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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4-chloroaniline
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Accession:CHEBI:20331 term browser browse the term
Definition:A chloroaniline in which the chloro atom is para to the aniline amino group.
Synonyms:related_synonym: 4-Amino-1-chlorobenzene;   4-Chloro-phenylamine;   4-Chlorobenzenamine;   Formula=C6H6ClN;   InChI=1S/C6H6ClN/c7-5-1-3-6(8)4-2-5/h1-4H,8H2;   InChIKey=QSNSCYSYFYORTR-UHFFFAOYSA-N;   SMILES=Nc1ccc(Cl)cc1;   p-Chloroaniline;   para-Chloroaniline
 alt_id: CHEBI:116809;   CHEBI:34397
 xref: Beilstein:471359;   CAS:106-47-8;   KEGG:C14450
 xref_mesh: MESH:C004658
 xref: PMID:10848923;   PMID:24038698;   Reaxys:471359;   UM-BBD_compID:c0766;   Wikipedia:4-Chloroaniline


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4-chloroaniline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mpo myeloperoxidase multiple interactions ISO [[MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of 4-chloroaniline] which results in increased expression of MPO protein modified form; [MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of 4-chloroaniline CTD PMID:20199096 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Nat1 N-acetyltransferase 1 increases acetylation ISO NAT1 protein results in increased acetylation of 4-chloroaniline CTD PMID:15627487 NCBI chr16:23,970,742...23,991,573
Ensembl chr16:23,970,743...23,991,573
JBrowse link
G Nat2 N-acetyltransferase 2 increases acetylation ISO NAT2 protein results in increased acetylation of 4-chloroaniline CTD PMID:15627487 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570
JBrowse link
G Tp53 tumor protein p53 affects expression ISO 4-chloroaniline affects the expression of TP53 mRNA CTD PMID:27825931 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    chemical entity 19785
      molecular entity 19782
        polyatomic entity 19695
          heteroatomic molecular entity 19620
            halide 17977
              organohalogen compound 17713
                organochlorine compound 17466
                  chlorobenzenes 12990
                    chloroaniline 221
                      4-chloroaniline 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    main group molecular entity 19670
                      s-block molecular entity 19428
                        hydrogen molecular entity 19418
                          hydrides 18685
                            inorganic hydride 17409
                              pnictogen hydride 17381
                                nitrogen hydride 17223
                                  azane 16940
                                    ammonia 16939
                                      organic amino compound 16938
                                        aromatic amine 13616
                                          anilines 12327
                                            substituted aniline 11823
                                              chloroaniline 221
                                                4-chloroaniline 4
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