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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:6-oxocampestanol
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Accession:CHEBI:20747 term browser browse the term
Definition:A 6-oxo steroid that has formula C28H48O2.
Synonyms:exact_synonym: 6-oxo-5alpha-campestan-3beta-ol
 related_synonym: (24R)-3beta-hydroxy-5alpha-ergostan-6-one;   Formula=C28H48O2;   InChI=1S/C28H48O2/c1-17(2)18(3)7-8-19(4)22-9-10-23-21-16-26(30)25-15-20(29)11-13-28(25,6)24(21)12-14-27(22,23)5/h17-25,29H,7-16H2,1-6H3/t18-,19-,20+,21+,22-,23+,24+,25-,27-,28-/m1/s1;   InChIKey=NBJZGNFIZZWBOJ-JSHJXQBASA-N;   SMILES=[H][C@@]1(CC[C@@]2([H])[C@]3([H])CC(=O)[C@@]4([H])C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CC[C@@H](C)C(C)C
 xref: Beilstein:7415873;   KEGG:C15789;   KNApSAcK:C00007273;   LIPID_MAPS_instance:LMST01030133
 xref_mesh: MESH:C411123


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6-oxocampestanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 B cell leukemia/lymphoma 2 decreases expression ISO 6-oxocampestanol results in decreased expression of BCL2 protein CTD PMID:32001316 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Bcl2l1 BCL2-like 1 affects expression ISO 6-oxocampestanol affects the expression of BCL2L1 protein CTD PMID:32001316 NCBI chr 2:152,758,732...152,833,803
Ensembl chr 2:152,780,668...152,831,728
JBrowse link
G Bid BH3 interacting domain death agonist affects expression ISO 6-oxocampestanol affects the expression of BID protein CTD PMID:32001316 NCBI chr 6:120,893,119...120,917,062
Ensembl chr 6:120,891,930...120,916,853
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO 6-oxocampestanol results in decreased expression of CCNB1 protein CTD PMID:32001316 NCBI chr13:100,778,739...100,786,486
Ensembl chr13:100,778,650...100,786,570
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) increases expression ISO 6-oxocampestanol results in increased expression of CDKN1A protein CTD PMID:32001316 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727
JBrowse link
G Esr1 estrogen receptor 1 (alpha) increases expression ISO 6-oxocampestanol results in increased expression of ESR1 protein CTD PMID:32001316 NCBI chr10:4,611,989...5,005,633
Ensembl chr10:4,611,593...5,005,614
JBrowse link
G Esr2 estrogen receptor 2 (beta) affects localization ISO 6-oxocampestanol affects the localization of ESR2 protein CTD PMID:32001316 NCBI chr12:76,120,419...76,177,259
Ensembl chr12:76,120,419...76,177,259
JBrowse link
G Pgr progesterone receptor affects localization ISO 6-oxocampestanol affects the localization of PGR protein CTD PMID:32001316 NCBI chr 9:8,898,900...8,968,611
Ensembl chr 9:8,899,833...8,968,611
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO 6-oxocampestanol results in increased expression of and results in increased phosphorylation of RB1 protein CTD PMID:32001316 NCBI chr14:73,192,858...73,325,951
Ensembl chr14:73,183,673...73,325,822
JBrowse link
G Trp53 transformation related protein 53 increases expression ISO 6-oxocampestanol results in increased expression of TP53 protein CTD PMID:32001316 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21746
    chemical entity 21744
      group 21620
        inorganic group 20502
          oxo group 19903
            organic oxo compound 19903
              carbonyl compound 19903
                ketone 17718
                  oxo steroid 9841
                    6-oxo steroid 19
                      6-oxocampestanol 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 21746
    subatomic particle 21732
      composite particle 21732
        hadron 21732
          baryon 21732
            nucleon 21732
              atomic nucleus 21732
                atom 21732
                  main group element atom 21647
                    p-block element atom 21647
                      carbon group element atom 21454
                        carbon atom 21353
                          organic molecular entity 21353
                            organic molecule 21249
                              organic cyclic compound 20838
                                organic polycyclic compound 17280
                                  steroid 13234
                                    hydroxy steroid 12816
                                      3-hydroxy steroid 10504
                                        sterol 454
                                          3beta-sterol 448
                                            campestanol 10
                                              6-oxocampestanol 10
paths to the root