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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:alkaline earth metal atom
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Accession:CHEBI:22313 term browser browse the term
Synonyms:related_synonym: Erdalkalimetall;   Erdalkalimetalle;   alkaline-earth metal;   alkaline-earth metals;   metal alcalino-terreux;   metal alcalinoterreo;   metales alcalinoterreos;   metaux alcalino-terreux



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atorvastatin calcium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 increases expression
decreases expression
multiple interactions
ISO Atorvastatin results in increased expression of ABCA1 mRNA
Atorvastatin results in decreased expression of ABCA1 mRNA; Atorvastatin results in decreased expression of ABCA1 protein
[Rosiglitazone co-treated with Atorvastatin] results in increased expression of ABCA1 protein
CTD PMID:15183127 PMID:16386711 PMID:25278499 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO Atorvastatin inhibits the reaction [ABCB11 protein affects the import of Taurocholic Acid]; Atorvastatin inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Atorvastatin results in decreased activity of ABCB11 protein
CTD PMID:15901796 PMID:23956101 PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases expression
decreases activity
increases transport
ISO
EXP
ABCB1 alternative form affects the reaction [CYP3A4 polymorphism affects the susceptibility to Atorvastatin]; Atorvastatin analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]
Atorvastatin results in decreased expression of ABCB1A mRNA
Atorvastatin analog results in decreased activity of ABCB1 protein
ABCB1 protein results in increased transport of Atorvastatin; ABCB1 protein results in increased transport of Atorvastatin analog
CTD PMID:10751037 PMID:15616150 PMID:19802823 PMID:24502637 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression ISO Atorvastatin results in increased expression of ABCB4 mRNA; Atorvastatin results in increased expression of ABCB4 protein CTD PMID:15986414 PMID:25278499 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases activity
multiple interactions
increases expression
ISO
EXP
Atorvastatin analog results in decreased activity of ABCC2 protein
ABCC2 protein binds to and results in increased uptake of Atorvastatin analog; Atorvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Atorvastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]
Atorvastatin results in increased expression of ABCC2 mRNA
CTD PMID:15616150 PMID:23562342 PMID:25278499 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression ISO Atorvastatin results in increased expression of ABCC3 mRNA; Atorvastatin results in increased expression of ABCC3 protein CTD PMID:15986414 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO Atorvastatin results in increased expression of ABCG2 mRNA CTD PMID:25278499 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression ISO Atorvastatin results in increased expression of ABCG5 mRNA CTD PMID:25278499 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression ISO Atorvastatin results in increased expression of ABCG8 mRNA CTD PMID:25278499 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
JBrowse link
G Acacb acetyl-CoA carboxylase beta increases expression
multiple interactions
EXP Atorvastatin results in increased expression of ACACB mRNA
Mevalonic Acid inhibits the reaction [Atorvastatin results in increased expression of ACACB mRNA]
CTD PMID:12056585 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
JBrowse link
G Ace angiotensin I converting enzyme decreases expression EXP Atorvastatin results in decreased expression of ACE mRNA CTD PMID:23390189 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ace2 angiotensin converting enzyme 2 increases expression EXP Atorvastatin results in increased expression of ACE2 mRNA CTD PMID:23390189 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions EXP Atorvastatin inhibits the reaction [Fructose results in decreased expression of ACOX1 mRNA] CTD PMID:21122807 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of ACTA2 protein] CTD PMID:34939712 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Adam12 ADAM metallopeptidase domain 12 decreases expression ISO Atorvastatin results in decreased expression of ADAM12 protein CTD PMID:18360054 NCBI chr 1:188,686,984...189,014,206
Ensembl chr 1:188,686,989...189,020,667
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 decreases expression ISO Atorvastatin results in decreased expression of ADAM17 protein CTD PMID:18360054 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 multiple interactions ISO Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ADGRE1 protein] CTD PMID:37023836 NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression
increases expression
ISO Atorvastatin results in decreased expression of ADIPOQ protein
Atorvastatin results in increased expression of ADIPOQ protein
CTD PMID:19651449 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Agt angiotensinogen multiple interactions EXP Atorvastatin inhibits the reaction [AGT protein results in decreased expression of SOD1 protein]; Atorvastatin inhibits the reaction [AGT protein results in increased abundance of Malondialdehyde]; Atorvastatin inhibits the reaction [AGT protein results in increased activity of MAPK1 protein]; Atorvastatin inhibits the reaction [AGT protein results in increased activity of MAPK3 protein]; Atorvastatin inhibits the reaction [AGT protein results in increased expression of NOX1 protein] CTD PMID:19451411 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation
increases phosphorylation
ISO
EXP
Atorvastatin inhibits the reaction [Homocysteine results in decreased phosphorylation of AKT1 protein]
[Atorvastatin co-treated with Celecoxib] results in decreased phosphorylation of AKT1 protein; Atorvastatin results in decreased expression of and results in decreased phosphorylation of AKT1 protein
Atorvastatin results in decreased phosphorylation of AKT1 protein
Atorvastatin results in increased phosphorylation of AKT1 protein
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of AKT1 protein]; coenzyme Q10 inhibits the reaction [Atorvastatin results in decreased phosphorylation of AKT1 protein]
CTD PMID:18172863 PMID:19526287 PMID:20305681 PMID:27345130 PMID:27815113 More... NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Angpt2 angiopoietin 2 increases expression ISO Atorvastatin results in increased expression of ANGPT2 mRNA CTD PMID:16410222 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804
JBrowse link
G Apob apolipoprotein B multiple interactions
decreases secretion
decreases expression
ISO
EXP
Atorvastatin results in decreased expression of and results in decreased secretion of APOB protein
Atorvastatin inhibits the reaction [Fructose results in increased expression of APOB protein]
Atorvastatin results in decreased secretion of APOB protein
Atorvastatin results in decreased expression of APOB protein
CTD PMID:9512650 PMID:10357840 PMID:11728391 PMID:12065722 PMID:12172771 More... NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Apoe apolipoprotein E decreases expression
multiple interactions
ISO Atorvastatin results in decreased expression of APOE mRNA; Atorvastatin results in decreased expression of APOE protein
Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the activity of GPT protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of BAX protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of BCL2 protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of CASP3 protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of FTH1 protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of GPX4 protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of HMOX1 protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of NFE2L2 protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of RELA protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of TFRC protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of TRP53 protein]
[Bezafibrate co-treated with Enalapril co-treated with Dipyridamole co-treated with Atorvastatin co-treated with Valsartan] results in decreased expression of APOE protein
CTD PMID:16386711 PMID:19603250 PMID:32976958 PMID:37121058 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO Atorvastatin inhibits the reaction [APP protein results in decreased expression of SLC1A2 protein]; Atorvastatin inhibits the reaction [APP protein results in decreased expression of SLC1A3 protein] CTD PMID:20816828 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions EXP [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein] CTD PMID:34939712 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atg5 autophagy related 5 multiple interactions
increases response to substance
ISO ATG5 mutant form promotes the reaction [Atorvastatin results in increased cleavage of CASP3 protein]; ATG5 mutant form promotes the reaction [Atorvastatin results in increased cleavage of PARP1 protein]
ATG5 results in increased susceptibility to Atorvastatin
CTD PMID:20876807 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO Atorvastatin results in increased expression of BAK1 protein CTD PMID:19935899 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO Atorvastatin results in increased expression of BAX protein
Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of BAX protein]
CTD PMID:19935899 PMID:37121058 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO
EXP
Atorvastatin results in decreased expression of BCL2 mRNA; Atorvastatin results in decreased expression of BCL2 protein
Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of BCL2 protein]
[Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of BCL2 protein]
2-tert-butylhydroquinone inhibits the reaction [Atorvastatin results in decreased expression of BCL2 protein]; RHOA mutant form inhibits the reaction [Atorvastatin results in decreased expression of BCL2 protein]
CTD PMID:16470222 PMID:31423616 PMID:32259528 PMID:37121058 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Becn1 beclin 1 increases expression ISO Atorvastatin results in increased expression of BECN1 protein CTD PMID:20876807 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression ISO Atorvastatin results in increased expression of BGLAP mRNA CTD PMID:17252541 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions EXP Atorvastatin results in decreased expression of and results in increased cleavage of BID protein; Mevalonic Acid inhibits the reaction [Atorvastatin results in decreased expression of and results in increased cleavage of BID protein]; U 0126 inhibits the reaction [Atorvastatin results in decreased expression of and results in increased cleavage of BID protein] CTD PMID:18339080 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression EXP Atorvastatin results in decreased expression of BIRC5 mRNA; Atorvastatin results in decreased expression of BIRC5 protein CTD PMID:17372815 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bmp2 bone morphogenetic protein 2 increases expression
increases secretion
ISO Atorvastatin results in increased expression of BMP2 mRNA
Atorvastatin results in increased secretion of BMP2 protein
CTD PMID:16470222 PMID:17252541 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G C3 complement C3 multiple interactions EXP [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased activity of C3 protein modified form] CTD PMID:20946910 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Casp1 caspase 1 multiple interactions EXP [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CASP1 protein] CTD PMID:34939712 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 increases activity
decreases activity
multiple interactions
increases cleavage
ISO
EXP
Atorvastatin results in increased activity of CASP3 protein
Atorvastatin results in decreased activity of CASP3 protein
[Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased activity of CASP3 protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased activity of CASP3 protein]; U 0126 inhibits the reaction [Atorvastatin results in increased activity of CASP3 protein]
Atorvastatin results in increased cleavage of CASP3 protein
[PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the cleavage of CASP3 protein; ATG5 mutant form promotes the reaction [Atorvastatin results in increased cleavage of CASP3 protein]; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of CASP3 protein]; Atorvastatin inhibits the reaction [Homocysteine results in increased activity of CASP3 protein]
2-tert-butylhydroquinone inhibits the reaction [Atorvastatin results in increased cleavage of CASP3 protein]; [Atorvastatin co-treated with Celecoxib] results in increased cleavage of and results in increased activity of CASP3 protein; bafilomycin A1 promotes the reaction [Atorvastatin results in increased cleavage of CASP3 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin results in increased activity of CASP3 protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased activity of CASP3 protein]; RHOA protein inhibits the reaction [Atorvastatin results in increased activity of CASP3 protein]
CTD PMID:16470222 PMID:18172863 PMID:18339080 PMID:19429019 PMID:20305681 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions
increases activity
ISO
EXP
[Atorvastatin co-treated with Celecoxib] results in increased cleavage of CASP8 protein
[Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased activity of CASP8 protein]; [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased expression of CASP8 protein]
Atorvastatin results in increased activity of CASP8 protein
CTD PMID:15705602 PMID:18172863 PMID:20946910 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
ISO
EXP
[Atorvastatin co-treated with Celecoxib] results in increased cleavage of CASP9 protein
Mevalonic Acid inhibits the reaction [Atorvastatin results in increased activity of CASP9 protein]; U 0126 inhibits the reaction [Atorvastatin results in increased activity of CASP9 protein]
CTD PMID:15705602 PMID:16470222 PMID:18172863 PMID:18339080 PMID:29630879 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions
increases activity
EXP
ISO
Atorvastatin inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]
Atorvastatin results in increased activity of CAT protein
CTD PMID:17479860 PMID:25218292 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases expression
ISO
EXP
Atorvastatin inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Atorvastatin results in decreased expression of and results in decreased secretion of CCL2 protein; Mevalonic Acid inhibits the reaction [Atorvastatin inhibits the reaction [TNF results in increased expression of CCL2 mRNA]]; Mevalonic Acid inhibits the reaction [Atorvastatin results in decreased expression of CCL2 mRNA]
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CCL2 protein]; Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of CCL2 protein]
CTD PMID:12117737 PMID:25058445 PMID:34939712 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cd14 CD14 molecule decreases expression ISO Atorvastatin results in decreased expression of CD14 protein CTD PMID:18333374 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd36 CD36 molecule multiple interactions ISO
EXP
Atorvastatin inhibits the reaction [Rosiglitazone results in increased expression of CD36 mRNA]; Atorvastatin inhibits the reaction [Rosiglitazone results in increased expression of CD36 protein]
[Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of CD36 protein]
CTD PMID:15183127 PMID:16386711 PMID:32259528 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cd40 CD40 molecule decreases expression ISO Atorvastatin results in decreased expression of CD40 protein CTD PMID:16387846 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd40lg CD40 ligand decreases expression ISO Atorvastatin results in decreased expression of CD40LG protein CTD PMID:16368305 PMID:19171469 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Cd83 CD83 molecule decreases expression ISO Atorvastatin results in decreased expression of CD83 protein CTD PMID:16387846 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
JBrowse link
G Cd86 CD86 molecule decreases expression ISO Atorvastatin results in decreased expression of CD86 protein CTD PMID:16387846 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdc42 cell division cycle 42 multiple interactions ISO [Poly I-C co-treated with Atorvastatin] results in decreased expression of CDC42 mRNA CTD PMID:34696514 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Cdh1 cadherin 1 multiple interactions EXP [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of CDH1 protein] CTD PMID:34939712 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO [Atorvastatin co-treated with Celecoxib] results in increased expression of CDKN1A protein; CDKN1A protein mutant form inhibits the reaction [Atorvastatin results in increased cleavage of PARP1 protein]
Atorvastatin results in increased expression of CDKN1A protein
CTD PMID:18172863 PMID:20876807 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
increases expression
ISO [Atorvastatin co-treated with Celecoxib] results in increased expression of CDKN1B protein
Atorvastatin results in increased expression of CDKN1B protein
CTD PMID:16470222 PMID:18172863 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO Atorvastatin inhibits the reaction [Sodium Glutamate results in increased phosphorylation of CHUK protein] CTD PMID:19800637 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Clcn1 chloride voltage-gated channel 1 decreases expression EXP Atorvastatin results in decreased expression of CLCN1 protein CTD PMID:27377005 NCBI chr 4:71,171,949...71,201,483
Ensembl chr 4:71,172,547...71,199,984
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Atorvastatin results in increased expression of COL1A1 mRNA CTD PMID:17252541 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression
multiple interactions
EXP Atorvastatin results in increased expression of CPT1A mRNA
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Atorvastatin results in increased expression of CPT1A mRNA]
CTD PMID:19053045 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Crp C-reactive protein multiple interactions
decreases expression
ISO
EXP
[Atorvastatin co-treated with Amlodipine] results in decreased expression of CRP protein; Atorvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of CRP mRNA]; Atorvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of CRP protein]
Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of CRP protein]
Atorvastatin results in decreased expression of CRP protein
CTD PMID:16025360 PMID:16360360 PMID:17673219 PMID:18389332 PMID:21584495 More... NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cs citrate synthase increases expression
multiple interactions
EXP Atorvastatin results in increased expression of CS mRNA
Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of CS mRNA]
CTD PMID:21775390 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of CSF2 mRNA]; Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of CSF2 protein]; Atorvastatin inhibits the reaction [Particulate Matter results in increased expression of CSF2 mRNA]; Atorvastatin inhibits the reaction [Particulate Matter results in increased expression of CSF2 protein] CTD PMID:19482827 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression EXP Atorvastatin results in decreased expression of CXCL10 CTD PMID:15831368 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions EXP Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of CYBA mRNA] CTD PMID:25218292 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cycs cytochrome c, somatic multiple interactions
affects localization
EXP
ISO
[Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of CYCS protein]
Atorvastatin affects the localization of CYCS protein
2-tert-butylhydroquinone inhibits the reaction [Atorvastatin affects the localization of CYCS protein]
CTD PMID:31423616 PMID:32259528 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 affects expression EXP Atorvastatin affects the expression of CYP11A1 mRNA CTD PMID:29574565 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 increases expression EXP Atorvastatin results in increased expression of CYP17A1 mRNA CTD PMID:29574565 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression EXP Atorvastatin results in increased expression of CYP19A1 mRNA CTD PMID:29574565 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 increases expression EXP Atorvastatin results in increased expression of CYP21A2 mRNA CTD PMID:29574565 NCBI chr20:4,020,217...4,026,923
Ensembl chr20:4,023,767...4,026,923
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression
increases expression
ISO Atorvastatin results in decreased expression of CYP27A1 mRNA; Atorvastatin results in decreased expression of CYP27A1 protein
Atorvastatin results in increased expression of CYP27A1 mRNA
CTD PMID:16386711 PMID:25278499 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Atorvastatin results in increased expression of CYP2B6 mRNA
Atorvastatin results in increased expression of CYP2B10 mRNA; Atorvastatin results in increased expression of CYP2B10 protein
CTD PMID:15802384 PMID:15986414 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 increases expression ISO Atorvastatin results in increased expression of CYP39A1 mRNA CTD PMID:25278499 NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases expression
affects response to substance
increases metabolic processing
multiple interactions
affects metabolic processing
decreases activity
increases expression
EXP
ISO
Atorvastatin results in decreased expression of CYP3A4 mRNA; Atorvastatin results in decreased expression of CYP3A4 protein
CYP3A4 polymorphism affects the susceptibility to Atorvastatin
CYP3A4 protein results in increased metabolism of Atorvastatin
ABCB1 alternative form affects the reaction [CYP3A4 polymorphism affects the susceptibility to Atorvastatin]; Atorvastatin inhibits the reaction [CYP3A4 protein affects the metabolism of Midazolam]
CYP3A4 protein affects the metabolism of Atorvastatin
Atorvastatin results in decreased activity of CYP3A4 protein
Atorvastatin results in increased expression of CYP3A4 protein
Atorvastatin promotes the reaction [Berberine results in decreased activity of CYP3A4 protein]; Berberine promotes the reaction [Atorvastatin results in decreased activity of CYP3A4 protein]; Berberine promotes the reaction [Atorvastatin results in decreased expression of CYP3A4 mRNA]; Berberine promotes the reaction [Atorvastatin results in decreased expression of CYP3A4 protein]
CTD PMID:15963098 PMID:16011971 PMID:16029222 PMID:18528690 PMID:18846481 More... NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 multiple interactions EXP [Dietary Fats co-treated with Atorvastatin] results in increased expression of CYP3A23-3A1 protein CTD PMID:26616219 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases expression
multiple interactions
ISO
EXP
Atorvastatin results in increased expression of CYP7A1 mRNA
Atorvastatin inhibits the reaction [Dietary Fats results in decreased expression of CYP7A1 mRNA]
CTD PMID:25278499 PMID:32048413 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 decreases expression ISO Atorvastatin results in decreased expression of CYP7B1 mRNA CTD PMID:25278499 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
JBrowse link
G Dcx doublecortin increases expression EXP Atorvastatin results in increased expression of DCX protein CTD PMID:15255259 NCBI chr  X:107,430,767...107,573,612
Ensembl chr  X:107,430,767...107,507,476
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 increases expression
multiple interactions
increases activity
EXP Atorvastatin results in increased expression of DGAT1 mRNA
Mevalonic Acid inhibits the reaction [Atorvastatin results in increased activity of DGAT1 protein]
CTD PMID:12056585 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dscc1 DNA replication and sister chromatid cohesion 1 affects response to substance ISO DSCC1 protein affects the susceptibility to Atorvastatin CTD PMID:35926565 NCBI chr 7:86,482,588...86,498,212
Ensembl chr 7:86,482,588...86,498,212
JBrowse link
G Edn1 endothelin 1 decreases expression ISO Atorvastatin results in decreased expression of EDN1 protein CTD PMID:16360360 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A multiple interactions
decreases expression
EXP Atorvastatin promotes the reaction [Losartan results in decreased expression of EDNRA mRNA]; Losartan promotes the reaction [Atorvastatin results in decreased expression of EDNRA mRNA] CTD PMID:23091284 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO Atorvastatin inhibits the reaction [Phenylephrine results in increased expression of and results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:18360054 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases response to substance
