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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dysidenin
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Accession:CHEBI:189706 term browser browse the term
Definition:A secondary carboxamide resulting from the formal condensation of the carboxy group of (4S)-5,5,5-trichloro-N-methyl-N-[(3S)-4,4,4-trichloro-3-methylbutanoyl]-L-leucine with the amino group of (1S)-1-(1,3-thiazol-2-yl)ethanamine. It is a marine metabolite initially isolated from the sponge dysidea herbacea.
Synonyms:exact_synonym: (4S)-5,5,5-trichloro-N(2)-methyl-N-[(1S)-1-(1,3-thiazol-2-yl)ethyl]-N(2)-[(3S)-4,4,4-trichloro-3-methylbutanoyl]-L-leucinamide
 related_synonym: (2S,4S)-5,5,5-trichloro-4-methyl-2-{methyl[(3S)-4,4,4-trichloro-3-methylbutanoyl]amino}-N-[(1S)-1-(1,3-thiazol-2-yl)ethyl]pentanamide;   Formula=C17H23Cl6N3O2S;   InChI=1S/C17H23Cl6N3O2S/c1-9(16(18,19)20)7-12(14(28)25-11(3)15-24-5-6-29-15)26(4)13(27)8-10(2)17(21,22)23/h5-6,9-12H,7-8H2,1-4H3,(H,25,28)/t9-,10-,11-,12-/m0/s1;   InChIKey=BFVRAKVNXYQMID-BJDJZHNGSA-N;   SMILES=C[C@@H](C[C@H](N(C)C(=O)C[C@H](C)C(Cl)(Cl)Cl)C(=O)N[C@@H](C)C1=NC=CS1)C(Cl)(Cl)Cl
 xref: CAS:65647-65-6;   Chemspider:8183181;   KNApSAcK:C00028226
 xref_mesh: MESH:C063771
 xref: PMID:10650102;   PMID:10990437;   PMID:11575943;   PMID:12488351;   PMID:2157965;   PMID:21698777;   PMID:33265937;   PMID:34940697;   PMID:8070394;   PMID:9382940;   Wikipedia:Dysidenin



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dysidenin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc5a5 solute carrier family 5 member 5 multiple interactions ISO dysidenin inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog]; dysidenin inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog]; dysidenin inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m] CTD PMID:12488351 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20072
    role 20024
      biological role 20023
        poison 18549
          toxin 15932
            dysidenin 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 20072
    subatomic particle 20071
      composite particle 20071
        hadron 20071
          baryon 20071
            nucleon 20071
              atomic nucleus 20071
                atom 20071
                  main group element atom 19971
                    p-block element atom 19971
                      carbon group element atom 19894
                        carbon atom 19887
                          organic molecular entity 19887
                            organic group 18965
                              organic divalent group 18951
                                organodiyl group 18951
                                  carbonyl group 18903
                                    carbonyl compound 18903
                                      carboxylic acid 18601
                                        carboacyl group 17713
                                          univalent carboacyl group 17713
                                            carbamoyl group 17552
                                              carboxamide 17552
                                                secondary carboxamide 573
                                                  dysidenin 1
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