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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:3beta-(2-diethylaminoethoxy)androst-5-en-17-one hydrochloride
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Accession:CHEBI:190404 term browser browse the term
Definition:A hydrochloride obtained by reaction of 3beta-(2-diethylaminoethoxy)androst-5-en-17-one with one equivalent of hydrochloric acid. It is a cholesterol synthesis and transport inhibitor.
Synonyms:exact_synonym: 3beta-[2-(diethylamino)ethoxy]androst-5-en-17-one hydrochloride
 related_synonym: (3beta)-3-[2-(diethylamino)ethoxy]androst-5-en-17-one hydrochloride;   3beta-(2-diethylaminoethoxy)androst-5-en-17-one HCl;   Formula=C25H41NO2.ClH;   InChI=1S/C25H41NO2.ClH/c1-5-26(6-2)15-16-28-19-11-13-24(3)18(17-19)7-8-20-21-9-10-23(27)25(21,4)14-12-22(20)24;/h7,19-22H,5-6,8-17H2,1-4H3;1H/t19-,20-,21-,22-,24-,25-;/m0./s1;   InChIKey=GZFYZYBWLCYBMI-MYZJJQSMSA-N;   N,N-diethyl-2-[(17-oxoandrost-5-en-3beta-yl)oxy]ethanaminium chloride;   SMILES=Cl.[H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OCCN(CC)CC;   U 18666A;   U-18,666A;   U18666A
 xref: CAS:3039-71-2;   Chemspider:8129692
 xref_mesh: MESH:C006261
 xref: PMID:12622792;   PMID:16149744;   PMID:16771828;   PMID:18855586;   PMID:19158313;   PMID:19220841;   PMID:19440746;   PMID:22146564;   PMID:23250759;   PMID:25181483;   PMID:25688009;   PMID:26340949;   PMID:26344921;   PMID:26646182;   PMID:26815033;   PMID:27671775;   PMID:27707921;   PMID:28407359;   PMID:28722194;   PMID:28780424;   PMID:29530923;   PMID:29624387;   PMID:31174294;   PMID:31648726;   PMID:31963705;   PMID:33376205;   PMID:33403386;   PMID:33907281;   PMID:34047913;   PMID:34175669;   PMID:34502342;   PMID:34524402;   PMID:34671194;   PMID:34912322;   PMID:34919035;   PMID:35223543;   PMID:35309938;   Patent:WO2010083445


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3beta-(2-diethylaminoethoxy)androst-5-en-17-one hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpc1 glypican 1 decreases degradation ISO 3-beta-(2-(diethylamino)ethoxy)androst-5-en-17-one results in decreased degradation of GPC1 protein CTD PMID:21642435 NCBI chr 9:93,396,234...93,424,047
Ensembl chr 9:93,396,234...93,424,047 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      biological role 19785
        antimicrobial agent 18104
          antiviral agent 11061
            3beta-(2-diethylaminoethoxy)androst-5-en-17-one hydrochloride 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      halogen 18659
                        chlorine atom 18434
                          chlorine molecular entity 18463
                            elemental chlorine 8516
                              monoatomic chlorine 8501
                                chloride 8501
                                  chloride salt 8510
                                    organic chloride salt 1083
                                      hydrochloride 721
                                        3beta-(2-diethylaminoethoxy)androst-5-en-17-one hydrochloride 1
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