ISO EIF2AK3 mutant form inhibits the reaction [Atorvastatin results in increased phosphorylation of EIF2S1 protein]
EIF2AK3 results in increased susceptibility to Atorvastatin
CTD PMID:20876807 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions
increases phosphorylation
ISO 4-phenylbutyric acid inhibits the reaction [Atorvastatin results in increased phosphorylation of EIF2S1 protein]; EIF2AK3 mutant form inhibits the reaction [Atorvastatin results in increased phosphorylation of EIF2S1 protein] CTD PMID:20876807 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Epb41 erythrocyte membrane protein band 4.1 multiple interactions EXP [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in decreased expression of EPB41 protein] CTD PMID:20946910 NCBI chr 5:144,110,010...144,264,037
Ensembl chr 5:144,111,906...144,237,821
JBrowse link
G F2 coagulation factor II, thrombin decreases activity ISO Atorvastatin results in decreased activity of F2 protein CTD PMID:16907931 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F5 coagulation factor V decreases activity ISO Atorvastatin results in decreased activity of F5 protein CTD PMID:16907931 NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317
JBrowse link
G Fadd Fas associated via death domain multiple interactions EXP [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased expression of FADD protein] CTD PMID:20946910 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fas Fas cell surface death receptor affects expression EXP Atorvastatin affects the expression of FAS mRNA; Atorvastatin affects the expression of FAS protein CTD PMID:17372815 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand multiple interactions
increases expression
EXP
ISO
[Atorvastatin co-treated with Acetylcysteine] inhibits the reaction [sodium arsenite results in increased expression of FASLG protein]
Atorvastatin results in increased expression of FASLG protein modified form
Atorvastatin inhibits the reaction [TNF protein results in decreased expression of and results in decreased secretion of FASLG protein modified form]
CTD PMID:15063428 PMID:20946910 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fasn fatty acid synthase increases expression
multiple interactions
ISO
EXP
Atorvastatin results in increased expression of FASN mRNA
[Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of FASN protein]; Atorvastatin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of FASN protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased expression of FASN mRNA]
CTD PMID:11728391 PMID:12056585 PMID:32259528 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbxo32 F-box protein 32 increases expression EXP Atorvastatin results in increased expression of FBXO32 mRNA CTD PMID:27377005 NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436
JBrowse link
G Fgf19 fibroblast growth factor 19 decreases expression ISO Atorvastatin results in decreased expression of FGF15 mRNA CTD PMID:25278499 NCBI chr 1:200,056,526...200,060,980
Ensembl chr 1:200,056,644...200,060,287
JBrowse link
G Foxo1 forkhead box O1 decreases phosphorylation ISO Atorvastatin results in decreased phosphorylation of FOXO1 protein CTD PMID:33034787 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of FTH1 protein] CTD PMID:32976958 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO [Atorvastatin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA CTD PMID:24204015 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
JBrowse link
G Gck glucokinase decreases expression
multiple interactions
ISO
EXP
Atorvastatin results in decreased expression of GCK protein
NR1I2 protein promotes the reaction [Atorvastatin results in decreased expression of GCK protein]
CTD PMID:26616219 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions EXP Atorvastatin promotes the reaction [dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of GJA1 protein]] CTD PMID:34939712 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gng3 G protein subunit gamma 3 multiple interactions
affects localization
EXP [Isoproterenol co-treated with Atorvastatin] affects the localization of GNG3 protein
Atorvastatin affects the localization of GNG3 protein
CTD PMID:19136528 NCBI chr 1:205,731,837...205,733,603
Ensembl chr 1:205,731,837...205,733,603
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions EXP Atorvastatin inhibits the reaction [Streptozocin results in increased secretion of GOT1 protein] CTD PMID:30657622 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial multiple interactions EXP Atorvastatin inhibits the reaction [Fructose results in increased expression of GPAM mRNA] CTD PMID:19053045 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO
EXP
[Atorvastatin co-treated with Ciprofloxacin] results in increased expression of GPT protein; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the activity of GPT protein]; Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of GPT protein]; Buthionine Sulfoximine promotes the reaction [[Atorvastatin co-treated with Ciprofloxacin] results in increased expression of GPT protein]
[Atorvastatin co-treated with triptolide] results in increased expression of GPT protein; [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of GPT protein]; Atorvastatin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of GPT protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased secretion of GPT protein]
CTD PMID:29679711 PMID:30657622 PMID:32259528 PMID:32976958 PMID:33600922 More... NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions ISO Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of GPX4 protein] CTD PMID:32976958 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Hbegf heparin-binding EGF-like growth factor decreases expression ISO Atorvastatin results in decreased expression of HBEGF protein CTD PMID:18360054 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
affects binding
increases expression
increases activity
ISO
EXP
Atorvastatin results in increased expression of and results in increased activity of HMGCR protein
Atorvastatin binds to HMGCR protein
Atorvastatin inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in decreased expression of HMGCR mRNA]; Atorvastatin inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in increased activity of HMGCR protein]; Atorvastatin inhibits the reaction [Dietary Fats results in increased expression of HMGCR mRNA]; Atorvastatin results in increased expression of and results in increased activity of HMGCR protein; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased activity of HMGCR protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased expression of HMGCR mRNA]
CTD PMID:9512650 PMID:10357840 PMID:12056585 PMID:12065722 PMID:12612140 More... NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO
EXP
Atorvastatin results in increased expression of HMOX1 mRNA
Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of HMOX1 protein]
[Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; Atorvastatin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]
CTD PMID:16410222 PMID:32259528 PMID:32976958 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha multiple interactions EXP Atorvastatin inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in decreased expression of HNF4A mRNA] CTD PMID:30273964 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression
ISO
EXP
Atorvastatin inhibits the reaction [TNF results in increased expression of ICAM1]
Atorvastatin results in increased expression of ICAM1 protein
Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of ICAM1 protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]
CTD PMID:12615677 PMID:17589825 PMID:19171469 PMID:25058445 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO Atorvastatin inhibits the reaction [Sodium Glutamate results in increased phosphorylation of IKBKB protein] CTD PMID:19800637 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Il12a interleukin 12A decreases expression ISO Atorvastatin results in decreased expression of IL12A mRNA CTD PMID:12492458 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il18 interleukin 18 multiple interactions ISO Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL18 protein] CTD PMID:37023836 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of IL1B mRNA]; Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of IL1B protein]; Atorvastatin inhibits the reaction [Particulate Matter results in increased expression of IL1B mRNA]; Atorvastatin inhibits the reaction [Particulate Matter results in increased expression of IL1B protein]
Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL1B mRNA]; Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL1B protein]
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of IL1B protein]; Atorvastatin inhibits the reaction [[Dietary Fats co-treated with Ergocalciferols] results in increased expression of IL1B protein]; Atorvastatin inhibits the reaction [Dietary Fats results in increased expression of IL1B protein]; Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of IL1B protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]
CTD PMID:17589825 PMID:19482827 PMID:25058445 PMID:32048413 PMID:34939712 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha affects expression ISO Atorvastatin affects the expression of IL2RA protein CTD PMID:16387846 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
decreases secretion
ISO
EXP
Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of IL6 mRNA]; Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of IL6 protein]; Atorvastatin inhibits the reaction [Particulate Matter results in increased expression of IL6 mRNA]; Atorvastatin inhibits the reaction [Particulate Matter results in increased expression of IL6 protein]; Atorvastatin inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Atorvastatin promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Atorvastatin results in decreased expression of and results in decreased secretion of IL6 protein; Mevalonic Acid inhibits the reaction [Atorvastatin inhibits the reaction [TNF results in increased expression of IL6 mRNA]]; Mevalonic Acid inhibits the reaction [Atorvastatin results in decreased expression of IL6 mRNA]
Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 protein]; Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of IL6 mRNA]; Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of IL6 protein]
Atorvastatin results in decreased expression of IL6 mRNA; Atorvastatin results in decreased expression of IL6 protein
Atorvastatin inhibits the reaction [[Dietary Fats co-treated with Ergocalciferols] results in increased expression of IL6 protein]; Atorvastatin inhibits the reaction [Dietary Fats results in increased expression of IL6 protein]; Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of IL6 protein]
Atorvastatin results in decreased secretion of IL6 protein
CTD PMID:12117737 PMID:16387846 PMID:17521631 PMID:19171469 PMID:19482827 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins1 insulin 1 multiple interactions ISO
EXP
Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of INS1 protein]
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of INS1 protein]
CTD PMID:19800637 PMID:34939712 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Ins2 insulin 2 increases expression ISO Atorvastatin results in increased expression of INS protein CTD PMID:19651449 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 multiple interactions ISO [Atorvastatin co-treated with Enalapril] results in decreased expression of IRAK1 mRNA; [Atorvastatin co-treated with Telmisartan] results in decreased expression of IRAK1 mRNA CTD PMID:20524934 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521
JBrowse link
G Itga2 integrin subunit alpha 2 multiple interactions ISO
EXP
Atorvastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]; geranylgeraniol inhibits the reaction [Atorvastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]] CTD PMID:12500026 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481
JBrowse link
G Itgal integrin subunit alpha L multiple interactions ISO Atorvastatin inhibits the reaction [TNF results in increased expression of ITGAL] CTD PMID:12615677 NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732
JBrowse link
G Itgam integrin subunit alpha M decreases expression ISO Atorvastatin results in decreased expression of ITGAM protein CTD PMID:18333374 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itgax integrin subunit alpha X decreases expression ISO Atorvastatin results in decreased expression of ITGAX protein CTD PMID:18333374 NCBI chr 1:182,709,653...182,740,709
Ensembl chr 1:182,719,609...182,740,698
JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions
increases expression
ISO
EXP
Atorvastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]; geranylgeraniol inhibits the reaction [Atorvastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased expression of ITGB1 mRNA] CTD PMID:12500026 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itgb2 integrin subunit beta 2 multiple interactions ISO Atorvastatin inhibits the reaction [TNF results in increased expression of ITGB2] CTD PMID:12615677 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Atorvastatin co-treated with Celecoxib] results in increased expression of JUN protein; Atorvastatin results in increased phosphorylation of and results in increased activity of JUN protein; Celecoxib promotes the reaction [Atorvastatin results in increased phosphorylation of and results in increased activity of JUN protein] CTD PMID:18172863 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity
multiple interactions
EXP Atorvastatin results in decreased activity of KCNH2 protein
Berberine promotes the reaction [Atorvastatin results in decreased activity of KCNH2 protein]
CTD PMID:30086269 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Khk ketohexokinase multiple interactions EXP Atorvastatin inhibits the reaction [Fructose results in increased expression of KHK protein] CTD PMID:21122807 NCBI chr 6:25,445,298...25,455,834
Ensembl chr 6:25,445,300...25,455,717
JBrowse link
G Kif6 kinesin family member 6 increases response to substance ISO KIF6 polymorphism results in increased susceptibility to Atorvastatin CTD PMID:21943003 NCBI chr 9:11,076,203...11,373,205
Ensembl chr 9:11,072,824...11,373,006
JBrowse link
G Kpna2 karyopherin subunit alpha 2 affects localization
multiple interactions
ISO Atorvastatin affects the localization of KPNA2 protein
[Ivermectin co-treated with Atorvastatin] affects the localization of KPNA2 protein
CTD PMID:34696514 NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150
JBrowse link
G Kpna7 karyopherin subunit alpha 7 multiple interactions ISO Atorvastatin inhibits the reaction [Poly I-C results in increased expression of KPNA7 mRNA] CTD PMID:34696514 NCBI chr12:9,576,378...9,635,247
Ensembl chr12:9,576,378...9,612,833
JBrowse link
G Lcat lecithin cholesterol acyltransferase multiple interactions EXP Atorvastatin inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in increased activity of LCAT protein] CTD PMID:30273964 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lcn2 lipocalin 2 multiple interactions ISO
EXP
[Buthionine Sulfoximine co-treated with Atorvastatin co-treated with Ciprofloxacin] results in increased expression of LCN2 mRNA
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of LCN2 protein]; Atorvastatin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of LCN2 protein]
CTD PMID:29679711 PMID:32259528 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Ldlr low density lipoprotein receptor increases activity
multiple interactions
increases expression
ISO
EXP
Atorvastatin results in increased activity of LDLR protein
Atorvastatin inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in decreased expression of LDLR mRNA]; Atorvastatin inhibits the reaction [Dietary Fats results in decreased expression of LDLR mRNA]
Atorvastatin results in increased expression of LDLR mRNA
CTD PMID:10357840 PMID:11728391 PMID:12612140 PMID:24502637 PMID:30273964 More... NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lep leptin multiple interactions EXP Atorvastatin affects the reaction [Fructose results in increased expression of LEP protein] CTD PMID:21122807 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lpl lipoprotein lipase multiple interactions EXP Atorvastatin inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in increased activity of LPL protein] CTD PMID:30273964 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions EXP [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased lipidation of MAP1LC3B protein] CTD PMID:34939712 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
decreases phosphorylation
ISO
EXP
geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin results in decreased phosphorylation of MAPK1 protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in decreased phosphorylation of MAPK1 protein]; RHOA mutant form inhibits the reaction [Atorvastatin results in decreased phosphorylation of MAPK1 protein]
Atorvastatin inhibits the reaction [AGT protein results in increased activity of MAPK1 protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Atorvastatin results in increased phosphorylation of MAPK1 protein]
Atorvastatin inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein]
CTD PMID:16470222 PMID:18339080 PMID:18360054 PMID:19451411 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO
EXP
Atorvastatin inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]
Atorvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK14 protein]
CTD PMID:17589825 PMID:19767766 PMID:20018284 PMID:20305681 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation
increases phosphorylation
ISO
EXP
geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin results in decreased phosphorylation of MAPK3 protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in decreased phosphorylation of MAPK3 protein]; RHOA mutant form inhibits the reaction [Atorvastatin results in decreased phosphorylation of MAPK3 protein]
Atorvastatin inhibits the reaction [AGT protein results in increased activity of MAPK3 protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Atorvastatin results in increased phosphorylation of MAPK3 protein]
Atorvastatin inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD PMID:16470222 PMID:18339080 PMID:18360054 PMID:19451411 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mb myoglobin increases expression
multiple interactions
EXP
ISO
Atorvastatin results in increased expression of MB protein
[Buthionine Sulfoximine co-treated with Atorvastatin co-treated with Ciprofloxacin] results in increased secretion of MB protein
CTD PMID:27815113 PMID:29679711 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO Atorvastatin results in decreased expression of MCL1 protein CTD PMID:16470222 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO Atorvastatin results in increased expression of MDM2 protein CTD PMID:29630879 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mef2d myocyte enhancer factor 2D increases expression EXP Atorvastatin results in increased expression of MEF2D mRNA CTD PMID:27377005 NCBI chr 2:173,606,054...173,635,620
Ensembl chr 2:173,606,490...173,634,457
JBrowse link
G Mfn2 mitofusin 2 multiple interactions EXP Atorvastatin inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of MFN2 protein] CTD PMID:24721408 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mir133b microRNA 133b multiple interactions ISO [Buthionine Sulfoximine co-treated with Atorvastatin co-treated with Ciprofloxacin] results in increased expression of MIR133B mRNA CTD PMID:29679711 NCBI chr 9:23,098,134...23,098,217
Ensembl chr 9:23,098,134...23,098,217
JBrowse link
G Mir145 microRNA 145 increases expression ISO Atorvastatin results in increased expression of MIR145 mRNA CTD PMID:29630879 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
JBrowse link
G Mir146a microRNA 146a multiple interactions ISO [Atorvastatin co-treated with Enalapril] results in decreased expression of MIR146A; [Atorvastatin co-treated with Telmisartan] results in decreased expression of MIR146A CTD PMID:20524934 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
JBrowse link
G Mir146b microRNA 146b multiple interactions ISO [Atorvastatin co-treated with Enalapril] results in decreased expression of MIR146B; [Atorvastatin co-treated with Telmisartan] results in decreased expression of MIR146B CTD PMID:20524934 NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525
JBrowse link
G Mir206 microRNA 206 multiple interactions ISO [Buthionine Sulfoximine co-treated with Atorvastatin co-treated with Ciprofloxacin] results in increased expression of MIR206 mRNA CTD PMID:29679711 NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:23,094,249...23,094,332
JBrowse link
G Mir221 microRNA 221 decreases expression ISO Atorvastatin results in decreased expression of MIR221 CTD PMID:25517390 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573
JBrowse link
G Mir222 microRNA 222 decreases expression ISO Atorvastatin results in decreased expression of MIR222 CTD PMID:25517390 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006
JBrowse link
G Mlxipl MLX interacting protein-like multiple interactions EXP Atorvastatin inhibits the reaction [Fructose affects the localization of and results in increased activity of MLXIPL protein]; Atorvastatin inhibits the reaction [Fructose results in increased expression of MLXIPL protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Atorvastatin inhibits the reaction [Fructose results in increased activity of MLXIPL protein]] CTD PMID:19053045 PMID:21122807 NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression
increases activity
ISO
EXP
Atorvastatin results in decreased expression of MMP2 protein
Atorvastatin results in increased activity of MMP2 protein
CTD PMID:18360054 PMID:23831763 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases activity
ISO
EXP
Atorvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Atorvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Sildenafil Citrate promotes the reaction [Atorvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]]
Atorvastatin results in increased activity of MMP9 protein
CTD PMID:15728660 PMID:23831763 PMID:26614570 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Atorvastatin inhibits the reaction [Paraquat results in increased activity of MPO protein] CTD PMID:27883937 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Msr1 macrophage scavenger receptor 1 multiple interactions ISO [Rosiglitazone co-treated with Atorvastatin] results in increased expression of MSR1 mRNA CTD PMID:15183127 NCBI chr16:52,717,775...52,803,602
Ensembl chr16:52,717,732...52,799,676
JBrowse link
G Mstn myostatin increases expression ISO Atorvastatin results in increased expression of MSTN protein CTD PMID:33034787 NCBI chr 9:48,452,533...48,458,933
Ensembl chr 9:48,452,533...48,458,933
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I affects expression
multiple interactions
EXP Atorvastatin affects the expression of COX1 mRNA
Quercetin inhibits the reaction [Atorvastatin affects the expression of COX1 mRNA]
CTD PMID:21775390 NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt1-ps2 metallothionein 1, pseudogene 2 multiple interactions EXP Atorvastatin inhibits the reaction [Fructose results in increased expression of MT1-PS2 mRNA] CTD PMID:21122807
G Mt2A metallothionein 2A multiple interactions EXP Atorvastatin inhibits the reaction [Fructose results in increased expression of MT2A mRNA] CTD PMID:21122807 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions EXP [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of and results in increased phosphorylation of MTOR protein] CTD PMID:34939712 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Mttp microsomal triglyceride transfer protein increases expression
multiple interactions
decreases expression
EXP
ISO
Atorvastatin results in increased expression of MTTP mRNA
Mevalonic Acid inhibits the reaction [Atorvastatin results in increased expression of MTTP mRNA]
Atorvastatin results in decreased expression of MTTP mRNA
CTD PMID:10357840 PMID:12056585 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO Atorvastatin results in decreased expression of MYC mRNA CTD PMID:29630879 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions EXP Atorvastatin inhibits the reaction [[Dietary Fats co-treated with Ergocalciferols] results in increased expression of MYD88 mRNA]; Atorvastatin inhibits the reaction [[Dietary Fats co-treated with Ergocalciferols] results in increased expression of MYD88 protein] CTD PMID:38213245 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Myh2 myosin heavy chain 2 multiple interactions
affects expression
ISO [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of MYH2 protein
Atorvastatin affects the expression of MYH2 protein
CTD PMID:30511338 NCBI chr10:51,856,738...51,883,236
