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ONTOLOGY REPORT - ANNOTATIONS


Term:ATP synthase inhibitor
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Accession:CHEBI:20854 term browser browse the term
Definition:A mitochondrial respiratory-chain inhibitor that interferes with the action of ATP synthase.


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1,3-dicyclohexylcarbodiimide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc39a10 solute carrier family 39 member 10 JBrowse link 9 59,947,562 60,070,549 RGD:6480464
G Slc39a14 solute carrier family 39 member 14 JBrowse link 15 51,982,872 52,029,841 RGD:6480464
carbonyl cyanide p-trifluoromethoxyphenylhydrazone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Aqp9 aquaporin 9 JBrowse link 8 77,559,621 77,599,781 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Ccnc cyclin C JBrowse link 5 35,865,598 35,883,732 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Ccng1 cyclin G1 JBrowse link 10 25,903,925 25,910,298 RGD:6480464
G Cdk4 cyclin-dependent kinase 4 JBrowse link 7 70,345,971 70,352,689 RGD:6480464
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:6480464
G Comt catechol-O-methyltransferase JBrowse link 11 86,715,981 86,735,630 RGD:6480464
G Coq10a coenzyme Q10A JBrowse link 7 2,780,930 2,788,189 RGD:6480464
G Coq2 coenzyme Q2, polyprenyltransferase JBrowse link 14 10,581,102 10,601,093 RGD:6480464
G Coq3 coenzyme Q3 methyltransferase JBrowse link 5 36,024,673 36,056,664 RGD:6480464
G Coq4 coenzyme Q4 JBrowse link 3 8,349,386 8,357,719 RGD:6480464
G Coq5 coenzyme Q5, methyltransferase JBrowse link 12 47,078,753 47,095,438 RGD:6480464
G Coq6 coenzyme Q6 monooxygenase JBrowse link 6 108,076,393 108,087,782 RGD:6480464
G Coq7 coenzyme Q7, hydroxylase JBrowse link 1 188,176,060 188,190,874 RGD:6480464
G Coq8a coenzyme Q8A JBrowse link 13 98,451,629 98,480,438 RGD:6480464
G Coq9 coenzyme Q9 JBrowse link 19 10,583,855 10,596,848 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Ddb1 damage-specific DNA binding protein 1 JBrowse link 1 226,657,561 226,683,356 RGD:6480464
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 JBrowse link 5 57,028,467 57,039,378 RGD:6480464
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:6480464
G Ephx2 epoxide hydrolase 2 JBrowse link 15 42,757,241 42,794,211 RGD:6480464
G Fmr1 FMRP translational regulator 1 JBrowse link X 154,684,924 154,722,369 RGD:6480464
G Gadd45a growth arrest and DNA-damage-inducible, alpha JBrowse link 4 97,782,512 97,784,814 RGD:6480464
G Gdf15 growth differentiation factor 15 JBrowse link 16 20,555,395 20,557,978 RGD:6480464
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:6480464
G Gstm3 glutathione S-transferase mu 3 JBrowse link 2 210,685,204 210,688,273 RGD:6480464
G Gstm5 glutathione S-transferase, mu 5 JBrowse link 2 210,685,338 210,688,133 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Hmox2 heme oxygenase 2 JBrowse link 10 10,990,034 11,035,493 RGD:6480464
G Hsf1 heat shock transcription factor 1 JBrowse link 7 117,538,523 117,565,478 RGD:6480464
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 JBrowse link 6 135,107,262 135,112,793 RGD:6480464
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:6480464
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:6480464
G Hspa1l heat shock protein family A (Hsp70) member 1 like JBrowse link 20 4,879,998 4,965,191 RGD:6480464
G Hspa2 heat shock protein family A (Hsp70) member 2 JBrowse link 6 99,433,575 99,436,288 RGD:6480464
G Hspa4 heat shock protein family A (Hsp70) member 4 JBrowse link 10 38,601,624 38,642,397 RGD:6480464
G Hspa8 heat shock protein family A (Hsp70) member 8 JBrowse link 8 44,989,401 44,993,261 RGD:6480464
G Hspe1 heat shock protein family E (Hsp10) member 1 JBrowse link 9 61,691,246 61,724,948 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:6480464
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:6480464
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:6480464
G Kcnj12 potassium inwardly-rectifying channel, subfamily J, member 12 JBrowse link 10 47,282,208 47,343,501 RGD:6480464
