|
G |
Agr2 |
anterior gradient 2, protein disulphide isomerase family member |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of AGR2 mRNA |
CTD |
PMID:29621558 |
|
NCBI chr 6:55,465,782...55,487,087
Ensembl chr 6:55,465,782...55,487,714
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|
G |
Arc |
activity-regulated cytoskeleton-associated protein |
decreases expression |
EXP |
Sulfur Dioxide results in decreased expression of ARC mRNA |
CTD |
PMID:25534910 |
|
NCBI chr 7:115,907,097...115,911,059
Ensembl chr 7:115,907,097...115,910,541
|
|
G |
Areg |
amphiregulin |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of AREG mRNA |
CTD |
PMID:29621558 |
|
NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of BAX protein; [Sulfur Dioxide co-treated with sodium arsenite] results in increased expression of BAX mRNA |
CTD |
PMID:27521637 PMID:30195209 |
|
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
|
|
G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions decreases expression |
ISO |
[Sulfur Dioxide co-treated with sodium arsenite] results in decreased expression of BCL2 mRNA Sulfur Dioxide results in decreased expression of BCL2 mRNA |
CTD |
PMID:30195209 |
|
NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
|
|
G |
Becn1 |
beclin 1 |
multiple interactions |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein] |
CTD |
PMID:30503585 |
|
NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
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|
G |
Camk2a |
calcium/calmodulin-dependent protein kinase II alpha |
decreases expression |
EXP |
Sulfur Dioxide results in decreased expression of CAMK2A protein modified form |
CTD |
PMID:25534910 |
|
NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
|
|
G |
Capn1 |
calpain 1 |
multiple interactions |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CAPN1 protein] |
CTD |
PMID:30503585 |
|
NCBI chr 1:221,346,081...221,370,965
Ensembl chr 1:221,346,066...221,370,322
|
|
G |
Casp1 |
caspase 1 |
multiple interactions |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP1 protein modified form] |
CTD |
PMID:30503585 |
|
NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
|
|
G |
Casp12 |
caspase 12 |
multiple interactions |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased cleavage of CASP12 protein] |
CTD |
PMID:30503585 |
|
NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
|
|
G |
Casp3 |
caspase 3 |
multiple interactions decreases activity increases expression |
EXP ISO |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein modified form]; Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein; Sulfur Dioxide results in increased expression of and results in increased activity of CASP3 protein [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP3 mRNA Sulfur Dioxide results in decreased activity of CASP3 protein [Sulfur Dioxide co-treated with sodium arsenite] results in increased activity of CASP3 protein; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]]; JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]; Rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]]; Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein Sulfur Dioxide results in increased expression of CASP3 mRNA |
CTD |
PMID:19621461 PMID:21873648 PMID:26209559 PMID:30195209 PMID:30503585 PMID:31268311 |
|
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
|
|
G |
Casp8 |
caspase 8 |
increases expression multiple interactions |
EXP ISO |
Sulfur Dioxide results in increased expression of CASP8 mRNA [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP8 mRNA Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CASP8 protein modified form]; Sulfur Dioxide results in increased expression of and results in increased activity of CASP8 protein |
CTD |
PMID:19621461 PMID:30503585 PMID:31268311 |
|
NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
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|
G |
Casp9 |
caspase 9 |
increases expression multiple interactions |
EXP ISO |
Sulfur Dioxide results in increased expression of CASP9 mRNA [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP9 mRNA; [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of CASP9 mRNA Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP9 protein modified form]; Sulfur Dioxide results in increased expression of and results in increased activity of CASP9 protein |
CTD |
PMID:19621461 PMID:30503585 PMID:31268311 |
|
NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
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G |
Cat |
catalase |
decreases activity multiple interactions |
EXP |
Sulfur Dioxide results in decreased activity of CAT protein Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CAT mRNA] |
CTD |
PMID:10871429 PMID:30503585 |
|
NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
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G |
Ccl1 |
C-C motif chemokine ligand 1 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of CCL1 mRNA |
CTD |
PMID:29621558 |
|
NCBI chr10:69,534,976...69,537,836
Ensembl chr10:69,534,933...69,537,882
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|
G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases expression multiple interactions |
EXP |
Sulfur Dioxide results in increased expression of CCL2 protein Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA] |
CTD |
PMID:27565714 PMID:30503585 |
|
NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
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G |
Ccl20 |