Ensembl chr10:51,856,738...51,883,236
JBrowse link
G Nfe2l1 NFE2 like bZIP transcription factor 1 increases expression ISO Atorvastatin results in increased expression of NFE2L1 mRNA CTD PMID:30511338 NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
decreases expression
increases expression
ISO
EXP
[PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of NFE2L2 mRNA; Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of NFE2L2 protein]
Atorvastatin results in decreased expression of NFE2L2 protein
2-tert-butylhydroquinone inhibits the reaction [Atorvastatin results in decreased expression of NFE2L2 protein]
[Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of NFE2L2 protein]; Atorvastatin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of NFE2L2 protein]
Atorvastatin results in increased expression of NFE2L2 mRNA
CTD PMID:30511338 PMID:31423616 PMID:32259528 PMID:32976958 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO [Ivermectin co-treated with Atorvastatin] inhibits the reaction [Poly I-C results in increased expression of NFKB1 mRNA]; Atorvastatin inhibits the reaction [Poly I-C results in increased expression of NFKB1 mRNA]
Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of NFKB1 mRNA]
CTD PMID:34696514 PMID:37023836 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP
ISO
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of NLRP3 protein]
Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of NLRP3 mRNA]
CTD PMID:34939712 PMID:37023836 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nnmt nicotinamide N-methyltransferase increases expression ISO Atorvastatin results in increased expression of NNMT protein CTD PMID:33073877 NCBI chr 8:48,928,663...48,947,734
Ensembl chr 8:48,933,598...48,946,655
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
EXP Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of NOS2 mRNA]; Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of NOS2 protein]
Atorvastatin results in decreased expression of NOS2 mRNA; Atorvastatin results in decreased expression of NOS2 protein
CTD PMID:15166393 PMID:25058445 PMID:25218292 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
increases expression
affects response to substance
ISO
EXP
Atorvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of NOS3 mRNA]; Atorvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of NOS3 protein]; Melatonin promotes the reaction [Atorvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of NOS3 protein]]
Atorvastatin results in increased expression of NOS3 mRNA; Atorvastatin results in increased expression of NOS3 protein
[Dexamethasone co-treated with Atorvastatin] results in increased expression of NOS3 mRNA; [Losartan co-treated with Atorvastatin] results in increased expression of NOS3 mRNA; Atorvastatin inhibits the reaction [Dexamethasone results in decreased expression of NOS3 mRNA]; Atorvastatin inhibits the reaction [sodium arsenite results in decreased expression of and results in decreased phosphorylation of NOS3 protein]; Atorvastatin inhibits the reaction [sodium arsenite results in decreased expression of NOS3 mRNA]; Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of NOS3 protein]; Atorvastatin inhibits the reaction [Streptozocin results in decreased expression of NOS3 protein]
Atorvastatin inhibits the reaction [Homocysteine results in decreased expression of NOS3 mRNA]; Atorvastatin inhibits the reaction [Homocysteine results in decreased phosphorylation of NOS3 protein]
NOS3 promoter SNP affects the susceptibility to Atorvastatin
CTD PMID:12490971 PMID:15166393 PMID:16410222 PMID:16962929 PMID:17042910 More... NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions EXP Atorvastatin inhibits the reaction [AGT protein results in increased expression of NOX1 protein] CTD PMID:19451411 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236
JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions EXP
ISO
Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of NOX4 mRNA]
Atorvastatin inhibits the reaction [Homocysteine results in increased expression of NOX4 mRNA]
CTD PMID:20018284 PMID:25218292 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Nppa natriuretic peptide A multiple interactions EXP Atorvastatin inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA] CTD PMID:19136528 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nppb natriuretic peptide B decreases expression ISO Atorvastatin results in decreased expression of NPPB protein CTD PMID:18360054 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression ISO Atorvastatin results in decreased expression of NR0B2 mRNA CTD PMID:25278499 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases expression
ISO
EXP
[Atorvastatin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA; [Atorvastatin co-treated with NR1I2 protein] results in increased expression of SGK2 mRNA; NR1I2 protein promotes the reaction [Atorvastatin results in decreased expression of GCK protein]; NR1I2 protein promotes the reaction [Atorvastatin results in decreased expression of SLC2A2 protein]
Atorvastatin promotes the reaction [Dietary Fats results in increased expression of NR1I2 protein]
Atorvastatin binds to and results in increased activity of NR1I2 protein
Atorvastatin results in increased expression of NR1I2 protein
CTD PMID:15986414 PMID:24204015 PMID:26616219 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO
EXP
Atorvastatin results in increased activity of NR1I3 protein CTD PMID:15802384 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Nrf1 nuclear respiratory factor 1 multiple interactions
affects expression
increases expression
EXP Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of NRF1 mRNA]; Quercetin inhibits the reaction [Atorvastatin affects the expression of NRF1 mRNA] CTD PMID:21775390 NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO 2-tert-butylhydroquinone inhibits the reaction [Atorvastatin results in increased cleavage of PARP1 protein]; [Atorvastatin co-treated with Celecoxib] results in increased cleavage of PARP1 protein; bafilomycin A1 promotes the reaction [Atorvastatin results in increased cleavage of PARP1 protein]; CDKN1A protein mutant form inhibits the reaction [Atorvastatin results in increased cleavage of PARP1 protein]
ATG5 mutant form promotes the reaction [Atorvastatin results in increased cleavage of PARP1 protein]
CTD PMID:16470222 PMID:18172863 PMID:20876807 PMID:31423616 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pcyt1a phosphate cytidylyltransferase 1A, choline increases activity EXP Atorvastatin results in increased activity of PCYT1A protein CTD PMID:12056585 NCBI chr11:68,313,860...68,357,828
Ensembl chr11:68,313,882...68,357,357
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 multiple interactions EXP Atorvastatin inhibits the reaction [TNF protein results in decreased expression of PDK4 protein]; Mevalonic Acid inhibits the reaction [Atorvastatin inhibits the reaction [TNF protein results in decreased expression of PDK4 protein]] CTD PMID:22343369 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 multiple interactions ISO [Atorvastatin co-treated with Celecoxib] results in decreased phosphorylation of and results in decreased expression of PDPK1 protein CTD PMID:18172863 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha decreases expression ISO Atorvastatin results in decreased expression of PIK3CA mRNA CTD PMID:29630879 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pklr pyruvate kinase L/R multiple interactions EXP Atorvastatin inhibits the reaction [Fructose results in increased expression of PKLR mRNA] CTD PMID:19053045 PMID:21122807 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
JBrowse link
G Pkm pyruvate kinase M1/2 increases expression EXP Atorvastatin results in increased expression of PKM mRNA CTD PMID:27377005 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
JBrowse link
G Plau plasminogen activator, urokinase decreases expression ISO Atorvastatin results in decreased expression of PLAU protein CTD PMID:16410222 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Plin2 perilipin 2 multiple interactions EXP [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of PLIN2 protein] CTD PMID:34939712 NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Pomc proopiomelanocortin increases expression EXP Atorvastatin results in increased expression of POMC protein CTD PMID:29574565 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Pon1 paraoxonase 1 increases activity
multiple interactions
increases expression
ISO
EXP
Atorvastatin results in increased activity of PON1 protein
Atorvastatin inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in decreased secretion of PON1 protein]
PON1 gene polymorphism affects the reaction [Atorvastatin results in increased abundance of Cholesterol, HDL]; PON1 gene SNP affects the reaction [Atorvastatin results in increased abundance of Cholesterol, HDL]; PON1 protein affects the reaction [Atorvastatin results in increased abundance of Cholesterol, HDL]
Atorvastatin results in increased expression of PON1 mRNA
CTD PMID:15324535 PMID:15690306 PMID:15969877 PMID:16238680 PMID:30273964 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Pon2 paraoxonase 2 increases activity
increases expression
ISO Atorvastatin results in increased activity of PON2 protein
Atorvastatin results in increased expression of PON2 mRNA
CTD PMID:14592851 NCBI chr 4:33,389,702...33,425,186
Ensembl chr 4:33,389,714...33,425,248
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression
multiple interactions
ISO
EXP
Atorvastatin results in decreased expression of PPARA mRNA
Atorvastatin promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of PPARA protein]; Atorvastatin inhibits the reaction [Fructose results in increased expression of PPARA protein]
CTD PMID:12065722 PMID:18812576 PMID:21554872 PMID:32259528 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha decreases expression
affects expression
multiple interactions
increases expression
EXP
ISO
Atorvastatin results in decreased expression of PPARGC1A mRNA
Atorvastatin affects the expression of PPARGC1A mRNA
Atorvastatin results in decreased expression of PPARGC1A protein
[PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of PPARGC1A mRNA
Atorvastatin results in increased expression of PPARGC1A mRNA
[Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of PPARGC1A protein]; Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of PPARGC1A mRNA]; Atorvastatin inhibits the reaction [TNF protein results in decreased expression of PPARGC1A protein]; Farnesol inhibits the reaction [Atorvastatin inhibits the reaction [TNF protein results in decreased expression of PPARGC1A protein]]
CTD PMID:21775390 PMID:22343369 PMID:30511338 PMID:32259528 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ppargc1b PPARG coactivator 1 beta affects expression
decreases expression
affects response to substance
multiple interactions
EXP
ISO
Atorvastatin affects the expression of PPARGC1B mRNA
Atorvastatin results in decreased expression of PPARGC1B mRNA
PPARGC1B protein affects the susceptibility to Atorvastatin
Atorvastatin affects the expression of PPARGC1B protein
[PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the cleavage of CASP3 protein; [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of MYH2 protein; [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of NFE2L2 mRNA; [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of PPARGC1A mRNA; [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of PPARGC1B mRNA; [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of SOD2 protein; [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of TFAM mRNA; [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of TOMM20 protein
Quercetin inhibits the reaction [Atorvastatin affects the expression of PPARGC1B mRNA]
CTD PMID:21775390 PMID:30511338 NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha increases expression EXP Atorvastatin results in increased expression of PPP3CA mRNA CTD PMID:27377005 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases activity ISO Atorvastatin results in increased activity of PRKAA1 protein CTD PMID:33073877 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions EXP Atorvastatin results in increased phosphorylation of and results in increased activity of PRKACA protein; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Atorvastatin results in increased phosphorylation of and results in increased activity of PRKACA protein] CTD PMID:19053045 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Prkca protein kinase C, alpha multiple interactions EXP [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of and results in increased phosphorylation of PRKCA protein] CTD PMID:32259528 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkcq protein kinase C, theta increases expression EXP Atorvastatin results in increased expression of PRKCQ mRNA; Atorvastatin results in increased expression of PRKCQ protein CTD PMID:27377005 NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704
JBrowse link
G Prkcz protein kinase C, zeta multiple interactions EXP [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of PRKCZ protein] CTD PMID:32259528 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
JBrowse link
G Pten phosphatase and tensin homolog increases expression EXP Atorvastatin results in increased expression of PTEN protein CTD PMID:15837263 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
EXP [Atorvastatin co-treated with Pioglitazone] results in increased expression of PTGS2 protein; [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of PTGS2 protein]
Atorvastatin results in increased expression of PTGS2 protein
CTD PMID:16908763 PMID:34939712 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO
EXP
[Poly I-C co-treated with Atorvastatin] results in decreased expression of RAC1 mRNA; Atorvastatin inhibits the reaction [Glucose results in increased localization of RAC1 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin inhibits the reaction [Glucose results in increased localization of RAC1 protein]]
Atorvastatin inhibits the reaction [Streptozocin results in increased activity of RAC1 protein]
Atorvastatin inhibits the reaction [Streptozocin results in increased activity of and results in increased localization of RAC1 protein]
CTD PMID:17279352 PMID:17589825 PMID:34696514 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO [Atorvastatin co-treated with Celecoxib] results in decreased expression of RB1 protein modified form; [Atorvastatin co-treated with Celecoxib] results in increased expression of RB1 protein CTD PMID:18172863 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP
ISO
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of RELA protein]; Atorvastatin inhibits the reaction [[Dietary Fats co-treated with Ergocalciferols] results in increased expression of RELA mRNA]; Atorvastatin inhibits the reaction [[Dietary Fats co-treated with Ergocalciferols] results in increased expression of RELA protein]; Atorvastatin inhibits the reaction [Nitroglycerin results in increased localization of RELA protein]
Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of RELA protein]
CTD PMID:19733216 PMID:34939712 PMID:37121058 PMID:38213245 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rhoa ras homolog family member A increases expression
decreases activity
multiple interactions
decreases localization
ISO
EXP
Atorvastatin results in increased expression of RHOA protein
Atorvastatin results in decreased activity of RHOA protein
Atorvastatin inhibits the reaction [Streptozocin results in increased activity of RHOA protein]
[Poly I-C co-treated with Atorvastatin co-treated with Ivermectin] results in increased expression of RHOA mRNA; [Poly I-C co-treated with Atorvastatin] results in increased expression of RHOA mRNA; Atorvastatin results in increased localization of and results in decreased prenylation of RHOA protein; Celecoxib promotes the reaction [Atorvastatin results in decreased localization of RHOA protein]; Celecoxib promotes the reaction [Atorvastatin results in increased expression of RHOA protein]; geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin results in decreased activity of RHOA protein]; geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin results in increased localization of RHOA protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in decreased activity of RHOA protein]; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased localization of RHOA protein]; RHOA mutant form inhibits the reaction [Atorvastatin results in decreased expression of BCL2 protein]; RHOA mutant form inhibits the reaction [Atorvastatin results in decreased phosphorylation of MAPK1 protein]; RHOA mutant form inhibits the reaction [Atorvastatin results in decreased phosphorylation of MAPK3 protein]; RHOA protein inhibits the reaction [Atorvastatin results in increased activity of CASP3 protein]
CTD PMID:16470222 PMID:17589825 PMID:18172863 PMID:34696514 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rhob ras homolog family member B increases localization
increases expression
multiple interactions
ISO Atorvastatin results in increased localization of RHOB protein
Atorvastatin results in increased expression of RHOB protein
[Atorvastatin co-treated with Celecoxib] results in increased localization of RHOB protein; Celecoxib promotes the reaction [Atorvastatin results in increased expression of RHOB protein]
CTD PMID:18172863 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
JBrowse link
G Rhoc ras homolog family member C decreases localization
multiple interactions
increases expression
ISO Atorvastatin results in decreased localization of RHOC protein
Celecoxib promotes the reaction [Atorvastatin results in decreased localization of RHOC protein]; Celecoxib promotes the reaction [Atorvastatin results in increased expression of RHOC protein]
CTD PMID:18172863 NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306
JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions ISO [Rosiglitazone co-treated with Atorvastatin] results in increased expression of SCARB1 protein CTD PMID:15183127 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions EXP Atorvastatin inhibits the reaction [Fructose results in increased expression of SCD1 mRNA] CTD PMID:21122807 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Sele selectin E increases expression ISO Atorvastatin results in increased expression of SELE protein CTD PMID:19171469 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions EXP Atorvastatin inhibits the reaction [Fructose results in increased expression of SERPINE1 mRNA] CTD PMID:21122807 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sgk2 serum/glucocorticoid regulated kinase 2 multiple interactions ISO [Atorvastatin co-treated with NR1I2 protein] results in increased expression of SGK2 mRNA CTD PMID:24204015 NCBI chr 3:151,644,102...151,669,480
Ensembl chr 3:151,644,102...151,669,480
JBrowse link
G Sirt1 sirtuin 1 multiple interactions
increases phosphorylation
EXP
ISO
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of SIRT1 protein]
Atorvastatin results in increased phosphorylation of SIRT1 protein
CTD PMID:33073877 PMID:34939712 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc10a1 solute carrier family 10 member 1 increases expression ISO Atorvastatin results in increased expression of SLC10A1 mRNA CTD PMID:25278499 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
JBrowse link
G Slc10a2 solute carrier family 10 member 2 increases expression ISO Atorvastatin results in increased expression of SLC10A2 mRNA; Atorvastatin results in increased expression of SLC10A2 protein CTD PMID:15986414 NCBI chr16:84,386,528...84,409,475
Ensembl chr16:84,374,862...84,409,475
JBrowse link
G Slc1a2 solute carrier family 1 member 2 multiple interactions ISO Atorvastatin inhibits the reaction [APP protein results in decreased expression of SLC1A2 protein] CTD PMID:20816828 NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498
JBrowse link
G Slc1a3 solute carrier family 1 member 3 multiple interactions ISO Atorvastatin inhibits the reaction [APP protein results in decreased expression of SLC1A3 protein] CTD PMID:20816828 NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605
JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions
increases expression
ISO Atorvastatin inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]
Atorvastatin results in increased expression of SLC22A1 mRNA
CTD PMID:21641380 PMID:25278499 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions ISO Atorvastatin inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:21641380 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612
JBrowse link
G Slc22a5 solute carrier family 22 member 5 multiple interactions ISO Atorvastatin inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine] CTD PMID:21641380 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
JBrowse link
G Slc29a1 solute carrier family 29 member 1 increases expression ISO Atorvastatin results in increased expression of SLC29A1 mRNA CTD PMID:25278499 NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203
JBrowse link
G Slc2a2 solute carrier family 2 member 2 decreases expression
multiple interactions
EXP
ISO
Atorvastatin results in decreased expression of SLC2A2 protein
NR1I2 protein promotes the reaction [Atorvastatin results in decreased expression of SLC2A2 protein]
CTD PMID:26616219 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions ISO Atorvastatin inhibits the reaction [Sodium Glutamate results in decreased expression of SLC2A4 mRNA]; Atorvastatin inhibits the reaction [Sodium Glutamate results in decreased expression of SLC2A4 protein]; Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of SLC2A4 mRNA]; Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of SLC2A4 protein] CTD PMID:19800637 PMID:25834641 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) multiple interactions EXP [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite affects the localization of SLC4A1 protein] CTD PMID:20946910 NCBI chr10:87,306,865...87,323,132
Ensembl chr10:87,306,872...87,323,117
JBrowse link
G Slc6a4 solute carrier family 6 member 4 multiple interactions EXP Atorvastatin inhibits the reaction [Monocrotaline results in increased expression of SLC6A4 protein] CTD PMID:17575010 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 increases expression
decreases expression
ISO
EXP
Atorvastatin results in increased expression of SLCO1A4 mRNA; Atorvastatin results in increased expression of SLCO1A4 protein
Atorvastatin results in decreased expression of SLCO1A4 protein
CTD PMID:15986414 PMID:24909372 PMID:25278499 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 increases expression
increases uptake
multiple interactions
ISO Atorvastatin results in increased expression of SLCO1B2 mRNA
SLCO1B3 protein results in increased uptake of Atorvastatin
glimepiride affects the reaction [SLCO1B3 protein results in increased uptake of Atorvastatin]; Glyburide inhibits the reaction [SLCO1B3 protein results in increased uptake of Atorvastatin]; Nateglinide inhibits the reaction [SLCO1B3 protein results in increased uptake of Atorvastatin]; repaglinide inhibits the reaction [SLCO1B3 protein results in increased uptake of Atorvastatin]; Rosiglitazone inhibits the reaction [SLCO1B3 protein results in increased uptake of Atorvastatin]; Sulfobromophthalein inhibits the reaction [SLCO1B3 protein results in increased uptake of Atorvastatin]
CTD PMID:23121773 PMID:25106415 PMID:25278499 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 increases uptake
multiple interactions
ISO SLCO2B1 protein results in increased uptake of Atorvastatin
glimepiride inhibits the reaction [SLCO2B1 protein results in increased uptake of Atorvastatin]; Glyburide inhibits the reaction [SLCO2B1 protein results in increased uptake of Atorvastatin]; Nateglinide inhibits the reaction [SLCO2B1 protein results in increased uptake of Atorvastatin]; repaglinide inhibits the reaction [SLCO2B1 protein results in increased uptake of Atorvastatin]; Rosiglitazone inhibits the reaction [SLCO2B1 protein results in increased uptake of Atorvastatin]; Sulfobromophthalein inhibits the reaction [SLCO2B1 protein results in increased uptake of Atorvastatin]
CTD PMID:23121773 PMID:25106415 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP Atorvastatin inhibits the reaction [AGT protein results in decreased expression of SOD1 protein] CTD PMID:19451411 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
affects expression
decreases expression
increases expression
EXP
ISO
Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of SOD2 mRNA]; Quercetin affects the reaction [Atorvastatin affects the expression of SOD2 mRNA]
2-tert-butylhydroquinone inhibits the reaction [Atorvastatin affects the expression of SOD2 protein]
[PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of SOD2 protein
Atorvastatin results in decreased expression of SOD2 protein
