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G
|
Abl1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of ABL1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of ABL1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ABL1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:35,377,391...35,480,846
|
|
G
|
Acox2
|
acyl-CoA oxidase 2
|
decreases expression
|
EXP
|
Methylnitronitrosoguanidine results in decreased expression of ACOX2 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr15:19,090,820...19,122,392
Ensembl chr15:19,090,926...19,122,392
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|
G
|
Adam10
|
ADAM metallopeptidase domain 10
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of ADAM10 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 8:80,226,862...80,358,728
Ensembl chr 8:80,226,674...80,361,600
|
|
G
|
Agt
|
angiotensinogen
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of AGT mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of AGT mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of AGT mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944
|
|
G
|
Aifm1
|
apoptosis inducing factor, mitochondria associated 1
|
multiple interactions increases localization
|
ISO
|
benzamide inhibits the reaction [Methylnitronitrosoguanidine results in increased localization of AIFM1 protein]; phenanthridone inhibits the reaction [Methylnitronitrosoguanidine results in increased localization of AIFM1 protein]
|
CTD |
PMID:15589979 |
|
NCBI chr X:132,528,107...132,567,237
Ensembl chr X:132,528,107...132,567,237
|
|
G
|
Akt1
|
AKT serine/threonine kinase 1
|
increases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of AKT1 mRNA corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of AKT1 mRNA]
|
CTD |
PMID:35103375 |
|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
|
|
G
|
Alb
|
albumin
|
decreases secretion
|
EXP
|
Methylnitronitrosoguanidine results in decreased secretion of ALB protein
|
CTD |
PMID:15772367 |
|
NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
|
|
G
|
Aldh1a1
|
aldehyde dehydrogenase 1 family, member A1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of ALDH1A1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of ALDH1A1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ALDH1A1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
|
|
G
|
Alpl
|
alkaline phosphatase, biomineralization associated
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of ALPL mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167
|
|
G
|
Ambp
|
alpha-1-microglobulin/bikunin precursor
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of AMBP mRNA
|
CTD |
PMID:12773770 |
|
NCBI chr 5:81,583,621...81,593,938
Ensembl chr 5:81,583,622...81,593,850
|
|
G
|
Anxa5
|
annexin A5
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of ANXA5 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 2:121,242,133...121,272,935
Ensembl chr 2:121,242,136...121,281,400
|
|
G
|
Apaf1
|
apoptotic peptidase activating factor 1
|
affects response to substance multiple interactions decreases expression
|
ISO
|
APAF1 protein affects the susceptibility to Methylnitronitrosoguanidine Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of APAF1 protein]
|
CTD |
PMID:16019050 PMID:20434464 |
|
NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772
|
|
G
|
Apc
|
APC regulator of WNT signaling pathway
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of APC mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr18:26,138,382...26,196,021
Ensembl chr18:26,102,679...26,197,022
|
|
G
|
App
|
amyloid beta precursor protein
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of APP mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of APP mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of APP mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
|
|
G
|
Araf
|
A-Raf proto-oncogene, serine/threonine kinase
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of ARAF mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr X:3,780,932...3,845,919
Ensembl chr X:3,780,932...3,792,611
|
|
G
|
Atm
|
ATM serine/threonine kinase
|
increases response to substance
|
ISO
|
ATM gene mutant form results in increased susceptibility to Methylnitronitrosoguanidine
|
CTD |
PMID:15010311 |
|
NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629
|
|
G
|
Atp1b3
|
ATPase Na+/K+ transporting subunit beta 3
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of ATP1B3 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 8:105,789,824...105,821,151
Ensembl chr 8:65,253,361...65,254,304 Ensembl chr 8:65,253,361...65,254,304
|
|
G
|
Atr
|
ATR serine/threonine kinase
|
multiple interactions
|
ISO
|
ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F1 protein]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F3 protein]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of TP53 protein]
|
CTD |
PMID:26921499 |
|
NCBI chr 8:105,306,299...105,403,742
Ensembl chr 8:105,306,305...105,403,718
|
|
G
|
Axl
|
Axl receptor tyrosine kinase
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of AXL mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 1:90,392,864...90,424,123
Ensembl chr 1:90,392,864...90,424,009
|
|
G
|
Bad
|
BCL2-associated agonist of cell death
|
decreases expression multiple interactions decreases phosphorylation
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of BAD mRNA Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAD mRNA] N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased phosphorylation of BAD protein]
|
CTD |
PMID:17828454 PMID:20434464 |
|
NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034
|
|
G
|
Bag1
|
BAG cochaperone 1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of BAG1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 5:60,864,476...60,877,059
Ensembl chr 5:60,864,476...60,878,161
|
|
G
|
Bak1
|
BCL2-antagonist/killer 1
|
multiple interactions
|
ISO
|
BAK1 protein results in increased susceptibility to [Methylnitronitrosoguanidine co-treated with veliparib]
|
CTD |
PMID:18376143 |
|
NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974
|
|
G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
multiple interactions decreases expression
|
EXP ISO
|
[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BAX protein; corilagin inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAX protein] BAX protein results in increased susceptibility to [Methylnitronitrosoguanidine co-treated with veliparib] Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAX mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAX protein] Methylnitronitrosoguanidine results in decreased expression of BAX mRNA; Methylnitronitrosoguanidine results in decreased expression of BAX protein
|
CTD |
PMID:16030430 PMID:18376143 PMID:20434464 PMID:35103375 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
|
|
G
|
Bcat2
|
branched chain amino acid transaminase 2
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of BCAT2 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 1:105,175,157...105,196,474
Ensembl chr 1:105,176,977...105,196,463
|
|
G
|
Bcl2
|
BCL2, apoptosis regulator
|
decreases expression multiple interactions increases expression
|
ISO EXP
|
Methylnitronitrosoguanidine results in decreased expression of BCL2 protein [Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein; [S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2 protein]; Lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; S-allylcysteine inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2 protein] Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2 protein] Methylnitronitrosoguanidine results in increased expression of BCL2 mRNA; Methylnitronitrosoguanidine results in increased expression of BCL2 protein weifuchun affects the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2 protein]
|
CTD |
PMID:16019050 PMID:16030430 PMID:20434464 PMID:35103375 PMID:36403744 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
|
|
G
|
Bcl2l1
|
Bcl2-like 1
|
multiple interactions increases expression
|
ISO
|
BCL2L1 protein results in decreased susceptibility to [Methylnitronitrosoguanidine co-treated with veliparib] Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2L1 mRNA]
|
CTD |
PMID:18376143 PMID:20434464 |
|
NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907 Ensembl chr 1:161,745,540...161,764,907
|
|
G
|
Bcl2l11
|
Bcl2-like 11
|
multiple interactions
|
EXP
|
[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BCL2L11 protein; S-allylcysteine inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BCL2L11 protein]
|
CTD |
PMID:16030430 |
|
NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695
|
|
G
|
Bdnf
|
brain-derived neurotrophic factor
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of BDNF mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657
|
|
G
|
Bgn
|
biglycan
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of BGN mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of BGN mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BGN mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr X:156,348,633...156,360,797
Ensembl chr X:156,348,615...156,360,799
|
|
G
|
Bid
|
BH3 interacting domain death agonist
|
multiple interactions decreases expression
|
ISO
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BID mRNA]
|
CTD |
PMID:20434464 |
|
NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275
|
|
G
|
Birc2
|
baculoviral IAP repeat-containing 2
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of BIRC2 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:13,253,706...13,271,911
|
|
G
|
Blvrb
|
biliverdin reductase B
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of BLVRB mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 1:91,866,258...91,883,921
Ensembl chr 1:91,866,258...91,884,225
|
|
G
|
Bmp4
|
bone morphogenetic protein 4
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of BMP4 mRNA
|
CTD |
PMID:12773770 |
|
NCBI chr15:22,098,191...22,113,145
Ensembl chr15:22,098,470...22,105,172
|
|
G
|
Brca1
|
BRCA1, DNA repair associated
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of BRCA1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763
|
|
G
|
Brca2
|
BRCA2, DNA repair associated
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of BRCA2 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr12:4,895,092...4,939,340
Ensembl chr12:4,895,447...4,936,194
|
|
G
|
Bsg
|
basigin
|
multiple interactions increases expression
|
EXP
|
corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BSG mRNA]
|
CTD |
PMID:35103375 |
|
NCBI chr 7:10,643,788...10,651,005
Ensembl chr 7:10,643,789...10,651,005
|
|
G
|
Btg2
|
BTG anti-proliferation factor 2
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of BTG2 protein
|
CTD |
PMID:24821435 |
|
NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690
|
|
G
|
C1qb
|
complement C1q B chain
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of C1QB mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 5:154,402,276...154,407,827
Ensembl chr 5:154,402,279...154,407,840
|
|
G
|
C1s
|
complement C1s
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of C1S mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 4:159,116,549...159,128,736
Ensembl chr 4:159,116,549...159,128,736
|
|
G
|
Calm1
|
calmodulin 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CALM1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CALM1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CALM1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 6:125,217,191...125,227,855
Ensembl chr 6:125,217,246...125,225,381
|
|
G
|
Casp3
|
caspase 3
|
increases activity multiple interactions decreases expression
|
ISO EXP
|
Methylnitronitrosoguanidine results in increased activity of CASP3 protein [Methylnitronitrosoguanidine co-treated with N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride] results in increased activity of CASP3 protein; [Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP3 protein; [S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP3 protein]; corilagin inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP3 protein] Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP3 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP3 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride promotes the reaction [Methylnitronitrosoguanidine results in increased activity of CASP3 protein] Methylnitronitrosoguanidine results in decreased expression of CASP3 mRNA; Methylnitronitrosoguanidine results in decreased expression of CASP3 protein
|
CTD |
PMID:15589979 PMID:16019050 PMID:16030430 PMID:17428624 PMID:20434464 PMID:24476502 PMID:35103375 More...
