CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: C28-steroid
Accession: CHEBI:188921
browse the term
Synonyms: related_synonym: Formula=C28H50; InChI=1S/C28H50/c1-19(2)20(3)10-11-21(4)24-14-15-25-23-13-12-22-9-7-8-17-27(22,5)26(23)16-18-28(24,25)6/h19-26H,7-18H2,1-6H3; InChIKey=WAAWMJYYKITCGF-UHFFFAOYSA-N; SMILES=C1C2C3C(CCC2(C(C1)C(CCC(C(C)C)C)C)C)C4(C(CC3)CCCC4)C; a C28-steroid
xref: MetaCyc:C28-Steroids; PMID:16460510
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Bcl2
BCL2, apoptosis regulator
decreases expression
ISO
6-oxocampestanol results in decreased expression of BCL2 protein
CTD
PMID:32001316
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bcl2l1
Bcl2-like 1
affects expression
ISO
6-oxocampestanol affects the expression of BCL2L1 protein
CTD
PMID:32001316
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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Bid
BH3 interacting domain death agonist
affects expression
ISO
6-oxocampestanol affects the expression of BID protein
CTD
PMID:32001316
NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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Ccnb1
cyclin B1
decreases expression
ISO
6-oxocampestanol results in decreased expression of CCNB1 protein
CTD
PMID:32001316
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
ISO
6-oxocampestanol results in increased expression of CDKN1A protein
CTD
PMID:32001316
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Esr1
estrogen receptor 1
increases expression
ISO
6-oxocampestanol results in increased expression of ESR1 protein
CTD
PMID:32001316
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Esr2
estrogen receptor 2
affects localization
ISO
6-oxocampestanol affects the localization of ESR2 protein
CTD
PMID:32001316
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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Pgr
progesterone receptor
affects localization
ISO
6-oxocampestanol affects the localization of PGR protein
CTD
PMID:32001316
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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Rb1
RB transcriptional corepressor 1
multiple interactions
ISO
6-oxocampestanol results in increased expression of and results in increased phosphorylation of RB1 protein
CTD
PMID:32001316
NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
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Tp53
tumor protein p53
increases expression
ISO
6-oxocampestanol results in increased expression of TP53 protein
CTD
PMID:32001316
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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