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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:alkaline earth metal atom
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Accession:CHEBI:22313 term browser browse the term
Synonyms:related_synonym: Erdalkalimetall;   Erdalkalimetalle;   alkaline-earth metal;   alkaline-earth metals;   metal alcalino-terreux;   metal alcalinoterreo;   metales alcalinoterreos;   metaux alcalino-terreux



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barium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Cartwright blood group) multiple interactions ISO [barium chloride results in increased abundance of Barium] which results in decreased activity of ACHE protein CTD PMID:31407482 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
G ALB albumin multiple interactions
increases secretion
ISO Plant Extracts inhibits the reaction [barium chloride results in increased secretion of ALB protein] CTD PMID:26732703 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G CAT catalase multiple interactions
decreases activity
ISO [barium chloride results in increased abundance of Barium] which results in decreased activity of CAT protein; Plant Extracts inhibits the reaction [barium chloride results in decreased activity of CAT protein] CTD PMID:26732703 PMID:31407482 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G IL1B interleukin 1 beta increases expression
multiple interactions
ISO barium chloride results in increased expression of IL1B mRNA
Plant Extracts inhibits the reaction [barium chloride results in increased expression of IL1B mRNA]
CTD PMID:26732703 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL6 interleukin 6 increases expression
multiple interactions
ISO barium chloride results in increased expression of IL6 mRNA
[barium chloride results in increased abundance of Barium] which results in increased expression of IL6 protein; Plant Extracts inhibits the reaction [barium chloride results in increased expression of IL6 mRNA]
CTD PMID:26732703 PMID:31407482 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 multiple interactions EXP barium chloride results in decreased activity of [KCNQ1 protein binds to KCNE1 protein] CTD PMID:16909339 NCBI chr21:34,446,688...34,512,210
Ensembl chr21:34,446,688...34,512,214
JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 multiple interactions ISO barium chloride inhibits the reaction [KCNJ2 protein results in increased transport of Potassium] CTD PMID:11087224 NCBI chr17:70,169,532...70,180,044
Ensembl chr17:70,168,673...70,180,044
JBrowse link
G KCNK3 potassium two pore domain channel subfamily K member 3 decreases activity ISO barium chloride results in decreased activity of KCNK3 protein CTD PMID:16020457 NCBI chr 2:26,692,722...26,733,420
Ensembl chr 2:26,692,690...26,733,420
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 multiple interactions EXP barium chloride results in decreased activity of [KCNQ1 protein binds to KCNE1 protein] CTD PMID:16909339 NCBI chr11:2,445,008...2,849,110
Ensembl chr11:2,444,684...2,849,105
JBrowse link
G MT1A metallothionein 1A increases expression
multiple interactions
ISO barium chloride results in increased expression of MT1 mRNA
Plant Extracts inhibits the reaction [barium chloride results in increased expression of MT1 mRNA]
CTD PMID:26732703 NCBI chr16:56,638,666...56,640,087
Ensembl chr16:56,638,666...56,640,087
JBrowse link
G MT2A metallothionein 2A increases expression
multiple interactions
ISO barium chloride results in increased expression of MT2A mRNA
Plant Extracts inhibits the reaction [barium chloride results in increased expression of MT2A mRNA]
CTD PMID:26732703 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
JBrowse link
G SERPINE1 serpin family E member 1 increases secretion ISO barium chloride results in increased secretion of SERPINE1 protein CTD PMID:21596853 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G SOD2 superoxide dismutase 2 decreases expression
multiple interactions
ISO barium chloride results in decreased expression of SOD2 mRNA
Plant Extracts inhibits the reaction [barium chloride results in decreased expression of SOD2 mRNA]
CTD PMID:26732703 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G STX1A syntaxin 1A multiple interactions
affects localization
ISO Propofol inhibits the reaction [barium chloride affects the localization of STX1A protein]; STX1A protein modified form inhibits the reaction [Propofol inhibits the reaction [barium chloride affects the localization of STX1A protein]] CTD PMID:29320738 NCBI chr 7:73,699,210...73,719,673
Ensembl chr 7:73,699,206...73,719,672
JBrowse link
G TNF tumor necrosis factor multiple interactions
increases expression
ISO Plant Extracts inhibits the reaction [barium chloride results in increased expression of TNF mRNA] CTD PMID:26732703 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TSC22D3 TSC22 domain family member 3 multiple interactions ISO [barium chloride results in increased abundance of Barium] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:107,713,221...107,777,329
Ensembl chr  X:107,713,221...107,777,342
JBrowse link
barium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMBS hydroxymethylbilane synthase decreases activity ISO Barium ion decreases activity of purified Hmbs protein RGD PMID:6732900 RGD:25394584 NCBI chr11:119,084,864...119,093,549
Ensembl chr11:119,084,866...119,093,549
JBrowse link
barium sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALB albumin increases expression ISO Barium Sulfate results in increased expression of ALB mRNA CTD PMID:29463257 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 increases expression ISO Barium Sulfate results in increased expression of BIRC5 mRNA CTD PMID:29463257 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G CCL11 C-C motif chemokine ligand 11 increases expression ISO Barium Sulfate results in increased expression of CCL11 mRNA CTD PMID:29463257 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334
JBrowse link
G CCL2 C-C motif chemokine ligand 2 increases expression
increases secretion
ISO Barium Sulfate results in increased expression of CCL2 mRNA
Barium Sulfate results in increased secretion of CCL2 protein
CTD PMID:29463257 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
JBrowse link
G CCL20 C-C motif chemokine ligand 20 affects expression ISO Barium Sulfate affects the expression of CCL20 mRNA CTD PMID:29463257 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564
JBrowse link
G CCL22 C-C motif chemokine ligand 22 increases expression ISO Barium Sulfate results in increased expression of CCL22 mRNA CTD PMID:29463257 NCBI chr16:57,358,783...57,366,189
Ensembl chr16:57,358,783...57,366,189
JBrowse link
G CCL24 C-C motif chemokine ligand 24 increases expression ISO Barium Sulfate results in increased expression of CCL24 mRNA CTD PMID:29463257 NCBI chr 7:75,810,825...75,823,372
Ensembl chr 7:75,810,825...75,823,356
JBrowse link
G CCL4 C-C motif chemokine ligand 4 decreases expression ISO Barium Sulfate results in decreased expression of CCL4 mRNA CTD PMID:29463257 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621
JBrowse link
G CCL7 C-C motif chemokine ligand 7 increases expression ISO Barium Sulfate results in increased expression of CCL7 mRNA CTD PMID:29463257 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242
JBrowse link
G CCR2 C-C motif chemokine receptor 2 increases expression ISO Barium Sulfate results in increased expression of CCR2 mRNA CTD PMID:29463257 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940
JBrowse link
G CD40LG CD40 ligand decreases expression ISO Barium Sulfate results in decreased expression of CD40LG mRNA CTD PMID:29463257 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390
JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 increases expression ISO Barium Sulfate results in increased expression of CXCL9 mRNA CTD PMID:29463257 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509
JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 increases expression ISO Barium Sulfate results in increased expression of CXCR3 mRNA CTD PMID:29463257 NCBI chr  X:71,615,913...71,618,515
Ensembl chr  X:71,615,916...71,618,511
JBrowse link
G CYP4A22 cytochrome P450 family 4 subfamily A member 22 increases expression ISO Barium Sulfate results in increased expression of CYP4A1 mRNA CTD PMID:11124224 NCBI chr 1:47,137,441...47,149,738
Ensembl chr 1:47,137,435...47,149,735
JBrowse link
G CYP4F12 cytochrome P450 family 4 subfamily F member 12 increases expression ISO Barium Sulfate results in increased expression of CYP4F1 mRNA CTD PMID:14644421 NCBI chr19:15,673,023...15,698,819
Ensembl chr19:15,673,018...15,697,174
JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 increases expression ISO Barium Sulfate results in increased expression of CYP4F6 mRNA CTD PMID:14644421 NCBI chr19:15,615,207...15,630,639
Ensembl chr19:15,615,218...15,630,639
JBrowse link
G EXO1 exonuclease 1 affects expression ISO Barium Sulfate affects the expression of EXO1 mRNA CTD PMID:29463257 NCBI chr 1:241,847,967...241,889,939
Ensembl chr 1:241,847,967...241,895,148
JBrowse link
G FABP4 fatty acid binding protein 4 decreases expression ISO Barium Sulfate results in decreased expression of FABP4 mRNA CTD PMID:29463257 NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236
JBrowse link
G HBA1 hemoglobin subunit alpha 1 decreases expression ISO Barium Sulfate results in decreased expression of HBA1 mRNA CTD PMID:29463257 NCBI chr16:176,680...177,522
Ensembl chr16:176,680...177,522
JBrowse link
G IL2RB interleukin 2 receptor subunit beta decreases expression ISO Barium Sulfate results in decreased expression of IL2RB mRNA CTD PMID:29463257 NCBI chr22:37,125,838...37,175,118
Ensembl chr22:37,125,843...37,175,054
JBrowse link
G IL6 interleukin 6 increases expression EXP Barium Sulfate results in increased expression of IL6 protein CTD PMID:11403239 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G KRT1 keratin 1 increases expression ISO Barium Sulfate results in increased expression of KRT1 mRNA CTD PMID:29463257 NCBI chr12:52,674,736...52,680,407
Ensembl chr12:52,674,736...52,680,407
JBrowse link
G LIG4 DNA ligase 4 increases expression ISO Barium Sulfate results in increased expression of LIG4 mRNA CTD PMID:29463257 NCBI chr13:108,207,442...108,218,349
Ensembl chr13:108,207,439...108,218,368
JBrowse link
G LPO lactoperoxidase increases expression ISO Barium Sulfate results in increased expression of LPO mRNA; Barium Sulfate results in increased expression of LPO protein CTD PMID:29463257 NCBI chr17:58,238,550...58,268,518
Ensembl chr17:58,218,548...58,268,518
JBrowse link
G MMP12 matrix metallopeptidase 12 increases expression ISO Barium Sulfate results in increased expression of MMP12 mRNA; Barium Sulfate results in increased expression of MMP12 protein CTD PMID:29463257 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982
JBrowse link
G MUTYH mutY DNA glycosylase increases expression ISO Barium Sulfate results in increased expression of MUTYH mRNA CTD PMID:29463257 NCBI chr 1:45,329,242...45,340,447
Ensembl chr 1:45,329,163...45,340,893
JBrowse link
G NGB neuroglobin decreases expression ISO Barium Sulfate results in decreased expression of NGB mRNA CTD PMID:29463257 NCBI chr14:77,265,483...77,271,206
Ensembl chr14:77,265,483...77,271,206
JBrowse link
G NOXO1 NADPH oxidase organizer 1 increases expression ISO Barium Sulfate results in increased expression of NOXO1 mRNA CTD PMID:29463257 NCBI chr16:1,978,917...1,984,027
Ensembl chr16:1,978,917...1,984,192
JBrowse link
G OPCML opioid binding protein/cell adhesion molecule like increases expression ISO Barium Sulfate results in increased expression of OPCML mRNA CTD PMID:29463257 NCBI chr11:132,403,361...133,532,534
Ensembl chr11:132,414,977...133,532,501
JBrowse link
G PF4 platelet factor 4 increases expression ISO Barium Sulfate results in increased expression of PF4 mRNA CTD PMID:29463257 NCBI chr 4:73,980,811...73,982,124
Ensembl chr 4:73,980,811...73,982,027
JBrowse link
G SCD stearoyl-CoA desaturase affects expression ISO Barium Sulfate affects the expression of SCD1 mRNA CTD PMID:29463257 NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826
JBrowse link
G TCF21 transcription factor 21 decreases expression ISO Barium Sulfate results in decreased expression of TCF21 mRNA CTD PMID:29463257 NCBI chr 6:133,889,113...133,895,537
Ensembl chr 6:133,889,113...133,895,553
JBrowse link
G THBS2 thrombospondin 2 increases expression ISO Barium Sulfate results in increased expression of THBS2 mRNA CTD PMID:29463257 NCBI chr 6:169,215,785...169,253,846
Ensembl chr 6:169,215,780...169,254,050
JBrowse link
G TOP2A DNA topoisomerase II alpha increases expression ISO Barium Sulfate results in increased expression of TOP2A mRNA CTD PMID:29463257 NCBI chr17:40,388,525...40,417,902
Ensembl chr17:40,388,525...40,417,896
JBrowse link
G TXNIP thioredoxin interacting protein decreases expression ISO Barium Sulfate results in decreased expression of TXNIP mRNA CTD PMID:29463257 NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579
JBrowse link
G XRCC2 X-ray repair cross complementing 2 increases expression ISO Barium Sulfate results in increased expression of XRCC2 mRNA CTD PMID:29463257 NCBI chr 7:152,644,776...152,676,141
Ensembl chr 7:152,644,776...152,676,141
JBrowse link
barium(0) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Cartwright blood group) multiple interactions ISO [barium chloride results in increased abundance of Barium] which results in decreased activity of ACHE protein CTD PMID:31407482 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
G ADRA1A adrenoceptor alpha 1A multiple interactions ISO ADRA1A protein promotes the reaction [TRPC6 protein results in increased transport of Barium] CTD PMID:11179201 NCBI chr 8:26,738,113...26,870,994
Ensembl chr 8:26,748,150...26,867,278
JBrowse link
G CACNA1A calcium voltage-gated channel subunit alpha1 A increases transport ISO CACNA1A protein results in increased transport of Barium CTD PMID:11313431 NCBI chr19:13,206,442...13,506,479
Ensembl chr19:13,206,442...13,633,025
JBrowse link
G CACNA1B calcium voltage-gated channel subunit alpha1 B affects transport
increases transport
multiple interactions
EXP CACNA1B gene polymorphism affects the transport of Barium
CACNA1B protein results in increased transport of Barium
[GNB1 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB1 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB1 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB5 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; Cadmium Chloride inhibits the reaction [CACNA1B protein results in increased transport of Barium]
CTD PMID:11007869 PMID:11756491 PMID:14559144 NCBI chr 9:137,877,782...138,124,619
Ensembl chr 9:137,877,782...138,124,624
JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C increases transport ISO CACNA1C protein results in increased transport of Barium CTD PMID:17569661 NCBI chr12:1,969,552...2,697,950
Ensembl chr12:1,970,772...2,697,950
JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D affects transport
multiple interactions
increases transport
ISO CACNA1D protein affects the transport of Barium
CACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Barium]
CACNA1D protein results in increased transport of Barium
CTD PMID:15357422 PMID:17567805 PMID:27798183 NCBI chr 3:53,494,611...53,813,733
Ensembl chr 3:53,328,963...53,813,733
JBrowse link
G CACNA1E calcium voltage-gated channel subunit alpha1 E increases transport
multiple interactions
affects transport
EXP
ISO
CACNA1E mRNA alternative form results in increased transport of Barium; CACNA1E protein results in increased transport of Barium
1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid affects the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; 4-O-methyl-12-O-tetradecanoylphorbol 13-acetate affects the reaction [CACNA1E protein results in increased transport of Barium]; Atropine inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; Calcium inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; Heparin affects the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; Isradipine inhibits the reaction [CACNA1E protein results in increased transport of Barium]; Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]; Nickel inhibits the reaction [CACNA1E protein results in increased transport of Barium]; omega-conotoxin-MVIIC promotes the reaction [Isradipine inhibits the reaction [CACNA1E protein results in increased transport of Barium]]; Ro 31-8425 inhibits the reaction [4-O-methyl-12-O-tetradecanoylphorbol 13-acetate affects the reaction [CACNA1E protein results in increased transport of Barium]]; Ro 31-8425 inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; SNX 482 inhibits the reaction [CACNA1E protein results in increased transport of Barium]
SNX 482 inhibits the reaction [CACNA1E mRNA alternative form results in increased transport of Barium]
CACNA1E protein affects the transport of Barium
CTD PMID:10627594 PMID:10669483 PMID:11102459 PMID:11179973 PMID:12663092 More... NCBI chr 1:181,317,712...181,808,084
Ensembl chr 1:181,317,690...181,808,084
JBrowse link
G CACNA1F calcium voltage-gated channel subunit alpha1 F multiple interactions
increases transport
ISO 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester promotes the reaction [CACNA1F protein results in increased transport of Barium]; Diltiazem inhibits the reaction [CACNA1F protein results in increased transport of Barium]; Isradipine inhibits the reaction [CACNA1F protein results in increased transport of Barium]; Verapamil inhibits the reaction [CACNA1F protein results in increased transport of Barium] CTD PMID:14744918 NCBI chr  X:49,205,063...49,233,404
Ensembl chr  X:49,205,063...49,233,371
JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G increases transport
multiple interactions
EXP CACNA1G mRNA alternative form results in increased transport of Barium; CACNA1G protein results in increased transport of Barium
Cerium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Erbium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Gadolinium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Holmium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Lanthanum inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Neodymium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Scandium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Ytterbium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Yttrium inhibits the reaction [CACNA1G protein results in increased transport of Barium]
CTD PMID:11179973 PMID:12163980 NCBI chr17:50,560,715...50,629,625
Ensembl chr17:50,560,715...50,627,474
JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H increases transport EXP CACNA1H mRNA alternative form results in increased transport of Barium CTD PMID:11179973 NCBI chr16:1,153,106...1,221,769
Ensembl chr16:1,153,106...1,221,771
JBrowse link
G CACNA1I calcium voltage-gated channel subunit alpha1 I increases transport EXP CACNA1I mRNA alternative form results in increased transport of Barium CTD PMID:11179973 NCBI chr22:39,570,753...39,689,737
Ensembl chr22:39,570,753...39,689,735
JBrowse link
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 affects transport
increases transport
EXP
ISO
CACNA2D1 protein affects the transport of Barium
CACNA2D1 protein results in increased transport of Barium
CTD PMID:11313431 PMID:15245474 PMID:15474003 NCBI chr 7:81,946,444...82,443,956
Ensembl chr 7:81,946,444...82,443,777
JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 multiple interactions ISO CACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Barium] CTD PMID:27798183 NCBI chr 3:50,362,613...50,504,244
Ensembl chr 3:50,362,613...50,504,244
JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 affects transport EXP CACNB3 protein affects the transport of Barium CTD PMID:15245474 NCBI chr12:48,814,432...48,828,941
Ensembl chr12:48,813,794...48,828,941
JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 affects transport EXP
ISO
CACNB4 protein affects the transport of Barium CTD PMID:11313431 PMID:15245474 NCBI chr 2:151,832,771...152,099,167
Ensembl chr 2:151,832,771...152,099,167
JBrowse link
G CACNG2 calcium voltage-gated channel auxiliary subunit gamma 2 affects transport EXP CACNG2 protein affects the transport of Barium CTD PMID:11313431 NCBI chr22:36,560,857...36,703,752
Ensembl chr22:36,560,857...36,703,752
JBrowse link
G CACNG3 calcium voltage-gated channel auxiliary subunit gamma 3 affects transport EXP CACNG3 protein affects the transport of Barium CTD PMID:11313431 NCBI chr16:24,256,335...24,362,412
Ensembl chr16:24,256,335...24,362,412
JBrowse link
G CAT catalase multiple interactions ISO [barium chloride results in increased abundance of Barium] which results in decreased activity of CAT protein CTD PMID:31407482 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CHRNA2 cholinergic receptor nicotinic alpha 2 subunit multiple interactions EXP 1-Butanol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 1-Propanol promotes the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 2-butanol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 2-Propanol promotes the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; [CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium; Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]; crotonyl alcohol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; isobutyl alcohol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; n-pentanol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; tert-Butyl Alcohol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]] CTD PMID:11821649 NCBI chr 8:27,459,756...27,479,285
Ensembl chr 8:27,459,756...27,479,883
JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO [CHRNA4 protein co-treated with CHRNB2 protein] affects the reaction [Barium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein mutant form co-treated with CHRNB2 protein] inhibits the reaction [Barium results in increased susceptibility to Acetylcholine] CTD PMID:12754307 NCBI chr20:63,343,223...63,375,471
Ensembl chr20:63,343,223...63,378,401
JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO [CHRNA4 protein co-treated with CHRNB2 protein] affects the reaction [Barium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein mutant form co-treated with CHRNB2 protein] inhibits the reaction [Barium results in increased susceptibility to Acetylcholine] CTD PMID:12754307 NCBI chr 1:154,567,778...154,584,708
Ensembl chr 1:154,567,778...154,580,013
JBrowse link
G CHRNB4 cholinergic receptor nicotinic beta 4 subunit multiple interactions EXP 1-Butanol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 1-Propanol promotes the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 2-butanol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 2-Propanol promotes the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; [CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium; Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]; crotonyl alcohol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; isobutyl alcohol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; n-pentanol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; tert-Butyl Alcohol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]] CTD PMID:11821649 NCBI chr15:78,623,282...78,655,586
Ensembl chr15:78,624,111...78,727,754
JBrowse link
G DRD2 dopamine receptor D2 multiple interactions
decreases transport
ISO 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester inhibits the reaction [DRD2 protein results in decreased transport of Barium]; [DRD2 protein affects the abundance of Calcium] which results in decreased transport of Barium; [DRD2 protein results in increased activity of PLCB1 protein] which results in decreased transport of Barium; DRD2 protein affects the reaction [N-n-propylnorapomorphine analog results in decreased transport of Barium]; DRD2 protein affects the reaction [Quinpirole results in decreased transport of Barium]; Nifedipine inhibits the reaction [DRD2 protein affects the reaction [Quinpirole results in decreased transport of Barium]] CTD PMID:11124974 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G F2 coagulation factor II, thrombin increases uptake
multiple interactions
EXP F2 protein results in increased uptake of Barium
Nickel inhibits the reaction [F2 protein results in increased uptake of Barium]
CTD PMID:2125206 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F2RL1 F2R like trypsin receptor 1 multiple interactions EXP Barium inhibits the reaction [F2RL1 protein results in increased transport of Chlorides]; F2RL1 protein affects the reaction [1-oleoyl-2-acetoyl-sn-glycerol results in increased transport of Barium] CTD PMID:11804840 PMID:16123040 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315
JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 decreases activity EXP Barium results in decreased activity of FXYD2 protein CTD PMID:11533133 NCBI chr11:117,820,057...117,828,089
Ensembl chr11:117,800,844...117,828,698
JBrowse link
G GNB1 G protein subunit beta 1 multiple interactions EXP [GNB1 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB1 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB1 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr 1:1,785,286...1,891,087
Ensembl chr 1:1,785,285...1,891,117
JBrowse link
G GNB2 G protein subunit beta 2 multiple interactions EXP [GNB2 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr 7:100,673,740...100,679,169
Ensembl chr 7:100,673,567...100,679,174
JBrowse link
G GNB3 G protein subunit beta 3 multiple interactions EXP [GNB3 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr12:6,840,922...6,847,393
Ensembl chr12:6,839,954...6,847,393
JBrowse link
G GNB4 G protein subunit beta 4 multiple interactions EXP [GNB4 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr 3:179,396,088...179,451,470
Ensembl chr 3:179,396,088...179,451,476
JBrowse link
G GNB5 G protein subunit beta 5 multiple interactions EXP [GNB5 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr15:52,115,100...52,191,392
Ensembl chr15:52,115,100...52,191,392
JBrowse link
G GNG2 G protein subunit gamma 2 multiple interactions EXP [GNB1 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB5 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr14:51,826,174...51,969,800
Ensembl chr14:51,826,195...51,979,342
JBrowse link
G GNG3 G protein subunit gamma 3 multiple interactions EXP [GNB1 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr11:62,707,255...62,709,206
Ensembl chr11:62,707,676...62,709,201
JBrowse link
G GNGT1 G protein subunit gamma transducin 1 multiple interactions EXP [GNB1 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr 7:93,906,567...93,911,265
Ensembl chr 7:93,591,573...93,911,265
JBrowse link
G IL6 interleukin 6 multiple interactions ISO [barium chloride results in increased abundance of Barium] which results in increased expression of IL6 protein CTD PMID:31407482 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G KCNA10 potassium voltage-gated channel subfamily A member 10 multiple interactions EXP Barium inhibits the reaction [KCNA10 protein results in increased transport of Potassium] CTD PMID:10836990 NCBI chr 1:110,517,217...110,519,175