|
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
|
|
G
|
Casp4
|
caspase 4
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of CASP4 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:10,883,769...10,920,727
|
|
G
|
Casp8
|
caspase 8
|
multiple interactions
|
EXP
|
[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein; [S-allylcysteine co-treated with lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]; lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]; S-allylcysteine inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]
|
CTD |
PMID:16030430 |
|
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
|
|
G
|
Casp9
|
caspase 9
|
increases activity multiple interactions decreases expression
|
ISO EXP
|
Methylnitronitrosoguanidine results in increased activity of CASP9 protein Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP9 protein] corilagin inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP9 protein]
|
CTD |
PMID:15589979 PMID:16019050 PMID:20434464 PMID:35103375 |
|
Ensembl chr 5:159,391,188...159,409,648
|
|
G
|
Cat
|
catalase
|
multiple interactions decreases activity
|
EXP
|
corilagin inhibits the reaction [Methylnitronitrosoguanidine results in decreased activity of CAT protein]
|
CTD |
PMID:35103375 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
|
|
G
|
Cbx5
|
chromobox 5
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of CBX5 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 7:136,203,827...136,254,575
Ensembl chr 7:136,211,649...136,229,118
|
|
G
|
Ccna1
|
cyclin A1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of CCNA1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 2:141,383,352...141,428,205
Ensembl chr 2:141,382,468...141,393,300
|
|
G
|
Ccnb1
|
cyclin B1
|
multiple interactions increases expression decreases expression
|
EXP ISO
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CCNB1 mRNA] [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CCNB1 mRNA Methylnitronitrosoguanidine results in decreased expression of CCNB1 mRNA
|
CTD |
PMID:11516527 PMID:12135628 PMID:19851710 |
|
NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
|
|
G
|
Ccnd1
|
cyclin D1
|
multiple interactions increases expression
|
EXP ISO
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CCND1 mRNA] Methylnitronitrosoguanidine results in increased expression of CCND1 mRNA; Methylnitronitrosoguanidine results in increased expression of CCND1 protein [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CCND1 protein
|
CTD |
PMID:12135628 PMID:19851710 PMID:21628965 |
|
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
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|
G
|
Ccng1
|
cyclin G1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of CCNG1 mRNA
|
CTD |
PMID:11516527 |
|
NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766
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G
|
Ccnh
|
cyclin H
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of CCNH mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 2:17,570,449...17,591,078
Ensembl chr 2:17,570,263...17,614,860
|
|
G
|
Cct2
|
chaperonin containing TCP1 subunit 2
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CCT2 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 7:54,578,654...54,591,428
Ensembl chr 7:54,578,663...54,592,977
|
|
G
|
Cd14
|
CD14 molecule
|
increases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of CD14 protein weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CD14 protein]
|
CTD |
PMID:36403744 |
|
NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292
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|
G
|
Cd59b
|
CD59b molecule
|
increases mutagenesis
|
ISO
|
Methylnitronitrosoguanidine results in increased mutagenesis of CD59 protein
|
CTD |
PMID:17045307 |
|
NCBI chr 3:110,914,008...110,932,489
Ensembl chr 3:110,914,091...110,935,310
|
|
G
|
Cd9
|
CD9 molecule
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CD9 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CD9 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD9 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 4:159,942,553...159,975,463
Ensembl chr 4:159,942,560...159,975,444
|
|
G
|
Cdh1
|
cadherin 1
|
multiple interactions decreases expression
|
EXP ISO
|
geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 protein] Methylnitronitrosoguanidine results in decreased expression of CDH1 mRNA; Methylnitronitrosoguanidine results in decreased expression of CDH1 protein KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 mRNA]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 protein]]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 mRNA]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 protein] KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 mRNA]
|
CTD |
PMID:28428697 PMID:38184286 |
|
NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
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|
G
|
Cdh2
|
cadherin 2
|
increases expression multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of CDH2 mRNA KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of CDH2 mRNA] Methylnitronitrosoguanidine results in increased expression of CDH2 mRNA; Methylnitronitrosoguanidine results in increased expression of CDH2 protein KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CDH2 mRNA]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CDH2 protein]]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CDH2 mRNA]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CDH2 protein]
|
CTD |
PMID:38184286 |
|
NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288
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|
G
|
Cdh8
|
cadherin 8
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of CDH8 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr19:5,494,552...5,901,950
Ensembl chr19:5,500,221...5,902,627
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|
G
|
Cdk4
|
cyclin-dependent kinase 4
|
increases expression multiple interactions
|
EXP ISO
|
Methylnitronitrosoguanidine results in increased expression of CDK4 protein [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CDK4 protein weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CDK4 protein]
|
CTD |
PMID:12135628 PMID:21628965 PMID:36403744 |
|
NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163
|
|
G
|
Cdk5
|
cyclin-dependent kinase 5
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of CDK5 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 4:11,647,098...11,651,606
Ensembl chr 4:11,647,141...11,652,777
|
|
G
|
Cdkn1a
|
cyclin-dependent kinase inhibitor 1A
|
decreases expression multiple interactions
|
ISO EXP
|
Methylnitronitrosoguanidine results in decreased expression of CDKN1A mRNA Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDKN1A protein]
|
CTD |
PMID:12634122 PMID:19851710 |
|
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
|
|
G
|
Cdkn1b
|
cyclin-dependent kinase inhibitor 1B
|
decreases expression increases expression multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of CDKN1B mRNA Methylnitronitrosoguanidine results in increased expression of CDKN1B protein Cadmium Chloride inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CDKN1B protein]; Cadmium Chloride promotes the reaction [Methylnitronitrosoguanidine results in decreased expression of CDKN1B mRNA]
|
CTD |
PMID:11516527 PMID:12135628 |
|
NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498
|
|
G
|
Cep43
|
centrosomal protein 43
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of CEP43 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 1:55,080,983...55,111,509
Ensembl chr 1:55,082,712...55,111,509
|
|
G
|
Chek1
|
checkpoint kinase 1
|
multiple interactions
|
ISO
|
CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F3 protein]; CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]
|
CTD |
PMID:26921499 |
|
NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359
|
|
G
|
Chek2
|
checkpoint kinase 2
|
multiple interactions
|
ISO
|
CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F1 protein]; CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein]; CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of TP53 protein]
|
CTD |
PMID:26921499 |
|
NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667
|
|
G
|
Ckb
|
creatine kinase B
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of CKB mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 6:136,550,583...136,553,464
Ensembl chr 6:136,549,844...136,553,478
|
|
G
|
Clta
|
clathrin, light chain A
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CLTA mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CLTA mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CLTA mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 5:63,022,046...63,059,223
Ensembl chr 5:63,041,184...63,059,215
|
|
G
|
Col1a2
|
collagen type I alpha 2 chain
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of COL1A2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of COL1A2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL1A2 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995
|
|
G
|
Col6a1
|
collagen type VI alpha 1 chain
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of COL6A1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of COL6A1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL6A1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr20:11,905,690...11,924,111
Ensembl chr20:11,905,457...11,924,107
|
|
G
|
Col8a1
|
collagen type VIII alpha 1 chain
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of COL8A1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of COL8A1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL8A1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr11:56,245,998...56,378,586
Ensembl chr11:56,369,868...56,376,229
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|
G
|
Cox6a1
|
cytochrome c oxidase subunit 6A1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of COX6A1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr12:46,922,709...46,925,762
Ensembl chr12:46,912,648...46,925,768
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|
G
|
Cox8a
|
cytochrome c oxidase subunit 8A
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of COX8A mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 1:213,831,302...213,833,623
Ensembl chr 1:213,831,298...213,833,623
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|
G
|
Ctnnb1
|
catenin beta 1
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multiple interactions increases expression
|
EXP
|
geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CTNNB1 mRNA]
|
CTD |
PMID:28428697 |
|
NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
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|
G
|
Ctsb
|
cathepsin B
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of CTSB mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of CTSB mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CTSB mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478
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|
G
|
Ctsl
|
cathepsin L
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CTSL mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CTSL mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CTSL mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113
|
|
G
|
Cxcl12
|
C-X-C motif chemokine ligand 12
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CXCL12 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627
|
|
G
|
Cxcr4
|
C-X-C motif chemokine receptor 4
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of CXCR4 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459
|
|
G
|
Cyb561d2
|
cytochrome b561 family, member D2
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of CYB561D2 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 8:117,091,844...117,094,434
Ensembl chr 8:117,091,845...117,094,366
|
|
G
|
Cycs
|
cytochrome c, somatic
|
multiple interactions decreases expression
|
ISO
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CYCS mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CYCS protein] Methylnitronitrosoguanidine results in decreased expression of CYCS mRNA; Methylnitronitrosoguanidine results in decreased expression of CYCS protein
|
CTD |
PMID:20434464 |
|
NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816 Ensembl chr18:80,982,668...80,984,816
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|
G
|
Dab2
|
DAB adaptor protein 2
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of DAB2 mRNA
|
CTD |
PMID:12634122 PMID:12773770 |
|
NCBI chr 2:57,241,947...57,294,893
Ensembl chr 2:57,242,064...57,294,888
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|
G
|
Dcn
|
decorin
|
decreases expression
|
EXP
|
Methylnitronitrosoguanidine results in decreased expression of DCN mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:34,163,011...34,218,926
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|
G
|
Deaf1
|
DEAF1 transcription factor
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of DEAF1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 1:205,831,428...205,865,106
Ensembl chr 1:205,831,336...205,865,106
|
|
G
|
Dek
|
DEK proto-oncogene
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of DEK mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr17:17,786,989...17,809,096
Ensembl chr17:17,787,139...17,810,122
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|
G
|
Dlg1
|
discs large MAGUK scaffold protein 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of DLG1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of DLG1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of DLG1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr11:82,416,853...82,607,797
Ensembl chr11:82,416,853...82,607,797
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|
G
|
Dstn
|
destrin, actin depolymerizing factor
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of DSTN mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 3:151,737,711...151,764,752
Ensembl chr 3:151,737,849...151,764,769
|
|
G
|
Dut
|
deoxyuridine triphosphatase
|
affects localization increases secretion
|
ISO
|
Methylnitronitrosoguanidine affects the localization of DUT protein Methylnitronitrosoguanidine results in increased secretion of DUT protein
|
CTD |
PMID:21658424 |
|
NCBI chr 3:132,952,258...132,963,433
Ensembl chr 3:132,952,394...132,964,956
|
|
G
|
E2f1
|
E2F transcription factor 1
|