CTD PMID:21775390 PMID:30511338 PMID:31423616 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sod3 superoxide dismutase 3 increases expression EXP Atorvastatin results in increased expression of SOD3 protein CTD PMID:19451411 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions EXP [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of SQSTM1 protein] CTD PMID:34939712 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions EXP [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of SREBF1 protein]; Atorvastatin inhibits the reaction [Fructose results in increased activity of SREBF1 protein] CTD PMID:19053045 PMID:32259528 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions
increases expression
increases localization
EXP
ISO
Atorvastatin results in increased activity of and results in increased localization of SREBF2 protein; Mevalonic Acid inhibits the reaction [Atorvastatin results in increased expression of SREBF2 mRNA]
Atorvastatin results in increased localization of SREBF2 protein
CTD PMID:11728391 PMID:12056585 PMID:12065722 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G Star steroidogenic acute regulatory protein affects expression EXP Atorvastatin affects the expression of STAR mRNA CTD PMID:29574565 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Syp synaptophysin increases expression EXP Atorvastatin results in increased expression of SYP protein CTD PMID:15255259 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745
JBrowse link
G Tfam transcription factor A, mitochondrial increases expression
decreases expression
multiple interactions
EXP
ISO
Atorvastatin results in increased expression of TFAM mRNA
Atorvastatin results in decreased expression of TFAM protein
[PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of TFAM mRNA
Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of TFAM mRNA]
CTD PMID:21775390 PMID:30511338 NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
JBrowse link
G Tfrc transferrin receptor affects expression
multiple interactions
ISO Atorvastatin affects the expression of TFRC protein
Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of TFRC protein]
CTD PMID:16387846 PMID:32976958 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP 2-chloro-5-nitrobenzanilide inhibits the reaction [Atorvastatin inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA]]; Atorvastatin inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA] CTD PMID:24161914 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Thbs1 thrombospondin 1 decreases expression ISO Atorvastatin results in decreased expression of THBS1 mRNA CTD PMID:16410222 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Tlr2 toll-like receptor 2 increases expression ISO Atorvastatin results in increased expression of TLR2 protein CTD PMID:16387846 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions
decreases expression
increases expression
ISO
EXP
[Atorvastatin co-treated with Enalapril] results in decreased expression of TLR4 mRNA; [Atorvastatin co-treated with Enalapril] results in decreased expression of TLR4 protein; [Atorvastatin co-treated with Telmisartan] results in decreased expression of TLR4 mRNA; [Atorvastatin co-treated with Telmisartan] results in decreased expression of TLR4 protein
Atorvastatin inhibits the reaction [[Dietary Fats co-treated with Ergocalciferols] results in increased expression of TLR4 mRNA]; Atorvastatin inhibits the reaction [[Dietary Fats co-treated with Ergocalciferols] results in increased expression of TLR4 protein]; Atorvastatin inhibits the reaction [Paraquat results in increased expression of TLR4 mRNA]; Atorvastatin inhibits the reaction [Paraquat results in increased expression of TLR4 protein]
Atorvastatin results in decreased expression of TLR4 mRNA; Atorvastatin results in decreased expression of TLR4 protein
Atorvastatin results in increased expression of TLR4 protein
CTD PMID:16387846 PMID:20524934 PMID:27883937 PMID:38213245 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
decreases secretion
ISO
EXP
Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of TNF mRNA]; Atorvastatin inhibits the reaction [Air Pollutants results in increased expression of TNF protein]; Atorvastatin inhibits the reaction [Particulate Matter results in increased expression of TNF mRNA]; Atorvastatin inhibits the reaction [Particulate Matter results in increased expression of TNF protein]; Atorvastatin inhibits the reaction [TNF protein results in decreased expression of and results in decreased secretion of FASLG protein modified form]; Atorvastatin inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Atorvastatin inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]; Atorvastatin inhibits the reaction [TNF results in increased expression of ICAM1]; Atorvastatin inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Atorvastatin inhibits the reaction [TNF results in increased expression of ITGAL]; Atorvastatin inhibits the reaction [TNF results in increased expression of ITGB2]; Atorvastatin promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Mevalonic Acid inhibits the reaction [Atorvastatin inhibits the reaction [TNF results in increased expression of CCL2 mRNA]]; Mevalonic Acid inhibits the reaction [Atorvastatin inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]]; Mevalonic Acid inhibits the reaction [Atorvastatin inhibits the reaction [TNF results in increased expression of IL6 mRNA]]
Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF mRNA]; Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF protein]; Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of TNF mRNA]; Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of TNF protein]
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of TNF protein]; Atorvastatin inhibits the reaction [[Dietary Fats co-treated with Ergocalciferols] results in increased expression of TNF protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Atorvastatin inhibits the reaction [TNF protein results in decreased expression of PDK4 protein]; Atorvastatin inhibits the reaction [TNF protein results in decreased expression of PPARGC1A protein]; Atorvastatin inhibits the reaction [TNF protein results in increased oxidation of Glucose]; Farnesol inhibits the reaction [Atorvastatin inhibits the reaction [TNF protein results in decreased expression of PPARGC1A protein]]; Mevalonic Acid inhibits the reaction [Atorvastatin inhibits the reaction [TNF protein results in decreased expression of PDK4 protein]]
Atorvastatin results in decreased expression of TNF mRNA
Atorvastatin results in decreased secretion of TNF protein
Atorvastatin results in decreased expression of TNF protein
CTD PMID:12117737 PMID:12615677 PMID:15063428 PMID:16387846 PMID:17521631 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A decreases expression ISO Atorvastatin results in decreased expression of TNFRSF1A protein CTD PMID:16360360 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tnfsf10 TNF superfamily member 10 increases response to substance ISO TNFSF10 protein results in increased susceptibility to Atorvastatin CTD PMID:21910007 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tomm20 translocase of outer mitochondrial membrane 20 multiple interactions
increases expression
ISO [PPARGC1B protein affects the susceptibility to Atorvastatin] which affects the expression of TOMM20 protein
Atorvastatin results in increased expression of TOMM20 protein
CTD PMID:30511338 NCBI chr19:54,925,197...54,935,188
Ensembl chr19:54,923,402...54,935,198
JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions
ISO Atorvastatin results in increased expression of TP53 protein
Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of TRP53 protein]
CTD PMID:29630879 PMID:37121058 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Traf6 TNF receptor associated factor 6 multiple interactions ISO [Atorvastatin co-treated with Enalapril] results in decreased expression of TRAF6 mRNA; [Atorvastatin co-treated with Telmisartan] results in decreased expression of TRAF6 mRNA CTD PMID:20524934 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
JBrowse link
G Tubb3 tubulin, beta 3 class III increases expression EXP Atorvastatin results in increased expression of TUBB3 protein CTD PMID:15255259 NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 decreases expression
multiple interactions
ISO
EXP
Atorvastatin results in decreased expression of VCAM1 mRNA; Atorvastatin results in decreased expression of VCAM1 protein
Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of VCAM1 protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of VCAM1 protein]
CTD PMID:17589825 PMID:17673219 PMID:22245985 PMID:25058445 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vegfd vascular endothelial growth factor D affects expression ISO Atorvastatin affects the expression of VEGFD mRNA CTD PMID:16410222 NCBI chr  X:30,073,122...30,108,413
Ensembl chr  X:30,074,163...30,108,295
JBrowse link
G Vim vimentin multiple interactions EXP [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of VIM protein] CTD PMID:34939712 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Vwf von Willebrand factor increases expression ISO Atorvastatin results in increased expression of VWF protein CTD PMID:19171469 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539
JBrowse link
G Wt1 WT1 transcription factor multiple interactions EXP [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of WT1 protein] CTD PMID:34939712 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
JBrowse link
G Xirp1 xin actin-binding repeat containing 1 multiple interactions ISO [Buthionine Sulfoximine co-treated with Atorvastatin co-treated with Ciprofloxacin] results in increased expression of XIRP1 mRNA CTD PMID:29679711 NCBI chr 8:119,744,778...119,757,547
Ensembl chr 8:119,747,419...119,757,349
JBrowse link
barium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions EXP [barium chloride results in increased abundance of Barium] which results in decreased activity of ACHE protein CTD PMID:31407482 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Alb albumin multiple interactions
increases secretion
EXP Plant Extracts inhibits the reaction [barium chloride results in increased secretion of ALB protein] CTD PMID:26732703 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Cat catalase multiple interactions
decreases activity
EXP [[Sodium Selenite results in increased abundance of Selenium] which co-treated with Ascorbic Acid] inhibits the reaction [barium chloride results in decreased activity of CAT protein]; [barium chloride results in increased abundance of Barium] which results in decreased activity of CAT protein; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [barium chloride results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [barium chloride results in decreased activity of CAT protein]; Plant Extracts inhibits the reaction [barium chloride results in decreased activity of CAT protein] CTD PMID:26732703 PMID:27941167 PMID:28683652 PMID:31407482 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO barium chloride inhibits the reaction [TNF protein results in increased expression of F3 mRNA]; barium chloride inhibits the reaction [TNF protein results in increased expression of F3 protein] CTD PMID:23305835 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases activity EXP barium chloride results in increased activity of GGT1 protein CTD PMID:28683652 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases activity EXP barium chloride results in increased activity of GOT1 protein CTD PMID:28683652 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity EXP barium chloride results in increased activity of GPT protein CTD PMID:28683652 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases activity EXP barium chloride results in decreased activity of GPX1 protein CTD PMID:28683652 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
EXP barium chloride results in increased expression of IL1B mRNA
Plant Extracts inhibits the reaction [barium chloride results in increased expression of IL1B mRNA]
CTD PMID:26732703 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
EXP barium chloride results in increased expression of IL6 mRNA
[barium chloride results in increased abundance of Barium] which results in increased expression of IL6 protein; Plant Extracts inhibits the reaction [barium chloride results in increased expression of IL6 mRNA]
CTD PMID:26732703 PMID:31407482 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 multiple interactions ISO barium chloride results in decreased activity of [KCNQ1 protein binds to KCNE1 protein] CTD PMID:16909339 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 multiple interactions EXP barium chloride inhibits the reaction [KCNJ2 protein results in increased transport of Potassium] CTD PMID:11087224 NCBI chr10:96,060,834...96,071,397
Ensembl chr10:96,060,821...96,071,445
JBrowse link
G Kcnk3 potassium two pore domain channel subfamily K member 3 decreases activity EXP barium chloride results in decreased activity of KCNK3 protein CTD PMID:16020457 NCBI chr 6:25,761,487...25,799,153
Ensembl chr 6:25,763,228...25,799,153
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 multiple interactions ISO barium chloride results in decreased activity of [KCNQ1 protein binds to KCNE1 protein] CTD PMID:16909339 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Ldha lactate dehydrogenase A increases activity EXP barium chloride results in increased activity of LDHA protein CTD PMID:28683652 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
G Mt2A metallothionein 2A increases expression
multiple interactions
EXP barium chloride results in increased expression of MT2A mRNA
Plant Extracts inhibits the reaction [barium chloride results in increased expression of MT2A mRNA]
CTD PMID:26732703 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Serpine1 serpin family E member 1 increases secretion EXP barium chloride results in increased secretion of SERPINE1 protein CTD PMID:21596853 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression
multiple interactions
EXP barium chloride results in decreased expression of SOD2 mRNA
Plant Extracts inhibits the reaction [barium chloride results in decreased expression of SOD2 mRNA]
CTD PMID:26732703 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Stx1a syntaxin 1A multiple interactions
affects localization
EXP Propofol inhibits the reaction [barium chloride affects the localization of STX1A protein]; STX1A protein modified form inhibits the reaction [Propofol inhibits the reaction [barium chloride affects the localization of STX1A protein]] CTD PMID:29320738 NCBI chr12:21,641,971...21,670,022
Ensembl chr12:21,641,969...21,669,930
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP
ISO
Plant Extracts inhibits the reaction [barium chloride results in increased expression of TNF mRNA]
barium chloride inhibits the reaction [TNF protein results in increased expression of F3 mRNA]; barium chloride inhibits the reaction [TNF protein results in increased expression of F3 protein]
CTD PMID:23305835 PMID:26732703 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO [barium chloride results in increased abundance of Barium] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:104,217,898...104,277,886
Ensembl chr  X:104,217,925...104,276,861
JBrowse link
barium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmbs hydroxymethylbilane synthase decreases activity EXP Barium ion decreases activity of purified Hmbs protein RGD PMID:6732900 RGD:25394584 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957
JBrowse link
barium sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin increases expression EXP Barium Sulfate results in increased expression of ALB mRNA CTD PMID:29463257 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression EXP Barium Sulfate results in increased expression of BIRC5 mRNA CTD PMID:29463257 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression EXP Barium Sulfate results in increased expression of CCL11 mRNA CTD PMID:29463257 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases secretion
increases expression
EXP Barium Sulfate results in increased secretion of CCL2 protein
Barium Sulfate results in increased expression of CCL2 mRNA
CTD PMID:29463257 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 affects expression EXP Barium Sulfate affects the expression of CCL20 mRNA CTD PMID:29463257 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 increases expression EXP Barium Sulfate results in increased expression of CCL22 mRNA CTD PMID:29463257 NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400
JBrowse link
G Ccl24 C-C motif chemokine ligand 24 increases expression EXP Barium Sulfate results in increased expression of CCL24 mRNA CTD PMID:29463257 NCBI chr12:21,100,835...21,104,832
Ensembl chr12:21,100,835...21,104,893
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression EXP Barium Sulfate results in decreased expression of CCL4 mRNA CTD PMID:29463257 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression EXP Barium Sulfate results in increased expression of CCL7 mRNA CTD PMID:29463257 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression EXP Barium Sulfate results in increased expression of CCR2 mRNA CTD PMID:29463257 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Cd40lg CD40 ligand decreases expression EXP Barium Sulfate results in decreased expression of CD40LG mRNA CTD PMID:29463257 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression EXP Barium Sulfate results in increased expression of CXCL9 mRNA CTD PMID:29463257 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 increases expression EXP Barium Sulfate results in increased expression of CXCR3 mRNA CTD PMID:29463257 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP Barium Sulfate results in increased expression of CYP4A1 mRNA CTD PMID:11124224 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 increases expression EXP Barium Sulfate results in increased expression of CYP4A2 mRNA CTD PMID:11124224 NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165
JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 increases expression EXP Barium Sulfate results in increased expression of CYP4A3 mRNA CTD PMID:11124224 NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 increases expression EXP Barium Sulfate results in increased expression of CYP4F1 mRNA CTD PMID:14644421 NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046
JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 increases expression EXP Barium Sulfate results in increased expression of CYP4F4 mRNA CTD PMID:14644421 NCBI chr 7:11,717,208...11,733,507
Ensembl chr 7:11,717,208...11,733,506
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 increases expression EXP Barium Sulfate results in increased expression of CYP4F6 mRNA CTD PMID:14644421 NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782
JBrowse link
G Exo1 exonuclease 1 affects expression EXP Barium Sulfate affects the expression of EXO1 mRNA CTD PMID:29463257 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression EXP Barium Sulfate results in decreased expression of FABP4 mRNA CTD PMID:29463257 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 decreases expression EXP Barium Sulfate results in decreased expression of HBA1 mRNA CTD PMID:29463257 NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392
JBrowse link
G Il2rb interleukin 2 receptor subunit beta decreases expression EXP Barium Sulfate results in decreased expression of IL2RB mRNA CTD PMID:29463257 NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054
JBrowse link
G Il6 interleukin 6 increases expression ISO Barium Sulfate results in increased expression of IL6 protein CTD PMID:11403239 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Krt1 keratin 1 increases expression EXP Barium Sulfate results in increased expression of KRT1 mRNA CTD PMID:29463257 NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844
JBrowse link
G Lig4 DNA ligase 4 increases expression EXP Barium Sulfate results in increased expression of LIG4 mRNA CTD PMID:29463257 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040
JBrowse link
G Lpo lactoperoxidase increases expression EXP Barium Sulfate results in increased expression of LPO mRNA; Barium Sulfate results in increased expression of LPO protein CTD PMID:29463257 NCBI chr10:72,606,950...72,626,220
Ensembl chr10:72,606,944...72,626,535
JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression EXP Barium Sulfate results in increased expression of MMP12 mRNA; Barium Sulfate results in increased expression of MMP12 protein CTD PMID:29463257 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
G Mutyh mutY DNA glycosylase increases expression EXP Barium Sulfate results in increased expression of MUTYH mRNA CTD PMID:29463257 NCBI chr 5:130,274,034...130,286,149
Ensembl chr 5:130,274,122...130,286,146
JBrowse link
G Ngb neuroglobin decreases expression EXP Barium Sulfate results in decreased expression of NGB mRNA CTD PMID:29463257 NCBI chr 6:106,744,378...106,749,830
Ensembl chr 6:106,744,378...106,749,830
JBrowse link
G Noxo1 NADPH oxidase organizer 1 increases expression EXP Barium Sulfate results in increased expression of NOXO1 mRNA CTD PMID:29463257 NCBI chr10:13,723,253...13,726,008
Ensembl chr10:13,721,473...13,726,061
JBrowse link
G Opcml opioid binding protein/cell adhesion molecule-like increases expression EXP Barium Sulfate results in increased expression of OPCML mRNA CTD PMID:29463257 NCBI chr 8:26,788,988...27,304,551
Ensembl chr 8:26,192,841...27,300,620
JBrowse link
G Pf4 platelet factor 4 increases expression EXP Barium Sulfate results in increased expression of PF4 mRNA CTD PMID:29463257 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Scd stearoyl-CoA desaturase affects expression EXP Barium Sulfate affects the expression of SCD1 mRNA CTD PMID:29463257 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Tcf21 transcription factor 21 decreases expression EXP Barium Sulfate results in decreased expression of TCF21 mRNA CTD PMID:29463257 NCBI chr 1:22,701,353...22,704,212
Ensembl chr 1:22,701,353...22,704,202
JBrowse link
G Thbs2 thrombospondin 2 increases expression EXP Barium Sulfate results in increased expression of THBS2 mRNA CTD PMID:29463257 NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789
JBrowse link
G Top2a DNA topoisomerase II alpha increases expression EXP Barium Sulfate results in increased expression of TOP2A mRNA CTD PMID:29463257 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Txnip thioredoxin interacting protein decreases expression EXP Barium Sulfate results in decreased expression of TXNIP mRNA CTD PMID:29463257 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Xrcc2 X-ray repair cross complementing 2 increases expression EXP Barium Sulfate results in increased expression of XRCC2 mRNA CTD PMID:29463257 NCBI chr 4:9,423,873...9,502,980
Ensembl chr 4:9,423,898...9,442,482
JBrowse link
barium(0) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions EXP [barium chloride results in increased abundance of Barium] which results in decreased activity of ACHE protein CTD PMID:31407482 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Adra1a adrenoceptor alpha 1A multiple interactions ISO ADRA1A protein promotes the reaction [TRPC6 protein results in increased transport of Barium] CTD PMID:11179201 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A increases transport EXP CACNA1A protein results in increased transport of Barium CTD PMID:11313431 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225
JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B affects transport
increases transport
multiple interactions
ISO CACNA1B gene polymorphism affects the transport of Barium
CACNA1B protein results in increased transport of Barium
[GNB1 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB1 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB1 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB5 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; Cadmium Chloride inhibits the reaction [CACNA1B protein results in increased transport of Barium]
CTD PMID:11007869 PMID:11756491 PMID:14559144 NCBI chr 3:7,380,892...7,546,104
Ensembl chr 3:7,380,922...7,546,091
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C increases transport EXP CACNA1C protein results in increased transport of Barium CTD PMID:17569661 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D affects transport
multiple interactions
increases transport
ISO
EXP
CACNA1D protein affects the transport of Barium
CACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Barium]
CACNA1D protein results in increased transport of Barium
CTD PMID:15357422 PMID:17567805 PMID:27798183 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215
JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E increases transport
multiple interactions
affects transport