Ensembl chr 1:110,517,217...110,519,175
JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 multiple interactions EXP Barium results in decreased activity of [KCNQ1 protein binds to KCNE1 protein] CTD PMID:16909339 NCBI chr21:34,446,688...34,512,210
Ensembl chr21:34,446,688...34,512,214
JBrowse link
G KCNH1 potassium voltage-gated channel subfamily H member 1 decreases activity EXP Barium results in decreased activity of KCNH1 protein CTD PMID:10896755 NCBI chr 1:210,678,314...211,134,148
Ensembl chr 1:210,676,823...211,134,165
JBrowse link
G KCNH3 potassium voltage-gated channel subfamily H member 3 multiple interactions EXP Barium binds to and results in decreased activity of KCNH3 protein CTD PMID:12193184 NCBI chr12:49,538,541...49,558,337
Ensembl chr12:49,539,030...49,558,337
JBrowse link
G KCNJ10 potassium inwardly rectifying channel subfamily J member 10 decreases activity ISO Barium results in decreased activity of KCNJ10 protein CTD PMID:16331678 PMID:17978865 NCBI chr 1:160,037,467...160,070,160
Ensembl chr 1:159,998,651...160,070,160
JBrowse link
G KCNJ12 potassium inwardly rectifying channel subfamily J member 12 multiple interactions EXP Barium inhibits the reaction [KCNJ12 protein results in increased transport of Potassium] CTD PMID:15958527 NCBI chr17:21,376,357...21,419,870
Ensembl chr17:21,376,357...21,419,870
JBrowse link
G KCNJ14 potassium inwardly rectifying channel subfamily J member 14 multiple interactions EXP
ISO
Barium inhibits the reaction [KCNJ14 protein results in increased transport of Potassium] CTD PMID:10938328 PMID:17347781 NCBI chr19:48,455,574...48,466,980
Ensembl chr19:48,455,574...48,466,980
JBrowse link
G KCNJ15 potassium inwardly rectifying channel subfamily J member 15 decreases activity EXP Barium results in decreased activity of KCNJ15 protein CTD PMID:15328350 NCBI chr21:38,229,926...38,307,357
Ensembl chr21:38,155,549...38,307,357
JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 multiple interactions
decreases activity
EXP
ISO
Barium inhibits the reaction [KCNJ2 protein results in increased transport of Potassium]
Barium results in decreased activity of KCNJ2 protein
CTD PMID:12598232 PMID:15958527 PMID:17347781 PMID:17699636 NCBI chr17:70,169,532...70,180,044
Ensembl chr17:70,168,673...70,180,044
JBrowse link
G KCNJ4 potassium inwardly rectifying channel subfamily J member 4 decreases activity
multiple interactions
EXP
ISO
Barium results in decreased activity of KCNJ4 protein
Barium inhibits the reaction [KCNJ4 protein results in increased transport of Potassium]
CTD PMID:12598232 PMID:17091215 NCBI chr22:38,426,327...38,455,199
Ensembl chr22:38,426,327...38,455,199
JBrowse link
G KCNK1 potassium two pore domain channel subfamily K member 1 multiple interactions ISO Barium inhibits the reaction [KCNK1 protein results in increased transport of Potassium]; Barium inhibits the reaction [KCNK1 protein results in increased transport of Sodium] CTD PMID:16847696 NCBI chr 1:233,614,106...233,672,514
Ensembl chr 1:233,614,106...233,672,514
JBrowse link
G KCNK18 potassium two pore domain channel subfamily K member 18 multiple interactions EXP Barium inhibits the reaction [KCNK18 protein results in increased transport of Potassium] CTD PMID:12754259 NCBI chr10:117,197,489...117,210,299
Ensembl chr10:117,197,489...117,210,299
JBrowse link
G KCNK9 potassium two pore domain channel subfamily K member 9 multiple interactions ISO Barium inhibits the reaction [KCNK9 protein results in increased transport of Potassium] CTD PMID:10734076 NCBI chr 8:139,600,838...139,703,135
Ensembl chr 8:139,600,838...139,704,109
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 multiple interactions EXP Barium results in decreased activity of [KCNQ1 protein binds to KCNE1 protein] CTD PMID:16909339 NCBI chr11:2,445,008...2,849,110
Ensembl chr11:2,444,684...2,849,105
JBrowse link
G MIR30A microRNA 30a multiple interactions EXP [Air Pollutants, Occupational results in increased abundance of Barium] which results in decreased expression of MIR30A mRNA CTD PMID:27506416 NCBI chr 6:71,403,551...71,403,621
Ensembl chr 6:71,403,551...71,403,621
JBrowse link
G MMP14 matrix metallopeptidase 14 increases expression EXP Barium results in increased expression of MMP14 protein CTD PMID:23804419 NCBI chr14:22,836,585...22,847,758
Ensembl chr14:22,836,560...22,849,041
JBrowse link
G NPR3 natriuretic peptide receptor 3 multiple interactions EXP Barium inhibits the reaction [NPR3 protein affects the reaction [Enterotoxins affects the transport of Potassium]]; Barium inhibits the reaction [NPR3 protein affects the reaction [guanylin affects the transport of Potassium]] CTD PMID:11889121 NCBI chr 5:32,689,076...32,791,720
Ensembl chr 5:32,689,070...32,791,724
JBrowse link
G P2RX7 purinergic receptor P2X 7 multiple interactions EXP P2RX7 protein affects the reaction [Adenosine Triphosphate results in increased transport of Barium] CTD PMID:11003599 NCBI chr12:121,132,819...121,188,032
Ensembl chr12:121,132,819...121,188,032
JBrowse link
G PLCB1 phospholipase C beta 1 multiple interactions ISO [DRD2 protein results in increased activity of PLCB1 protein] which results in decreased transport of Barium CTD PMID:11124974 NCBI chr20:8,132,266...8,884,900
Ensembl chr20:8,077,251...8,968,360
JBrowse link
G PTK2 protein tyrosine kinase 2 increases phosphorylation EXP Barium results in increased phosphorylation of PTK2 protein CTD PMID:23804419 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216
JBrowse link
G SGK1 serum/glucocorticoid regulated kinase 1 multiple interactions EXP Barium inhibits the reaction [SGK1 protein results in increased transport of Potassium] CTD PMID:12590200 NCBI chr 6:134,169,248...134,318,112
Ensembl chr 6:134,169,248...134,318,112
JBrowse link
G SGK2 serum/glucocorticoid regulated kinase 2 multiple interactions EXP Barium inhibits the reaction [SGK2 protein results in increased transport of Potassium] CTD PMID:12590200 NCBI chr20:43,559,027...43,585,627
Ensembl chr20:43,558,968...43,588,237
JBrowse link
G SGK3 serum/glucocorticoid regulated kinase family member 3 multiple interactions EXP Barium inhibits the reaction [SGK3 protein results in increased transport of Potassium] CTD PMID:12590200 NCBI chr 8:66,712,781...66,862,022
Ensembl chr 8:66,712,734...66,862,022
JBrowse link
G SLC12A4 solute carrier family 12 member 4 multiple interactions ISO Barium inhibits the reaction [SLC12A4 protein results in increased transport of Potassium] CTD PMID:11703599 NCBI chr16:67,943,474...67,968,694
Ensembl chr16:67,943,474...67,969,601
JBrowse link
G SLC12A7 solute carrier family 12 member 7 decreases activity ISO Barium results in decreased activity of SLC12A7 protein CTD PMID:10913127 NCBI chr 5:1,050,384...1,155,887
Ensembl chr 5:1,050,384...1,112,063
JBrowse link
G SLC22A12 solute carrier family 22 member 12 multiple interactions ISO Barium promotes the reaction [SLC22A12 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:15284287 NCBI chr11:64,591,219...64,603,250
Ensembl chr11:64,590,641...64,602,353
JBrowse link
G SLC22A3 solute carrier family 22 member 3 multiple interactions ISO Barium inhibits the reaction [SLC22A3 protein results in increased uptake of Tetraethylammonium] CTD PMID:10966924 NCBI chr 6:160,348,378...160,454,982
Ensembl chr 6:160,348,378...160,452,577
JBrowse link
G SLC8A1 solute carrier family 8 member A1 affects transport ISO SLC8A1 protein affects the transport of Barium CTD PMID:17560225 NCBI chr 2:40,097,270...40,512,435
Ensembl chr 2:40,097,270...40,611,053
JBrowse link
G TNF tumor necrosis factor multiple interactions ISO Barium inhibits the reaction [TNF protein results in increased transport of Potassium] CTD PMID:10783394 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TRPC3 transient receptor potential cation channel subfamily C member 3 multiple interactions
increases transport
EXP
ISO
1-oleoyl-2-acetylglycerol promotes the reaction [TRPC3 protein results in increased transport of Barium]
1-oleoyl-2-acetoyl-sn-glycerol affects the reaction [TRPC3 protein results in increased transport of Barium]
CTD PMID:11042129 PMID:16055711 NCBI chr 4:121,874,481...121,952,060
Ensembl chr 4:121,874,481...121,952,060
JBrowse link
G TRPC4 transient receptor potential cation channel subfamily C member 4 multiple interactions
increases transport
EXP TRPC4 protein affects the reaction [Carbachol results in increased transport of Barium]
TRPC4 protein results in increased transport of Barium
CTD PMID:11042129 PMID:11830588 NCBI chr13:37,632,063...37,869,772
Ensembl chr13:37,632,063...37,869,802
JBrowse link
G TRPC6 transient receptor potential cation channel subfamily C member 6 multiple interactions
increases transport
affects transport
ISO 1-oleoyl-2-acetoyl-sn-glycerol affects the reaction [TRPC6 protein affects the transport of Barium]; ADRA1A protein promotes the reaction [TRPC6 protein results in increased transport of Barium] CTD PMID:11179201 PMID:16055711 NCBI chr11:101,451,470...101,584,007
Ensembl chr11:101,451,564...101,872,562
JBrowse link
G TRPM6 transient receptor potential cation channel subfamily M member 6 multiple interactions EXP TRPM6 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Barium]; TRPM6 protein affects the reaction [1-stearoyl-2-arachidonoylglycerol results in increased transport of Barium] CTD PMID:11988098 NCBI chr 9:74,722,495...74,887,921
Ensembl chr 9:74,722,495...74,888,094
JBrowse link
G TRPV6 transient receptor potential cation channel subfamily V member 6 increases uptake EXP TRPV6 protein results in increased uptake of Barium CTD PMID:19996302 PMID:21146870 NCBI chr 7:142,871,208...142,885,745
Ensembl chr 7:142,871,208...142,885,745
JBrowse link
G TSC22D3 TSC22 domain family member 3 multiple interactions ISO [barium chloride results in increased abundance of Barium] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:107,713,221...107,777,329
Ensembl chr  X:107,713,221...107,777,342
JBrowse link
G UROD uroporphyrinogen decarboxylase affects abundance EXP UROD protein affects the abundance of Barium CTD PMID:16325539 NCBI chr 1:45,012,254...45,015,575
Ensembl chr 1:45,010,950...45,015,575
JBrowse link
beryllium atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN2A cyclin dependent kinase inhibitor 2A multiple interactions ISO [Beryllium results in increased methylation of CDKN2A promoter] which results in decreased expression of CDKN2A mRNA CTD PMID:11872642 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
JBrowse link
G ESR1 estrogen receptor 1 increases methylation ISO Beryllium results in increased methylation of ESR1 gene CTD PMID:11872642 NCBI chr 6:151,654,148...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 affects binding
increases response to substance
EXP HLA-DPB1 protein mutant form binds to Beryllium
HLA-DPB1 gene polymorphism results in increased susceptibility to Beryllium; HLA-DPB1 gene SNP results in increased susceptibility to Beryllium; HLA-DPB1 protein mutant form results in increased susceptibility to Beryllium
CTD PMID:11551429 PMID:15273960 PMID:17956852 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,990...33,089,696
JBrowse link
G HRAS HRas proto-oncogene, GTPase increases mutagenesis ISO Beryllium results in increased mutagenesis of HRAS gene CTD PMID:7545909 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321
JBrowse link
G IL1B interleukin 1 beta increases expression
affects expression
EXP Beryllium results in increased expression of IL1B mRNA
Beryllium affects the expression of IL1B mRNA
CTD PMID:8473757 PMID:8629860 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G TNF tumor necrosis factor increases response to substance
increases secretion
increases expression
EXP TNF promoter polymorphism results in increased susceptibility to Beryllium
Beryllium results in increased secretion of TNF protein
Beryllium results in increased expression of TNF mRNA
CTD PMID:8629860 PMID:12449171 PMID:15127972 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
beryllium dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 affects expression ISO beryllium chloride affects the expression of APEX1 mRNA CTD PMID:23793613 NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772
JBrowse link
G OGG1 8-oxoguanine DNA glycosylase affects expression ISO beryllium chloride affects the expression of OGG1 mRNA CTD PMID:23793613 NCBI chr 3:9,749,952...9,788,246
Ensembl chr 3:9,749,944...9,788,219
JBrowse link
G TP53 tumor protein p53 increases expression ISO beryllium chloride results in increased expression of TRP53 mRNA CTD PMID:23793613 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
beryllium difluoride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions EXP beryllium fluoride promotes the reaction [ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate] CTD PMID:11027628 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCC6 ATP binding cassette subfamily C member 6 multiple interactions ISO beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]; Cobalt promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]]; Magnesium Chloride promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]]; Manganese promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]]; Nickel promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]] CTD PMID:12069597 NCBI chr16:16,149,565...16,223,617
Ensembl chr16:16,149,565...16,223,522
JBrowse link
G ABCC8 ATP binding cassette subfamily C member 8 decreases activity EXP
ISO
beryllium fluoride results in decreased activity of ABCC8 protein CTD PMID:17561960 PMID:18025464 NCBI chr11:17,392,498...17,476,849
Ensembl chr11:17,392,498...17,476,894
JBrowse link
G CREB1 cAMP responsive element binding protein 1 increases expression ISO beryllium fluoride results in increased expression of CREB1 protein CTD PMID:11867686 NCBI chr 2:207,529,943...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO beryllium fluoride results in increased expression of FOS protein CTD PMID:11867686 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 increases phosphorylation ISO beryllium fluoride results in increased phosphorylation of MAP2K1 protein CTD PMID:11867686 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,544
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 increases phosphorylation ISO beryllium fluoride results in increased phosphorylation of MAPK3 protein CTD PMID:11867686 NCBI chr16:30,114,105...30,123,309
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor increases expression ISO beryllium fluoride results in increased expression of MYC protein CTD PMID:11867686 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
beryllium dihydride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN2A cyclin dependent kinase inhibitor 2A multiple interactions ISO [Beryllium results in increased methylation of CDKN2A promoter] which results in decreased expression of CDKN2A mRNA CTD PMID:11872642 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
JBrowse link
G ESR1 estrogen receptor 1 increases methylation ISO Beryllium results in increased methylation of ESR1 gene CTD PMID:11872642 NCBI chr 6:151,654,148...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 increases response to substance
affects binding
EXP HLA-DPB1 gene polymorphism results in increased susceptibility to Beryllium; HLA-DPB1 gene SNP results in increased susceptibility to Beryllium; HLA-DPB1 protein mutant form results in increased susceptibility to Beryllium
HLA-DPB1 protein mutant form binds to Beryllium
CTD PMID:11551429 PMID:15273960 PMID:17956852 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,990...33,089,696
JBrowse link
G HRAS HRas proto-oncogene, GTPase increases mutagenesis ISO Beryllium results in increased mutagenesis of HRAS gene CTD PMID:7545909 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321
JBrowse link
G IL1B interleukin 1 beta increases expression
affects expression
EXP Beryllium results in increased expression of IL1B mRNA
Beryllium affects the expression of IL1B mRNA
CTD PMID:8473757 PMID:8629860 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G TNF tumor necrosis factor increases expression
increases response to substance
increases secretion
EXP Beryllium results in increased expression of TNF mRNA
TNF promoter polymorphism results in increased susceptibility to Beryllium
Beryllium results in increased secretion of TNF protein
CTD PMID:8629860 PMID:12449171 PMID:15127972 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
beryllium sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTA2 actin alpha 2, smooth muscle increases expression EXP beryllium sulfate results in increased expression of ACTA2 mRNA CTD PMID:16314022 NCBI chr10:88,935,074...88,991,397
Ensembl chr10:88,935,074...88,991,339
JBrowse link
G ANXA5 annexin A5 increases expression EXP beryllium sulfate results in increased expression of ANXA5 mRNA CTD PMID:16314022 NCBI chr 4:121,667,946...121,696,994
Ensembl chr 4:121,667,946...121,696,995
JBrowse link
G CCL3 C-C motif chemokine ligand 3 multiple interactions
increases secretion
EXP beryllium sulfate promotes the reaction [RUNX1 protein binds to CCL3 promoter]
beryllium sulfate results in increased secretion of CCL3 mRNA
CTD PMID:16314022 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
JBrowse link
G CCL4 C-C motif chemokine ligand 4 increases secretion EXP beryllium sulfate results in increased secretion of CCL4 mRNA CTD PMID:16314022 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621
JBrowse link
G CCL5 C-C motif chemokine ligand 5 increases expression EXP beryllium sulfate results in increased expression of CCL5 mRNA CTD PMID:16314022 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CD44 CD44 molecule (Indian blood group) increases expression EXP beryllium sulfate results in increased expression of CD44 mRNA CTD PMID:16314022 NCBI chr11:35,139,168...35,232,402
Ensembl chr11:35,138,882...35,232,402
JBrowse link
G CD86 CD86 molecule increases expression EXP beryllium sulfate results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A multiple interactions
increases expression
EXP beryllium sulfate promotes the reaction [TP53 protein binds to CDKN1A promoter]
beryllium sulfate results in increased expression of CDKN1A mRNA; beryllium sulfate results in increased expression of CDKN1A protein
CTD PMID:17395767 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A increases expression EXP beryllium sulfate results in increased expression of CDKN2A mRNA; beryllium sulfate results in increased expression of CDKN2A protein CTD PMID:17395767 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions ISO [beryllium sulfate co-treated with IFNG protein] results in increased expression of CREB1 protein CTD PMID:10755711 NCBI chr 2:207,529,943...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CTSL cathepsin L increases expression EXP beryllium sulfate results in increased expression of CTSL mRNA CTD PMID:16314022 NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469
JBrowse link
G CTSV cathepsin V increases expression EXP beryllium sulfate results in increased expression of CTSV mRNA CTD PMID:16314022 NCBI chr 9:97,029,677...97,039,643
Ensembl chr 9:97,029,677...97,156,556
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 increases secretion EXP beryllium sulfate results in increased secretion of CXCL1 mRNA CTD PMID:16314022 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
JBrowse link
G CXCL3 C-X-C motif chemokine ligand 3 increases expression EXP beryllium sulfate results in increased expression of CXCL3 mRNA CTD PMID:16314022 NCBI chr 4:74,036,589...74,038,689
Ensembl chr 4:74,036,589...74,038,807
JBrowse link
G EGR2 early growth response 2 increases expression EXP beryllium sulfate results in increased expression of EGR2 mRNA CTD PMID:16314022 NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,919,900
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO beryllium sulfate results in increased expression of FOS mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]; Dactinomycin inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]; Ro 31-8220 inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]
CTD PMID:11568973 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G HLA-A major histocompatibility complex, class I, A increases expression EXP beryllium sulfate results in increased expression of HLA-A mRNA CTD PMID:16314022 NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,945,884
JBrowse link
G HLA-C major histocompatibility complex, class I, C increases expression EXP beryllium sulfate results in increased expression of HLA-C mRNA CTD PMID:16314022 NCBI chr 6:31,268,749...31,272,092
Ensembl chr 6:31,268,749...31,272,130
JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 affects binding EXP beryllium sulfate binds to HLA-DPB1 protein CTD PMID:11423174 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,990...33,089,696
JBrowse link
G HLA-DPB2 major histocompatibility complex, class II, DP beta 2 (pseudogene) increases response to substance EXP HLA-DPB2 protein mutant form results in increased susceptibility to beryllium sulfate CTD PMID:16272364 NCBI chr 6:33,112,516...33,129,113
Ensembl chr 6:33,112,451...33,129,084
JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 increases response to substance
increases expression
EXP HLA-DRB1 protein mutant form results in increased susceptibility to beryllium sulfate
beryllium sulfate results in increased expression of HLA-DRB1 mRNA
CTD PMID:16272364 PMID:16314022 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,578,769...32,589,848
JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 increases expression EXP beryllium sulfate results in increased expression of HNRNPA1 mRNA CTD PMID:16314022 NCBI chr12:54,280,726...54,287,087
Ensembl chr12:54,280,193...54,287,088
JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions
increases secretion
increases expression
EXP 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [beryllium sulfate results in increased expression of ICAM1 mRNA]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [beryllium sulfate results in increased secretion of ICAM1 protein]; Dimethyl Sulfoxide inhibits the reaction [beryllium sulfate results in increased secretion of ICAM1 protein]
beryllium sulfate results in increased expression of ICAM1 mRNA; beryllium sulfate results in increased expression of ICAM1 protein
CTD PMID:18539414 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IFNG interferon gamma increases expression
multiple interactions
EXP
ISO
beryllium sulfate results in increased expression of IFNG protein
[beryllium sulfate co-treated with IFNG protein] results in increased expression of CREB1 protein; [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUN protein; [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUNB protein; [beryllium sulfate co-treated with IFNG protein] results in increased expression of NFKB1 protein; beryllium sulfate promotes the reaction [IFNG protein results in increased expression of TNF protein]
CTD PMID:10755710 PMID:10755711 PMID:20974702 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IL18 interleukin 18 increases expression EXP beryllium sulfate results in increased expression of IL18 mRNA; beryllium sulfate results in increased expression of IL18 protein CTD PMID:16100009 NCBI chr11:112,143,251...112,164,104
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL2 interleukin 2 increases expression ISO beryllium sulfate results in increased expression of IL2 mRNA CTD PMID:9328138 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL5 interleukin 5 increases expression ISO beryllium sulfate results in increased expression of IL5 mRNA CTD PMID:9328138 NCBI chr 5:132,539,194...132,556,864
Ensembl chr 5:132,541,445...132,556,838
JBrowse link
G IL6 interleukin 6 increases expression ISO beryllium sulfate results in increased expression of IL6 mRNA CTD PMID:9328138 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G ITGB3 integrin subunit beta 3 increases expression EXP beryllium sulfate results in increased expression of ITGB3 mRNA CTD PMID:16314022 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA]; [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUN protein; Dactinomycin inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA]; Ro 31-8220 inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA] CTD PMID:10755711 PMID:11568973 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUNB protein CTD PMID:10755711 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor increases expression ISO beryllium sulfate results in increased expression of MYC protein CTD PMID:2009323 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G NEDD8 NEDD8 ubiquitin like modifier increases expression EXP beryllium sulfate results in increased expression of NEDD8 mRNA CTD PMID:16314022 NCBI chr14:24,216,857...24,232,367
Ensembl chr14:24,216,857...24,232,367
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions ISO [beryllium sulfate co-treated with IFNG protein] results in increased expression of NFKB1 protein CTD PMID:10755711 NCBI chr 4:102,501,266...102,617,302
Ensembl chr 4:102,501,331...102,617,302
JBrowse link
G NOVA1 NOVA alternative splicing regulator 1 increases expression EXP beryllium sulfate results in increased expression of NOVA1 mRNA CTD PMID:16314022 NCBI chr14:26,443,090...26,598,033
Ensembl chr14:26,443,090...26,598,033
JBrowse link
G RHOA ras homolog family member A increases expression EXP beryllium sulfate results in increased expression of RHOA mRNA CTD PMID:16314022 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998
JBrowse link
G RPL22 ribosomal protein L22 increases expression EXP beryllium sulfate results in increased expression of RPL22 mRNA CTD PMID:16314022 NCBI chr 1:6,185,020...6,199,595
Ensembl chr 1:6,185,020...6,209,389
JBrowse link
G RPL30 ribosomal protein L30 increases expression EXP beryllium sulfate results in increased expression of RPL30 mRNA CTD PMID:16314022 NCBI chr 8:98,041,721...98,045,545
Ensembl chr 8:98,024,851...98,046,469
JBrowse link
G RPL37A ribosomal protein L37a increases expression EXP beryllium sulfate results in increased expression of RPL37A mRNA CTD PMID:16314022 NCBI chr 2:216,498,844...216,504,086
Ensembl chr 2:216,498,825...216,579,180
JBrowse link
G RPS7 ribosomal protein S7 increases expression EXP beryllium sulfate results in increased expression of RPS7 mRNA CTD PMID:16314022 NCBI chr 2:3,575,260...3,580,920
Ensembl chr 2:3,575,260...3,580,920
JBrowse link
G RUNX1 RUNX family transcription factor 1 multiple interactions EXP beryllium sulfate promotes the reaction [RUNX1 protein binds to CCL3 promoter] CTD PMID:16314022 NCBI chr21:34,787,801...35,049,334
Ensembl chr21:34,787,801...36,004,667
JBrowse link
G SERPINB2 serpin family B member 2 increases expression EXP beryllium sulfate results in increased expression of SERPINB2 mRNA CTD PMID:16314022 NCBI chr18:63,887,705...63,903,890
