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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:14-demethyllanosterol
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Accession:CHEBI:18364 term browser browse the term
Definition:A 3beta-sterol formed formally by loss of a methyl group from the 14-position of lanosterol.
Synonyms:related_synonym: (3beta,5alpha)-4,4-dimethylcholesta-8,24-dien-3-ol;   14-desmethyllanosterol;   4,4-Dimethyl-5alpha-cholesta-8,24-dien-3beta-ol;   4,4-Dimethyl-8,24-cholestadienol;   4,4-dimethylcholesta-8(9),24-dien-3beta-ol;   4,4-dimethylzymosterol;   Formula=C29H48O;   InChI=1S/C29H48O/c1-19(2)9-8-10-20(3)22-12-13-23-21-11-14-25-27(4,5)26(30)16-18-29(25,7)24(21)15-17-28(22,23)6/h9,20,22-23,25-26,30H,8,10-18H2,1-7H3/t20-,22-,23+,25+,26+,28-,29-/m1/s1;   InChIKey=CHGIKSSZNBCNDW-QGBOJXOESA-N;   SMILES=C12=C([C@]3([C@]([C@](CC3)([C@@H](CCC=C(C)C)C)[H])(C)CC1)[H])CC[C@@]4([C@@]2(CC[C@@H](C4(C)C)O)C)[H]
 alt_id: CHEBI:11921;   CHEBI:19151;   CHEBI:755
 xref: CAS:7448-02-4;   KEGG:C05108;   KNApSAcK:C00023776
 xref_mesh: MESH:C013499
 xref: Reaxys:2302110


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14-demethyllanosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Msmo1 methylsterol monooxygenase 1 decreases abundance ISO MSMO1 protein results in decreased abundance of 4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol CTD PMID:23125191 NCBI chr16:29,747,113...29,764,360
Ensembl chr16:24,980,697...24,998,016 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19909
    role 19880
      biological role 19878
        biochemical role 19586
          metabolite 19573
            eukaryotic metabolite 19400
              plant metabolite 18035
                lanosterol 7
                  14-demethyllanosterol 1
                    4beta-hydroxymethyl-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19909
    subatomic particle 19907
      composite particle 19907
        hadron 19907
          baryon 19907
            nucleon 19907
              atomic nucleus 19907
                atom 19907
                  main group element atom 19846
                    p-block element atom 19846
                      carbon group element atom 19784
                        carbon atom 19781
                          organic molecular entity 19781
                            organic molecule 19735
                              organic cyclic compound 19528
                                organic polycyclic compound 17344
                                  steroid 15164
                                    hydroxy steroid 14987
                                      3-hydroxy steroid 13668
                                        sterol 472
                                          3beta-sterol 466
                                            lanosterol 7
                                              14-demethyllanosterol 1
                                                4beta-hydroxymethyl-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + 0
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