increases expression multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of E2F1 protein ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F1 protein]; CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F1 protein]; E2F1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B mRNA]; Methylnitronitrosoguanidine promotes the reaction [E2F1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [E2F1 protein results in increased expression of RRM2 mRNA]
|
CTD |
PMID:26921499 |
|
NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563
|
|
G
|
E2f3
|
E2F transcription factor 3
|
multiple interactions
|
ISO
|
[[Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein] which results in increased expression of RRM2 mRNA] inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]; [Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein] which results in increased expression of RRM2 mRNA; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F3 protein]; CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F3 protein]; CHIR-124 inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of E2F3 protein]; E2F3 protein inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B mRNA]; Methylnitronitrosoguanidine promotes the reaction [E2F3 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [E2F3 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein binds to RRM2 promoter]]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein results in increased expression of RRM2 mRNA]]
|
CTD |
PMID:26921499 |
|
NCBI chr17:34,810,355...34,887,725
Ensembl chr17:34,809,998...34,887,725
|
|
G
|
Egf
|
epidermal growth factor
|
affects activity multiple interactions
|
ISO
|
Methylnitronitrosoguanidine affects the activity of EGF protein Methylnitronitrosoguanidine inhibits the reaction [EGF protein results in increased activity of HRAS protein]; Methylnitronitrosoguanidine inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]
|
CTD |
PMID:15708576 |
|
NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
|
|
G
|
Egfr
|
epidermal growth factor receptor
|
affects localization multiple interactions
|
ISO
|
Methylnitronitrosoguanidine affects the localization of EGFR protein Methylnitronitrosoguanidine inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]
|
CTD |
PMID:15708576 |
|
NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
|
|
G
|
Egr1
|
early growth response 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of EGR1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843
|
|
G
|
Eif1
|
eukaryotic translation initiation factor 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EIF1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr10:85,747,064...85,749,447
Ensembl chr 5:25,895,968...25,896,654 Ensembl chr10:25,895,968...25,896,654
|
|
G
|
Eif3e
|
eukaryotic translation initiation factor 3 subunit E
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of EIF3E mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 7:76,224,567...76,257,346
Ensembl chr 7:76,224,568...76,257,785
|
|
G
|
Eif5
|
eukaryotic translation initiation factor 5
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of EIF5 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 6:136,410,333...136,418,827
Ensembl chr 6:136,407,440...136,418,821
|
|
G
|
Eif5a
|
eukaryotic translation initiation factor 5A
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of EIF5A mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr10:55,138,821...55,143,272
Ensembl chr10:55,138,823...55,143,330
|
|
G
|
Elk3
|
ETS transcription factor ELK3
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of ELK3 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 7:29,655,676...29,718,163
Ensembl chr 7:29,655,693...29,691,661
|
|
G
|
Emp1
|
epithelial membrane protein 1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of EMP1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 4:169,931,537...169,964,366
Ensembl chr 4:169,931,440...169,964,365
|
|
G
|
Enpp2
|
ectonucleotide pyrophosphatase/phosphodiesterase 2
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of ENPP2 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 7:88,092,140...88,214,758
Ensembl chr 7:88,092,140...88,214,957
|
|
G
|
Epcam
|
epithelial cell adhesion molecule
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of EPCAM mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 6:12,633,715...12,649,678
Ensembl chr 6:12,631,611...12,649,702
|
|
G
|
Epha1
|
Eph receptor A1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of EPHA1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 4:72,213,022...72,227,543
Ensembl chr 4:72,213,037...72,227,474
|
|
G
|
Ephb3
|
Eph receptor B3
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of EPHB3 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr11:93,345,098...93,363,775
Ensembl chr11:93,345,098...93,363,775
|
|
G
|
Eps8
|
EGFR pathway substrate 8, signaling adaptor
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of EPS8 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 4:172,119,497...172,291,670
Ensembl chr 4:172,119,497...172,218,160
|
|
G
|
Erbb2
|
erb-b2 receptor tyrosine kinase 2
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of ERBB2 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481
|
|
G
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Erbb4
|
erb-b2 receptor tyrosine kinase 4
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of ERBB4 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 9:76,973,386...78,045,633
Ensembl chr 9:76,973,227...78,045,772
|
|
G
|
Esr2
|
estrogen receptor 2
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of ESR2 mRNA; Methylnitronitrosoguanidine results in increased expression of ESR2 protein
|
CTD |
PMID:21628965 PMID:22330348 |
|
NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
|
|
G
|
Ets1
|
ETS proto-oncogene 1, transcription factor
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of ETS1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 8:39,303,936...39,426,022
Ensembl chr 8:39,303,925...39,426,021
|
|
G
|
Faslg
|
Fas ligand
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of FASLG protein
|
CTD |
PMID:24821435 |
|
NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503
|
|
G
|
Fasn
|
fatty acid synthase
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of FASN mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583
|
|
G
|
Fau
|
FAU ubiquitin like and ribosomal protein S30 fusion
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of FAU mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of FAU mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FAU mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 1:212,779,429...212,781,028
Ensembl chr 1:212,779,473...212,781,026 Ensembl chr 1:212,779,473...212,781,026
|
|
G
|
Fcer1a
|
Fc epsilon receptor Ia
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of FCER1A mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr13:88,218,427...88,224,723
Ensembl chr13:88,218,420...88,224,681
|
|
G
|
Fcgr2a
|
Fc gamma receptor 2A
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of FCGR3 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr13:85,813,516...85,830,269
Ensembl chr13:85,855,437...85,864,394 Ensembl chr13:85,855,437...85,864,394
|
|
G
|
Fcgrt
|
Fc gamma receptor and transporter
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of FCGRT mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 1:104,710,902...104,720,685
Ensembl chr 1:104,710,909...104,720,532
|
|
G
|
Fes
|
FES proto-oncogene, tyrosine kinase
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of FES mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 1:143,746,945...143,756,181
Ensembl chr 1:143,746,945...143,756,181
|
|
G
|
Fgf10
|
fibroblast growth factor 10
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of FGF10 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:52,533,939...52,610,980
|
|
G
|
Flt1
|
Fms related receptor tyrosine kinase 1
|
multiple interactions increases expression
|
EXP
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of FLT1 mRNA]
|
CTD |
PMID:20434464 |
|
NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750
|
|
G
|
Folr1
|
folate receptor alpha
|
increases methylation
|
ISO
|
Methylnitronitrosoguanidine results in increased methylation of FOLR1 promoter
|
CTD |
PMID:29644877 |
|
NCBI chr 1:165,631,462...165,650,430
Ensembl chr 1:165,631,462...165,642,669
|
|
G
|
Fosl1
|
FOS like 1, AP-1 transcription factor subunit
|
decreases expression multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of FOSL1 mRNA Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [FOSL1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [FOSL1 protein results in increased expression of RRM2 mRNA]
|
CTD |
PMID:12634122 PMID:26921499 |
|
NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:212,183,833...212,192,391
|
|
G
|
Fst
|
follistatin
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of FST mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 2:47,856,345...47,863,670
Ensembl chr 2:47,856,345...47,863,491
|
|
G
|
Fstl1
|
follistatin-like 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of FSTL1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of FSTL1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FSTL1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr11:76,400,870...76,454,053
Ensembl chr11:76,391,315...76,455,126
|
|
G
|
Fyn
|
FYN proto-oncogene, Src family tyrosine kinase
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of FYN mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr20:44,322,635...44,514,498
Ensembl chr20:44,322,361...44,515,479
|
|
G
|
Gadd45a
|
growth arrest and DNA-damage-inducible, alpha
|
decreases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in decreased expression of GADD45A mRNA Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of GADD45A mRNA]
|
CTD |
PMID:19851710 |
|
NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807
|
|
G
|
Gcgr
|
glucagon receptor
|
decreases expression
|
EXP
|
Methylnitronitrosoguanidine results in decreased expression of GCGR mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr10:106,306,803...106,314,970
Ensembl chr10:106,306,559...106,314,969
|
|
G
|
Gdf15
|
growth differentiation factor 15
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of GDF15 mRNA
|
CTD |
PMID:12634122 PMID:12773770 |
|
NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022
|
|
G
|
Gja1
|
gap junction protein, alpha 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of GJA1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of GJA1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GJA1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
|
|
G
|
Gjb2
|
gap junction protein, beta 2
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of GJB2 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr15:35,375,977...35,393,817
Ensembl chr15:35,375,692...35,393,877
|
|
G
|
Gli1
|
GLI family zinc finger 1
|
increases expression
|
EXP
|
MNNG increases expression of Gli1 mRNA in rat stomach
|
RGD |
PMID:30537251 |
RGD:150520178 |
NCBI chr 7:65,042,237...65,054,888
Ensembl chr 7:65,042,237...65,054,540
|
|
G
|
Gpc4
|
glypican 4
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of GPC4 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of GPC4 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GPC4 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr X:136,565,536...136,676,142
Ensembl chr X:136,565,591...136,676,057
|
|
G
|
Gss
|
glutathione synthetase
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of GSS mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 3:164,508,005...164,538,343
Ensembl chr 3:164,508,005...164,538,306
|
|
G
|
Gstm2
|
glutathione S-transferase mu 2
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of GSTM2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of GSTM2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GSTM2 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 2:198,312,179...198,316,962
|
|
G
|
Gsto1
|
glutathione S-transferase omega 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of GSTO1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of GSTO1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTO1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 1:256,662,377...256,672,515
Ensembl chr 1:256,662,531...256,676,167
|
|
G
|
Gstp1
|
glutathione S-transferase pi 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of GSTP1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of GSTP1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTP1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
|
|
G
|
Gtf2i
|
general transcription factor II I
|
multiple interactions
|
ISO
|
Methylnitronitrosoguanidine promotes the reaction [GTF2I protein binds to RRM2 promoter]
|
CTD |
PMID:26921499 |
|
NCBI chr12:28,037,344...28,112,677
Ensembl chr12:28,037,853...28,112,677
|
|
G
|
Gzmf
|
granzyme F
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of GZMG mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr15:33,975,543...33,997,505
Ensembl chr15:33,977,505...33,997,572
|
|
G
|
H2ax
|
H2A.X variant histone
|
increases expression multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form [[Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein] which results in increased expression of RRM2 mRNA] inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]; E2F3 protein inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]; RRM2 protein inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]
|
CTD |
PMID:26921499 PMID:27233451 PMID:38563870 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
|
|
G
|
H4c14
|
H4 clustered histone 14
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of H4C2 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 2:183,831,601...183,831,996
Ensembl chr 4:171,403,627...171,403,938 Ensembl chr17:171,403,627...171,403,938 Ensembl chr17:171,403,627...171,403,938 Ensembl chr17:171,403,627...171,403,938
|
|
G
|
Hba-a2
|
hemoglobin alpha, adult chain 2
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of HBA1 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr10:15,828,291...15,829,138
Ensembl chr10:15,828,377...15,829,141
|
|
G
|
Hes1
|
hes family bHLH transcription factor 1
|
increases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of HES1 protein weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of HES1 protein]
|
CTD |
PMID:36403744 |
|
NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061
|
|
G
|
Hes6
|
hes family bHLH transcription factor 6
|
multiple interactions increases expression
|
EXP
|
weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of HES6 protein]
|
CTD |
PMID:36403744 |
|
NCBI chr 9:99,449,375...99,451,343
Ensembl chr 9:99,449,371...99,451,096
|
|
G
|
Hif1a