Ensembl chr18:63,871,692...63,903,888
JBrowse link
G SFTPD surfactant protein D increases expression EXP beryllium sulfate results in increased expression of SFTPD mRNA CTD PMID:16314022 NCBI chr10:79,937,740...79,982,236
Ensembl chr10:79,937,467...79,982,614
JBrowse link
G TAT tyrosine aminotransferase multiple interactions ISO beryllium sulfate inhibits the reaction [Hydrocortisone results in increased expression of TAT protein] CTD PMID:6120038 NCBI chr16:71,565,660...71,577,092
Ensembl chr16:71,565,660...71,577,092
JBrowse link
G TMSB4X thymosin beta 4 X-linked increases expression EXP beryllium sulfate results in increased expression of TMSB4X mRNA CTD PMID:16314022 NCBI chr  X:12,975,110...12,977,223
Ensembl chr  X:12,975,110...12,977,227
JBrowse link
G TNF tumor necrosis factor increases expression
multiple interactions
ISO beryllium sulfate results in increased expression of TNF mRNA; beryllium sulfate results in increased expression of TNF protein
beryllium sulfate promotes the reaction [IFNG protein results in increased expression of TNF protein]
CTD PMID:10755710 PMID:10755711 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TP53 tumor protein p53 multiple interactions
increases expression
EXP beryllium sulfate promotes the reaction [TP53 protein binds to CDKN1A promoter]
beryllium sulfate results in increased expression of TP53 protein
CTD PMID:17395767 PMID:20974702 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G WNT4 Wnt family member 4 increases expression EXP beryllium sulfate results in increased expression of WNT4 mRNA CTD PMID:16314022 NCBI chr 1:22,117,308...22,143,981
Ensembl chr 1:22,117,313...22,143,969
JBrowse link
G ZNF77 zinc finger protein 77 increases expression EXP beryllium sulfate results in increased expression of ZNF77 mRNA CTD PMID:16314022 NCBI chr19:2,933,218...2,944,971
Ensembl chr19:2,933,218...2,944,971
JBrowse link
beryllium(0) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN2A cyclin dependent kinase inhibitor 2A multiple interactions ISO [Beryllium results in increased methylation of CDKN2A promoter] which results in decreased expression of CDKN2A mRNA CTD PMID:11872642 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
JBrowse link
G ESR1 estrogen receptor 1 increases methylation ISO Beryllium results in increased methylation of ESR1 gene CTD PMID:11872642 NCBI chr 6:151,654,148...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 affects binding
increases response to substance
EXP HLA-DPB1 protein mutant form binds to Beryllium
HLA-DPB1 gene polymorphism results in increased susceptibility to Beryllium; HLA-DPB1 gene SNP results in increased susceptibility to Beryllium; HLA-DPB1 protein mutant form results in increased susceptibility to Beryllium
CTD PMID:11551429 PMID:15273960 PMID:17956852 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,990...33,089,696
JBrowse link
G HRAS HRas proto-oncogene, GTPase increases mutagenesis ISO Beryllium results in increased mutagenesis of HRAS gene CTD PMID:7545909 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321
JBrowse link
G IL1B interleukin 1 beta increases expression
affects expression
EXP Beryllium results in increased expression of IL1B mRNA
Beryllium affects the expression of IL1B mRNA
CTD PMID:8473757 PMID:8629860 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G TNF tumor necrosis factor increases response to substance
increases secretion
increases expression
EXP TNF promoter polymorphism results in increased susceptibility to Beryllium
Beryllium results in increased secretion of TNF protein
Beryllium results in increased expression of TNF mRNA
CTD PMID:8629860 PMID:12449171 PMID:15127972 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
calcium atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions EXP Calcium deficiency inhibits the reaction [ABCB1 protein results in increased export of Xanthenes]; Calcium inhibits the reaction [Magnesium results in increased activity of ABCB1 protein] CTD PMID:2900677 PMID:25862123 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCB11 ATP binding cassette subfamily B member 11 multiple interactions EXP Calcium deficiency inhibits the reaction [ABCB11 protein results in increased export of Taurocholic Acid] CTD PMID:25862123 NCBI chr 2:168,915,468...169,031,396
Ensembl chr 2:168,915,498...169,031,324
JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 multiple interactions EXP Calcium deficiency inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein] CTD PMID:25862123 NCBI chr10:99,782,602...99,853,741
Ensembl chr10:99,782,640...99,852,594
JBrowse link
G ACO2 aconitase 2 increases activity
multiple interactions
ISO Calcium results in increased activity of ACO2 protein
[Calcium results in increased activity of ACO2 protein] which results in increased reduction of thiazolyl blue; [Nicardipine results in decreased uptake of Calcium] which results in decreased activity of ACO2 protein
CTD PMID:12548706 NCBI chr22:41,468,756...41,528,979
Ensembl chr22:41,447,830...41,529,273
JBrowse link
G ACTB actin beta multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of ACTB mRNA CTD PMID:15913539 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902
JBrowse link
G ADCY5 adenylate cyclase 5 decreases activity
increases response to substance
EXP
ISO
Calcium results in decreased activity of ADCY5 protein
ADCY5 protein results in increased susceptibility to Calcium
CTD PMID:12065575 PMID:12869393 NCBI chr 3:123,282,296...123,449,090
Ensembl chr 3:123,282,296...123,449,090
JBrowse link
G ADCY9 adenylate cyclase 9 multiple interactions EXP Calcium inhibits the reaction [Miconazole results in increased activity of ADCY9 protein]; Tacrolimus inhibits the reaction [Calcium inhibits the reaction [Miconazole results in increased activity of ADCY9 protein]] CTD PMID:30607468 NCBI chr16:3,953,387...4,116,442
Ensembl chr16:3,953,387...4,116,442
JBrowse link
G ADCYAP1 adenylate cyclase activating polypeptide 1 increases abundance
affects abundance
multiple interactions
ISO ADCYAP1 protein results in increased abundance of Calcium
ADCYAP1 protein affects the abundance of Calcium
Calcium affects the reaction [ADCYAP1 protein results in increased expression of SELENOT mRNA]; SELENOT protein affects the reaction [ADCYAP1 protein results in increased abundance of Calcium]
CTD PMID:18198219 PMID:21039959 NCBI chr18:904,384...912,172
Ensembl chr18:904,871...912,172
JBrowse link
G ADGRL1 adhesion G protein-coupled receptor L1 multiple interactions ISO [alpha-latrotoxin binds to ADGRL1 protein] which results in increased uptake of Calcium; [black widow spider venom binds to ADGRL1 protein] which results in increased uptake of Calcium CTD PMID:10026162 NCBI chr19:14,147,737...14,206,245
Ensembl chr19:14,147,743...14,206,187
JBrowse link
G ADGRL2 adhesion G protein-coupled receptor L2 multiple interactions ISO [alpha-latrotoxin binds to ADGRL2 protein] which results in increased uptake of Calcium; [black widow spider venom binds to ADGRL2 protein] which results in increased uptake of Calcium CTD PMID:10026162 NCBI chr 1:81,306,104...81,993,932
Ensembl chr 1:81,306,147...81,992,436
JBrowse link
G ADM adrenomedullin decreases expression EXP Calcium results in decreased expression of ADM mRNA CTD PMID:20682585 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397
JBrowse link
G ADRA1A adrenoceptor alpha 1A multiple interactions
affects transport
ISO
EXP
[Epinephrine binds to and results in increased activity of ADRA1A protein] which results in increased transport of Calcium; [Phenylephrine binds to and results in increased activity of ADRA1A protein] which results in increased transport of Calcium; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of EIF4EBP1 protein]; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of MTOR protein]; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of RPS6KB1 protein]
5-methylurapidil inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; [A 61603 results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Epinephrine binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Oxymetazoline binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]
ADRA1A protein affects the transport of Calcium
CTD PMID:12935885 PMID:15306222 PMID:15639650 PMID:15672411 PMID:16498073 More... NCBI chr 8:26,738,113...26,870,994
Ensembl chr 8:26,748,150...26,867,278
JBrowse link
G ADRA1B adrenoceptor alpha 1B multiple interactions EXP [Epinephrine binds to and results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; [Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; Carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; Carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium] CTD PMID:15306222 PMID:16498073 PMID:20030735 NCBI chr 5:159,916,482...159,989,205
Ensembl chr 5:159,865,080...159,973,012
JBrowse link
G ADRA1D adrenoceptor alpha 1D multiple interactions EXP [Epinephrine binds to and results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; [Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium] CTD PMID:15306222 PMID:20030735 NCBI chr20:4,220,630...4,249,287
Ensembl chr20:4,220,630...4,249,287
JBrowse link
G ADRA2A adrenoceptor alpha 2A multiple interactions EXP [Epinephrine binds to and results in increased activity of ADRA2A protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA2A protein] which results in increased abundance of Calcium CTD PMID:20030735 NCBI chr10:111,077,029...111,080,907
Ensembl chr10:111,077,029...111,080,907
JBrowse link
G ADRA2B adrenoceptor alpha 2B multiple interactions EXP [Epinephrine binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; [Oxymetazoline binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; [xylometazoline binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium CTD PMID:20030735 NCBI chr 2:96,112,876...96,116,571
Ensembl chr 2:96,112,876...96,116,571
JBrowse link
G ADRA2C adrenoceptor alpha 2C multiple interactions EXP [Epinephrine binds to and results in increased activity of ADRA2C protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA2C protein] which results in increased abundance of Calcium CTD PMID:20030735 NCBI chr 4:3,766,385...3,768,526
Ensembl chr 4:3,766,348...3,768,526
JBrowse link
G ADRB2 adrenoceptor beta 2 multiple interactions ISO
EXP
[Terbutaline binds to and results in increased activity of ADRB2 protein] which affects the abundance of Calcium
[Benzo(a)pyrene binds to ADRB2 protein] which results in increased transport of Calcium; ADRB2 protein promotes the reaction [Benzo(a)pyrene results in increased transport of Calcium]
CTD PMID:10372813 PMID:22167199 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623
JBrowse link
G AGO2 argonaute RISC catalytic component 2 multiple interactions ISO Calcium affects the reaction [PICK1 protein binds to AGO2 protein]; Calcium deficiency inhibits the reaction [Excitatory Amino Acid Agonists inhibits the reaction [PICK1 protein binds to AGO2 protein]] CTD PMID:28404816 NCBI chr 8:140,520,156...140,642,406
Ensembl chr 8:140,520,156...140,635,633
JBrowse link
G AGT angiotensinogen increases uptake
affects localization
multiple interactions
increases abundance
EXP
ISO
AGT protein results in increased uptake of Calcium
AGT protein affects the localization of Calcium
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [AGT protein affects the localization of Calcium]; bafilomycin A1 inhibits the reaction [AGT protein affects the localization of Calcium]; Heparin inhibits the reaction [AGT protein affects the localization of Calcium]; Losartan inhibits the reaction [AGT protein affects the localization of Calcium]; Saralasin inhibits the reaction [AGT protein affects the localization of Calcium]; Sirolimus inhibits the reaction [AGT protein affects the localization of Calcium]; xestospongin C inhibits the reaction [AGT protein affects the localization of Calcium]
[AGT protein results in increased abundance of Calcium] which results in increased abundance of Reactive Oxygen Species
Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]
benidipine inhibits the reaction [AGT protein results in increased uptake of Calcium]; Mibefradil inhibits the reaction [AGT protein results in increased uptake of Calcium]
CTD PMID:10660688 PMID:18331727 PMID:18854758 PMID:21613610 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
JBrowse link
G AGTR1 angiotensin II receptor type 1 affects expression ISO Calcium affects the expression of AGTR1A mRNA CTD PMID:15913539 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008
JBrowse link
G AKAP1 A-kinase anchoring protein 1 affects expression ISO Calcium affects the expression of AKAP1 mRNA CTD PMID:15913539 NCBI chr17:57,085,246...57,121,344
Ensembl chr17:57,085,092...57,121,346
JBrowse link
G AKAP11 A-kinase anchoring protein 11 affects expression ISO Calcium affects the expression of AKAP11 mRNA CTD PMID:15913539 NCBI chr13:42,271,470...42,323,266
Ensembl chr13:42,272,152...42,323,261
JBrowse link
G AKT1 AKT serine/threonine kinase 1 affects abundance
affects expression
multiple interactions
affects response to substance
EXP
ISO
AKT1 protein affects the abundance of Calcium
Calcium affects the expression of AKT1 mRNA
[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein; Calcium affects the reaction [P2RY1 protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; CAMKK2 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; PDK1 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; PX-866 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; STO 609 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; W 7 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]
AKT1 protein affects the susceptibility to Calcium
CTD PMID:15913539 PMID:16094411 PMID:16236484 PMID:28634229 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member multiple interactions ISO
EXP
ALDH2 protein inhibits the reaction [Ethanol affects the abundance of Calcium]
Calcium affects the reaction [ALDH2 gene SNP affects the abundance of Lead]
CTD PMID:17590987 PMID:28212632 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
JBrowse link
G ALG2 ALG2 alpha-1,3/1,6-mannosyltransferase affects binding EXP Calcium binds to ALG2 protein CTD PMID:18997320 NCBI chr 9:99,216,425...99,221,942
Ensembl chr 9:99,216,425...99,221,942
JBrowse link
G ALOX5 arachidonate 5-lipoxygenase multiple interactions EXP Calcium promotes the reaction [L 708714 binds to ALOX5 protein] CTD PMID:7577949 NCBI chr10:45,374,209...45,446,121
Ensembl chr10:45,374,176...45,446,119
JBrowse link
G ALPP alkaline phosphatase, placental affects binding EXP Calcium binds to ALPP protein CTD PMID:16815919 NCBI chr 2:232,378,751...232,382,889
Ensembl chr 2:232,378,724...232,382,889
JBrowse link
G ANXA1 annexin A1 affects activity ISO Calcium affects the activity of ANXA1 protein CTD PMID:20655937 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393
JBrowse link
G ANXA5 annexin A5 multiple interactions EXP Calcium binds to and results in increased activity of ANXA5 protein; Calcium promotes the reaction [Phosphatidylserines binds to ANXA5 protein] CTD PMID:11578147 PMID:16076491 NCBI chr 4:121,667,946...121,696,994
Ensembl chr 4:121,667,946...121,696,995
JBrowse link
G AOC1 amine oxidase copper containing 1 affects binding EXP AOC1 protein binds to Calcium CTD PMID:12072962 NCBI chr 7:150,824,875...150,861,504
Ensembl chr 7:150,824,627...150,861,504
JBrowse link
G APOE apolipoprotein E affects abundance
affects expression
ISO APOE protein affects the abundance of Calcium
Calcium affects the expression of APOE mRNA
CTD PMID:15913539 PMID:17899169 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G APOM apolipoprotein M affects expression ISO Calcium affects the expression of APOM mRNA CTD PMID:15913539 NCBI chr 6:31,652,404...31,658,210
Ensembl chr 6:31,652,416...31,658,210
JBrowse link
G APP amyloid beta precursor protein multiple interactions
increases uptake
affects abundance
ISO 2,4-Dinitrophenol affects the reaction [APP protein affects the abundance of Calcium]; 3-nitrophenol affects the reaction [APP protein affects the abundance of Calcium]; 4-anisidine affects the reaction [APP protein affects the abundance of Calcium]
APP protein modified form results in increased uptake of Calcium; APP protein results in increased uptake of Calcium
Calcium deficiency inhibits the reaction [APP protein modified form results in increased uptake of Calcium]; EDN3 protein inhibits the reaction [APP protein results in increased uptake of Calcium]; Flurbiprofen inhibits the reaction [APP protein results in increased uptake of Calcium]; Ibuprofen inhibits the reaction [APP protein results in increased uptake of Calcium]; Indomethacin inhibits the reaction [APP protein results in increased uptake of Calcium]; Nimodipine inhibits the reaction [APP protein results in increased uptake of Calcium]; Ruthenium Red inhibits the reaction [APP protein modified form results in increased uptake of Calcium]; Salicylates inhibits the reaction [APP protein results in increased uptake of Calcium]; sulindac sulfide inhibits the reaction [APP protein results in increased uptake of Calcium]
CTD PMID:12383957 PMID:18648507 PMID:18949129 PMID:24457011 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,550...26,171,128
JBrowse link
G ARRB2 arrestin beta 2 multiple interactions ISO ARRB2 protein affects the abundance of and affects the localization of Calcium
ARRB2 promotes the reaction [carvedilol results in increased uptake of Calcium]
CTD PMID:16210646 PMID:21078978 NCBI chr17:4,710,619...4,721,500
Ensembl chr17:4,710,596...4,721,499
JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of ATP1A1 mRNA CTD PMID:15913539 NCBI chr 1:116,372,986...116,410,259
Ensembl chr 1:116,372,668...116,410,261
JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 multiple interactions ISO Calcium affects the reaction [Ouabain results in increased expression of ATP1B1 mRNA] CTD PMID:11204457 NCBI chr 1:169,106,690...169,132,719
Ensembl chr 1:169,105,697...169,132,722
JBrowse link
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 affects transport
multiple interactions
ISO ATP2A1 protein affects the transport of Calcium
[Phenols results in decreased activity of ATP2A1 protein] which results in decreased transport of Calcium
CTD PMID:11230109 PMID:18773882 NCBI chr16:28,878,488...28,904,466
Ensembl chr16:28,878,405...28,904,466
JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 affects abundance
affects transport
multiple interactions
affects uptake
affects export
ISO ATP2A2 protein affects the abundance of Calcium
ATP2A2 protein affects the transport of Calcium
[[Phenylephrine results in increased activity of SLC9A1 protein] which results in increased transport of Calcium] which results in increased expression of ATP2A2 protein; [Phenylephrine results in decreased expression of ATP2A2 protein] which results in decreased transport of Calcium; [Thapsigargin results in decreased activity of ATP2A2 protein] which results in decreased transport of Calcium
PPP3R1 gene mutant form inhibits the reaction [ATP2A2 protein affects the transport of Calcium]
ATP2A2 protein alternative form affects the uptake of Calcium
ATP2A2 protein alternative form affects the export of Calcium
CTD PMID:11679415 PMID:16236312 PMID:17287366 PMID:19244478 PMID:19328205 More... NCBI chr12:110,281,247...110,351,093
Ensembl chr12:110,280,756...110,351,093
JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 multiple interactions
increases export
EXP caloxin 1b1 inhibits the reaction [ATP2B1 protein results in increased export of Calcium] CTD PMID:16452157 NCBI chr12:89,588,049...89,709,366
Ensembl chr12:89,588,049...89,709,300
JBrowse link
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 increases export
multiple interactions
EXP ATP2B4 protein results in increased export of Calcium
caloxin 1b1 inhibits the reaction [ATP2B4 protein results in increased export of Calcium]
CTD PMID:16452157 NCBI chr 1:203,626,832...203,744,081
Ensembl chr 1:203,626,787...203,744,081
JBrowse link
G ATP8B1 ATPase phospholipid transporting 8B1 multiple interactions ISO Calcium inhibits the reaction [ATP8B1 protein results in increased transport of Phosphatidylserines] CTD PMID:11584374 NCBI chr18:57,646,426...57,803,822
Ensembl chr18:57,646,426...57,803,315
JBrowse link
G AVP arginine vasopressin multiple interactions
increases uptake
increases abundance
ISO 1-Butanol inhibits the reaction [AVP protein results in increased abundance of Calcium]; 2-(4-amylcinnamoyl)amino-4-chlorobenzoic acid inhibits the reaction [AVP protein results in increased abundance of Calcium]; [[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; [[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein; [AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium; [AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium; AVP protein results in increased import of and results in increased abundance of Calcium; Carvedilol inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium]; Chromium affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; Chromium affects the reaction [INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; chromium tripicolinate affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; chromium tripicolinate affects the reaction [INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; INS1 protein affects the reaction [Chromium affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; INS1 protein affects the reaction [chromium tripicolinate affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; Nicardipine inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium]; Nifedipine inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium] CTD PMID:9446840 PMID:11356622 PMID:11553362 PMID:14711191 PMID:21039959 NCBI chr20:3,082,556...3,093,521
Ensembl chr20:3,082,556...3,084,724
JBrowse link
G AVPR1A arginine vasopressin receptor 1A multiple interactions ISO [[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; [[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein; [AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium; [NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium; Carbachol promotes the reaction [[NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium]; Nicardipine inhibits the reaction [[NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium]; Nicardipine inhibits the reaction [Carbachol promotes the reaction [[NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium]] CTD PMID:11553362 PMID:12646291 NCBI chr12:63,142,759...63,151,201
Ensembl chr12:63,142,759...63,151,201
JBrowse link
G AVPR2 arginine vasopressin receptor 2 affects expression ISO Calcium affects the expression of AVPR2 mRNA CTD PMID:15913539 NCBI chr  X:153,902,625...153,907,166
Ensembl chr  X:153,902,531...153,907,166
JBrowse link
G AXIN1 axin 1 affects expression ISO Calcium affects the expression of AXIN1 mRNA CTD PMID:15913539 NCBI chr16:287,440...355,226
Ensembl chr16:287,440...352,723
JBrowse link
G BAD BCL2 associated agonist of cell death affects expression ISO Calcium affects the expression of BAD mRNA CTD PMID:15913539 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
JBrowse link
G BDKRB1 bradykinin receptor B1 multiple interactions EXP
ISO
2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [[kallidin, des-Arg(10)- results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]; [kallidin, des-Arg(10)- results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium; Sodium affects the reaction [[kallidin, des-Arg(10)- results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]
[kallidin, des-Arg(10)- binds to and results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium; bradykinin, Lys-Leu(8)-desArg(9)- inhibits the reaction [[kallidin, des-Arg(10)- binds to and results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]; Indomethacin inhibits the reaction [[kallidin, des-Arg(10)- binds to and results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]
CTD PMID:15703175 PMID:22554775 NCBI chr14:96,256,210...96,264,763
Ensembl chr14:96,256,210...96,268,967
JBrowse link
G BDKRB2 bradykinin receptor B2 multiple interactions EXP
ISO
BDKRB2 protein affects the reaction [KNG1 protein affects the abundance of Calcium]
BDKRB2 protein affects the reaction [pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]]
CTD PMID:16473424 PMID:18054572 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166
JBrowse link
G BDNF brain derived neurotrophic factor multiple interactions
increases transport
ISO
EXP
[Cadmium results in decreased transport of Calcium] inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein]; Calcium affects the reaction [Oxygen deficiency results in increased secretion of BDNF protein]
BDNF protein results in increased transport of Calcium
3,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]; 3,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide promotes the reaction [Tetrodotoxin inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]]; Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]; Tetrodotoxin inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]
CTD PMID:16553631 PMID:26095976 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G BEST1 bestrophin 1 increases activity
multiple interactions
ISO Calcium results in increased activity of BEST1 protein
[PAR-1-activating peptide results in increased abundance of Calcium] which results in increased activity of BEST1 protein
CTD PMID:19828819 NCBI chr11:61,946,722...61,965,515
Ensembl chr11:61,950,063...61,965,515
JBrowse link
G BMP4 bone morphogenetic protein 4 affects expression
multiple interactions
ISO
EXP
Calcium affects the expression of BMP4 mRNA
[Calcium binds to MGP protein] which binds to and results in decreased activity of BMP4 protein; [Edetic Acid inhibits the reaction [Calcium binds to MGP protein]] inhibits the reaction [MGP protein binds to BMP4 protein]
CTD PMID:15913539 PMID:18369157 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link
G BTK Bruton tyrosine kinase affects transport ISO BTK protein affects the transport of Calcium CTD PMID:12848851 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,447...101,390,796
JBrowse link
G C5 complement C5 multiple interactions EXP
ISO
[C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium; resveratrol inhibits the reaction [[C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium] CTD PMID:19284563 PMID:19346296 NCBI chr 9:120,952,335...121,074,865
Ensembl chr 9:120,952,335...121,050,275
JBrowse link
G CA4 carbonic anhydrase 4 affects expression ISO Calcium affects the expression of CA4 mRNA CTD PMID:15913539 NCBI chr17:60,149,942...60,179,021
Ensembl chr17:60,149,942...60,170,899
JBrowse link
G CACNA1A calcium voltage-gated channel subunit alpha1 A increases transport
multiple interactions
ISO CACNA1A protein results in increased transport of Calcium
Allethrins inhibits the reaction [CACNA1A protein results in increased transport of Calcium]
CTD PMID:14634047 NCBI chr19:13,206,442...13,506,479
Ensembl chr19:13,206,442...13,633,025
JBrowse link
G CACNA1B calcium voltage-gated channel subunit alpha1 B multiple interactions
decreases uptake
increases transport
