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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(R)-goitrin
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Accession:CHEBI:183228 term browser browse the term
Definition:A 5-ethenyl-1,3-oxazolidine-2-thione that has R-configuration. It is a constituent of a traditional Chinese herbal medicine, Radix isatidis.
Synonyms:exact_synonym: (5R)-5-ethenyl-1,3-oxazolidine-2-thione
 related_synonym: (5R)-5-vinyl-1,3-oxazolidine-2-thione;   (R)-5-ethenyl-2-oxazolidinethione;   (R)-5-vinyl-2-oxazolidinethione;   BA 51-090278;   D-goitrin;   Formula=C5H7NOS;   InChI=1S/C5H7NOS/c1-2-4-3-6-5(8)7-4/h2,4H,1,3H2,(H,6,8)/t4-/m1/s1;   InChIKey=UZQVYLOFLQICCT-SCSAIBSYSA-N;   SMILES=[H][C@]1(CNC(=S)O1)C=C;   epigoitrin
 xref: CAS:1072-93-1;   Chemspider:2297322;   PMID:11170613;   PMID:17401984;   PMID:19160787;   PMID:23901642;   PMID:25345127;   PMID:26989425;   PMID:27022502;   PMID:27468553;   PMID:28617329;   PMID:28894621;   PMID:30505662;   PMID:30792656;   PMID:31918015;   PMID:32805551;   PMID:33755912;   PMID:34627086;   PMID:7390339
 cyclic_relationship: is_enantiomer_of CHEBI:80751


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(RS)-goitrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSTA2 glutathione S-transferase alpha 2 increases expression
multiple interactions		 ISO goitrin results in increased expression of GSTA2 protein
Triiodothyronine inhibits the reaction [goitrin results in increased expression of GSTA2 protein]		 CTD PMID:7532609 NCBI chr 6:52,750,087...52,763,475
Ensembl chr 6:52,750,087...52,763,475 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 increases expression
decreases expression
multiple interactions		 ISO goitrin results in increased expression of GSTP1 protein
goitrin results in decreased expression of GSTP1 protein
Triiodothyronine inhibits the reaction [goitrin results in increased expression of GSTP1 protein]		 CTD PMID:7532609 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26034
    role 25961
      biological role 25929
        antimicrobial agent 21890
          antiviral agent 11721
            (R)-goitrin 2
              (RS)-goitrin 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 26034
    subatomic particle 26009
      composite particle 26009
        hadron 26020
          baryon 26009
            nucleon 26009
              atomic nucleus 26009
                atom 26009
                  main group element atom 25834
                    p-block element atom 25834
                      carbon group element atom 25434
                        carbon atom 25403
                          organic molecular entity 25392
                            organic molecule 25222
                              organic cyclic compound 24274
                                organic heterocyclic compound 22328
                                  organic heteromonocyclic compound 19212
                                    oxazolidines 5275
                                      5-ethenyl-1,3-oxazolidine-2-thione 2
                                        (R)-goitrin 2
                                          (RS)-goitrin 2
paths to the root