|
hypoxia inducible factor 1 subunit alpha
|
increases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of HIF1A mRNA; Methylnitronitrosoguanidine results in increased expression of HIF1A protein corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of HIF1A mRNA]; weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of HIF1A protein]
|
CTD |
PMID:35103375 PMID:36403744 |
|
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
|
|
G
|
Hmgb1
|
high mobility group box 1
|
increases expression multiple interactions
|
ISO EXP
|
Methylnitronitrosoguanidine results in increased expression of HMGB1 mRNA corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of HMGB1 mRNA]
|
CTD |
PMID:12634122 PMID:35103375 |
|
NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327 Ensembl chr12:39,039,050...39,041,327
|
|
G
|
Hmgb2
|
high mobility group box 2
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of HMGB2 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr16:37,721,374...37,723,950
Ensembl chr16:37,721,379...37,723,860
|
|
G
|
Hpgd
|
15-hydroxyprostaglandin dehydrogenase
|
decreases expression
|
EXP
|
Methylnitronitrosoguanidine results in decreased expression of HPGD mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr16:38,996,876...39,034,831
Ensembl chr16:38,996,876...39,034,831
|
|
G
|
Hprt1
|
hypoxanthine phosphoribosyltransferase 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of HPRT1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of HPRT1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HPRT1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr X:137,655,744...137,687,718
Ensembl chr X:137,655,680...137,687,712
|
|
G
|
Hras
|
HRas proto-oncogene, GTPase
|
multiple interactions
|
ISO
|
Methylnitronitrosoguanidine inhibits the reaction [EGF protein results in increased activity of HRAS protein]
|
CTD |
PMID:15708576 |
|
NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590
|
|
G
|
Hsp90aa1
|
heat shock protein 90 alpha family class A member 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of HSP90AA1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499
|
|
G
|
Hsp90ab1
|
heat shock protein 90 alpha family class B member 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of HSP90AB1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926
|
|
G
|
Hsp90b1
|
heat shock protein 90 beta family member 1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of HSP90B1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:22,997,962...23,012,293
|
|
G
|
Hspa1a
|
heat shock protein family A (Hsp70) member 1A
|
decreases expression
|
EXP
|
Methylnitronitrosoguanidine results in decreased expression of HSPA1A mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979
|
|
G
|
Hspd1
|
heat shock protein family D (Hsp60) member 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of HSPD1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037
|
|
G
|
Icam1
|
intercellular adhesion molecule 1
|
decreases response to substance increases expression multiple interactions
|
ISO
|
ICAM1 protein results in decreased susceptibility to Methylnitronitrosoguanidine Methylnitronitrosoguanidine results in increased expression of ICAM1 mRNA; Methylnitronitrosoguanidine results in increased expression of ICAM1 protein prolinedithiocarbamate inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of ICAM1 protein]
|
CTD |
PMID:22001597 |
|
NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
|
|
G
|
Id1
|
inhibitor of DNA binding 1
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of ID1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:161,671,538...161,672,685
|
|
G
|
Ier3
|
immediate early response 3
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of IER3 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of IER3 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IER3 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377
|
|
G
|
Ifitm1
|
interferon induced transmembrane protein 1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of IFITM1 mRNA
|
CTD |
PMID:12634122 PMID:12773770 |
|
NCBI chr 1:205,496,757...205,498,796
Ensembl chr 1:205,496,807...205,498,776
|
|
G
|
Ifrd1
|
interferon-related developmental regulator 1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of IFRD1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 6:62,996,560...63,044,996
Ensembl chr 6:62,996,562...63,016,131
|
|
G
|
Igkc
|
immunoglobulin kappa constant
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of IGKC mRNA
|
CTD |
PMID:15120970 |
|
|
|
G
|
Igsf6
|
immunoglobulin superfamily, member 6
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of IGSF6 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 1:185,041,462...185,051,956
Ensembl chr 1:185,041,462...185,052,245
|
|
G
|
Ikbkb
|
inhibitor of nuclear factor kappa B kinase subunit beta
|
multiple interactions increases expression
|
EXP
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of IKBKB protein]
|
CTD |
PMID:19851710 |
|
NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911
|
|
G
|
Il1b
|
interleukin 1 beta
|
increases secretion multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in increased secretion of IL1B protein KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased secretion of IL1B protein]
|
CTD |
PMID:38184286 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
|
|
G
|
Il6
|
interleukin 6
|
multiple interactions increases secretion increases expression
|
ISO EXP
|
weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased secretion of IL6 protein] Methylnitronitrosoguanidine results in increased expression of IL6 protein weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of IL6 protein] KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased secretion of IL6 protein]
|
CTD |
PMID:36403744 PMID:38184286 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
|
|
G
|
Irak1
|
interleukin-1 receptor-associated kinase 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of IRAK1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of IRAK1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IRAK1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr X:156,919,927...156,929,825
Ensembl chr X:156,920,081...156,929,825
|
|
G
|
Itgb4
|
integrin subunit beta 4
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of ITGB4 mRNA
|
CTD |
PMID:12634122 PMID:12773770 |
|
NCBI chr10:101,705,592...101,741,933
Ensembl chr10:101,705,587...101,741,932
|
|
G
|
Jmjd6
|
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of JMJD6 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr10:102,539,935...102,545,986
Ensembl chr10:102,539,894...102,545,986
|
|
G
|
Jpt1
|
Jupiter microtubule associated homolog 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of JPT1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr10:101,243,428...101,261,464
Ensembl chr10:101,243,424...101,261,469
|
|
G
|
Junb
|
JunB proto-oncogene, AP-1 transcription factor subunit
|
multiple interactions
|
ISO
|
Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which results in increased expression of RRM2 mRNA]
|
CTD |
PMID:26921499 |
|
NCBI chr19:40,081,126...40,082,910
Ensembl chr19:40,073,541...40,085,218
|
|
G
|
Kctd12
|
potassium channel tetramerization domain containing 12
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of KCTD12 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr15:86,214,786...86,220,725
Ensembl chr15:86,214,840...86,224,539
|
|
G
|
Kdm8
|
lysine demethylase 8
|
multiple interactions
|
ISO
|
Methylnitronitrosoguanidine inhibits the reaction [TP53 protein binds to KDM8 protein]
|
CTD |
PMID:26025680 |
|
NCBI chr 1:189,444,527...189,459,507
Ensembl chr 1:189,444,555...189,459,491
|
|
G
|
Kit
|
KIT proto-oncogene receptor tyrosine kinase
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of KIT mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,903,033...32,978,812
|
|
G
|
Kitlg
|
KIT ligand
|
decreases expression
|
EXP
|
Methylnitronitrosoguanidine results in decreased expression of KITLG mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:36,782,638...36,863,793
|
|
G
|
Klf10
|
KLF transcription factor 10
|
decreases expression
|
EXP
|
Methylnitronitrosoguanidine results in decreased expression of KLF10 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 7:71,352,612...71,358,680
Ensembl chr 7:71,350,573...71,358,948
|
|
G
|
Klf7
|
KLF transcription factor 7
|
multiple interactions increases expression
|
ISO
|
KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 mRNA]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 protein]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CDH2 mRNA]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CDH2 protein]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKB1 protein]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RELA protein]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of SNAI1 protein]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TWIST1 protein]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of VIM mRNA]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of VIM protein]]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of KLF7 mRNA]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of KLF7 protein] KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 mRNA]; KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of CDH2 mRNA]; KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of NFKB1 protein]; KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of SNAI1 protein]; KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of TWIST1 protein]; KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of VIM mRNA]; KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased phosphorylation of RELA protein]; KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased secretion of IL1B protein]; KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased secretion of IL6 protein] Methylnitronitrosoguanidine results in increased expression of KLF7 mRNA; Methylnitronitrosoguanidine results in increased expression of KLF7 protein
|
CTD |
PMID:38184286 |
|
NCBI chr 9:72,927,485...73,020,167
Ensembl chr 9:72,933,136...73,020,056
|
|
G
|
Kras
|
KRAS proto-oncogene, GTPase
|
multiple interactions increases expression
|
EXP
|
geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of KRAS mRNA]
|
CTD |
PMID:28428697 |
|
NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320
|
|
G
|
Krt17
|
keratin 17
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of KRT17 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr10:85,679,068...85,683,792
Ensembl chr10:85,679,070...85,683,787
|
|
G
|
Ldha
|
lactate dehydrogenase A
|
multiple interactions increases expression
|
EXP
|
corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of LDHA mRNA]
|
CTD |
PMID:35103375 |
|
NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521
|
|
G
|
Lgals3
|
galectin 3
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LGALS3 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr15:23,099,795...23,111,731
Ensembl chr15:23,086,841...23,111,737
|
|
G
|
Lgals8
|
galectin 8
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of LGALS8 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr17:62,716,368...62,744,272
Ensembl chr17:62,719,828...62,744,482
|
|
G
|
Lig1
|
DNA ligase 1
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of LIG1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 1:83,243,043...83,281,707
Ensembl chr 1:83,219,545...83,281,708
|
|
G
|
Lipa
|
lipase A, lysosomal acid type
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of LIP1 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 1:241,437,524...241,470,936
Ensembl chr 1:241,437,524...241,470,740
|
|
G
|
Lox
|
lysyl oxidase
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of LOX mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of LOX mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of LOX mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810
|
|
G
|
Lpl
|
lipoprotein lipase
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of LPL mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of LPL mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of LPL mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107
|
|
G
|
Map2k1
|
mitogen activated protein kinase kinase 1
|
increases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of MAP2K1 mRNA geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of MAP2K1 mRNA]
|
CTD |
PMID:28428697 |
|
NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184
|
|
G
|
Map3k12
|
mitogen activated protein kinase kinase kinase 12
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of MAP3K12 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of MAP3K12 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MAP3K12 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 7:135,507,082...135,527,396
Ensembl chr 7:135,508,790...135,515,137
|
|
G
|
Mapk1
|
mitogen activated protein kinase 1
|
multiple interactions decreases phosphorylation
|
ISO
|
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased phosphorylation of MAPK1 protein]]
|
CTD |
PMID:17828454 |
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
|
|
G
|
Mapk14
|
mitogen activated protein kinase 14
|
increases phosphorylation
|
ISO
|
Methylnitronitrosoguanidine results in increased phosphorylation of MAPK14 protein
|
CTD |
PMID:22001597 |
|
NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294
|
|
G
|
Mapk3
|
mitogen activated protein kinase 3
|
multiple interactions decreases phosphorylation
|
ISO
|
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased phosphorylation of MAPK3 protein]]
|
CTD |
PMID:17828454 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
|
|
G
|
Mapk4
|
mitogen-activated protein kinase 4
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of MAPK4 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr18:69,788,058...69,937,524
Ensembl chr18:69,788,060...69,837,037
|
|
G
|
Mapk8
|
mitogen-activated protein kinase 8
|
increases phosphorylation
|
ISO
|
Methylnitronitrosoguanidine results in increased phosphorylation of MAPK8 protein
|
CTD |
PMID:22001597 |
|
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
|
|
G
|
Mapk9
|
mitogen-activated protein kinase 9
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of MAPK9 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228
|
|
G
|
Marcks
|
myristoylated alanine rich protein kinase C substrate
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of MARCKS mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of MARCKS mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MARCKS mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr20:42,240,185...42,245,882