ISO decamethrin inhibits the reaction [CACNA1B protein results in increased transport of Calcium]; decamethrin promotes the reaction [CACNA1B gene mutant form results in increased transport of Calcium]
CACNA1B protein alternative form results in decreased uptake of Calcium
CTD PMID:18383452 PMID:22891239 NCBI chr 9:137,877,782...138,124,619
Ensembl chr 9:137,877,782...138,124,624
JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C increases transport
multiple interactions
EXP
ISO
CACNA1C protein results in increased transport of Calcium
[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium; [CACNA2D4 protein binds to CACNA1C protein binds to CACNB3 protein] which results in increased transport of Calcium; CACNA2D4 protein promotes the reaction [[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium]
Allethrins inhibits the reaction [CACNA1C protein results in increased transport of Calcium]
CTD PMID:12181424 PMID:14634047 PMID:15299022 NCBI chr12:1,969,552...2,697,950
Ensembl chr12:1,970,772...2,697,950
JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D affects transport
multiple interactions
ISO CACNA1D protein affects the transport of Calcium
CACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Calcium]
[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium; [CACNA1D protein results in increased uptake of Calcium] which affects the localization of SLC2A2 protein; [CACNA1D protein results in increased uptake of Calcium] which results in increased phosphorylation of MYL9 protein; CACNA2D1 protein promotes the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]; gabapentin affects the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]; SLC5A1 protein affects the reaction [CACNA1D protein results in increased uptake of Calcium]
CTD PMID:15357422 PMID:17272349 PMID:19796812 PMID:27798183 NCBI chr 3:53,494,611...53,813,733
Ensembl chr 3:53,328,963...53,813,733
JBrowse link
G CACNA1E calcium voltage-gated channel subunit alpha1 E increases transport
multiple interactions
EXP
ISO
CACNA1E protein results in increased transport of Calcium
Calcium inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]
Cadmium inhibits the reaction [CACNA1E protein results in increased transport of Calcium]; Nickel inhibits the reaction [CACNA1E protein results in increased transport of Calcium]
CTD PMID:10627594 PMID:10669483 PMID:12663092 NCBI chr 1:181,317,712...181,808,084
Ensembl chr 1:181,317,690...181,808,084
JBrowse link
G CACNA1F calcium voltage-gated channel subunit alpha1 F increases transport ISO CACNA1F protein results in increased transport of Calcium CTD PMID:14744918 NCBI chr  X:49,205,063...49,233,404
Ensembl chr  X:49,205,063...49,233,371
JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G increases transport
multiple interactions
ISO CACNA1G protein results in increased transport of Calcium
Allethrins inhibits the reaction [CACNA1G protein results in increased transport of Calcium]
CACNG2 protein affects the reaction [CACNA1G protein results in increased transport of Calcium]; CACNG4 protein affects the reaction [CACNA1G protein results in increased transport of Calcium]; CACNG5 protein affects the reaction [CACNA1G protein results in increased transport of Calcium]
CTD PMID:10734232 PMID:11073957 PMID:14634047 NCBI chr17:50,560,715...50,629,625
Ensembl chr17:50,560,715...50,627,474
JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H increases transport
multiple interactions
EXP
ISO
CACNA1H protein results in increased transport of Calcium
Amiloride inhibits the reaction [CACNA1H protein results in increased transport of Calcium]; Nickel inhibits the reaction [CACNA1H protein results in increased transport of Calcium]
Amiloride inhibits the reaction [CACNA1H protein results in increased transport of Calcium]; Mibefradil inhibits the reaction [CACNA1H protein results in increased transport of Calcium]; Nickel inhibits the reaction [CACNA1H protein results in increased transport of Calcium]
CTD PMID:9930755 PMID:11073957 PMID:11897840 NCBI chr16:1,153,106...1,221,769
Ensembl chr16:1,153,106...1,221,771
JBrowse link
G CACNA1I calcium voltage-gated channel subunit alpha1 I increases transport ISO CACNA1I protein results in increased transport of Calcium CTD PMID:11073957 NCBI chr22:39,570,753...39,689,737
Ensembl chr22:39,570,753...39,689,735
JBrowse link
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 multiple interactions
increases transport
ISO [gabapentin results in decreased activity of CACNA2D1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]; CACNA2D1 protein affects the reaction [Potassium Chloride results in increased transport of Calcium]
CACNA2D1 protein promotes the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]
CACNA2D1 protein results in increased transport of Calcium
CTD PMID:15474003 PMID:17442347 PMID:17881535 PMID:19796812 NCBI chr 7:81,946,444...82,443,956
Ensembl chr 7:81,946,444...82,443,777
JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 affects transport
multiple interactions
ISO CACNA2D2 protein affects the transport of Calcium
CACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Calcium]
CTD PMID:14660671 PMID:27798183 NCBI chr 3:50,362,613...50,504,244
Ensembl chr 3:50,362,613...50,504,244
JBrowse link
G CACNA2D4 calcium voltage-gated channel auxiliary subunit alpha2delta 4 multiple interactions EXP [CACNA2D4 protein binds to CACNA1C protein binds to CACNB3 protein] which results in increased transport of Calcium; CACNA2D4 protein promotes the reaction [[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium] CTD PMID:12181424 NCBI chr12:1,791,963...1,922,606
Ensembl chr12:1,791,963...1,918,666
JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 multiple interactions EXP
ISO
[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium; [CACNA2D4 protein binds to CACNA1C protein binds to CACNB3 protein] which results in increased transport of Calcium; CACNA2D4 protein promotes the reaction [[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium]
[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium; CACNA2D1 protein promotes the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]; gabapentin affects the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]
CTD PMID:12181424 PMID:19796812 NCBI chr12:48,814,432...48,828,941
Ensembl chr12:48,813,794...48,828,941
JBrowse link
G CACNG2 calcium voltage-gated channel auxiliary subunit gamma 2 multiple interactions ISO CACNG2 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] CTD PMID:10734232 NCBI chr22:36,560,857...36,703,752
Ensembl chr22:36,560,857...36,703,752
JBrowse link
G CACNG4 calcium voltage-gated channel auxiliary subunit gamma 4 multiple interactions ISO CACNG4 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] CTD PMID:10734232 NCBI chr17:66,964,707...67,033,398
Ensembl chr17:66,964,707...67,033,398
JBrowse link
G CACNG5 calcium voltage-gated channel auxiliary subunit gamma 5 multiple interactions ISO CACNG5 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] CTD PMID:10734232 NCBI chr17:66,835,117...66,894,751
Ensembl chr17:66,835,117...66,894,751
JBrowse link
G CALB1 calbindin 1 affects expression ISO Calcium affects the expression of CALB1 mRNA CTD PMID:15913539 NCBI chr 8:90,058,608...90,082,879
Ensembl chr 8:90,058,608...90,095,475
JBrowse link
G CALCA calcitonin related polypeptide alpha multiple interactions
increases expression
ISO
EXP
rimabotulinumtoxinB inhibits the reaction [[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein]; rimabotulinumtoxinB inhibits the reaction [[Potassium co-treated with Calcium] results in increased secretion of CALCA protein]
Calcium promotes the reaction [Lipopolysaccharides results in increased expression of CALCA mRNA]
Calcium results in increased expression of CALCA mRNA
Calcium results in increased expression of CALCA protein
[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein; [KNG1 protein alternative form co-treated with Calcium] results in increased secretion of CALCA protein; [Potassium co-treated with Calcium] results in increased secretion of CALCA protein; [Sumatriptan results in increased abundance of Calcium] inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA]; botulinum toxin type D inhibits the reaction [[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein]; botulinum toxin type D inhibits the reaction [[Potassium co-treated with Calcium] results in increased secretion of CALCA protein]; Botulinum Toxins, Type A inhibits the reaction [[Potassium co-treated with Calcium] results in increased secretion of CALCA protein]; Calcium affects the reaction [Capsaicin inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Calcium affects the reaction [Capsaicin inhibits the reaction [mustard oil results in increased secretion of CALCA protein]]; Calcium affects the reaction [mustard oil inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Calcium deficiency inhibits the reaction [safranal results in increased secretion of CALCA protein]; Calcium inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA]
CTD PMID:2470235 PMID:12574409 PMID:17590514 PMID:17666428 PMID:20682585 More... NCBI chr11:14,966,668...14,972,361
Ensembl chr11:14,966,668...14,972,351
JBrowse link
G CALM1 calmodulin 1 multiple interactions
affects binding
EXP
ISO
Calcium affects the folding of [CALM1 protein binds to RYR1 protein modified form]; Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]
Calcium binds to CALM1 protein
[Calcium binds to CALM1 protein] promotes the reaction [NOS1 protein results in increased chemical synthesis of Nitric Oxide]; [Calcium binds to CALM1 protein] which binds to and affects the folding of and results in increased activity of NOS1 protein; Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]; Calcium affects the reaction [CALM1 protein modified form binds to and affects the activity of RYR1 protein]; Calcium binds to and affects the folding of CALM1 protein
CTD PMID:15381065 PMID:15628869 PMID:17098364 NCBI chr14:90,396,502...90,408,268
Ensembl chr14:90,396,502...90,408,268
JBrowse link
G CALR calreticulin affects response to substance
multiple interactions
ISO CALR protein affects the susceptibility to Calcium
CALR protein promotes the reaction [KNG1 protein modified form results in increased abundance of Calcium]
CTD PMID:7961812 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489
JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta affects expression ISO Calcium affects the expression of CAMK2D mRNA CTD PMID:15913539 NCBI chr 4:113,451,032...113,762,177
Ensembl chr 4:113,418,054...113,761,927
JBrowse link
G CAMKK2 calcium/calmodulin dependent protein kinase kinase 2 multiple interactions EXP CAMKK2 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein] CTD PMID:28634229 NCBI chr12:121,237,692...121,297,819
Ensembl chr12:121,237,675...121,298,308
JBrowse link
G CAPN1 calpain 1 multiple interactions
increases cleavage
increases activity
EXP
ISO
[Caffeine co-treated with Alprazolam] promotes the reaction [Calcium results in increased activity of CAPN1 protein]; [Calcium co-treated with CAPN1 protein] results in increased degradation of TP73 protein modified form; [sodium arsenite results in increased abundance of Arsenic] promotes the reaction [[Calcium results in increased cleavage of CAPN1 protein] which results in increased degradation of CAPN1 protein]
calpain inhibitor III inhibits the reaction [Calcium results in increased activity of CAPN1 protein]
CTD PMID:19490937 PMID:21516125 PMID:21985864 PMID:31398423 NCBI chr11:65,181,373...65,212,006
Ensembl chr11:65,180,566...65,212,006
JBrowse link
G CASP3 caspase 3 multiple interactions ISO
EXP
[Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in increased expression of CASP3 mRNA]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in increased expression of CASP3 mRNA]; Calcium affects the reaction [sodium arsenite results in increased expression of CASP3 mRNA]
Calcium deficiency inhibits the reaction [Dasatinib results in increased activity of CASP3 protein]; Calcium deficiency inhibits the reaction [Ionomycin results in increased activity of CASP3 protein]
CTD PMID:24184500 PMID:29803841 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP9 caspase 9 multiple interactions ISO [Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in increased expression of CASP9 mRNA]]; Calcium affects the reaction [sodium arsenite results in increased expression of CASP9 mRNA] CTD PMID:24184500 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CASR calcium sensing receptor increases phosphorylation
multiple interactions
increases uptake
increases activity
affects expression
decreases response to substance
increases response to substance
EXP
ISO
Calcium results in increased phosphorylation of CASR protein
[Aluminum binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Calcium binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Calcium binds to and results in increased activity of CASR protein] which results in increased abundance of Inositol Phosphates; [Gadolinium binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Magnesium binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Neomycin binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; Calcium binds to and results in increased activity of CASR protein; Gadolinium inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]
CASR protein results in increased uptake of Calcium
Calcium results in increased activity of CASR protein
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [CASR protein results in increased uptake of Calcium]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [CASR protein results in increased uptake of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]; 2-aminoethoxydiphenyl borate inhibits the reaction [CASR protein results in increased uptake of Calcium]; [2-quinoxaline-carboxamide-N-adamantan-1-yl binds to and results in decreased activity of CASR protein] inhibits the reaction [Nickel results in increased abundance of Calcium]; [Calcium binds to and results in increased activity of CASR protein] which results in increased uptake of Calcium; [CASR protein mutant form results in increased susceptibility to Calcium] which results in increased abundance of Inositol 1,4,5-Trisphosphate; [Spermine binds to and results in increased activity of CASR protein] which results in increased uptake of Calcium; bisindolylmaleimide I inhibits the reaction [NPS R-467 promotes the reaction [Calcium results in increased phosphorylation of CASR protein]]; Calcium Chloride promotes the reaction [Calcium results in increased phosphorylation of CASR protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of WNT5A protein]; CASR protein affects the reaction [Nickel results in increased abundance of Calcium]; CASR protein promotes the reaction [TRPC6 protein results in increased uptake of Calcium]; chelerythrine inhibits the reaction [CASR protein results in increased uptake of Calcium]; Flufenamic Acid promotes the reaction [CASR protein results in increased uptake of Calcium]; Lanthanum inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]; Lanthanum inhibits the reaction [CASR protein results in increased uptake of Calcium]; methyl-beta-cyclodextrin inhibits the reaction [CASR protein results in increased uptake of Calcium]; N-(2-chlorophenylpropyl)-1-(3-methoxyphenyl)ethylamine affects the reaction [CASR gene mutant form results in increased susceptibility to Calcium]; N-(2-chlorophenylpropyl)-1-(3-methoxyphenyl)ethylamine promotes the reaction [CASR protein results in increased susceptibility to Calcium]; NPS R-467 promotes the reaction [Calcium results in increased phosphorylation of CASR protein]; Pertussis Toxin inhibits the reaction [CASR protein results in increased uptake of Calcium]
Calcium affects the expression of CASR mRNA; Calcium affects the expression of CASR protein
CASR protein mutant form results in decreased susceptibility to Calcium
CASR gene mutant form results in increased susceptibility to Calcium; CASR protein mutant form results in increased susceptibility to Calcium
CTD PMID:7874174 PMID:9011580 PMID:10231437 PMID:11071898 PMID:11089548 More... NCBI chr 3:122,183,668...122,291,629
Ensembl chr 3:122,183,668...122,291,629
JBrowse link
G CAT catalase multiple interactions EXP
ISO
CAT protein inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; CAT protein inhibits the reaction [Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]]
[Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in decreased activity of CAT protein]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in decreased activity of CAT protein]; [Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of CAT protein]; Calcium affects the reaction [sodium arsenite results in decreased activity of CAT protein]
CTD PMID:21127073 PMID:22534743 PMID:24184500 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CAV1 caveolin 1 affects transport ISO CAV1 protein affects the transport of Calcium CTD PMID:16428350 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179
JBrowse link
G CAV3 caveolin 3 multiple interactions EXP CAV3 protein affects the reaction [Potassium Chloride results in increased uptake of Calcium] CTD PMID:21294223 NCBI chr 3:8,733,802...8,746,758
Ensembl chr 3:8,733,802...8,841,808
JBrowse link
G CBFB core-binding factor subunit beta affects expression ISO Calcium affects the expression of CBFB mRNA CTD PMID:15913539 NCBI chr16:67,029,149...67,101,058
Ensembl chr16:67,028,984...67,101,058
JBrowse link
G CCL11 C-C motif chemokine ligand 11 increases uptake EXP CCL11 protein results in increased uptake of Calcium CTD PMID:10984371 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334
JBrowse link
G CCL13 C-C motif chemokine ligand 13 increases uptake EXP CCL13 protein results in increased uptake of Calcium CTD PMID:10984371 NCBI chr17:34,356,480...34,358,610
Ensembl chr17:34,356,480...34,358,610
JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions
increases abundance
increases uptake
EXP montelukast inhibits the reaction [CCL2 protein results in increased abundance of Calcium]; Piperidines analog inhibits the reaction [CCL2 protein results in increased uptake of Calcium]; resveratrol inhibits the reaction [CCL2 protein affects the localization of Calcium] CTD PMID:10843593 PMID:10984371 PMID:16212921 PMID:16771778 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
JBrowse link
G CCL3 C-C motif chemokine ligand 3 multiple interactions EXP resveratrol inhibits the reaction [CCL3 protein affects the localization of Calcium] CTD PMID:16212921 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
JBrowse link
G CCL5 C-C motif chemokine ligand 5 increases uptake EXP CCL5 protein results in increased uptake of Calcium CTD PMID:10984371 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CCL7 C-C motif chemokine ligand 7 increases uptake
multiple interactions
EXP CCL7 protein results in increased uptake of Calcium
Piperidines analog inhibits the reaction [CCL7 protein results in increased uptake of Calcium]
CTD PMID:10843593 PMID:10984371 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242
JBrowse link
G CCND1 cyclin D1 affects expression
increases expression
ISO
EXP
Calcium affects the expression of CCND1 mRNA
Calcium results in increased expression of CCND1 mRNA
CTD PMID:15913539 PMID:24658506 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CCR10 C-C motif chemokine receptor 10 affects abundance EXP CCR10 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr17:42,678,889...42,681,843
Ensembl chr17:42,678,889...42,683,917
JBrowse link
G CCR4 C-C motif chemokine receptor 4 affects abundance EXP CCR4 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr 3:32,951,555...32,956,349
Ensembl chr 3:32,951,644...32,956,349
JBrowse link
G CCR8 C-C motif chemokine receptor 8 affects abundance EXP CCR8 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr 3:39,329,709...39,333,680
Ensembl chr 3:39,329,709...39,333,680
JBrowse link
G CCR9 C-C motif chemokine receptor 9 affects abundance EXP CCR9 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr 3:45,886,064...45,903,174
Ensembl chr 3:45,886,509...45,903,174
JBrowse link
G CD28 CD28 molecule multiple interactions
increases abundance
EXP 1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [CD28 protein results in increased abundance of Calcium]; 2-aminoethoxydiphenylborane inhibits the reaction [CD28 protein results in increased abundance of Calcium]; 5-diisopropoxyphosphoryl-5-methyl-1-pyrroline-N-oxide inhibits the reaction [CD28 protein results in increased abundance of Calcium]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [CD28 protein results in increased abundance of Calcium] CTD PMID:14607919 NCBI chr 2:203,706,509...203,739,756
Ensembl chr 2:203,706,475...203,738,912
JBrowse link
G CD38 CD38 molecule multiple interactions ISO CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]; CD38 protein inhibits the reaction [CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]] CTD PMID:20200208 NCBI chr 4:15,778,328...15,853,232
Ensembl chr 4:15,778,275...15,853,232
JBrowse link
G CDC42 cell division cycle 42 multiple interactions ISO Calcium promotes the reaction [PAFAH1B1 protein binds to IQGAP1 protein binds to CDC42 protein] CTD PMID:16369480 NCBI chr 1:22,052,709...22,101,360
Ensembl chr 1:22,025,511...22,101,360
JBrowse link
G CDC42BPB CDC42 binding protein kinase beta affects expression ISO Calcium affects the expression of CDC42BPB mRNA CTD PMID:15913539 NCBI chr14:102,932,380...103,057,549
Ensembl chr14:102,932,380...103,057,549
JBrowse link
G CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 increases cleavage
multiple interactions
EXP Calcium results in increased cleavage of CDK5R1 protein
calpeptin inhibits the reaction [Calcium results in increased cleavage of CDK5R1 protein]
CTD PMID:18242949 NCBI chr17:32,485,028...32,491,256
Ensembl chr17:32,486,993...32,491,253
JBrowse link
G CEBPB CCAAT enhancer binding protein beta affects expression ISO Calcium affects the expression of CEBPB mRNA CTD PMID:15913539 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668
JBrowse link
G CERK ceramide kinase multiple interactions EXP Calcium affects the reaction [CERK protein results in increased phosphorylation of Ceramides] CTD PMID:16269826 NCBI chr22:46,684,410...46,738,252
Ensembl chr22:46,684,410...46,738,252
JBrowse link
G CFB complement factor B multiple interactions ISO CFD protein affects the reaction [[cobra venom factor co-treated with Magnesium co-treated with Calcium] results in increased cleavage of CFB protein] CTD PMID:11724962 NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,084
JBrowse link
G CFD complement factor D multiple interactions ISO CFD protein affects the reaction [[cobra venom factor co-treated with Magnesium co-treated with Calcium] results in increased cleavage of CFB protein] CTD PMID:11724962 NCBI chr19:859,664...863,641
Ensembl chr19:859,664...863,641
JBrowse link
G CFL1 cofilin 1 multiple interactions EXP [Capsaicin results in decreased phosphorylation of and results in increased activity of CFL1 protein] which results in increased import of Calcium CTD PMID:17303079 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026
JBrowse link
G CHRM1 cholinergic receptor muscarinic 1 multiple interactions EXP
ISO
[Acetylcholine results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; [Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; [Pilocarpine results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; CHRM1 protein promotes the reaction [Methacholine Compounds results in increased abundance of Calcium]
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; 1-oleoyl-2-acetylglycerol promotes the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; [Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; Atropine inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Flufenamic Acid inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Gadolinium inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Lanthanum inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Pirenzepine inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Thapsigargin inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]
[[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; [[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein
CTD PMID:11527950 PMID:11553362 PMID:12456425 PMID:18316702 NCBI chr11:62,908,675...62,921,861
Ensembl chr11:62,908,679...62,921,807
JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO [CHRNA4 protein co-treated with CHRNB2 protein mutant form] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein co-treated with CHRNB2 protein] affects the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein mutant form co-treated with CHRNB2 protein] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine] CTD PMID:12754307 NCBI chr20:63,343,223...63,375,471
Ensembl chr20:63,343,223...63,378,401
JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit multiple interactions EXP
ISO
[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium; [[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] which results in increased uptake of Calcium] inhibits the reaction [CHRNA7 protein results in decreased susceptibility to Okadaic Acid]; [Acetylcholine results in increased activity of CHRNA7 protein] which results in increased uptake of Calcium; [Bungarotoxins binds to and results in increased activity of CHRNA7 protein] which results in increased transport of Calcium; [methyllycaconitine binds to and results in increased activity of CHRNA7 protein] which results in increased transport of Calcium; [Nicotine results in increased activity of CHRNA7 protein] which results in increased transport of Calcium; [PNU-282987 binds to and results in increased activity of CHRNA7 protein] which results in increased uptake of Calcium; Bungarotoxins inhibits the reaction [[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium]; Mecamylamine inhibits the reaction [[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium]; methyllycaconitine inhibits the reaction [[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium]; methyllycaconitine promotes the reaction [[Nicotine results in increased activity of CHRNA7 protein] which results in increased transport of Calcium] CTD PMID:17709503 PMID:21051662 PMID:21715663 NCBI chr15:32,030,462...32,173,018
Ensembl chr15:31,923,438...32,173,018
JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit multiple interactions EXP
ISO
[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium; alpha-conotoxin MII inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium]; Calcium affects the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased susceptibility to Okadaic Acid]; Dihydro-beta-Erythroidine inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium]; Mecamylamine inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium]
[CHRNA4 protein co-treated with CHRNB2 protein mutant form] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein co-treated with CHRNB2 protein] affects the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein mutant form co-treated with CHRNB2 protein] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine]