ISO
EXP
CACNA1E mRNA alternative form results in increased transport of Barium; CACNA1E protein results in increased transport of Barium
1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid affects the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; 4-O-methyl-12-O-tetradecanoylphorbol 13-acetate affects the reaction [CACNA1E protein results in increased transport of Barium]; Atropine inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; Calcium inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; Heparin affects the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; Isradipine inhibits the reaction [CACNA1E protein results in increased transport of Barium]; Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]; Nickel inhibits the reaction [CACNA1E protein results in increased transport of Barium]; omega-conotoxin-MVIIC promotes the reaction [Isradipine inhibits the reaction [CACNA1E protein results in increased transport of Barium]]; Ro 31-8425 inhibits the reaction [4-O-methyl-12-O-tetradecanoylphorbol 13-acetate affects the reaction [CACNA1E protein results in increased transport of Barium]]; Ro 31-8425 inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; SNX 482 inhibits the reaction [CACNA1E protein results in increased transport of Barium]
SNX 482 inhibits the reaction [CACNA1E mRNA alternative form results in increased transport of Barium]
CACNA1E protein affects the transport of Barium
CTD PMID:10627594 PMID:10669483 PMID:11102459 PMID:11179973 PMID:12663092 More... NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450
JBrowse link
G Cacna1f calcium voltage-gated channel subunit alpha1 F multiple interactions
increases transport
ISO 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester promotes the reaction [CACNA1F protein results in increased transport of Barium]; Diltiazem inhibits the reaction [CACNA1F protein results in increased transport of Barium]; Isradipine inhibits the reaction [CACNA1F protein results in increased transport of Barium]; Verapamil inhibits the reaction [CACNA1F protein results in increased transport of Barium] CTD PMID:14744918 NCBI chr  X:14,868,096...14,896,413
Ensembl chr  X:14,868,024...14,896,413
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G increases transport
multiple interactions
ISO CACNA1G mRNA alternative form results in increased transport of Barium; CACNA1G protein results in increased transport of Barium
Cerium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Erbium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Gadolinium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Holmium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Lanthanum inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Neodymium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Scandium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Ytterbium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Yttrium inhibits the reaction [CACNA1G protein results in increased transport of Barium]
CTD PMID:11179973 PMID:12163980 NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H increases transport ISO CACNA1H mRNA alternative form results in increased transport of Barium CTD PMID:11179973 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I increases transport ISO CACNA1I mRNA alternative form results in increased transport of Barium CTD PMID:11179973 NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 affects transport
increases transport
ISO
EXP
CACNA2D1 protein affects the transport of Barium
CACNA2D1 protein results in increased transport of Barium
CTD PMID:11313431 PMID:15245474 PMID:15474003 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969
JBrowse link
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 multiple interactions ISO CACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Barium] CTD PMID:27798183 NCBI chr 8:108,072,208...108,203,516
Ensembl chr 8:108,072,454...108,203,173
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 affects transport ISO CACNB3 protein affects the transport of Barium CTD PMID:15245474 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074
JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 affects transport ISO
EXP
CACNB4 protein affects the transport of Barium CTD PMID:11313431 PMID:15245474 NCBI chr 3:36,906,771...37,169,165
Ensembl chr 3:36,910,427...37,168,944
JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 affects transport ISO CACNG2 protein affects the transport of Barium CTD PMID:11313431 NCBI chr 7:109,572,838...109,698,516
Ensembl chr 7:109,574,459...109,697,227
JBrowse link
G Cacng3 calcium voltage-gated channel auxiliary subunit gamma 3 affects transport ISO CACNG3 protein affects the transport of Barium CTD PMID:11313431 NCBI chr 1:177,201,361...177,297,019
Ensembl chr 1:177,201,288...177,297,024
JBrowse link
G Cat catalase multiple interactions EXP [barium chloride results in increased abundance of Barium] which results in decreased activity of CAT protein CTD PMID:31407482 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit multiple interactions ISO 1-Butanol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 1-Propanol promotes the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 2-butanol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 2-Propanol promotes the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; [CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium; Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]; crotonyl alcohol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; isobutyl alcohol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; n-pentanol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; tert-Butyl Alcohol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]] CTD PMID:11821649 NCBI chr15:40,342,317...40,358,601
Ensembl chr15:40,342,317...40,358,601
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP [CHRNA4 protein co-treated with CHRNB2 protein] affects the reaction [Barium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein mutant form co-treated with CHRNB2 protein] inhibits the reaction [Barium results in increased susceptibility to Acetylcholine] CTD PMID:12754307 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions EXP [CHRNA4 protein co-treated with CHRNB2 protein] affects the reaction [Barium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein mutant form co-treated with CHRNB2 protein] inhibits the reaction [Barium results in increased susceptibility to Acetylcholine] CTD PMID:12754307 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit multiple interactions ISO 1-Butanol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 1-Propanol promotes the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 2-butanol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 2-Propanol promotes the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; [CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium; Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]; crotonyl alcohol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; isobutyl alcohol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; n-pentanol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; tert-Butyl Alcohol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]] CTD PMID:11821649 NCBI chr 8:55,417,583...55,437,027
Ensembl chr 8:55,418,313...55,437,027
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
decreases transport
EXP 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester inhibits the reaction [DRD2 protein results in decreased transport of Barium]; [DRD2 protein affects the abundance of Calcium] which results in decreased transport of Barium; [DRD2 protein results in increased activity of PLCB1 protein] which results in decreased transport of Barium; DRD2 protein affects the reaction [N-n-propylnorapomorphine analog results in decreased transport of Barium]; DRD2 protein affects the reaction [Quinpirole results in decreased transport of Barium]; Nifedipine inhibits the reaction [DRD2 protein affects the reaction [Quinpirole results in decreased transport of Barium]] CTD PMID:11124974 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G F2 coagulation factor II, thrombin increases uptake
multiple interactions
ISO F2 protein results in increased uptake of Barium
Nickel inhibits the reaction [F2 protein results in increased uptake of Barium]
CTD PMID:2125206 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions ISO Barium inhibits the reaction [F2RL1 protein results in increased transport of Chlorides]; F2RL1 protein affects the reaction [1-oleoyl-2-acetoyl-sn-glycerol results in increased transport of Barium] CTD PMID:11804840 PMID:16123040 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 decreases activity ISO Barium results in decreased activity of FXYD2 protein CTD PMID:11533133 NCBI chr 8:45,712,901...45,720,032
Ensembl chr 8:45,712,903...45,720,203
JBrowse link
G Gnb1 G protein subunit beta 1 multiple interactions ISO [GNB1 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB1 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB1 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124
JBrowse link
G Gnb2 G protein subunit beta 2 multiple interactions ISO [GNB2 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr12:19,159,002...19,164,021
Ensembl chr12:19,158,973...19,164,019
JBrowse link
G Gnb3 G protein subunit beta 3 multiple interactions ISO [GNB3 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr 4:157,639,468...157,645,171
Ensembl chr 4:157,639,469...157,645,173
JBrowse link
G Gnb4 G protein subunit beta 4 multiple interactions ISO [GNB4 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr 2:115,360,746...115,400,680
Ensembl chr 2:115,364,918...115,400,579
JBrowse link
G Gnb5 G protein subunit beta 5 multiple interactions ISO [GNB5 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr 8:76,076,120...76,105,069
Ensembl chr 8:76,073,306...76,105,069
JBrowse link
G Gng2 G protein subunit gamma 2 multiple interactions ISO [GNB1 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB5 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr15:4,316,038...4,416,918
Ensembl chr15:4,316,059...4,417,183
JBrowse link
G Gng3 G protein subunit gamma 3 multiple interactions ISO [GNB1 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr 1:205,731,837...205,733,603
Ensembl chr 1:205,731,837...205,733,603
JBrowse link
G Gngt1 G protein subunit gamma transducin 1 multiple interactions ISO [GNB1 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr 4:32,006,267...32,009,252
Ensembl chr 4:32,006,267...32,009,252
JBrowse link
G Il6 interleukin 6 multiple interactions EXP [barium chloride results in increased abundance of Barium] which results in increased expression of IL6 protein CTD PMID:31407482 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Kcna10 potassium voltage-gated channel subfamily A member 10 multiple interactions ISO Barium inhibits the reaction [KCNA10 protein results in increased transport of Potassium] CTD PMID:10836990 NCBI chr 2:194,786,500...194,798,575
Ensembl chr 2:194,786,500...194,798,575
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 multiple interactions ISO Barium results in decreased activity of [KCNQ1 protein binds to KCNE1 protein] CTD PMID:16909339 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901
JBrowse link
G Kcnh1 potassium voltage-gated channel subfamily H member 1 decreases activity ISO Barium results in decreased activity of KCNH1 protein CTD PMID:10896755 NCBI chr13:103,722,140...104,024,762
Ensembl chr13:103,722,245...104,024,740
JBrowse link
G Kcnh3 potassium voltage-gated channel subfamily H member 3 multiple interactions ISO Barium binds to and results in decreased activity of KCNH3 protein CTD PMID:12193184 NCBI chr 7:130,365,593...130,383,859
Ensembl chr 7:130,366,011...130,383,855
JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 decreases activity EXP Barium results in decreased activity of KCNJ10 protein CTD PMID:16331678 PMID:17978865 NCBI chr13:84,802,026...84,835,383
Ensembl chr13:84,802,009...84,835,461
JBrowse link
G Kcnj12 potassium inwardly-rectifying channel, subfamily J, member 12 multiple interactions ISO Barium inhibits the reaction [KCNJ12 protein results in increased transport of Potassium] CTD PMID:15958527 NCBI chr10:45,696,621...45,745,528
Ensembl chr10:45,696,849...45,745,492
JBrowse link
G Kcnj14 potassium inwardly-rectifying channel, subfamily J, member 14 multiple interactions ISO
EXP
Barium inhibits the reaction [KCNJ14 protein results in increased transport of Potassium] CTD PMID:10938328 PMID:17347781 NCBI chr 1:96,293,159...96,300,810
Ensembl chr 1:96,293,435...96,495,459
JBrowse link
G Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 decreases activity ISO Barium results in decreased activity of KCNJ15 protein CTD PMID:15328350 NCBI chr11:34,577,397...34,621,725
Ensembl chr11:34,577,363...34,621,952
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 multiple interactions
decreases activity
ISO Barium inhibits the reaction [KCNJ2 protein results in increased transport of Potassium]
Barium results in decreased activity of KCNJ2 protein
CTD PMID:12598232 PMID:15958527 PMID:17347781 PMID:17699636 NCBI chr10:96,060,834...96,071,397
Ensembl chr10:96,060,821...96,071,445
JBrowse link
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 decreases activity
multiple interactions
ISO Barium results in decreased activity of KCNJ4 protein
Barium inhibits the reaction [KCNJ4 protein results in increased transport of Potassium]
CTD PMID:12598232 PMID:17091215 NCBI chr 7:111,047,097...111,074,151
Ensembl chr 7:111,047,094...111,074,151
JBrowse link
G Kcnk1 potassium two pore domain channel subfamily K member 1 multiple interactions ISO Barium inhibits the reaction [KCNK1 protein results in increased transport of Potassium]; Barium inhibits the reaction [KCNK1 protein results in increased transport of Sodium] CTD PMID:16847696 NCBI chr19:53,959,411...53,997,726
Ensembl chr19:53,959,657...53,997,724
JBrowse link
G Kcnk18 potassium two pore domain channel subfamily K member 18 multiple interactions ISO Barium inhibits the reaction [KCNK18 protein results in increased transport of Potassium] CTD PMID:12754259 NCBI chr 1:258,374,671...258,388,945
Ensembl chr 1:258,374,671...258,388,945
JBrowse link
G Kcnk9 potassium two pore domain channel subfamily K member 9 multiple interactions EXP Barium inhibits the reaction [KCNK9 protein results in increased transport of Potassium] CTD PMID:10734076 NCBI chr 7:104,429,186...104,473,924
Ensembl chr 7:104,437,934...104,473,175
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 multiple interactions ISO Barium results in decreased activity of [KCNQ1 protein binds to KCNE1 protein] CTD PMID:16909339 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Mir30a microRNA 30a multiple interactions ISO [Air Pollutants, Occupational results in increased abundance of Barium] which results in decreased expression of MIR30A mRNA CTD PMID:27506416 NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670
JBrowse link
G Mmp14 matrix metallopeptidase 14 increases expression ISO Barium results in increased expression of MMP14 protein CTD PMID:23804419 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Npr3 natriuretic peptide receptor 3 multiple interactions ISO Barium inhibits the reaction [NPR3 protein affects the reaction [Enterotoxins affects the transport of Potassium]]; Barium inhibits the reaction [NPR3 protein affects the reaction [guanylin affects the transport of Potassium]] CTD PMID:11889121 NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955
JBrowse link
G P2rx7 purinergic receptor P2X 7 multiple interactions ISO P2RX7 protein affects the reaction [Adenosine Triphosphate results in increased transport of Barium] CTD PMID:11003599 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Plcb1 phospholipase C beta 1 multiple interactions EXP [DRD2 protein results in increased activity of PLCB1 protein] which results in decreased transport of Barium CTD PMID:11124974 NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869
JBrowse link
G Ptk2 protein tyrosine kinase 2 increases phosphorylation ISO Barium results in increased phosphorylation of PTK2 protein CTD PMID:23804419 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 multiple interactions ISO Barium inhibits the reaction [SGK1 protein results in increased transport of Potassium] CTD PMID:12590200 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
JBrowse link
G Sgk2 serum/glucocorticoid regulated kinase 2 multiple interactions ISO Barium inhibits the reaction [SGK2 protein results in increased transport of Potassium] CTD PMID:12590200 NCBI chr 3:151,644,102...151,669,480
Ensembl chr 3:151,644,102...151,669,480
JBrowse link
G Sgk3 serum/glucocorticoid regulated kinase family, member 3 multiple interactions ISO Barium inhibits the reaction [SGK3 protein results in increased transport of Potassium] CTD PMID:12590200 NCBI chr 5:9,345,761...9,472,243
Ensembl chr 5:9,346,040...9,415,476
JBrowse link
G Slc12a4 solute carrier family 12 member 4 multiple interactions ISO Barium inhibits the reaction [SLC12A4 protein results in increased transport of Potassium] CTD PMID:11703599 NCBI chr19:33,838,418...33,860,369
Ensembl chr19:33,838,419...33,860,331
JBrowse link
G Slc12a7 solute carrier family 12 member 7 decreases activity ISO Barium results in decreased activity of SLC12A7 protein CTD PMID:10913127 NCBI chr 1:29,472,692...29,554,246
Ensembl chr 1:29,472,692...29,554,302
JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions ISO Barium promotes the reaction [SLC22A12 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:15284287 NCBI chr 1:203,845,039...203,852,496
Ensembl chr 1:203,845,048...203,853,555
JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions ISO Barium inhibits the reaction [SLC22A3 protein results in increased uptake of Tetraethylammonium] CTD PMID:10966924 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612
JBrowse link
G Slc8a1 solute carrier family 8 member A1 affects transport ISO SLC8A1 protein affects the transport of Barium CTD PMID:17560225 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [[Industrial Waste results in increased abundance of Trace Elements] which results in increased abundance of Barium] which affects the expression of SOD1 mRNA CTD PMID:34083740 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Barium inhibits the reaction [TNF protein results in increased transport of Potassium] CTD PMID:10783394 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 multiple interactions
increases transport
ISO 1-oleoyl-2-acetylglycerol promotes the reaction [TRPC3 protein results in increased transport of Barium]
1-oleoyl-2-acetoyl-sn-glycerol affects the reaction [TRPC3 protein results in increased transport of Barium]
CTD PMID:11042129 PMID:16055711 NCBI chr 2:119,481,313...119,619,333
Ensembl chr 2:119,481,400...119,558,855
JBrowse link
G Trpc4 transient receptor potential cation channel, subfamily C, member 4 multiple interactions
increases transport
ISO TRPC4 protein affects the reaction [Carbachol results in increased transport of Barium]
TRPC4 protein results in increased transport of Barium
CTD PMID:11042129 PMID:11830588 NCBI chr 2:138,307,676...138,476,856
Ensembl chr 2:138,308,084...138,476,768
JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 multiple interactions
increases transport
affects transport
ISO 1-oleoyl-2-acetoyl-sn-glycerol affects the reaction [TRPC6 protein affects the transport of Barium]; ADRA1A protein promotes the reaction [TRPC6 protein results in increased transport of Barium] CTD PMID:11179201 PMID:16055711 NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092
JBrowse link
G Trpm6 transient receptor potential cation channel, subfamily M, member 6 multiple interactions ISO TRPM6 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Barium]; TRPM6 protein affects the reaction [1-stearoyl-2-arachidonoylglycerol results in increased transport of Barium] CTD PMID:11988098 NCBI chr 1:216,136,407...216,320,523
Ensembl chr 1:216,170,038...216,320,520
JBrowse link
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 increases uptake ISO TRPV6 protein results in increased uptake of Barium CTD PMID:19996302 PMID:21146870 NCBI chr 4:70,507,347...70,523,013
Ensembl chr 4:70,507,348...70,523,017
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO [barium chloride results in increased abundance of Barium] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:104,217,898...104,277,886
Ensembl chr  X:104,217,925...104,276,861
JBrowse link
G Urod uroporphyrinogen decarboxylase affects abundance ISO UROD protein affects the abundance of Barium CTD PMID:16325539 NCBI chr 5:130,464,695...130,468,783
Ensembl chr 5:130,455,217...130,468,808
JBrowse link
beryllium atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions EXP [Beryllium results in increased methylation of CDKN2A promoter] which results in decreased expression of CDKN2A mRNA CTD PMID:11872642 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Esr1 estrogen receptor 1 increases methylation EXP Beryllium results in increased methylation of ESR1 gene CTD PMID:11872642 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Hras HRas proto-oncogene, GTPase increases mutagenesis EXP Beryllium results in increased mutagenesis of HRAS gene CTD PMID:7545909 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Il1b interleukin 1 beta increases expression
affects expression
ISO Beryllium results in increased expression of IL1B mRNA
Beryllium affects the expression of IL1B mRNA
CTD PMID:8473757 PMID:8629860 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G RT1-Hb-ps1 RT1 class II, locus Hb, pseudogene 1 affects binding
increases response to substance
ISO HLA-DPB1 protein mutant form binds to Beryllium
HLA-DPB1 gene polymorphism results in increased susceptibility to Beryllium; HLA-DPB1 gene SNP results in increased susceptibility to Beryllium; HLA-DPB1 protein mutant form results in increased susceptibility to Beryllium
CTD PMID:11551429 PMID:15273960 PMID:17956852 NCBI chr20:4,775,598...4,779,590
Ensembl chr20:4,774,650...4,780,618
JBrowse link
G Tnf tumor necrosis factor increases response to substance
increases secretion
increases expression
ISO TNF promoter polymorphism results in increased susceptibility to Beryllium
Beryllium results in increased secretion of TNF protein
Beryllium results in increased expression of TNF mRNA
CTD PMID:8629860 PMID:12449171 PMID:15127972 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
beryllium dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 affects expression ISO beryllium chloride affects the expression of APEX1 mRNA CTD PMID:23793613 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase affects expression ISO beryllium chloride affects the expression of OGG1 mRNA CTD PMID:23793613 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Tp53 tumor protein p53 increases expression ISO beryllium chloride results in increased expression of TRP53 mRNA CTD PMID:23793613 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
beryllium difluoride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO beryllium fluoride promotes the reaction [ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate] CTD PMID:11027628 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 multiple interactions EXP beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]; Cobalt promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]]; Magnesium Chloride promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]]; Manganese promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]]; Nickel promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]] CTD PMID:12069597 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
JBrowse link
G Abcc8 ATP binding cassette subfamily C member 8 decreases activity ISO
EXP
beryllium fluoride results in decreased activity of ABCC8 protein CTD PMID:17561960 PMID:18025464 NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression ISO beryllium fluoride results in increased expression of CREB1 protein CTD PMID:11867686 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO beryllium fluoride results in increased expression of FOS protein CTD PMID:11867686 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 increases phosphorylation ISO beryllium fluoride results in increased phosphorylation of MAP2K1 protein CTD PMID:11867686 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO beryllium fluoride results in increased phosphorylation of MAPK3 protein CTD PMID:11867686 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO beryllium fluoride results in increased expression of MYC protein CTD PMID:11867686 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
