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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:2-amino-4-(3-nitrophenyl)-3-cyano-7-(dimethylamino)-4H-chromene
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Accession:CHEBI:192743 term browser browse the term
Definition:A member of the class of chromenes that is 4H-chromene substituted by amino, cyano, 3-nitrophenyl, and dimethylamino groups at positions 2, 3, 4 and 7, respectively. It exhibits anti-cancer activity.
Synonyms:exact_synonym: 2-amino-7-(dimethylamino)-4-(3-nitrophenyl)-4H-chromene-3-carbonitrile
 related_synonym: 2-amino-7-(dimethylamino)-4-(3-nitrophenyl)-4H-1-benzopyran-3-carbonitrile;   3-NC;   Formula=C18H16N4O3;   InChI=1S/C18H16N4O3/c1-21(2)12-6-7-14-16(9-12)25-18(20)15(10-19)17(14)11-4-3-5-13(8-11)22(23)24/h3-9,17H,20H2,1-2H3;   InChIKey=PNHBABGLCCOXEK-UHFFFAOYSA-N;   SMILES=CN(C)C1=CC=C2C(C3=CC(=CC=C3)[N+]([O-])=O)C(C#N)=C(N)OC2=C1
 xref: PMID:21565459;   PMID:23054714;   PMID:26074734


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2-amino-4-(3-nitrophenyl)-3-cyano-7-(dimethylamino)-4H-chromene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO 3-NC decreases expression of BIRC3 protein in colorectal carcinoma cells RGD PMID:21565459 RGD:155226872 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19900
    role 19875
      biological role 19873
        biochemical role 19567
          apoptosis inducer 13634
            2-amino-4-(3-nitrophenyl)-3-cyano-7-(dimethylamino)-4H-chromene 1
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Term Annotations click to browse term
  CHEBI ontology 19900
    subatomic particle 19898
      composite particle 19898
        hadron 19898
          baryon 19898
            nucleon 19898
              atomic nucleus 19898
                atom 19898
                  main group element atom 19845
                    p-block element atom 19845
                      carbon group element atom 19792
                        carbon atom 19787
                          organic molecular entity 19787
                            organic molecule 19744
                              organic cyclic compound 19549
                                organic heterocyclic compound 18888
                                  oxacycle 17807
                                    benzopyran 11743
                                      1-benzopyran 11507
                                        chromenes 4404
                                          aminochromene 1
                                            2-amino-4-(3-nitrophenyl)-3-cyano-7-(dimethylamino)-4H-chromene 1
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