CTD PMID:12754307 PMID:21715663 NCBI chr 1:154,567,778...154,584,708
Ensembl chr 1:154,567,778...154,580,013
JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 affects expression ISO Calcium affects the expression of CITED2 mRNA CTD PMID:15913539 NCBI chr 6:139,371,807...139,374,648
Ensembl chr 6:139,371,807...139,374,648
JBrowse link
G CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 affects expression ISO Calcium affects the expression of CNNM4 mRNA CTD PMID:15913539 NCBI chr 2:96,760,902...96,811,888
Ensembl chr 2:96,760,902...96,811,874
JBrowse link
G CNR1 cannabinoid receptor 1 multiple interactions ISO [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein] affects the reaction [Potassium Chloride results in increased transport of Calcium]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] affects the reaction [Potassium Chloride results in increased transport of Calcium]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium results in increased transport of Calcium]; Calcium affects the reaction [Potassium Chloride results in decreased expression of CNR1 mRNA]; Calcium affects the reaction [Potassium Chloride results in decreased expression of CNR1 protein]; CNR1 protein affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; CNR1 protein affects the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Pertussis Toxin inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]] CTD PMID:12421626 PMID:14973253 PMID:16412482 NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347
JBrowse link
G CNR2 cannabinoid receptor 2 multiple interactions EXP CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]; Pertussis Toxin inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]]; SR 144528 inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]] CTD PMID:10617657 NCBI chr 1:23,870,515...23,913,362
Ensembl chr 1:23,870,515...23,913,362
JBrowse link
G COL18A1 collagen type XVIII alpha 1 chain affects abundance ISO COL18A1 protein affects the abundance of Calcium CTD PMID:15296943 NCBI chr21:45,405,165...45,513,720
Ensembl chr21:45,405,165...45,513,720
JBrowse link
G COL1A2 collagen type I alpha 2 chain affects abundance ISO COL1A2 protein affects the abundance of Calcium CTD PMID:10913914 NCBI chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227
JBrowse link
G CP ceruloplasmin affects binding
multiple interactions
EXP
ISO
Calcium binds to CP protein
[Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of CP protein]
CTD PMID:17242517 PMID:22534743 NCBI chr 3:149,162,410...149,222,008
Ensembl chr 3:149,162,410...149,221,829
JBrowse link
G CREB1 cAMP responsive element binding protein 1 affects expression
multiple interactions
ISO Calcium affects the expression of CREB1 mRNA
[Estradiol results in increased import of Calcium] which results in increased activity of CREB1 protein; Calcium promotes the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased phosphorylation of CREB1 protein]; Calcium promotes the reaction [Dopamine results in increased phosphorylation of CREB1 protein]
CTD PMID:14622123 PMID:15802184 PMID:15913539 NCBI chr 2:207,529,943...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CSNK1A1 casein kinase 1 alpha 1 affects expression ISO Calcium affects the expression of CSNK1A1 mRNA CTD PMID:15913539 NCBI chr 5:149,492,982...149,551,439
Ensembl chr 5:149,492,982...149,551,471
JBrowse link
G CSNK1G3 casein kinase 1 gamma 3 affects expression ISO Calcium affects the expression of CSNK1G3 mRNA CTD PMID:15913539 NCBI chr 5:123,512,116...123,617,049
Ensembl chr 5:123,512,099...123,617,045
JBrowse link
G CTNNB1 catenin beta 1 increases expression
multiple interactions
EXP Calcium results in increased expression of CTNNB1 mRNA; Calcium results in increased expression of CTNNB1 protein
CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]
CTD PMID:24658506 NCBI chr 3:41,199,422...41,240,445
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G CTSS cathepsin S multiple interactions EXP [CTSS protein results in increased cleavage of and results in decreased activity of CXCL10 protein] which results in decreased uptake of Calcium; [CTSS protein results in increased cleavage of and results in decreased activity of CXCL9 protein] which results in decreased uptake of Calcium; [CTSS protein results in increased cleavage of and results in increased activity of CXCL2 protein] which results in increased uptake of Calcium; [CTSS protein results in increased cleavage of and results in increased activity of CXCL5 protein] which results in increased uptake of Calcium CTD PMID:25833952 NCBI chr 1:150,730,188...150,765,778
Ensembl chr 1:150,730,079...150,765,957
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 increases abundance
multiple interactions
ISO CXCL1 protein results in increased abundance of Calcium
epigallocatechin gallate inhibits the reaction [CXCL1 protein results in increased abundance of Calcium]
CTD PMID:9430702 PMID:15237969 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 multiple interactions EXP [CTSS protein results in increased cleavage of and results in decreased activity of CXCL10 protein] which results in decreased uptake of Calcium; [CXCL10 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium CTD PMID:25833952 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 multiple interactions
increases uptake
EXP resveratrol inhibits the reaction [CXCL12 protein affects the localization of Calcium]
CXCL12 protein results in increased uptake of Calcium
CTD PMID:10984371 PMID:11872090 PMID:16212921 NCBI chr10:44,292,088...44,385,097
Ensembl chr10:44,370,165...44,386,493
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 multiple interactions EXP [CTSS protein results in increased cleavage of and results in increased activity of CXCL2 protein] which results in increased uptake of Calcium; [CXCL2 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium CTD PMID:25833952 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 multiple interactions EXP [CTSS protein results in increased cleavage of and results in increased activity of CXCL5 protein] which results in increased uptake of Calcium; [CXCL5 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium CTD PMID:25833952 NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions
increases uptake
increases abundance
EXP 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[PLA2G1B protein results in increased abundance of Calcium] which results in increased expression of CXCL8 protein]; [CXCL8 protein binds to and results in increased activity of CXCR1 protein] which results in increased abundance of and results in increased activity of Calcium; [CXCL8 protein binds to and results in increased activity of CXCR2 protein] which results in increased abundance of and results in increased activity of Calcium; [PLA2G1B protein results in increased abundance of Calcium] which results in increased expression of CXCL8 protein; Calcium promotes the reaction [Neurotensin results in increased expression of CXCL8 mRNA]; CXCL8 protein affects the localization of and affects the abundance of Calcium; resveratrol inhibits the reaction [CXCL8 protein affects the localization of Calcium]
CXCL8 protein results in increased uptake of Calcium
CXCL8 protein results in increased abundance of Calcium
CTD PMID:10984371 PMID:11298490 PMID:14505796 PMID:15528384 PMID:15748943 More... NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,541...73,743,716
JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 multiple interactions
increases abundance
EXP [[CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium] which results in increased expression of EGR1 mRNA; [CTSS protein results in increased cleavage of and results in decreased activity of CXCL9 protein] which results in decreased uptake of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium
CXCL9 protein results in increased abundance of Calcium
CTD PMID:12517959 PMID:25833952 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509
JBrowse link
G CXCR1 C-X-C motif chemokine receptor 1 multiple interactions
affects abundance
EXP [CXCL8 protein binds to and results in increased activity of CXCR1 protein] which results in increased abundance of and results in increased activity of Calcium
CXCR1 protein affects the abundance of Calcium
CTD PMID:11298490 PMID:12055238 NCBI chr 2:218,162,841...218,166,962
Ensembl chr 2:218,162,841...218,166,962
JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 affects transport
multiple interactions
EXP
ISO
CXCR2 protein affects the transport of Calcium
[CXCL2 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium; [CXCL5 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium; [CXCL8 protein binds to and results in increased activity of CXCR2 protein] which results in increased abundance of and results in increased activity of Calcium
Excitatory Amino Acid Agonists inhibits the reaction [CXCR2 protein affects the localization of Calcium]
CTD PMID:11298490 PMID:15618463 PMID:15914698 PMID:25833952 NCBI chr 2:218,125,294...218,137,253
Ensembl chr 2:218,125,289...218,137,251
JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 affects abundance
multiple interactions
EXP CXCR3 protein affects the abundance of Calcium
[[CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium] which results in increased expression of EGR1 mRNA; [CXCL10 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium
CTD PMID:12055238 PMID:12517959 PMID:25833952 NCBI chr  X:71,615,913...71,618,515
Ensembl chr  X:71,615,916...71,618,511
JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 affects abundance EXP CXCR4 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,118,149
JBrowse link
G CXCR5 C-X-C motif chemokine receptor 5 affects abundance EXP CXCR5 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr11:118,883,892...118,897,787
Ensembl chr11:118,883,892...118,897,787
JBrowse link
G CYCS cytochrome c, somatic multiple interactions
increases secretion
decreases secretion
ISO [Calcium co-treated with Phosphates] affects the localization of CYCS protein; caffeic acid phenethyl ester inhibits the reaction [Calcium results in increased secretion of CYCS protein]; Cyclosporine inhibits the reaction [[Calcium co-treated with Phosphates] affects the localization of CYCS protein]; Nicotine inhibits the reaction [[Calcium co-treated with Phosphates] affects the localization of CYCS protein]; xestospongin C inhibits the reaction [Calcium results in decreased secretion of CYCS protein] CTD PMID:15345483 PMID:15469948 PMID:15985439 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions EXP
ISO
2-aminoethoxydiphenyl borate inhibits the reaction [[oltipraz results in increased abundance of Calcium] which results in increased expression of CYP1A1 mRNA]; [2,3,7,8-tetrachlorodibenzofuran co-treated with Calcium] results in increased expression of CYP1A1 mRNA; [oltipraz results in increased abundance of Calcium] which results in increased expression of CYP1A1 mRNA; Calcium promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; Calcium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]
CTD PMID:1979076 PMID:11959854 PMID:16237193 PMID:23298284 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 multiple interactions EXP
ISO
Calcium promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; Calcium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
CTD PMID:16237193 PMID:19782052 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 affects expression
multiple interactions
ISO Calcium affects the expression of CYP24A1 mRNA
[Calcium co-treated with Calcitriol] affects the expression of CYP24A1 mRNA
CTD PMID:15913539 NCBI chr20:54,145,731...54,174,032
Ensembl chr20:54,153,446...54,173,986
JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 affects expression ISO Calcium affects the expression of CYP27B1 mRNA CTD PMID:15913539 NCBI chr12:57,762,334...57,767,078
Ensembl chr12:57,762,334...57,768,986
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 affects expression
decreases uptake
ISO
EXP
Calcium affects the expression of CYP2E1 mRNA
CYP2E1 protein results in decreased uptake of Calcium
CTD PMID:15913539 PMID:19028543 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 multiple interactions EXP
ISO
[CP 199330 binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; [CP 199331 binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; [CP 265298 binds to and results in decreased activity of CYSLTR1 protein] which results in decreased abundance of Calcium; [CP 288886 binds to and results in decreased activity of CYSLTR1 protein] which results in decreased abundance of Calcium; [Leukotriene C4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [Leukotriene D4 results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [Leukotriene E4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [pranlukast binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; [Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [zafirlukast binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; BAY u9773 inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; CYSLTR1 protein promotes the reaction [Leukotriene D4 results in increased abundance of Calcium]; montelukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; montelukast inhibits the reaction [[Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; pobilukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; pranlukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; verlukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; zafirlukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; zafirlukast inhibits the reaction [[Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; zafirlukast inhibits the reaction [CYSLTR1 protein promotes the reaction [Leukotriene D4 results in increased abundance of Calcium]] CTD PMID:8014876 PMID:9934474 PMID:10391245 PMID:10462554 PMID:10509933 More... NCBI chr  X:78,271,468...78,327,611
Ensembl chr  X:78,271,468...78,327,691
JBrowse link
G CYSLTR2 cysteinyl leukotriene receptor 2 multiple interactions EXP [Leukotriene C4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene C4 results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene D4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene D4 results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene E4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene E4 results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; BAY u9773 inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium] CTD PMID:10851239 PMID:11093801 NCBI chr13:48,653,929...48,711,226
Ensembl chr13:48,653,711...48,711,226
JBrowse link
G DDR1 discoidin domain receptor tyrosine kinase 1 affects expression ISO Calcium affects the expression of DDR1 mRNA CTD PMID:15913539 NCBI chr 6:30,880,958...30,900,156
Ensembl chr 6:30,876,421...30,900,156
JBrowse link
G DMD dystrophin increases abundance
multiple interactions
ISO DMD gene mutant form results in increased abundance of Calcium
Nifedipine inhibits the reaction [DMD gene mutant form results in increased abundance of Calcium]
CTD PMID:24349043 NCBI chr  X:31,119,219...33,339,460
Ensembl chr  X:31,097,677...33,339,609
JBrowse link
G DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 multiple interactions
decreases transport
EXP [DNAJB11 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [DNAJB11 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin; DNAJB11 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium] CTD PMID:26085089 NCBI chr 3:186,570,720...186,585,793
Ensembl chr 3:186,567,403...186,585,800
JBrowse link
G DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 multiple interactions
decreases transport
EXP [DNAJC3 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [DNAJC3 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin; DNAJC3 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium] CTD PMID:26085089 NCBI chr13:95,677,139...95,794,988
Ensembl chr13:95,677,139...95,794,988
JBrowse link
G DRD1 dopamine receptor D1 multiple interactions ISO [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased activity of DRD1 protein] which results in increased abundance of Calcium CTD PMID:14622123 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
JBrowse link
G DRD2 dopamine receptor D2 multiple interactions EXP
ISO
[Norepinephrine binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium; [Quinpirole binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium; Sulpiride inhibits the reaction [[Norepinephrine binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium]; Sulpiride inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium]
[DRD2 protein affects the abundance of Calcium] which results in decreased transport of Barium
CTD PMID:8032591 PMID:11124974 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G DRD3 dopamine receptor D3 increases phosphorylation ISO Calcium results in increased phosphorylation of DRD3 protein CTD PMID:19217379 NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
JBrowse link
G DUSP1 dual specificity phosphatase 1 multiple interactions ISO Calcium affects the reaction [Potassium Chloride results in increased expression of DUSP1 mRNA] CTD PMID:11577072 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195
JBrowse link
G EDN1 endothelin 1 increases abundance
increases uptake
multiple interactions
affects transport
affects localization
ISO
EXP
EDN1 protein results in increased abundance of Calcium
EDN1 protein results in increased uptake of Calcium
EDN1 protein affects the localization of and affects the abundance of Calcium
carvedilol inhibits the reaction [EDN1 protein results in increased import of and results in increased abundance of Calcium]; EDN1 protein affects the abundance of and affects the localization of Calcium; EDN1 protein results in increased import of and results in increased abundance of Calcium; Glucose affects the reaction [EDN1 protein affects the abundance of and affects the localization of Calcium]; Heparin inhibits the reaction [EDN1 protein results in increased abundance of Calcium]
EDN1 protein affects the transport of Calcium
EDN1 protein results in increased transport of and results in increased abundance of Calcium; Propofol inhibits the reaction [EDN1 protein affects the transport of Calcium]
EDN1 protein affects the localization of Calcium
CTD PMID:1443220 PMID:9138053 PMID:11425647 PMID:12628492 PMID:12821678 More... NCBI chr 6:12,256,463...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G EDN2 endothelin 2 increases uptake
multiple interactions
ISO EDN2 protein results in increased uptake of Calcium
EDN2 protein affects the localization of and affects the abundance of Calcium
CTD PMID:11425647 NCBI chr 1:41,478,775...41,484,699
Ensembl chr 1:41,478,775...41,484,683
JBrowse link
G EDN3 endothelin 3 multiple interactions
increases uptake
ISO EDN3 protein affects the localization of and affects the abundance of Calcium
BQ 788 inhibits the reaction [EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium]]; EDN3 protein inhibits the reaction [APP protein results in increased uptake of Calcium]; EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium]
EDN3 protein results in increased uptake of Calcium
CTD PMID:11425647 PMID:12383957 PMID:15695168 NCBI chr20:59,300,415...59,325,992
Ensembl chr20:59,300,443...59,325,992
JBrowse link
G EDNRA endothelin receptor type A affects activity ISO Calcium affects the activity of EDNRA protein CTD PMID:12628492 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954
JBrowse link
G EEF2 eukaryotic translation elongation factor 2 multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of EEF2 mRNA CTD PMID:15913539 NCBI chr19:3,976,056...3,985,463
Ensembl chr19:3,976,056...3,985,463
JBrowse link
G EGF epidermal growth factor increases abundance
multiple interactions
affects expression
increases transport
EXP
ISO
EGF protein results in increased abundance of Calcium
[Calcium co-treated with Calcitriol] affects the expression of EGF mRNA
Calcium affects the expression of EGF mRNA
EGF protein results in increased transport of Calcium
[IGF2 protein co-treated with EGF protein] results in increased import of Calcium
RTKI cpd inhibits the reaction [EGF protein results in increased abundance of Calcium]
CTD PMID:2442157 PMID:11527950 PMID:15913539 PMID:24990931 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
JBrowse link
G EGFR epidermal growth factor receptor multiple interactions ISO Calcium affects the phosphorylation of and affects the expression of EGFR protein CTD PMID:8393775 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G EGR1 early growth response 1 multiple interactions EXP [[CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium] which results in increased expression of EGR1 mRNA; [Ionomycin results in increased abundance of Calcium] which results in increased expression of EGR1 protein CTD PMID:12517959 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions EXP Calcium promotes the reaction [Diclofenac results in increased phosphorylation of EIF2AK3 protein] CTD PMID:26609140 NCBI chr 2:88,556,741...88,627,464
Ensembl chr 2:88,556,741...88,691,518
JBrowse link
G EIF4A2 eukaryotic translation initiation factor 4A2 multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of EIF4A2 mRNA CTD PMID:15913539 NCBI chr 3:186,783,577...186,789,897
Ensembl chr 3:186,783,205...186,789,897
JBrowse link
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:12935885 NCBI chr 8:38,030,534...38,060,365
Ensembl chr 8:38,030,534...38,060,365
JBrowse link
G EPHX2 epoxide hydrolase 2 affects expression ISO Calcium affects the expression of EPHX2 mRNA CTD PMID:15913539 NCBI chr 8:27,491,143...27,597,559
Ensembl chr 8:27,490,781...27,545,564
JBrowse link
G F2 coagulation factor II, thrombin increases abundance
increases localization
multiple interactions
increases uptake
EXP F2 protein results in increased abundance of Calcium
F2 protein results in increased localization of Calcium
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [F2 protein results in increased localization of Calcium]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [F2 protein results in increased localization of Calcium]; Apigenin inhibits the reaction [F2 protein results in increased localization of Calcium]; arsenite inhibits the reaction [F2 protein results in increased abundance of Calcium]; Genistein inhibits the reaction [F2 protein results in increased localization of Calcium]; Nickel inhibits the reaction [F2 protein results in increased uptake of Calcium]; Quercetin inhibits the reaction [F2 protein results in increased localization of Calcium]
CTD PMID:2125206 PMID:19814731 PMID:22244921 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F2R coagulation factor II thrombin receptor multiple interactions ISO [Peptides results in increased activity of F2R protein] which results in increased abundance of Calcium CTD PMID:15086339 NCBI chr 5:76,716,126...76,735,770
Ensembl chr 5:76,716,126...76,735,770
JBrowse link
G F2RL1 F2R like trypsin receptor 1 multiple interactions EXP F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]; PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]] CTD PMID:16793902 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315
JBrowse link
G F2RL3 F2R like thrombin or trypsin receptor 3 multiple interactions EXP
ISO
[alanyl-tyrosyl-prolyl-glycyl-lysyl-phenylalanine binds to and results in increased activity of F2RL3 protein] which results in increased uptake of Calcium
F2RL3 protein affects the localization of and affects the transport of Calcium
CTD PMID:16702038 PMID:17707436 NCBI chr19:16,888,999...16,892,606
Ensembl chr19:16,888,999...16,892,606
JBrowse link
G F8 coagulation factor VIII multiple interactions EXP [Copper co-treated with Calcium] results in increased activity of [F8 protein alternative form binds to F8 protein alternative form]; Calcium results in increased activity of [F8 protein alternative form binds to F8 protein alternative form] CTD PMID:11513607 NCBI chr  X:154,835,792...155,022,723
Ensembl chr  X:154,835,788...155,026,940
JBrowse link
G FASLG Fas ligand multiple interactions
affects localization
ISO bafilomycin A1 inhibits the reaction [FASL protein affects the localization of Calcium]; CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]; CD38 protein inhibits the reaction [CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]]; Ryanodine inhibits the reaction [FASL protein affects the localization of Calcium] CTD PMID:20200208 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
JBrowse link
G FGF1 fibroblast growth factor 1 increases expression ISO Calcium results in increased expression of FGF1 protein CTD PMID:15264218 NCBI chr 5:142,592,178...142,698,070
Ensembl chr 5:142,592,178...142,698,070
JBrowse link
G FGF23 fibroblast growth factor 23 affects expression EXP Calcium affects the expression of FGF23 mRNA; Calcium affects the expression of FGF23 protein CTD PMID:15086938 PMID:16381997 NCBI chr12:4,368,227...4,379,712
Ensembl chr12:4,368,227...4,379,712
JBrowse link
G FGF9 fibroblast growth factor 9 affects expression ISO Calcium affects the expression of FGF9 mRNA CTD PMID:15913539 NCBI chr13:21,671,073...21,704,501
Ensembl chr13:21,671,073...21,704,498
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of FGFR1 mRNA CTD PMID:15913539 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
JBrowse link
G FIS1 fission, mitochondrial 1 affects expression ISO Calcium affects the expression of FIS1 mRNA CTD PMID:15913539 NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316
JBrowse link
G FKBP1A FKBP prolyl isomerase 1A multiple interactions EXP FKBP1A protein inhibits the reaction [Calcium results in increased activity of RYR2 protein] CTD PMID:17872463 NCBI chr20:1,368,977...1,393,172
Ensembl chr20:1,368,977...1,393,164
JBrowse link
G FKBP1B FKBP prolyl isomerase 1B multiple interactions ISO FKBP1B gene mutant form inhibits the reaction [Acetylcholine affects the localization of and affects the abundance of Calcium]; Ryanodine inhibits the reaction [FKBP1B gene mutant form inhibits the reaction [Acetylcholine affects the localization of and affects the abundance of Calcium]] CTD PMID:17261647 NCBI chr 2:24,033,205...24,067,743
Ensembl chr 2:24,049,701...24,063,681
JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme affects expression ISO Calcium affects the expression of FURIN mRNA CTD PMID:15913539 NCBI chr15:90,868,588...90,883,457
Ensembl chr15:90,868,588...90,883,564
JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 multiple interactions
decreases activity
EXP Calcium inhibits the reaction [FXYD2 protein results in increased transport of Deoxyglucose]; Calcium inhibits the reaction [FXYD2 protein results in increased transport of Inulin]
Calcium results in decreased activity of FXYD2 protein
CTD PMID:11533133 NCBI chr11:117,820,057...117,828,089
Ensembl chr11:117,800,844...117,828,698
JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 affects expression ISO Calcium affects the expression of G6PC1 mRNA CTD PMID:15913539 NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438