beryllium dihydride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions EXP [Beryllium results in increased methylation of CDKN2A promoter] which results in decreased expression of CDKN2A mRNA CTD PMID:11872642 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Esr1 estrogen receptor 1 increases methylation EXP Beryllium results in increased methylation of ESR1 gene CTD PMID:11872642 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Hras HRas proto-oncogene, GTPase increases mutagenesis EXP Beryllium results in increased mutagenesis of HRAS gene CTD PMID:7545909 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Il1b interleukin 1 beta increases expression
affects expression
ISO Beryllium results in increased expression of IL1B mRNA
Beryllium affects the expression of IL1B mRNA
CTD PMID:8473757 PMID:8629860 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G RT1-Hb-ps1 RT1 class II, locus Hb, pseudogene 1 affects binding
increases response to substance
ISO HLA-DPB1 protein mutant form binds to Beryllium
HLA-DPB1 gene polymorphism results in increased susceptibility to Beryllium; HLA-DPB1 gene SNP results in increased susceptibility to Beryllium; HLA-DPB1 protein mutant form results in increased susceptibility to Beryllium
CTD PMID:11551429 PMID:15273960 PMID:17956852 NCBI chr20:4,775,598...4,779,590
Ensembl chr20:4,774,650...4,780,618
JBrowse link
G Tnf tumor necrosis factor increases expression
increases response to substance
increases secretion
ISO Beryllium results in increased expression of TNF mRNA
TNF promoter polymorphism results in increased susceptibility to Beryllium
Beryllium results in increased secretion of TNF protein
CTD PMID:8629860 PMID:12449171 PMID:15127972 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
beryllium sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl4 acyl-CoA synthetase long-chain family member 4 multiple interactions
increases expression
ISO [sodium bisulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [beryllium sulfate results in increased expression of ACSL4 mRNA]; Deferoxamine inhibits the reaction [beryllium sulfate results in increased expression of ACSL4 mRNA]; NCOA4 protein affects the reaction [beryllium sulfate results in increased expression of ACSL4 mRNA] CTD PMID:36843388 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression ISO beryllium sulfate results in increased expression of ACTA2 mRNA CTD PMID:16314022 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Amot angiomotin decreases expression ISO beryllium sulfate results in decreased expression of AMOT mRNA CTD PMID:35679967 NCBI chr  X:108,982,399...109,041,265
Ensembl chr  X:108,984,022...109,041,272
JBrowse link
G Anxa5 annexin A5 increases expression ISO beryllium sulfate results in increased expression of ANXA5 mRNA CTD PMID:16314022 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Arhgap26 Rho GTPase activating protein 26 increases expression
decreases expression
ISO beryllium sulfate results in increased expression of ARHGAP26 mRNA
beryllium sulfate results in decreased expression of ARHGAP26 mRNA
CTD PMID:35679967 NCBI chr18:30,835,806...31,237,945
Ensembl chr18:30,838,671...31,235,194
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
increases secretion
ISO beryllium sulfate promotes the reaction [RUNX1 protein binds to CCL3 promoter]
beryllium sulfate results in increased secretion of CCL3 mRNA
CTD PMID:16314022 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases secretion ISO beryllium sulfate results in increased secretion of CCL4 mRNA CTD PMID:16314022 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO beryllium sulfate results in increased expression of CCL5 mRNA CTD PMID:16314022 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccnt1 cyclin T1 increases expression ISO beryllium sulfate results in increased expression of CCNT1 mRNA CTD PMID:35679967 NCBI chr 7:129,687,146...129,718,080
Ensembl chr 7:129,691,209...129,717,871
JBrowse link
G Cd44 CD44 molecule increases expression ISO beryllium sulfate results in increased expression of CD44 mRNA CTD PMID:16314022 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd86 CD86 molecule increases expression ISO beryllium sulfate results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO beryllium sulfate promotes the reaction [TP53 protein binds to CDKN1A promoter]
beryllium sulfate results in increased expression of CDKN1A mRNA; beryllium sulfate results in increased expression of CDKN1A protein
CTD PMID:17395767 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression ISO beryllium sulfate results in increased expression of CDKN2A mRNA; beryllium sulfate results in increased expression of CDKN2A protein CTD PMID:17395767 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO [beryllium sulfate co-treated with IFNG protein] results in increased expression of CREB1 protein CTD PMID:10755711 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Cryaa crystallin, alpha A decreases expression ISO beryllium sulfate results in decreased expression of CRYAA mRNA CTD PMID:35679967 NCBI chr20:9,783,605...9,787,351
Ensembl chr20:9,783,605...9,787,349
JBrowse link
G Ctsl cathepsin L increases expression ISO beryllium sulfate results in increased expression of CTSL mRNA CTD PMID:16314022 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
JBrowse link
G Cul9 cullin 9 increases expression
decreases expression
ISO beryllium sulfate results in increased expression of CUL9 mRNA
beryllium sulfate results in decreased expression of CUL9 mRNA
CTD PMID:35679967 NCBI chr 9:14,435,948...14,479,552
Ensembl chr 9:14,436,111...14,479,548
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases secretion ISO beryllium sulfate results in increased secretion of CXCL1 mRNA CTD PMID:16314022 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases secretion ISO beryllium sulfate results in increased secretion of CXCL1 mRNA CTD PMID:16314022 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Ddhd2 DDHD domain containing 2 increases expression ISO beryllium sulfate results in increased expression of DDHD2 mRNA CTD PMID:35679967 NCBI chr16:66,319,469...66,349,025
Ensembl chr16:66,319,466...66,349,023
JBrowse link
G Egr2 early growth response 2 increases expression ISO beryllium sulfate results in increased expression of EGR2 mRNA CTD PMID:16314022 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO beryllium sulfate results in increased expression of FOS mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]; Dactinomycin inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]; Ro 31-8220 inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]
CTD PMID:11568973 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions
decreases expression
ISO [sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [beryllium sulfate results in decreased expression of FTH1 mRNA]; [sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [beryllium sulfate results in decreased expression of FTH1 protein]; Deferoxamine inhibits the reaction [beryllium sulfate results in decreased expression of FTH1 mRNA]; Deferoxamine inhibits the reaction [beryllium sulfate results in decreased expression of FTH1 protein]; NCOA4 protein affects the reaction [beryllium sulfate results in decreased expression of FTH1 mRNA]; NCOA4 protein affects the reaction [beryllium sulfate results in decreased expression of FTH1 protein]
beryllium sulfate results in decreased expression of FTH1 mRNA; beryllium sulfate results in decreased expression of FTH1 protein
CTD PMID:36843388 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions
decreases expression
ISO [sodium bisulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [beryllium sulfate results in decreased expression of GPX4 mRNA]; Deferoxamine inhibits the reaction [beryllium sulfate results in decreased expression of GPX4 mRNA]; NCOA4 protein affects the reaction [beryllium sulfate results in decreased expression of GPX4 mRNA] CTD PMID:36843388 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 increases expression ISO beryllium sulfate results in increased expression of HNRNPA1 mRNA CTD PMID:16314022 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases secretion
increases expression
ISO 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [beryllium sulfate results in increased expression of ICAM1 mRNA]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [beryllium sulfate results in increased secretion of ICAM1 protein]; Dimethyl Sulfoxide inhibits the reaction [beryllium sulfate results in increased secretion of ICAM1 protein]
beryllium sulfate results in increased expression of ICAM1 mRNA; beryllium sulfate results in increased expression of ICAM1 protein
CTD PMID:18539414 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
ISO beryllium sulfate results in increased expression of IFNG protein
[beryllium sulfate co-treated with IFNG protein] results in increased expression of CREB1 protein; [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUN protein; [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUNB protein; [beryllium sulfate co-treated with IFNG protein] results in increased expression of NFKB1 protein; beryllium sulfate promotes the reaction [IFNG protein results in increased expression of TNF protein]
CTD PMID:10755710 PMID:10755711 PMID:20974702 PMID:33197057 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il10 interleukin 10 increases expression ISO beryllium sulfate results in increased expression of IL10 protein CTD PMID:33197057 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il18 interleukin 18 increases expression ISO beryllium sulfate results in increased expression of IL18 mRNA; beryllium sulfate results in increased expression of IL18 protein CTD PMID:16100009 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il2 interleukin 2 increases expression ISO beryllium sulfate results in increased expression of IL2 mRNA CTD PMID:9328138 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il5 interleukin 5 increases expression ISO beryllium sulfate results in increased expression of IL5 mRNA CTD PMID:9328138 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il6 interleukin 6 increases expression ISO beryllium sulfate results in increased expression of IL6 mRNA CTD PMID:9328138 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itgb3 integrin subunit beta 3 increases expression ISO beryllium sulfate results in increased expression of ITGB3 mRNA CTD PMID:16314022 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA]; [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUN protein; Dactinomycin inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA]; Ro 31-8220 inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA] CTD PMID:10755711 PMID:11568973 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUNB protein CTD PMID:10755711 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Krt4 keratin 4 decreases expression ISO beryllium sulfate results in decreased expression of KRT4 mRNA CTD PMID:35679967 NCBI chr 7:133,046,067...133,052,027
Ensembl chr 7:133,046,515...133,052,019
JBrowse link
G Mfsd14b major facilitator superfamily domain containing 14B decreases expression ISO beryllium sulfate results in decreased expression of MFSD14B mRNA CTD PMID:35679967 NCBI chr17:77,895...130,837
Ensembl chr17:77,840...130,839
JBrowse link
G Mir1306 microRNA 1306 increases expression ISO beryllium sulfate results in increased expression of MIR1306 mRNA CTD PMID:33197057 NCBI chr11:82,709,651...82,709,723
Ensembl chr11:82,709,637...82,709,719
JBrowse link
G Mir150 microRNA 150 increases expression ISO beryllium sulfate results in increased expression of MIR150 mRNA CTD PMID:33197057 NCBI chr 1:95,605,024...95,605,108
Ensembl chr 1:95,605,024...95,605,108
JBrowse link
G Mir193b microRNA 193b increases expression ISO beryllium sulfate results in increased expression of MIR193B mRNA CTD PMID:33197057 NCBI chr10:1,317,742...1,317,824
Ensembl chr10:1,317,742...1,317,824
JBrowse link
G Mir23b microRNA 23b decreases expression ISO beryllium sulfate results in decreased expression of MIR23B mRNA CTD PMID:33197057 NCBI chr17:1,813,667...1,813,763
Ensembl chr17:1,813,667...1,813,763
JBrowse link
G Mir324 microRNA 324 increases expression ISO beryllium sulfate results in increased expression of MIR324 mRNA CTD PMID:33197057 NCBI chr10:54,734,680...54,734,762
Ensembl chr10:54,734,678...54,734,766
JBrowse link
G Mir363 microRNA 363 increases expression ISO beryllium sulfate results in increased expression of MIR363 mRNA CTD PMID:33197057 NCBI chr  X:132,421,791...132,421,877
Ensembl chr  X:132,421,791...132,421,877
JBrowse link
G Mir484 microRNA 484 decreases expression ISO beryllium sulfate results in decreased expression of MIR484 mRNA CTD PMID:33197057 NCBI chr10:887,684...887,760
Ensembl chr10:887,684...887,760
JBrowse link
G Mir504 microRNA 504 increases expression ISO beryllium sulfate results in increased expression of MIR504 mRNA CTD PMID:33197057 NCBI chr  X:137,318,540...137,318,616
Ensembl chr  X:137,318,540...137,318,616
JBrowse link
G Mir877 microRNA 877 increases expression ISO beryllium sulfate results in increased expression of MIR877 mRNA CTD PMID:33197057 NCBI chr20:2,811,476...2,811,560
Ensembl chr20:2,811,476...2,811,560
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression EXP beryllium sulfate results in increased expression of MYC protein CTD PMID:2009323 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Ncoa4 nuclear receptor coactivator 4 multiple interactions
increases expression
ISO [sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [beryllium sulfate results in increased expression of NCOA4 mRNA]; [sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [beryllium sulfate results in increased expression of NCOA4 protein]; Deferoxamine inhibits the reaction [beryllium sulfate results in increased expression of NCOA4 mRNA]; Deferoxamine inhibits the reaction [beryllium sulfate results in increased expression of NCOA4 protein]; NCOA4 protein affects the reaction [beryllium sulfate results in decreased expression of FTH1 mRNA]; NCOA4 protein affects the reaction [beryllium sulfate results in decreased expression of FTH1 protein]; NCOA4 protein affects the reaction [beryllium sulfate results in decreased expression of GPX4 mRNA]; NCOA4 protein affects the reaction [beryllium sulfate results in decreased expression of SLC7A11 mRNA]; NCOA4 protein affects the reaction [beryllium sulfate results in increased expression of ACSL4 mRNA]; NCOA4 protein affects the reaction [beryllium sulfate results in increased expression of NCOA4 mRNA]; NCOA4 protein affects the reaction [beryllium sulfate results in increased expression of NCOA4 protein]; NCOA4 protein affects the reaction [beryllium sulfate results in increased expression of PTGS2 mRNA]
beryllium sulfate results in increased expression of NCOA4 mRNA; beryllium sulfate results in increased expression of NCOA4 protein
CTD PMID:36843388 NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,366,542...7,409,641
Ensembl chr16:7,366,542...7,409,641
JBrowse link
G Nedd8 NEDD8 ubiquitin like modifier increases expression ISO beryllium sulfate results in increased expression of NEDD8 mRNA CTD PMID:16314022 NCBI chr15:29,153,556...29,165,575
Ensembl chr15:29,153,556...29,166,160
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO [beryllium sulfate co-treated with IFNG protein] results in increased expression of NFKB1 protein CTD PMID:10755711 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression ISO beryllium sulfate results in increased expression of NOS2 protein CTD PMID:33197057 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nova1 NOVA alternative splicing regulator 1 increases expression ISO beryllium sulfate results in increased expression of NOVA1 mRNA CTD PMID:16314022 NCBI chr 6:63,780,105...63,905,567
Ensembl chr 6:63,783,489...63,906,289
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 decreases expression ISO beryllium sulfate results in decreased expression of PDPK1 mRNA CTD PMID:35679967 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
JBrowse link
G Phf19 PHD finger protein 19 decreases expression ISO beryllium sulfate results in decreased expression of PHF19 mRNA CTD PMID:35679967 NCBI chr 3:18,175,281...18,197,289
Ensembl chr 3:18,175,282...18,196,405
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions
ISO beryllium sulfate results in increased expression of PTGS2 mRNA; beryllium sulfate results in increased expression of PTGS2 protein
[sodium bisulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [beryllium sulfate results in increased expression of PTGS2 mRNA]; Deferoxamine inhibits the reaction [beryllium sulfate results in increased expression of PTGS2 mRNA]; NCOA4 protein affects the reaction [beryllium sulfate results in increased expression of PTGS2 mRNA]
CTD PMID:33197057 PMID:36843388 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rhoa ras homolog family member A increases expression ISO beryllium sulfate results in increased expression of RHOA mRNA CTD PMID:16314022 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rpl22 ribosomal protein L22 increases expression ISO beryllium sulfate results in increased expression of RPL22 mRNA CTD PMID:16314022 NCBI chr 5:162,835,241...162,843,394
Ensembl chr 5:162,833,740...162,843,368
Ensembl chr 7:162,833,740...162,843,368
Ensembl chr 4:162,833,740...162,843,368
JBrowse link
G Rpl30 ribosomal protein L30 increases expression ISO beryllium sulfate results in increased expression of RPL30 mRNA CTD PMID:16314022 NCBI chr 7:65,648,266...65,651,401
Ensembl chr 7:65,645,991...65,651,363
Ensembl chr10:65,645,991...65,651,363
Ensembl chr10:65,645,991...65,651,363
JBrowse link
G Rpl37a ribosomal protein L37A increases expression ISO beryllium sulfate results in increased expression of RPL37A mRNA CTD PMID:16314022 NCBI chr 9:74,298,843...74,300,926 JBrowse link
G Rps7 ribosomal protein S7 increases expression ISO beryllium sulfate results in increased expression of RPS7 mRNA CTD PMID:16314022 NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145
JBrowse link
G RT1-CE16 RT1 class I, locus CE16 increases expression ISO beryllium sulfate results in increased expression of HLA-A mRNA CTD PMID:16314022 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 increases response to substance
increases expression
ISO HLA-DRB1 protein mutant form results in increased susceptibility to beryllium sulfate
beryllium sulfate results in increased expression of HLA-DRB1 mRNA
CTD PMID:16272364 PMID:16314022 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G RT1-Hb-ps1 RT1 class II, locus Hb, pseudogene 1 affects binding ISO beryllium sulfate binds to HLA-DPB1 protein CTD PMID:11423174 NCBI chr20:4,775,598...4,779,590
Ensembl chr20:4,774,650...4,780,618
JBrowse link
G Runx1 RUNX family transcription factor 1 multiple interactions ISO beryllium sulfate promotes the reaction [RUNX1 protein binds to CCL3 promoter] CTD PMID:16314022 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542
JBrowse link
G Serpinb2 serpin family B member 2 increases expression ISO beryllium sulfate results in increased expression of SERPINB2 mRNA CTD PMID:16314022 NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408
JBrowse link
G Sftpd surfactant protein D increases expression ISO beryllium sulfate results in increased expression of SFTPD mRNA CTD PMID:16314022 NCBI chr16:17,046,491...17,058,968
Ensembl chr16:17,046,483...17,059,927
JBrowse link
G Slc7a11 solute carrier family 7 member 11 multiple interactions
decreases expression
ISO [sodium bisulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [beryllium sulfate results in decreased expression of SLC7A11 mRNA]; Deferoxamine inhibits the reaction [beryllium sulfate results in decreased expression of SLC7A11 mRNA]; NCOA4 protein affects the reaction [beryllium sulfate results in decreased expression of SLC7A11 mRNA] CTD PMID:36843388 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Tat tyrosine aminotransferase multiple interactions EXP beryllium sulfate inhibits the reaction [Hydrocortisone results in increased expression of TAT protein] CTD PMID:6120038 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
JBrowse link
G Thsd7a thrombospondin type 1 domain containing 7A decreases expression
increases expression
ISO beryllium sulfate results in decreased expression of THSD7A mRNA
beryllium sulfate results in increased expression of THSD7A mRNA
CTD PMID:35679967 NCBI chr 4:40,461,124...40,899,345
Ensembl chr 4:40,460,814...40,899,583
JBrowse link
G Tmsb4x thymosin beta 4, X-linked increases expression ISO beryllium sulfate results in increased expression of TMSB4X mRNA CTD PMID:16314022 NCBI chr  X:27,144,666...27,146,667
Ensembl chr  X:27,128,610...27,146,667
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO beryllium sulfate results in increased expression of TNF mRNA; beryllium sulfate results in increased expression of TNF protein
beryllium sulfate promotes the reaction [IFNG protein results in increased expression of TNF protein]
CTD PMID:10755710 PMID:10755711 PMID:33197057 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
ISO beryllium sulfate promotes the reaction [TP53 protein binds to CDKN1A promoter]
beryllium sulfate results in increased expression of TP53 protein
CTD PMID:17395767 PMID:20974702 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Wnt4 Wnt family member 4 increases expression ISO beryllium sulfate results in increased expression of WNT4 mRNA CTD PMID:16314022 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859
JBrowse link
G Zfp77 zinc finger protein 77 increases expression ISO beryllium sulfate results in increased expression of ZNF77 mRNA CTD PMID:16314022 NCBI chr 7:7,269,879...7,316,286
Ensembl chr 7:7,269,927...7,286,051
JBrowse link
beryllium(0) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions EXP [Beryllium results in increased methylation of CDKN2A promoter] which results in decreased expression of CDKN2A mRNA CTD PMID:11872642 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Esr1 estrogen receptor 1 increases methylation EXP Beryllium results in increased methylation of ESR1 gene CTD PMID:11872642 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Hras HRas proto-oncogene, GTPase increases mutagenesis EXP Beryllium results in increased mutagenesis of HRAS gene CTD PMID:7545909 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Il1b interleukin 1 beta increases expression
affects expression
ISO Beryllium results in increased expression of IL1B mRNA
Beryllium affects the expression of IL1B mRNA
CTD PMID:8473757 PMID:8629860 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G RT1-Hb-ps1 RT1 class II, locus Hb, pseudogene 1 increases response to substance
affects binding
ISO HLA-DPB1 gene polymorphism results in increased susceptibility to Beryllium; HLA-DPB1 gene SNP results in increased susceptibility to Beryllium; HLA-DPB1 protein mutant form results in increased susceptibility to Beryllium
HLA-DPB1 protein mutant form binds to Beryllium
CTD PMID:11551429 PMID:15273960 PMID:17956852 NCBI chr20:4,775,598...4,779,590
Ensembl chr20:4,774,650...4,780,618
JBrowse link
G Tnf tumor necrosis factor increases response to substance
increases secretion
increases expression
ISO TNF promoter polymorphism results in increased susceptibility to Beryllium
Beryllium results in increased secretion of TNF protein
Beryllium results in increased expression of TNF mRNA
CTD PMID:8629860 PMID:12449171 PMID:15127972 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
calcium atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions ISO Calcium deficiency inhibits the reaction [ABCB11 protein results in increased export of Taurocholic Acid] CTD PMID:25862123 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO Calcium deficiency inhibits the reaction [ABCB1 protein results in increased export of Xanthenes]; Calcium inhibits the reaction [Magnesium results in increased activity of ABCB1 protein] CTD PMID:2900677 PMID:25862123 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO Calcium deficiency inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein] CTD PMID:25862123 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Aco2 aconitase 2 increases activity
multiple interactions
ISO Calcium results in increased activity of ACO2 protein
[Calcium results in increased activity of ACO2 protein] which results in increased reduction of thiazolyl blue; [Nicardipine results in decreased uptake of Calcium] which results in decreased activity of ACO2 protein
CTD PMID:12548706 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Actb actin, beta multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of ACTB mRNA CTD PMID:15913539 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Adcy5 adenylate cyclase 5 decreases activity
increases response to substance
ISO Calcium results in decreased activity of ADCY5 protein
ADCY5 protein results in increased susceptibility to Calcium
CTD PMID:12065575 PMID:12869393 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974
JBrowse link
G Adcy9 adenylate cyclase 9 multiple interactions ISO Calcium inhibits the reaction [Miconazole results in increased activity of ADCY9 protein]; Tacrolimus inhibits the reaction [Calcium inhibits the reaction [Miconazole results in increased activity of ADCY9 protein]] CTD PMID:30607468 NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 increases abundance
