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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:2-amino-4-(3-nitrophenyl)-3-cyano-7-(dimethylamino)-4H-chromene
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Accession:CHEBI:192743 term browser browse the term
Definition:A member of the class of chromenes that is 4H-chromene substituted by amino, cyano, 3-nitrophenyl, and dimethylamino groups at positions 2, 3, 4 and 7, respectively. It exhibits anti-cancer activity.
Synonyms:exact_synonym: 2-amino-7-(dimethylamino)-4-(3-nitrophenyl)-4H-chromene-3-carbonitrile
 related_synonym: 2-amino-7-(dimethylamino)-4-(3-nitrophenyl)-4H-1-benzopyran-3-carbonitrile;   3-NC;   Formula=C18H16N4O3;   InChI=1S/C18H16N4O3/c1-21(2)12-6-7-14-16(9-12)25-18(20)15(10-19)17(14)11-4-3-5-13(8-11)22(23)24/h3-9,17H,20H2,1-2H3;   InChIKey=PNHBABGLCCOXEK-UHFFFAOYSA-N;   SMILES=CN(C)C1=CC=C2C(C3=CC(=CC=C3)[N+]([O-])=O)C(C#N)=C(N)OC2=C1
 xref: PMID:21565459;   PMID:23054714;   PMID:26074734


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2-amino-4-(3-nitrophenyl)-3-cyano-7-(dimethylamino)-4H-chromene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO 3-NC decreases expression of BIRC3 protein in colorectal carcinoma cells RGD PMID:21565459 RGD:155226872 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19867
    role 19837
      biological role 19835
        biochemical role 19552
          apoptosis inducer 13664
            2-amino-4-(3-nitrophenyl)-3-cyano-7-(dimethylamino)-4H-chromene 1
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Term Annotations click to browse term
  CHEBI ontology 19867
    subatomic particle 19865
      composite particle 19865
        hadron 19865
          baryon 19865
            nucleon 19865
              atomic nucleus 19865
                atom 19865
                  main group element atom 19803
                    p-block element atom 19803
                      carbon group element atom 19744
                        carbon atom 19740
                          organic molecular entity 19740
                            organic molecule 19692
                              organic cyclic compound 19482
                                organic heterocyclic compound 18872
                                  oxacycle 17903
                                    benzopyran 11976
                                      1-benzopyran 11730
                                        chromenes 4436
                                          aminochromene 1
                                            2-amino-4-(3-nitrophenyl)-3-cyano-7-(dimethylamino)-4H-chromene 1
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