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ONTOLOGY REPORT - ANNOTATIONS
Term:3-hydroxybutyric acid
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Accession:CHEBI:20067 term browser browse the term
Definition:A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
Synonyms:related_synonym: (1)-3-Hydroxybutyric acid;   3 HBA;   3-Hydroxybuttersaeure;   3-OH-butyric acid;   3-hydroxybutanoic acid;   BHBA;   DL-beta-Hydroxybutyric acid;   Formula=C4H8O3;   InChI=1S/C4H8O3/c1-3(5)2-4(6)7/h3,5H,2H2,1H3,(H,6,7);   InChIKey=WHBMMWSBFZVSSR-UHFFFAOYSA-N;   SMILES=CC(O)CC(O)=O;   beta-Hydroxybuttersaeure;   beta-hydroxy-n-butyric acid;   beta-hydroxybutanoic acid;   beta-hydroxybutyric acid
 xref: Beilstein:773861 "Beilstein";   CAS:300-85-6 "ChemIDplus";   HMDB:HMDB0000357;   LIPID_MAPS_instance:LMFA01050005 "LIPID MAPS"
 xref_mesh: MESH:D020155
 xref: PMID:10855969 "Europe PMC";   PMID:17190852 "Europe PMC";   PMID:17579249 "Europe PMC";   PMID:6061736 "Europe PMC";   Reaxys:773861 "Reaxys";   Wikipedia:3-hydroxybutyrate
 cyclic_relationship: is_conjugate_acid_of CHEBI:37054

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3-hydroxybutyric acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aqp9 aquaporin 9 JBrowse link 8 77,559,621 77,599,781 RGD:6480464
G Atg5 autophagy related 5 JBrowse link 20 49,301,783 49,393,147 RGD:6480464
G Becn1 beclin 1 JBrowse link 10 89,209,944 89,225,297 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Ercc6 ERCC excision repair 6, chromatin remodeling factor JBrowse link 16 8,734,028 8,804,610 RGD:6480464
G Hcar2 hydroxycarboxylic acid receptor 2 JBrowse link 12 38,160,464 38,161,546 RGD:6480464
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 JBrowse link 2 200,452,623 200,480,785 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:6480464
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:6480464
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Ucp2 uncoupling protein 2 JBrowse link 1 165,506,375 165,512,744 RGD:6480464
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        biochemical role 19179
          metabolite 19151
            prokaryotic metabolite 18231
              bacterial metabolite 18231
                Mycoplasma genitalium metabolite 6865
                  butyric acid 5281
                    3-hydroxybutyric acid 14
                      (R)-3-hydroxybutyric acid + 0
                      (R)-3-hydroxybutyrylcarnitine 0
                      (S)-3-hydroxybutyric acid + 0
                      3-hydroxybutanoyl-CoA + 0
                      curtisian C 0
                      curtisian D 0
                      ethyl 3-hydroxybutyrate + 0
                      fleephilone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic group 18407
                              organic divalent group 18397
                                organodiyl group 18397
                                  carbonyl group 18285
                                    carbonyl compound 18285
                                      carboxylic acid 17940
                                        monocarboxylic acid 17260
                                          fatty acid 15814
                                            short-chain fatty acid 15510
                                              fatty acid 4:0 7007
                                                butyric acid 5281
                                                  hydroxybutyric acid 17
                                                    3-hydroxybutyric acid 14
                                                      (R)-3-hydroxybutyric acid + 0
                                                      (R)-3-hydroxybutyrylcarnitine 0
                                                      (S)-3-hydroxybutyric acid + 0
                                                      3-hydroxybutanoyl-CoA + 0
                                                      curtisian C 0
                                                      curtisian D 0
                                                      ethyl 3-hydroxybutyrate + 0
                                                      fleephilone 0
paths to the root

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