C-C motif chemokine ligand 20 |
decreases expression |
EXP |
Sulfur Dioxide results in decreased expression of CCL20 protein |
CTD |
PMID:27565714 |
|
NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
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G |
Cdh2 |
cadherin 2 |
multiple interactions decreases expression |
ISO |
[Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of CDH2 protein Sulfur Dioxide results in decreased expression of CDH2 protein |
CTD |
PMID:27237588 |
|
NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
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G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
multiple interactions decreases expression increases expression |
EXP |
[Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of CDKN2A mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of CDKN2A protein; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of CDKN2A mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of CDKN2A protein] Sulfur Dioxide results in decreased expression of CDKN2A mRNA; Sulfur Dioxide results in decreased expression of CDKN2A protein Sulfur Dioxide results in increased expression of CDKN2A protein |
CTD |
PMID:19408242 PMID:19434695 PMID:20064080 |
|
NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
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G |
Clca1 |
chloride channel accessory 1 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of CLCA1 mRNA |
CTD |
PMID:29621558 |
|
NCBI chr 2:250,897,980...250,923,711
Ensembl chr 2:250,897,969...250,923,744
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G |
Cldn11 |
claudin 11 |
decreases expression multiple interactions |
ISO |
Sulfur Dioxide results in decreased expression of CLDN11 protein [Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of CLDN11 protein |
CTD |
PMID:27237588 |
|
NCBI chr 2:115,823,541...115,836,846
Ensembl chr 2:115,823,538...115,836,846
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G |
Cnr1 |
cannabinoid receptor 1 |
multiple interactions |
ISO |
CNR1 protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] |
CTD |
PMID:26209559 |
|
NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
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G |
Col11a1 |
collagen type XI alpha 1 chain |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of COL11A1 mRNA |
CTD |
PMID:29621558 |
|
NCBI chr 2:216,863,423...217,056,523
Ensembl chr 2:216,863,428...217,056,523
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G |
Cox4i1 |
cytochrome c oxidase subunit 4i1 |
increases expression |
EXP |
Sulfur Dioxide results in increased expression of COX4I1 mRNA |
CTD |
PMID:22677886 |
|
NCBI chr19:54,245,958...54,252,198
Ensembl chr19:54,245,950...54,252,225
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G |
Ctnna1 |
catenin alpha 1 |
multiple interactions decreases expression |
ISO |
[Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of CTNNA1 protein Sulfur Dioxide results in decreased expression of CTNNA1 protein |
CTD |
PMID:27237588 |
|
NCBI chr18:27,923,229...28,055,972
Ensembl chr18:27,923,572...28,055,960
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
increases expression |
EXP |
Sulfur Dioxide results in increased expression of CXCL1 protein |
CTD |
PMID:27565714 |
|
NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
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|
G |
Cxcl11 |
C-X-C motif chemokine ligand 11 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of CXCL11 mRNA |
CTD |
PMID:29621558 |
|
NCBI chr14:17,195,395...17,198,170
Ensembl chr14:17,195,014...17,198,291
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G |
Cycs |
cytochrome c, somatic |
multiple interactions |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CYCS protein] |
CTD |
PMID:30503585 |
|
NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
|
|
G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
decreases activity decreases expression |
EXP |
Sulfur Dioxide results in decreased activity of CYP1A1 protein Sulfur Dioxide results in decreased expression of CYP1A1 mRNA |
CTD |
PMID:16023800 |
|
NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
decreases activity decreases expression |
EXP |
Sulfur Dioxide results in decreased activity of CYP1A2 protein Sulfur Dioxide results in decreased expression of CYP1A2 mRNA |
CTD |
PMID:16023800 |
|
NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
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|
G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of DDIT3 mRNA |
CTD |
PMID:31268311 |
|
NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
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|
G |
Dlg4 |
discs large MAGUK scaffold protein 4 |
affects expression |
EXP |
Sulfur Dioxide affects the expression of DLG4 protein |
CTD |
PMID:25534910 |
|
NCBI chr10:56,625,845...56,655,543
Ensembl chr10:56,627,411...56,653,599
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|
G |
Dnm1l |
dynamin 1-like |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of DNM1L protein |
CTD |
PMID:27521637 |
|
NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
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|
G |
Dsg2 |
desmoglein 2 |
multiple interactions decreases expression |
ISO |
[Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of DSG2 mRNA; [Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of DSG2 protein Sulfur Dioxide results in decreased expression of DSG2 mRNA; Sulfur Dioxide results in decreased expression of DSG2 protein |
