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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dermatan sulfate
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Accession:CHEBI:18376 term browser browse the term
Definition:Any of a group of glycosaminoglycans with repeating units consisting of variously sulfated beta1->4-linked L-iduronyl-(alpha1->3)-N-acetyl-D-galactosamine units.
Synonyms:related_synonym: Chondroitin sulfate B;   Dermatan L-iduronate;   Formula=H2O.(C14H20NO13S)n;   beta-Heparin
 alt_id: CHEBI:14127;   CHEBI:23644;   CHEBI:4440
 xref: Beilstein:8390617;   CAS:24967-94-0;   KEGG:C00426
 xref_mesh: MESH:D003871
 cyclic_relationship: is_conjugate_acid_of CHEBI:58465



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dermatan sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor affects binding ISO [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to BDNF protein CTD PMID:15385557 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G F2 coagulation factor II multiple interactions ISO [Dermatan Sulfate co-treated with SERPIND1 protein] results in decreased activity of F2 protein CTD PMID:11805133 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G Fgf10 fibroblast growth factor 10 affects binding ISO [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF10 protein CTD PMID:15385557 NCBI chr 2:50,801,897...50,875,428
Ensembl chr 2:50,800,992...50,876,866
JBrowse link
G Fgf16 fibroblast growth factor 16 affects binding EXP [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF16 protein CTD PMID:15385557 NCBI chr  X:70,816,658...70,827,270
Ensembl chr  X:70,817,433...70,878,717
JBrowse link
G Fgf18 fibroblast growth factor 18 affects binding ISO [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF18 protein CTD PMID:15385557 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818
JBrowse link
G Fgf2 fibroblast growth factor 2 affects binding
increases activity
ISO [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF2 protein
Dermatan Sulfate analog results in increased activity of FGF2 protein
CTD PMID:15385557 PMID:15563459 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgf23 fibroblast growth factor 23 increases activity ISO Dermatan Sulfate analog results in increased activity of FGF23 protein CTD PMID:16081635 NCBI chr 4:159,914,393...159,922,073
Ensembl chr 4:159,914,272...159,923,821
JBrowse link
G Fgf7 fibroblast growth factor 7 increases activity ISO Dermatan Sulfate analog results in increased activity of FGF7 protein CTD PMID:15563459 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
JBrowse link
G Gdnf glial cell derived neurotrophic factor affects binding ISO [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to GDNF protein CTD PMID:15385557 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Hbegf heparin-binding EGF-like growth factor affects binding ISO [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to HBEGF protein CTD PMID:15385557 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
JBrowse link
G Mdk midkine affects binding ISO [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to MDK protein CTD PMID:15385557 NCBI chr 3:77,901,156...77,903,997
Ensembl chr 3:77,901,158...77,903,130
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha decreases expression ISO Dermatan Sulfate results in decreased expression of PDGFRA mRNA CTD PMID:16945567 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta decreases expression ISO Dermatan Sulfate results in decreased expression of PDGFRB mRNA CTD PMID:16945567 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Ptn pleiotrophin affects binding ISO [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to PTN protein CTD PMID:15385557 NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456
JBrowse link
G Serpind1 serpin family D member 1 multiple interactions ISO [Dermatan Sulfate co-treated with SERPIND1 protein] results in decreased activity of F2 protein CTD PMID:11805133 NCBI chr11:83,664,517...83,675,593
Ensembl chr11:83,664,518...83,675,519
JBrowse link
G Vegfa vascular endothelial growth factor A affects binding ISO [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to VEGFA protein CTD PMID:15385557 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link

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  CHEBI ontology 20069
    role 20021
      application 19757
        pharmaceutical 19631
          drug 19631
            hematologic agent 4529
              dermatan sulfate 16
Path 2
Term Annotations click to browse term
  CHEBI ontology 20069
    subatomic particle 20068
      composite particle 20068
        hadron 20068
          baryon 20068
            nucleon 20068
              atomic nucleus 20068
                atom 20068
                  main group element atom 19969
                    p-block element atom 19969
                      carbon group element atom 19892
                        carbon atom 19885
                          organic molecular entity 19885
                            heteroorganic entity 19574
                              organochalcogen compound 19336
                                organooxygen compound 19236
                                  carbohydrates and carbohydrate derivatives 13956
                                    carbohydrate 13956
                                      polysaccharide 3231
                                        polysaccharide derivative 3211
                                          aminoglycan 399
                                            glycosaminoglycan 373
                                              mucopolysaccharide 347
                                                dermatan 16
                                                  dermatan sulfate 16
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