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 JBrowse link 7 120,717,378 120,744,602 RGD:6480464
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:6480464
G Mt1 metallothionein 1 JBrowse link 19 11,301,991 11,303,007 RGD:6480464
G Mt2A metallothionein 2A JBrowse link 19 11,307,966 11,308,740 RGD:6480464
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:6480464
G Nipa1 NIPA magnesium transporter 1 JBrowse link 1 114,385,484 114,422,741 RGD:6480464
G Pdss1 decaprenyl diphosphate synthase subunit 1 JBrowse link 17 90,033,432 90,072,506 RGD:6480464
G Pdss2 decaprenyl diphosphate synthase subunit 2 JBrowse link 20 47,966,513 48,192,747 RGD:6480464
G Pink1 PTEN induced kinase 1 JBrowse link 5 156,677,146 156,689,258 RGD:6480464
G Plcg1 phospholipase C, gamma 1 JBrowse link 3 156,727,642 156,758,307 RGD:6480464
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A JBrowse link 1 101,511,899 101,515,043 RGD:6480464
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 2 54,857,688 54,893,404 RGD:6480464
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Rad23a RAD23 homolog A, nucleotide excision repair protein JBrowse link 19 25,949,488 25,956,677 RGD:6480464
G Rpl13a ribosomal protein L13A JBrowse link 1 101,120,325 101,123,401 RGD:6480464
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:6480464
G Slc18a2 solute carrier family 18 member A2 JBrowse link 1 280,397,831 280,457,968 RGD:6480464
G Slc41a2 solute carrier family 41 member 2 JBrowse link 7 26,522,314 26,607,861 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:6480464
G Tardbp TAR DNA binding protein JBrowse link 5 165,432,089 165,442,232 RGD:6480464
G Xrcc5 X-ray repair cross complementing 5 JBrowse link 9 79,659,275 79,748,050 RGD:6480464
oligomycin A term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp6v1h ATPase H+ transporting V1 subunit H JBrowse link 5 14,262,352 14,367,898 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Ccna2 cyclin A2 JBrowse link 2 123,274,727 123,282,266 RGD:6480464
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Ccne1 cyclin E1 JBrowse link 1 94,485,830 94,495,112 RGD:6480464
G Cd14 CD14 molecule JBrowse link 18 29,560,341 29,562,290 RGD:6480464
G Fut4 fucosyltransferase 4 JBrowse link 8 13,258,768 13,262,729 RGD:6480464
G Lamp1 lysosomal-associated membrane protein 1 JBrowse link 16 81,689,576 81,714,341 RGD:6480464
G Pink1 PTEN induced kinase 1 JBrowse link 5 156,677,146 156,689,258 RGD:6480464
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:6480464
G Sqstm1 sequestosome 1 JBrowse link 10 35,704,728 35,716,316 RGD:6480464
G Tfeb transcription factor EB JBrowse link 9 15,208,141 15,264,101 RGD:6480464
oligomycin B term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19748
    role 19695
      biological role 19693
        inhibitor 18167
          enzyme inhibitor 18089
            EC 3.* (hydrolase) inhibitor 17570
              EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor 4928
                ATP synthase inhibitor 85
                  1,3-dicyclohexylcarbodiimide 2
                  bedaquiline 0
                  bedaquiline fumarate 0
                  carbonyl cyanide p-trifluoromethoxyphenylhydrazone 72
                  oligomycin + 14
                  oligomycin mixture 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19748
    role 19695
      biological role 19693
        inhibitor 18167
          enzyme inhibitor 18089
            pathway inhibitor 8698
              electron-transport chain inhibitor 4756
                respiratory-chain inhibitor 3636
                  mitochondrial respiratory-chain inhibitor 3634
                    ATP synthase inhibitor 85
                      1,3-dicyclohexylcarbodiimide 2
                      bedaquiline 0
                      bedaquiline fumarate 0
                      carbonyl cyanide p-trifluoromethoxyphenylhydrazone 72
                      oligomycin + 14
                      oligomycin mixture 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.