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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:C28-steroid
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Accession:CHEBI:188921 term browser browse the term
Synonyms:related_synonym: Formula=C28H50;   InChI=1S/C28H50/c1-19(2)20(3)10-11-21(4)24-14-15-25-23-13-12-22-9-7-8-17-27(22,5)26(23)16-18-28(24,25)6/h19-26H,7-18H2,1-6H3;   InChIKey=WAAWMJYYKITCGF-UHFFFAOYSA-N;   SMILES=C1C2C3C(CCC2(C(C1)C(CCC(C(C)C)C)C)C)C4(C(CC3)CCCC4)C;   a C28-steroid
 xref: MetaCyc:C28-Steroids;   PMID:16460510



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6-oxocampestanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator decreases expression ISO 6-oxocampestanol results in decreased expression of BCL2 protein CTD PMID:32001316 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 affects expression ISO 6-oxocampestanol affects the expression of BCL2L1 protein CTD PMID:32001316 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bid BH3 interacting domain death agonist affects expression ISO 6-oxocampestanol affects the expression of BID protein CTD PMID:32001316 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO 6-oxocampestanol results in decreased expression of CCNB1 protein CTD PMID:32001316 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO 6-oxocampestanol results in increased expression of CDKN1A protein CTD PMID:32001316 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Esr1 estrogen receptor 1 increases expression ISO 6-oxocampestanol results in increased expression of ESR1 protein CTD PMID:32001316 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 affects localization ISO 6-oxocampestanol affects the localization of ESR2 protein CTD PMID:32001316 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Pgr progesterone receptor affects localization ISO 6-oxocampestanol affects the localization of PGR protein CTD PMID:32001316 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO 6-oxocampestanol results in increased expression of and results in increased phosphorylation of RB1 protein CTD PMID:32001316 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Tp53 tumor protein p53 increases expression ISO 6-oxocampestanol results in increased expression of TP53 protein CTD PMID:32001316 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19921
    chemical entity 19919
      atom 19919
        nonmetal atom 19856
          carbon atom 19807
            organic molecular entity 19807
              lipid 17903
                steroid 14701
                  C28-steroid 10
                    (22S)-22-hydroxy C28-steroid + 0
                    24-epicampesterol 0
                    3-epi-6-deoxocathasterone 0
                    5alpha-campestan-3-one 0
                    5alpha-campestane + 10
                    5beta-campestane 0
                    6-deoxycathasterone 0
                    6-oxocampestanol 10
                    6alpha-hydroxycampestanol 0
                    campestane + 10
                    campestanol + 10
                    campesterol + 0
                    cathasterone + 0
                    typhasterol + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19921
    subatomic particle 19919
      composite particle 19919
        hadron 19919
          baryon 19919
            nucleon 19919
              atomic nucleus 19919
                atom 19919
                  main group element atom 19867
                    p-block element atom 19867
                      carbon group element atom 19812
                        carbon atom 19807
                          organic molecular entity 19807
                            organic molecule 19764
                              organic cyclic compound 19572
                                organic polycyclic compound 17264
                                  steroid 14701
                                    C28-steroid 10
                                      (22S)-22-hydroxy C28-steroid + 0
                                      24-epicampesterol 0
                                      3-epi-6-deoxocathasterone 0
                                      5alpha-campestan-3-one 0
                                      5alpha-campestane + 10
                                      5beta-campestane 0
                                      6-deoxycathasterone 0
                                      6-oxocampestanol 10
                                      6alpha-hydroxycampestanol 0
                                      campestane + 10
                                      campestanol + 10
                                      campesterol + 0
                                      cathasterone + 0
                                      typhasterol + 0
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