CTD |
PMID:27237588 |
|
NCBI chr18:15,579,322...15,637,720
Ensembl chr18:15,579,315...15,637,715
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G |
Edn1 |
endothelin 1 |
increases expression multiple interactions |
EXP ISO |
Sulfur Dioxide results in increased expression of EDN1 mRNA; Sulfur Dioxide results in increased expression of EDN1 protein [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of EDN1 protein |
CTD |
PMID:20083630 PMID:30090456 |
|
NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
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|
G |
Fis1 |
fission, mitochondrial 1 |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of FIS1 protein |
CTD |
PMID:27521637 |
|
NCBI chr12:22,750,485...22,765,324
Ensembl chr12:22,750,485...22,765,308
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
EXP |
[Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of FOS mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of FOS protein Sulfur Dioxide results in increased expression of FOS mRNA; Sulfur Dioxide results in increased expression of FOS protein |
CTD |
PMID:19408242 PMID:19434695 |
|
NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
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|
G |
Gja1 |
gap junction protein, alpha 1 |
decreases expression multiple interactions |
ISO |
Sulfur Dioxide results in decreased expression of GJA1 protein [Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of GJA1 protein |
CTD |
PMID:27237588 |
|
NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
|
|
G |
Got1 |
glutamic-oxaloacetic transaminase 1 |
multiple interactions |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT1 mRNA] |
CTD |
PMID:30503585 |
|
NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
|
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G |
Got2 |
glutamic-oxaloacetic transaminase 2 |
multiple interactions |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT2 mRNA] |
CTD |
PMID:30503585 |
|
NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
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|
G |
Gria1 |
glutamate ionotropic receptor AMPA type subunit 1 |
decreases expression |
EXP |
Sulfur Dioxide results in decreased expression of GRIA1 mRNA |
CTD |
PMID:25534910 |
|
NCBI chr10:42,441,723...42,760,200
Ensembl chr10:42,614,713...42,760,200
|
|
G |
Gria2 |
glutamate ionotropic receptor AMPA type subunit 2 |
decreases expression |
EXP |
Sulfur Dioxide results in decreased expression of GRIA2 mRNA |
CTD |
PMID:25534910 |
|
NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629
|
|
G |
Grin1 |
glutamate ionotropic receptor NMDA type subunit 1 |
decreases expression |
EXP |
Sulfur Dioxide results in decreased expression of GRIN1 mRNA |
CTD |
PMID:25534910 |
|
NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
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G |
Grin2a |
glutamate ionotropic receptor NMDA type subunit 2A |
decreases expression |
EXP |
Sulfur Dioxide results in decreased expression of GRIN2A mRNA |
CTD |
PMID:25534910 |
|
NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
|
|
G |
Grin2b |
glutamate ionotropic receptor NMDA type subunit 2B |
multiple interactions decreases expression increases cleavage |
EXP |
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased cleavage of GRIN2B protein] Sulfur Dioxide results in decreased expression of GRIN2B mRNA |
CTD |
PMID:21873648 PMID:25534910 |
|
NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
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|
G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 protein] |
CTD |
PMID:30503585 |
|
NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
|
|
G |
Hras |
HRas proto-oncogene, GTPase |
multiple interactions increases expression |
EXP |
[Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of HRAS mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of HRAS protein; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of HRAS mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of HRAS protein] Sulfur Dioxide results in increased expression of HRAS mRNA; Sulfur Dioxide results in increased expression of HRAS protein |
CTD |
PMID:19408242 PMID:20064080 |
|
NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
|
|
G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions |
EXP ISO |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HSPA5 protein] [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of HSPA5 mRNA |
CTD |
PMID:30503585 PMID:31268311 |
|
NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
|
|
G |
Icam1 |
intercellular adhesion molecule 1 |
increases expression multiple interactions |
EXP |
Sulfur Dioxide results in increased expression of ICAM1 mRNA; Sulfur Dioxide results in increased expression of ICAM1 protein Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA] |
CTD |
PMID:20083630 PMID:30503585 |
|
NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
|
|
G |
Ifng |
interferon gamma |
increases expression multiple interactions |
EXP ISO |
Sulfur Dioxide results in increased expression of IFNG protein [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of IFNG protein |
CTD |
PMID:27565714 PMID:29621558 |
|
NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
|
|
G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of IKBKB mRNA |
CTD |
PMID:31268311 |
|
NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
|
|
G |
Il10 |
interleukin 10 |
increases expression |
EXP |