affects abundance
multiple interactions
EXP ADCYAP1 protein results in increased abundance of Calcium
ADCYAP1 protein affects the abundance of Calcium
Calcium affects the reaction [ADCYAP1 protein results in increased expression of SELENOT mRNA]; SELENOT protein affects the reaction [ADCYAP1 protein results in increased abundance of Calcium]
CTD PMID:18198219 PMID:21039959 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773
JBrowse link
G Adgrl1 adhesion G protein-coupled receptor L1 multiple interactions EXP [alpha-latrotoxin binds to ADGRL1 protein] which results in increased uptake of Calcium; [black widow spider venom binds to ADGRL1 protein] which results in increased uptake of Calcium CTD PMID:10026162 NCBI chr19:24,202,405...24,244,137
Ensembl chr19:24,204,360...24,244,139
JBrowse link
G Adgrl2 adhesion G protein-coupled receptor L2 multiple interactions EXP [alpha-latrotoxin binds to ADGRL2 protein] which results in increased uptake of Calcium; [black widow spider venom binds to ADGRL2 protein] which results in increased uptake of Calcium CTD PMID:10026162 NCBI chr 2:237,696,055...238,327,141
Ensembl chr 2:237,696,056...238,327,141
JBrowse link
G Adm adrenomedullin decreases expression ISO Calcium results in decreased expression of ADM mRNA CTD PMID:20682585 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Adra1a adrenoceptor alpha 1A multiple interactions
affects transport
EXP
ISO
[Epinephrine binds to and results in increased activity of ADRA1A protein] which results in increased transport of Calcium; [Phenylephrine binds to and results in increased activity of ADRA1A protein] which results in increased transport of Calcium; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of EIF4EBP1 protein]; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of MTOR protein]; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of RPS6KB1 protein]
5-methylurapidil inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; [A 61603 results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Epinephrine binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Oxymetazoline binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]
ADRA1A protein affects the transport of Calcium
CTD PMID:12935885 PMID:15306222 PMID:15639650 PMID:15672411 PMID:16498073 More... NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
JBrowse link
G Adra1b adrenoceptor alpha 1B multiple interactions ISO [Epinephrine binds to and results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; [Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium] CTD PMID:15306222 PMID:16498073 PMID:20030735 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
JBrowse link
G Adra1d adrenoceptor alpha 1D multiple interactions ISO [Epinephrine binds to and results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; [Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium] CTD PMID:15306222 PMID:20030735 NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354
JBrowse link
G Adra2a adrenoceptor alpha 2A multiple interactions ISO [Epinephrine binds to and results in increased activity of ADRA2A protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA2A protein] which results in increased abundance of Calcium CTD PMID:20030735 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
JBrowse link
G Adra2b adrenoceptor alpha 2B multiple interactions ISO [Epinephrine binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; [Oxymetazoline binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; [xylometazoline binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium CTD PMID:20030735 NCBI chr 3:114,585,174...114,589,220
Ensembl chr 3:114,585,169...114,589,355
JBrowse link
G Adra2c adrenoceptor alpha 2C multiple interactions ISO [Epinephrine binds to and results in increased activity of ADRA2C protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA2C protein] which results in increased abundance of Calcium CTD PMID:20030735 NCBI chr14:75,470,884...75,472,846
Ensembl chr14:75,471,143...75,472,846
JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions EXP
ISO
[Terbutaline binds to and results in increased activity of ADRB2 protein] which affects the abundance of Calcium
[Benzo(a)pyrene binds to ADRB2 protein] which results in increased transport of Calcium; ADRB2 protein promotes the reaction [Benzo(a)pyrene results in increased transport of Calcium]
CTD PMID:10372813 PMID:22167199 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Ago2 argonaute RISC catalytic component 2 multiple interactions EXP Calcium affects the reaction [PICK1 protein binds to AGO2 protein]; Calcium deficiency inhibits the reaction [Excitatory Amino Acid Agonists inhibits the reaction [PICK1 protein binds to AGO2 protein]] CTD PMID:28404816 NCBI chr 7:105,018,202...105,105,118
Ensembl chr 7:105,029,120...105,104,974
JBrowse link
G Agt angiotensinogen increases uptake
affects localization
multiple interactions
increases abundance
ISO
EXP
AGT protein results in increased uptake of Calcium
AGT protein affects the localization of Calcium
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [AGT protein affects the localization of Calcium]; bafilomycin A1 inhibits the reaction [AGT protein affects the localization of Calcium]; Heparin inhibits the reaction [AGT protein affects the localization of Calcium]; Losartan inhibits the reaction [AGT protein affects the localization of Calcium]; Saralasin inhibits the reaction [AGT protein affects the localization of Calcium]; Sirolimus inhibits the reaction [AGT protein affects the localization of Calcium]; xestospongin C inhibits the reaction [AGT protein affects the localization of Calcium]
[AGT protein results in increased abundance of Calcium] which results in increased abundance of Reactive Oxygen Species
Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]
benidipine inhibits the reaction [AGT protein results in increased uptake of Calcium]; Mibefradil inhibits the reaction [AGT protein results in increased uptake of Calcium]
CTD PMID:10660688 PMID:18331727 PMID:18854758 PMID:21613610 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr1a angiotensin II receptor, type 1a affects expression EXP Calcium affects the expression of AGTR1A mRNA CTD PMID:15913539 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Agtr1b angiotensin II receptor, type 1b multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of AGTR1B mRNA CTD PMID:15913539 NCBI chr 2:102,844,969...102,920,232
Ensembl chr 2:102,844,969...102,920,232
JBrowse link
G Akap1 A-kinase anchoring protein 1 affects expression EXP Calcium affects the expression of AKAP1 mRNA CTD PMID:15913539 NCBI chr10:73,621,021...73,654,123
Ensembl chr10:73,621,883...73,653,896
JBrowse link
G Akap11 A-kinase anchoring protein 11 affects expression EXP Calcium affects the expression of AKAP11 mRNA CTD PMID:15913539 NCBI chr15:53,911,635...53,956,138
Ensembl chr15:53,911,657...53,941,605
JBrowse link
G Akt1 AKT serine/threonine kinase 1 affects abundance
affects expression
multiple interactions
affects response to substance
ISO
EXP
AKT1 protein affects the abundance of Calcium
Calcium affects the expression of AKT1 mRNA
[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein; Calcium affects the reaction [P2RY1 protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; CAMKK2 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; PDK1 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; PX-866 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; STO 609 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; W 7 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]
AKT1 protein affects the susceptibility to Calcium
CTD PMID:15913539 PMID:16094411 PMID:16236484 PMID:28634229 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions ISO ALDH2 protein inhibits the reaction [Ethanol affects the abundance of Calcium]
Calcium affects the reaction [ALDH2 gene SNP affects the abundance of Lead]
CTD PMID:17590987 PMID:28212632 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Alg2 ALG2, alpha-1,3/1,6-mannosyltransferase affects binding ISO Calcium binds to ALG2 protein CTD PMID:18997320 NCBI chr 5:61,768,738...61,773,297
Ensembl chr 5:61,768,740...61,773,297
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions ISO Calcium promotes the reaction [L 708714 binds to ALOX5 protein] CTD PMID:7577949 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Alpp alkaline phosphatase, placental affects binding ISO Calcium binds to ALPP protein CTD PMID:16815919 NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606
JBrowse link
G Ano1 anoctamin 1 multiple interactions
increases activity
ISO 9-phenanthrol inhibits the reaction [Calcium results in increased activity of ANO1 protein] CTD PMID:25573456 NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069
JBrowse link
G Anxa1 annexin A1 affects activity EXP Calcium affects the activity of ANXA1 protein CTD PMID:20655937 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Anxa5 annexin A5 multiple interactions ISO Calcium binds to and results in increased activity of ANXA5 protein; Calcium promotes the reaction [Phosphatidylserines binds to ANXA5 protein] CTD PMID:11578147 PMID:16076491 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Aoc1 amine oxidase, copper containing 1 affects binding ISO AOC1 protein binds to Calcium CTD PMID:12072962 NCBI chr 4:77,812,260...77,831,846
Ensembl chr 4:77,812,260...77,831,840
JBrowse link
G Apoe apolipoprotein E affects abundance
affects expression
ISO
EXP
APOE protein affects the abundance of Calcium
Calcium affects the expression of APOE mRNA
CTD PMID:15913539 PMID:17899169 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Apom apolipoprotein M affects expression EXP Calcium affects the expression of APOM mRNA CTD PMID:15913539 NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550
JBrowse link
G App amyloid beta precursor protein multiple interactions
increases uptake
affects abundance
ISO
EXP
2,4-Dinitrophenol affects the reaction [APP protein affects the abundance of Calcium]; 3-nitrophenol affects the reaction [APP protein affects the abundance of Calcium]; 4-anisidine affects the reaction [APP protein affects the abundance of Calcium]
APP protein modified form results in increased uptake of Calcium; APP protein results in increased uptake of Calcium
Calcium deficiency inhibits the reaction [APP protein modified form results in increased uptake of Calcium]; EDN3 protein inhibits the reaction [APP protein results in increased uptake of Calcium]; Flurbiprofen inhibits the reaction [APP protein results in increased uptake of Calcium]; Ibuprofen inhibits the reaction [APP protein results in increased uptake of Calcium]; Indomethacin inhibits the reaction [APP protein results in increased uptake of Calcium]; Nimodipine inhibits the reaction [APP protein results in increased uptake of Calcium]; Ruthenium Red inhibits the reaction [APP protein modified form results in increased uptake of Calcium]; Salicylates inhibits the reaction [APP protein results in increased uptake of Calcium]; sulindac sulfide inhibits the reaction [APP protein results in increased uptake of Calcium]
CTD PMID:12383957 PMID:18648507 PMID:18949129 PMID:24457011 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions ISO
EXP
ARRB2 protein affects the abundance of and affects the localization of Calcium
ARRB2 promotes the reaction [carvedilol results in increased uptake of Calcium]
CTD PMID:16210646 PMID:21078978 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of ATP1A1 mRNA CTD PMID:15913539 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 multiple interactions EXP Calcium affects the reaction [Ouabain results in increased expression of ATP1B1 mRNA] CTD PMID:11204457 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 affects transport
multiple interactions
EXP
ISO
ATP2A1 protein affects the transport of Calcium
[Phenols results in decreased activity of ATP2A1 protein] which results in decreased transport of Calcium
CTD PMID:11230109 PMID:18773882 NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 affects abundance
multiple interactions
affects transport
affects uptake
affects export
ISO
EXP
ATP2A2 protein affects the abundance of Calcium
Calcium promotes the reaction [Clioquinol results in decreased expression of ATP2A2 mRNA]; Calcium promotes the reaction [Clioquinol results in decreased expression of ATP2A2 protein]
ATP2A2 protein affects the transport of Calcium
[[Phenylephrine results in increased activity of SLC9A1 protein] which results in increased transport of Calcium] which results in increased expression of ATP2A2 protein; [Phenylephrine results in decreased expression of ATP2A2 protein] which results in decreased transport of Calcium; [Thapsigargin results in decreased activity of ATP2A2 protein] which results in decreased transport of Calcium
Calcium promotes the reaction [Clioquinol results in decreased expression of ATP2A2 mRNA]; Calcium promotes the reaction [Clioquinol results in decreased expression of ATP2A2 protein]; PPP3R1 gene mutant form inhibits the reaction [ATP2A2 protein affects the transport of Calcium]
ATP2A2 protein alternative form affects the uptake of Calcium
ATP2A2 protein alternative form affects the export of Calcium
CTD PMID:11679415 PMID:16236312 PMID:17287366 PMID:19244478 PMID:19328205 More... NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 multiple interactions
increases export
ISO caloxin 1b1 inhibits the reaction [ATP2B1 protein results in increased export of Calcium] CTD PMID:16452157 NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295
JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 increases export
multiple interactions
ISO ATP2B4 protein results in increased export of Calcium
caloxin 1b1 inhibits the reaction [ATP2B4 protein results in increased export of Calcium]
CTD PMID:16452157 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246
JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 multiple interactions EXP Calcium inhibits the reaction [ATP8B1 protein results in increased transport of Phosphatidylserines] CTD PMID:11584374 NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396
JBrowse link
G Avp arginine vasopressin multiple interactions
increases uptake
increases abundance
EXP 1-Butanol inhibits the reaction [AVP protein results in increased abundance of Calcium]; 2-(4-amylcinnamoyl)amino-4-chlorobenzoic acid inhibits the reaction [AVP protein results in increased abundance of Calcium]; [[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; [[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein; [AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium; [AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium; AVP protein results in increased import of and results in increased abundance of Calcium; Carvedilol inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium]; Chromium affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; Chromium affects the reaction [INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; chromium tripicolinate affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; chromium tripicolinate affects the reaction [INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; INS1 protein affects the reaction [Chromium affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; INS1 protein affects the reaction [chromium tripicolinate affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; Nicardipine inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium]; Nifedipine inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium] CTD PMID:9446840 PMID:11356622 PMID:11553362 PMID:14711191 PMID:21039959 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
JBrowse link
G Avpr1a arginine vasopressin receptor 1A multiple interactions EXP [[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; [[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein; [AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium; [NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium; Carbachol promotes the reaction [[NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium]; Nicardipine inhibits the reaction [[NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium]; Nicardipine inhibits the reaction [Carbachol promotes the reaction [[NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium]] CTD PMID:11553362 PMID:12646291 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215
JBrowse link
G Avpr2 arginine vasopressin receptor 2 affects expression EXP Calcium affects the expression of AVPR2 mRNA CTD PMID:15913539 NCBI chr  X:151,633,501...151,636,155
Ensembl chr  X:151,633,522...151,635,989
JBrowse link
G Axin1 axin 1 affects expression EXP Calcium affects the expression of AXIN1 mRNA CTD PMID:15913539 NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615
JBrowse link
G Bad BCL2-associated agonist of cell death affects expression EXP Calcium affects the expression of BAD mRNA CTD PMID:15913539 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bdkrb1 bradykinin receptor B1 multiple interactions ISO
EXP
2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [[kallidin, des-Arg(10)- results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]; [kallidin, des-Arg(10)- results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium; Sodium affects the reaction [[kallidin, des-Arg(10)- results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]
[kallidin, des-Arg(10)- binds to and results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium; bradykinin, Lys-Leu(8)-desArg(9)- inhibits the reaction [[kallidin, des-Arg(10)- binds to and results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]; Indomethacin inhibits the reaction [[kallidin, des-Arg(10)- binds to and results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]
CTD PMID:15703175 PMID:22554775 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
JBrowse link
G Bdkrb2 bradykinin receptor B2 multiple interactions ISO BDKRB2 protein affects the reaction [KNG1 protein affects the abundance of Calcium]
BDKRB2 protein affects the reaction [pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]]
CTD PMID:16473424 PMID:18054572 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
increases transport
ISO [Cadmium results in decreased transport of Calcium] inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein]; Calcium affects the reaction [Oxygen deficiency results in increased secretion of BDNF protein]
BDNF protein results in increased transport of Calcium
3,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]; 3,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide promotes the reaction [Tetrodotoxin inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]]; Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]; Tetrodotoxin inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]
CTD PMID:16553631 PMID:26095976 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Best1 bestrophin 1 increases activity
multiple interactions
ISO Calcium results in increased activity of BEST1 protein
[PAR-1-activating peptide results in increased abundance of Calcium] which results in increased activity of BEST1 protein
CTD PMID:19828819 PMID:25573456 NCBI chr 1:206,629,340...206,646,085
Ensembl chr 1:206,629,500...206,646,063
JBrowse link
G Bmp4 bone morphogenetic protein 4 affects expression
multiple interactions
EXP
ISO
Calcium affects the expression of BMP4 mRNA
[Calcium binds to MGP protein] which binds to and results in decreased activity of BMP4 protein; [Edetic Acid inhibits the reaction [Calcium binds to MGP protein]] inhibits the reaction [MGP protein binds to BMP4 protein]
CTD PMID:15913539 PMID:18369157 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Btk Bruton tyrosine kinase affects transport ISO BTK protein affects the transport of Calcium CTD PMID:12848851 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853
JBrowse link
G C5 complement C5 multiple interactions ISO [C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium; resveratrol inhibits the reaction [[C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium] CTD PMID:19284563 PMID:19346296 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A increases transport
multiple interactions
EXP CACNA1A protein results in increased transport of Calcium
Allethrins inhibits the reaction [CACNA1A protein results in increased transport of Calcium]
CTD PMID:14634047 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225
JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B multiple interactions
decreases uptake
increases transport
EXP decamethrin inhibits the reaction [CACNA1B protein results in increased transport of Calcium]; decamethrin promotes the reaction [CACNA1B gene mutant form results in increased transport of Calcium]
CACNA1B protein alternative form results in decreased uptake of Calcium
CTD PMID:18383452 PMID:22891239 NCBI chr 3:7,380,892...7,546,104
Ensembl chr 3:7,380,922...7,546,091
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C increases transport
multiple interactions
ISO
EXP
CACNA1C protein results in increased transport of Calcium
[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium; [CACNA2D4 protein binds to CACNA1C protein binds to CACNB3 protein] which results in increased transport of Calcium; CACNA2D4 protein promotes the reaction [[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium]
Allethrins inhibits the reaction [CACNA1C protein results in increased transport of Calcium]
CTD PMID:12181424 PMID:14634047 PMID:15299022 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D affects transport
multiple interactions
ISO
EXP
CACNA1D protein affects the transport of Calcium
CACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Calcium]
[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium; [CACNA1D protein results in increased uptake of Calcium] which affects the localization of SLC2A2 protein; [CACNA1D protein results in increased uptake of Calcium] which results in increased phosphorylation of MYL9 protein; CACNA2D1 protein promotes the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]; gabapentin affects the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]; SLC5A1 protein affects the reaction [CACNA1D protein results in increased uptake of Calcium]
CTD PMID:15357422 PMID:17272349 PMID:19796812 PMID:27798183 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215
JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E increases transport
multiple interactions
ISO
EXP
CACNA1E protein results in increased transport of Calcium
Calcium inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]
Cadmium inhibits the reaction [CACNA1E protein results in increased transport of Calcium]; Nickel inhibits the reaction [CACNA1E protein results in increased transport of Calcium]
CTD PMID:10627594 PMID:10669483 PMID:12663092 NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450
JBrowse link
G Cacna1f calcium voltage-gated channel subunit alpha1 F increases transport ISO CACNA1F protein results in increased transport of Calcium CTD PMID:14744918 NCBI chr  X:14,868,096...14,896,413
Ensembl chr  X:14,868,024...14,896,413
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G increases transport
multiple interactions
ISO
EXP
CACNA1G protein results in increased transport of Calcium
Allethrins inhibits the reaction [CACNA1G protein results in increased transport of Calcium]
CACNG2 protein affects the reaction [CACNA1G protein results in increased transport of Calcium]; CACNG4 protein affects the reaction [CACNA1G protein results in increased transport of Calcium]; CACNG5 protein affects the reaction [CACNA1G protein results in increased transport of Calcium]
CTD PMID:10734232 PMID:11073957 PMID:14634047 NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H increases transport
multiple interactions
ISO
EXP
CACNA1H protein results in increased transport of Calcium
Amiloride inhibits the reaction [CACNA1H protein results in increased transport of Calcium]; Nickel inhibits the reaction [CACNA1H protein results in increased transport of Calcium]
Amiloride inhibits the reaction [CACNA1H protein results in increased transport of Calcium]; Mibefradil inhibits the reaction [CACNA1H protein results in increased transport of Calcium]; Nickel inhibits the reaction [CACNA1H protein results in increased transport of Calcium]
CTD PMID:9930755 PMID:11073957 PMID:11897840 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I increases transport EXP CACNA1I protein results in increased transport of Calcium CTD PMID:11073957 NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 multiple interactions
increases transport
ISO
EXP
[gabapentin results in decreased activity of CACNA2D1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]; CACNA2D1 protein affects the reaction [Potassium Chloride results in increased transport of Calcium]
CACNA2D1 protein promotes the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]
