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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:19363 term browser browse the term
Definition:A member of the class of 1,4-benzoquinones that is p-benzoquinone in which the hydrogens at positions 2 and 5 are replaced by aziridin-1-yl groups.
Synonyms:exact_synonym: 2,5-bis(aziridin-1-yl)cyclohexa-2,5-diene-1,4-dione
 related_synonym: 2,5,-bis(ethyleneimine)-1,4-benzoquinone;   2,5,-bisethylene-imine-1,4-benzoquinone;   2,5-Bisaethyleniminobenzochinon-1,4;   2,5-bis(1-aziridinyl)-2,5-cyclohexadiene-1,4-dione;   2,5-bis(1-aziridinyl)-p-benzoquinone;   2,5-bis(1-aziridynyl)benzoquinone;   2,5-bis(aziridino)-1,4-benzoquinone;   2,5-bis(aziridino)benzoquinone;   2,5-bis(ethyleneimino)-1,4-benzoquinone;   2,5-bis-ethyleniminobenzoquinone;   2,5-bisethyleneiminebenzoquinone;   2,5-di(ethyleneimino)-1,4-benzoquinone;   2,5-diaziridinyl-1,4-benzoquinone;   3,6-diaziridinyl-1,4-benzoquinone;   DZQ;   Formula=C10H10N2O2;   InChI=1S/C10H10N2O2/c13-9-6-8(12-3-4-12)10(14)5-7(9)11-1-2-11/h5-6H,1-4H2;   InChIKey=RCWJMKCTHJPXJV-UHFFFAOYSA-N;   SMILES=O=C1C=C(N2CC2)C(=O)C=C1N1CC1;   TW 13;   ethylenimine quinone
 xref: Beilstein:169182;   CAS:526-62-5
 xref_mesh: MESH:C009970
 xref: PMID:10373575;   PMID:10978162;   PMID:11211879;   PMID:13415397;   PMID:17094478;   PMID:1751490;   PMID:8137269;   PMID:8461296;   PMID:9690517;   Reaxys:169182

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2,5-bis(aziridin-1-yl)-1,4-benzoquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [ethylenimine quinone results in increased expression of CDKN1A mRNA]
ethylenimine quinone results in increased expression of CDKN1A mRNA; ethylenimine quinone results in increased expression of CDKN1A protein
CTD PMID:8943236 PMID:9343371 PMID:9586815 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
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  CHEBI ontology 19841
    role 19792
      biological role 19792
        aetiopathogenetic role 18974
          genotoxin 16996
            mutagen 16807
              2,5-bis(aziridin-1-yl)-1,4-benzoquinone 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19732
                    p-block element atom 19732
                      carbon group element atom 19636
                        carbon atom 19625
                          organic molecular entity 19625
                            organic group 18537
                              organic divalent group 18528
                                organodiyl group 18528
                                  carbonyl group 18436
                                    carbonyl compound 18436
                                      ketone 16189
                                        cyclic ketone 13901
                                          quinone 8346
                                            benzoquinones 719
                                              1,4-benzoquinones 715
                                                2,5-bis(aziridin-1-yl)-1,4-benzoquinone 1
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