Ensembl chr20:42,240,185...42,245,882
|
|
G
|
Max
|
MYC associated factor X
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of MAX mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 6:101,369,989...101,395,333
Ensembl chr 6:101,369,988...101,395,549
|
|
G
|
Mcam
|
melanoma cell adhesion molecule
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of MCAM mRNA
|
CTD |
PMID:12634122 PMID:12773770 |
|
NCBI chr 8:53,376,225...53,384,407
Ensembl chr 8:53,376,197...53,384,406
|
|
G
|
Mcm2
|
minichromosome maintenance complex component 2
|
decreases expression multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of MCM2 mRNA [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of MCM2 mRNA
|
CTD |
PMID:12634122 PMID:19840844 |
|
NCBI chr 4:122,903,679...122,918,205
Ensembl chr 4:122,903,682...122,918,094
|
|
G
|
Mcm4
|
minichromosome maintenance complex component 4
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of MCM4 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr11:98,762,599...98,776,300
Ensembl chr11:98,762,634...98,776,536
|
|
G
|
Mcm6
|
minichromosome maintenance complex component 6
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of MCM6 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr13:42,379,161...42,404,352
Ensembl chr13:42,379,162...42,465,467
|
|
G
|
Mcpt1
|
mast cell protease 1
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of MCPT1 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr15:33,841,606...33,844,174
Ensembl chr15:33,841,606...33,844,174
|
|
G
|
Mdm2
|
MDM2 proto-oncogene
|
increases expression multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of MDM2 mRNA Methylnitronitrosoguanidine results in increased expression of MDM2 protein Cadmium Chloride promotes the reaction [Methylnitronitrosoguanidine results in increased expression of MDM2 protein]
|
CTD |
PMID:12135628 PMID:12634122 |
|
NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791
|
|
G
|
Mecom
|
MDS1 and EVI1 complex locus
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of MECOM mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 2:114,837,815...115,393,052
Ensembl chr 2:114,837,840...115,393,038
|
|
G
|
Met
|
MET proto-oncogene, receptor tyrosine kinase
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of MET mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821
|
|
G
|
Mgmt
|
O-6-methylguanine-DNA methyltransferase
|
decreases response to substance
|
ISO
|
MGMT protein results in decreased susceptibility to Methylnitronitrosoguanidine
|
CTD |
PMID:1727384 PMID:15010311 PMID:16043385 |
|
NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482
|
|
G
|
Mgst2
|
microsomal glutathione S-transferase 2
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of MGST2 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 2:137,821,787...137,866,664
Ensembl chr 2:137,836,140...137,866,661
|
|
G
|
Mgst3
|
microsomal glutathione S-transferase 3
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of MGST3 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr13:82,059,480...82,080,418
Ensembl chr13:82,059,480...82,080,575
|
|
G
|
Mir21
|
microRNA 21
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of MIR21 mRNA
|
CTD |
PMID:24821435 |
|
NCBI chr10:71,902,600...71,902,691
|
|
G
|
Mki67
|
marker of proliferation Ki-67
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of MKI67 protein
|
CTD |
PMID:38563870 |
|
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
|
|
G
|
Mlh1
|
mutL homolog 1
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of MLH1 protein
|
CTD |
PMID:17671175 |
|
NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:120,065,900...120,112,011
|
|
G
|
Mmp2
|
matrix metallopeptidase 2
|
multiple interactions increases expression
|
EXP ISO
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of and results in increased activity of MMP2 protein]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of MMP2 mRNA]; Methylnitronitrosoguanidine results in increased expression of and results in increased activity of MMP2 protein [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of MMP2 mRNA
|
CTD |
PMID:19840844 PMID:20434464 |
|
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
|
|
G
|
Mmp9
|
matrix metallopeptidase 9
|
multiple interactions increases expression
|
EXP
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of and results in increased activity of MMP9 protein]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of MMP9 mRNA]; Methylnitronitrosoguanidine results in increased expression of and results in increased activity of MMP9 protein
|
CTD |
PMID:20434464 |
|
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
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|
G
|
Mpg
|
N-methylpurine-DNA glycosylase
|
increases response to substance
|
ISO
|
MPG protein results in increased susceptibility to Methylnitronitrosoguanidine
|
CTD |
PMID:15299078 |
|
NCBI chr10:15,900,697...15,906,981
Ensembl chr10:15,899,635...15,907,052
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G
|
Mpp1
|
MAGUK p55 scaffold protein 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of MPP1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of MPP1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MPP1 mRNA
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CTD |
PMID:19840844 |
|
|
|
G
|
Msh2
|
mutS homolog 2
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of MSH2 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503
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G
|
Mst1
|
macrophage stimulating 1
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of MST1 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 8:117,646,485...117,652,016
Ensembl chr 8:117,647,438...117,652,015
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|
G
|
Mt1a
|
metallothionein 1A
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of MT1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of MT1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MT1 mRNA
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CTD |
PMID:19840844 |
|
NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200 Ensembl chr X:79,695,809...79,696,200 Ensembl chr19:79,695,809...79,696,200
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|
G
|
Mthfr
|
methylenetetrahydrofolate reductase
|
increases methylation
|
ISO
|
Methylnitronitrosoguanidine results in increased methylation of MTHFR promoter
|
CTD |
PMID:29644877 |
|
NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:163,748,321...163,768,105
|
|
G
|
Mutyh
|
mutY DNA glycosylase
|
multiple interactions
|
ISO
|
MUTYH protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of PARP1 protein]
|
CTD |
PMID:26954031 |
|
NCBI chr 5:135,510,666...135,522,777
Ensembl chr 5:135,517,695...135,522,776
|
|
G
|
Mx2
|
MX dynamin like GTPase 2
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of MX2 mRNA
|
CTD |
PMID:12082013 |
|
NCBI chr11:50,375,101...50,399,373
Ensembl chr11:50,375,191...50,402,478
|
|
G
|
Mybl1
|
MYB proto-oncogene like 1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of MYBL1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 5:14,365,768...14,401,012
Ensembl chr 5:14,365,768...14,399,588
|
|
G
|
Myc
|
MYC proto-oncogene, bHLH transcription factor
|
increases expression multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of MYC protein Cadmium Chloride promotes the reaction [Methylnitronitrosoguanidine results in increased expression of MYC protein]
|
CTD |
PMID:12135628 |
|
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
|
|
G
|
Myl2
|
myosin light chain 2
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of MYL2 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr12:40,114,964...40,126,236
Ensembl chr12:40,114,958...40,129,149
|
|
G
|
Myl9
|
myosin light chain 9
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of MYL9 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 3:165,742,020...165,748,409
Ensembl chr 3:165,742,046...165,748,410
|
|
G
|
Mylk
|
myosin light chain kinase
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of MYLK mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr11:79,288,243...79,535,450
Ensembl chr11:79,288,243...79,535,659
|
|
G
|
Nbl1
|
NBL1, DAN family BMP antagonist
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of NBL1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 5:156,601,986...156,613,182
Ensembl chr 5:156,601,986...156,613,186
|
|
G
|
Nfkb1
|
nuclear factor kappa B subunit 1
|
multiple interactions increases expression
|
EXP ISO
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKB1 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKB1 protein] Methylnitronitrosoguanidine results in increased expression of NFKB1 mRNA; Methylnitronitrosoguanidine results in increased expression of NFKB1 protein KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKB1 protein]]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKB1 protein] KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of NFKB1 protein]
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CTD |
PMID:19851710 PMID:38184286 |
|
NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
|
|
G
|
Nfkbia
|
NFKB inhibitor alpha
|
multiple interactions decreases expression increases expression
|
EXP ISO
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of NFKBIA mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of NFKBIA protein]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKBIA protein modified form] Methylnitronitrosoguanidine results in decreased expression of NFKBIA mRNA; Methylnitronitrosoguanidine results in decreased expression of NFKBIA protein Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased degradation of NFKBIA protein
|
CTD |
PMID:19851710 PMID:22001597 |
|
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
|
|
G
|
Nfya
|
nuclear transcription factor Y subunit alpha
|
multiple interactions
|
ISO
|
Methylnitronitrosoguanidine promotes the reaction [NFYA protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYA protein results in increased expression of RRM2 mRNA]
|
CTD |
PMID:26921499 |
|
NCBI chr 9:20,085,067...20,111,521
Ensembl chr 9:20,085,073...20,111,504
|
|
G
|
Nfyb
|
nuclear transcription factor Y subunit beta
|
multiple interactions
|
ISO
|
Methylnitronitrosoguanidine promotes the reaction [NFYB protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYB protein results in increased expression of RRM2 mRNA]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein binds to RRM2 promoter]]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein results in increased expression of RRM2 mRNA]]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]
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CTD |
PMID:26921499 |
|
NCBI chr 7:22,852,543...22,868,116
Ensembl chr 7:22,852,546...22,882,294
|
|
G
|
Nfyc
|
nuclear transcription factor Y subunit gamma
|
multiple interactions
|
ISO
|
Methylnitronitrosoguanidine promotes the reaction [NFYC protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYC protein results in increased expression of RRM2 mRNA]
|
CTD |
PMID:26921499 |
|
NCBI chr 5:139,622,020...139,690,545
Ensembl chr 5:139,622,020...139,679,884
|
|
G
|
Nnmt
|
nicotinamide N-methyltransferase
|
increases activity
|
EXP
|
Methylnitronitrosoguanidine results in increased activity of NNMT protein
|
CTD |
PMID:6652621 |
|
NCBI chr 8:57,820,156...57,851,301
Ensembl chr 8:57,825,464...57,843,174
|
|
G
|
Nrp1
|
neuropilin 1
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of NRP1 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr19:73,256,557...73,411,705
Ensembl chr19:73,256,557...73,411,702
|
|
G
|
Odc1
|
ornithine decarboxylase 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of ODC1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146
|
|
G
|
Pa2g4
|
proliferation-associated 2G4
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of PA2G4 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 7:1,569,326...1,576,794
Ensembl chr 7:1,569,327...1,576,802
|
|
G
|
Parg
|
poly (ADP-ribose) glycohydrolase
|
multiple interactions affects response to substance
|
ISO
|
[Hydrolyzable Tannins results in decreased activity of PARG protein] which results in decreased susceptibility to Methylnitronitrosoguanidine; [nobotanin B results in decreased activity of PARG protein] which results in decreased susceptibility to Methylnitronitrosoguanidine; benzamide inhibits the reaction [PARG affects the susceptibility to Methylnitronitrosoguanidine]
|
CTD |
PMID:11593040 PMID:15591342 |
|
NCBI chr16:7,442,696...7,550,585
Ensembl chr16:7,442,726...7,550,584
|
|
G
|
Parp1
|
poly (ADP-ribose) polymerase 1
|
multiple interactions increases activity affects cleavage increases response to substance increases expression
|
ISO
|
[benzamide results in decreased activity of PARP1 protein] which results in decreased susceptibility to Methylnitronitrosoguanidine; [Methylnitronitrosoguanidine results in increased activity of PARP1 protein] which results in decreased abundance of NAD; benzamide inhibits the reaction [[Methylnitronitrosoguanidine results in increased activity of PARP1 protein] which results in decreased abundance of NAD]; Eugenol affects the reaction [Methylnitronitrosoguanidine affects the cleavage of PARP1 protein]; Hydrolyzable Tannins inhibits the reaction [[Methylnitronitrosoguanidine results in increased activity of PARP1 protein] which results in decreased abundance of NAD]; MUTYH protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of PARP1 protein] PARP1 protein results in increased susceptibility to Methylnitronitrosoguanidine
|
CTD |
PMID:11593040 PMID:20434464 PMID:22001597 PMID:26954031 |
|
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
|
|
G
|
Pcbp2
|
poly(rC) binding protein 2
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of PCBP2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of PCBP2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCBP2 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 7:135,483,702...135,508,254
Ensembl chr 7:135,483,856...135,509,412
|
|
G
|
Pcdh7
|
protocadherin 7
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of PCDH7 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr14:56,684,817...57,114,976
Ensembl chr14:56,687,725...57,112,665
|
|
G
|
Pcna
|
proliferating cell nuclear antigen
|
decreases expression multiple interactions increases expression
|
ISO EXP
|
