3-chloropropane-1,2-diol - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	3-chloropropane-1,2-diol	go back to main search page
Accession:	CHEBI:18721	browse the term
Definition:	A chloropropane-1,2-diol that is propane-1,2-diol substituted by a chloro group at position 3.
Synonyms:	related_synonym:	(RS)-3-chloro-1,2-propanediol; 1-chloro-2,3-propanediol; 3-Monochloro-1,2-propanediol; Formula=C3H7ClO2; InChI=1S/C3H7ClO2/c4-1-3(6)2-5/h3,5-6H,1-2H2; InChIKey=SSZWWUDQMAHNAQ-UHFFFAOYSA-N; SMILES=OCC(O)CCl; alpha-chlorohydrin; chlorodeoxyglycerol
	xref:	Beilstein:635684; CAS:96-24-2; Gmelin:68752; KEGG:C18676
	xref_mesh:	MESH:D000517
	xref:	PPDB:1231; UM-BBD_compID:c0078

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Genes (1827)

3-chloropropane-1,2-diol

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-2-macroglobulin

decreases expression

alpha-Chlorohydrin results in decreased expression of A2M mRNA

NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786

G

arylacetamide deacetylase

increases expression

alpha-Chlorohydrin results in increased expression of AADAC mRNA

NCBI chr 2:144,163,436...144,186,086
Ensembl chr 2:144,135,319...144,174,734

G

alpha- and gamma-adaptin binding protein

increases expression

alpha-Chlorohydrin results in increased expression of AAGAB protein

NCBI chr 8:64,083,343...64,121,903
Ensembl chr 8:64,083,380...64,121,900

G

alanyl-tRNA synthetase 1

increases expression

alpha-Chlorohydrin results in increased expression of AARS1 protein

NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147

G

alanyl-tRNA synthetase 2, mitochondrial

increases expression

alpha-Chlorohydrin results in increased expression of AARS2 protein

NCBI chr 9:15,484,639...15,496,116
Ensembl chr 9:15,297,531...15,496,090

G

aminoadipate-semialdehyde synthase

decreases expression

alpha-Chlorohydrin analog results in decreased expression of AASS protein; alpha-Chlorohydrin results in decreased expression of AASS protein

PMID:26597043 PMID:34915118

NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136

G

4-aminobutyrate aminotransferase

increases expression

alpha-Chlorohydrin results in increased expression of ABAT mRNA

NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835

G

ATP binding cassette subfamily A member 2

decreases expression

alpha-Chlorohydrin results in decreased expression of ABCA2 protein

NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537

G

ATP binding cassette subfamily A member 3

increases expression

alpha-Chlorohydrin results in increased expression of ABCA3 mRNA

NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745

G

ATP binding cassette subfamily B member 1A

decreases expression
increases expression

alpha-Chlorohydrin results in decreased expression of ABCB1 protein
alpha-Chlorohydrin results in increased expression of ABCB1A protein

PMID:17803981 PMID:34915118

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP binding cassette subfamily B member 6

decreases expression

alpha-Chlorohydrin results in decreased expression of ABCB6 protein

NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924

G

ATP binding cassette subfamily C member 2

increases expression

alpha-Chlorohydrin results in increased expression of ABCC2 protein

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily C member 3

increases expression

alpha-Chlorohydrin results in increased expression of ABCC3 protein

NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595

G

ATP binding cassette subfamily C member 4

increases expression

alpha-Chlorohydrin results in increased expression of ABCC4 mRNA; alpha-Chlorohydrin results in increased expression of ABCC4 protein

PMID:28522335 PMID:34915118

NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283

G

ATP binding cassette subfamily D member 2

decreases expression

alpha-Chlorohydrin results in decreased expression of ABCD2 mRNA

NCBI chr 7:122,263,034...122,311,642
Ensembl chr 7:122,263,032...122,311,642

G

ATP binding cassette subfamily F member 1

increases expression

alpha-Chlorohydrin results in increased expression of ABCF1 protein

NCBI chr20:2,802,519...2,815,433
Ensembl chr20:2,802,488...2,815,433

G

ATP binding cassette subfamily F member 3

decreases expression

alpha-Chlorohydrin analog results in decreased expression of ABCF3 protein; alpha-Chlorohydrin results in decreased expression of ABCF3 protein

NCBI chr11:80,340,476...80,352,211
Ensembl chr11:80,339,977...80,352,211

G

ATP binding cassette subfamily G member 1

decreases expression

alpha-Chlorohydrin results in decreased expression of ABCG1 mRNA

NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948

G

abhydrolase domain containing 13

increases expression

alpha-Chlorohydrin results in increased expression of ABHD13 protein

NCBI chr16:79,501,879...79,516,712
Ensembl chr16:79,501,727...79,516,748

G

abhydrolase domain containing 14A

decreases expression

alpha-Chlorohydrin results in decreased expression of ABHD14A protein

NCBI chr 8:107,079,139...107,089,004
Ensembl chr 8:107,079,144...107,086,985

G

abhydrolase domain containing 17C, depalmitoylase

increases expression

alpha-Chlorohydrin results in increased expression of ABHD17C mRNA

NCBI chr 1:138,084,632...138,125,595
Ensembl chr 1:138,084,634...138,125,595

G

abhydrolase domain containing 2, acylglycerol lipase

increases expression

alpha-Chlorohydrin results in increased expression of ABHD2 mRNA

NCBI chr 1:133,217,403...133,298,564
Ensembl chr 1:133,217,375...133,299,061

G

abhydrolase domain containing 4, N-acyl phospholipase B

increases expression

alpha-Chlorohydrin results in increased expression of ABHD4 protein

NCBI chr15:27,697,384...27,716,013
Ensembl chr15:27,704,113...27,716,966

G

abhydrolase domain containing 8

decreases expression

alpha-Chlorohydrin results in decreased expression of ABHD8 mRNA

NCBI chr16:18,144,464...18,151,201
Ensembl chr16:18,144,464...18,157,667

G

abl-interactor 1

increases expression

alpha-Chlorohydrin results in increased expression of ABI1 protein

NCBI chr17:85,098,837...85,179,829
Ensembl chr17:85,098,550...85,179,792

G

actin binding LIM protein family, member 3

increases expression

alpha-Chlorohydrin results in increased expression of ABLIM3 mRNA; alpha-Chlorohydrin results in increased expression of ABLIM3 protein

PMID:28522335 PMID:34915118

NCBI chr18:55,256,135...55,376,629
Ensembl chr18:55,257,583...55,376,380

G

ABR activator of RhoGEF and GTPase

decreases expression

alpha-Chlorohydrin results in decreased expression of ABR mRNA

NCBI chr10:61,262,516...61,461,331
Ensembl chr10:61,262,516...61,461,505

G

acetyl-CoA acyltransferase 1A

increases expression

alpha-Chlorohydrin results in increased expression of ACAA1A mRNA

NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624

G

acetyl-CoA acyltransferase 2

decreases expression

alpha-Chlorohydrin results in decreased expression of ACAA2 protein

NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249

G

acetyl-CoA carboxylase alpha

increases expression

alpha-Chlorohydrin results in increased expression of ACACA protein

NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457

G

acyl-CoA dehydrogenase medium chain

decreases expression
affects expression
increases expression

alpha-Chlorohydrin analog results in decreased expression of ACADM protein
alpha-Chlorohydrin affects the expression of ACADM protein
alpha-Chlorohydrin results in increased expression of ACADM mRNA

PMID:26597043 PMID:28522335

NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147

G

acyl-CoA dehydrogenase short chain

decreases expression

alpha-Chlorohydrin analog results in decreased expression of ACADS protein; alpha-Chlorohydrin results in decreased expression of ACADS protein

NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898

G

acetyl-CoA acetyltransferase 1

increases expression

alpha-Chlorohydrin analog results in increased expression of ACAT1 protein

NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855

G

angiotensin I converting enzyme

decreases expression

alpha-Chlorohydrin results in decreased expression of ACE mRNA

NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131

G

angiotensin converting enzyme 2

decreases expression

alpha-Chlorohydrin results in decreased expression of ACE2 mRNA

NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977

G

aminocarboxymuconate semialdehyde decarboxylase

decreases expression

alpha-Chlorohydrin results in decreased expression of ACMSD protein

NCBI chr13:39,200,412...39,245,954
Ensembl chr13:39,200,314...39,245,209

G

aconitase 1

decreases expression
affects expression
increases expression

alpha-Chlorohydrin analog results in decreased expression of ACO1 protein
alpha-Chlorohydrin affects the expression of ACO1 protein
alpha-Chlorohydrin results in increased expression of ACO1 mRNA

PMID:26597043 PMID:28522335

NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391

G

acyl-CoA thioesterase 12

decreases expression

alpha-Chlorohydrin results in decreased expression of ACOT12 protein

NCBI chr 2:22,986,867...23,027,538
Ensembl chr 2:22,986,626...23,027,536

G

acyl-CoA thioesterase 7

decreases expression

alpha-Chlorohydrin results in decreased expression of ACOT7 mRNA

NCBI chr 5:162,686,562...162,779,309
Ensembl chr 5:162,684,645...162,779,309

G

acyl-CoA thioesterase 9

decreases expression

alpha-Chlorohydrin results in decreased expression of ACOT9 mRNA

NCBI chr X:40,073,197...40,123,573
Ensembl chr X:40,064,810...40,123,559

G

acyl-CoA oxidase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of ACOX1 protein

NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232

G

acid phosphatase 6, lysophosphatidic

increases expression

alpha-Chlorohydrin results in increased expression of ACP6 protein

NCBI chr 2:184,711,975...184,733,067
Ensembl chr 2:184,711,619...184,733,017

G

acyl-CoA synthetase family member 2

decreases expression

alpha-Chlorohydrin results in decreased expression of ACSF2 protein

NCBI chr10:79,504,510...79,546,714
Ensembl chr10:79,504,511...79,546,673

G

acyl-CoA synthetase long-chain family member 1

increases expression
decreases expression

alpha-Chlorohydrin results in increased expression of ACSL1 protein
alpha-Chlorohydrin analog results in decreased expression of ACSL1 protein

NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541

G

acyl-CoA synthetase long-chain family member 3

increases expression

alpha-Chlorohydrin results in increased expression of ACSL3 protein

NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627

G

acyl-CoA synthetase long-chain family member 4

increases expression

alpha-Chlorohydrin results in increased expression of ACSL4 protein

NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427

G

acyl-CoA synthetase long-chain family member 5

decreases expression

alpha-Chlorohydrin results in decreased expression of ACSL5 mRNA

NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607

G

acyl-CoA synthetase medium-chain family member 3

decreases expression
multiple interactions

alpha-Chlorohydrin results in decreased expression of ACSM3 mRNA
[alpha-Chlorohydrin co-treated with glycidol] results in decreased expression of ACSM3 mRNA

PMID:28522335 PMID:33187795

NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184

G

acyl-CoA synthetase medium-chain family member 5

increases expression

alpha-Chlorohydrin results in increased expression of ACSM5 protein

NCBI chr 1:173,870,873...173,896,838
Ensembl chr 1:173,863,041...173,898,588

G

acyl-CoA synthetase short-chain family member 3

increases expression

alpha-Chlorohydrin results in increased expression of ACSS3 mRNA

NCBI chr 7:42,241,261...42,450,209
Ensembl chr 7:42,242,652...42,450,230

G

actin, beta

decreases expression
affects expression

alpha-Chlorohydrin analog results in decreased expression of ACTB protein; alpha-Chlorohydrin results in decreased expression of ACTB protein
alpha-Chlorohydrin affects the expression of ACTB protein; alpha-Chlorohydrin analog affects the expression of ACTB protein

PMID:26072098 PMID:26597043

NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877

G

actinin, alpha 1

increases expression

alpha-Chlorohydrin results in increased expression of ACTN1 mRNA; alpha-Chlorohydrin results in increased expression of ACTN1 protein

PMID:26072098 PMID:28522335

NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251

G

actinin alpha 4

increases expression

alpha-Chlorohydrin results in increased expression of ACTN4 protein

NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847

G

aminoacylase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of ACY1 protein

NCBI chr 8:107,072,354...107,077,756
Ensembl chr 8:107,072,358...107,077,682

G

aminoacylase 3

decreases expression

alpha-Chlorohydrin results in decreased expression of ACY3 protein

NCBI chr 1:201,279,751...201,285,803
Ensembl chr 1:201,279,851...201,283,175

G

ADAM metallopeptidase domain 1a

decreases expression

alpha-Chlorohydrin results in decreased expression of ADAM1A mRNA

NCBI chr12:35,017,433...35,020,300
Ensembl chr12:35,017,315...35,020,311

G

ADAM metallopeptidase domain 23

increases expression

alpha-Chlorohydrin results in increased expression of ADAM23 mRNA

NCBI chr 9:64,862,649...65,009,718
Ensembl chr 9:64,862,878...65,006,515

G

ArfGAP with dual PH domains 2

increases expression

alpha-Chlorohydrin results in increased expression of ADAP2 mRNA

NCBI chr10:65,138,006...65,166,147
Ensembl chr10:65,138,020...65,165,604

G

adenosine deaminase, RNA-specific

increases expression

alpha-Chlorohydrin results in increased expression of ADAR protein

NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282

G

alcohol dehydrogenase 1C (class I), gamma polypeptide

decreases expression

alpha-Chlorohydrin results in decreased expression of ADH1 protein

NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892

G

ADRM1 26S proteasome ubiquitin receptor

decreases expression

alpha-Chlorohydrin results in decreased expression of ADRM1 protein

NCBI chr 3:167,265,435...167,270,197
Ensembl chr 3:167,265,296...167,270,195

G

actin filament associated protein 1

affects expression

alpha-Chlorohydrin affects the expression of AFAP1 mRNA

NCBI chr14:74,743,322...74,856,300
Ensembl chr14:74,743,320...74,856,263

G

AFG2 AAA ATPase homolog A

increases expression

alpha-Chlorohydrin results in increased expression of AFG2A protein

NCBI chr 2:120,306,417...120,497,707
Ensembl chr 2:120,306,412...120,497,705

G

AFG3 like matrix AAA peptidase subunit 2

increases expression

alpha-Chlorohydrin results in increased expression of AFG3L2 protein

NCBI chr18:60,954,268...60,999,110
Ensembl chr18:60,954,268...60,999,110

G

arylformamidase

decreases expression

alpha-Chlorohydrin results in decreased expression of AFMID mRNA

NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718

G

aftiphilin

increases expression

alpha-Chlorohydrin results in increased expression of AFTPH protein

NCBI chr14:94,871,429...94,925,625
Ensembl chr14:94,871,429...94,925,376

G

advanced glycosylation end product-specific receptor

decreases expression

alpha-Chlorohydrin results in decreased expression of H3C8 mRNA

NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078

G

1-acylglycerol-3-phosphate O-acyltransferase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of AGPAT1 protein

NCBI chr20:4,135,955...4,144,880
Ensembl chr20:4,135,957...4,145,278

G

agrin

decreases expression

alpha-Chlorohydrin results in decreased expression of AGRN mRNA

NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003

G

AHNAK nucleoprotein

affects expression

alpha-Chlorohydrin affects the expression of AHNAK mRNA

NCBI chr 1:205,882,225...205,970,934
Ensembl chr 1:205,882,273...205,970,926

G

activation-induced cytidine deaminase

increases expression

alpha-Chlorohydrin results in increased expression of APOBEC3B mRNA

NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972

G

apoptosis inducing factor, mitochondria associated 1

decreases expression
increases expression

alpha-Chlorohydrin results in decreased expression of AIFM1 mRNA
alpha-Chlorohydrin results in increased expression of AIFM1 protein

PMID:28070108 PMID:34461274

NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256

G

aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

increases expression

alpha-Chlorohydrin results in increased expression of AIMP1 protein

NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728

G

aminoacyl tRNA synthetase complex-interacting multifunctional protein 2

increases expression

alpha-Chlorohydrin results in increased expression of AIMP2 protein

NCBI chr12:10,701,194...10,710,772
Ensembl chr12:10,701,194...10,710,769

G

aryl-hydrocarbon receptor-interacting protein

decreases expression

alpha-Chlorohydrin analog results in decreased expression of AIP protein

NCBI chr 1:201,408,002...201,419,220
Ensembl chr 1:201,407,288...201,419,122

G

adenylate kinase 1

increases expression

alpha-Chlorohydrin results in increased expression of AK1 protein

NCBI chr 3:15,912,431...15,923,045
Ensembl chr 3:15,912,485...15,923,041

G

A-kinase anchoring protein 1

decreases expression

alpha-Chlorohydrin results in decreased expression of AKAP1 mRNA

NCBI chr10:73,621,021...73,654,123
Ensembl chr10:73,621,883...73,653,896

G

A-kinase anchoring protein 10

increases expression

alpha-Chlorohydrin results in increased expression of AKAP10 protein

NCBI chr10:46,545,371...46,608,730
Ensembl chr10:46,551,532...46,608,769

G

A-kinase anchoring protein 17A

increases expression

alpha-Chlorohydrin results in increased expression of AKAP17A protein

NCBI chr12:16,310,427...16,315,166
Ensembl chr12:16,310,437...16,314,479

G

A-kinase anchoring protein 9

increases expression

alpha-Chlorohydrin results in increased expression of AKAP9 protein

NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606

G

aldo-keto reductase family 1 member A1

decreases expression

alpha-Chlorohydrin analog results in decreased expression of AKR1A1 protein; alpha-Chlorohydrin results in decreased expression of AKR1A1 protein

NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674

G

aldo-keto reductase family 1 member B1

decreases expression
increases expression

alpha-Chlorohydrin results in decreased expression of AKR1B1 mRNA
alpha-Chlorohydrin results in increased expression of AKR1B1 protein

PMID:28522335 PMID:34915118

NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157

G

aldo-keto reductase family 1 member B10

increases expression

alpha-Chlorohydrin results in increased expression of AKR1B10 mRNA

NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852

G

aldo-keto reductase family 1, member B7

increases expression

alpha-Chlorohydrin results in increased expression of AKR1B7 protein

NCBI chr 4:63,053,560...63,100,934
Ensembl chr 4:63,076,800...63,089,502

G

aldo-keto reductase family 1, member C3

decreases expression

alpha-Chlorohydrin results in decreased expression of AKR1C3 protein

NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873

G

aldo-keto reductase family 1, member D1

affects expression

alpha-Chlorohydrin analog affects the expression of AKR1D1 protein

NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372

G

aldo-keto reductase family 7, member A2

decreases expression

alpha-Chlorohydrin results in decreased expression of AKR7A2 protein

NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909

G

aldo-keto reductase family 7 member A3

increases expression

alpha-Chlorohydrin results in increased expression of AKR7A3 protein

NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394

G

AKT serine/threonine kinase 1

increases expression

alpha-Chlorohydrin results in increased expression of AKT1 protein

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

aminolevulinate dehydratase

decreases expression

alpha-Chlorohydrin analog results in decreased expression of ALAD protein; alpha-Chlorohydrin results in decreased expression of ALAD protein

NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474

G

albumin

increases expression

alpha-Chlorohydrin analog results in increased expression of ALB protein; alpha-Chlorohydrin results in increased expression of ALB protein

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

aldehyde dehydrogenase 16 family, member A1

decreases expression

alpha-Chlorohydrin analog results in decreased expression of ALDH16A1 protein

NCBI chr 1:95,626,727...95,639,808
Ensembl chr 1:95,613,558...95,640,131

G

aldehyde dehydrogenase 1 family, member A1

increases expression
decreases expression

alpha-Chlorohydrin results in increased expression of ALDH1A1 mRNA; alpha-Chlorohydrin results in increased expression of ALDH1A1 protein
alpha-Chlorohydrin results in decreased expression of ALDH1A1 mRNA

PMID:26072098 PMID:28522335 PMID:35063618

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

aldehyde dehydrogenase 3 family, member A2

increases expression

alpha-Chlorohydrin analog results in increased expression of ALDH3A2 protein; alpha-Chlorohydrin results in increased expression of ALDH3A2 protein

NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281

G

aldehyde dehydrogenase 4 family, member A1

decreases expression

alpha-Chlorohydrin results in decreased expression of ALDH4A1 mRNA

NCBI chr 5:151,880,002...151,905,491
Ensembl chr 5:151,830,701...151,925,345

G

aldehyde dehydrogenase 6 family, member A1

affects expression

alpha-Chlorohydrin affects the expression of ALDH6A1 protein; alpha-Chlorohydrin analog affects the expression of ALDH6A1 protein

NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656

G

aldehyde dehydrogenase 7 family, member A1

increases expression

alpha-Chlorohydrin results in increased expression of ALDH7A1 mRNA

NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193

G

aldehyde dehydrogenase 9 family, member A1

affects expression
decreases expression

alpha-Chlorohydrin analog affects the expression of ALDH9A1 protein
alpha-Chlorohydrin results in decreased expression of ALDH9A1 protein

PMID:26072098 PMID:26597043

NCBI chr13:79,505,738...79,522,539
Ensembl chr13:79,505,695...79,540,568

G

aldolase, fructose-bisphosphate A

increases expression

alpha-Chlorohydrin results in increased expression of ALDOA protein

NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182

G

alsin Rho guanine nucleotide exchange factor ALS2

increases expression

alpha-Chlorohydrin results in increased expression of ALS2 protein

NCBI chr 9:60,613,182...60,686,394
Ensembl chr 9:60,613,167...60,670,737

G

alpha-methylacyl-CoA racemase

affects expression
decreases expression

alpha-Chlorohydrin analog affects the expression of AMACR protein
alpha-Chlorohydrin results in decreased expression of AMACR protein

NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255

G

amidohydrolase domain containing 2

increases expression

alpha-Chlorohydrin results in increased expression of AMDHD2 protein

NCBI chr10:13,187,579...13,196,148
Ensembl chr10:13,187,578...13,196,095

G

adenosine monophosphate deaminase 3

decreases expression
increases expression

alpha-Chlorohydrin results in decreased expression of AMPD3 mRNA
alpha-Chlorohydrin results in increased expression of AMPD3 protein

PMID:28522335 PMID:34915118

NCBI chr 1:164,884,823...164,929,899
Ensembl chr 1:164,885,320...164,929,887

G

aminomethyltransferase

increases expression

alpha-Chlorohydrin results in increased expression of AMT mRNA

NCBI chr 8:108,981,620...108,988,127
Ensembl chr 8:108,976,472...108,988,126

G

angiopoietin 1

increases expression

alpha-Chlorohydrin results in increased expression of ANGPT1 mRNA

NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067

G

angiopoietin like 7

increases expression

alpha-Chlorohydrin results in increased expression of ANGPTL7 mRNA

NCBI chr 5:158,932,096...158,937,281
Ensembl chr 5:158,932,794...158,937,324

G

ankyrin repeat and MYND domain containing 2

increases expression

alpha-Chlorohydrin results in increased expression of ANKMY2 protein

NCBI chr 6:52,888,959...52,930,343
Ensembl chr 6:52,888,963...52,930,394

G

ankyrin repeat domain 17

increases expression

alpha-Chlorohydrin results in increased expression of ANKRD17 protein

NCBI chr14:17,723,239...17,861,841
Ensembl chr14:17,721,932...17,862,617

G

ankyrin repeat domain 33B

increases expression

alpha-Chlorohydrin results in increased expression of ANKRD33B mRNA

NCBI chr 2:82,277,604...82,359,420
Ensembl chr 2:82,283,108...82,358,872

G

ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1

increases expression

alpha-Chlorohydrin results in increased expression of ANKZF1 protein

NCBI chr 9:76,688,194...76,695,162
Ensembl chr 9:76,688,194...76,696,469

G

anoctamin 1

increases expression

alpha-Chlorohydrin results in increased expression of ANO1 mRNA

NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069

G

acidic nuclear phosphoprotein 32 family member E

increases expression

alpha-Chlorohydrin results in increased expression of ANP32E protein

NCBI chr 2:183,472,600...183,489,057
Ensembl chr 2:183,472,609...183,489,054

G

annexin A1

increases expression

alpha-Chlorohydrin results in increased expression of ANXA1 protein

NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343

G

annexin A2

increases expression
decreases expression

alpha-Chlorohydrin results in increased expression of ANXA2 protein
alpha-Chlorohydrin results in decreased expression of ANXA2 mRNA

PMID:26072098 PMID:28522335 PMID:34915118

NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658

G

annexin A4

increases expression

alpha-Chlorohydrin results in increased expression of ANXA4 protein

NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161

G

annexin A7

increases expression

alpha-Chlorohydrin results in increased expression of ANXA7 protein

NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385

G

aldehyde oxidase 1

increases expression

alpha-Chlorohydrin results in increased expression of AOX1 protein

NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770

G

adaptor related protein complex 1 subunit gamma 2

increases expression

alpha-Chlorohydrin results in increased expression of AP1G2 protein

NCBI chr15:28,571,571...28,579,421
Ensembl chr15:28,571,568...28,589,004

G

adaptor related protein complex 3 subunit beta 2

decreases expression

alpha-Chlorohydrin results in decreased expression of AP3B2 mRNA

NCBI chr 1:135,412,580...135,445,191
Ensembl chr 1:135,412,580...135,445,191

G

adaptor related protein complex 4 subunit epsilon 1

increases expression

alpha-Chlorohydrin results in increased expression of AP4E1 protein

NCBI chr 3:114,272,997...114,339,484
Ensembl chr 3:114,272,956...114,336,752

G

adaptor related protein complex 5 subunit beta 1

increases expression

alpha-Chlorohydrin results in increased expression of AP5B1 protein

NCBI chr 1:202,876,272...202,880,303
Ensembl chr 1:202,876,272...202,880,289

G

adaptor related protein complex 5 subunit sigma 1

increases expression

alpha-Chlorohydrin results in increased expression of AP5S1 protein

NCBI chr 3:118,429,618...118,432,929
Ensembl chr 3:118,429,637...118,432,926

G

apoptotic peptidase activating factor 1

multiple interactions
increases expression

4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of APAF1 protein]; Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of APAF1 mRNA]
alpha-Chlorohydrin results in increased expression of APAF1 mRNA; alpha-Chlorohydrin results in increased expression of APAF1 protein
3-methyladenine inhibits the reaction [Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of APAF1 protein]]; Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of APAF1 protein]

PMID:30107153 PMID:33651226 PMID:35149085

NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540

G

amyloid beta precursor protein binding family B member 1 interacting protein

decreases expression

alpha-Chlorohydrin results in decreased expression of APBB1IP mRNA

NCBI chr17:84,941,404...85,033,020
Ensembl chr17:84,982,243...85,033,010

G

amyloid P component, serum

increases expression

alpha-Chlorohydrin results in increased expression of APCS mRNA

NCBI chr13:85,373,219...85,374,195
Ensembl chr13:85,373,220...85,374,298

G

acylaminoacyl-peptide hydrolase

decreases expression

alpha-Chlorohydrin analog results in decreased expression of APEH protein; alpha-Chlorohydrin results in decreased expression of APEH protein

NCBI chr 8:108,773,791...108,782,903
Ensembl chr 8:108,773,794...108,782,933

G

apolipoprotein A2

increases expression

alpha-Chlorohydrin results in increased expression of APOA2 protein

NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355

G

apolipoprotein B

increases expression

alpha-Chlorohydrin results in increased expression of APOB mRNA

NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497

G

apolipoprotein E

increases expression

alpha-Chlorohydrin analog results in increased expression of APOE protein; alpha-Chlorohydrin results in increased expression of APOE protein

PMID:26597043 PMID:34915118

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

G

amyloid beta precursor protein

decreases expression

alpha-Chlorohydrin results in decreased expression of APP mRNA

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

G

aquaporin 6

decreases expression

alpha-Chlorohydrin results in decreased expression of AQP6 mRNA

NCBI chr 7:130,732,216...130,735,149
Ensembl chr 7:130,633,579...130,735,194
Ensembl chr 7:130,633,579...130,735,194

G

aquaporin 7

increases expression

alpha-Chlorohydrin results in increased expression of AQP7 protein

NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642

G

androgen receptor

decreases expression

alpha-Chlorohydrin results in decreased expression of AR protein

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

ARF GTPase activating protein 1

increases expression

alpha-Chlorohydrin results in increased expression of ARFGAP1 protein

NCBI chr 3:168,084,560...168,099,948
Ensembl chr 3:168,084,614...168,099,933

G

arginase 1

decreases expression
increases expression

alpha-Chlorohydrin analog results in decreased expression of ARG1 protein
alpha-Chlorohydrin results in increased expression of ARG1 protein

PMID:26597043 PMID:34915118

NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422

G

Rho GDP dissociation inhibitor beta

increases expression

alpha-Chlorohydrin results in increased expression of ARHGDIB protein

NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658

G

Rho guanine nucleotide exchange factor 5

increases expression

alpha-Chlorohydrin results in increased expression of ARHGEF5 protein

NCBI chr 4:72,087,205...72,112,316
Ensembl chr 4:72,087,247...72,111,254

G

armadillo repeat containing 6

increases expression

alpha-Chlorohydrin results in increased expression of ARMC6 protein

NCBI chr16:19,191,106...19,201,528
Ensembl chr16:19,191,093...19,206,047

G

armadillo repeat containing 9

increases expression

alpha-Chlorohydrin results in increased expression of ARMC9 protein

NCBI chr 9:86,802,791...86,928,611
Ensembl chr 9:86,802,868...86,928,860

G

actin related protein 2/3 complex, subunit 1B

increases expression

alpha-Chlorohydrin results in increased expression of ARPC1B protein

NCBI chr12:9,482,176...9,495,772
Ensembl chr12:9,480,831...9,495,747

G

actin related protein 2/3 complex, subunit 4

increases expression

alpha-Chlorohydrin results in increased expression of ARPC4 mRNA

NCBI chr 4:146,522,255...146,532,784
Ensembl chr 4:146,522,176...146,532,785

G

arrestin domain containing 2

decreases expression

alpha-Chlorohydrin results in decreased expression of ARRDC2 mRNA

NCBI chr16:18,601,897...18,606,029
Ensembl chr16:18,601,897...18,606,029

G

arylsulfatase A

increases expression

alpha-Chlorohydrin results in increased expression of ARSA protein

NCBI chr 7:120,542,788...120,547,577
Ensembl chr 7:120,543,362...120,548,783

G

arsenite methyltransferase

increases expression

alpha-Chlorohydrin analog results in increased expression of AS3MT protein

NCBI chr 1:245,595,939...245,628,921
Ensembl chr 1:245,596,108...245,627,872

G

activating signal cointegrator 1 complex subunit 1

increases expression

alpha-Chlorohydrin results in increased expression of ASCC1 protein

NCBI chr20:27,941,053...28,031,272
Ensembl chr20:27,941,283...28,031,272

G

argininosuccinate lyase

increases expression

alpha-Chlorohydrin results in increased expression of ASL mRNA; alpha-Chlorohydrin results in increased expression of ASL protein

PMID:26597043 PMID:28522335

NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662

G

asparagine synthetase (glutamine-hydrolyzing)

increases expression

alpha-Chlorohydrin results in increased expression of ASNS protein

NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423

G

aspartate dehydrogenase domain containing

decreases expression

alpha-Chlorohydrin results in decreased expression of ASPDH protein

NCBI chr 1:94,956,327...94,960,722
Ensembl chr 1:94,958,316...94,960,722

G

ASPSCR1 tether for SLC2A4, UBX domain containing

increases expression

alpha-Chlorohydrin results in increased expression of ASPSCR1 protein

NCBI chr10:105,952,215...105,990,059
Ensembl chr10:105,952,227...105,989,904

G

argininosuccinate synthase 1

increases expression

alpha-Chlorohydrin results in increased expression of ASS1 mRNA

NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903

G

ATPase family, AAA domain containing 1

increases expression

alpha-Chlorohydrin results in increased expression of ATAD1 protein

NCBI chr 1:230,544,227...230,610,524
Ensembl chr 1:230,544,047...230,596,548

G

ATPase family, AAA domain containing 3A

increases expression

alpha-Chlorohydrin results in increased expression of ATAD3A protein

NCBI chr 5:166,350,302...166,370,492
Ensembl chr 5:166,350,304...166,370,482

G

activating transcription factor 4

multiple interactions
increases expression

4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of ATF4 protein]

NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446

G

activating transcription factor 6

multiple interactions

alpha-Chlorohydrin results in increased expression of and affects the cleavage of ATF6 protein
[4-phenylbutyric acid co-treated with alpha-Chlorohydrin] results in decreased expression of ATF6 protein

NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177

G

autophagy related 12

increases expression

alpha-Chlorohydrin results in increased expression of ATG12 protein

NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418

G

autophagy related 13

increases expression

alpha-Chlorohydrin results in increased expression of ATG13 protein

NCBI chr 3:77,647,069...77,681,028
Ensembl chr 3:77,645,790...77,681,043

G

autophagy related 16-like 1

increases expression

alpha-Chlorohydrin results in increased expression of ATG16L1 protein

NCBI chr 9:88,420,737...88,457,530
Ensembl chr 9:88,422,038...88,457,529

G

autophagy related 5

increases expression

alpha-Chlorohydrin results in increased expression of ATG5 protein

NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209

G

ATPase 13A1

increases expression

alpha-Chlorohydrin results in increased expression of ATP13A1 protein

NCBI chr16:19,615,156...19,631,546
Ensembl chr16:19,615,160...19,631,214

G

ATPase Na+/K+ transporting subunit beta 1

decreases expression

alpha-Chlorohydrin results in decreased expression of ATP1B1 mRNA

NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459

G

ATP synthase F1 subunit alpha

increases expression

alpha-Chlorohydrin analog results in increased expression of ATP5F1A protein

NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794

G

ATP synthase membrane subunit K

decreases expression

alpha-Chlorohydrin results in decreased expression of ATP5MK mRNA

NCBI chr 1:245,973,910...245,980,702
Ensembl chr 1:245,973,914...245,980,761
Ensembl chr10:245,973,914...245,980,761

G

ATPase H+ transporting accessory protein 2

increases expression

alpha-Chlorohydrin results in increased expression of ATP6AP2 mRNA

NCBI chr X:10,183,983...10,210,948
Ensembl chr X:10,183,068...10,210,918

G

ATPase H+ transporting V1 subunit A

decreases expression
multiple interactions

alpha-Chlorohydrin results in decreased expression of ATP6V1A mRNA
ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of ATP6V1A mRNA]

PMID:32702505 PMID:34812491

NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694

G

ATPase H+ transporting V1 subunit B2

decreases expression
increases expression
multiple interactions

alpha-Chlorohydrin results in decreased expression of ATP6V1B2 mRNA; alpha-Chlorohydrin results in decreased expression of ATP6V1B2 protein
alpha-Chlorohydrin results in increased expression of ATP6V1B2 mRNA
ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of ATP6V1B2 mRNA]

PMID:27732882 PMID:28522335 PMID:32702505 PMID:34812491

NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745

G

ATPase H+ transporting V1 subunit G3

decreases expression

alpha-Chlorohydrin results in decreased expression of ATP6V1G3 mRNA

NCBI chr13:49,800,256...49,825,247
Ensembl chr13:49,794,222...49,825,247

G

ATPase phospholipid transporting 8A1

increases expression

alpha-Chlorohydrin results in increased expression of ATP8A1 mRNA

NCBI chr14:40,315,013...40,557,572
Ensembl chr14:40,315,049...40,554,611

G

ATPase phospholipid transporting 8B2

decreases expression

alpha-Chlorohydrin results in decreased expression of ATP8B2 protein

NCBI chr 2:175,378,514...175,402,265
Ensembl chr 2:175,378,517...175,401,883

G

all-trans retinoic acid-induced differentiation factor

decreases expression

alpha-Chlorohydrin results in decreased expression of ATRAID mRNA

NCBI chr 6:25,315,236...25,319,821

G

AUP1, lipid droplet regulating VLDL assembly factor

increases expression

alpha-Chlorohydrin results in increased expression of AUP1 protein

NCBI chr 4:115,560,274...115,563,346
Ensembl chr 4:115,560,261...115,563,346

G

arginine vasopressin receptor 1A

increases expression

alpha-Chlorohydrin results in increased expression of AVPR1A mRNA

NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215

G

beta-1,3-glucuronyltransferase 1

increases expression

alpha-Chlorohydrin results in increased expression of B3GAT1 mRNA

NCBI chr 8:25,087,123...25,114,692
Ensembl chr 8:25,087,547...25,113,395

G

beta-1,4-galactosyltransferase 5

increases expression

alpha-Chlorohydrin results in increased expression of B4GALT5 mRNA

NCBI chr 3:156,018,056...156,033,983
Ensembl chr 3:156,018,053...156,070,074

G

bile acid CoA:amino acid N-acyltransferase

increases expression

alpha-Chlorohydrin analog results in increased expression of BAAT protein
alpha-Chlorohydrin results in increased expression of BAAT mRNA

