [PTAFR protein affects the localization of and affects the abundance of Calcium] CTD PMID:11297424 NCBI chr 1:169,741,477...169,747,642
Ensembl chr 1:169,741,477...169,747,642
JBrowse link
G Rps3a1 ribosomal protein S3A1 affects expression ISO Calcium affects the expression of RPS3A mRNA CTD PMID:15913539 NCBI chr 3:86,137,940...86,142,668
Ensembl chr 3:86,137,940...86,142,702
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 multiple interactions ISO Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of RPS6KB1 protein]
[Resveratrol results in increased abundance of Calcium] which results in decreased expression of RPS6KB1 protein modified form; dorsomorphin inhibits the reaction [[Resveratrol results in increased abundance of Calcium] which results in decreased expression of RPS6KB1 protein modified form]
CTD PMID:12935885 PMID:23680031 NCBI chr11:86,498,869...86,544,885
Ensembl chr11:86,498,871...86,544,805
JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 multiple interactions ISO [Resveratrol results in increased abundance of Calcium] which results in increased activity of RPTOR protein modified form; dorsomorphin inhibits the reaction [[Resveratrol results in increased abundance of Calcium] which results in increased activity of RPTOR protein modified form] CTD PMID:23680031 NCBI chr11:119,602,905...119,899,591
Ensembl chr11:119,602,905...119,899,576
JBrowse link
G Rraga Ras-related GTP binding A affects expression ISO Calcium affects the expression of RRAGA mRNA CTD PMID:15913539 NCBI chr 4:86,575,673...86,577,285
Ensembl chr 4:86,575,668...86,577,285
JBrowse link
G Ryr1 ryanodine receptor 1, skeletal muscle multiple interactions
affects abundance
increases secretion
increases abundance
ISO [Caffeine results in increased activity of RYR1 protein] which affects the localization of Calcium; [chlorocresol results in increased activity of RYR1 protein] which affects the localization of Calcium; [chlorocresol results in increased activity of RYR1 protein] which results in increased transport of Calcium; [Halothane results in increased activity of RYR1 protein] which affects the localization of Calcium; [RYR1 protein co-treated with 2,3,6,2',3',6'-hexachlorobiphenyl] affects the susceptibility to Calcium; Calcium affects the folding of [CALM1 protein binds to RYR1 protein modified form]; Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]; Dantrolene inhibits the reaction [[chlorocresol results in increased activity of RYR1 protein] which results in increased transport of Calcium]; RYR1 protein polymorphism affects the reaction [Caffeine results in increased secretion of Calcium]; RYR1 protein polymorphism affects the reaction [chlorocresol results in increased secretion of Calcium]
RYR1 protein polymorphism affects the abundance of Calcium
RYR1 protein mutant form results in increased secretion of Calcium
RYR1 gene mutant form results in increased abundance of Calcium
Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]; Calcium affects the reaction [CALM1 protein modified form binds to and affects the activity of RYR1 protein]
CTD PMID:15381065 PMID:15628869 PMID:16372898 PMID:17707769 PMID:18719443 More... NCBI chr 7:29,003,340...29,125,179
Ensembl chr 7:29,003,344...29,125,179
JBrowse link
G Ryr2 ryanodine receptor 2, cardiac multiple interactions ISO FKBP1A protein inhibits the reaction [Calcium results in increased activity of RYR2 protein]
Dantrolene inhibits the reaction [Caffeine promotes the reaction [RYR2 protein results in increased secretion of Calcium]]; HOMER1 protein alternative form inhibits the reaction [Caffeine promotes the reaction [RYR2 protein results in increased secretion of Calcium]]; HOMER1 protein alternative form inhibits the reaction [Cyclic ADP-Ribose promotes the reaction [RYR2 protein results in increased secretion of Calcium]]
CTD PMID:12887973 PMID:17872463 NCBI chr13:11,553,099...12,106,945
Ensembl chr13:11,553,102...12,106,945
JBrowse link
G S100a13 S100 calcium binding protein A13 multiple interactions ISO [Calcium co-treated with Copper] binds to and affects the folding of S100A13 protein; Calcium binds to and affects the folding of S100A13 protein CTD PMID:16766622 NCBI chr 3:90,514,233...90,524,581
Ensembl chr 3:90,514,435...90,524,581
JBrowse link
G S100a2 S100 calcium binding protein A2 affects binding
multiple interactions
ISO Calcium binds to S100A2 protein
[Zinc binds to S100A2 protein] inhibits the reaction [Calcium binds to S100A2 protein]
CTD PMID:17239974 NCBI chr 3:90,590,247...90,591,508
Ensembl chr 3:90,560,363...90,591,531
JBrowse link
