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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:delta8-THC
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Accession:CHEBI:183415 term browser browse the term
Synonyms:exact_synonym: (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
 related_synonym: Formula=C21H30O2;   InChI=1S/C21H30O2/c1-5-6-7-8-15-12-18(22)20-16-11-14(2)9-10-17(16)21(3,4)23-19(20)13-15/h9,12-13,16-17,22H,5-8,10-11H2,1-4H3/t16-,17-/m1/s1;   InChIKey=HCAWPGARWVBULJ-IAGOWNOFSA-N;   SMILES=O1C([C@]2([C@@](CC(=CC2)C)(C=3C1=CC(=CC3O)CCCCC)[H])[H])(C)C
 xref: CAS:5957-75-5;   Chemspider:553592
 xref_mesh: MESH:C035731



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delta8-THC term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 increases metabolic processing
multiple interactions
ISO CYP2J2 protein results in increased metabolism of delta-8-tetrahydrocannabinol
delta-8-tetrahydrocannabinol inhibits the reaction [CYP2J2 protein results in increased metabolism of anandamide]
CTD PMID:29689453 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Gnb1 G protein subunit beta 1 affects binding ISO delta-8-tetrahydrocannabinol binds to GNB1 protein CTD PMID:29992186 NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124
JBrowse link
G Ifng interferon gamma multiple interactions ISO delta-8-tetrahydrocannabinol affects the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased secretion of TNF]; delta-8-tetrahydrocannabinol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased secretion of IL1B] CTD PMID:12813001 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO delta-8-tetrahydrocannabinol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased secretion of IL1B] CTD PMID:12813001 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Mtch2 mitochondrial carrier 2 affects binding ISO delta-8-tetrahydrocannabinol binds to MTCH2 protein CTD PMID:29992186 NCBI chr 3:76,830,549...76,850,189
Ensembl chr 3:76,830,413...76,850,189
JBrowse link
G Reep5 receptor accessory protein 5 affects binding ISO delta-8-tetrahydrocannabinol binds to REEP5 protein CTD PMID:29992186 NCBI chr18:25,945,375...25,983,271
Ensembl chr18:25,945,381...25,976,509
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO delta-8-tetrahydrocannabinol affects the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased secretion of TNF] CTD PMID:12813001 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    chemical entity 19840
      atom 19809
        nonmetal atom 19747
          oxygen atom 19520
            oxygen molecular entity 19490
              organooxygen compound 19137
                oxacycle 17819
                  benzopyran 11950
                    1-benzopyran 11702
                      delta8-THC 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    main group molecular entity 19759
                      p-block molecular entity 19759
                        carbon group molecular entity 19708
                          organic molecular entity 19705
                            organic molecule 19658
                              organic cyclic compound 19471
                                organic heterocyclic compound 18862
                                  organic heteropolycyclic compound 18301
                                    benzopyran 11950
                                      1-benzopyran 11702
                                        delta8-THC 7
paths to the root