Sulfur Dioxide results in increased expression of IL10 protein |
CTD |
PMID:27565714 |
|
NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
|
|
G |
Il13 |
interleukin 13 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of IL13 mRNA |
CTD |
PMID:29621558 |
|
NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
|
|
G |
Il17a |
interleukin 17A |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of IL17A protein |
CTD |
PMID:29621558 |
|
NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
|
|
G |
Il18 |
interleukin 18 |
increases expression |
EXP |
Sulfur Dioxide results in increased expression of IL18 protein |
CTD |
PMID:27565714 |
|
NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
|
|
G |
Il1b |
interleukin 1 beta |
increases expression multiple interactions |
EXP |
Sulfur Dioxide results in increased expression of IL1B protein Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein] |
CTD |
PMID:27565714 PMID:30503585 |
|
NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
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G |
Il2 |
interleukin 2 |
increases expression |
EXP |
Sulfur Dioxide results in increased expression of IL2 protein |
CTD |
PMID:27565714 |
|
NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
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G |
Il4 |
interleukin 4 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of IL4 protein |
CTD |
PMID:29621558 |
|
NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
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G |
Il6 |
interleukin 6 |
increases expression multiple interactions |
ISO EXP |
Sulfur Dioxide results in increased expression of IL6 protein [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased secretion of IL6 protein; [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased secretion of IL6 protein Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA] |
CTD |
PMID:20056584 PMID:27565714 PMID:30503585 PMID:31268311 |
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NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
EXP |
[Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of JUN mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of JUN protein Sulfur Dioxide results in increased expression of JUN mRNA; Sulfur Dioxide results in increased expression of JUN protein |
CTD |
PMID:19408242 PMID:19434695 |
|
NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
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G |
Kras |
KRAS proto-oncogene, GTPase |
increases expression |
EXP |
Sulfur Dioxide results in increased expression of KRAS mRNA; Sulfur Dioxide results in increased expression of KRAS protein |
CTD |
PMID:19434695 |
|
NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
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G |
Lhcgr |
luteinizing hormone/choriogonadotropin receptor |
multiple interactions decreases expression |
ISO |
[Sulfur Dioxide co-treated with sodium arsenite] results in decreased expression of LHCGR mRNA Sulfur Dioxide results in decreased expression of LHCGR mRNA |
CTD |
PMID:30195209 |
|
NCBI chr 6:12,493,182...12,554,482
Ensembl chr 6:12,493,943...12,554,439
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased lipidation of MAP1LC3B protein] |
CTD |
PMID:30503585 |
|
NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
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G |
Mfn1 |
mitofusin 1 |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MFN1 protein |
CTD |
PMID:27521637 |
|
NCBI chr 2:118,929,738...118,971,689
Ensembl chr 2:118,929,738...118,973,698
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G |
Mfn2 |
mitofusin 2 |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MFN2 protein |
CTD |
PMID:27521637 |
|
NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
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G |
Mir1224 |
microRNA 1224 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR1224 mRNA |
CTD |
PMID:31268311 |
|
NCBI chr11:83,992,628...83,992,712
Ensembl chr11:83,992,628...83,992,712
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G |
Mir1249 |
microRNA 1249 |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of MIR1249 mRNA |
CTD |
PMID:30090456 |
|
NCBI chr 7:125,861,192...125,861,311
Ensembl chr 7:125,861,192...125,861,311
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G |
Mir125a |
microRNA 125a |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR125A mRNA |
CTD |
PMID:31268311 |
|
NCBI chr 1:59,704,827...59,704,911
Ensembl chr 1:59,704,827...59,704,911
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G |
Mir146b |
microRNA 146b |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR146B mRNA |
CTD |
PMID:31268311 |
|
NCBI chr 1:266,089,488...266,089,575
Ensembl chr 1:266,089,488...266,089,575
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G |
Mir155 |
microRNA 155 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR155 mRNA |
CTD |
PMID:31268311 |
|
NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
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G |
Mir185 |
microRNA 185 |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR185 mRNA |
CTD |
PMID:30090456 |
|
NCBI chr11:86,812,702...86,812,781
Ensembl chr11:86,812,702...86,812,781
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G |
Mir186 |
microRNA 186 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR186 mRNA |
CTD |
PMID:31268311 |
|
NCBI chr 2:263,873,759...263,873,844
Ensembl chr 2:263,873,759...263,873,844
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G |