PMID:26597043 PMID:33187795

NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685

G

BAG cochaperone 2

increases expression

alpha-Chlorohydrin results in increased expression of BAG2 protein

NCBI chr 9:35,970,033...35,980,677
Ensembl chr 9:35,970,033...35,980,721

G

BAR/IMD domain containing adaptor protein 2 like 1

increases expression

alpha-Chlorohydrin results in increased expression of BAIAP2L1 mRNA

NCBI chr12:10,250,434...10,339,937
Ensembl chr12:10,250,473...10,339,928

G

barrier to autointegration nuclear assembly factor 1

increases expression

alpha-Chlorohydrin results in increased expression of BANF1 protein

NCBI chr 1:202,672,170...202,674,215
Ensembl chr 1:202,671,305...202,674,188

G

Btg3 associated nuclear protein

increases expression

alpha-Chlorohydrin results in increased expression of BANP mRNA

NCBI chr19:50,007,710...50,082,742
Ensembl chr19:50,007,881...50,082,738

G

BCL2 associated X, apoptosis regulator

increases expression
multiple interactions

alpha-Chlorohydrin results in increased expression of BAX mRNA; alpha-Chlorohydrin results in increased expression of BAX protein
4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of BAX protein]; Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of BAX mRNA]; Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of BAX protein]

PMID:27732882 PMID:28070108 PMID:30107153 PMID:33651226 PMID:34915118

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

BCAR1 scaffold protein, Cas family member

increases expression

alpha-Chlorohydrin results in increased expression of BCAR1 protein

NCBI chr19:39,679,215...39,713,907
Ensembl chr19:39,679,204...39,713,907

G

BCAS3, microtubule associated cell migration factor

increases expression

alpha-Chlorohydrin results in increased expression of BCAS3 protein

NCBI chr10:70,213,710...70,673,080
Ensembl chr10:70,214,098...70,673,080

G

branched chain keto acid dehydrogenase E1 subunit alpha

decreases expression

alpha-Chlorohydrin analog results in decreased expression of BCKDHA protein; alpha-Chlorohydrin results in decreased expression of BCKDHA protein

NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862

G

BCL2, apoptosis regulator

decreases expression
multiple interactions

alpha-Chlorohydrin results in decreased expression of BCL2 mRNA; alpha-Chlorohydrin results in decreased expression of BCL2 protein
4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in decreased expression of BCL2 protein]; Apigenin inhibits the reaction [alpha-Chlorohydrin results in decreased expression of BCL2 mRNA]

PMID:27732882 PMID:28070108 PMID:30107153 PMID:33651226 PMID:34915118

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

Bcl2-like 14

increases expression

alpha-Chlorohydrin results in increased expression of BCL2L14 protein

NCBI chr 4:167,217,561...167,258,723
Ensembl chr 4:167,219,871...167,258,086

G

betaine-homocysteine S-methyltransferase

decreases expression

alpha-Chlorohydrin analog results in decreased expression of BHMT protein; alpha-Chlorohydrin results in decreased expression of BHMT protein

PMID:26597043 PMID:34915118

NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742

G

BicC family RNA binding protein 1

increases expression

alpha-Chlorohydrin results in increased expression of BICC1 protein

NCBI chr20:17,449,639...17,686,775
Ensembl chr20:17,449,560...17,686,776

G

BH3 interacting domain death agonist

increases expression

alpha-Chlorohydrin results in increased expression of BID mRNA

NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720

G

BCL2-interacting killer

increases expression

alpha-Chlorohydrin results in increased expression of BIK mRNA

NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296

G

baculoviral IAP repeat-containing 3

decreases expression

alpha-Chlorohydrin results in decreased expression of BIRC3 mRNA

NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802

G

bridge-like lipid transfer protein family member 3B

increases expression

alpha-Chlorohydrin results in increased expression of BLTP3B protein

NCBI chr 7:24,181,635...24,261,720
Ensembl chr 7:24,181,644...24,261,720

G

basic helix-loop-helix ARNT like 1

decreases expression

alpha-Chlorohydrin results in decreased expression of BMAL1 mRNA

NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231

G

bone morphogenetic protein 3

decreases expression

alpha-Chlorohydrin results in decreased expression of BMP3 mRNA

NCBI chr14:10,712,489...10,737,153
Ensembl chr14:10,712,489...10,737,153

G

BOP1 ribosomal biogenesis factor

increases expression

alpha-Chlorohydrin results in increased expression of BOP1 protein

NCBI chr 7:108,172,062...108,195,875
Ensembl chr 7:108,172,066...108,195,931

G

BLOC-1 related complex subunit 8

increases expression

alpha-Chlorohydrin results in increased expression of BORCS8 mRNA

NCBI chr16:19,274,305...19,280,969
Ensembl chr16:19,274,023...19,280,339

G

biphenyl hydrolase like

decreases expression

alpha-Chlorohydrin results in decreased expression of BPHL protein

NCBI chr17:30,800,939...30,837,277
Ensembl chr17:30,799,629...30,837,288

G

BPI fold containing family A, member 2F

decreases expression

alpha-Chlorohydrin results in decreased expression of BPIFA2F mRNA

NCBI chr 3:142,521,255...142,533,462
Ensembl chr 3:142,524,881...142,533,462

G

basigin

increases expression

alpha-Chlorohydrin results in increased expression of BSG protein

NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387

G

bone marrow stromal cell antigen 2

increases expression

alpha-Chlorohydrin results in increased expression of BST2 mRNA

NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979

G

BTG anti-proliferation factor 2

decreases expression

alpha-Chlorohydrin results in decreased expression of BTG2 mRNA

NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628

G

C2CD2-like

increases expression

alpha-Chlorohydrin results in increased expression of C2CD2L mRNA

NCBI chr 8:44,648,074...44,658,856
Ensembl chr 8:44,648,079...44,658,340

G

similar to human chromosome 1 open reading frame 50

increases expression

alpha-Chlorohydrin results in increased expression of C5H1ORF50 protein

NCBI chr 5:132,837,135...132,841,744
Ensembl chr 5:132,836,506...132,841,762

G

similar to human chromosome 11 open reading frame 54

decreases expression

alpha-Chlorohydrin results in decreased expression of C8H11ORF54 protein

NCBI chr 8:12,123,839...12,146,412
Ensembl chr 8:12,123,823...12,146,473

G

calcium voltage-gated channel auxiliary subunit alpha2delta 3

increases expression

alpha-Chlorohydrin results in increased expression of CACNA2D3 protein

NCBI chr16:4,098,439...4,912,498
Ensembl chr16:4,098,445...4,912,351

G

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

increases expression

alpha-Chlorohydrin results in increased expression of CAD protein

NCBI chr 6:25,292,133...25,315,078
Ensembl chr 6:25,292,133...25,319,861

G

cell adhesion molecule 1

increases expression

alpha-Chlorohydrin results in increased expression of CADM1 protein

NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833

G

calbindin 2

increases expression

alpha-Chlorohydrin results in increased expression of CALB2 mRNA

NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438

G

calneuron 1

decreases expression

alpha-Chlorohydrin results in decreased expression of CALN1 mRNA

NCBI chr12:25,811,743...26,303,670
Ensembl chr12:25,819,628...26,303,344

G

calreticulin

decreases expression

alpha-Chlorohydrin analog results in decreased expression of CALR protein; alpha-Chlorohydrin results in decreased expression of CALR protein

NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414

G

calcium/calmodulin-dependent protein kinase II inhibitor 2

decreases expression

alpha-Chlorohydrin results in decreased expression of CAMK2N2 mRNA

NCBI chr11:80,289,702...80,290,829

G

calcium/calmodulin-dependent protein kinase kinase 2

increases expression
multiple interactions

alpha-Chlorohydrin results in increased expression of CAMKK2 protein
4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of CAMKK2 protein]

NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279

G

cyclase associated actin cytoskeleton regulatory protein 1

increases expression

alpha-Chlorohydrin results in increased expression of CAP1 protein

NCBI chr 5:135,142,108...135,168,885
Ensembl chr 5:135,142,112...135,168,769

G

calpain 1

decreases expression

alpha-Chlorohydrin results in decreased expression of CAPN1 mRNA

NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177

G

calpain 2

increases expression

alpha-Chlorohydrin results in increased expression of CAPN2 protein

NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969

G

calpain 5

increases expression

alpha-Chlorohydrin results in increased expression of CAPN5 protein

NCBI chr 1:152,416,252...152,472,923
Ensembl chr 1:152,416,252...152,472,923

G

carbonic anhydrase 12

decreases expression

alpha-Chlorohydrin results in decreased expression of CAR12 protein

NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440

G

carbonic anhydrase 3

decreases expression

alpha-Chlorohydrin analog results in decreased expression of CA3 protein; alpha-Chlorohydrin results in decreased expression of CA3 protein

NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280

G

caspase recruitment domain family, member 19

increases expression

alpha-Chlorohydrin results in increased expression of CARD19 protein

NCBI chr17:15,432,632...15,445,317
Ensembl chr17:15,432,612...15,445,318

G

coactivator-associated arginine methyltransferase 1

increases expression

alpha-Chlorohydrin results in increased expression of CARM1 protein

NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689

G

capping protein regulator and myosin 1 linker 1

increases expression

alpha-Chlorohydrin results in increased expression of CARMIL1 protein

NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326

G

cysteinyl-tRNA synthetase 1

increases expression

alpha-Chlorohydrin results in increased expression of CARS1 protein

NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941

G

caspase 1

decreases expression
increases cleavage
multiple interactions

alpha-Chlorohydrin results in decreased expression of CASP1 mRNA
alpha-Chlorohydrin results in increased cleavage of CASP1 protein
ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP1 protein]
Cyclosporine inhibits the reaction [ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP1 protein]]; ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP1 protein]

PMID:28522335 PMID:33187795 PMID:38373586

NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383

G

caspase 12

multiple interactions

4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP12 protein]; alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP12 protein

NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037

G

caspase 2

multiple interactions
decreases expression

alpha-Chlorohydrin results in increased expression of and results in increased cleavage of and results in increased activity of CASP2 protein; quinoline-val-asp(OMe)-CH2-OPH inhibits the reaction [alpha-Chlorohydrin results in increased activity of CASP2 protein]
alpha-Chlorohydrin results in decreased expression of CASP2 mRNA

NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379

G

caspase 3

decreases expression
multiple interactions
increases activity
increases cleavage
increases expression

alpha-Chlorohydrin results in decreased expression of CASP3 mRNA
alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP3 protein; Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased activity of CASP3 protein]
alpha-Chlorohydrin results in increased cleavage of CASP3 protein
alpha-Chlorohydrin results in increased expression of CASP3 mRNA; alpha-Chlorohydrin results in increased expression of CASP3 protein
4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP3 protein]; Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP3 protein]; Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of CASP3 mRNA]

PMID:27732882 PMID:28070108 PMID:30107153 PMID:33651226 PMID:34461274 More...

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 6

multiple interactions
decreases expression

alpha-Chlorohydrin results in increased expression of and results in increased activity of CASP6 protein; quinoline-val-asp(OMe)-CH2-OPH inhibits the reaction [alpha-Chlorohydrin results in increased activity of CASP6 protein]
alpha-Chlorohydrin results in decreased expression of CASP6 mRNA

NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502

G

caspase 7

decreases expression
multiple interactions

alpha-Chlorohydrin results in decreased expression of CASP7 mRNA
alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP7 protein

NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729

G

caspase 8

multiple interactions
decreases expression
increases activity

alpha-Chlorohydrin results in increased expression of and results in increased cleavage of and results in increased activity of CASP8 protein; quinoline-val-asp(OMe)-CH2-OPH inhibits the reaction [alpha-Chlorohydrin results in increased activity of CASP8 protein]
alpha-Chlorohydrin results in decreased expression of CASP8 mRNA
alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP8 protein

PMID:27732882 PMID:28070108 PMID:34915118

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

G

caspase 9

multiple interactions
decreases expression
increases activity
increases expression
increases cleavage

3-methyladenine inhibits the reaction [Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased activity of CASP9 protein]]; 3-methyladenine inhibits the reaction [Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP9 protein]]; 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP9 protein]; alpha-Chlorohydrin results in increased expression of and results in increased cleavage of and results in increased activity of CASP9 protein; alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP9 protein; Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased activity of CASP9 protein]; Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP9 protein]; Diosgenin promotes the reaction [alpha-Chlorohydrin results in increased expression of CASP9 protein]; quinoline-val-asp(OMe)-CH2-OPH inhibits the reaction [alpha-Chlorohydrin results in increased activity of CASP9 protein]
alpha-Chlorohydrin results in decreased expression of CASP9 mRNA
4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP9 protein]; alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP9 protein; Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP9 protein]; Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of CASP9 mRNA]

PMID:27732882 PMID:28070108 PMID:30107153 PMID:33651226 PMID:35149085

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

catalase

affects expression
decreases expression

alpha-Chlorohydrin affects the expression of CAT protein; alpha-Chlorohydrin analog affects the expression of CAT protein
alpha-Chlorohydrin results in decreased expression of CAT protein

PMID:26597043 PMID:34915118

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

carbonyl reductase 3

increases expression

alpha-Chlorohydrin results in increased expression of CBR3 mRNA

NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875

G

coiled-coil and C2 domain containing 1A

increases expression

alpha-Chlorohydrin results in increased expression of CC2D1A protein

NCBI chr19:24,011,897...24,026,937
Ensembl chr19:24,011,938...24,026,936

G

coiled-coil domain containing 115

increases expression

alpha-Chlorohydrin results in increased expression of CCDC115 protein

NCBI chr 9:36,650,384...36,654,348
Ensembl chr 9:36,649,271...36,653,946

G

coiled-coil domain containing 185

decreases expression

alpha-Chlorohydrin results in decreased expression of CCDC185 mRNA

NCBI chr13:94,434,772...94,436,784
Ensembl chr13:94,434,773...94,436,784

G

coiled-coil domain containing 6

increases expression

alpha-Chlorohydrin results in increased expression of CCDC6 protein

NCBI chr20:18,432,177...18,528,186
Ensembl chr20:18,433,695...18,528,658

G

coiled-coil domain containing 77

increases expression

alpha-Chlorohydrin results in increased expression of CCDC77 mRNA

NCBI chr 4:153,534,184...153,566,059
Ensembl chr 4:153,534,187...153,566,545

G

coiled-coil domain containing 80

increases expression

alpha-Chlorohydrin results in increased expression of CCDC80 mRNA

NCBI chr11:55,685,165...55,718,827
Ensembl chr11:55,685,872...55,719,137

G

coiled-coil domain containing 85C

increases expression

alpha-Chlorohydrin results in increased expression of CCDC85C mRNA

NCBI chr 6:127,113,440...127,184,328
Ensembl chr 6:127,113,442...127,184,371

G

coiled-coil domain containing 89

decreases expression

alpha-Chlorohydrin results in decreased expression of CCDC89 mRNA

NCBI chr 1:144,386,252...144,387,514
Ensembl chr 1:144,386,158...144,389,850

G

coiled-coil domain containing 91

increases expression

alpha-Chlorohydrin results in increased expression of CCDC91 protein

NCBI chr 4:180,402,327...180,574,364
Ensembl chr 4:180,402,376...180,574,364

G

coiled-coil glutamate-rich protein 1

decreases expression

alpha-Chlorohydrin results in decreased expression of CCER1 mRNA

NCBI chr 7:32,485,063...32,521,296
Ensembl chr 7:32,485,041...32,488,394

G

coiled-coil alpha-helical rod protein 1

increases expression

alpha-Chlorohydrin results in increased expression of CCHCR1 protein

NCBI chr20:3,205,675...3,218,437
Ensembl chr20:3,205,676...3,218,308

G

C-C motif chemokine ligand 2

decreases expression
increases expression

alpha-Chlorohydrin results in decreased expression of CCL2 mRNA
alpha-Chlorohydrin results in increased expression of CCL2 protein

PMID:20409345 PMID:26025059

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 5

decreases expression

alpha-Chlorohydrin results in decreased expression of CCL5 mRNA

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

C-C motif chemokine ligand 9

decreases expression

alpha-Chlorohydrin results in decreased expression of CCL6 mRNA

NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369

G

cyclin A2

increases expression

alpha-Chlorohydrin results in increased expression of CCNA2 mRNA

NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577

G

cyclin B1

increases expression

alpha-Chlorohydrin results in increased expression of CCNB1 mRNA

NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172

G

cyclin E1

decreases expression
increases expression

alpha-Chlorohydrin analog results in decreased expression of CCNE1 protein
alpha-Chlorohydrin results in increased expression of CCNE1 mRNA

PMID:26072098 PMID:38301995

NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101

G

cyclin G1

increases expression

alpha-Chlorohydrin results in increased expression of CCNG1 mRNA

NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641

G

chaperonin containing TCP1 subunit 2

increases expression

alpha-Chlorohydrin analog results in increased expression of CCT2 protein

NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944

G

chaperonin containing TCP1 subunit 3

decreases expression

alpha-Chlorohydrin results in decreased expression of CCT3 protein

NCBI chr 2:173,765,701...173,790,353
Ensembl chr 2:173,765,698...173,790,757

G

chaperonin containing TCP1 subunit 4

decreases expression

alpha-Chlorohydrin analog results in decreased expression of CCT4 protein

NCBI chr14:96,991,853...97,004,732
Ensembl chr14:96,991,859...97,005,267

G

chaperonin containing TCP1 subunit 5

increases expression

alpha-Chlorohydrin analog results in increased expression of CCT5 protein

NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930

G

CCZ1 homolog, vacuolar protein trafficking and biogenesis associated

increases expression

alpha-Chlorohydrin results in increased expression of CCZ1B protein

NCBI chr12:10,601,066...10,624,608
Ensembl chr12:10,601,056...10,624,608

G

CD1d1 molecule

increases expression

alpha-Chlorohydrin results in increased expression of CD1D1 protein

NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089

G

CD24 molecule

decreases expression

alpha-Chlorohydrin results in decreased expression of CD24 mRNA

NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662

G

CD27 molecule

increases expression

alpha-Chlorohydrin results in increased expression of CD27 mRNA

NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592

G

CD2-associated protein

increases expression

alpha-Chlorohydrin results in increased expression of CD2AP protein

NCBI chr 9:18,086,744...18,182,744
Ensembl chr 9:18,086,984...18,182,199

G

Cd2 (cytoplasmic tail) binding protein 2

increases expression

alpha-Chlorohydrin results in increased expression of CD2BP2 protein

NCBI chr 1:181,809,399...181,815,269
Ensembl chr 1:181,809,406...181,813,448

G

CD302 molecule

increases expression

alpha-Chlorohydrin results in increased expression of CD302 mRNA

NCBI chr 3:44,722,324...44,756,045
Ensembl chr 3:44,722,325...44,756,045

G

CD34 molecule

increases expression

alpha-Chlorohydrin results in increased expression of CD34 mRNA

NCBI chr13:106,480,313...106,500,844
Ensembl chr13:106,480,043...106,499,832

G

CD36 molecule

increases expression

alpha-Chlorohydrin results in increased expression of CD36 mRNA

NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903

G

CD38 molecule

decreases expression

alpha-Chlorohydrin results in decreased expression of CD38 mRNA

NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986

G

Cd4 molecule

increases expression

alpha-Chlorohydrin results in increased expression of CD4 protein

NCBI chr 4:157,668,878...157,695,366

G

Cd48 molecule

decreases expression

alpha-Chlorohydrin results in decreased expression of CD48 mRNA

NCBI chr13:84,184,884...84,209,144
Ensembl chr13:84,185,532...84,209,142

G

Cd53 molecule

increases expression

alpha-Chlorohydrin results in increased expression of CD53 mRNA

NCBI chr 2:194,352,139...194,399,668
Ensembl chr 2:194,352,139...194,399,657

G

Cd68 molecule

increases expression

alpha-Chlorohydrin results in increased expression of CD68 mRNA

NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697

G

Cd69 molecule

decreases expression

alpha-Chlorohydrin results in decreased expression of CD69 mRNA

NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542

G

Cd70 molecule

decreases expression

alpha-Chlorohydrin results in decreased expression of CD70 mRNA

NCBI chr 9:2,006,563...2,009,715
Ensembl chr 9:2,006,563...2,009,715

G

CD9 molecule

decreases expression
increases expression

alpha-Chlorohydrin results in decreased expression of CD9 mRNA
alpha-Chlorohydrin results in increased expression of CD9 protein