G S100a6 S100 calcium binding protein A6 (calcyclin) affects response to substance ISO S100A6 protein affects the susceptibility to Calcium CTD PMID:15068510 NCBI chr 3:90,612,894...90,614,414
Ensembl chr 3:90,612,882...90,624,181
JBrowse link
G S100a8 S100 calcium binding protein A8 (calgranulin A) multiple interactions
affects binding
ISO [Zinc co-treated with Calcium] binds to [S100A8 protein binds to S100A9 protein]
Calcium binds to [S100A8 protein binds to S100A9 protein]
CTD PMID:17050004 NCBI chr 3:90,669,071...90,670,034
Ensembl chr 3:90,668,978...90,670,035
JBrowse link
G S100a9 S100 calcium binding protein A9 (calgranulin B) affects binding
multiple interactions
ISO Calcium binds to [S100A8 protein binds to S100A9 protein]
[Zinc co-treated with Calcium] binds to [S100A8 protein binds to S100A9 protein]
CTD PMID:17050004 NCBI chr 3:90,692,630...90,695,721
Ensembl chr 3:90,692,632...90,695,721
JBrowse link
G S100g S100 calcium binding protein G affects expression ISO Calcium affects the expression of S100G mRNA CTD PMID:15913539 NCBI chr  X:162,961,992...162,964,599
Ensembl chr  X:162,961,992...162,964,599
JBrowse link
G Scgb1a1 secretoglobin, family 1A, member 1 (uteroglobin) increases expression ISO Calcium results in increased expression of SCGB1A1 mRNA; Calcium results in increased expression of SCGB1A1 protein CTD PMID:16237193 NCBI chr19:9,083,642...9,087,956
Ensembl chr19:9,083,636...9,087,958
JBrowse link
G Sct secretin increases abundance ISO SCT protein results in increased abundance of Calcium CTD PMID:1220513 NCBI chr 7:141,278,329...141,279,174
Ensembl chr 7:141,278,330...141,279,133
JBrowse link
G Sec61a1 Sec61 alpha 1 subunit (S. cerevisiae) multiple interactions
increases transport
ISO [HSPA5 protein binds to SEC61A1 protein] which results in decreased transport of Calcium; [SEC61A1 protein results in increased transport of Calcium] which results in increased susceptibility to Thapsigargin; DNAJB11 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium]; DNAJC3 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium] CTD PMID:26085089 NCBI chr 6:88,503,607...88,518,800
Ensembl chr 6:88,503,579...88,518,905
JBrowse link
G Selenot selenoprotein T multiple interactions
affects abundance
ISO Calcium affects the reaction [ADCYAP1 protein results in increased expression of SELENOT mRNA]; SELENOT protein affects the reaction [ADCYAP1 protein results in increased abundance of Calcium]; Thapsigargin promotes the reaction [SELENOT protein affects the abundance of Calcium] CTD PMID:18198219 NCBI chr 3:58,576,636...58,593,544
Ensembl chr 3:58,576,636...58,593,133
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 increases stability ISO Calcium results in increased stability of SERPINE1 protein CTD PMID:21280127 PMID:21280128 NCBI chr 5:137,061,504...137,072,272
Ensembl chr 5:137,061,504...137,072,268
JBrowse link
G Slc12a5 solute carrier family 12, member 5 multiple interactions ISO Calcium affects the reaction [Zinc results in increased activity of SLC12A5 protein] CTD PMID:22441041 NCBI chr 2:164,960,846...164,999,731
Ensembl chr 2:164,960,802...164,999,731
JBrowse link
G Slc23a2 solute carrier family 23 (nucleobase transporters), member 2 decreases expression
multiple interactions
increases expression
EXP Calcium deficiency results in decreased expression of SLC23A2 mRNA
Foscarnet inhibits the reaction [Calcium results in increased expression of SLC23A2 mRNA]; Nifedipine inhibits the reaction [Calcium results in increased expression of SLC23A2 mRNA]
Calcium results in increased expression of SLC23A2 mRNA; Calcium results in increased expression of SLC23A2 protein
CTD PMID:12788230 NCBI chr 2:132,052,496...132,145,320
Ensembl chr 2:132,052,496...132,145,108
JBrowse link
G Slc24a2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 increases uptake ISO SLC24A2 protein results in increased uptake of Calcium CTD PMID:14660663 NCBI chr 4:86,983,124...87,230,652
Ensembl chr 4:86,983,124...87,230,477
JBrowse link
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 multiple interactions ISO Calcium deficiency inhibits the reaction [2,3-dinitrophenol results in increased activity of SLC2A1 protein]; Calcium deficiency inhibits the reaction [Arsenates results in increased activity of SLC2A1 protein]; Calcium deficiency inhibits the reaction [Azides results in increased activity of SLC2A1 protein]; Calcium deficiency inhibits the reaction [INS1 protein results in increased activity of SLC2A1 protein] CTD PMID:10970766 NCBI chr 4:119,108,745...119,137,330
Ensembl chr 4:119,108,711...119,137,983
JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 multiple interactions