JBrowse link
G GABBR1 gamma-aminobutyric acid type B receptor subunit 1 multiple interactions
affects expression
EXP
ISO
Calcium promotes the reaction [3-aminopropylphosphinic acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]; Calcium promotes the reaction [CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]]; Calcium promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]
Calcium affects the expression of GABBR1 mRNA
CTD PMID:15627515 PMID:15913539 NCBI chr 6:29,602,230...29,633,183
Ensembl chr 6:29,555,629...29,633,976
JBrowse link
G GABBR2 gamma-aminobutyric acid type B receptor subunit 2 multiple interactions EXP Calcium promotes the reaction [3-aminopropylphosphinic acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]; Calcium promotes the reaction [CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]]; Calcium promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]] CTD PMID:15627515 NCBI chr 9:98,288,104...98,708,935
Ensembl chr 9:98,288,109...98,708,935
JBrowse link
G GAST gastrin multiple interactions EXP Calcium promotes the reaction [Colforsin results in increased secretion of GAST protein]; Calcium promotes the reaction [Terbutaline results in increased secretion of GAST protein] CTD PMID:9277405 NCBI chr17:41,712,331...41,715,969
Ensembl chr17:41,712,331...41,715,969
JBrowse link
G GATA1 GATA binding protein 1 affects expression ISO Calcium affects the expression of GATA1 mRNA CTD PMID:15913539 NCBI chr  X:48,786,590...48,794,311
Ensembl chr  X:48,786,562...48,794,311
JBrowse link
G GC GC vitamin D binding protein affects expression ISO Calcium affects the expression of GC mRNA CTD PMID:15913539 NCBI chr 4:71,741,693...71,805,520
Ensembl chr 4:71,741,696...71,804,041
JBrowse link
G GCG glucagon multiple interactions ISO Calcium affects the reaction [Pyruvic Acid results in increased secretion of GCG protein] CTD PMID:15919803 NCBI chr 2:162,142,882...162,152,247
Ensembl chr 2:162,142,882...162,152,404
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of GCLC mRNA CTD PMID:15913539 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
JBrowse link
G GFAP glial fibrillary acidic protein multiple interactions ISO Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]; Calcium deficiency inhibits the reaction [Ethanol results in increased expression of GFAP protein] CTD PMID:17888892 PMID:21879721 NCBI chr17:44,903,159...44,915,552
Ensembl chr17:44,903,159...44,916,937
JBrowse link
G GHR growth hormone receptor affects expression
multiple interactions
ISO Calcium affects the expression of GHR mRNA
[Calcium co-treated with Calcitriol] affects the expression of GHR mRNA
CTD PMID:15913539 NCBI chr 5:42,423,439...42,721,878
Ensembl chr 5:42,423,439...42,721,878
JBrowse link
G GIPC3 GIPC PDZ domain containing family member 3 affects uptake ISO GIPC3 protein affects the uptake of Calcium CTD PMID:27462107 NCBI chr19:3,585,478...3,593,541
Ensembl chr19:3,585,478...3,593,541
JBrowse link
G GLRX3 glutaredoxin 3 affects response to substance ISO GLRX3 protein affects the susceptibility to Calcium CTD PMID:16809552 NCBI chr10:130,136,391...130,182,877
Ensembl chr10:130,136,391...130,184,521
JBrowse link
G GNAI2 G protein subunit alpha i2 affects expression ISO Calcium affects the expression of GNAI2 mRNA CTD PMID:15913539 NCBI chr 3:50,227,068...50,259,362
Ensembl chr 3:50,226,292...50,259,362
JBrowse link
G GNAS GNAS complex locus multiple interactions ISO [[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium; [[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium CTD PMID:23022524 NCBI chr20:58,839,681...58,911,192
Ensembl chr20:58,839,718...58,911,192
JBrowse link
G GPBAR1 G protein-coupled bile acid receptor 1 multiple interactions EXP
ISO
[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased abundance of Calcium
[[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium; [[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium
CTD PMID:23022524 NCBI chr 2:218,259,496...218,263,861
Ensembl chr 2:218,259,496...218,263,861
JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 multiple interactions ISO Calcium deficiency inhibits the reaction [Excitatory Amino Acid Agonists results in decreased phosphorylation of GRIA1 protein] CTD PMID:28404816 NCBI chr 5:153,490,670...153,813,873
Ensembl chr 5:153,489,615...153,813,869
JBrowse link
G GRIA2 glutamate ionotropic receptor AMPA type subunit 2 multiple interactions ISO Calcium promotes the reaction [PICK1 protein binds to GRIA2 protein] CTD PMID:28404816 NCBI chr 4:157,220,120...157,370,583
Ensembl chr 4:157,204,182...157,366,075
JBrowse link
G GRM1 glutamate metabotropic receptor 1 multiple interactions ISO 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]; [3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium; Flufenamic Acid inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]; GRM1 protein promotes the reaction [Propionates results in increased transport of Calcium]; Ruthenium Red inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium] CTD PMID:14622174 PMID:24582715 NCBI chr 6:146,027,634...146,437,601
Ensembl chr 6:146,027,646...146,437,601
JBrowse link
G GSR glutathione-disulfide reductase multiple interactions ISO [Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in decreased activity of GSR protein]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in decreased activity of GSR protein]; [Carmustine results in decreased activity of GSR protein] which results in increased uptake of Calcium; Calcium affects the reaction [sodium arsenite results in decreased activity of GSR protein] CTD PMID:15321730 PMID:24184500 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G HCAR3 hydroxycarboxylic acid receptor 3 increases abundance
multiple interactions
EXP
ISO
HCAR3 protein results in increased abundance of Calcium
[Nicotinic Acids results in increased activity of HCAR2 protein] which results in increased abundance of Calcium
Pertussis Toxin affects the reaction [HCAR3 protein results in increased abundance of Calcium]
CTD PMID:17008386 PMID:19237584 NCBI chr12:122,714,756...122,716,811
Ensembl chr12:122,714,756...122,716,811
JBrowse link
G HECTD4 HECT domain E3 ubiquitin protein ligase 4 multiple interactions EXP Calcium affects the reaction [HECTD4 gene SNP affects the abundance of Lead] CTD PMID:28212632 NCBI chr12:112,160,195...112,382,431
Ensembl chr12:112,160,188...112,382,439
JBrowse link
G HES1 hes family bHLH transcription factor 1 affects expression ISO Calcium affects the expression of HES1 mRNA CTD PMID:15913539 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732
JBrowse link
G HGF hepatocyte growth factor increases abundance ISO HGF protein results in increased abundance of Calcium CTD PMID:10963052 NCBI chr 7:81,699,006...81,770,438
Ensembl chr 7:81,699,010...81,770,438
JBrowse link
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 affects expression ISO Calcium affects the expression of HMGCS2 mRNA CTD PMID:15913539 NCBI chr 1:119,747,996...119,768,932
Ensembl chr 1:119,748,002...119,768,905
JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions EXP Calcium affects the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA] CTD PMID:21443188 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha affects expression ISO Calcium affects the expression of HNF4A mRNA CTD PMID:15913539 NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,700...44,434,596
JBrowse link
G HNRNPD heterogeneous nuclear ribonucleoprotein D multiple interactions ISO Calcium deficiency promotes the reaction [HNRNPD protein binds to PTH 3' UTR] CTD PMID:18583400 NCBI chr 4:82,352,498...82,373,991
Ensembl chr 4:82,352,498...82,374,503
JBrowse link
G HNRNPU heterogeneous nuclear ribonucleoprotein U affects expression ISO Calcium affects the expression of SP120 mRNA CTD PMID:15913539 NCBI chr 1:244,850,297...244,864,543
Ensembl chr 1:244,840,638...244,864,560
JBrowse link
G HOMER1 homer scaffold protein 1 multiple interactions ISO HOMER1 protein alternative form inhibits the reaction [Caffeine promotes the reaction [RYR2 protein results in increased secretion of Calcium]]; HOMER1 protein alternative form inhibits the reaction [Cyclic ADP-Ribose promotes the reaction [RYR2 protein results in increased secretion of Calcium]] CTD PMID:12887973 NCBI chr 5:79,372,636...79,514,134
Ensembl chr 5:79,372,636...79,514,134
JBrowse link
G HPCA hippocalcin decreases response to substance ISO HPCA protein results in decreased susceptibility to Calcium CTD PMID:12445469 NCBI chr 1:32,885,965...32,894,646
Ensembl chr 1:32,885,994...32,898,441
JBrowse link
G HRH1 histamine receptor H1 multiple interactions
increases abundance
EXP [6-((2-(4-imidazolyl)ethyl)amino)heptanoic acid 4-toluidide binds to and results in increased activity of HRH1 protein] which results in increased abundance of Calcium; [Histamine results in increased activity of HRH1 protein] which results in increased abundance of Calcium; [HRH1 protein binds to Histamine] which results in increased import of Calcium; [HRH1 protein binds to Lidocaine] which results in increased import of Calcium; [HRH1 protein binds to Procaine] which results in increased import of Calcium; [HRH1 protein binds to Tetracaine] which results in increased import of Calcium; fexofenadine inhibits the reaction [[Histamine binds to and results in increased activity of HRH1 protein] which results in increased abundance of Calcium]; HRH1 protein promotes the reaction [Histamine results in increased export of Calcium]; Triprolidine inhibits the reaction [[Histamine results in increased activity of HRH1 protein] which results in increased abundance of Calcium]; Triprolidine inhibits the reaction [HRH1 protein promotes the reaction [Histamine results in increased export of Calcium]]
HRH1 protein results in increased abundance of Calcium
CTD PMID:2419744 PMID:11238657 PMID:11527950 PMID:19443731 PMID:32061592 NCBI chr 3:11,137,238...11,263,557
Ensembl chr 3:11,137,093...11,263,557
JBrowse link
G HRH3 histamine receptor H3 multiple interactions ISO [4-(1H-imidazol-4-ylmethyl)piperidine binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; [Histamine binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; [imetit binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; [Methylhistamines binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; clobenpropit inhibits the reaction [[Methylhistamines binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium] CTD PMID:12706455 NCBI chr20:62,213,845...62,220,278
Ensembl chr20:62,214,960...62,220,278
JBrowse link
G HRH4 histamine receptor H4 multiple interactions EXP 1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine inhibits the reaction [[4-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium]; 1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine inhibits the reaction [[clobenpropit binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium]; [4-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [alpha-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [clobenpropit binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [Histamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [imetit binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [N-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium CTD PMID:11181941 PMID:17507084 NCBI chr18:24,460,637...24,479,974
Ensembl chr18:24,460,637...24,479,961
JBrowse link
G HSD17B12 hydroxysteroid 17-beta dehydrogenase 12 multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of HSD17B12 mRNA CTD PMID:15913539 NCBI chr11:43,576,476...43,856,617
Ensembl chr11:43,680,680...43,856,617
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]] CTD PMID:23184943 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions
decreases transport
EXP [DNAJB11 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [DNAJC3 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [HSPA5 protein binds to SEC61A1 protein] which results in decreased transport of Calcium; [HSPA5 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin CTD PMID:26085089 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A increases activity EXP Calcium results in increased activity of HTR1A protein CTD PMID:11356925 NCBI chr 5:63,957,874...63,962,445
Ensembl chr 5:63,957,874...63,962,507
JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A multiple interactions ISO HTR2A protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium] CTD PMID:16901936 NCBI chr13:46,831,546...46,898,082
Ensembl chr13:46,831,546...46,897,076
JBrowse link
G HTR2B 5-hydroxytryptamine receptor 2B multiple interactions ISO Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK1 protein]; Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK3 protein] CTD PMID:18758753 NCBI chr 2:231,108,230...231,126,172
Ensembl chr 2:231,108,230...231,125,042
JBrowse link
G HTR7 5-hydroxytryptamine receptor 7 multiple interactions ISO HTR7 protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium] CTD PMID:16901936 NCBI chr10:90,738,693...90,858,039
Ensembl chr10:90,740,823...90,858,039
JBrowse link
G IFNG interferon gamma multiple interactions ISO
EXP
KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]]
[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]; [TNF protein co-treated with IFNG protein] promotes the reaction [Diclofenac affects the abundance of Calcium]; Calcium promotes the reaction [[Diclofenac co-treated with IFNG protein] results in increased phosphorylation of STAT1 protein]
CTD PMID:23747339 PMID:26609140 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IFT88 intraflagellar transport 88 multiple interactions
increases uptake
ISO Gadolinium inhibits the reaction [IFT88 protein mutant form results in increased uptake of Calcium]; IFT88 protein affects the reaction [PKD2 protein results in increased uptake of Calcium] CTD PMID:16396941 NCBI chr13:20,566,446...20,691,444
Ensembl chr13:20,567,138...20,691,444
JBrowse link
G IGF1 insulin like growth factor 1 affects expression
multiple interactions
increases import
ISO Calcium affects the expression of IGF1 mRNA
Cobalt inhibits the reaction [IGF1 protein results in increased import of Calcium]; tetramethrin inhibits the reaction [IGF1 protein results in increased import of Calcium]
CTD PMID:1550224 PMID:2460452 PMID:2539779 PMID:15913539 NCBI chr12:102,395,860...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G IGF2 insulin like growth factor 2 multiple interactions
increases import
ISO [IGF2 protein co-treated with EGF protein] results in increased import of Calcium; Cobalt inhibits the reaction [IGF2 protein results in increased import of Calcium]; Lanthanum inhibits the reaction [IGF2 protein results in increased import of Calcium]; Pertussis Toxin inhibits the reaction [IGF2 protein results in increased import of Calcium]; tetramethrin inhibits the reaction [IGF2 protein results in increased import of Calcium] CTD PMID:2442157 PMID:2460452 PMID:2539779 NCBI chr11:2,129,117...2,149,566
Ensembl chr11:2,129,112...2,141,238
JBrowse link
G IGFBP2 insulin like growth factor binding protein 2 affects expression ISO Calcium affects the expression of IGFBP2 mRNA CTD PMID:15913539 NCBI chr 2:216,632,828...216,664,436
Ensembl chr 2:216,632,828...216,664,436
JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 affects expression
decreases degradation
ISO Calcium affects the expression of IGFBP5 mRNA
Calcium results in decreased degradation of IGFBP5 protein
CTD PMID:8894652 PMID:15913539 NCBI chr 2:216,672,105...216,695,549
Ensembl chr 2:216,672,105...216,695,549
JBrowse link
G IL11 interleukin 11 multiple interactions
increases abundance
ISO Flurbiprofen inhibits the reaction [IL11 protein results in increased abundance of Calcium]; IL13 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium]; IL4 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium]; IL6ST protein promotes the reaction [IL11 protein results in increased abundance of Calcium]; Indomethacin inhibits the reaction [IL11 protein results in increased abundance of Calcium]; TNFRSF11B protein inhibits the reaction [IL11 protein results in increased abundance of Calcium] CTD PMID:12110441 NCBI chr19:55,364,382...55,370,463
Ensembl chr19:55,364,382...55,370,463
JBrowse link
G IL13 interleukin 13 multiple interactions ISO IL13 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium] CTD PMID:12110441 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO
EXP
KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]] CTD PMID:23747339 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL4 interleukin 4 multiple interactions ISO IL4 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium] CTD PMID:12110441 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G IL6 interleukin 6 multiple interactions
increases expression
EXP Calcimycin inhibits the reaction [Calcium promotes the reaction [Histamine results in increased expression of IL6 protein]]; Calcium promotes the reaction [Histamine results in increased expression of IL6 protein]; Edetic Acid inhibits the reaction [Calcium promotes the reaction [Histamine results in increased expression of IL6 protein]]
Calcium results in increased expression of IL6 mRNA
CTD PMID:11238657 PMID:20682585 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer multiple interactions ISO IL6ST protein promotes the reaction [IL11 protein results in increased abundance of Calcium] CTD PMID:12110441 NCBI chr 5:55,935,095...55,994,963
Ensembl chr 5:55,935,095...55,995,022
JBrowse link
G ILF3 interleukin enhancer binding factor 3 multiple interactions EXP Calcium affects the reaction [Vanadates results in increased activity of ILF3 protein] CTD PMID:10623810 NCBI chr19:10,654,346...10,692,400
Ensembl chr19:10,654,261...10,692,417
JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 multiple interactions ISO Calcium promotes the reaction [PAFAH1B1 protein binds to IQGAP1 protein binds to CDC42 protein] CTD PMID:16369480 NCBI chr15:90,388,242...90,502,239
Ensembl chr15:90,388,242...90,502,239
JBrowse link
G ITGA2 integrin subunit alpha 2 multiple interactions ISO ITGA2 protein promotes the reaction [[Dinoprostone co-treated with Serotonin] results in increased import of Calcium]; TRPV4 protein promotes the reaction [ITGA2 protein promotes the reaction [[Dinoprostone co-treated with Serotonin] results in increased import of Calcium]] CTD PMID:18234883 NCBI chr 5:52,989,352...53,094,779
Ensembl chr 5:52,989,340...53,094,779
JBrowse link
G ITGB1BP2 integrin subunit beta 1 binding protein 2 multiple interactions EXP
ISO
Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to SUGT1 protein]]
Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]]
CTD PMID:23184943 NCBI chr  X:71,301,750...71,305,371
Ensembl chr  X:71,301,750...71,305,371
JBrowse link
G ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 multiple interactions EXP Calcium promotes the reaction [ITIH1 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr 3:52,777,599...52,792,068
Ensembl chr 3:52,777,595...52,792,068
JBrowse link
G ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 multiple interactions EXP Calcium promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr10:7,703,316...7,749,520
Ensembl chr10:7,703,316...7,749,520
JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 multiple interactions EXP ITPR1 protein promotes the reaction [Acetaldehyde metabolite results in increased abundance of Calcium]; ITPR1 protein promotes the reaction [Ethanol metabolite results in increased abundance of Calcium] CTD PMID:17241155 NCBI chr 3:4,493,348...4,847,506
Ensembl chr 3:4,493,345...4,847,506
JBrowse link
G ITPR2 inositol 1,4,5-trisphosphate receptor type 2 multiple interactions ISO 2-aminoethoxydiphenyl borate inhibits the reaction [[adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium]; [adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium; xestospongin C inhibits the reaction [[adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium] CTD PMID:15201137 NCBI chr12:26,335,352...26,833,197
Ensembl chr12:26,335,352...26,833,194
JBrowse link
G ITPR3 inositol 1,4,5-trisphosphate receptor type 3 affects expression ISO Calcium affects the expression of ITPR3 protein CTD PMID:10963052 NCBI chr 6:33,621,322...33,696,562
Ensembl chr 6:33,620,365...33,696,574
JBrowse link
G IVL involucrin increases expression
multiple interactions
EXP Calcium results in increased expression of IVL mRNA
NPS R-467 promotes the reaction [Calcium results in increased expression of IVL mRNA]
CTD PMID:10469331 NCBI chr 1:152,908,546...152,911,886
Ensembl chr 1:152,908,546...152,911,886
JBrowse link
G JAK2 Janus kinase 2 multiple interactions ISO JAK2 protein promotes the reaction [LEP protein results in increased transport of Calcium] CTD PMID:20107083 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948
JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 increases activity
multiple interactions
ISO Calcium results in increased activity of KCNE1 protein
W 7 inhibits the reaction [Calcium results in increased activity of KCNE1 protein]
CTD PMID:1655403 NCBI chr21:34,446,688...34,512,210
Ensembl chr21:34,446,688...34,512,214
JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO Nimodipine inhibits the reaction [KCNH2 protein affects the abundance of Calcium] CTD PMID:11040061 NCBI chr 7:150,944,956...150,978,321
Ensembl chr 7:150,944,961...150,978,321
JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 multiple interactions
affects abundance
ISO Dantrolene inhibits the reaction [KCNJ11 protein mutant form results in increased abundance of Calcium]; KCNJ11 protein affects the reaction [[Manganese co-treated with Dobutamine] results in increased abundance of Calcium]; W 7 inhibits the reaction [KCNJ11 protein mutant form results in increased abundance of Calcium]
KCNJ11 protein affects the abundance of Calcium
CTD PMID:17189350 NCBI chr11:17,385,246...17,389,346
Ensembl chr11:17,365,172...17,389,331
JBrowse link
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 multiple interactions
increases response to substance
EXP
ISO
[KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium; Lithocholic Acid promotes the reaction [[KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium]
KCNMA1 mRNA alternative form results in increased susceptibility to Calcium
CTD PMID:22123969 PMID:28090300 NCBI chr10:76,869,602...77,637,969
Ensembl chr10:76,869,601...77,638,369
JBrowse link
G KCNMB1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 multiple interactions EXP [KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium; Lithocholic Acid promotes the reaction [[KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium] CTD PMID:22123969 NCBI chr 5:170,374,671...170,389,367
Ensembl chr 5:170,374,671...170,389,634
JBrowse link
G KCNN2 potassium calcium-activated channel subfamily N member 2 increases activity
multiple interactions
EXP Calcium results in increased activity of KCNN2 protein
cyclohexyl-(2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl)amine promotes the reaction [Calcium results in increased activity of KCNN2 protein]
CTD PMID:17486140 NCBI chr 5:114,055,978...114,496,500
Ensembl chr 5:114,055,926...114,496,500
JBrowse link
G KCNN3 potassium calcium-activated channel subfamily N member 3 multiple interactions
increases activity
EXP 6,7-dichloro-1H-indole-2,3-dione 3-oxime promotes the reaction [Calcium results in increased activity of KCNN3 protein]; cyclohexyl-(2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl)amine promotes the reaction [Calcium results in increased activity of KCNN3 protein] CTD PMID:17486140 NCBI chr 1:154,697,455...154,870,281
Ensembl chr 1:154,697,455...154,870,281
JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 affects abundance
multiple interactions
EXP KCNN4 protein affects the abundance of Calcium
KCNN4 protein affects the reaction [Calcium results in increased transport of Potassium]
CTD PMID:11826162 PMID:14985237 NCBI chr19:43,766,533...43,782,139
Ensembl chr19:43,766,533...43,781,257
JBrowse link
G KDR kinase insert domain receptor multiple interactions EXP
ISO
[VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium; TRPC6 protein promotes the reaction [[VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium]
Calcium promotes the reaction [Corticosterone results in decreased expression of KDR protein]
CTD PMID:14551041 PMID:21647420 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595
JBrowse link
G KHSRP KH-type splicing regulatory protein multiple interactions ISO Calcium deficiency inhibits the reaction [KHSRP protein binds to PTH 3' UTR] CTD PMID:18583400 NCBI chr19:6,413,102...6,424,811
Ensembl chr19:6,413,102...6,424,811
JBrowse link
G KISS1 KiSS-1 metastasis suppressor multiple interactions ISO 2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; [KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium; Flufenamic Acid inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin promotes the reaction [2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]] CTD PMID:18948403 NCBI chr 1:204,190,341...204,196,491
Ensembl chr 1:204,190,341...204,196,491
JBrowse link
G KISS1R KISS1 receptor multiple interactions ISO 2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; [KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium; Flufenamic Acid inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin promotes the reaction [2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]] CTD PMID:18948403 NCBI chr19:916,693...921,005
Ensembl chr19:917,287...921,005
JBrowse link
G KL klotho affects abundance
multiple interactions
ISO KL protein affects the abundance of Calcium
KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]]
CTD PMID:11796525 PMID:23747339 NCBI chr13:33,016,063...33,066,143
Ensembl chr13:33,016,423...33,066,143
JBrowse link
G KLK1 kallikrein 1 decreases activity EXP Calcium results in decreased activity of KLK1 protein CTD PMID:15558947 NCBI chr19:50,819,146...50,823,787
Ensembl chr19:50,819,146...50,823,787
JBrowse link
G KLK8 kallikrein related peptidase 8 increases activity EXP Calcium results in increased activity of KLK8 protein CTD PMID:16800733 NCBI chr19:50,996,008...51,001,604
Ensembl chr19:50,996,007...51,002,711
JBrowse link
G KNG1 kininogen 1 multiple interactions
increases abundance
affects abundance
EXP
ISO
BDKRB2 protein affects the reaction [KNG1 protein affects the abundance of Calcium]
KNG1 protein modified form results in increased abundance of Calcium
B 4162 inhibits the reaction [pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]]; BDKRB2 protein affects the reaction [pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]]; CALR protein promotes the reaction [KNG1 protein modified form results in increased abundance of Calcium]; KNG1 protein affects the transport of and affects the localization of Calcium; pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]
[KNG1 protein alternative form co-treated with Calcium] results in increased secretion of CALCA protein; Calcium affects the reaction [KNG1 protein results in increased secretion of Excitatory Amino Acid Agents]