PMID:28522335 PMID:34915118

NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222

G

cell division cycle 123

increases expression

alpha-Chlorohydrin results in increased expression of CDC123 protein

NCBI chr17:72,459,270...72,503,316
Ensembl chr17:72,459,282...72,503,316

G

cell division cycle 16

increases expression

alpha-Chlorohydrin results in increased expression of CDC16 protein

NCBI chr16:75,773,026...75,796,586
Ensembl chr16:75,773,028...75,796,550

G

cell division cycle 25B

decreases expression

alpha-Chlorohydrin results in decreased expression of CDC25B mRNA

NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272

G

cell division cycle 5-like

increases expression

alpha-Chlorohydrin results in increased expression of CDC5L protein

NCBI chr 9:15,564,949...15,603,453
Ensembl chr 9:15,564,767...15,603,450

G

cell division cycle 6

increases expression

alpha-Chlorohydrin results in increased expression of CDC6 mRNA

NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011

G

cell division cycle associated 3

decreases expression

alpha-Chlorohydrin analog results in decreased expression of CDCA3 protein; alpha-Chlorohydrin results in decreased expression of CDCA3 mRNA

PMID:26597043 PMID:28522335

NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799

G

cell division cycle associated 8

increases expression

alpha-Chlorohydrin results in increased expression of CDCA8 mRNA

NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629

G

cadherin 1

decreases expression
affects methylation

alpha-Chlorohydrin results in decreased expression of CDH1 mRNA
alpha-Chlorohydrin affects the methylation of CDH1 promoter

PMID:27884059 PMID:28522335

NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775

G

cadherin 2

decreases expression

alpha-Chlorohydrin results in decreased expression of CDH2 mRNA

NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167

G

cadherin 5

increases expression

alpha-Chlorohydrin results in increased expression of CDH5 mRNA

NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368

G

cadherin-related family member 5

increases expression

alpha-Chlorohydrin results in increased expression of CDHR5 mRNA

NCBI chr 1:196,373,110...196,381,609
Ensembl chr 1:196,373,112...196,381,543

G

CDK5 regulatory subunit associated protein 1

increases expression

alpha-Chlorohydrin results in increased expression of CDK5RAP1 protein

NCBI chr 3:142,838,081...142,872,669
Ensembl chr 3:142,708,028...142,872,677

G

cyclin-dependent kinase-like 5

increases expression

alpha-Chlorohydrin results in increased expression of CDKL5 mRNA

NCBI chr X:33,757,605...33,988,075
Ensembl chr X:33,821,257...33,986,582

G

cyclin-dependent kinase inhibitor 2A

increases expression

alpha-Chlorohydrin analog results in increased expression of CDKN2A protein; alpha-Chlorohydrin results in increased expression of CDKN2A protein

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

G

cysteine dioxygenase type 1

decreases expression

alpha-Chlorohydrin analog results in decreased expression of CDO1 protein; alpha-Chlorohydrin results in decreased expression of CDO1 protein

NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296

G

CEA cell adhesion molecule 1

increases expression

alpha-Chlorohydrin results in increased expression of CEACAM1 protein

NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992

G

CEA cell adhesion molecule 20

decreases expression

alpha-Chlorohydrin results in decreased expression of CEACAM20 mRNA

NCBI chr 1:79,622,077...79,643,782
Ensembl chr 1:79,622,077...79,643,782

G

cell migration inducing hyaluronidase 1

increases expression

alpha-Chlorohydrin results in increased expression of CEMIP mRNA

NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415

G

centrosomal protein 152

increases expression

alpha-Chlorohydrin results in increased expression of CEP152 mRNA

NCBI chr 3:112,803,185...112,878,298
Ensembl chr 3:112,810,425...112,878,458
Ensembl chr 3:112,810,425...112,878,458

G

centrosomal protein 55

increases expression

alpha-Chlorohydrin results in increased expression of CEP55 mRNA

NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394

G

centrosomal protein 68

increases expression

alpha-Chlorohydrin results in increased expression of CEP68 protein

NCBI chr14:94,447,973...94,470,533
Ensembl chr14:94,449,055...94,470,517

G

carboxylesterase 1D

increases expression

alpha-Chlorohydrin analog results in increased expression of CES1 protein; alpha-Chlorohydrin results in increased expression of CES1 protein

NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035

G

CASP8 and FADD-like apoptosis regulator

increases expression

alpha-Chlorohydrin results in increased expression of CFLAR protein

NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034

G

complement factor properdin

decreases expression

alpha-Chlorohydrin results in decreased expression of CFP mRNA

NCBI chr X:1,162,014...1,167,576
Ensembl chr X:1,161,979...1,167,573

G

ChaC glutathione-specific gamma-glutamylcyclotransferase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of CHAC1 mRNA

NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526

G

coiled-coil-helix-coiled-coil-helix domain containing 1

decreases expression

alpha-Chlorohydrin results in decreased expression of CHCHD1 mRNA

NCBI chr15:3,592,719...3,593,901
Ensembl chr15:3,592,727...3,593,901

G

cholinergic receptor, muscarinic 3

decreases expression

alpha-Chlorohydrin results in decreased expression of CHRM3 mRNA

NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278

G

CIMAP1 family member D

decreases expression

alpha-Chlorohydrin results in decreased expression of CIMAP1D mRNA

NCBI chr 7:10,049,472...10,065,626
Ensembl chr 7:10,059,589...10,065,125

G

cytoskeleton-associated protein 4

increases expression

alpha-Chlorohydrin results in increased expression of CKAP4 protein

NCBI chr 7:19,230,814...19,238,914
Ensembl chr 7:19,230,203...19,238,914

G

chloride voltage-gated channel 7

decreases expression
multiple interactions

alpha-Chlorohydrin results in decreased expression of CLCN7 mRNA
ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of CLCN7 mRNA]

NCBI chr10:14,151,758...14,177,130
Ensembl chr10:14,151,758...14,177,130

G

claudin 1

increases expression

alpha-Chlorohydrin results in increased expression of CLDN1 mRNA; alpha-Chlorohydrin results in increased expression of CLDN1 protein

PMID:28522335 PMID:34915118

NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724

G

claudin 17

decreases expression

alpha-Chlorohydrin results in decreased expression of CLDN17 mRNA

NCBI chr11:27,827,454...27,828,630
Ensembl chr11:27,827,454...27,828,630

G

claudin 8

decreases expression

alpha-Chlorohydrin results in decreased expression of CLDN8 mRNA

NCBI chr11:27,875,857...27,878,106
Ensembl chr11:27,875,692...27,878,513

G

C-type lectin domain family 2, member D

decreases expression

alpha-Chlorohydrin results in decreased expression of CLEC2D mRNA

NCBI chr 4:162,216,052...162,239,530
Ensembl chr 4:162,216,572...162,239,527

G

chloride intracellular channel 1

decreases expression

alpha-Chlorohydrin results in decreased expression of CLIC1 mRNA

NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712

G

chloride intracellular channel 2

increases expression

alpha-Chlorohydrin results in increased expression of CLIC2 mRNA

NCBI chr20:149,337...164,375
Ensembl chr20:148,907...164,355

G

CAP-GLY domain containing linker protein 1

increases expression

alpha-Chlorohydrin results in increased expression of CLIP1 protein

NCBI chr12:32,910,932...33,017,891
Ensembl chr12:32,910,977...33,017,884

G

calmin

increases expression

alpha-Chlorohydrin results in increased expression of CLMN mRNA

NCBI chr 6:123,707,710...123,807,283
Ensembl chr 6:123,713,507...123,807,272

G

CLN3 lysosomal/endosomal transmembrane protein, battenin

increases expression

alpha-Chlorohydrin results in increased expression of CLN3 protein

NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434

G

ClpB family mitochondrial disaggregase

increases expression

alpha-Chlorohydrin results in increased expression of CLPB protein

NCBI chr 1:156,028,740...156,158,183
Ensembl chr 1:156,028,930...156,168,788

G

caseinolytic mitochondrial matrix peptidase chaperone subunit X

decreases expression
increases expression

alpha-Chlorohydrin analog results in decreased expression of CLPX protein
alpha-Chlorohydrin results in increased expression of CLPX protein

PMID:26597043 PMID:34915118

NCBI chr 8:65,805,460...65,845,643
Ensembl chr 8:65,805,511...65,845,082

G

clarin 3

increases expression
decreases expression

alpha-Chlorohydrin results in increased expression of CLRN3 mRNA
alpha-Chlorohydrin results in decreased expression of CLRN3 protein

PMID:28522335 PMID:34915118

NCBI chr 1:190,319,025...190,334,648
Ensembl chr 1:190,319,026...190,334,648

G

clusterin

multiple interactions

[alpha-Chlorohydrin co-treated with glycidol] results in increased expression of CLU mRNA

NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315

G

citramalyl-CoA lyase

increases expression

alpha-Chlorohydrin results in increased expression of CLYBL mRNA

NCBI chr15:99,283,644...99,505,697
Ensembl chr15:99,283,650...99,505,695

G

cytidine monophosphate N-acetylneuraminic acid synthetase

increases expression

alpha-Chlorohydrin results in increased expression of CMAS protein

NCBI chr 4:175,718,808...175,737,128
Ensembl chr 4:175,718,808...175,737,125

G

carboxymethylenebutenolidase homolog

decreases expression

alpha-Chlorohydrin analog results in decreased expression of CMBL protein

NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009

G

c-Maf-inducing protein

increases expression

alpha-Chlorohydrin results in increased expression of CMIP mRNA

NCBI chr19:45,304,597...45,510,653
Ensembl chr19:45,304,031...45,508,709

G

CKLF-like MARVEL transmembrane domain containing 8

decreases expression

alpha-Chlorohydrin results in decreased expression of CMTM8 mRNA

NCBI chr 8:114,481,730...114,547,107
Ensembl chr 8:114,481,982...114,547,083

G

cornichon family member 4

increases expression

alpha-Chlorohydrin results in increased expression of CNIH4 protein

NCBI chr13:92,910,315...92,926,428
Ensembl chr13:92,910,315...92,927,853

G

connector enhancer of kinase suppressor of Ras 1

decreases expression

alpha-Chlorohydrin results in decreased expression of CNKSR1 mRNA

NCBI chr 5:146,447,495...146,458,332
Ensembl chr 5:146,447,497...146,458,212

G

cyclin and CBS domain divalent metal cation transport mediator 2

decreases expression

alpha-Chlorohydrin results in decreased expression of CNNM2 protein

NCBI chr 1:245,643,682...245,769,542
Ensembl chr 1:245,643,768...245,763,286

G

cyclin and CBS domain divalent metal cation transport mediator 4

increases expression

alpha-Chlorohydrin results in increased expression of CNNM4 protein

NCBI chr 9:38,711,726...38,750,942
Ensembl chr 9:38,711,710...38,750,942

G

CCR4-NOT transcription complex, subunit 10

increases expression

alpha-Chlorohydrin results in increased expression of CNOT10 protein

NCBI chr 8:114,280,486...114,330,110
Ensembl chr 8:114,280,490...114,330,107

G

2',3'-cyclic nucleotide 3' phosphodiesterase

increases expression

alpha-Chlorohydrin results in increased expression of CNP protein

NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720

G

cordon-bleu WH2 repeat protein

increases expression

alpha-Chlorohydrin results in increased expression of COBL mRNA

NCBI chr14:86,828,137...87,060,682
Ensembl chr14:86,828,139...87,060,800

G

component of oligomeric golgi complex 4

increases expression

alpha-Chlorohydrin results in increased expression of COG4 protein

NCBI chr19:38,820,478...38,854,803
Ensembl chr19:38,820,501...38,854,796

G

collagen type XXVII alpha 1 chain

multiple interactions

[alpha-Chlorohydrin co-treated with glycidol] results in decreased expression of COL27A1 mRNA

NCBI chr 5:76,647,302...76,765,989
Ensembl chr 5:76,647,429...76,765,174

G

collagen type IV alpha 1 chain

increases expression

alpha-Chlorohydrin results in increased expression of COL4A1 protein

NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412

G

collagen type V alpha 2 chain

decreases expression

alpha-Chlorohydrin results in decreased expression of COL5A2 mRNA

NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154

G

collagen type VI alpha 1 chain

increases expression

alpha-Chlorohydrin results in increased expression of COL6A1 mRNA

NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597

G

collagen beta(1-O)galactosyltransferase 1

increases expression

alpha-Chlorohydrin results in increased expression of COLGALT1 protein

NCBI chr16:18,319,796...18,332,106
Ensembl chr16:18,319,795...18,332,106

G

catechol-O-methyltransferase

decreases expression

alpha-Chlorohydrin analog results in decreased expression of COMT protein; alpha-Chlorohydrin results in decreased expression of COMT protein

NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642

G

catechol-O-methyltransferase domain containing 1

increases expression

alpha-Chlorohydrin results in increased expression of COMTD1 protein

NCBI chr15:2,459,783...2,462,895
Ensembl chr15:2,459,783...2,462,895

G

COPI coat complex subunit zeta 2

increases expression

alpha-Chlorohydrin results in increased expression of COPZ2 mRNA

NCBI chr10:81,832,441...81,845,514
Ensembl chr10:81,832,418...81,845,514

G

coenzyme Q10A

decreases expression

alpha-Chlorohydrin results in decreased expression of COQ10A protein

NCBI chr 7:792,089...798,392
Ensembl chr 7:792,089...800,161

G

coenzyme Q10B

decreases expression

alpha-Chlorohydrin results in decreased expression of COQ10B protein

NCBI chr 9:56,553,751...56,573,671
Ensembl chr 9:56,553,758...56,573,663

G

coenzyme Q3 methyltransferase

increases expression

alpha-Chlorohydrin results in increased expression of COQ3 protein

NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607

G

coenzyme Q8B

increases expression

alpha-Chlorohydrin results in increased expression of COQ8B protein

NCBI chr 1:82,525,578...82,549,182
Ensembl chr 1:82,526,568...82,549,180

G

coronin 1A

increases expression

alpha-Chlorohydrin results in increased expression of CORO1A protein

NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534

G

cytochrome c oxidase assembly factor COX14

decreases expression

alpha-Chlorohydrin results in decreased expression of COX14 mRNA

NCBI chr 7:130,852,226...130,854,316

G

cytochrome c oxidase copper chaperone COX17

affects expression
decreases expression
multiple interactions
increases expression

alpha-Chlorohydrin affects the expression of COX17 mRNA
alpha-Chlorohydrin results in decreased expression of COX17 protein
Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of COX17 mRNA]; Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of COX17 protein]
alpha-Chlorohydrin results in increased expression of COX17 mRNA; alpha-Chlorohydrin results in increased expression of COX17 protein

PMID:27732882 PMID:30107153

NCBI chr11:62,400,733...62,406,507

G

copine 3

increases expression

alpha-Chlorohydrin results in increased expression of CPNE3 mRNA

NCBI chr 5:33,014,658...33,063,934
Ensembl chr 5:33,016,307...33,063,934

G

coproporphyrinogen oxidase

increases expression

alpha-Chlorohydrin results in increased expression of CPOX protein

NCBI chr11:41,936,585...41,946,568
Ensembl chr11:41,936,591...41,946,746

G

carboxypeptidase Q

decreases expression

alpha-Chlorohydrin results in decreased expression of CPQ protein

NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546

G

carbamoyl-phosphate synthase 1

affects expression
decreases expression

alpha-Chlorohydrin analog affects the expression of CPS1 protein
alpha-Chlorohydrin results in decreased expression of CPS1 protein

NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033

G

cleavage and polyadenylation specific factor 2

increases expression

alpha-Chlorohydrin results in increased expression of CPSF2 protein

NCBI chr 6:121,123,941...121,152,756
Ensembl chr 6:121,120,569...121,151,921

G

cleavage and polyadenylation specific factor 6

increases expression

alpha-Chlorohydrin results in increased expression of CPSF6 protein

NCBI chr 7:52,956,589...53,001,783
Ensembl chr 7:52,956,589...52,988,122

G

carnitine palmitoyltransferase 1A

increases expression

alpha-Chlorohydrin results in increased expression of CPT1A mRNA

NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055

G

carnitine palmitoyltransferase 2

affects expression

alpha-Chlorohydrin analog affects the expression of CPT2 protein

NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095

G

CASP2 and RIPK1 domain containing adaptor with death domain

decreases expression

alpha-Chlorohydrin results in decreased expression of CRADD mRNA

NCBI chr 7:29,940,240...29,952,907
Ensembl chr 7:29,798,586...29,952,907

G

cAMP responsive element binding protein 1

decreases phosphorylation

alpha-Chlorohydrin results in decreased phosphorylation of CREB1 protein

NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816

G

cellular repressor of E1A-stimulated genes 1

increases expression

alpha-Chlorohydrin results in increased expression of CREG1 protein

NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308

G

cartilage associated protein

increases expression

alpha-Chlorohydrin results in increased expression of CRTAP mRNA

NCBI chr 8:114,047,929...114,067,636
Ensembl chr 8:114,047,933...114,067,631

G

cryptochrome circadian regulator 1

decreases expression

alpha-Chlorohydrin results in decreased expression of CRY1 mRNA

NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091

G

crystallin, alpha B

multiple interactions

[alpha-Chlorohydrin co-treated with glycidol] results in increased expression of CRYAB mRNA

NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157

G

crystallin, lambda 1

increases expression

alpha-Chlorohydrin results in increased expression of CRYL1 mRNA

NCBI chr15:31,427,011...31,545,997
Ensembl chr15:31,427,054...31,545,997

G

crystallin, mu

decreases expression

alpha-Chlorohydrin results in decreased expression of CRYM mRNA

NCBI chr 1:174,560,423...174,575,660
Ensembl chr 1:174,560,416...174,575,633

G

cysteine sulfinic acid decarboxylase

increases expression

alpha-Chlorohydrin analog results in increased expression of CSAD protein; alpha-Chlorohydrin results in increased expression of CSAD protein

NCBI chr 7:133,308,571...133,337,914
Ensembl chr 7:133,308,574...133,337,615

G

C-terminal Src kinase

increases expression

alpha-Chlorohydrin results in increased expression of CSK protein

NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292

G

cysteine and glycine-rich protein 1

increases expression

alpha-Chlorohydrin results in increased expression of CSRP1 mRNA; alpha-Chlorohydrin results in increased expression of CSRP1 protein

PMID:28522335 PMID:34915118

NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384

G

cystatin C

decreases expression
multiple interactions

alpha-Chlorohydrin results in decreased expression of CST3 mRNA
4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and affects the localization of CST3 protein]; alpha-Chlorohydrin results in increased expression of and affects the localization of CST3 protein

PMID:28522335 PMID:33651226

NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822

G

cystatin E/M

decreases expression

alpha-Chlorohydrin results in decreased expression of CST6 protein

NCBI chr 1:202,655,322...202,657,030
Ensembl chr 1:202,655,322...202,657,030

G

cystatin B

decreases expression

alpha-Chlorohydrin results in decreased expression of CSTB mRNA

NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526

G

cystathionine gamma-lyase

affects expression
increases expression

alpha-Chlorohydrin affects the expression of CTH protein
alpha-Chlorohydrin analog results in increased expression of CTH protein

NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234

G

cystinosin, lysosomal cystine transporter

increases expression

alpha-Chlorohydrin results in increased expression of CTNS mRNA

NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120

G

CTP synthase 1

increases expression

alpha-Chlorohydrin results in increased expression of CTPS1 protein

NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180

G

cathepsin B

decreases expression
multiple interactions

alpha-Chlorohydrin results in decreased expression of CTSB mRNA
ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of CTSB mRNA]

PMID:32702505 PMID:34812491

NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500

G

cathepsin C

increases expression

alpha-Chlorohydrin results in increased expression of CTSC mRNA

NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387

G

cathepsin D

multiple interactions
decreases expression

ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of CTSD mRNA]

NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488

G

cathepsin S

decreases expression

alpha-Chlorohydrin results in decreased expression of CTSS mRNA

NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483

G

cathepsin Z

decreases expression

alpha-Chlorohydrin results in decreased expression of CTSZ mRNA

NCBI chr 3:163,224,875...163,235,645
Ensembl chr 3:163,224,875...163,235,645

G

cullin 2

decreases expression

alpha-Chlorohydrin results in decreased expression of CUL2 mRNA

NCBI chr17:54,169,093...54,210,197
Ensembl chr17:54,169,086...54,209,968

G

CWC22 spliceosome associated protein

increases expression

alpha-Chlorohydrin results in increased expression of CWC22 protein

NCBI chr 3:62,815,230...62,864,269
Ensembl chr 3:62,802,045...62,864,228

G

C-X-C motif chemokine ligand 13

increases expression
decreases expression

alpha-Chlorohydrin results in increased expression of CXCL13 mRNA
alpha-Chlorohydrin results in decreased expression of CXCL13 mRNA

PMID:20409345 PMID:28522335

NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933

G

C-X-C motif chemokine ligand 2

increases expression
multiple interactions

alpha-Chlorohydrin analog results in increased expression of CXCL2 mRNA
MLKL protein affects the reaction [alpha-Chlorohydrin analog results in increased expression of CXCL2 mRNA]; RIPK3 protein affects the reaction [alpha-Chlorohydrin analog results in increased expression of CXCL2 mRNA]

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

G

C-X-C motif chemokine ligand 3

increases expression
multiple interactions

alpha-Chlorohydrin analog results in increased expression of CXCL1 mRNA
MLKL protein affects the reaction [alpha-Chlorohydrin analog results in increased expression of CXCL1 mRNA]; RIPK3 protein affects the reaction [alpha-Chlorohydrin analog results in increased expression of CXCL1 mRNA]

NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511

G

C-X-C motif chemokine ligand 9

decreases expression

alpha-Chlorohydrin results in decreased expression of CXCL9 mRNA

NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435

G

cytochrome b5 reductase 1

increases expression

alpha-Chlorohydrin results in increased expression of CYB5R1 protein

NCBI chr13:45,849,017...45,855,458
Ensembl chr13:45,849,091...45,855,458

G

cytochrome b5 reductase 3

increases expression

alpha-Chlorohydrin results in increased expression of CYB5R3 mRNA

NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298

G

cytochrome b5 reductase 4

increases expression

alpha-Chlorohydrin results in increased expression of CYB5R4 protein

NCBI chr 8:87,975,596...88,048,356
Ensembl chr 8:87,981,116...88,045,832

G

cytochrome b-245 alpha chain

affects expression

alpha-Chlorohydrin affects the expression of CYBA mRNA

NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721

G

cytochrome c, somatic

increases expression

alpha-Chlorohydrin results in increased expression of CYCS mRNA; alpha-Chlorohydrin results in increased expression of CYCS protein

NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054

G

cytoplasmic FMR1 interacting protein 2

decreases expression

alpha-Chlorohydrin results in decreased expression of CYFIP2 mRNA

NCBI chr10:30,621,318...30,741,113
Ensembl chr10:30,621,318...30,741,113

G

cytoglobin

increases expression

alpha-Chlorohydrin results in increased expression of CYGB mRNA; alpha-Chlorohydrin results in increased expression of CYGB protein

PMID:28522335 PMID:34915118

NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442

G

cytochrome P450, family 11, subfamily a, polypeptide 1

increases expression

alpha-Chlorohydrin results in increased expression of CYP11A1 mRNA

NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338

G

cytochrome P450, family 17, subfamily a, polypeptide 1

increases expression

alpha-Chlorohydrin results in increased expression of CYP17A1 mRNA

NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573

G

cytochrome P450, family 24, subfamily a, polypeptide 1

decreases expression

alpha-Chlorohydrin results in decreased expression of CYP24A1 mRNA

NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383

G

cytochrome P450, family 2, subfamily b, polypeptide 3

decreases expression

alpha-Chlorohydrin results in decreased expression of CYP2B6 mRNA

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, family 2, subfamily e, polypeptide 1

decreases expression

alpha-Chlorohydrin results in decreased expression of CYP2E1 protein

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 2, subfamily j, polypeptide 4

increases expression

alpha-Chlorohydrin results in increased expression of CYP2J4 mRNA

NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794

G

cytochrome P450, family 2, subfamily t, polypeptide 1

decreases expression

alpha-Chlorohydrin results in decreased expression of CYP2T1 protein

NCBI chr 1:82,446,321...82,451,564
Ensembl chr 1:82,446,921...82,451,563

G

cytochrome P450, family 4, subfamily b, polypeptide 1

multiple interactions

[alpha-Chlorohydrin co-treated with glycidol] results in decreased expression of CYP4B1 mRNA

NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348

G

cytochrome P450, family 4, subfamily v, polypeptide 3

decreases expression

alpha-Chlorohydrin results in decreased expression of CYP4V3 mRNA

NCBI chr16:46,917,929...46,958,735
Ensembl chr16:46,918,401...46,943,395

G

cytochrome P450 family 7 subfamily B member 1

increases expression

alpha-Chlorohydrin results in increased expression of CYP7B1 protein

NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698

G

cystin 1

increases expression

alpha-Chlorohydrin results in increased expression of CYS1 mRNA

NCBI chr 6:41,300,836...41,318,071
Ensembl chr 6:41,300,836...41,318,071

G

CXXC motif containing zinc binding protein

decreases expression

alpha-Chlorohydrin results in decreased expression of CZIB protein

NCBI chr 5:122,648,333...122,657,767
Ensembl chr 5:122,648,411...122,656,910

G

D-amino-acid oxidase

decreases expression

alpha-Chlorohydrin results in decreased expression of DAO protein

NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741

G

death-associated protein

increases expression

alpha-Chlorohydrin results in increased expression of DAP mRNA

NCBI chr 2:82,199,206...82,251,771
Ensembl chr 2:82,199,280...82,251,752

G

death associated protein 3

increases expression

alpha-Chlorohydrin results in increased expression of DAP3 protein

NCBI chr 2:174,319,341...174,347,489
Ensembl chr 2:174,318,983...174,346,461

G

death associated protein kinase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of DAPK1 mRNA

NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991

G

aspartyl-tRNA synthetase 1

increases expression

alpha-Chlorohydrin results in increased expression of DARS1 protein

NCBI chr13:39,857,936...39,913,055
Ensembl chr13:39,857,936...39,913,116

G

dihydrolipoamide branched chain transacylase E2

decreases expression

alpha-Chlorohydrin results in decreased expression of DBT protein

NCBI chr 2:204,481,744...204,510,612
Ensembl chr 2:204,481,737...204,510,609

G

DDB1 and CUL4 associated factor 11

increases expression

alpha-Chlorohydrin results in increased expression of DCAF11 protein

NCBI chr15:29,046,744...29,057,450
Ensembl chr15:29,046,826...29,057,669

G

deoxycytidine kinase

decreases expression

alpha-Chlorohydrin analog results in decreased expression of DCK protein; alpha-Chlorohydrin results in decreased expression of DCK protein

NCBI chr14:19,305,218...19,326,247
Ensembl chr14:19,305,218...19,326,247

G

decorin

affects expression

alpha-Chlorohydrin affects the expression of DCN mRNA

NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270

G

dynactin subunit 2

decreases expression

alpha-Chlorohydrin analog results in decreased expression of DCTN2 protein; alpha-Chlorohydrin results in decreased expression of DCTN2 protein

NCBI chr 7:63,092,061...63,107,560
Ensembl chr 7:63,092,057...63,108,543

G

dicarbonyl and L-xylulose reductase

decreases expression

alpha-Chlorohydrin results in decreased expression of DCXR protein

NCBI chr10:106,006,404...106,008,293

G

dimethylarginine dimethylaminohydrolase 1

increases expression

alpha-Chlorohydrin results in increased expression of DDAH1 mRNA

NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339

G

DNA-damage inducible transcript 3

increases phosphorylation
multiple interactions

alpha-Chlorohydrin results in increased phosphorylation of DDIT3 protein
4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased phosphorylation of DDIT3 protein]

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit

increases expression

alpha-Chlorohydrin analog results in increased expression of DDOST protein; alpha-Chlorohydrin results in increased expression of DDOST protein

NCBI chr 5:150,522,297...150,529,413
Ensembl chr 5:150,522,242...150,529,413

G

D-dopachrome tautomerase

increases expression

alpha-Chlorohydrin results in increased expression of DDT mRNA

NCBI chr20:12,884,216...12,886,687
Ensembl chr20:12,884,243...12,888,482

G

DEAD-box helicase 18

increases expression

alpha-Chlorohydrin results in increased expression of DDX18 protein

NCBI chr13:32,729,697...32,743,161
Ensembl chr13:32,729,700...32,743,161

G

DEAD-box helicase 19A

increases expression

alpha-Chlorohydrin results in increased expression of DDX19A mRNA

NCBI chr19:38,942,497...38,962,853
Ensembl chr19:38,942,496...38,962,854

G

DEAD-box helicase 23

increases expression

alpha-Chlorohydrin results in increased expression of DDX23 protein

NCBI chr 7:129,797,620...129,814,909
Ensembl chr 7:129,797,614...129,814,949

G

DExD-box helicase 39B

increases expression

alpha-Chlorohydrin analog results in increased expression of BAT1 protein; alpha-Chlorohydrin results in increased expression of BAT1 protein

NCBI chr20:3,547,702...3,585,064
Ensembl chr20:3,572,056...3,584,996

G

DEAD-box helicase 4

decreases expression

alpha-Chlorohydrin results in decreased expression of DDX4 protein

NCBI chr 2:44,227,946...44,282,867
Ensembl chr 2:44,227,946...44,282,723

G

DEAD-box helicase 41

increases expression

alpha-Chlorohydrin results in increased expression of DDX41 protein

NCBI chr17:9,102,926...9,108,415
Ensembl chr17:9,103,010...9,108,415

G

DEAD-box helicase 47

increases expression

alpha-Chlorohydrin results in increased expression of DDX47 protein

NCBI chr 4:167,845,652...167,858,115
Ensembl chr 4:167,845,640...167,859,115

G

DExD-box helicase 50

increases expression

alpha-Chlorohydrin results in increased expression of DDX50 protein

NCBI chr20:30,561,623...30,591,324
Ensembl chr20:30,560,544...30,591,152

G

DExD-box helicase 52

increases expression

alpha-Chlorohydrin results in increased expression of DDX52 protein

NCBI chr10:68,824,594...68,847,400
Ensembl chr10:68,824,645...68,848,266

G

DEAD-box helicase 59

increases expression

alpha-Chlorohydrin results in increased expression of DDX59 protein

NCBI chr13:47,876,258...47,901,214
Ensembl chr13:47,876,261...47,901,214

G

2,4-dienoyl-CoA reductase 2

decreases expression

alpha-Chlorohydrin results in decreased expression of DECR2 protein

NCBI chr10:15,104,907...15,113,281
Ensembl chr10:15,002,926...15,118,479

G

defensin beta 1

decreases expression

alpha-Chlorohydrin results in decreased expression of DEFB1 mRNA

NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604

G

DEPP autophagy regulator 1

multiple interactions

[alpha-Chlorohydrin co-treated with glycidol] results in increased expression of DEPP1 mRNA

NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542

G

desmin

increases expression

alpha-Chlorohydrin results in increased expression of DES protein

NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699

G

dehydrogenase/reductase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of DHRS1 protein

NCBI chr15:29,236,522...29,243,807
Ensembl chr15:29,236,522...29,243,838

G

dehydrogenase/reductase 7B

increases expression

alpha-Chlorohydrin results in increased expression of DHRS7B protein

NCBI chr10:45,504,344...45,537,094
Ensembl chr10:45,504,426...45,537,076

G

dehydrogenase E1 and transketolase domain containing 1

decreases expression

alpha-Chlorohydrin results in decreased expression of DHTKD1 protein

NCBI chr17:72,355,201...72,406,725
Ensembl chr17:72,355,201...72,406,723

G

DExH-box helicase 30

increases expression

alpha-Chlorohydrin results in increased expression of DHX30 protein

NCBI chr 8:110,064,751...110,096,954
Ensembl chr 8:110,064,752...110,097,381

G

diaphanous-related formin 1

increases expression

alpha-Chlorohydrin results in increased expression of DIAPH1 protein

NCBI chr18:29,669,659...29,769,070
Ensembl chr18:29,669,659...29,769,172

G

iodothyronine deiodinase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of DIO1 protein

NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970

G

divergent protein kinase domain 1A

increases expression

alpha-Chlorohydrin results in increased expression of DIPK1A mRNA

NCBI chr14:1,772,412...1,843,508
Ensembl chr14:1,772,422...1,843,743

G

dyskerin pseudouridine synthase 1

increases expression

alpha-Chlorohydrin results in increased expression of DKC1 protein

G

delta like canonical Notch ligand 4

decreases expression

alpha-Chlorohydrin results in decreased expression of DLL4 mRNA

NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931

G

distal membrane arm assembly component 2

increases expression

alpha-Chlorohydrin results in increased expression of DMAC2 protein

NCBI chr 1:81,128,760...81,134,810
Ensembl chr 1:81,128,857...81,134,812

G

dimethylglycine dehydrogenase

increases expression

alpha-Chlorohydrin analog results in increased expression of DMGDH protein

NCBI chr 2:24,912,600...24,987,533
Ensembl chr 2:24,912,578...24,987,528

G

DnaJ heat shock protein family (Hsp40) member B1

increases expression

alpha-Chlorohydrin results in increased expression of DNAJB1 protein

NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458

G

DnaJ heat shock protein family (Hsp40) member B2

increases expression

alpha-Chlorohydrin results in increased expression of DNAJB2 protein

NCBI chr 9:76,731,060...76,739,278
Ensembl chr 9:76,731,065...76,739,277

G

DnaJ heat shock protein family (Hsp40) member B4

increases expression

alpha-Chlorohydrin results in increased expression of DNAJB4 protein

NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089

G

DnaJ heat shock protein family (Hsp40) member B6

increases expression

alpha-Chlorohydrin results in increased expression of DNAJB6 protein

NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659

G

DnaJ heat shock protein family (Hsp40) member C3

decreases expression

alpha-Chlorohydrin analog results in decreased expression of DNAJC3 protein; alpha-Chlorohydrin results in decreased expression of DNAJC3 protein

NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181

G

DnaJ heat shock protein family (Hsp40) member C5 beta

decreases expression

alpha-Chlorohydrin results in decreased expression of DNAJC5B mRNA

NCBI chr 2:101,973,726...102,066,275
Ensembl chr 2:101,973,793...102,066,275

G

DnaJ heat shock protein family (Hsp40) member C6

increases expression

alpha-Chlorohydrin results in increased expression of DNAJC6 mRNA

NCBI chr 5:116,120,069...116,283,448
Ensembl chr 5:116,119,676...116,283,448

G

DnaJ heat shock protein family (Hsp40) member C8

increases expression

alpha-Chlorohydrin results in increased expression of DNAJC8 protein

NCBI chr 5:144,745,055...144,763,106
Ensembl chr 5:144,745,036...144,763,108

G

deoxyribonuclease 1

multiple interactions

[alpha-Chlorohydrin co-treated with glycidol] results in decreased expression of DNASE1 mRNA

NCBI chr10:11,498,930...11,505,151
Ensembl chr10:11,498,931...11,501,869

G

deoxyribonuclease 1L3

increases expression

alpha-Chlorohydrin results in increased expression of DNASE1L3 mRNA

PMID:20409345 PMID:28522335

NCBI chr15:16,922,335...16,948,322
Ensembl chr15:16,922,335...16,948,317

G

deoxyribonuclease 2, lysosomal

decreases expression

alpha-Chlorohydrin results in decreased expression of DNASE2 mRNA; alpha-Chlorohydrin results in decreased expression of DNASE2 protein

PMID:28522335 PMID:34915118

NCBI chr19:23,244,656...23,247,376
Ensembl chr19:23,244,664...23,247,376

G

dynamin 1-like

multiple interactions
increases phosphorylation
increases expression
affects localization

4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and affects the localization of DNM1L protein]; 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased phosphorylation of DNM1L protein]; alpha-Chlorohydrin results in increased expression of and affects the localization of DNM1L protein; Diosgenin affects the reaction [alpha-Chlorohydrin affects the localization of DNM1L protein]
4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of DNM1L protein]; alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of DNM1L protein; Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of DNM1L protein]

