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Accession:CHEBI:204928 term browser browse the term
Definition:A cephalosporin compound having acetoxymethyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups.
Synonyms:exact_synonym: 3-(acetoxymethyl)-7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3,4-didehydrocepham-4-carboxylic acid
 related_synonym: (6R,7R)-3-(acetoxymethyl)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;   (6R,7R)-3-Acetoxymethyl-7-{2-(2-amino-thiazol-4-yl)-2-[(Z)-methoxyimino]-acetylamino}-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid;   (6R,7R,Z)-3-(acetoxymethyl)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid;   Cephotaxime;   Formula=C16H17N5O7S2;   InChI=1S/C16H17N5O7S2/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26)/b20-9-/t10-,14-/m1/s1;   InChIKey=GPRBEKHLDVQUJE-QSWIMTSFSA-N;   SMILES=[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\\c1csc(N)n1)C(O)=O;   cefotaxima;   cefotaximum
 alt_id: CHEBI:112504;   CHEBI:3497;   CHEBI:41475
 xref: Beilstein:1096643 "Beilstein";   CAS:63527-52-6 "ChemIDplus";   CAS:63527-52-6 "DrugBank";   CAS:63527-52-6 "KEGG COMPOUND";   CAS:63527-52-6 "KEGG DRUG";   DrugBank:DB00493;   Drug_Central:546 "DrugCentral";   KEGG:C06885;   KEGG:D07647
 xref_mesh: MESH:D002439
 xref: PDBeChem:CE3;   PMID:10866367 "ChEMBL";   PMID:11034276 "Europe PMC";   PMID:11061623 "Europe PMC";   PMID:11677129 "ChEMBL";   PMID:12833570 "Europe PMC";   PMID:1384868 "Europe PMC";   PMID:14512220 "Europe PMC";   PMID:1502708 "Europe PMC";   PMID:15164972 "Europe PMC";   PMID:15361989 "Europe PMC";   PMID:15969234 "Europe PMC";   PMID:1635063 "ChEMBL";   PMID:17006042 "Europe PMC";   PMID:17386217 "Europe PMC";   PMID:18611527 "Europe PMC";   PMID:19741292 "Europe PMC";   PMID:21425867 "Europe PMC";   PMID:24038683 "Europe PMC";   PMID:24211456 "Europe PMC";   PMID:29017833 "Europe PMC";   PMID:9131470 "Europe PMC";   Patent:DE2556736;   Patent:DE2702501;   Patent:US4098888;   Patent:US4152432;   Reaxys:1096643 "Reaxys";   Wikipedia:Cefotaxime
 cyclic_relationship: is_conjugate_acid_of CHEBI:53670

show annotations for term's descendants       view all columns           Sort by:
cefotaxime term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Pgd phosphogluconate dehydrogenase JBrowse link 5 165,966,128 165,982,327 RGD:6480464
G RT1-CE5 RT1 class I, locus CE5 JBrowse link 20 4,892,702 4,896,993 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      biological role 19596
        antimicrobial agent 17143
          antibacterial agent 12897
            antibacterial drug 3035
              cefotaxime 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic group 18331
                              organic divalent group 18321
                                organodiyl group 18321
                                  carbonyl group 18209
                                    carbonyl compound 18209
                                      carboxylic acid 17908
                                        carboacyl group 16930
                                          univalent carboacyl group 16930
                                            carbamoyl group 16610
                                              carboxamide 16610
                                                lactam 2919
                                                  beta-lactam 707
                                                    beta-lactam antibiotic 695
                                                      cephem 535
                                                        cephalosporin 534
                                                          cefotaxime 5
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.