CACNA2D1 protein results in increased transport of Calcium
CTD PMID:15474003 PMID:17442347 PMID:17881535 PMID:19796812 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969
JBrowse link
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 affects transport
multiple interactions
ISO CACNA2D2 protein affects the transport of Calcium
CACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Calcium]
CTD PMID:14660671 PMID:27798183 NCBI chr 8:108,072,208...108,203,516
Ensembl chr 8:108,072,454...108,203,173
JBrowse link
G Cacna2d4 calcium voltage-gated channel auxiliary subunit alpha2delta 4 multiple interactions ISO [CACNA2D4 protein binds to CACNA1C protein binds to CACNB3 protein] which results in increased transport of Calcium; CACNA2D4 protein promotes the reaction [[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium] CTD PMID:12181424 NCBI chr 4:152,408,588...152,521,478
Ensembl chr 4:152,408,657...152,521,268
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 multiple interactions ISO
EXP
[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium; [CACNA2D4 protein binds to CACNA1C protein binds to CACNB3 protein] which results in increased transport of Calcium; CACNA2D4 protein promotes the reaction [[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium]
[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium; CACNA2D1 protein promotes the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]; gabapentin affects the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]
CTD PMID:12181424 PMID:19796812 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074
JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 multiple interactions ISO CACNG2 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] CTD PMID:10734232 NCBI chr 7:109,572,838...109,698,516
Ensembl chr 7:109,574,459...109,697,227
JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 multiple interactions ISO CACNG4 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] CTD PMID:10734232 NCBI chr10:92,683,778...92,745,842
Ensembl chr10:92,683,761...92,746,126
JBrowse link
G Cacng5 calcium voltage-gated channel auxiliary subunit gamma 5 multiple interactions ISO CACNG5 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] CTD PMID:10734232 NCBI chr10:92,827,441...92,869,632
Ensembl chr10:92,829,196...92,869,614
JBrowse link
G Calb1 calbindin 1 affects expression EXP Calcium affects the expression of CALB1 mRNA CTD PMID:15913539 NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431
JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions
increases expression
ISO
EXP
rimabotulinumtoxinB inhibits the reaction [[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein]; rimabotulinumtoxinB inhibits the reaction [[Potassium co-treated with Calcium] results in increased secretion of CALCA protein]
Calcium promotes the reaction [Lipopolysaccharides results in increased expression of CALCA mRNA]
Calcium results in increased expression of CALCA mRNA
Calcium results in increased expression of CALCA protein
[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein; [KNG1 protein alternative form co-treated with Calcium] results in increased secretion of CALCA protein; [Potassium co-treated with Calcium] results in increased secretion of CALCA protein; [Sumatriptan results in increased abundance of Calcium] inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA]; botulinum toxin type D inhibits the reaction [[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein]; botulinum toxin type D inhibits the reaction [[Potassium co-treated with Calcium] results in increased secretion of CALCA protein]; Botulinum Toxins, Type A inhibits the reaction [[Potassium co-treated with Calcium] results in increased secretion of CALCA protein]; Calcium affects the reaction [Capsaicin inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Calcium affects the reaction [Capsaicin inhibits the reaction [mustard oil results in increased secretion of CALCA protein]]; Calcium affects the reaction [mustard oil inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Calcium deficiency inhibits the reaction [safranal results in increased secretion of CALCA protein]; Calcium inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA]
CTD PMID:2470235 PMID:12574409 PMID:17590514 PMID:17666428 PMID:20682585 More... NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Calm1 calmodulin 1 multiple interactions
affects binding
EXP
ISO
[Calcium binds to CALM1 protein] promotes the reaction [NOS1 protein results in increased chemical synthesis of Nitric Oxide]; [Calcium binds to CALM1 protein] which binds to and affects the folding of and results in increased activity of NOS1 protein; Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]; Calcium affects the reaction [CALM1 protein modified form binds to and affects the activity of RYR1 protein]; Calcium binds to and affects the folding of CALM1 protein
Calcium affects the folding of [CALM1 protein binds to RYR1 protein modified form]; Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]
CTD PMID:15381065 PMID:15628869 PMID:17098364 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calr calreticulin affects response to substance
multiple interactions
ISO CALR protein affects the susceptibility to Calcium
CALR protein promotes the reaction [KNG1 protein modified form results in increased abundance of Calcium]
CTD PMID:7961812 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta affects expression
multiple interactions
EXP
ISO
Calcium affects the expression of CAMK2D mRNA
[Ionomycin co-treated with Calcium co-treated with CAMK2D protein] results in increased activity of TRPM4 protein
CTD PMID:15913539 PMID:33392831 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 multiple interactions ISO CAMKK2 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein] CTD PMID:28634229 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279
JBrowse link
G Capn1 calpain 1 multiple interactions
increases cleavage
increases activity
ISO
EXP
[Caffeine co-treated with Alprazolam] promotes the reaction [Calcium results in increased activity of CAPN1 protein]; [Calcium co-treated with CAPN1 protein] results in increased degradation of TP73 protein modified form; [sodium arsenite results in increased abundance of Arsenic] promotes the reaction [[Calcium results in increased cleavage of CAPN1 protein] which results in increased degradation of CAPN1 protein]
calpain inhibitor III inhibits the reaction [Calcium results in increased activity of CAPN1 protein]
CTD PMID:19490937 PMID:21516125 PMID:21985864 PMID:31398423 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
JBrowse link
G Car4 carbonic anhydrase 4 affects expression EXP Calcium affects the expression of CA4 mRNA CTD PMID:15913539 NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501
JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO
[Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in increased expression of CASP3 mRNA]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in increased expression of CASP3 mRNA]; Calcium affects the reaction [sodium arsenite results in increased expression of CASP3 mRNA]
Calcium deficiency inhibits the reaction [Dasatinib results in increased activity of CASP3 protein]; Calcium deficiency inhibits the reaction [Ionomycin results in increased activity of CASP3 protein]
CTD PMID:24184500 PMID:29803841 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 multiple interactions EXP [Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in increased expression of CASP9 mRNA]]; Calcium affects the reaction [sodium arsenite results in increased expression of CASP9 mRNA] CTD PMID:24184500 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Casr calcium-sensing receptor increases phosphorylation
multiple interactions
increases uptake
increases activity
affects expression
decreases response to substance
increases response to substance
ISO
EXP
Calcium results in increased phosphorylation of CASR protein
[Aluminum binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Calcium binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Calcium binds to and results in increased activity of CASR protein] which results in increased abundance of Inositol Phosphates; [Gadolinium binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Magnesium binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Neomycin binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; Calcium binds to and results in increased activity of CASR protein; Gadolinium inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]
CASR protein results in increased uptake of Calcium
Calcium results in increased activity of CASR protein
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [CASR protein results in increased uptake of Calcium]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [CASR protein results in increased uptake of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]; 2-aminoethoxydiphenyl borate inhibits the reaction [CASR protein results in increased uptake of Calcium]; [2-quinoxaline-carboxamide-N-adamantan-1-yl binds to and results in decreased activity of CASR protein] inhibits the reaction [Nickel results in increased abundance of Calcium]; [Calcium binds to and results in increased activity of CASR protein] which results in increased uptake of Calcium; [CASR protein mutant form results in increased susceptibility to Calcium] which results in increased abundance of Inositol 1,4,5-Trisphosphate; [Spermine binds to and results in increased activity of CASR protein] which results in increased uptake of Calcium; bisindolylmaleimide I inhibits the reaction [NPS R-467 promotes the reaction [Calcium results in increased phosphorylation of CASR protein]]; Calcium Chloride promotes the reaction [Calcium results in increased phosphorylation of CASR protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of WNT5A protein]; CASR protein affects the reaction [Nickel results in increased abundance of Calcium]; CASR protein promotes the reaction [TRPC6 protein results in increased uptake of Calcium]; chelerythrine inhibits the reaction [CASR protein results in increased uptake of Calcium]; Flufenamic Acid promotes the reaction [CASR protein results in increased uptake of Calcium]; Lanthanum inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]; Lanthanum inhibits the reaction [CASR protein results in increased uptake of Calcium]; methyl-beta-cyclodextrin inhibits the reaction [CASR protein results in increased uptake of Calcium]; N-(2-chlorophenylpropyl)-1-(3-methoxyphenyl)ethylamine affects the reaction [CASR gene mutant form results in increased susceptibility to Calcium]; N-(2-chlorophenylpropyl)-1-(3-methoxyphenyl)ethylamine promotes the reaction [CASR protein results in increased susceptibility to Calcium]; NPS R-467 promotes the reaction [Calcium results in increased phosphorylation of CASR protein]; Pertussis Toxin inhibits the reaction [CASR protein results in increased uptake of Calcium]
Calcium affects the expression of CASR mRNA; Calcium affects the expression of CASR protein
CASR protein mutant form results in decreased susceptibility to Calcium
CASR gene mutant form results in increased susceptibility to Calcium; CASR protein mutant form results in increased susceptibility to Calcium
CTD PMID:7874174 PMID:9011580 PMID:10231437 PMID:11071898 PMID:11089548 More... NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811
JBrowse link
G Cat catalase multiple interactions ISO
EXP
CAT protein inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; CAT protein inhibits the reaction [Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]]
[Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in decreased activity of CAT protein]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in decreased activity of CAT protein]; [Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of CAT protein]; Calcium affects the reaction [sodium arsenite results in decreased activity of CAT protein]
CTD PMID:21127073 PMID:22534743 PMID:24184500 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav1 caveolin 1 affects transport ISO CAV1 protein affects the transport of Calcium CTD PMID:16428350 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cav3 caveolin 3 multiple interactions ISO CAV3 protein affects the reaction [Potassium Chloride results in increased uptake of Calcium] CTD PMID:21294223 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
JBrowse link
G Cbfb core-binding factor subunit beta affects expression EXP Calcium affects the expression of CBFB mRNA CTD PMID:15913539 NCBI chr19:33,049,162...33,092,752
Ensembl chr19:33,049,172...33,092,751
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases uptake ISO CCL11 protein results in increased uptake of Calcium CTD PMID:10984371 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccl12 C-C motif chemokine ligand 12 increases uptake ISO CCL13 protein results in increased uptake of Calcium CTD PMID:10984371 NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases abundance
multiple interactions
increases uptake
ISO CCL2 protein results in increased abundance of Calcium
montelukast inhibits the reaction [CCL2 protein results in increased abundance of Calcium]; Piperidines analog inhibits the reaction [CCL2 protein results in increased uptake of Calcium]; resveratrol inhibits the reaction [CCL2 protein affects the localization of Calcium]
CTD PMID:10843593 PMID:10984371 PMID:16212921 PMID:16771778 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO resveratrol inhibits the reaction [CCL3 protein affects the localization of Calcium] CTD PMID:16212921 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases uptake ISO CCL5 protein results in increased uptake of Calcium CTD PMID:10984371 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases uptake
multiple interactions
ISO CCL7 protein results in increased uptake of Calcium
Piperidines analog inhibits the reaction [CCL7 protein results in increased uptake of Calcium]
CTD PMID:10843593 PMID:10984371 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Ccnd1 cyclin D1 affects expression
increases expression
EXP
ISO
Calcium affects the expression of CCND1 mRNA
Calcium results in increased expression of CCND1 mRNA
CTD PMID:15913539 PMID:24658506 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccr10 C-C motif chemokine receptor 10 affects abundance ISO CCR10 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr10:86,108,551...86,110,988
Ensembl chr10:86,108,551...86,110,988
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 affects abundance ISO CCR4 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr 8:114,176,291...114,182,033
Ensembl chr 8:114,176,974...114,178,056
JBrowse link
G Ccr8 C-C motif chemokine receptor 8 affects abundance ISO CCR8 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr 8:119,826,332...119,828,292
Ensembl chr 8:119,826,568...119,827,629
JBrowse link
G Ccr9 C-C motif chemokine receptor 9 affects abundance ISO CCR9 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr 8:123,396,157...123,410,199
Ensembl chr 8:123,395,813...123,413,969
JBrowse link
G Cd28 Cd28 molecule multiple interactions
increases abundance
ISO 1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [CD28 protein results in increased abundance of Calcium]; 2-aminoethoxydiphenylborane inhibits the reaction [CD28 protein results in increased abundance of Calcium]; 5-diisopropoxyphosphoryl-5-methyl-1-pyrroline-N-oxide inhibits the reaction [CD28 protein results in increased abundance of Calcium]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [CD28 protein results in increased abundance of Calcium] CTD PMID:14607919 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
JBrowse link
G Cd38 CD38 molecule multiple interactions ISO CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]; CD38 protein inhibits the reaction [CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]] CTD PMID:20200208 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986
JBrowse link
G Cdc42 cell division cycle 42 multiple interactions ISO Calcium promotes the reaction [PAFAH1B1 protein binds to IQGAP1 protein binds to CDC42 protein] CTD PMID:16369480 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Cdc42bpb CDC42 binding protein kinase beta affects expression EXP Calcium affects the expression of CDC42BPB mRNA CTD PMID:15913539 NCBI chr 6:130,333,712...130,416,631
Ensembl chr 6:130,333,712...130,416,377
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 increases cleavage
multiple interactions
ISO Calcium results in increased cleavage of CDK5R1 protein
calpeptin inhibits the reaction [Calcium results in increased cleavage of CDK5R1 protein]
CTD PMID:18242949 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta affects expression EXP Calcium affects the expression of CEBPB mRNA CTD PMID:15913539 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cerk ceramide kinase multiple interactions ISO Calcium affects the reaction [CERK protein results in increased phosphorylation of Ceramides] CTD PMID:16269826 NCBI chr 7:117,225,855...117,269,436
Ensembl chr 7:117,225,855...117,268,759
JBrowse link
G Cfb complement factor B multiple interactions ISO CFD protein affects the reaction [[cobra venom factor co-treated with Magnesium co-treated with Calcium] results in increased cleavage of CFB protein] CTD PMID:11724962 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
JBrowse link
G Cfd complement factor D multiple interactions ISO CFD protein affects the reaction [[cobra venom factor co-treated with Magnesium co-treated with Calcium] results in increased cleavage of CFB protein] CTD PMID:11724962 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
JBrowse link
G Cfl1 cofilin 1 multiple interactions ISO [Capsaicin results in decreased phosphorylation of and results in increased activity of CFL1 protein] which results in increased import of Calcium CTD PMID:17303079 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 multiple interactions ISO
EXP
[Acetylcholine results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; [Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; [Pilocarpine results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; CHRM1 protein promotes the reaction [Methacholine Compounds results in increased abundance of Calcium]
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; 1-oleoyl-2-acetylglycerol promotes the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; [Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; Atropine inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Flufenamic Acid inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Gadolinium inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Lanthanum inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Pirenzepine inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Thapsigargin inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]
[[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; [[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein
CTD PMID:11527950 PMID:11553362 PMID:12456425 PMID:18316702 NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP [CHRNA4 protein co-treated with CHRNB2 protein mutant form] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein co-treated with CHRNB2 protein] affects the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein mutant form co-treated with CHRNB2 protein] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine] CTD PMID:12754307 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit multiple interactions ISO
EXP
[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium; [[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] which results in increased uptake of Calcium] inhibits the reaction [CHRNA7 protein results in decreased susceptibility to Okadaic Acid]; [Acetylcholine results in increased activity of CHRNA7 protein] which results in increased uptake of Calcium; [Bungarotoxins binds to and results in increased activity of CHRNA7 protein] which results in increased transport of Calcium; [methyllycaconitine binds to and results in increased activity of CHRNA7 protein] which results in increased transport of Calcium; [Nicotine results in increased activity of CHRNA7 protein] which results in increased transport of Calcium; [PNU-282987 binds to and results in increased activity of CHRNA7 protein] which results in increased uptake of Calcium; Bungarotoxins inhibits the reaction [[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium]; Mecamylamine inhibits the reaction [[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium]; methyllycaconitine inhibits the reaction [[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium]; methyllycaconitine promotes the reaction [[Nicotine results in increased activity of CHRNA7 protein] which results in increased transport of Calcium] CTD PMID:17709503 PMID:21051662 PMID:21715663 NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO
EXP
[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium; alpha-conotoxin MII inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium]; Calcium affects the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased susceptibility to Okadaic Acid]; Dihydro-beta-Erythroidine inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium]; Mecamylamine inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium]
[CHRNA4 protein co-treated with CHRNB2 protein mutant form] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein co-treated with CHRNB2 protein] affects the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein mutant form co-treated with CHRNB2 protein] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine]
CTD PMID:12754307 PMID:21715663 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 affects expression EXP Calcium affects the expression of CITED2 mRNA CTD PMID:15913539 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
JBrowse link
G Cln8 CLN8, transmembrane ER and ERGIC protein multiple interactions ISO CLN8 protein affects the reaction [[Ionomycin co-treated with Calcium] results in increased transport of D-Aspartic Acid]; CLN8 protein affects the reaction [[Potassium Chloride co-treated with Calcium] results in increased transport of D-Aspartic Acid] CTD PMID:22302580 NCBI chr16:74,749,662...74,759,553
Ensembl chr16:74,749,662...74,759,774
JBrowse link
G Cnnm4 cyclin and CBS domain divalent metal cation transport mediator 4 affects expression EXP Calcium affects the expression of CNNM4 mRNA CTD PMID:15913539 NCBI chr 9:38,711,726...38,750,942
Ensembl chr 9:38,711,710...38,750,942
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions EXP [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein] affects the reaction [Potassium Chloride results in increased transport of Calcium]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] affects the reaction [Potassium Chloride results in increased transport of Calcium]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium results in increased transport of Calcium]; Calcium affects the reaction [Potassium Chloride results in decreased expression of CNR1 mRNA]; Calcium affects the reaction [Potassium Chloride results in decreased expression of CNR1 protein]; CNR1 protein affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; CNR1 protein affects the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Pertussis Toxin inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]] CTD PMID:12421626 PMID:14973253 PMID:16412482 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions ISO CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]; Pertussis Toxin inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]]; SR 144528 inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]] CTD PMID:10617657 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain affects abundance ISO COL18A1 protein affects the abundance of Calcium CTD PMID:15296943 NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593
JBrowse link
G Col1a2 collagen type I alpha 2 chain affects abundance ISO COL1A2 protein affects the abundance of Calcium CTD PMID:10913914 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Cp ceruloplasmin affects binding
multiple interactions
ISO
EXP
Calcium binds to CP protein
[Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of CP protein]
CTD PMID:17242517 PMID:22534743 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects expression
multiple interactions
EXP Calcium affects the expression of CREB1 mRNA
[Estradiol results in increased import of Calcium] which results in increased activity of CREB1 protein; Calcium promotes the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased phosphorylation of CREB1 protein]; Calcium promotes the reaction [Dopamine results in increased phosphorylation of CREB1 protein]
CTD PMID:14622123 PMID:15802184 PMID:15913539 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 affects expression EXP Calcium affects the expression of CSNK1A1 mRNA CTD PMID:15913539 NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271