Mir205 |
microRNA 205 |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of MIR205 mRNA |
CTD |
PMID:30090456 |
|
NCBI chr13:112,233,283...112,233,390
Ensembl chr13:112,233,283...112,233,390
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G |
Mir21 |
microRNA 21 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR21 mRNA; [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR21 mRNA |
CTD |
PMID:31268311 |
|
NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
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G |
Mir210 |
microRNA 210 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR210 mRNA |
CTD |
PMID:31268311 |
|
NCBI chr 1:214,208,355...214,208,464
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G |
Mir30a |
microRNA 30a |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR30A mRNA |
CTD |
PMID:31268311 |
|
NCBI chr 9:29,542,635...29,542,705
Ensembl chr 9:29,542,635...29,542,705
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G |
Mir30e |
microRNA 30e |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of MIR30E mRNA |
CTD |
PMID:30090456 |
|
NCBI chr 5:139,702,872...139,702,963
Ensembl chr 5:139,702,872...139,702,963
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G |
Mir320a |
microRNA 320a |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR320A mRNA |
CTD |
PMID:31268311 |
|
NCBI chr15:52,134,276...52,134,357
Ensembl chr15:52,134,276...52,134,357
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G |
Mir342 |
microRNA 342 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR342 mRNA |
CTD |
PMID:31268311 |
|
NCBI chr 6:132,561,169...132,561,267
Ensembl chr 6:132,561,169...132,561,267
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G |
Mir34b |
microRNA 34b |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of MIR34B mRNA |
CTD |
PMID:30090456 |
|
NCBI chr 8:55,492,542...55,492,625
Ensembl chr 8:55,492,542...55,492,625
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G |
Mir374b |
microRNA 374b |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR374B mRNA |
CTD |
PMID:31268311 |
|
NCBI chr X:74,443,648...74,443,715
Ensembl chr X:74,443,648...74,443,715
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G |
Mir375 |
microRNA 375 |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR375 mRNA |
CTD |
PMID:30090456 |
|
NCBI chr 9:82,161,716...82,161,790
Ensembl chr 9:82,161,716...82,161,790
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G |
Mir425 |
microRNA 425 |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR425 mRNA |
CTD |
PMID:30090456 |
|
NCBI chr 8:117,354,821...117,354,903
Ensembl chr 8:117,354,821...117,354,903
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G |
Mir500 |
microRNA 500 |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR500 mRNA |
CTD |
PMID:30090456 |
|
NCBI chr X:16,121,332...16,121,411
Ensembl chr X:16,121,322...16,121,413
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G |
Mir503 |
microRNA 503 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR503 mRNA |
CTD |
PMID:31268311 |
|
NCBI chr X:158,148,476...158,148,546
Ensembl chr X:158,148,476...158,148,546
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G |
Mir615 |
microRNA 615 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR615 mRNA |
CTD |
PMID:31268311 |
|
NCBI chr 7:144,629,019...144,629,110
Ensembl chr 7:144,629,019...144,629,110
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G |
Mir93 |
microRNA 93 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR93 mRNA |
CTD |
PMID:31268311 |
|
NCBI chr12:19,307,543...19,307,629
Ensembl chr12:19,307,543...19,307,629
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G |
Mirlet7i |
microRNA let-7i |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIRLET7I mRNA |
CTD |
PMID:31268311 |
|
NCBI chr 7:66,802,731...66,802,815
Ensembl chr 7:66,802,732...66,802,821
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G |
Mpo |
myeloperoxidase |
multiple interactions |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein] |
CTD |
PMID:30503585 |
|
NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
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G |
Mt-atp6 |
mitochondrially encoded ATP synthase membrane subunit 6 |
increases expression decreases expression |
EXP |
Sulfur Dioxide results in increased expression of ATP6 mRNA Sulfur Dioxide results in decreased expression of ATP6 mRNA |
CTD |
PMID:22677886 PMID:26980303 |
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NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
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G |
Mt-atp8 |
mitochondrially encoded ATP synthase membrane subunit 8 |
increases expression decreases expression |
EXP |
Sulfur Dioxide results in increased expression of ATP8 mRNA Sulfur Dioxide results in decreased expression of ATP8 mRNA |
CTD |
PMID:22677886 PMID:26980303 |
|
NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961
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G |
Mt-co1 |
mitochondrially encoded cytochrome c oxidase I |
increases expression decreases expression |
EXP |
Sulfur Dioxide results in increased expression of COX1 mRNA Sulfur Dioxide results in decreased expression of COX1 mRNA |
CTD |
PMID:22677886 PMID:26980303 |
|
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
|
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G |
Mt-co2 |
mitochondrially encoded cytochrome c oxidase II |
decreases expression |
EXP |
Sulfur Dioxide results in decreased expression of COX2 mRNA |
CTD |
