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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dysidenin
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Accession:CHEBI:189706 term browser browse the term
Definition:A secondary carboxamide resulting from the formal condensation of the carboxy group of (4S)-5,5,5-trichloro-N-methyl-N-[(3S)-4,4,4-trichloro-3-methylbutanoyl]-L-leucine with the amino group of (1S)-1-(1,3-thiazol-2-yl)ethanamine. It is a marine metabolite initially isolated from the sponge dysidea herbacea.
Synonyms:exact_synonym: (4S)-5,5,5-trichloro-N(2)-methyl-N-[(1S)-1-(1,3-thiazol-2-yl)ethyl]-N(2)-[(3S)-4,4,4-trichloro-3-methylbutanoyl]-L-leucinamide
 related_synonym: (2S,4S)-5,5,5-trichloro-4-methyl-2-{methyl[(3S)-4,4,4-trichloro-3-methylbutanoyl]amino}-N-[(1S)-1-(1,3-thiazol-2-yl)ethyl]pentanamide;   Formula=C17H23Cl6N3O2S;   InChI=1S/C17H23Cl6N3O2S/c1-9(16(18,19)20)7-12(14(28)25-11(3)15-24-5-6-29-15)26(4)13(27)8-10(2)17(21,22)23/h5-6,9-12H,7-8H2,1-4H3,(H,25,28)/t9-,10-,11-,12-/m0/s1;   InChIKey=BFVRAKVNXYQMID-BJDJZHNGSA-N;   SMILES=C[C@@H](C[C@H](N(C)C(=O)C[C@H](C)C(Cl)(Cl)Cl)C(=O)N[C@@H](C)C1=NC=CS1)C(Cl)(Cl)Cl
 xref: CAS:65647-65-6;   Chemspider:8183181;   KNApSAcK:C00028226
 xref_mesh: MESH:C063771
 xref: PMID:10650102;   PMID:10990437;   PMID:11575943;   PMID:12488351;   PMID:2157965;   PMID:21698777;   PMID:33265937;   PMID:34940697;   PMID:8070394;   PMID:9382940;   Wikipedia:Dysidenin


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dysidenin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc5a5 solute carrier family 5 member 5 multiple interactions ISO dysidenin inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog]; dysidenin inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog]; dysidenin inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m] CTD PMID:12488351 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19921
    role 19896
      biological role 19894
        poison 18643
          toxin 15978
            dysidenin 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19921
    subatomic particle 19919
      composite particle 19919
        hadron 19919
          baryon 19919
            nucleon 19919
              atomic nucleus 19919
                atom 19919
                  main group element atom 19867
                    p-block element atom 19867
                      carbon group element atom 19812
                        carbon atom 19807
                          organic molecular entity 19807
                            organic group 18971
                              organic divalent group 18952
                                organodiyl group 18952
                                  carbonyl group 18905
                                    carbonyl compound 18905
                                      carboxylic acid 18622
                                        carboacyl group 17704
                                          univalent carboacyl group 17704
                                            carbamoyl group 17550
                                              carboxamide 17550
                                                secondary carboxamide 1195
                                                  dysidenin 1
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