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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Lucidone
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Accession:CHEBI:183569 term browser browse the term
Synonyms:exact_synonym: 3-hydroxy-4-methoxy-2-[(E)-3-phenylprop-2-enoyl]cyclopenta-2,4-dien-1-one
 related_synonym: Formula=C15H12O4;   InChI=1S/C15H12O4/c1-19-13-9-12(17)14(15(13)18)11(16)8-7-10-5-3-2-4-6-10/h2-9,18H,1H3/b8-7+;   InChIKey=ANPTXNYQLGJVRE-BQYQJAHWSA-N;   SMILES=O(C=1C(O)=C(C(=O)C1)C(=O)/C=C/C2=CC=CC=C2)C
 xref: Chemspider:9428886;   LIPID_MAPS_instance:LMPK12120439
 xref_mesh: MESH:C529637



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Lucidone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO lucidone results in increased expression of HMOX1 protein
[lucidone co-treated with 2,2'-azobis(2-amidinopropane)] results in increased expression of HMOX1 protein; lucidone inhibits the reaction [Ethanol results in decreased expression of HMOX1 mRNA]; lucidone inhibits the reaction [Ethanol results in decreased expression of HMOX1 protein]
CTD PMID:22484158 PMID:23712098 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
affects response to substance
ISO [lucidone co-treated with 2,2'-azobis(2-amidinopropane)] affects the localization of and results in increased activity of NFE2L2 protein; [lucidone co-treated with Ethanol] results in increased expression of NFE2L2 mRNA; lucidone affects the localization of and results in increased activity of NFE2L2 protein; lucidone promotes the reaction [2,2'-azobis(2-amidinopropane) results in increased expression of NFE2L2 protein]
NFE2L2 protein affects the susceptibility to lucidone
CTD PMID:22484158 PMID:23712098 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO lucidone inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased degradation of NFKBIA protein] CTD PMID:23712098 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO lucidone inhibits the reaction [2,2'-azobis(2-amidinopropane) promotes the reaction [PTGS2 protein results in increased chemical synthesis of Dinoprostone]]; lucidone inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased expression of PTGS2 protein] CTD PMID:23712098 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO lucidone inhibits the reaction [2,2'-azobis(2-amidinopropane) affects the localization of RELA protein] CTD PMID:23712098 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO lucidone inhibits the reaction [Ethanol results in increased expression of TNF] CTD PMID:22484158 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20056
    chemical entity 20055
      atom 20054
        nonmetal atom 19945
          carbon atom 19875
            organic molecular entity 19875
              olefinic compound 16506
                Lucidone 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 20056
    subatomic particle 20054
      composite particle 20054
        hadron 20054
          baryon 20054
            nucleon 20054
              atomic nucleus 20054
                atom 20054
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19875
                          organic molecular entity 19875
                            organic group 18961
                              organic divalent group 18947
                                organodiyl group 18947
                                  carbonyl group 18900
                                    carbonyl compound 18900
                                      carboxylic acid 18594
                                        monocarboxylic acid 17840
                                          alpha,beta-unsaturated monocarboxylic acid 13218
                                            cinnamic acids 2435
                                              cinnamic acid 38
                                                Lucidone 6
paths to the root