KNG1 protein results in increased abundance of Calcium
CTD PMID:7961812 PMID:8592139 PMID:10535458 PMID:12582005 PMID:16473424 More... NCBI chr 3:186,717,359...186,744,410
Ensembl chr 3:186,717,348...186,744,410
JBrowse link
G KRT1 keratin 1 multiple interactions
increases expression
ISO
EXP
12-Hydroxy-5,8,10,14-eicosatetraenoic Acid inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; 15-hydroxy-5,8,11,13-eicosatetraenoic acid inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; 8-hydroxyeicosatetraenoic acid promotes the reaction [Calcium results in increased expression of KRT1 mRNA]; Masoprocol inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; morin inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; Quercetin inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of KRT1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of KRT1 protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; SB 203580 inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; SB 203580 inhibits the reaction [Calcium results in increased expression of KRT1 protein]; WNT5A protein promotes the reaction [Calcium results in increased expression of KRT1 mRNA]; WNT5A protein promotes the reaction [Calcium results in increased expression of KRT1 protein]
Calcium results in increased expression of KRT1 mRNA; Calcium results in increased expression of KRT1 protein
CTD PMID:12069687 PMID:21524694 PMID:24658506 NCBI chr12:52,674,736...52,680,407
Ensembl chr12:52,674,736...52,680,407
JBrowse link
G LEP leptin affects abundance
multiple interactions
affects secretion
increases transport
affects expression
decreases abundance
ISO LEP protein affects the abundance of Calcium
Calcium deficiency inhibits the reaction [[Glucose co-treated with INS1 protein] results in increased secretion of LEP protein]
Calcium deficiency affects the secretion of LEP protein
LEP protein results in increased transport of Calcium
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [LEP protein results in increased transport of Calcium]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [LEP protein results in increased transport of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [LEP protein results in increased transport of Calcium]; acetovanillone inhibits the reaction [LEP protein affects the abundance of Calcium]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [LEP protein results in increased transport of Calcium]; BQ 788 inhibits the reaction [LEP protein affects the abundance of Calcium]; Calcium promotes the reaction [LEP protein results in increased transport of Calcium]; cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [LEP protein affects the abundance of Calcium]; edelfosine inhibits the reaction [LEP protein results in increased transport of Calcium]; Flufenamic Acid inhibits the reaction [LEP protein results in increased transport of Calcium]; JAK2 protein promotes the reaction [LEP protein results in increased transport of Calcium]; Lanthanum promotes the reaction [LEP protein results in increased transport of Calcium]; LEP protein promotes the reaction [TRPC1 protein results in increased transport of Calcium]; LEP protein promotes the reaction [TRPC4 protein results in increased transport of Calcium]; LEP protein promotes the reaction [TRPC5 protein results in increased transport of Calcium]; wortmannin inhibits the reaction [LEP protein results in increased transport of Calcium]
Calcium affects the expression of LEP mRNA
LEP protein results in decreased abundance of Calcium
CTD PMID:10780946 PMID:14657008 PMID:15913539 PMID:16380530 PMID:20107083 NCBI chr 7:128,241,201...128,257,629
Ensembl chr 7:128,241,278...128,257,629
JBrowse link
G LEPR leptin receptor affects expression ISO Calcium affects the expression of LEPR mRNA CTD PMID:15913539 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559
JBrowse link
G LIF LIF interleukin 6 family cytokine increases abundance ISO LIF protein results in increased abundance of Calcium CTD PMID:11073891 NCBI chr22:30,240,453...30,257,487
Ensembl chr22:30,240,453...30,246,759
JBrowse link
G LORICRIN loricrin cornified envelope precursor protein increases expression
multiple interactions
EXP Calcium results in increased expression of LORICRIN mRNA; Calcium results in increased expression of LORICRIN protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of LORICRIN mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of LORICRIN protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; SB 203580 inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; SB 203580 inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; WNT5A protein promotes the reaction [Calcium results in increased expression of LORICRIN mRNA]; WNT5A protein promotes the reaction [Calcium results in increased expression of LORICRIN protein]
CTD PMID:21524694 PMID:24658506 NCBI chr 1:153,259,635...153,262,125
Ensembl chr 1:153,259,687...153,262,124
JBrowse link
G LYPLA1 lysophospholipase 1 multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of LYPLA1 mRNA CTD PMID:15913539 NCBI chr 8:54,046,367...54,101,997
Ensembl chr 8:54,046,367...54,102,017
JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 multiple interactions ISO [Sumatriptan results in increased abundance of Calcium] inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA]; Calcium inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA] CTD PMID:12574409 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,544
JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 affects expression ISO Calcium affects the expression of MAP2K2 mRNA CTD PMID:15913539 NCBI chr19:4,090,321...4,124,184
Ensembl chr19:4,090,321...4,124,122
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 increases phosphorylation
multiple interactions
EXP
ISO
Calcium results in increased phosphorylation of MAPK1 protein
Calcium promotes the reaction [Diclofenac results in increased phosphorylation of MAPK1 protein]
Calcium affects the reaction [Ptychodiscus brevis T2 toxin affects the phosphorylation of MAPK1 protein]; Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK1 protein]
Calcium deficiency inhibits the reaction [Carbachol results in increased phosphorylation of and results in increased activity of MAPK1 protein]
CTD PMID:10660688 PMID:15086530 PMID:16877402 PMID:17537980 PMID:18758753 More... NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK14 mitogen-activated protein kinase 14 affects expression ISO Calcium affects the expression of MAPK14 mRNA CTD PMID:15913539 NCBI chr 6:36,027,711...36,122,964
Ensembl chr 6:36,027,677...36,111,236
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 increases phosphorylation
multiple interactions
EXP
ISO
Calcium results in increased phosphorylation of MAPK3 protein
Calcium promotes the reaction [Diclofenac results in increased phosphorylation of MAPK3 protein]
Calcium deficiency inhibits the reaction [Carbachol results in increased phosphorylation of and results in increased activity of MAPK3 protein]
Calcium affects the reaction [Ptychodiscus brevis T2 toxin affects the phosphorylation of MAPK3 protein]; Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]; Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK3 protein]
CTD PMID:10660688 PMID:15086530 PMID:16877402 PMID:17537980 PMID:18758753 More... NCBI chr16:30,114,105...30,123,309
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPK4 mitogen-activated protein kinase 4 affects expression ISO Calcium affects the expression of MAPK4 mRNA CTD PMID:15913539 NCBI chr18:50,559,772...50,731,826
Ensembl chr18:50,560,087...50,731,826
JBrowse link
G MARCO macrophage receptor with collagenous structure multiple interactions EXP Calcium promotes the reaction [titanium dioxide binds to MARCO protein] CTD PMID:18836211 NCBI chr 2:118,942,180...118,994,664
Ensembl chr 2:118,942,194...118,994,660
JBrowse link
G MCOLN1 mucolipin TRP cation channel 1 multiple interactions EXP [NAADP results in increased activity of MCOLN1 protein] which affects the localization of Calcium CTD PMID:21613607 NCBI chr19:7,522,624...7,534,009
Ensembl chr19:7,522,624...7,534,009
JBrowse link
G MCU mitochondrial calcium uniporter affects localization ISO MCU protein affects the localization of Calcium CTD PMID:22829870 NCBI chr10:72,692,143...72,887,694
Ensembl chr10:72,692,131...72,887,694
JBrowse link
G MGP matrix Gla protein multiple interactions
affects expression
affects binding
EXP
ISO
[Calcium binds to MGP protein] which binds to and results in decreased activity of BMP4 protein; [Edetic Acid inhibits the reaction [Calcium binds to MGP protein]] inhibits the reaction [MGP protein binds to BMP4 protein]; Edetic Acid inhibits the reaction [Calcium binds to MGP protein]
Calcium affects the expression of MGP mRNA
CTD PMID:15913539 PMID:18369157 NCBI chr12:14,880,864...14,885,854
Ensembl chr12:14,880,864...14,885,857
JBrowse link
G MMP1 matrix metallopeptidase 1 affects expression EXP Calcium affects the expression of MMP1 mRNA; Calcium affects the expression of MMP1 protein CTD PMID:17508023 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160
JBrowse link
G MTOR mechanistic target of rapamycin kinase multiple interactions ISO Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of MTOR protein] CTD PMID:12935885 NCBI chr 1:11,106,535...11,273,497
Ensembl chr 1:11,106,535...11,262,551
JBrowse link
G MYBPC3 myosin binding protein C3 multiple interactions
increases response to substance
ISO epigallocatechin gallate inhibits the reaction [MYBPC3 gene mutant form results in increased susceptibility to Calcium] CTD PMID:27994558 NCBI chr11:47,331,406...47,352,702
Ensembl chr11:47,331,406...47,352,702
JBrowse link
G MYH7 myosin heavy chain 7 increases transport EXP MYH7 gene mutant form results in increased transport of Calcium CTD PMID:29741611 NCBI chr14:23,412,740...23,435,677
Ensembl chr14:23,412,740...23,435,660
JBrowse link
G MYL2 myosin light chain 2 multiple interactions EXP Calcium affects the reaction [MYL2 gene SNP affects the abundance of Lead] CTD PMID:28212632 NCBI chr12:110,910,845...110,920,579
Ensembl chr12:110,910,819...110,921,443
JBrowse link
G MYL3 myosin light chain 3 affects expression ISO Calcium affects the expression of MYL3 mRNA CTD PMID:15913539 NCBI chr 3:46,857,872...46,863,444
Ensembl chr 3:46,835,111...46,882,172
JBrowse link
G MYL9 myosin light chain 9 multiple interactions
affects phosphorylation
decreases phosphorylation
ISO [[Calcium results in increased activity of MYLK protein] which results in increased phosphorylation of MYL9 protein] which results in decreased secretion of REN protein; [CACNA1D protein results in increased uptake of Calcium] which results in increased phosphorylation of MYL9 protein; [Escin affects the susceptibility to Calcium] which results in increased phosphorylation of MYL9 protein; Glycodeoxycholic Acid inhibits the reaction [[Escin affects the susceptibility to Calcium] which results in increased phosphorylation of MYL9 protein]; Y 27632 inhibits the reaction [[Escin affects the susceptibility to Calcium] which results in increased phosphorylation of MYL9 protein]
Calcium affects the phosphorylation of MYL9 protein
Calcium deficiency results in decreased phosphorylation of MYL9 protein
CTD PMID:7503253 PMID:9618396 PMID:17272349 PMID:29660437 NCBI chr20:36,541,519...36,551,447
Ensembl chr20:36,541,497...36,551,447
JBrowse link
G MYLK myosin light chain kinase increases activity
multiple interactions
EXP
ISO
Calcium deficiency results in increased activity of MYLK protein; Calcium results in increased activity of MYLK protein
[[Calcium results in increased activity of MYLK protein] which results in increased phosphorylation of MYL9 protein] which results in decreased secretion of REN protein
ML 7 inhibits the reaction [Calcium deficiency results in increased activity of MYLK protein]
CTD PMID:9618396 PMID:10640419 PMID:11054866 NCBI chr 3:123,610,049...123,884,332
Ensembl chr 3:123,610,049...123,884,332
JBrowse link
G MYO1B myosin IB increases activity ISO Calcium deficiency results in increased activity of MYO1B protein CTD PMID:10419463 NCBI chr 2:191,245,400...191,425,386
Ensembl chr 2:191,245,185...191,425,389
JBrowse link
G MYO5A myosin VA affects activity ISO Calcium affects the activity of MYO5A protein CTD PMID:10660602 NCBI chr15:52,307,283...52,529,050
Ensembl chr15:52,307,283...52,529,050
JBrowse link
G NAIP NLR family apoptosis inhibitory protein decreases response to substance ISO NAIP protein results in decreased susceptibility to Calcium CTD PMID:12445469 NCBI chr 5:70,968,166...71,025,339
Ensembl chr 5:70,968,166...71,025,339
JBrowse link
G NCF1 neutrophil cytosolic factor 1 affects abundance ISO NCF1 protein affects the abundance of Calcium CTD PMID:16280459 NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,773,962...74,789,376
JBrowse link
G NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of NDUFS1 mRNA CTD PMID:15913539 NCBI chr 2:206,114,817...206,159,444
Ensembl chr 2:206,114,817...206,159,509
JBrowse link
G NEDD4 NEDD4 E3 ubiquitin protein ligase affects expression ISO Calcium affects the expression of NEDD4 mRNA CTD PMID:15913539 NCBI chr15:55,826,917...55,993,612
Ensembl chr15:55,826,922...55,993,660
JBrowse link
G NEDD4L NEDD4 like E3 ubiquitin protein ligase multiple interactions ISO [NEDD4L gene mutant form results in increased susceptibility to Sodium, Dietary] which results in increased abundance of Calcium; Thiazides inhibits the reaction [[NEDD4L gene mutant form results in increased susceptibility to Sodium, Dietary] which results in increased abundance of Calcium] CTD PMID:23348737 NCBI chr18:58,044,226...58,401,540
Ensembl chr18:58,044,226...58,401,540
JBrowse link
G NEFL neurofilament light chain multiple interactions ISO Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of NEFL protein]; calpeptin inhibits the reaction [Calcium results in increased degradation of NEFL protein]; Indomethacin inhibits the reaction [Calcium results in increased degradation of NEFL protein] CTD PMID:11071371 PMID:21879721 NCBI chr 8:24,950,955...24,956,612
Ensembl chr 8:24,950,955...24,956,721
JBrowse link
G NEFM neurofilament medium chain multiple interactions ISO Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of NEFM protein] CTD PMID:21879721 NCBI chr 8:24,913,761...24,919,093
Ensembl chr 8:24,913,758...24,919,098
JBrowse link
G NEK9 NIMA related kinase 9 affects expression ISO Calcium affects the expression of NEK9 mRNA CTD PMID:15913539 NCBI chr14:75,079,353...75,127,637
Ensembl chr14:75,079,353...75,127,344
JBrowse link
G NF1 neurofibromin 1 decreases transport ISO NF1 protein results in decreased transport of Calcium CTD PMID:21949590 NCBI chr17:31,094,927...31,377,677
Ensembl chr17:31,094,927...31,382,116
JBrowse link
G NFATC2 nuclear factor of activated T cells 2 multiple interactions ISO 4-methyl-4'-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)-1,2,3-thiadiazole-5-carboxanilide inhibits the reaction [[Muscarine co-treated with Calcium] affects the localization of NFATC2 protein]; 4-methyl-4'-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)-1,2,3-thiadiazole-5-carboxanilide inhibits the reaction [[Thapsigargin co-treated with Calcium] affects the localization of NFATC2 protein]; [Muscarine co-treated with Calcium] affects the localization of NFATC2 protein; [Thapsigargin co-treated with Calcium] affects the localization of NFATC2 protein CTD PMID:24990931 NCBI chr20:51,386,963...51,562,857
Ensembl chr20:51,386,957...51,562,831
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 increases abundance ISO NFE2L2 gene mutant form results in increased abundance of Calcium CTD PMID:29618784 NCBI chr 2:177,230,303...177,265,131
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
G NFKBIA NFKB inhibitor alpha affects expression
multiple interactions
ISO
EXP
Calcium affects the expression of NFKBIA mRNA
Calcium affects the reaction [Morphine inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]
CTD PMID:15913539 PMID:24068670 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,513...35,404,749
JBrowse link
G NGB neuroglobin affects transport EXP NGB protein affects the transport of Calcium CTD PMID:19154338 NCBI chr14:77,265,483...77,271,206
Ensembl chr14:77,265,483...77,271,206
JBrowse link
G NGF nerve growth factor multiple interactions
increases uptake
ISO [NGF protein co-treated with 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester] results in increased uptake of Calcium; [NGF protein co-treated with Adenosine Triphosphate] results in increased uptake of Calcium; cadmium acetate inhibits the reaction [NGF protein results in increased uptake of Calcium]; Cadmium inhibits the reaction [NGF protein results in increased uptake of Calcium]; calmidazolium inhibits the reaction [NGF protein results in increased uptake of Calcium]; Fluphenazine inhibits the reaction [NGF protein results in increased uptake of Calcium]; Nifedipine inhibits the reaction [NGF protein results in increased uptake of Calcium]; Okadaic Acid promotes the reaction [NGF protein results in increased uptake of Calcium]; Staurosporine inhibits the reaction [NGF protein results in increased uptake of Calcium] CTD PMID:1374475 NCBI chr 1:115,285,915...115,338,253
Ensembl chr 1:115,285,904...115,338,770
JBrowse link
G NOA1 nitric oxide associated 1 multiple interactions ISO [Tamoxifen results in increased abundance of Calcium] which results in increased activity of NOA1 protein CTD PMID:17283165 NCBI chr 4:56,963,350...56,977,606
Ensembl chr 4:56,963,350...56,977,606
JBrowse link
G NOS1 nitric oxide synthase 1 multiple interactions ISO [Calcium binds to CALM1 protein] promotes the reaction [NOS1 protein results in increased chemical synthesis of Nitric Oxide]; [Calcium binds to CALM1 protein] which binds to and affects the folding of and results in increased activity of NOS1 protein CTD PMID:17098364 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
JBrowse link
G NOS3 nitric oxide synthase 3 affects response to substance
increases activity
multiple interactions
ISO
EXP
NOS3 protein affects the susceptibility to Calcium
Calcium results in increased activity of NOS3 protein
Calcium affects the reaction [Polycyclic Aromatic Hydrocarbons results in increased expression of and results in increased activity of NOS3 protein]; Calcium deficiency inhibits the reaction [Digitoxin results in increased activity of NOS3 protein]; Calcium deficiency inhibits the reaction [ginsenoside Re results in increased phosphorylation of NOS3 protein]
CTD PMID:15183461 PMID:17403420 PMID:17490654 PMID:19380615 PMID:19446813 More... NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G NOX1 NADPH oxidase 1 multiple interactions ISO 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid inhibits the reaction [NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]]; NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]] CTD PMID:24912985 NCBI chr  X:100,843,324...100,874,359
Ensembl chr  X:100,843,324...100,874,359
JBrowse link
G NPPC natriuretic peptide C increases uptake
multiple interactions
ISO NPPC protein results in increased uptake of Calcium
Ammonia inhibits the reaction [NPPC protein results in increased uptake of Calcium]; Nimodipine inhibits the reaction [NPPC protein results in increased uptake of Calcium]
CTD PMID:18222015 NCBI chr 2:231,921,809...231,926,405
Ensembl chr 2:231,921,809...231,926,396
JBrowse link
G NPR1 natriuretic peptide receptor 1 affects expression ISO Calcium affects the expression of NPR1 mRNA CTD PMID:15913539 NCBI chr 1:153,678,649...153,693,992
Ensembl chr 1:153,678,688...153,693,992
JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 affects expression ISO Calcium affects the expression of NR0B2 mRNA CTD PMID:15913539 NCBI chr 1:26,911,489...26,914,110
Ensembl chr 1:26,911,489...26,913,975
JBrowse link
G NR1D2 nuclear receptor subfamily 1 group D member 2 affects expression ISO Calcium affects the expression of NR1D2 mRNA CTD PMID:15913539 NCBI chr 3:23,945,286...23,980,618
Ensembl chr 3:23,945,286...23,980,617
JBrowse link
G NRXN1 neurexin 1 multiple interactions ISO Calcium affects the reaction [alpha-latrotoxin binds to NRXN1 protein]; Calcium affects the reaction [black widow spider venom binds to NRXN1 protein] CTD PMID:9430716 NCBI chr 2:49,918,503...51,032,132
Ensembl chr 2:49,918,503...51,225,575
JBrowse link
G NUCB2 nucleobindin 2 multiple interactions ISO KT 5720 inhibits the reaction [NUCB2 protein results in increased import of Calcium] CTD PMID:17627999 NCBI chr11:17,260,337...17,349,980
Ensembl chr11:17,208,153...17,349,980
JBrowse link
G OCLN occludin multiple interactions EXP Calcium deficiency inhibits the reaction [TJP1 protein binds to OCLN protein] CTD PMID:11054866 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104
JBrowse link
G OPRM1 opioid receptor mu 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Calcium] inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]] CTD PMID:18652891 NCBI chr 6:154,010,496...154,246,867
Ensembl chr 6:154,010,496...154,246,867
JBrowse link
G OR1D2 olfactory receptor family 1 subfamily D member 2 multiple interactions EXP [bourgeonal binds to and results in increased activity of OR1D2 protein] which results in increased abundance of Calcium CTD PMID:21454470 NCBI chr17:3,088,484...3,104,422
Ensembl chr17:3,088,484...3,104,422
JBrowse link
G OR5D18 olfactory receptor family 5 subfamily D member 18 multiple interactions ISO [ethyl vanillin binds to and results in increased activity of OLFR73 protein] which results in increased transport of Calcium; [Eugenol binds to and results in increased activity of OLFR73 protein] which results in increased transport of Calcium; [Eugenol binds to OLFR73 protein] which results in increased transport of Calcium; [isomethyleugenol binds to and results in decreased activity of OLFR73 protein] which results in decreased transport of Calcium; isomethyleugenol inhibits the reaction [[Eugenol binds to OLFR73 protein] which results in increased transport of Calcium] CTD PMID:14685265 PMID:15716417 NCBI chr11:55,819,630...55,820,571
Ensembl chr11:55,819,630...55,820,571
JBrowse link
G ORAI1 ORAI calcium release-activated calcium modulator 1 multiple interactions
increases uptake
ISO [Calcium affects the activity of and affects the localization of STIM1 protein] which affects the activity of ORAI1 protein
ORAI1 protein results in increased uptake of Calcium
CTD PMID:23212906 PMID:24990931 NCBI chr12:121,626,550...121,642,040
Ensembl chr12:121,626,550...121,642,677
JBrowse link
G OXT oxytocin/neurophysin I prepropeptide multiple interactions EXP
ISO
OXT protein promotes the reaction [TRPC3 protein results in increased transport of Calcium]
[Thapsigargin results in increased transport of Calcium] which results in increased secretion of OXT protein
CTD PMID:12700192 PMID:22028774 NCBI chr20:3,068,871...3,072,517
Ensembl chr20:3,071,620...3,072,517
JBrowse link
G P2RX3 purinergic receptor P2X 3 multiple interactions EXP [alpha,beta-methyleneadenosine 5'-triphosphate binds to and results in increased activity of P2RX3 protein] which results in increased abundance of Calcium; Trichloroethylene inhibits the reaction [[alpha,beta-methyleneadenosine 5'-triphosphate binds to and results in increased activity of P2RX3 protein] which results in increased abundance of Calcium] CTD PMID:12694404 NCBI chr11:57,335,943...57,372,399
Ensembl chr11:57,338,352...57,372,396
JBrowse link
G P2RX7 purinergic receptor P2X 7 multiple interactions EXP [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium; KN 62 inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium]; protoberberine analog inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium] CTD PMID:21320518 NCBI chr12:121,132,819...121,188,032
Ensembl chr12:121,132,819...121,188,032
JBrowse link
G P2RY1 purinergic receptor P2Y1 multiple interactions EXP
ISO
[Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein] which results in increased abundance of Calcium; Calcium affects the reaction [P2RY1 protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; Trichloroethylene inhibits the reaction [[Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein] which results in increased abundance of Calcium]
[N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate binds to and results in decreased activity of P2RY1 protein] inhibits the reaction [Adenosine Triphosphate results in increased uptake of Calcium]
CTD PMID:12694404 PMID:16236484 PMID:16973929 NCBI chr 3:152,835,131...152,841,439
Ensembl chr 3:152,835,131...152,841,439
JBrowse link
G P2RY2 purinergic receptor P2Y2 multiple interactions
affects response to substance
EXP
ISO
[Adenosine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Calcium
P2RY2 protein affects the susceptibility to Calcium
[Adenosine Triphosphate results in increased activity of P2RY2 protein] which results in increased uptake of Calcium; Go 6976 promotes the reaction [P2RY2 protein results in increased uptake of Calcium]; Tetradecanoylphorbol Acetate inhibits the reaction [P2RY2 protein results in increased uptake of Calcium]
CTD PMID:11527950 PMID:17003265 PMID:18343036 NCBI chr11:73,218,281...73,242,427
Ensembl chr11:73,218,281...73,242,427
JBrowse link
G P2RY4 pyrimidinergic receptor P2Y4 multiple interactions EXP [Adenosine Triphosphate binds to and results in increased activity of P2RY4 protein] which results in increased abundance of Calcium; Trichloroethylene inhibits the reaction [[Adenosine Triphosphate binds to and results in increased activity of P2RY4 protein] which results in increased abundance of Calcium] CTD PMID:12694404 NCBI chr  X:70,258,166...70,260,204
Ensembl chr  X:70,258,166...70,260,204
JBrowse link
G P4HB prolyl 4-hydroxylase subunit beta multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of P4HB mRNA CTD PMID:15913539 NCBI chr17:81,843,159...81,860,535
Ensembl chr17:81,843,159...81,860,856
JBrowse link
G PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 increases abundance
multiple interactions
EXP
ISO
PAFAH1B1 protein results in increased abundance of Calcium
Calcium promotes the reaction [PAFAH1B1 protein binds to IQGAP1 protein binds to CDC42 protein]
PKD1 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium]; PKD2 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium]
CTD PMID:15001556 PMID:16369480 NCBI chr17:2,593,210...2,685,617
Ensembl chr17:2,593,210...2,685,615
JBrowse link
G PARG poly(ADP-ribose) glycohydrolase multiple interactions ISO PARG protein promotes the reaction [Hydrogen Peroxide results in increased uptake of Calcium] CTD PMID:20878536 NCBI chr10:49,818,279...49,942,027
Ensembl chr10:49,818,279...49,970,203
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions ISO PARP1 protein promotes the reaction [Hydrogen Peroxide results in increased uptake of Calcium] CTD PMID:20878536 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PASK PAS domain containing serine/threonine kinase multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of PASK mRNA CTD PMID:15913539 NCBI chr 2:241,106,099...241,150,264
Ensembl chr 2:241,106,099...241,150,264
JBrowse link