PMID:33651226 PMID:35149085

NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482

G

2'-deoxynucleoside 5'-phosphate N-hydrolase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of DNPH1 protein

NCBI chr 9:14,481,296...14,484,034
Ensembl chr 9:14,481,066...14,484,022

G

dedicator of cytokinesis 2

decreases expression

alpha-Chlorohydrin results in decreased expression of DOCK2 mRNA

NCBI chr10:18,827,237...19,244,832
Ensembl chr10:18,827,239...19,244,808

G

dedicator of cytokinesis 9

increases expression

alpha-Chlorohydrin results in increased expression of DOCK9 protein

NCBI chr15:98,611,518...98,883,306
Ensembl chr15:98,618,084...98,883,153

G

docking protein 1

increases expression

alpha-Chlorohydrin results in increased expression of DOK1 protein

NCBI chr 4:115,537,453...115,540,464
Ensembl chr 4:115,537,462...115,540,465

G

diphthamide biosynthesis 2

increases expression

alpha-Chlorohydrin results in increased expression of DPH2 protein

NCBI chr 5:131,428,434...131,431,394
Ensembl chr 5:131,428,268...131,431,395

G

diphthamide biosynthesis 5

increases expression

alpha-Chlorohydrin results in increased expression of DPH5 protein

NCBI chr 2:203,804,620...203,858,196
Ensembl chr 2:203,804,936...203,840,433

G

dipeptidylpeptidase 7

increases expression

alpha-Chlorohydrin results in increased expression of DPP7 mRNA

NCBI chr 3:8,165,091...8,169,343
Ensembl chr 3:8,165,091...8,169,355

G

dihydropyrimidinase

increases expression
decreases expression

alpha-Chlorohydrin analog results in increased expression of DPYS protein; alpha-Chlorohydrin results in increased expression of DPYS protein
alpha-Chlorohydrin results in decreased expression of DPYS protein

PMID:26597043 PMID:34915118

NCBI chr 7:70,822,648...70,929,255
Ensembl chr 7:70,835,789...70,929,231

G

DNA damage regulated autophagy modulator 2

increases expression

alpha-Chlorohydrin results in increased expression of DRAM2 mRNA

NCBI chr 2:194,035,624...194,064,415
Ensembl chr 2:194,035,818...194,063,403

G

Dr1 associated protein 1

increases expression

alpha-Chlorohydrin results in increased expression of DRAP1 protein

NCBI chr 1:202,731,775...202,734,468
Ensembl chr 1:202,731,788...202,734,425

G

dermatan sulfate epimerase-like

increases expression

alpha-Chlorohydrin results in increased expression of DSEL mRNA

NCBI chr13:186,413...192,592
Ensembl chr13:175,805...192,647

G

desmoplakin

increases expression

alpha-Chlorohydrin results in increased expression of DSP protein

NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800

G

dual specificity phosphatase 12

increases expression

alpha-Chlorohydrin results in increased expression of DUSP12 mRNA

NCBI chr13:83,122,192...83,131,800
Ensembl chr13:83,122,193...83,131,285

G

dual specificity phosphatase 6

decreases expression

alpha-Chlorohydrin results in decreased expression of DUSP6 mRNA

NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185

G

dual specificity phosphatase 7

increases expression

alpha-Chlorohydrin results in increased expression of DUSP7 mRNA

NCBI chr 8:107,009,369...107,016,404
Ensembl chr 8:107,008,528...107,016,404

G

dynein cytoplasmic 1 intermediate chain 2

increases expression

alpha-Chlorohydrin results in increased expression of DYNC1I2 protein

NCBI chr 3:56,033,882...56,085,080
Ensembl chr 3:56,033,917...56,085,080

G

dynein, cytoplasmic 1 light intermediate chain 2

increases expression

alpha-Chlorohydrin results in increased expression of DYNC1LI2 protein

NCBI chr19:531,783...554,670
Ensembl chr19:531,812...554,670

G

dynein light chain Tctex-type 1

increases expression

alpha-Chlorohydrin results in increased expression of DYNLT1 protein

NCBI chr 1:46,887,017...46,893,956
Ensembl chr 1:46,887,017...46,893,881

G

enoyl-CoA hydratase, short chain 1

increases expression

alpha-Chlorohydrin results in increased expression of ECHS1 mRNA

NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884

G

enoyl-CoA delta isomerase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of ECI1 protein

NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061

G

extracellular matrix protein 1

increases expression

alpha-Chlorohydrin results in increased expression of ECM1 mRNA

NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671

G

ER degradation enhancing alpha-mannosidase like protein 3

increases expression

alpha-Chlorohydrin results in increased expression of EDEM3 protein

NCBI chr13:63,858,282...63,920,538
Ensembl chr13:63,858,716...63,920,523

G

erythroid differentiation regulatory factor 1

increases expression

alpha-Chlorohydrin results in increased expression of EDRF1 mRNA

NCBI chr 1:188,441,514...188,478,743
Ensembl chr 1:188,441,634...188,478,701

G

EEF1A lysine methyltransferase 3

increases expression

alpha-Chlorohydrin results in increased expression of EEF1AKMT3 mRNA

NCBI chr 7:62,853,304...62,864,558
Ensembl chr 7:62,854,899...62,864,617

G

eukaryotic translation elongation factor 1 delta

increases expression

alpha-Chlorohydrin results in increased expression of EEF1D protein

NCBI chr 7:107,581,930...107,596,735
Ensembl chr 7:107,581,930...107,608,799

G

eukaryotic translation elongation factor 1 epsilon 1

increases expression

alpha-Chlorohydrin results in increased expression of EEF1E1 protein

NCBI chr17:26,148,652...26,159,358
Ensembl chr17:26,148,633...26,215,720

G

eukaryotic translation elongation factor 1 gamma

decreases expression
increases expression

alpha-Chlorohydrin analog results in decreased expression of EEF1G protein; alpha-Chlorohydrin results in decreased expression of EEF1G protein
alpha-Chlorohydrin results in increased expression of EEF1G protein

PMID:26072098 PMID:34915118

NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382

G

eukaryotic translation elongation factor 2

increases expression
decreases expression

alpha-Chlorohydrin results in increased expression of EEF2 protein
alpha-Chlorohydrin analog results in decreased expression of EEF2 protein

PMID:26072098 PMID:26597043

NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183

G

eukaryotic elongation factor, selenocysteine-tRNA-specific

increases expression

alpha-Chlorohydrin results in increased expression of EEFSEC protein

NCBI chr 4:120,719,616...120,915,779
Ensembl chr 4:120,707,133...120,915,779

G

EF-hand calcium binding domain 5

increases expression

alpha-Chlorohydrin results in increased expression of EFCAB5 mRNA

NCBI chr10:61,926,419...62,042,745
Ensembl chr10:61,926,953...62,042,749

G

epidermal growth factor

multiple interactions

[alpha-Chlorohydrin co-treated with glycidol] results in decreased expression of EGF mRNA

NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064

G

epidermal growth factor receptor

increases expression

alpha-Chlorohydrin results in increased expression of EGFR mRNA

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

G

early growth response 1

increases expression
decreases expression

alpha-Chlorohydrin results in increased expression of EGR1 mRNA
alpha-Chlorohydrin results in decreased expression of EGR1 mRNA

PMID:14644096 PMID:28522335

NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766

G

EH domain binding protein 1

increases expression

alpha-Chlorohydrin results in increased expression of EHBP1 protein

NCBI chr14:96,093,327...96,380,502
Ensembl chr14:96,093,327...96,345,332

G

EH domain binding protein 1-like 1

increases expression

alpha-Chlorohydrin results in increased expression of EHBP1L1 protein

NCBI chr 1:202,994,115...203,014,320
Ensembl chr 1:202,994,118...203,014,270

G

EH-domain containing 4

decreases expression

alpha-Chlorohydrin results in decreased expression of EHD4 mRNA

NCBI chr 3:107,058,191...107,121,985
Ensembl chr 3:107,058,958...107,122,002

G

eukaryotic translation initiation factor 2A

increases expression

alpha-Chlorohydrin results in increased expression of EIF2A protein

NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068

G

eukaryotic translation initiation factor 2-alpha kinase 2

increases expression

alpha-Chlorohydrin results in increased expression of EIF2AK2 protein

NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971

G

eukaryotic translation initiation factor 2 alpha kinase 3

multiple interactions

4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of EIF2AK3 protein]; alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of EIF2AK3 protein

NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911

G

eukaryotic translation initiation factor 2B subunit beta

increases expression

alpha-Chlorohydrin results in increased expression of EIF2B2 protein

NCBI chr 6:104,866,926...104,873,351
Ensembl chr 6:104,866,753...104,873,353

G

eukaryotic translation initiation factor 2B subunit gamma

increases expression

alpha-Chlorohydrin results in increased expression of EIF2B3 protein

NCBI chr 5:130,492,167...130,558,692
Ensembl chr 5:130,492,220...130,563,332

G

eukaryotic translation initiation factor 2B subunit delta

increases expression

alpha-Chlorohydrin results in increased expression of EIF2B4 protein

NCBI chr 6:25,183,177...25,188,832
Ensembl chr 6:25,183,186...25,188,829

G

eukaryotic translation initiation factor 2 subunit alpha

increases phosphorylation
multiple interactions

alpha-Chlorohydrin results in increased phosphorylation of EIF2S1 protein
4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of EIF2S1 protein]; alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of EIF2S1 protein

NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225

G

eukaryotic translation initiation factor 2 subunit beta

increases expression

alpha-Chlorohydrin results in increased expression of EIF2S2 protein

NCBI chr 3:143,374,652...143,395,460
Ensembl chr 3:143,373,686...143,395,432

G

eukaryotic translation initiation factor 3, subunit G

increases expression

alpha-Chlorohydrin results in increased expression of EIF3G protein

NCBI chr 8:19,429,728...19,433,760
Ensembl chr 8:19,429,643...19,433,808

G

eukaryotic translation initiation factor 3, subunit I

decreases expression

alpha-Chlorohydrin analog results in decreased expression of EIF3I protein; alpha-Chlorohydrin results in decreased expression of EIF3I protein

NCBI chr 5:141,935,135...141,942,589
Ensembl chr 5:141,935,044...141,942,676

G

eukaryotic translation initiation factor 4B

increases expression

alpha-Chlorohydrin results in increased expression of EIF4B protein

NCBI chr 7:133,206,637...133,228,436

G

eukaryotic translation initiation factor 4E binding protein 1

decreases phosphorylation
multiple interactions

alpha-Chlorohydrin results in decreased phosphorylation of EIF4EBP1 protein
3-methyladenine inhibits the reaction [Diosgenin promotes the reaction [alpha-Chlorohydrin results in decreased phosphorylation of EIF4EBP1 protein]]; Diosgenin promotes the reaction [alpha-Chlorohydrin results in decreased phosphorylation of EIF4EBP1 protein]

NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984

G

eukaryotic translation initiation factor 6

increases expression

alpha-Chlorohydrin results in increased expression of EIF6 protein

NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401

G

ELOVL fatty acid elongase 2

increases expression

alpha-Chlorohydrin results in increased expression of ELOVL2 mRNA

NCBI chr17:23,544,598...23,584,855
Ensembl chr17:23,544,568...23,584,848

G

ELOVL fatty acid elongase 6

increases expression

alpha-Chlorohydrin results in increased expression of ELOVL6 mRNA

NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186

G

embigin

decreases expression

alpha-Chlorohydrin results in decreased expression of EMB mRNA

NCBI chr 2:49,070,509...49,125,042
Ensembl chr 2:49,069,087...49,125,050

G

ER membrane protein complex subunit 2

increases expression

alpha-Chlorohydrin results in increased expression of TTC35 protein

NCBI chr 7:74,587,196...74,624,163
Ensembl chr 7:74,587,175...74,625,189

G

ER membrane protein complex subunit 7

increases expression

alpha-Chlorohydrin results in increased expression of EMC7 protein

NCBI chr 3:99,263,933...99,274,365
Ensembl chr 3:99,263,980...99,274,360

G

endomucin

decreases expression

alpha-Chlorohydrin results in decreased expression of EMCN mRNA

NCBI chr 2:225,891,100...225,970,932
Ensembl chr 2:225,891,100...225,970,929

G

EMG1 N1-specific pseudouridine methyltransferase

increases expression

alpha-Chlorohydrin results in increased expression of EMG1 protein

NCBI chr 4:157,509,258...157,517,540
Ensembl chr 4:157,509,277...157,517,540

G

endonuclease G

increases expression

alpha-Chlorohydrin results in increased expression of ENDOG protein

NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932

G

endoglin

increases expression

alpha-Chlorohydrin results in increased expression of ENG protein

NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230

G

enolase 1

affects expression
decreases expression

alpha-Chlorohydrin analog affects the expression of ENO1 protein
alpha-Chlorohydrin results in decreased expression of ENO1 protein

NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336

G

ecto-NOX disulfide-thiol exchanger 1

decreases expression

alpha-Chlorohydrin results in decreased expression of ENOX1 mRNA

NCBI chr15:52,517,833...53,079,752
Ensembl chr15:52,515,178...53,079,749

G

ectonucleotide pyrophosphatase/phosphodiesterase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of ENPP1 protein

NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715

G

ectonucleotide pyrophosphatase/phosphodiesterase 2

increases expression

alpha-Chlorohydrin results in increased expression of ENPP2 mRNA

NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827

G

ectonucleoside triphosphate diphosphohydrolase 2

increases expression

alpha-Chlorohydrin results in increased expression of ENTPD2 protein

NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866

G

erythrocyte membrane protein band 4.1-like 3

increases expression

alpha-Chlorohydrin results in increased expression of EPB41L3 mRNA

NCBI chr 9:109,056,178...109,260,607
Ensembl chr 9:109,016,113...109,260,607

G

epoxide hydrolase 1

increases expression

alpha-Chlorohydrin results in increased expression of EPHX1 mRNA; alpha-Chlorohydrin results in increased expression of EPHX1 protein

PMID:28522335 PMID:34915118

NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235

G

glutamyl-prolyl-tRNA synthetase 1

increases expression

alpha-Chlorohydrin results in increased expression of EPRS1 protein

NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966

G

epidermal growth factor receptor pathway substrate 15

increases expression

alpha-Chlorohydrin results in increased expression of EPS15 protein

NCBI chr 5:124,045,865...124,146,221
Ensembl chr 5:124,045,926...124,146,221

G

EGFR pathway substrate 8, signaling adaptor

increases expression

alpha-Chlorohydrin results in increased expression of EPS8 mRNA

NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873

G

Era-like 12S mitochondrial rRNA chaperone 1

increases expression

alpha-Chlorohydrin results in increased expression of ERAL1 protein

NCBI chr10:62,961,725...62,968,747
Ensembl chr10:62,961,730...62,968,994

G

endoplasmic reticulum aminopeptidase 1

increases expression

alpha-Chlorohydrin results in increased expression of ERAP1 protein

NCBI chr 2:3,931,817...3,970,735
Ensembl chr 2:3,931,904...3,972,447

G

erb-b2 receptor tyrosine kinase 4

decreases expression

alpha-Chlorohydrin results in decreased expression of ERBB4 mRNA

NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595

G

endoplasmic reticulum lectin 1

increases expression

alpha-Chlorohydrin results in increased expression of ERLEC1 protein

NCBI chr14:104,655,745...104,693,508
Ensembl chr14:104,655,673...104,693,480

G

endoplasmic reticulum to nucleus signaling 1

increases expression
multiple interactions

alpha-Chlorohydrin results in increased expression of ERN1 mRNA
4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of ERN1 protein]; alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of ERN1 protein