PMID:26980303 |
|
NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
|
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G |
Mt-co3 |
mitochondrially encoded cytochrome c oxidase III |
decreases expression |
EXP |
Sulfur Dioxide results in decreased expression of COX3 mRNA |
CTD |
PMID:26980303 |
|
NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
multiple interactions increases expression |
EXP |
[Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of MYC mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of MYC protein; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of MYC mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of MYC protein] Sulfur Dioxide results in increased expression of MYC mRNA; Sulfur Dioxide results in increased expression of MYC protein |
CTD |
PMID:19408242 PMID:19434695 PMID:20064080 |
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NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
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G |
Myd88 |
MYD88, innate immune signal transduction adaptor |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MYD88 mRNA |
CTD |
PMID:31268311 |
|
NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
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G |
Nos2 |
nitric oxide synthase 2 |
increases expression multiple interactions |
EXP |
Sulfur Dioxide results in increased expression of NOS2 mRNA; Sulfur Dioxide results in increased expression of NOS2 protein Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA] |
CTD |
PMID:20083630 PMID:30503585 |
|
NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
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G |
Nos3 |
nitric oxide synthase 3 |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of NOS3 protein |
CTD |
PMID:30090456 |
|
NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
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G |
Nrf1 |
nuclear respiratory factor 1 |
increases expression decreases expression |
EXP |
Sulfur Dioxide results in increased expression of NRF1 protein Sulfur Dioxide results in decreased expression of NRF1 mRNA; Sulfur Dioxide results in decreased expression of NRF1 protein |
CTD |
PMID:22677886 PMID:26980303 |
|
NCBI chr 4:57,335,732...57,445,317
Ensembl chr 4:57,378,069...57,445,341
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G |
Opa1 |
OPA1, mitochondrial dynamin like GTPase |
multiple interactions |
ISO |
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of OPA1 protein |
CTD |
PMID:27521637 |
|
NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803
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G |
Pla2g7 |
phospholipase A2 group VII |
affects expression |
ISO |
Sulfur Dioxide affects the expression of PLA2G7 |
CTD |
PMID:21356620 |
|
NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions decreases expression |
ISO |
glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in decreased expression of PPARG protein]; JZL 184 inhibits the reaction [Sulfur Dioxide results in decreased expression of PPARG protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] |
CTD |
PMID:26209559 |
|
NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
decreases expression |
EXP |
Sulfur Dioxide results in decreased expression of PPARGC1A mRNA; Sulfur Dioxide results in decreased expression of PPARGC1A protein |
CTD |
PMID:26980303 |
|
NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
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G |
Prg2 |
proteoglycan 2 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of PRG2 mRNA |
CTD |
PMID:29621558 |
|
NCBI chr 3:72,385,678...72,389,245
Ensembl chr 3:72,385,666...72,389,276
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G |
Ptger2 |
prostaglandin E receptor 2 |
increases expression multiple interactions |
EXP |
Sulfur Dioxide results in increased expression of PTGER2 protein N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased expression of PTGER2 protein] |
CTD |
PMID:21873648 |
|
NCBI chr15:19,336,029...19,349,759
Ensembl chr15:19,338,175...19,350,210
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G |
Ptger4 |
prostaglandin E receptor 4 |
multiple interactions increases expression |
EXP |
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased expression of PTGER4 protein] |
CTD |
PMID:21873648 |
|
NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression |
EXP ISO |
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein] 2-chloro-5-nitrobenzanilide inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]; JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; rimonabant inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]] Sulfur Dioxide results in increased expression of PTGS2 mRNA; Sulfur Dioxide results in increased expression of PTGS2 protein |
CTD |
PMID:20083630 PMID:21873648 PMID:26209559 |
|
NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
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G |
Rb1 |
RB transcriptional corepressor 1 |
multiple interactions decreases expression increases expression |
EXP |
[Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of RB1 mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of RB1 protein; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of RB1 mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of RB1 protein] Sulfur Dioxide results in decreased expression of RB1 mRNA; Sulfur Dioxide results in decreased expression of RB1 protein Sulfur Dioxide results in increased expression of RB1 protein |
CTD |