G PAX6 paired box 6 affects expression ISO Calcium affects the expression of PAX6 mRNA CTD PMID:15913539 NCBI chr11:31,789,026...31,817,961
Ensembl chr11:31,784,779...31,817,961
JBrowse link
G PAX8 paired box 8 affects expression ISO Calcium affects the expression of PAX8 mRNA CTD PMID:15913539 NCBI chr 2:113,215,997...113,278,921
Ensembl chr 2:113,215,997...113,278,921
JBrowse link
G PCDH19 protocadherin 19 affects binding EXP Calcium binds to PCDH19 protein CTD PMID:18469813 NCBI chr  X:100,291,644...100,410,273
Ensembl chr  X:100,291,644...100,410,273
JBrowse link
G PDGFB platelet derived growth factor subunit B increases import EXP PDGFB protein results in increased import of Calcium CTD PMID:19576918 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982
JBrowse link
G PDK1 pyruvate dehydrogenase kinase 1 affects abundance
multiple interactions
ISO
EXP
PDK1 protein affects the abundance of Calcium
PDK1 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester affects the reaction [PDK1 protein affects the abundance of Calcium]; [PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium; Adenosine Triphosphate promotes the reaction [PDK1 protein affects the abundance of Calcium]; PDK1 protein affects the reaction [Thapsigargin affects the abundance of Calcium]; tubacin affects the reaction [[PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium]; tubacin affects the reaction [PDK1 protein affects the abundance of Calcium]; tubacin inhibits the reaction [PDK1 protein affects the reaction [Thapsigargin affects the abundance of Calcium]]
CTD PMID:28634229 PMID:28887310 NCBI chr 2:172,555,373...172,672,698
Ensembl chr 2:172,555,373...172,608,669
JBrowse link
G PDZD3 PDZ domain containing 3 multiple interactions ISO [[USP2 gene mutant form results in increased expression of PDZD3 protein] which results in increased activity of TRPV6 protein] which results in increased uptake of Calcium CTD PMID:26756164 NCBI chr11:119,185,457...119,190,218
Ensembl chr11:119,185,457...119,190,223
JBrowse link
G PGP phosphoglycolate phosphatase decreases activity ISO Calcium results in decreased activity of PGP protein CTD PMID:24338473 NCBI chr16:2,211,593...2,214,840
Ensembl chr16:2,211,593...2,214,840
JBrowse link
G PICK1 protein interacting with PRKCA 1 multiple interactions ISO Calcium affects the reaction [PICK1 protein binds to AGO2 protein]; Calcium deficiency inhibits the reaction [Excitatory Amino Acid Agonists inhibits the reaction [PICK1 protein binds to AGO2 protein]]; Calcium promotes the reaction [PICK1 protein binds to GRIA2 protein] CTD PMID:28404816 NCBI chr22:38,056,311...38,075,704
Ensembl chr22:38,056,311...38,075,701
JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta affects transport ISO PIK3CB protein affects the transport of Calcium CTD PMID:11597992 NCBI chr 3:138,652,698...138,834,928
Ensembl chr 3:138,652,698...138,834,928
JBrowse link
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta affects transport ISO PIK3CD protein affects the transport of Calcium CTD PMID:16179367 NCBI chr 1:9,629,889...9,729,114
Ensembl chr 1:9,651,731...9,729,114
JBrowse link
G PIP5K1B phosphatidylinositol-4-phosphate 5-kinase type 1 beta affects expression ISO Calcium affects the expression of PIP5K1B mRNA CTD PMID:15913539 NCBI chr 9:68,705,240...69,009,176
Ensembl chr 9:68,705,240...69,009,176
JBrowse link
G PKD1 polycystin 1, transient receptor potential channel interacting multiple interactions EXP
ISO
PKD1 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium]
PKD1 protein affects the reaction [Caffeine affects the abundance of Calcium]; PKD1 protein affects the reaction [Thapsigargin affects the abundance of Calcium]
CTD PMID:15001556 PMID:18679710 NCBI chr16:2,088,708...2,135,898
Ensembl chr16:2,088,708...2,135,898
JBrowse link
G PKD2 polycystin 2, transient receptor potential cation channel increases transport
multiple interactions
EXP
ISO
PKD2 protein results in increased transport of Calcium
PKD2 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium]
IFT88 protein affects the reaction [PKD2 protein results in increased uptake of Calcium]
CTD PMID:15001556 PMID:15100357 PMID:16396941 NCBI chr 4:88,007,635...88,077,779
Ensembl chr 4:88,007,635...88,077,777
JBrowse link
G PKLR pyruvate kinase L/R multiple interactions ISO Calcium inhibits the reaction [Phenylephrine results in decreased activity of PKLR protein] CTD PMID:747652 NCBI chr 1:155,289,293...155,301,438
Ensembl chr 1:155,289,293...155,301,438
JBrowse link
G PLA2G1B phospholipase A2 group IB multiple interactions
increases abundance
EXP 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[PLA2G1B protein results in increased abundance of Calcium] which results in increased expression of CXCL8 protein]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [PLA2G1B protein results in increased abundance of Calcium]; [PLA2G1B protein results in increased abundance of Calcium] which results in increased expression of CXCL8 protein CTD PMID:15528384 NCBI chr12:120,322,115...120,327,779
Ensembl chr12:120,322,115...120,327,779
JBrowse link
G PLA2G2A phospholipase A2 group IIA increases uptake
multiple interactions
ISO PLA2G2A protein results in increased uptake of Calcium
BQ 788 inhibits the reaction [EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium]]; EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium]
CTD PMID:15695168 NCBI chr 1:19,975,431...19,980,434
Ensembl chr 1:19,975,431...19,980,416
JBrowse link
G PLA2G6 phospholipase A2 group VI increases activity
multiple interactions
ISO Calcium deficiency results in increased activity of PLA2G6 protein
6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2H-pyran-2-one inhibits the reaction [[Lipopolysaccharides results in increased expression of and results in increased activity of PLA2G6 protein] which results in increased susceptibility to Calcium]; [Lipopolysaccharides results in increased expression of and results in increased activity of PLA2G6 protein] which results in increased susceptibility to Calcium
CTD PMID:17885217 PMID:21178110 NCBI chr22:38,111,495...38,181,830
Ensembl chr22:38,111,495...38,214,778
JBrowse link
G PLCG2 phospholipase C gamma 2 multiple interactions EXP Calcium promotes the reaction [PLCG2 protein mutant form results in increased chemical synthesis of Inositol Phosphates]; Calcium promotes the reaction [PLCG2 protein results in increased chemical synthesis of Inositol Phosphates] CTD PMID:27542411 NCBI chr16:81,779,291...81,962,685
Ensembl chr16:81,739,097...81,962,685
JBrowse link
G PNOC prepronociceptin decreases abundance ISO PNOC protein results in decreased abundance of Calcium CTD PMID:21039959 NCBI chr 8:28,316,979...28,343,355
Ensembl chr 8:28,316,986...28,343,355
JBrowse link
G PON1 paraoxonase 1 increases activity
multiple interactions
EXP
ISO
Calcium results in increased activity of PON1 protein
[Calcium results in increased activity of PON1 protein] which affects the susceptibility to O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate; [Calcium results in increased activity of PON1 protein] which affects the susceptibility to oxamyl; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Aldicarb; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to methylparaoxon; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Paraoxon
[Calcium co-treated with 1,2-dioleoyl-sn-glycero-3-phosphoglycerol] results in increased stability of PON1 protein; [Calcium co-treated with Oleic Acid] results in increased stability of PON1 protein; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Aldicarb; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to methylparaoxon; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to oxamyl; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Paraoxon; Calcium promotes the reaction [Oleic Acid inhibits the reaction [4-hydroxymercuribenzoate results in decreased activity of PON1 protein]]
CTD PMID:12871208 PMID:27132127 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
JBrowse link
G PON2 paraoxonase 2 affects abundance
multiple interactions
EXP PON2 gene polymorphism affects the abundance of Calcium
Calcium inhibits the reaction [lead acetate results in decreased activity of PON2 protein]
CTD PMID:16141008 PMID:22271317 NCBI chr 7:95,404,862...95,435,028
Ensembl chr 7:95,404,862...95,435,329
JBrowse link
G POU6F1 POU class 6 homeobox 1 affects expression ISO Calcium affects the expression of POU6F1 mRNA CTD PMID:15913539 NCBI chr12:51,186,936...51,219,875
Ensembl chr12:51,186,936...51,217,708
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions ISO [GW 7647 binds to and results in increased activity of PPARA protein] affects the reaction [Glucose affects the abundance of Calcium]; [Oleylethanolamide binds to and results in increased activity of PPARA protein] affects the reaction [Glucose affects the abundance of Calcium]; [pirinixic acid binds to and results in increased activity of PPARA protein] affects the reaction [Glucose affects the abundance of Calcium] CTD PMID:19017711 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,756
JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha affects expression ISO Calcium affects the expression of PPP1CA mRNA CTD PMID:15913539 NCBI chr11:67,398,183...67,401,858
Ensembl chr11:67,398,181...67,421,183
JBrowse link
G PPP1CB protein phosphatase 1 catalytic subunit beta affects expression ISO Calcium affects the expression of PPP1CB mRNA CTD PMID:15913539 NCBI chr 2:28,751,604...28,802,940
Ensembl chr 2:28,751,640...28,802,940
JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A multiple interactions ISO [Egtazic Acid co-treated with Calcium deficiency] results in increased expression of PPP1R15A mRNA CTD PMID:9878749 NCBI chr19:48,872,421...48,876,058
Ensembl chr19:48,872,421...48,876,058
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha affects abundance
affects transport
ISO PPP2CA protein affects the abundance of Calcium
PPP2CA protein affects the transport of Calcium
CTD PMID:15247211 NCBI chr 5:134,194,332...134,226,073
Ensembl chr 5:134,194,332...134,226,073
JBrowse link
G PPP3R1 protein phosphatase 3 regulatory subunit B, alpha multiple interactions
affects response to substance
ISO PPP3R1 gene mutant form inhibits the reaction [ATP2A2 protein affects the transport of Calcium]; PPP3R1 gene mutant form inhibits the reaction [SLC8A1 protein affects the transport of Calcium]
PPP3R1 gene mutant form affects the susceptibility to Calcium
CTD PMID:19700627 NCBI chr 2:68,178,857...68,252,532
Ensembl chr 2:68,178,857...68,256,237
JBrowse link
G PRDX6 peroxiredoxin 6 multiple interactions ISO [Calcium co-treated with Calcitriol] affects the expression of PRDX6 mRNA CTD PMID:15913539 NCBI chr 1:173,477,335...173,488,815
Ensembl chr 1:173,477,330...173,488,815
JBrowse link
G PRKCA protein kinase C alpha multiple interactions
increases response to substance
ISO [Tretinoin co-treated with Calcium] results in increased activity of PRKCA protein
PRKCA protein results in increased susceptibility to Calcium
CTD PMID:12388232 PMID:16114872 NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743
JBrowse link
G PRKCB protein kinase C beta multiple interactions ISO Calcium inhibits the reaction [Chlordecone results in increased activity of PRKCB protein]; Calcium inhibits the reaction [Dicofol results in increased activity of PRKCB protein] CTD PMID:1724372 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611
JBrowse link
G PRKCD protein kinase C delta affects expression ISO Calcium affects the expression of PRKCD mRNA CTD PMID:15913539 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717
JBrowse link
G PRKCE protein kinase C epsilon multiple interactions
increases phosphorylation
affects response to substance
ISO
EXP
PRKCE protein affects the reaction [Oxygen deficiency results in increased abundance of Calcium]
Calcium results in increased phosphorylation of PRKCE protein
chelerythrine inhibits the reaction [Calcium results in increased phosphorylation of PRKCE protein]; PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]]
PRKCE protein affects the susceptibility to Calcium
CTD PMID:15242976 PMID:16793902 PMID:17087917 PMID:21562303 NCBI chr 2:45,651,315...46,187,990
Ensembl chr 2:45,651,345...46,187,990
JBrowse link
G PRKCG protein kinase C gamma multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Calcium] inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]] CTD PMID:18652891 NCBI chr19:53,882,197...53,907,652
Ensembl chr19:53,879,190...53,907,652
JBrowse link
G PRKD1 protein kinase D1 multiple interactions EXP
ISO
PRKD1 promotes the reaction [Capsaicin results in increased uptake of Calcium]
PRKD1 mutant form inhibits the reaction [Capsaicin results in increased uptake of Calcium]
CTD PMID:15471852 NCBI chr14:29,576,479...29,927,847
Ensembl chr14:29,576,479...30,191,898
JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 increases response to substance ISO PRKG1 protein results in increased susceptibility to Calcium CTD PMID:16533816 NCBI chr10:50,990,888...52,298,350
Ensembl chr10:50,990,888...52,298,423
JBrowse link
G PRL prolactin multiple interactions EXP Calcium inhibits the reaction [PRL protein binds to PRLR protein] CTD PMID:6197504 NCBI chr 6:22,287,246...22,302,897
Ensembl chr 6:22,287,244...22,302,826
JBrowse link
G PRLR prolactin receptor affects expression
multiple interactions
ISO
EXP
Calcium affects the expression of PRLR mRNA
Calcium inhibits the reaction [PRL protein binds to PRLR protein]
CTD PMID:6197504 PMID:15913539 NCBI chr 5:35,048,756...35,230,724
Ensembl chr 5:35,048,756...35,230,487
JBrowse link
G PROK2 prokineticin 2 multiple interactions
increases abundance
ISO PROKR1 protein affects the reaction [PROK2 protein results in increased abundance of Calcium] CTD PMID:16793879 PMID:17107623 NCBI chr 3:71,771,655...71,785,148
Ensembl chr 3:71,771,655...71,785,206
JBrowse link
G PROKR1 prokineticin receptor 1 multiple interactions ISO PROKR1 protein affects the reaction [Capsaicin results in increased abundance of Calcium]; PROKR1 protein affects the reaction [PROK2 protein results in increased abundance of Calcium] CTD PMID:16793879 NCBI chr 2:68,643,579...68,658,251
Ensembl chr 2:68,643,579...68,658,251
JBrowse link
G PTAFR platelet activating factor receptor multiple interactions ISO RGS4 protein inhibits the reaction [PTAFR protein affects the localization of and affects the abundance of Calcium] CTD PMID:11297424 NCBI chr 1:28,147,166...28,193,856
Ensembl chr 1:28,147,166...28,193,936
JBrowse link
G PTGDR2 prostaglandin D2 receptor 2 multiple interactions EXP PTGDR2 protein affects the abundance of and affects the localization of Calcium CTD PMID:16256979 NCBI chr11:60,850,933...60,855,950
Ensembl chr11:60,850,933...60,855,950
JBrowse link
G PTGER1 prostaglandin E receptor 1 multiple interactions
increases abundance
ISO 17-phenyltrinorprostaglandin E2 inhibits the reaction [PTGER1 protein results in increased abundance of Calcium] CTD PMID:11809688 NCBI chr19:14,472,466...14,475,354
Ensembl chr19:14,472,466...14,475,354
JBrowse link
G PTGER3 prostaglandin E receptor 3 multiple interactions ISO PTGER3 protein affects the reaction [Dinoprostone results in decreased transport of Calcium]; PTGER3 protein affects the reaction [ONO AE 248 results in decreased transport of Calcium] CTD PMID:12535167 NCBI chr 1:70,852,358...71,047,816
Ensembl chr 1:70,852,353...71,047,808
JBrowse link
G PTGIR prostaglandin I2 receptor multiple interactions EXP [cicaprost results in increased activity of PTGIR protein] which results in increased abundance of Calcium CTD PMID:11895442 NCBI chr19:46,610,040...46,625,097
Ensembl chr19:46,620,468...46,625,089
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 affects expression ISO Calcium affects the expression of PTGS1 mRNA CTD PMID:15913539 NCBI chr 9:122,369,906...122,395,703
Ensembl chr 9:122,370,530...122,395,703
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP
ISO
Calcium affects the reaction [bisperoxovanadium results in increased expression of PTGS2 mRNA]
Calcium deficiency inhibits the reaction [Serotonin results in increased expression of PTGS2 mRNA]
Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]
CTD PMID:12493747 PMID:19782052 PMID:21262218 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G PTH parathyroid hormone multiple interactions
increases stability
increases abundance
decreases abundance
affects metabolic processing
decreases expression
EXP
ISO
[Calcitriol co-treated with Calcium] results in decreased expression of PTH protein; [Cholecalciferol co-treated with Calcium] results in decreased expression of PTH protein
Calcium deficiency results in increased stability of PTH mRNA
Calcium affects the reaction [Aluminum Compounds results in decreased expression of PTH mRNA]; Calcium affects the reaction [Aluminum Compounds results in decreased secretion of PTH protein]; Calcium affects the reaction [Calcitriol results in decreased expression of PTH mRNA]; Calcium affects the reaction [Calcitriol results in decreased secretion of PTH protein]; Calcium deficiency inhibits the reaction [KHSRP protein binds to PTH 3' UTR]; Calcium deficiency promotes the reaction [HNRNPD protein binds to PTH 3' UTR]
PTH protein modified form results in increased abundance of Calcium
PTH protein results in decreased abundance of Calcium
PTH protein affects the metabolism of Calcium
Calcium results in decreased expression of PTH protein
CTD PMID:80633 PMID:6330156 PMID:15891005 PMID:16094769 PMID:16316325 More... NCBI chr11:13,492,054...13,496,181
Ensembl chr11:13,492,054...13,496,181
JBrowse link
G PTH1R parathyroid hormone 1 receptor affects expression ISO Calcium affects the expression of PTH1R mRNA CTD PMID:15913539 NCBI chr 3:46,877,689...46,903,799
Ensembl chr 3:46,877,721...46,903,799
JBrowse link
G PTK2B protein tyrosine kinase 2 beta multiple interactions EXP
ISO
Calcium affects the reaction [(N)-methanocarba-2MeSADP results in increased phosphorylation of PTK2B protein]
Calcium affects the phosphorylation of and affects the activity of PTK2B protein
CTD PMID:16236484 PMID:16877402 NCBI chr 8:27,311,478...27,459,391
Ensembl chr 8:27,311,482...27,459,391
JBrowse link
G PTPN12 protein tyrosine phosphatase non-receptor type 12 affects expression ISO Calcium affects the expression of PTPN12 mRNA CTD PMID:15913539 NCBI chr 7:77,537,190...77,640,069
Ensembl chr 7:77,537,295...77,640,069
JBrowse link
G PYGL glycogen phosphorylase L multiple interactions ISO [Phenylephrine co-treated with Calcium] results in increased activity of PYGL protein; Calcium deficiency inhibits the reaction [Calcimycin results in increased activity of PYGL protein]; Glucose inhibits the reaction [[Phenylephrine co-treated with Calcium] results in increased activity of PYGL protein] CTD PMID:747652 PMID:6430282 NCBI chr14:50,905,217...50,944,483
Ensembl chr14:50,857,891...50,944,483
JBrowse link
G RAB7A RAB7A, member RAS oncogene family affects expression ISO Calcium affects the expression of RAB7 mRNA CTD PMID:15913539 NCBI chr 3:128,726,183...128,814,798
Ensembl chr 3:128,693,669...128,825,942
JBrowse link
G RALGDS ral guanine nucleotide dissociation stimulator affects expression ISO Calcium affects the expression of RALGDS mRNA CTD PMID:15913539 NCBI chr 9:133,097,722...133,149,210
Ensembl chr 9:133,097,720...133,149,334
JBrowse link
G RAP1A RAP1A, member of RAS oncogene family multiple interactions EXP Calcium promotes the reaction [ibandronic acid results in decreased prenylation of RAP1A protein] CTD PMID:18190680 NCBI chr 1:111,542,009...111,716,691
Ensembl chr 1:111,542,218...111,716,691
JBrowse link
G RAPGEF3 Rap guanine nucleotide exchange factor 3 multiple interactions EXP RAPGEF3 protein promotes the reaction [Benzo(a)pyrene results in increased transport of Calcium] CTD PMID:22167199 NCBI chr12:47,734,363...47,758,880
Ensembl chr12:47,734,363...47,771,040
JBrowse link
G RBP1 retinol binding protein 1 affects expression ISO Calcium affects the expression of RBP1 mRNA CTD PMID:15913539 NCBI chr 3:139,517,438...139,539,742
Ensembl chr 3:139,517,434...139,539,829
JBrowse link
G REN renin decreases secretion
multiple interactions
ISO Calcium results in decreased secretion of REN protein
[[Calcium results in increased activity of MYLK protein] which results in increased phosphorylation of MYL9 protein] which results in decreased secretion of REN protein; ML 7 inhibits the reaction [Calcium results in decreased secretion of REN protein]
CTD PMID:9618396 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324
JBrowse link
G RGS4 regulator of G protein signaling 4 multiple interactions ISO RGS4 protein inhibits the reaction [PTAFR protein affects the localization of and affects the abundance of Calcium] CTD PMID:11297424 NCBI chr 1:163,068,871...163,076,802
Ensembl chr 1:163,068,775...163,076,802
JBrowse link
G RPS3A ribosomal protein S3A affects expression ISO Calcium affects the expression of RPS3A mRNA CTD PMID:15913539 NCBI chr 4:151,099,628...151,104,642
Ensembl chr 4:151,099,624...151,104,642
JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 multiple interactions ISO
EXP
Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of RPS6KB1 protein]
[Resveratrol results in increased abundance of Calcium] which results in decreased expression of RPS6KB1 protein modified form; dorsomorphin inhibits the reaction [[Resveratrol results in increased abundance of Calcium] which results in decreased expression of RPS6KB1 protein modified form]
CTD PMID:12935885 PMID:23680031 NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574
JBrowse link
G RPTOR regulatory associated protein of MTOR complex 1 multiple interactions EXP [Resveratrol results in increased abundance of Calcium] which results in increased activity of RPTOR protein modified form; dorsomorphin inhibits the reaction [[Resveratrol results in increased abundance of Calcium] which results in increased activity of RPTOR protein modified form] CTD PMID:23680031 NCBI chr17:80,544,838...80,966,368
Ensembl chr17:80,544,819...80,966,371
JBrowse link
G RRAGA Ras related GTP binding A affects expression ISO Calcium affects the expression of RRAGA mRNA CTD PMID:15913539 NCBI chr 9:19,049,427...19,051,025
Ensembl chr 9:19,049,427...19,051,025
JBrowse link
G RYR1 ryanodine receptor 1 multiple interactions
affects abundance
increases secretion
increases abundance
EXP
ISO
[Caffeine results in increased activity of RYR1 protein] which affects the localization of Calcium; [chlorocresol results in increased activity of RYR1 protein] which affects the localization of Calcium; [chlorocresol results in increased activity of RYR1 protein] which results in increased transport of Calcium; [Halothane results in increased activity of RYR1 protein] which affects the localization of Calcium; [RYR1 protein co-treated with 2,3,6,2',3',6'-hexachlorobiphenyl] affects the susceptibility to Calcium; Calcium affects the folding of [CALM1 protein binds to RYR1 protein modified form]; Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]; Dantrolene inhibits the reaction [[chlorocresol results in increased activity of RYR1 protein] which results in increased transport of Calcium]; RYR1 protein polymorphism affects the reaction [Caffeine results in increased secretion of Calcium]; RYR1 protein polymorphism affects the reaction [chlorocresol results in increased secretion of Calcium]
RYR1 protein polymorphism affects the abundance of Calcium
RYR1 protein mutant form results in increased secretion of Calcium
RYR1 gene mutant form results in increased abundance of Calcium
Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]; Calcium affects the reaction [CALM1 protein modified form binds to and affects the activity of RYR1 protein]
CTD PMID:15381065 PMID:15628869 PMID:16372898 PMID:17707769 PMID:18719443 More... NCBI chr19:38,433,691...38,587,564
Ensembl chr19:38,433,691...38,587,564
JBrowse link
G RYR2 ryanodine receptor 2 multiple interactions EXP
ISO
FKBP1A protein inhibits the reaction [Calcium results in increased activity of RYR2 protein]
Dantrolene inhibits the reaction [Caffeine promotes the reaction [RYR2 protein results in increased secretion of Calcium]]; HOMER1 protein alternative form inhibits the reaction [Caffeine promotes the reaction [RYR2 protein results in increased secretion of Calcium]]; HOMER1 protein alternative form inhibits the reaction [Cyclic ADP-Ribose promotes the reaction [RYR2 protein results in increased secretion of Calcium]]
CTD PMID:12887973 PMID:17872463 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988
JBrowse link
G S100A13 S100 calcium binding protein A13 multiple interactions EXP [Calcium co-treated with Copper] binds to and affects the folding of S100A13 protein; Calcium binds to and affects the folding of S100A13 protein CTD PMID:16766622 NCBI chr 1:153,618,799...153,634,361
Ensembl chr 1:153,618,787...153,631,360
JBrowse link
G S100A2 S100 calcium binding protein A2 affects binding
multiple interactions
EXP Calcium binds to S100A2 protein
[Zinc binds to S100A2 protein] inhibits the reaction [Calcium binds to S100A2 protein]
CTD PMID:17239974 NCBI chr 1:153,561,108...153,565,844
Ensembl chr 1:153,561,108...153,567,890
JBrowse link
G S100A6 S100 calcium binding protein A6 affects response to substance EXP S100A6 protein affects the susceptibility to Calcium CTD PMID:15068510 NCBI chr 1:153,534,599...153,536,049
Ensembl chr 1:153,534,599...153,536,244
JBrowse link
G S100A8 S100 calcium binding protein A8 multiple interactions
affects binding
EXP [Zinc co-treated with Calcium] binds to [S100A8 protein binds to S100A9 protein]
Calcium binds to [S100A8 protein binds to S100A9 protein]
CTD PMID:17050004 NCBI chr 1:153,390,032...153,422,583
Ensembl chr 1:153,390,032...153,391,073
JBrowse link
G S100A9 S100 calcium binding protein A9 affects binding
multiple interactions
EXP Calcium binds to [S100A8 protein binds to S100A9 protein]
[Zinc co-treated with Calcium] binds to [S100A8 protein binds to S100A9 protein]
CTD PMID:17050004 NCBI chr 1:153,357,854...153,361,023
Ensembl chr 1:153,357,854...153,361,023
JBrowse link
G S100G S100 calcium binding protein G affects expression ISO Calcium affects the expression of S100G mRNA CTD PMID:15913539 NCBI chr  X:16,649,787...16,654,674
Ensembl chr  X:16,650,158...16,654,670
JBrowse link
G SCGB1A1 secretoglobin family 1A member 1 increases expression EXP Calcium results in increased expression of SCGB1A1 mRNA; Calcium results in increased expression of SCGB1A1 protein CTD PMID:16237193 NCBI chr11:62,419,033...62,423,195
Ensembl chr11:62,405,103...62,423,195
JBrowse link
G SCT secretin increases abundance EXP SCT protein results in increased abundance of Calcium CTD PMID:1220513 NCBI chr11:626,095...627,692
Ensembl chr11:626,309...627,181
JBrowse link
G SEC61A1 SEC61 translocon subunit alpha 1 multiple interactions
increases transport
EXP [HSPA5 protein binds to SEC61A1 protein] which results in decreased transport of Calcium; [SEC61A1 protein results in increased transport of Calcium] which results in increased susceptibility to Thapsigargin; DNAJB11 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium]; DNAJC3 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium]