CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: bromoacetate
Accession: CHEBI:192408
browse the term
Synonyms: exact_synonym: 2-bromoacetate
related_synonym: Formula=C2H2BrO2; InChI=1S/C2H3BrO2/c3-1-2(4)5/h1H2,(H,4,5)/p-1; InChIKey=KDPAWGWELVVRCH-UHFFFAOYSA-M; SMILES=BrCC([O-])=O
xref: CAS:68-10-0; Chemspider:5991
xref_mesh: MESH:C016274
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Aifm1
apoptosis inducing factor, mitochondria associated 1
increases expression
ISO
bromoacetate results in increased expression of AIFM1 mRNA
CTD
PMID:19753638
NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
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Atm
ATM serine/threonine kinase
increases expression
ISO
bromoacetate results in increased expression of ATM mRNA
CTD
PMID:19753638
NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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Atp23
ATP23 metallopeptidase and ATP synthase assembly factor homolog
decreases expression
ISO
bromoacetate results in decreased expression of ATP23 mRNA
CTD
PMID:19753638
NCBI chr 7:62,714,752...62,729,893
Ensembl chr 7:62,714,785...62,729,862
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Brca1
BRCA1, DNA repair associated
decreases expression
ISO
bromoacetate results in decreased expression of BRCA1 mRNA
CTD
PMID:19753638
NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
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Btg2
BTG anti-proliferation factor 2
decreases expression
ISO
bromoacetate results in decreased expression of BTG2 mRNA
CTD
PMID:19753638
NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
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Casp8
caspase 8
decreases expression increases expression
ISO
bromoacetate results in decreased expression of CASP8 mRNA bromoacetate results in increased expression of CASP8 mRNA
CTD
PMID:19753638
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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Ccl21
C-C motif chemokine ligand 21
decreases expression
ISO
bromoacetate results in decreased expression of CCL21 mRNA
CTD
PMID:19753638
NCBI chr 5:56,980,557...56,981,661
Ensembl chr 5:56,980,558...56,981,686
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Cryab
crystallin, alpha B
increases expression
ISO
bromoacetate results in increased expression of CRYAB mRNA
CTD
PMID:19753638
NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
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Csf2
colony stimulating factor 2
increases expression
ISO
bromoacetate results in increased expression of CSF2 mRNA
CTD
PMID:19753638
NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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Ddit3
DNA-damage inducible transcript 3
increases expression
ISO
bromoacetate results in increased expression of DDIT3 mRNA
CTD
PMID:19753638
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Dmc1
DNA meiotic recombinase 1
decreases expression
ISO
bromoacetate results in decreased expression of DMC1 mRNA
CTD
PMID:19753638
NCBI chr 7:111,124,888...111,167,465
Ensembl chr 7:111,124,888...111,167,952
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Egr1
early growth response 1
increases expression decreases expression
ISO
bromoacetate results in increased expression of EGR1 mRNA bromoacetate results in decreased expression of EGR1 mRNA
CTD
PMID:19753638
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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Fmo1
flavin containing dimethylaniline monoxygenase 1
decreases expression
ISO
bromoacetate results in decreased expression of FMO1 mRNA
CTD
PMID:19753638
NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
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Gdf15
growth differentiation factor 15
increases expression
ISO
bromoacetate results in increased expression of GDF15 mRNA
CTD
PMID:19753638
NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
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Gsr
glutathione-disulfide reductase
increases expression
ISO
bromoacetate results in increased expression of GSR mRNA
CTD
PMID:19753638
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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Hmox1
heme oxygenase 1
decreases expression increases expression
ISO
bromoacetate results in decreased expression of HMOX1 mRNA bromoacetate results in increased expression of HMOX1 mRNA
CTD
PMID:19753638 PMID:31755747
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Hspa1l
heat shock protein family A (Hsp70) member 1 like
decreases expression
ISO
bromoacetate results in decreased expression of HSPA1L mRNA
CTD
PMID:19753638
NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
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Hspa5
heat shock protein family A (Hsp70) member 5
increases expression
ISO
bromoacetate results in increased expression of HSPA5 mRNA
CTD
PMID:19753638
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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Il1a
interleukin 1 alpha
decreases expression increases expression
ISO
bromoacetate results in decreased expression of IL1A mRNA bromoacetate results in increased expression of IL1A mRNA
CTD
PMID:19753638
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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Il1b
interleukin 1 beta
increases expression
ISO
bromoacetate results in increased expression of IL1B mRNA
CTD
PMID:19753638
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il6
interleukin 6
decreases expression
ISO
bromoacetate results in decreased expression of IL6 mRNA
CTD
PMID:19753638
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Ip6k3
inositol hexakisphosphate kinase 3
increases expression
ISO
bromoacetate results in increased expression of IP6K3 mRNA
CTD
PMID:19753638
NCBI chr20:5,223,863...5,245,443
Ensembl chr20:5,224,120...5,245,428
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Lig1
DNA ligase 1
decreases expression
ISO
bromoacetate results in decreased expression of LIG1 mRNA
CTD
PMID:19753638
NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413
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Lta
lymphotoxin alpha
decreases expression increases expression
ISO
bromoacetate results in decreased expression of LTA mRNA bromoacetate results in increased expression of LTA mRNA
CTD
PMID:19753638
NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859
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Map2k6
mitogen-activated protein kinase kinase 6
decreases expression
ISO
bromoacetate results in decreased expression of MAP2K6 mRNA
CTD
PMID:19753638
NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
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Mlh1
mutL homolog 1
increases expression
ISO
bromoacetate results in increased expression of MLH1 mRNA
CTD
PMID:19753638
NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
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Mpg
N-methylpurine-DNA glycosylase
increases expression
ISO
bromoacetate results in increased expression of MPG mRNA
CTD
PMID:19753638
NCBI chr10:15,396,246...15,402,528
Ensembl chr10:15,395,782...15,402,520
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Mre11
MRE11 homolog, double strand break repair nuclease
increases expression
ISO
bromoacetate results in increased expression of MRE11 mRNA
CTD
PMID:19753638
NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279
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Nfkbia
NFKB inhibitor alpha
increases expression
ISO
bromoacetate results in increased expression of NFKBIA mRNA
CTD
PMID:19753638
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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Nos2
nitric oxide synthase 2
decreases expression
ISO
bromoacetate results in decreased expression of NOS2 mRNA
CTD
PMID:19753638
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Pcbp4
poly(rC) binding protein 4
decreases expression
ISO
bromoacetate results in decreased expression of PCBP4 mRNA
CTD
PMID:19753638
NCBI chr 8:107,092,688...107,103,276
Ensembl chr 8:107,093,013...107,103,276
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Ppp1r15a
protein phosphatase 1, regulatory subunit 15A
increases expression
ISO
bromoacetate results in increased expression of PPP1R15A mRNA
CTD
PMID:19753638
NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
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Prkdc
protein kinase, DNA-activated, catalytic subunit
increases expression
ISO
bromoacetate results in increased expression of PRKDC mRNA
CTD
PMID:19753638
NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
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Rad50
RAD50 double strand break repair protein
decreases expression
ISO
bromoacetate results in decreased expression of RAD50 mRNA
CTD
PMID:19753638
NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396
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Rad51
RAD51 recombinase
increases expression
ISO
bromoacetate results in increased expression of RAD51 mRNA
CTD
PMID:19753638
NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
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Rad9a
RAD9 checkpoint clamp component A
increases expression
ISO
bromoacetate results in increased expression of RAD9A mRNA
CTD
PMID:19753638
NCBI chr 1:201,488,511...201,553,582
Ensembl chr 1:201,487,136...201,553,608
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Rbbp8
RB binding protein 8, endonuclease
increases expression
ISO
bromoacetate results in increased expression of RBBP8 mRNA
CTD
PMID:19753638
NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846
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Sema4a
semaphorin 4A
increases expression
ISO
bromoacetate results in increased expression of SEMA4A mRNA
CTD
PMID:19753638
NCBI chr 2:173,896,432...173,917,903
Ensembl chr 2:173,896,439...173,914,442
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Tnf
tumor necrosis factor
decreases expression
ISO
bromoacetate results in decreased expression of TNF mRNA
CTD
PMID:19753638
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnfsf10
TNF superfamily member 10
decreases expression
ISO
bromoacetate results in decreased expression of TNFSF10 mRNA
CTD
PMID:19753638
NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
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Trex1
three prime repair exonuclease 1
decreases expression
ISO
bromoacetate results in decreased expression of TREX1 mRNA
CTD
PMID:19753638
NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796
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Tuba4a
tubulin, alpha 4A
increases acetylation
ISO
bromoacetate results in increased acetylation of TUBA4A protein
CTD
PMID:36174739
NCBI chr 9:76,709,617...76,714,327
Ensembl chr 9:76,709,614...76,713,918
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Xrcc2
X-ray repair cross complementing 2
decreases expression
ISO
bromoacetate results in decreased expression of XRCC2 mRNA
CTD
PMID:19753638
NCBI chr 4:9,423,873...9,502,980
Ensembl chr 4:9,423,898...9,442,482
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Xrcc3
X-ray repair cross complementing 3
decreases expression
ISO
bromoacetate results in decreased expression of XRCC3 mRNA
CTD
PMID:19753638
NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444
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