Methylnitronitrosoguanidine results in decreased expression of PCNA mRNA Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA protein]; geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA protein] [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of PCNA mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of PCNA mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA mRNA; Cadmium Chloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of PCNA mRNA]; Cadmium Chloride promotes the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA protein] Methylnitronitrosoguanidine results in increased expression of PCNA mRNA; Methylnitronitrosoguanidine results in increased expression of PCNA protein
|
CTD |
PMID:11516527 PMID:12135628 PMID:12634122 PMID:19840844 PMID:19851710 PMID:22330348 PMID:28428697 More...
|
|
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
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G
|
Pdgfb
|
platelet derived growth factor subunit B
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of PDGFB mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:113,420,710...113,438,343
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|
G
|
Pdgfra
|
platelet derived growth factor receptor alpha
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of PDGFRA mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of PDGFRA mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PDGFRA mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,360,028...33,408,516
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|
G
|
Pdia3
|
protein disulfide isomerase family A, member 3
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of PDIA3 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of PDIA3 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PDIA3 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 3:128,841,781...128,865,733
Ensembl chr 3:128,841,917...128,867,327
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G
|
Pea15
|
proliferation and apoptosis adaptor protein 15
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of PEA15 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr13:87,190,189...87,199,811
Ensembl chr13:87,187,295...87,199,859
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G
|
Pgk1
|
phosphoglycerate kinase 1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of PGK1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr X:75,336,988...75,352,962
Ensembl chr X:75,336,687...75,352,959
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G
|
Pgr
|
progesterone receptor
|
decreases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in decreased expression of PGR protein geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of PGR protein]
|
CTD |
PMID:28428697 |
|
NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271
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|
G
|
Pik3cg
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
|
increases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of PIK3CG mRNA corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PIK3CG mRNA]
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CTD |
PMID:35103375 |
|
NCBI chr 6:54,494,247...54,529,563
Ensembl chr 6:54,478,603...54,529,509
|
|
G
|
Pik3r1
|
phosphoinositide-3-kinase regulatory subunit 1
|
increases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of PIK3R1 mRNA geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PIK3R1 mRNA]
|
CTD |
PMID:28428697 |
|
NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347
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|
G
|
Plxna3
|
plexin A3
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of PLXNA3 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr X:157,266,986...157,282,896
Ensembl chr X:157,267,107...157,282,891
|
|
G
|
Podxl
|
podocalyxin-like
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of PODXL mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of PODXL mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 4:61,102,434...61,149,131
Ensembl chr 4:61,102,419...61,149,789
|
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G
|
Postn
|
periostin
|
decreases expression
|
EXP
|
Methylnitronitrosoguanidine results in decreased expression of POSTN mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 2:140,677,774...140,709,304
Ensembl chr 2:140,677,754...140,709,300
|
|
G
|
Ppp2r2a
|
protein phosphatase 2, regulatory subunit B, alpha
|
decreases response to substance
|
ISO
|
PPP2R2A protein results in decreased susceptibility to Methylnitronitrosoguanidine
|
CTD |
PMID:25772433 |
|
NCBI chr15:45,380,142...45,439,428
Ensembl chr15:45,379,683...45,439,405
|
|
G
|
Ppp2r5c
|
protein phosphatase 2, regulatory subunit B', gamma
|
increases response to substance
|
ISO
|
PPP2R5C protein results in increased susceptibility to Methylnitronitrosoguanidine
|
CTD |
PMID:25772433 |
|
NCBI chr 6:135,282,947...135,419,591
Ensembl chr 6:135,324,067...135,419,597
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|
G
|
Ppp2r5e
|
protein phosphatase 2 regulatory subunit B', epsilon
|
decreases response to substance
|
ISO
|
PPP2R5E protein results in decreased susceptibility to Methylnitronitrosoguanidine
|
CTD |
PMID:25772433 |
|
NCBI chr 6:99,904,569...100,053,672
Ensembl chr 6:99,904,569...100,053,573
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|
G
|
Prkd1
|
protein kinase D1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of PRKD1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 6:73,460,640...73,774,433
Ensembl chr 6:73,460,640...73,836,509
|
|
G
|
Pten
|
phosphatase and tensin homolog
|
decreases response to substance decreases expression multiple interactions
|
ISO EXP
|
PTEN protein results in decreased susceptibility to Methylnitronitrosoguanidine Methylnitronitrosoguanidine results in decreased expression of PTEN protein geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of PTEN protein]
|
CTD |
PMID:20530668 PMID:28428697 |
|
NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330
|
|
G
|
Ptn
|
pleiotrophin
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of PTN mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of PTN mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PTN mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 4:66,260,764...66,342,614
Ensembl chr 4:66,260,764...66,342,482
|
|
G
|
Ptp4a1
|
protein tyrosine phosphatase 4A1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of PTP4A1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 9:40,710,250...40,718,176
Ensembl chr 9:40,710,250...40,718,176
|
|
G
|
Ptpra
|
protein tyrosine phosphatase, receptor type, A
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of PTPRA mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 3:138,103,261...138,212,835
Ensembl chr 3:138,098,110...138,213,126
|
|
G
|
Ptprg
|
protein tyrosine phosphatase, receptor type, G
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of PTPRG mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr15:15,298,669...15,982,581
Ensembl chr15:15,302,133...15,982,668
|
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G
|
Ptprs
|
protein tyrosine phosphatase, receptor type, S
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of PTPRS mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 9:1,332,558...1,394,161
Ensembl chr 9:1,332,559...1,394,093
|
|
G
|
Pttg1
|
PTTG1 regulator of sister chromatid separation, securin
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of PTTG1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of PTTG1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTTG1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr10:28,394,940...28,406,410
Ensembl chr10:28,394,814...28,406,309
|
|
G
|
Pura
|
purine rich element binding protein A
|
multiple interactions
|
ISO
|
Methylnitronitrosoguanidine promotes the reaction [PURA protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [PURA protein results in increased expression of RRM2 mRNA]
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CTD |
PMID:26921499 |
|
NCBI chr18:28,159,103...28,179,539
Ensembl chr18:28,125,126...28,211,111
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G
|
Racgap1
|
Rac GTPase-activating protein 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of RACGAP1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 7:132,629,789...132,659,738
Ensembl chr 7:132,620,595...132,659,738
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|
G
|
Rad21
|
RAD21 cohesin complex component
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of RAD21 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 7:85,177,715...85,204,657
Ensembl chr 7:85,177,716...85,204,657
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|
G
|
Rad23a
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RAD23 homolog A, nucleotide excision repair protein
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of RAD23A mRNA
|
CTD |
PMID:12634122 PMID:12773770 |
|
NCBI chr19:40,219,235...40,225,543
Ensembl chr19:40,219,636...40,225,543
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|
G
|
Rbbp5
|
RB binding protein 5, histone lysine methyltransferase complex subunit
|
increases expression
|
ISO
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Methylnitronitrosoguanidine results in increased expression of RBBP5 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr13:46,464,389...46,494,244
Ensembl chr13:46,464,389...46,491,238
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|
G
|
Rbm6
|
RNA binding motif protein 6
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of RBM6 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 8:117,327,607...117,431,397
Ensembl chr 8:117,331,325...117,431,397
|
|
G
|
Reck
|
reversion-inducing-cysteine-rich protein with kazal motifs
|
multiple interactions decreases expression
|
EXP
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of RECK mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of RECK protein] Methylnitronitrosoguanidine results in decreased expression of RECK mRNA; Methylnitronitrosoguanidine results in decreased expression of RECK protein
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CTD |
PMID:20434464 |
|
NCBI chr 5:62,898,717...62,965,274
Ensembl chr 5:62,898,668...62,965,270
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|
G
|
Rela
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RELA proto-oncogene, NF-kB subunit
|
multiple interactions increases expression increases phosphorylation
|
EXP ISO
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RELA mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RELA protein] Methylnitronitrosoguanidine results in increased expression of RELA mRNA; Methylnitronitrosoguanidine results in increased expression of RELA protein KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased phosphorylation of RELA protein] KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RELA protein]]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RELA protein]
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CTD |
PMID:19851710 PMID:38184286 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
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|
G
|
Reln
|
reelin
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increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of RELN mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 4:13,628,440...14,055,201
Ensembl chr 4:13,628,399...14,055,162
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|
G
|
Rgs18
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regulator of G-protein signaling 18
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of RGS18 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr13:59,043,431...59,066,342
Ensembl chr13:59,043,431...59,066,342
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|
G
|
Ros1
|
ROS proto-oncogene 1 , receptor tyrosine kinase
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of ROS1 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr20:31,975,328...32,126,675
Ensembl chr20:31,975,329...32,126,547
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|
G
|
Rpl7
|
ribosomal protein L7
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of RPL7 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of RPL7 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPL7 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 5:8,000,446...8,003,454
Ensembl chr 5:7,850,630...8,003,451
|
|
G
|
Rps11
|
ribosomal protein S11
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPS11 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 1:104,742,153...104,744,261
Ensembl chr 1:104,742,155...104,744,337
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|
G
|
Rps20
|
ribosomal protein S20
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of RPS20 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of RPS20 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPS20 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 5:21,616,687...21,618,068
Ensembl chr 3:42,839,965...43,095,621 Ensembl chr 9:42,839,965...43,095,621 Ensembl chr 5:42,839,965...43,095,621
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|
G
|
Rpsa
|
ribosomal protein SA
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of RPSA mRNA
|
CTD |
PMID:12773770 |
|
NCBI chr 8:128,728,761...128,732,736
Ensembl chr 8:128,728,862...128,732,737
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|
G
|
Rrm2
|
ribonucleotide reductase regulatory subunit M2
|
increases expression multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA [[Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein] which results in increased expression of RRM2 mRNA] inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]; [Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein] which results in increased expression of RRM2 mRNA; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; CHIR-124 inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [DP1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [DP1 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [E2F1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [E2F1 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [E2F3 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [E2F3 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [FOSL1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [FOSL1 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [GTF2I protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [IFI16 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [IFI16 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [NFYA protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYA protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [NFYB protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYB protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [NFYC protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYC protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [PURA protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [PURA protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [RUVBL1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [RUVBL1 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [YY1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [YY1 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine results in increased expression of and affects the localization of RRM2 protein; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein binds to RRM2 promoter]]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein results in increased expression of RRM2 mRNA]]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; RRM2 protein inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]
