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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Pendulone
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Accession:CHEBI:193416 term browser browse the term
Synonyms:exact_synonym: 5-(7-hydroxy-3,4-dihydro-2H-chromen-3-yl)-2,3-dimethoxycyclohexa-2,5-diene-1,4-dione
 related_synonym: Formula=C17H16O6;   InChI=1S/C17H16O6/c1-21-16-13(19)7-12(15(20)17(16)22-2)10-5-9-3-4-11(18)6-14(9)23-8-10/h3-4,6-7,10,18H,5,8H2,1-2H3;   InChIKey=SHZOHJDZQPQBSW-UHFFFAOYSA-N;   SMILES=O1CC(CC2=C1C=C(O)C=C2)C=3C(=O)C(OC)=C(OC)C(=O)C3
 xref: Chemspider:4478538;   LIPID_MAPS_instance:LMPK12080052
 xref_mesh: MESH:C569898


show annotations for term's descendants           Sort by:
Pendulone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 increases expression ISO pendulone results in increased expression of ATF4 protein CTD PMID:35288263 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atf6 activating transcription factor 6 increases cleavage ISO pendulone results in increased cleavage of ATF6 protein CTD PMID:35288263 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO pendulone results in increased expression of BAX protein CTD PMID:35288263 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO pendulone results in decreased expression of BCL2 protein CTD PMID:35288263 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO pendulone results in increased expression of BID protein alternative form CTD PMID:35288263 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Casp3 caspase 3 increases activity ISO pendulone results in increased activity of CASP3 protein CTD PMID:35288263 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 increases activity ISO pendulone results in increased activity of CASP8 protein CTD PMID:35288263 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases activity ISO pendulone results in increased activity of CASP9 protein CTD PMID:35288263 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO pendulone results in increased expression of DDIT3 protein CTD PMID:35288263 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases phosphorylation		 ISO Acetylcysteine inhibits the reaction [pendulone results in increased phosphorylation of EIF2AK3 protein] CTD PMID:35288263 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation ISO pendulone results in increased phosphorylation of EIF2S1 protein CTD PMID:35288263 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Fas Fas cell surface death receptor increases expression ISO pendulone results in increased expression of FAS protein CTD PMID:35288263 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage		 ISO 4-phenylbutyric acid inhibits the reaction [pendulone results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [pendulone results in increased cleavage of PARP1 protein] CTD PMID:35288263 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b multiple interactions
increases expression		 ISO Acetylcysteine inhibits the reaction [pendulone results in increased expression of TNFRSF10A protein] CTD PMID:35288263 NCBI chr15:44,839,818...44,867,582
Ensembl chr15:44,840,386...44,867,467 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    chemical entity 19816
      atom 19816
        nonmetal atom 19749
          oxygen atom 19524
            oxygen molecular entity 19524
              flavonoids 11380
                isoflavonoid 3794
                  Pendulone 14
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    p-block element atom 19761
                      carbon group element atom 19703
                        carbon atom 19698
                          organic molecular entity 19698
                            organic molecule 19656
                              organic cyclic compound 19461
                                organic heterocyclic compound 18817
                                  oxacycle 17770
                                    benzopyran 11699
                                      1-benzopyran 11461
                                        isoflavonoid 3794
                                          Pendulone 14
paths to the root