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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dermatan sulfate
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Accession:CHEBI:18376 term browser browse the term
Definition:Any of a group of glycosaminoglycans with repeating units consisting of variously sulfated beta1->4-linked L-iduronyl-(alpha1->3)-N-acetyl-D-galactosamine units.
Synonyms:related_synonym: Chondroitin sulfate B;   Dermatan L-iduronate;   Formula=H2O.(C14H20NO13S)n;   beta-Heparin
 alt_id: CHEBI:14127;   CHEBI:23644;   CHEBI:4440
 xref: Beilstein:8390617;   CAS:24967-94-0;   KEGG:C00426
 xref_mesh: MESH:D003871
 cyclic_relationship: is_conjugate_acid_of CHEBI:58465


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dermatan sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain derived neurotrophic factor affects binding ISO [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to BDNF protein CTD PMID:15385557 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352 		JBrowse link
G F2 coagulation factor II multiple interactions ISO [Dermatan Sulfate co-treated with SERPIND1 protein] results in decreased activity of F2 protein CTD PMID:11805133 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759 		JBrowse link
G Fgf10 fibroblast growth factor 10 affects binding ISO [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF10 protein CTD PMID:15385557 NCBI chr13:118,851,199...118,928,651
Ensembl chr13:118,806,327...118,928,651 		JBrowse link
G Fgf16 fibroblast growth factor 16 affects binding ISO [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF16 protein CTD PMID:15385557 NCBI chr  X:104,808,083...104,820,138
Ensembl chr  X:104,807,885...104,818,545 		JBrowse link
G Fgf18 fibroblast growth factor 18 affects binding EXP [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF18 protein CTD PMID:15385557 NCBI chr11:33,066,970...33,097,400
Ensembl chr11:33,067,430...33,097,400 		JBrowse link
G Fgf2 fibroblast growth factor 2 affects binding
increases activity		 ISO
EXP		 [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF2 protein
Dermatan Sulfate analog results in increased activity of FGF2 protein		 CTD PMID:15385557 PMID:15563459 NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257 		JBrowse link
G Fgf23 fibroblast growth factor 23 increases activity EXP Dermatan Sulfate analog results in increased activity of FGF23 protein CTD PMID:16081635 NCBI chr 6:127,049,865...127,059,257
Ensembl chr 6:127,049,865...127,058,371 		JBrowse link
G Fgf7 fibroblast growth factor 7 increases activity EXP Dermatan Sulfate analog results in increased activity of FGF7 protein CTD PMID:15563459 NCBI chr 2:125,876,578...125,933,105
Ensembl chr 2:125,876,578...125,933,105 		JBrowse link
G Gdnf glial cell line derived neurotrophic factor affects binding ISO [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to GDNF protein CTD PMID:15385557 NCBI chr15:7,839,529...7,867,061
Ensembl chr15:7,840,327...7,867,056 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor affects binding ISO [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to HBEGF protein CTD PMID:15385557 NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858 		JBrowse link
G Mdk midkine affects binding ISO [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to MDK protein CTD PMID:15385557 NCBI chr 2:91,760,149...91,762,348
Ensembl chr 2:91,760,150...91,762,642 		JBrowse link
G Pdgfra platelet derived growth factor receptor, alpha polypeptide decreases expression ISO Dermatan Sulfate results in decreased expression of PDGFRA mRNA CTD PMID:16945567 NCBI chr 5:75,311,988...75,358,867
Ensembl chr 5:75,312,953...75,358,876 		JBrowse link
G Pdgfrb platelet derived growth factor receptor, beta polypeptide decreases expression ISO Dermatan Sulfate results in decreased expression of PDGFRB mRNA CTD PMID:16945567 NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133 		JBrowse link
G Ptn pleiotrophin affects binding ISO [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to PTN protein CTD PMID:15385557 NCBI chr 6:36,691,863...36,787,114
Ensembl chr 6:36,691,864...36,787,155 		JBrowse link
G Serpind1 serine (or cysteine) peptidase inhibitor, clade D, member 1 multiple interactions ISO [Dermatan Sulfate co-treated with SERPIND1 protein] results in decreased activity of F2 protein CTD PMID:11805133 NCBI chr16:17,149,235...17,161,438
Ensembl chr16:17,149,235...17,161,439 		JBrowse link
G Vegfa vascular endothelial growth factor A affects binding ISO [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to VEGFA protein CTD PMID:15385557 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 22194
    role 22179
      application 21760
        pharmaceutical 21174
          drug 21174
            hematologic agent 5214
              dermatan sulfate 16
Path 2
Term Annotations click to browse term
  CHEBI ontology 22194
    subatomic particle 22186
      composite particle 22186
        hadron 22186
          baryon 22186
            nucleon 22186
              atomic nucleus 22186
                atom 22186
                  main group element atom 22120
                    p-block element atom 22120
                      carbon group element atom 21920
                        carbon atom 21846
                          organic molecular entity 21846
                            heteroorganic entity 21500
                              organochalcogen compound 20983
                                organooxygen compound 20824
                                  carbohydrates and carbohydrate derivatives 16042
                                    carbohydrate 16042
                                      polysaccharide 8715
                                        polysaccharide derivative 5437
                                          aminoglycan 408
                                            glycosaminoglycan 374
                                              mucopolysaccharide 349
                                                dermatan 16
                                                  dermatan sulfate 16
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