PMID:28522335 PMID:33651226

NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029

G

endoplasmic reticulum oxidoreductase 1 alpha

decreases expression

alpha-Chlorohydrin results in decreased expression of ERO1A protein

NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478

G

endoplasmic reticulum oxidoreductase 1 beta

increases expression

alpha-Chlorohydrin results in increased expression of ERO1B protein

NCBI chr17:85,861,086...86,003,244
Ensembl chr17:85,929,618...86,003,398

G

ERBB receptor feedback inhibitor 1

increases expression

alpha-Chlorohydrin results in increased expression of ERRFI1 mRNA

NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282

G

endothelial cell-specific molecule 1

decreases expression

alpha-Chlorohydrin results in decreased expression of ESM1 mRNA

NCBI chr 2:44,876,067...44,884,805
Ensembl chr 2:44,876,067...44,884,804

G

extra spindle pole bodies like 1, separase

increases expression

alpha-Chlorohydrin results in increased expression of ESPL1 mRNA

NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984

G

ETHE1, persulfide dioxygenase

increases expression

alpha-Chlorohydrin results in increased expression of ETHE1 mRNA

NCBI chr 1:80,184,037...80,199,092
Ensembl chr 1:80,183,894...80,199,052

G

ecotropic viral integration site 2B

affects expression

alpha-Chlorohydrin affects the expression of EVI2B mRNA

NCBI chr10:64,472,693...64,474,311
Ensembl chr10:64,471,505...64,481,560

G

exonuclease 3'-5' domain containing 2

increases expression

alpha-Chlorohydrin results in increased expression of EXD2 protein

NCBI chr 6:100,116,867...100,150,452
Ensembl chr 6:100,116,867...100,150,442

G

exocyst complex component 3

increases expression

alpha-Chlorohydrin results in increased expression of EXOC3 protein

NCBI chr 1:29,091,298...29,122,056
Ensembl chr 1:29,091,294...29,122,045

G

exosome component 7

increases expression

alpha-Chlorohydrin results in increased expression of EXOSC7 protein

NCBI chr 8:122,773,607...122,798,943
Ensembl chr 8:122,773,591...122,799,270

G

coagulation factor XIII B chain

increases expression

alpha-Chlorohydrin results in increased expression of F13B mRNA

NCBI chr13:51,130,908...51,156,383
Ensembl chr13:51,130,920...51,156,381

G

coagulation factor II (thrombin) receptor

decreases expression

alpha-Chlorohydrin results in decreased expression of F2R mRNA

NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870

G

fatty acid binding protein 4

decreases expression

alpha-Chlorohydrin results in decreased expression of FABP4 mRNA

NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578

G

fatty acid desaturase 3

increases expression

alpha-Chlorohydrin results in increased expression of FADS3 protein

NCBI chr 1:206,685,667...206,702,538
Ensembl chr 1:206,685,894...206,704,769

G

Fas associated factor family member 2

increases expression

alpha-Chlorohydrin results in increased expression of FAF2 protein

NCBI chr17:9,947,211...9,989,474
Ensembl chr17:9,947,220...9,989,485

G

fumarylacetoacetate hydrolase domain containing 1

decreases expression

alpha-Chlorohydrin analog results in decreased expression of FAHD1 protein

NCBI chr10:13,873,539...13,874,978
Ensembl chr10:13,873,527...13,875,012

G

family with sequence similarity 136, member A

increases expression

alpha-Chlorohydrin results in increased expression of FAM136A protein

NCBI chr 4:118,805,129...118,811,046
Ensembl chr 4:118,805,127...118,811,047

G

family with sequence similarity 151, member A

increases expression

alpha-Chlorohydrin results in increased expression of FAM151A mRNA

NCBI chr 5:121,514,804...121,527,555
Ensembl chr 5:121,514,804...121,527,555

G

family with sequence similarity 169, member A

increases expression

alpha-Chlorohydrin results in increased expression of FAM169A mRNA

NCBI chr 2:28,384,162...28,441,361
Ensembl chr 2:28,383,784...28,438,910

G

family with sequence similarity 170, member B

decreases expression

alpha-Chlorohydrin results in decreased expression of FAM170B mRNA

NCBI chr16:8,101,914...8,104,724
Ensembl chr16:8,101,914...8,104,705

G

family with sequence similarity 229, member A

decreases expression

alpha-Chlorohydrin results in decreased expression of FAM229A mRNA

NCBI chr 5:141,829,716...141,830,705
Ensembl chr 5:141,828,664...141,830,705

G

family with sequence similarity 43, member A

decreases expression

alpha-Chlorohydrin results in decreased expression of FAM43A mRNA

NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401

G

family with sequence similarity 78, member A

decreases expression

alpha-Chlorohydrin results in decreased expression of FAM78A mRNA

NCBI chr 3:15,355,958...15,376,330
Ensembl chr 3:15,355,955...15,373,812

G

family with sequence similarity 83, member B

decreases expression

alpha-Chlorohydrin results in decreased expression of FAM83B mRNA

NCBI chr 8:77,287,351...77,363,795
Ensembl chr 8:77,287,351...77,363,795

G

family with sequence similarity 83, member G

increases expression

alpha-Chlorohydrin results in increased expression of FAM83G mRNA

NCBI chr10:46,363,029...46,388,030
Ensembl chr10:46,363,051...46,388,019

G

family with sequence similarity 98, member A

increases expression

alpha-Chlorohydrin results in increased expression of FAM98A protein

NCBI chr 6:19,874,082...19,888,744
Ensembl chr 6:19,874,071...19,888,742

G

FA complementation group A

increases expression

alpha-Chlorohydrin results in increased expression of FANCA mRNA

NCBI chr19:51,304,126...51,362,586
Ensembl chr19:51,304,021...51,362,527

G

FA complementation group B

increases expression

alpha-Chlorohydrin results in increased expression of FANCB mRNA

NCBI chr X:29,403,771...29,420,484
Ensembl chr X:29,403,771...29,420,192

G

FERM, ARH/RhoGEF and pleckstrin domain protein 1

increases expression

alpha-Chlorohydrin results in increased expression of FARP1 protein

NCBI chr15:98,124,304...98,363,299
Ensembl chr15:98,182,329...98,363,299

G

phenylalanyl-tRNA synthetase 2, mitochondrial

increases expression

alpha-Chlorohydrin results in increased expression of FARS2 protein

NCBI chr17:28,319,215...28,746,217
Ensembl chr17:28,319,280...28,746,337

G

Fas cell surface death receptor

increases expression

alpha-Chlorohydrin results in increased expression of FAS mRNA

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

G

Fas ligand

increases expression

alpha-Chlorohydrin results in increased expression of FASLG mRNA

NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215

G

FAST kinase domains 2

increases expression

alpha-Chlorohydrin results in increased expression of FASTKD2 protein

NCBI chr 9:65,166,148...65,188,184
Ensembl chr 9:65,168,228...65,188,174

G

FAST kinase domains 5

increases expression

alpha-Chlorohydrin results in increased expression of FASTKD5 mRNA

NCBI chr 3:117,830,219...117,847,707
Ensembl chr 3:117,830,083...117,847,820

G

FAU ubiquitin like and ribosomal protein S30 fusion

decreases expression

alpha-Chlorohydrin results in decreased expression of FAU mRNA

NCBI chr 1:203,350,226...203,351,741
Ensembl chr 1:203,350,189...203,351,742

G

fibrillarin

increases expression

alpha-Chlorohydrin results in increased expression of FBL protein

NCBI chr 1:83,469,832...83,478,932
Ensembl chr 1:83,469,832...83,478,932

G

fibrillin 1

increases expression

alpha-Chlorohydrin results in increased expression of FBN1 mRNA; alpha-Chlorohydrin results in increased expression of FBN1 protein

PMID:28522335 PMID:34915118

NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889

G

fructose-bisphosphatase 2

increases expression

alpha-Chlorohydrin results in increased expression of FBP2 protein

NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698

G

F-box protein 32

increases expression

alpha-Chlorohydrin results in increased expression of FBXO32 mRNA

NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436

G

F-box protein 4

increases expression

alpha-Chlorohydrin results in increased expression of FBXO4 protein

NCBI chr 2:53,174,798...53,187,792
Ensembl chr 2:53,174,798...53,187,792

G

Fc gamma receptor 2A

decreases expression

alpha-Chlorohydrin results in decreased expression of FCGR2A mRNA

NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967

G

FCH and double SH3 domains 1

increases expression

alpha-Chlorohydrin results in increased expression of FCHSD1 protein

NCBI chr18:29,793,899...29,804,533
Ensembl chr18:29,793,899...29,804,466

G

farnesyl diphosphate synthase

increases expression

alpha-Chlorohydrin analog results in increased expression of FDPS protein; alpha-Chlorohydrin results in increased expression of FDPS protein

NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776

G

ferredoxin reductase

decreases expression

alpha-Chlorohydrin results in decreased expression of FDXR protein

NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658

G

ferrochelatase

increases expression

alpha-Chlorohydrin results in increased expression of FECH protein

NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348

G

flap structure-specific endonuclease 1

increases expression

alpha-Chlorohydrin results in increased expression of FEN1 protein

NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003

G

FERRY endosomal RAB5 effector complex subunit 3

increases expression

alpha-Chlorohydrin results in increased expression of FERRY3 protein

NCBI chr 4:159,772,693...159,809,322
Ensembl chr 4:159,772,786...159,806,382

G

FGGY carbohydrate kinase domain containing

decreases expression

alpha-Chlorohydrin results in decreased expression of FGGY protein

NCBI chr 5:110,398,866...110,786,019
Ensembl chr 5:110,398,863...110,786,017

G

FHF complex subunit HOOK interacting protein 1B

increases expression

alpha-Chlorohydrin results in increased expression of FHIP1B protein

NCBI chr 1:159,718,679...159,748,449
Ensembl chr 1:159,726,004...159,748,408

G

fragile histidine triad diadenosine triphosphatase

decreases expression

alpha-Chlorohydrin results in decreased expression of FHIT mRNA

NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340

G

FGF1 intracellular binding protein

increases expression

alpha-Chlorohydrin results in increased expression of FIBP protein

NCBI chr 1:202,768,065...202,772,405
Ensembl chr 1:202,768,078...202,772,399

G

fission, mitochondrial 1

multiple interactions
increases expression

4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of FIS1 protein]; Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of FIS1 protein]

PMID:33651226 PMID:35149085

NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377

G

FKBP prolyl isomerase 10

increases expression

alpha-Chlorohydrin results in increased expression of FKBP10 protein

NCBI chr10:85,345,434...85,357,998
Ensembl chr10:85,346,126...85,427,330

G

FKBP prolyl isomerase 11

increases expression

alpha-Chlorohydrin results in increased expression of FKBP11 protein

NCBI chr 7:129,871,870...129,877,760
Ensembl chr 7:129,871,870...129,875,303

G

FKBP prolyl isomerase 9

increases expression

alpha-Chlorohydrin results in increased expression of FKBP9 mRNA

NCBI chr 4:86,106,256...86,156,723
Ensembl chr 4:86,106,282...86,156,721

G

FLII, actin remodeling protein

increases expression

alpha-Chlorohydrin results in increased expression of FLII protein

NCBI chr10:45,394,032...45,408,051
Ensembl chr10:45,394,032...45,407,970

G

filamin B

increases expression

alpha-Chlorohydrin results in increased expression of FLNB protein

NCBI chr15:16,961,999...17,095,059
Ensembl chr15:16,962,003...17,095,006

G

formation of mitochondrial complex V assembly factor 1

increases expression

alpha-Chlorohydrin results in increased expression of FMC1 protein

NCBI chr 4:67,274,104...67,282,140
Ensembl chr 4:67,274,104...67,282,140

G

flavin containing dimethylaniline monoxygenase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of FMO1 protein

NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647

G

flavin containing dimethylaniline monoxygenase 3

increases expression

alpha-Chlorohydrin results in increased expression of FMO3 mRNA

NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028

G

fructosamine 3 kinase

decreases expression

alpha-Chlorohydrin results in decreased expression of FN3K protein

NCBI chr10:106,700,670...106,715,903
Ensembl chr10:106,700,670...106,715,895

G

formin binding protein 1

increases expression

alpha-Chlorohydrin results in increased expression of FNBP1 protein

NCBI chr 3:14,309,067...14,424,378
Ensembl chr 3:14,309,640...14,424,881

G

folate hydrolase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of FOLH1 protein

NCBI chr 1:140,428,101...140,501,563
Ensembl chr 1:140,428,101...140,501,379

G

folate receptor alpha

increases expression

alpha-Chlorohydrin results in increased expression of FOLR1 mRNA

NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667

G

folate receptor beta

decreases expression

alpha-Chlorohydrin analog results in decreased expression of FOLR2 protein

NCBI chr 1:156,200,044...156,218,380
Ensembl chr 1:156,200,060...156,205,724

G

forkhead box A3

decreases expression

alpha-Chlorohydrin results in decreased expression of FOXA3 mRNA

NCBI chr 1:78,662,067...78,672,321
Ensembl chr 1:78,662,431...78,672,155

G

forkhead box C1

decreases expression

alpha-Chlorohydrin results in decreased expression of FOXC1 mRNA

NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803

G

Fraser extracellular matrix complex subunit 1

decreases expression

alpha-Chlorohydrin results in decreased expression of FRAS1 mRNA

NCBI chr14:12,791,407...13,200,862
Ensembl chr14:12,793,599...13,200,726

G

FRAS1 related extracellular matrix 2

decreases expression

alpha-Chlorohydrin results in decreased expression of FREM2 mRNA

NCBI chr 2:137,602,784...137,740,785
Ensembl chr 2:137,602,784...137,740,785

G

fyn-related Src family tyrosine kinase

increases expression

alpha-Chlorohydrin results in increased expression of FRK protein

NCBI chr20:38,265,416...38,371,038
Ensembl chr20:38,265,280...38,371,114

G

fibrous sheath interacting protein 1

decreases expression

alpha-Chlorohydrin analog results in decreased expression of FSIP1 protein; alpha-Chlorohydrin results in decreased expression of FSIP1 protein

NCBI chr 3:105,074,584...105,217,180
Ensembl chr 3:105,068,543...105,217,167

G

formimidoyltransferase cyclodeaminase

decreases expression

alpha-Chlorohydrin analog results in decreased expression of FTCD protein; alpha-Chlorohydrin results in decreased expression of FTCD protein

NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735

G

ferritin heavy chain 1

decreases expression

alpha-Chlorohydrin analog results in decreased expression of FTH1 protein

NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424

G

ferritin light chain 1

decreases expression

alpha-Chlorohydrin results in decreased expression of FTL1 protein

NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725

G

FtsJ RNA 2'-O-methyltransferase 3

increases expression

alpha-Chlorohydrin results in increased expression of FTSJ3 protein

NCBI chr10:91,180,945...91,187,389
Ensembl chr10:91,180,696...91,187,397

G

far upstream element binding protein 1

increases expression

alpha-Chlorohydrin results in increased expression of FUBP1 protein

NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602

G

far upstream element binding protein 3

increases expression

alpha-Chlorohydrin results in increased expression of FUBP3 protein

NCBI chr 3:14,855,527...14,904,540
Ensembl chr 3:14,855,557...14,904,540

G

alpha-L-fucosidase 1

increases expression

alpha-Chlorohydrin results in increased expression of FUCA1 mRNA

NCBI chr 5:148,152,718...148,169,972
Ensembl chr 5:148,152,700...148,169,972

G

fucose mutarotase

decreases expression

alpha-Chlorohydrin results in decreased expression of FUOM protein

NCBI chr 1:194,888,535...194,893,046
Ensembl chr 1:194,886,709...194,893,046

G

fucosyltransferase 8

decreases expression

alpha-Chlorohydrin results in decreased expression of FUT8 mRNA

NCBI chr 6:95,949,246...96,176,677
Ensembl chr 6:95,949,991...96,176,677

G

glucose-6-phosphate dehydrogenase

increases expression

alpha-Chlorohydrin results in increased expression of G6PD protein

NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801

G

gamma-aminobutyric acid type B receptor subunit 2

increases expression

alpha-Chlorohydrin results in increased expression of GABBR2 mRNA

NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104

G

gamma-aminobutyric acid type A receptor subunit beta 3

increases expression

alpha-Chlorohydrin results in increased expression of GABRB3 mRNA

NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961

G

gamma-aminobutyric acid type A receptor subunit gamma 1

increases expression

alpha-Chlorohydrin results in increased expression of GABRG1 mRNA

NCBI chr14:37,396,217...37,469,606
Ensembl chr14:37,396,294...37,635,956

G

growth arrest and DNA-damage-inducible, alpha

increases expression

alpha-Chlorohydrin results in increased expression of GADD45A mRNA

NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115

G

galactokinase 1

increases expression

alpha-Chlorohydrin results in increased expression of GALK1 protein

NCBI chr10:101,243,146...101,247,323
Ensembl chr10:101,235,994...101,247,337

G

galactose mutarotase

decreases expression

alpha-Chlorohydrin results in decreased expression of GALM protein

NCBI chr 6:14,837,540...14,889,484
Ensembl chr 6:14,837,548...14,889,310

G

guanidinoacetate N-methyltransferase

multiple interactions
decreases expression

[alpha-Chlorohydrin co-treated with glycidol] results in decreased expression of GAMT mRNA
alpha-Chlorohydrin results in decreased expression of GAMT protein

PMID:33187795 PMID:34915118

NCBI chr 7:9,448,590...9,451,413
Ensembl chr 7:9,448,628...9,451,778

G

glyceraldehyde-3-phosphate dehydrogenase

multiple interactions
decreases activity
decreases expression

[alpha-Chlorohydrin results in decreased activity of GAPDH protein] which results in decreased reduction of Arsenates
alpha-Chlorohydrin analog results in decreased expression of GAPDH protein; alpha-Chlorohydrin results in decreased expression of GAPDH protein

PMID:16322075 PMID:26597043

NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235

G

glyceraldehyde-3-phosphate dehydrogenase like 10

decreases expression

alpha-Chlorohydrin results in decreased expression of GAPDHL10 protein

NCBI chr16:15,370,290...15,371,300
Ensembl chr16:15,370,293...15,371,300

G

glyceraldehyde-3-phosphate dehydrogenase, spermatogenic

decreases expression

alpha-Chlorohydrin results in decreased expression of GAPDHS mRNA

NCBI chr 1:85,979,096...85,994,153
Ensembl chr 1:85,979,098...85,993,640

G

GTPase activating Rap/RanGAP domain-like 3

increases expression

alpha-Chlorohydrin results in increased expression of GARNL3 mRNA

NCBI chr 3:16,288,718...16,432,308
Ensembl chr 3:16,288,719...16,430,837

G

glycyl-tRNA synthetase 1

increases expression

alpha-Chlorohydrin results in increased expression of GARS1 protein

NCBI chr 4:84,171,596...84,212,609
Ensembl chr 4:84,171,596...84,212,609

G

growth arrest specific 5

decreases expression

alpha-Chlorohydrin results in decreased expression of GAS5 mRNA

NCBI chr13:73,303,611...73,306,932

G

golgi associated kinase 1B

increases expression

alpha-Chlorohydrin results in increased expression of GASK1B mRNA

NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:165,047,684...165,112,477

G

glucosylceramidase beta 3

decreases expression

alpha-Chlorohydrin results in decreased expression of GBA3 protein

NCBI chr14:60,574,974...60,721,411
Ensembl chr14:60,574,976...60,721,653

G

1,4-alpha-glucan branching enzyme 1

increases expression

alpha-Chlorohydrin results in increased expression of GBE1 protein

NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210

G

GTP cyclohydrolase I feedback regulator

decreases expression

alpha-Chlorohydrin results in decreased expression of GCHFR protein

NCBI chr 3:106,158,046...106,162,080
Ensembl chr 3:106,159,394...106,162,080

G

glucokinase

increases expression

alpha-Chlorohydrin results in increased expression of GCK mRNA

NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995

G

glucokinase regulator

increases expression

alpha-Chlorohydrin results in increased expression of GCKR protein

NCBI chr 6:25,044,592...25,075,834
Ensembl chr 6:25,045,100...25,075,654

G

glutamate-cysteine ligase, catalytic subunit

decreases expression

alpha-Chlorohydrin results in decreased expression of GCLC mRNA

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

GCN1 activator of EIF2AK4

increases expression

alpha-Chlorohydrin results in increased expression of GCN1 protein

NCBI chr12:40,991,512...41,052,661
Ensembl chr12:40,991,512...41,052,555

G

guanine deaminase

increases expression

alpha-Chlorohydrin results in increased expression of GDA mRNA; alpha-Chlorohydrin results in increased expression of GDA protein

PMID:28522335 PMID:34915118

NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416

G

glycerophosphodiester phosphodiesterase domain containing 1

increases expression

alpha-Chlorohydrin results in increased expression of GDPD1 protein

NCBI chr10:71,840,497...71,883,936
Ensembl chr10:71,840,497...71,883,850

G

gem (nuclear organelle) associated protein 4

increases expression

alpha-Chlorohydrin results in increased expression of GEMIN4 protein

NCBI chr10:61,062,420...61,073,529
Ensembl chr10:61,066,425...61,073,431
Ensembl chr10:61,066,425...61,073,431

