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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:14-demethyllanosterol
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Accession:CHEBI:18364 term browser browse the term
Definition:A 3beta-sterol formed formally by loss of a methyl group from the 14-position of lanosterol.
Synonyms:related_synonym: (3beta,5alpha)-4,4-dimethylcholesta-8,24-dien-3-ol;   14-desmethyllanosterol;   4,4-Dimethyl-5alpha-cholesta-8,24-dien-3beta-ol;   4,4-Dimethyl-8,24-cholestadienol;   4,4-dimethylcholesta-8(9),24-dien-3beta-ol;   4,4-dimethylzymosterol;   Formula=C29H48O;   InChI=1S/C29H48O/c1-19(2)9-8-10-20(3)22-12-13-23-21-11-14-25-27(4,5)26(30)16-18-29(25,7)24(21)15-17-28(22,23)6/h9,20,22-23,25-26,30H,8,10-18H2,1-7H3/t20-,22-,23+,25+,26+,28-,29-/m1/s1;   InChIKey=CHGIKSSZNBCNDW-QGBOJXOESA-N;   SMILES=C12=C([C@]3([C@]([C@](CC3)([C@@H](CCC=C(C)C)C)[H])(C)CC1)[H])CC[C@@]4([C@@]2(CC[C@@H](C4(C)C)O)C)[H]
 alt_id: CHEBI:11921;   CHEBI:19151;   CHEBI:755
 xref: Beilstein:2302110;   CAS:7448-02-4;   KEGG:C05108;   KNApSAcK:C00023776
 xref_mesh: MESH:C013499
 xref: Reaxys:2302110



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14-demethyllanosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Msmo1 methylsterol monooxygenase 1 decreases abundance ISO MSMO1 protein results in decreased abundance of 4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol CTD PMID:23125191 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      biological role 20011
        biochemical role 19671
          metabolite 19631
            eukaryotic metabolite 19358
              plant metabolite 17795
                lanosterol 7
                  14-demethyllanosterol 1
                    4beta-hydroxymethyl-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      carbon group element atom 19916
                        carbon atom 19909
                          organic molecular entity 19909
                            organic molecule 19856
                              organic cyclic compound 19612
                                organic polycyclic compound 17201
                                  steroid 14380
                                    hydroxy steroid 14111
                                      3-hydroxy steroid 12157
                                        sterol 447
                                          3beta-sterol 442
                                            lanosterol 7
                                              14-demethyllanosterol 1
                                                4beta-hydroxymethyl-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + 0
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