ONTOLOGY REPORT - ANNOTATIONS
Term: 3-hydroxybutyric acid
Accession: CHEBI:20067
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Definition: A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
Synonyms: related_synonym: (1)-3-Hydroxybutyric acid; 3 HBA; 3-Hydroxybuttersaeure; 3-OH-butyric acid; 3-hydroxybutanoic acid; BHBA; DL-beta-Hydroxybutyric acid; Formula=C4H8O3; InChI=1S/C4H8O3/c1-3(5)2-4(6)7/h3,5H,2H2,1H3,(H,6,7); InChIKey=WHBMMWSBFZVSSR-UHFFFAOYSA-N; SMILES=CC(O)CC(O)=O; beta-Hydroxybuttersaeure; beta-hydroxy-n-butyric acid; beta-hydroxybutanoic acid; beta-hydroxybutyric acid
xref: Beilstein:773861 "Beilstein"; CAS:300-85-6 "ChemIDplus"; HMDB:HMDB0000357; LIPID_MAPS_instance:LMFA01050005 "LIPID MAPS"
xref_mesh: MESH:D020155
xref: PMID:10855969 "Europe PMC"; PMID:17190852 "Europe PMC"; PMID:17579249 "Europe PMC"; PMID:6061736 "Europe PMC"; Reaxys:773861 "Reaxys"; Wikipedia:3-hydroxybutyrate
cyclic_relationship: is_conjugate_acid_of CHEBI:37054
G
Aqp9
aquaporin 9
8
77,559,621
77,599,781
RGD:6480464
G
Atg5
autophagy related 5
20
49,301,783
49,393,147
RGD:6480464
G
Becn1
beclin 1
10
89,209,944
89,225,297
RGD:6480464
G
Casp3
caspase 3
16
48,845,011
48,863,249
RGD:6480464
G
Casp9
caspase 9
5
160,356,211
160,373,774
RGD:6480464
G
Ercc6
ERCC excision repair 6, chromatin remodeling factor
16
8,734,028
8,804,610
RGD:6480464
G
Hcar2
hydroxycarboxylic acid receptor 2
12
38,160,464
38,161,546
RGD:6480464
G
Hmgcs2
3-hydroxy-3-methylglutaryl-CoA synthase 2
2
200,452,623
200,480,785
RGD:6480464
G
Nfe2l2
nuclear factor, erythroid 2-like 2
3
62,497,568
62,525,146
RGD:6480464
G
Ppara
peroxisome proliferator activated receptor alpha
7
126,618,872
126,687,282
RGD:6480464
G
Sirt1
sirtuin 1
20
26,831,971
26,851,587
RGD:6480464
G
Snca
synuclein alpha
4
90,782,412
90,883,236
RGD:6480464
G
Tp53
tumor protein p53
10
56,186,299
56,198,449
RGD:6480464
G
Ucp2
uncoupling protein 2
1
165,506,375
165,512,744
RGD:6480464
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