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CTD |
PMID:26921499 |
|
NCBI chr 6:47,044,755...47,075,370
Ensembl chr 6:47,067,690...47,075,370
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|
G
|
Rrm2b
|
ribonucleotide reductase regulatory TP53 inducible subunit M2B
|
increases expression affects expression multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of RRM2B mRNA Methylnitronitrosoguanidine affects the expression of RRM2B mRNA ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein]; CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein]; E2F1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B mRNA]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B mRNA]; Methylnitronitrosoguanidine results in increased expression of and affects the localization of RRM2B protein; TP53 protein mutant form inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein]
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CTD |
PMID:21704725 PMID:26921499 |
|
NCBI chr 7:70,962,008...70,993,726
Ensembl chr 7:70,965,590...70,993,670
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|
G
|
RT1-Db1
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RT1 class II, locus Db1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of HLA-DRB1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr20:4,550,594...4,560,182
Ensembl chr20:4,550,596...4,560,165
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|
G
|
Ruvbl1
|
RuvB-like AAA ATPase 1
|
multiple interactions
|
ISO
|
Methylnitronitrosoguanidine promotes the reaction [RUVBL1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [RUVBL1 protein results in increased expression of RRM2 mRNA]
|
CTD |
PMID:26921499 |
|
NCBI chr 4:122,489,754...122,524,666
Ensembl chr 4:122,489,680...122,524,665
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|
G
|
Sec61g
|
Sec61 translocon subunit gamma
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SEC61G mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr14:95,113,083...95,119,458
Ensembl chr 9:48,798,504...48,798,710 Ensembl chr14:48,798,504...48,798,710
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|
G
|
Selenop
|
selenoprotein P
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of SELENOP mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of SELENOP mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SELENOP mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 2:54,225,736...54,236,022
Ensembl chr 2:54,225,152...54,236,019
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|
G
|
Serpine1
|
serpin family E member 1
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of SERPINE1 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357
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|
G
|
Serping1
|
serpin family G member 1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of SERPING1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 3:90,249,410...90,259,299
Ensembl chr 3:90,249,423...90,258,717
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|
G
|
Slc16a3
|
solute carrier family 16 member 3
|
increases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of SLC16A3 mRNA corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of SLC16A3 mRNA]
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CTD |
PMID:35103375 |
|
NCBI chr10:106,712,328...106,756,168
Ensembl chr10:106,714,466...106,720,903
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|
G
|
Smad2
|
SMAD family member 2
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of SMAD2 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr18:72,124,792...72,193,345
Ensembl chr18:72,124,863...72,187,388
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|
G
|
Smo
|
smoothened, frizzled class receptor
|
increases expression
|
EXP
|
MNNG increases expression of Smo mRNA in rat stomach
|
RGD |
PMID:30537251 |
RGD:150520178 |
NCBI chr 4:59,311,084...59,341,280
Ensembl chr 4:59,311,041...59,341,281
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|
G
|
Snai1
|
snail family transcriptional repressor 1
|
increases expression multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of SNAI1 protein KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of SNAI1 protein] KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of SNAI1 protein]]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of SNAI1 protein]
|
CTD |
PMID:38184286 |
|
NCBI chr 3:176,667,476...176,671,965
|
|
G
|
Snora62
|
small nucleolar RNA, H/ACA box 62
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of SNORA62 mRNA
|
CTD |
PMID:12773770 |
|
NCBI chr 8:119,853,958...119,854,106
Ensembl chr 8:128,731,591...128,731,739
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G
|
Snrpn
|
small nuclear ribonucleoprotein polypeptide N
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of SNRPN mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 1:120,316,846...120,338,919
Ensembl chr 1:120,315,556...120,323,924
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|
G
|
Sparc
|
secreted protein acidic and cysteine rich
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of SPARC mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr10:40,017,065...40,038,816
Ensembl chr10:40,017,075...40,039,268
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|
G
|
Spink1
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serine peptidase inhibitor, Kazal type 1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of SPINK1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr18:36,121,626...36,133,596
Ensembl chr18:36,076,399...36,133,545
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|
G
|
Spint2
|
serine peptidase inhibitor, Kunitz type, 2
|
decreases expression increases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of SPINT2 mRNA Methylnitronitrosoguanidine results in increased expression of SPINT2 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 1:93,685,637...93,708,091
Ensembl chr 1:93,685,641...93,708,091
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|
G
|
Spp1
|
secreted phosphoprotein 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of SPP1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of SPP1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SPP1 mRNA
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CTD |
PMID:19840844 |
|
NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820
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G
|
Sqle
|
squalene epoxidase
|
increases expression multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of SQLE mRNA [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of SQLE mRNA
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CTD |
PMID:12634122 PMID:19840844 |
|
NCBI chr 7:92,758,175...92,773,049
Ensembl chr 7:92,757,409...92,773,050
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|
G
|
Srsf7
|
serine and arginine rich splicing factor 7
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of SRSF7 mRNA
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CTD |
PMID:12634122 |
|
NCBI chr 6:20,564,035...20,571,205
Ensembl chr 6:20,564,044...20,571,212
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G
|
Stk39
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serine threonine kinase 39
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of STK39 mRNA
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CTD |
PMID:12634122 |
|
NCBI chr 3:73,321,522...73,588,397
Ensembl chr 3:73,321,522...73,586,740
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G
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Sufu
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SUFU negative regulator of hedgehog signaling
|
decreases expression
|
EXP
|
MNNG decreases expression of Sufu mRNA in rat stomach
|
RGD |
PMID:30537251 |
RGD:150520178 |
NCBI chr 1:255,199,108...255,296,983
Ensembl chr 1:255,199,164...255,296,981
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|
G
|
Sumo2
|
small ubiquitin-like modifier 2
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of SUMO2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of SUMO2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SUMO2 mRNA
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CTD |
PMID:19840844 |
|
NCBI chr10:101,270,899...101,283,458
Ensembl chr10:101,270,900...101,283,938 Ensembl chr 5:101,270,900...101,283,938
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G
|
Syn1
|
synapsin I
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of SYN1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of SYN1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SYN1 mRNA
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CTD |
PMID:19840844 |
|
NCBI chr X:3,725,745...3,780,940
Ensembl chr X:3,725,714...3,780,938
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G
|
Tbrg4
|
transforming growth factor beta regulator 4
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of TBRG4 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr14:85,696,738...85,704,691
Ensembl chr14:85,695,893...85,704,659
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|
G
|
Tgfb1
|
transforming growth factor, beta 1
|
increases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of TGFB1 mRNA geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TGFB1 mRNA]
|
CTD |
PMID:28428697 |
|
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
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|
G
|
Thbs1
|
thrombospondin 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of THBS1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of THBS1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of THBS1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402
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G
|
Thbs2
|
thrombospondin 2
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of THBS2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of THBS2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of THBS2 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 1:64,343,523...64,372,918
Ensembl chr 1:64,343,523...64,372,918
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|
G
|
Tiam1
|
TIAM Rac1 associated GEF 1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of TIAM1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr11:42,517,527...42,866,280
Ensembl chr11:42,517,528...42,646,075
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G
|
Timp2
|
TIMP metallopeptidase inhibitor 2
|
decreases expression multiple interactions
|
EXP ISO
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Methylnitronitrosoguanidine results in decreased expression of TIMP2 mRNA; Methylnitronitrosoguanidine results in decreased expression of TIMP2 protein Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of TIMP2 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of TIMP2 protein] [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of TIMP2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of TIMP2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TIMP2 mRNA
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CTD |
PMID:19840844 PMID:20434464 |
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NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214
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G
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Tlr2
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toll-like receptor 2
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increases expression multiple interactions
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EXP
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Methylnitronitrosoguanidine results in increased expression of TLR2 protein weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TLR2 protein]
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CTD |
PMID:36403744 |
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NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194
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G
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Tlr4
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toll-like receptor 4
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increases expression
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EXP
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Methylnitronitrosoguanidine results in increased expression of TLR4 mRNA
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CTD |
PMID:15120970 |
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NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
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G
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Tmsb4x
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thymosin beta 4, X-linked
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multiple interactions
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ISO
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[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of TMSB4X mRNA
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CTD |
PMID:19840844 |
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NCBI chr X:30,761,611...30,763,612
Ensembl chr X:30,761,612...30,763,613
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G
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Tnc
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tenascin C
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increases expression
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ISO
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Methylnitronitrosoguanidine results in increased expression of TNC mRNA