PMID:19408242 PMID:19434695 PMID:20064080 |
|
NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions increases phosphorylation |
ISO |
2-chloro-5-nitrobenzanilide inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]; glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]; JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]; rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] |
CTD |
PMID:26209559 |
|
NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
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|
G |
Shbg |
sex hormone binding globulin |
multiple interactions |
ISO |
[Sulfur Dioxide co-treated with sodium arsenite] results in decreased expression of SHBG mRNA |
CTD |
PMID:30195209 |
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NCBI chr10:56,219,861...56,237,354
Ensembl chr10:56,219,858...56,223,245
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G |
Sod1 |
superoxide dismutase 1 |
multiple interactions increases activity |
EXP |
Sulfur Dioxide inhibits the reaction [Alloxan results in decreased activity of SOD1 protein] Sulfur Dioxide results in increased activity of SOD1 protein |
CTD |
PMID:10871429 |
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NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
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G |
Sod2 |
superoxide dismutase 2 |
multiple interactions |
ISO |
[[Air Pollutants results in increased abundance of Sulfur Dioxide] which affects the methylation of SOD2 promoter] which affects the methylation of SOD2 promoter |
CTD |
PMID:31220783 |
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NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
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G |
Sostdc1 |
sclerostin domain containing 1 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of SOSTDC1 mRNA |
CTD |
PMID:29621558 |
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NCBI chr 6:55,812,820...55,816,994
Ensembl chr 6:55,812,747...55,817,066
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G |
Star |
steroidogenic acute regulatory protein |
multiple interactions |
ISO |
[Sulfur Dioxide co-treated with sodium arsenite] results in decreased expression of STAR mRNA |
CTD |
PMID:30195209 |
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NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
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G |
Syp |
synaptophysin |
affects expression |
EXP |
Sulfur Dioxide affects the expression of SYP protein |
CTD |
PMID:25534910 |
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NCBI chr X:15,694,699...15,709,244
Ensembl chr X:15,695,566...15,707,436
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G |
Tfam |
transcription factor A, mitochondrial |
increases expression decreases expression |
EXP |
Sulfur Dioxide results in increased expression of TFAM mRNA Sulfur Dioxide results in decreased expression of TFAM mRNA; Sulfur Dioxide results in decreased expression of TFAM protein |
CTD |
PMID:22677886 PMID:26980303 |
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NCBI chr20:18,594,057...18,606,106
Ensembl chr20:18,594,037...18,606,151
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G |
Tgfb1 |
transforming growth factor, beta 1 |
increases expression |
EXP |
Sulfur Dioxide results in increased expression of TGFB1 protein |
CTD |
PMID:27565714 |
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NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
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G |
Tlr2 |
toll-like receptor 2 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of TLR2 mRNA |
CTD |
PMID:31268311 |
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NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
EXP ISO |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein] [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased secretion of TNF protein; [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased secretion of TNF protein |
CTD |
PMID:30503585 PMID:31268311 |
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NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 Ensembl chr20:5,189,390...5,192,000
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G |
Tnfsf4 |
TNF superfamily member 4 |
multiple interactions |
ISO |
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of TNFSF4 mRNA |
CTD |
PMID:29621558 |
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NCBI chr13:79,269,973...79,293,775
Ensembl chr13:79,269,973...79,293,778
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G |
Tp53 |
tumor protein p53 |
multiple interactions increases expression |
EXP ISO |
[Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of TP53 mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of TP53 protein; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of and results in increased activity of TP53 protein]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein] [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of TRP53 protein Sulfur Dioxide results in increased expression of TP53 mRNA; Sulfur Dioxide results in increased expression of TP53 protein |
CTD |
PMID:19408242 PMID:19434695 PMID:20064080 PMID:27521637 PMID:30503585 |
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NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA] |
CTD |
PMID:30503585 |
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NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
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