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Accession:CHEBI:222828 term browser browse the term
Definition:Amino acid amide formed from 2,6-dimethylaniline and N-ethylglycine components; an active metabolite of lidocaine, formed by oxidative deethylation. Used as an indicator of hepatic function.
Synonyms:exact_synonym: N-(2,6-dimethylphenyl)-N(2)-ethylglycinamide
 related_synonym: 2-Ethylamino-2',6'-acetoxylidide;   2-Ethylamino-2,6-acetoxylidine;   Ethylglycylxylidide;   Formula=C12H18N2O;   InChI=1S/C12H18N2O/c1-4-13-8-11(15)14-12-9(2)6-5-7-10(12)3/h5-7,13H,4,8H2,1-3H3,(H,14,15);   InChIKey=WRMRXPASUROZGT-UHFFFAOYSA-N;   Lidocaine N-de-ethylated metabolite;   N-(2,6-Dimethylphenyl)-2-(ethylamino)acetamide;   N-Ethylglycinexylidide;   SMILES=CCNCC(=O)Nc1c(C)cccc1C;   norlidocaine;   omega-(ethylamino)-2',6'-dimethylacetanilide
 xref: Beilstein:2417108 "Beilstein";   CAS:7728-40-7 "ChemIDplus";   CAS:7728-40-7 "KEGG COMPOUND";   CAS:7728-40-7 "NIST Chemistry WebBook";   HMDB:HMDB0060656;   KEGG:C16561
 xref_mesh: MESH:C001173
 xref: PMID:17296334 "Europe PMC";   PMID:22212047 "Europe PMC";   PMID:22452841 "Europe PMC";   PMID:22468031 "Europe PMC";   PMID:7071904 "Europe PMC";   PMID:9989796 "Europe PMC";   Reaxys:2417108 "Reaxys"

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monoethylglycinexylidide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ces1d carboxylesterase 1D JBrowse link 19 15,195,514 15,239,827 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19734
    role 19680
      biological role 19678
        biochemical role 19177
          metabolite 19147
            xenobiotic metabolite 13835
              human xenobiotic metabolite 13025
                drug metabolite 4394
                  monoethylglycinexylidide 1
                    monoethylglycinexylidide hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19734
    subatomic particle 19730
      composite particle 19730
        hadron 19730
          baryon 19730
            nucleon 19730
              atomic nucleus 19730
                atom 19730
                  main group element atom 19614
                    p-block element atom 19614
                      carbon group element atom 19506
                        carbon atom 19500
                          organic molecular entity 19500
                            organic group 18414
                              organic divalent group 18406
                                organodiyl group 18406
                                  carbonyl group 18295
                                    carbonyl compound 18295
                                      carboxylic acid 17963
                                        carboacyl group 17074
                                          univalent carboacyl group 17074
                                            carbamoyl group 16804
                                              carboxamide 16804
                                                amino acid amide 883
                                                  monoethylglycinexylidide 1
                                                    monoethylglycinexylidide hydrochloride 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.