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CTD |
PMID:12634122 |
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NCBI chr 5:82,391,340...82,476,197
Ensembl chr 5:82,391,340...82,476,131
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G
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Tnf
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tumor necrosis factor
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increases expression increases secretion multiple interactions
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EXP ISO
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Methylnitronitrosoguanidine results in increased expression of TNF protein Methylnitronitrosoguanidine results in increased secretion of TNF protein weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TNF protein] weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased secretion of TNF protein]
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CTD |
PMID:36403744 |
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NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
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G
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Tnfrsf25
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TNF receptor superfamily member 25
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increases expression
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ISO
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Methylnitronitrosoguanidine results in increased expression of TNFRSF25 mRNA
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CTD |
PMID:12634122 |
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NCBI chr 5:162,621,669...162,626,341
Ensembl chr 5:167,904,786...167,909,052
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G
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Top2a
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DNA topoisomerase II alpha
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multiple interactions
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ISO
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[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of TOP2A mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of TOP2A mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TOP2A mRNA
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CTD |
PMID:19840844 |
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NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366
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G
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Tp53
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tumor protein p53
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increases expression decreases response to substance increases response to substance increases acetylation multiple interactions decreases expression
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ISO EXP
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Methylnitronitrosoguanidine results in increased expression of TP53 mRNA; Methylnitronitrosoguanidine results in increased expression of TP53 protein TP53 protein mutant form results in decreased susceptibility to Methylnitronitrosoguanidine TP53 protein results in increased susceptibility to Methylnitronitrosoguanidine Methylnitronitrosoguanidine results in increased acetylation of TP53 protein Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of TP53 protein]; resveratrol inhibits the reaction [Methylnitronitrosoguanidine results in increased acetylation of TP53 protein] [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of TRP53 mRNA; Cadmium Chloride inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TRP53 protein] ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of TP53 protein]; CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of TP53 protein]; Methylnitronitrosoguanidine inhibits the reaction [TP53 protein binds to KDM8 protein]; TP53 protein mutant form inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein]
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CTD |
PMID:9667752 PMID:11516527 PMID:12135628 PMID:12634122 PMID:15589979 PMID:17147953 PMID:19851710 PMID:26025680 PMID:26921499 More...
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NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
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G
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Tram1
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translocation associated membrane protein 1
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increases expression
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ISO
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Methylnitronitrosoguanidine results in increased expression of TRAM1 mRNA
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CTD |
PMID:12634122 |
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NCBI chr 5:10,425,710...10,450,669
Ensembl chr 5:10,425,633...10,470,056
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G
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Tsc22d1
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TSC22 domain family, member 1
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decreases expression
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ISO
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Methylnitronitrosoguanidine results in decreased expression of TSC22D1 mRNA
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CTD |
PMID:12634122 |
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NCBI chr15:58,159,612...58,260,244
Ensembl chr15:58,159,952...58,183,322
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G
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Ttc3
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tetratricopeptide repeat domain 3
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multiple interactions
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ISO
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[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of TTC3 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of TTC3 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TTC3 mRNA
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CTD |
PMID:19840844 |
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NCBI chr11:47,158,766...47,258,612
Ensembl chr11:47,158,792...47,258,418
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G
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Twist1
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twist family bHLH transcription factor 1
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multiple interactions increases expression
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ISO
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KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TWIST1 protein]]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TWIST1 protein] KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of TWIST1 protein]
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CTD |
PMID:38184286 |
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NCBI chr 6:56,402,309...56,404,303
Ensembl chr 6:56,398,061...56,404,965
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G
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Txn1
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thioredoxin 1
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multiple interactions
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ISO
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[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of TXN1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of TXN1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TXN1 mRNA
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CTD |
PMID:19840844 |
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NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307
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G
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Ubc
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ubiquitin C
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multiple interactions
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ISO
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[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of UBC mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of UBC mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of UBC mRNA
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CTD |
PMID:19840844 |
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NCBI chr12:36,899,673...36,905,275
Ensembl chr12:36,900,127...36,905,275
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G
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Ubd
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ubiquitin D
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increases expression
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EXP
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Methylnitronitrosoguanidine results in increased expression of UBD mRNA
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CTD |
PMID:12082013 |
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NCBI chr20:1,390,734...1,392,685
Ensembl chr20:1,390,600...1,413,965
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G
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Uchl1
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ubiquitin C-terminal hydrolase L1
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increases expression
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ISO
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Methylnitronitrosoguanidine results in increased expression of UCHL1 mRNA
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CTD |
PMID:12634122 |
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NCBI chr14:41,838,859...41,849,743
Ensembl chr14:41,838,861...41,849,417
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G
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Ucp2
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uncoupling protein 2
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multiple interactions
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ISO
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[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of UCP2 mRNA
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CTD |
PMID:19840844 |
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NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:164,251,373...164,257,743
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G
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Vcam1
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vascular cell adhesion molecule 1
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increases expression multiple interactions
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EXP
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Methylnitronitrosoguanidine results in increased expression of VCAM1 protein weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of VCAM1 protein]
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CTD |
PMID:36403744 |
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NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801
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G
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Vim
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vimentin
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increases expression multiple interactions
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ISO
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Methylnitronitrosoguanidine results in increased expression of VIM mRNA; Methylnitronitrosoguanidine results in increased expression of VIM protein KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of VIM mRNA] KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of VIM mRNA]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of VIM protein]]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of VIM mRNA]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of VIM protein]
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CTD |
PMID:12634122 PMID:12773770 PMID:38184286 |
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NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746
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G
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Wars1
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tryptophanyl-tRNA synthetase 1
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decreases expression
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ISO
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Methylnitronitrosoguanidine results in decreased expression of WARS1 mRNA
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CTD |
PMID:12634122 |
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NCBI chr 6:133,540,463...133,571,645
Ensembl chr 6:133,539,744...133,571,645
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G
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Wnt2
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Wnt family member 2
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increases expression
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ISO
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Methylnitronitrosoguanidine results in increased expression of WNT2 mRNA
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CTD |
PMID:12634122 |
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NCBI chr 4:47,294,300...47,340,284
Ensembl chr 4:47,294,300...47,421,976
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G
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Yy1
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YY1 transcription factor
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multiple interactions
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ISO
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Methylnitronitrosoguanidine promotes the reaction [YY1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [YY1 protein results in increased expression of RRM2 mRNA]
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CTD |
PMID:26921499 |
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NCBI chr 6:133,471,615...133,500,875
Ensembl chr 6:133,471,562...133,497,257
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