G

gem (nuclear organelle) associated protein 5

increases expression

alpha-Chlorohydrin results in increased expression of GEMIN5 protein

NCBI chr10:42,295,729...42,342,902
Ensembl chr10:42,297,515...42,342,892

G

glutamine fructose-6-phosphate transaminase 1

increases expression

alpha-Chlorohydrin results in increased expression of GFPT1 protein

NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471

G

golgi associated, gamma adaptin ear containing, ARF binding protein 2

increases expression

alpha-Chlorohydrin results in increased expression of GGA2 protein

NCBI chr 1:176,552,046...176,585,332
Ensembl chr 1:176,552,046...176,585,361

G

gamma-glutamyl cyclotransferase

decreases expression

alpha-Chlorohydrin results in decreased expression of GGCT mRNA

NCBI chr 4:84,122,921...84,129,327
Ensembl chr 4:84,123,118...84,129,277

G

gametogenetin binding protein 1

decreases expression

alpha-Chlorohydrin analog results in decreased expression of GGNBP1 protein

NCBI chr20:5,109,849...5,116,185
Ensembl chr20:5,099,311...5,116,183

G

gamma-glutamyltransferase 5

increases expression

alpha-Chlorohydrin results in increased expression of GGT5 protein

NCBI chr20:13,043,255...13,071,523
Ensembl chr20:13,043,257...13,071,450

G

growth hormone inducible transmembrane protein

increases expression

alpha-Chlorohydrin results in increased expression of GHITM protein

NCBI chr16:12,885,551...12,897,887
Ensembl chr16:12,885,553...12,897,879

G

growth hormone receptor

increases expression

alpha-Chlorohydrin results in increased expression of GHR mRNA

NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735

G

GTPase, IMAP family member 8

decreases expression

alpha-Chlorohydrin analog results in decreased expression of GIMAP8 protein; alpha-Chlorohydrin results in decreased expression of GIMAP8 protein

NCBI chr 4:77,600,104...77,611,593
Ensembl chr 4:77,600,186...77,611,590

G

GIPC PDZ domain containing family, member 1

increases expression

alpha-Chlorohydrin results in increased expression of GIPC1 protein

NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997

G

galactosidase, beta 1

increases expression

alpha-Chlorohydrin results in increased expression of GLB1 protein

NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127

G

galactosidase, beta 1-like

increases expression

alpha-Chlorohydrin results in increased expression of GLB1L protein

NCBI chr 9:76,693,325...76,705,548
Ensembl chr 9:76,695,173...76,705,510

G

glycine decarboxylase

decreases expression

alpha-Chlorohydrin results in decreased expression of GLDC protein

NCBI chr 1:227,883,249...227,962,119
Ensembl chr 1:227,883,249...227,962,097

G

glomulin, FKBP associated protein

increases expression

alpha-Chlorohydrin results in increased expression of GLMN protein

NCBI chr14:2,187,144...2,231,295
Ensembl chr14:2,187,642...2,230,420

G

glycosylated lysosomal membrane protein

increases expression

alpha-Chlorohydrin results in increased expression of GLMP mRNA

NCBI chr 2:173,794,273...173,797,863
Ensembl chr 2:173,794,255...173,799,960

G

glyoxalase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of GLO1 protein

NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649

G

glyoxalase domain containing 4

increases expression

alpha-Chlorohydrin results in increased expression of GLOD4 mRNA

NCBI chr10:61,077,535...61,095,876
Ensembl chr10:61,066,421...61,095,898

G

glutaredoxin

increases expression

alpha-Chlorohydrin results in increased expression of GLRX mRNA

NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680

G

glutaredoxin 3

increases expression

alpha-Chlorohydrin results in increased expression of GLRX3 protein

NCBI chr 1:192,241,707...192,272,012
Ensembl chr 1:192,241,701...192,272,010

G

glutaminase

increases expression

alpha-Chlorohydrin results in increased expression of GLS mRNA; alpha-Chlorohydrin results in increased expression of GLS protein

PMID:28522335 PMID:34915118

NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900

G

glutaminase 2

increases expression

alpha-Chlorohydrin results in increased expression of GLS2 protein

NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426

G

glutamate-ammonia ligase

affects expression

alpha-Chlorohydrin affects the expression of GLUL protein; alpha-Chlorohydrin analog affects the expression of GLUL protein

NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108

G

glycine-N-acyltransferase

decreases expression

alpha-Chlorohydrin results in decreased expression of GLYAT protein

NCBI chr 1:209,704,213...209,724,949
Ensembl chr 1:209,704,268...209,724,942

G

Gem-interacting protein

increases expression

alpha-Chlorohydrin results in increased expression of GMIP protein

NCBI chr16:19,600,723...19,614,459
Ensembl chr16:19,600,723...19,614,027

G

G protein subunit alpha o1

increases expression

alpha-Chlorohydrin results in increased expression of GNAO1 mRNA

NCBI chr19:11,034,874...11,192,531
Ensembl chr19:11,035,956...11,192,493

G

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

increases expression

alpha-Chlorohydrin analog results in increased expression of GNE protein; alpha-Chlorohydrin results in increased expression of GNE protein

NCBI chr 5:58,267,189...58,307,396
Ensembl chr 5:58,267,210...58,307,499

G

G protein subunit gamma 7

decreases expression

alpha-Chlorohydrin results in decreased expression of GNG7 protein

NCBI chr 7:8,697,458...8,761,239
Ensembl chr 7:8,697,521...8,761,240

G

glycine N-methyltransferase

decreases expression

alpha-Chlorohydrin results in decreased expression of GNMT protein
alpha-Chlorohydrin results in decreased expression of GNMT mRNA

PMID:26597043 PMID:35690182

NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434

G

glucosamine-6-phosphate deaminase 1

increases expression

alpha-Chlorohydrin results in increased expression of GNPDA1 mRNA

NCBI chr18:30,165,435...30,177,462
Ensembl chr18:30,165,427...30,177,486

G

glucosamine-phosphate N-acetyltransferase 1

increases expression

alpha-Chlorohydrin results in increased expression of GNPNAT1 protein

NCBI chr15:18,596,180...18,608,854
Ensembl chr15:18,596,442...18,608,739

G

glucosamine (N-acetyl)-6-sulfatase

increases expression

alpha-Chlorohydrin results in increased expression of GNS mRNA

NCBI chr 7:56,889,148...56,923,173
Ensembl chr 7:56,889,232...56,923,151

G

golgin A2

increases expression

alpha-Chlorohydrin results in increased expression of GOLGA2 protein

NCBI chr 3:15,583,862...15,604,279
Ensembl chr 3:15,584,039...15,604,279

G

golgin A3

increases expression

alpha-Chlorohydrin results in increased expression of GOLGA3 protein

NCBI chr12:46,452,409...46,500,509
Ensembl chr12:46,454,870...46,500,509

G

golgin A4

increases expression

alpha-Chlorohydrin results in increased expression of GOLGA4 protein

NCBI chr 8:118,208,200...118,285,003

G

golgin B1

increases expression

alpha-Chlorohydrin results in increased expression of GOLGB1 protein

NCBI chr11:63,843,179...63,900,665
Ensembl chr11:63,843,986...63,900,770

G

glycoprotein V (platelet)

increases expression

alpha-Chlorohydrin results in increased expression of GP5 protein

NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705

G

glycerol-3-phosphate dehydrogenase 1

decreases expression

alpha-Chlorohydrin analog results in decreased expression of GPD1 protein; alpha-Chlorohydrin results in decreased expression of GPD1 protein

NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529

G

G protein-coupled receptor 31

decreases expression

alpha-Chlorohydrin results in decreased expression of GPR31 mRNA

NCBI chr 1:52,926,953...52,927,912

G

GPRIN family member 3

increases expression

alpha-Chlorohydrin results in increased expression of GPRIN3 mRNA

NCBI chr 4:88,572,062...88,657,369
Ensembl chr 4:88,563,607...88,657,429

G

glutamic--pyruvic transaminase

increases expression

alpha-Chlorohydrin results in increased expression of GPT protein

NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494

G

glutathione peroxidase 1

increases expression
decreases expression

alpha-Chlorohydrin results in increased expression of GPX1 mRNA
alpha-Chlorohydrin results in decreased expression of GPX1 protein

PMID:28522335 PMID:34915118

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

growth factor receptor bound protein 10

increases expression

alpha-Chlorohydrin results in increased expression of GRB10 mRNA

NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806

G

growth factor receptor bound protein 2

decreases expression

alpha-Chlorohydrin analog results in decreased expression of GRB2 protein

NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309

G

growth regulating estrogen receptor binding 1

increases expression

alpha-Chlorohydrin results in increased expression of GREB1 mRNA

NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633

G

glutamate ionotropic receptor kainate type subunit 3

decreases expression

alpha-Chlorohydrin results in decreased expression of GRIK3 mRNA

NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307

G

glutamate ionotropic receptor NMDA type subunit 3A

decreases expression

alpha-Chlorohydrin analog results in decreased expression of GRIN3A protein

NCBI chr 5:64,006,847...64,206,408
Ensembl chr 5:64,009,980...64,206,085

G

GRIP1 associated protein 1

decreases expression

alpha-Chlorohydrin analog results in decreased expression of GRIPAP1 protein

NCBI chr X:14,678,896...14,708,747
Ensembl chr X:14,678,898...14,708,679

G

granulin precursor

increases expression

alpha-Chlorohydrin results in increased expression of GRN mRNA

NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775

G

GrpE-like 1, mitochondrial

decreases expression

alpha-Chlorohydrin analog results in decreased expression of GRPEL1 protein

NCBI chr14:74,292,023...74,298,243
Ensembl chr14:74,292,023...74,298,200

G

growth hormone regulated TBC protein 1

decreases expression

alpha-Chlorohydrin results in decreased expression of GRTP1 protein

NCBI chr16:76,332,777...76,356,414
Ensembl chr16:76,283,103...76,354,440

G

gasdermin D

increases cleavage
multiple interactions

alpha-Chlorohydrin results in increased cleavage of GSDMD protein
Cyclosporine inhibits the reaction [ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of GSDMD protein]]; ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of GSDMD protein]

PMID:33187795 PMID:38373586

NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:107,542,083...107,547,055

G

G1 to S phase transition 1

increases expression

alpha-Chlorohydrin results in increased expression of GSPT1 mRNA

NCBI chr10:4,362,528...4,397,215
Ensembl chr10:4,362,510...4,397,198

G

glutathione synthetase

increases expression
decreases expression

alpha-Chlorohydrin analog results in increased expression of GSS protein; alpha-Chlorohydrin results in increased expression of GSS protein
alpha-Chlorohydrin results in decreased expression of GSS protein

PMID:26072098 PMID:26597043

NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198

G

glutathione S-transferase alpha 1

increases expression
decreases expression

alpha-Chlorohydrin results in increased expression of GSTA1 mRNA
alpha-Chlorohydrin results in decreased expression of GSTA1 protein

PMID:28522335 PMID:34915118

NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121

G

glutathione S-transferase alpha 2

decreases expression

alpha-Chlorohydrin analog results in decreased expression of GSTA2 protein

NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798

G

glutathione S-transferase alpha 3

increases expression
decreases expression

alpha-Chlorohydrin results in increased expression of GSTA3 mRNA
alpha-Chlorohydrin analog results in decreased expression of GSTA3 protein

PMID:26597043 PMID:28522335

NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240

G

glutathione S-transferase alpha 4

increases expression

alpha-Chlorohydrin results in increased expression of GSTA4 mRNA

NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182

G

glutathione S-transferase alpha 5

decreases expression

alpha-Chlorohydrin analog results in decreased expression of GSTA5 protein

NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472

G

glutathione S-transferase mu 1

increases expression

alpha-Chlorohydrin analog results in increased expression of GSTM1 protein

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

glutathione S-transferase mu 2

increases expression

alpha-Chlorohydrin results in increased expression of GSTM2 protein

PMID:26072098 PMID:34915118

NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961

G

glutathione S-transferase mu 4

increases expression

alpha-Chlorohydrin results in increased expression of GSTM4 mRNA; alpha-Chlorohydrin results in increased expression of GSTM4 protein

PMID:28522335 PMID:34915118

NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323

G

glutathione S-transferase, mu 5

decreases expression
increases expression

alpha-Chlorohydrin analog results in decreased expression of GSTM3 protein
alpha-Chlorohydrin results in increased expression of GSTM3 protein

PMID:26072098 PMID:26597043

NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553

G

glutathione S-transferase, mu 5-like

increases expression

alpha-Chlorohydrin results in increased expression of GSTM5 protein

NCBI chr 2:195,544,424...195,549,895
Ensembl chr 2:195,544,426...195,628,961

G

glutathione S-transferase pi 1

increases expression

alpha-Chlorohydrin results in increased expression of GSTP1 mRNA; alpha-Chlorohydrin results in increased expression of GSTP1 protein

PMID:28522335 PMID:34915118

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

glutathione S-transferase theta 1

increases expression

alpha-Chlorohydrin results in increased expression of GSTT1 mRNA

NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585

G

glutathione S-transferase theta 2

decreases expression

alpha-Chlorohydrin analog results in decreased expression of GSTT2 protein

NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288

G

general transcription factor IIF subunit 2

increases expression

alpha-Chlorohydrin results in increased expression of GTF2F2 protein

NCBI chr15:51,206,027...51,327,166
Ensembl chr15:51,206,031...51,327,253

G

general transcription factor IIH subunit 3

increases expression

alpha-Chlorohydrin results in increased expression of GTF2H3 protein

NCBI chr12:32,009,010...32,025,484
Ensembl chr12:32,009,014...32,025,497

G

GTP binding protein 10

increases expression

alpha-Chlorohydrin results in increased expression of GTPBP10 protein

NCBI chr 4:28,476,857...28,494,375
Ensembl chr 4:28,476,857...28,494,375

G

GTP binding protein 3

decreases expression

alpha-Chlorohydrin results in decreased expression of GTPBP3 protein

NCBI chr16:18,175,766...18,180,857
Ensembl chr16:18,175,766...18,180,857

G

glucuronidase, beta

increases expression

alpha-Chlorohydrin results in increased expression of GUSB protein

NCBI chr12:26,701,188...26,714,718
Ensembl chr12:26,697,951...26,726,905

G

granzyme A

decreases expression

alpha-Chlorohydrin results in decreased expression of GZMA mRNA

NCBI chr 2:44,740,569...44,752,502
Ensembl chr 2:44,740,569...44,752,493

G

granzyme B

increases expression

alpha-Chlorohydrin results in increased expression of GZMB mRNA

NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814

G

H1.0 linker histone

decreases expression

alpha-Chlorohydrin results in decreased expression of H1F0 mRNA

NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694

G

H1.5 linker histone, cluster member

increases expression

alpha-Chlorohydrin results in increased expression of H1F5 protein

NCBI chr17:42,726,132...42,727,162
Ensembl chr17:42,726,127...42,769,160

G

3-hydroxyanthranilate 3,4-dioxygenase

increases expression
decreases expression

alpha-Chlorohydrin analog results in increased expression of HAAO protein; alpha-Chlorohydrin results in increased expression of HAAO protein
alpha-Chlorohydrin results in decreased expression of HAAO protein

PMID:26597043 PMID:34915118

NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877

G

3-hydroxyacyl-CoA dehydratase 4

decreases expression

alpha-Chlorohydrin results in decreased expression of HACD4 mRNA

NCBI chr 5:102,887,597...102,915,376
Ensembl chr 5:102,887,588...102,915,338

G

hydroxyacyl-CoA dehydrogenase

decreases expression
increases expression

alpha-Chlorohydrin analog results in decreased expression of HADH protein; alpha-Chlorohydrin results in decreased expression of HADH protein
alpha-Chlorohydrin results in increased expression of HADH mRNA

PMID:26597043 PMID:28522335 PMID:34915118

NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353

G

histidine ammonia lyase

decreases expression

alpha-Chlorohydrin analog results in decreased expression of HAL protein

NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701

G

hydroxyacid oxidase 2

decreases expression

alpha-Chlorohydrin results in decreased expression of HAO2 protein

NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425

G

histidyl-tRNA synthetase 2, mitochondrial

increases expression

alpha-Chlorohydrin results in increased expression of HARS2 protein

NCBI chr18:28,398,790...28,408,075
Ensembl chr18:28,398,795...28,414,747

G

hepatitis A virus cellular receptor 1

increases expression
multiple interactions

alpha-Chlorohydrin analog results in increased expression of HAVCR1 mRNA; alpha-Chlorohydrin results in increased expression of HAVCR1 protein
alpha-Chlorohydrin promotes the reaction [glycidol results in increased expression of HAVCR1 protein]; glycidol promotes the reaction [alpha-Chlorohydrin results in increased expression of HAVCR1 protein]

PMID:29860048 PMID:33187795

NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698

G

HCLS1 associated protein X-1

increases expression

alpha-Chlorohydrin results in increased expression of HAX1 protein

NCBI chr 2:175,434,242...175,437,926
Ensembl chr 2:175,434,238...175,437,714

G

host cell factor C1

increases expression

alpha-Chlorohydrin results in increased expression of HCFC1 protein

NCBI chr X:151,687,779...151,712,688
Ensembl chr X:151,687,779...151,712,638

G

host cell factor C2

increases expression

alpha-Chlorohydrin results in increased expression of HCFC2 protein

NCBI chr 7:20,983,986...21,019,826
Ensembl chr 7:20,991,017...21,019,801

G

haloacid dehalogenase-like hydrolase domain containing 3

increases expression
decreases expression

alpha-Chlorohydrin analog results in increased expression of HDHD3 protein
alpha-Chlorohydrin results in decreased expression of HDHD3 protein

NCBI chr 5:75,951,308...75,954,775
Ensembl chr 5:75,946,013...75,955,266

G

high density lipoprotein binding protein

increases expression

alpha-Chlorohydrin results in increased expression of HDLBP protein

NCBI chr 9:93,948,099...94,018,040
Ensembl chr 9:93,949,913...94,018,048

G

HEAT repeat containing 1

increases expression

alpha-Chlorohydrin results in increased expression of HEATR1 protein

NCBI chr17:58,053,288...58,093,895
Ensembl chr17:58,051,700...58,093,948

G

hephaestin

decreases expression

alpha-Chlorohydrin results in decreased expression of HEPH protein

NCBI chr X:61,151,131...61,402,980
Ensembl chr X:61,296,345...61,402,980

G

hexosaminidase subunit alpha

increases expression

alpha-Chlorohydrin results in increased expression of HEXA mRNA

NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013

G

hexosaminidase subunit beta

increases expression

alpha-Chlorohydrin results in increased expression of HEXB mRNA

NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223

G

homogentisate 1, 2-dioxygenase

decreases expression

alpha-Chlorohydrin results in decreased expression of HGD protein

NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323

G

3-hydroxyisobutyryl-CoA hydrolase

increases expression

alpha-Chlorohydrin results in increased expression of HIBCH protein

NCBI chr 9:48,590,097...48,669,896
Ensembl chr 9:48,590,099...48,669,824

G

histone cell cycle regulator

decreases expression

alpha-Chlorohydrin results in decreased expression of HIRA protein

NCBI chr11:82,024,469...82,133,212
Ensembl chr11:82,024,469...82,133,529

G

hexokinase 1

decreases expression

alpha-Chlorohydrin results in decreased expression of HK1 mRNA

NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131