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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:quinolin-2(1H)-one
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Accession:CHEBI:18289 term browser browse the term
Definition:A quinolone that is 1,2-dihydroquinoline substituted by an oxo group at position 2.
Synonyms:related_synonym: 2(1H)-Quinolinone;   2-quinolone;   Carbostyril;   Formula=C9H7NO;   InChI=1S/C9H7NO/c11-9-6-5-7-3-1-2-4-8(7)10-9/h1-6H,(H,10,11);   InChIKey=LISFMEBWQUVKPJ-UHFFFAOYSA-N;   SMILES=O=c1ccc2ccccc2[nH]1;   alpha-Quinolone;   o-Aminocinnamic acid lactam
 alt_id: CHEBI:15002;   CHEBI:26500;   CHEBI:44584;   CHEBI:850
 xref: CAS:59-31-4;   KEGG:C06415
 xref_mesh: MESH:C107724
 xref: PDBeChem:OCH;   PMID:23689721;   Reaxys:2855
 cyclic_relationship: is_tautomer_of CHEBI:16365


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quinolin-2(1H)-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pon1 paraoxonase 1 multiple interactions ISO 2-hydroxyquinoline inhibits the reaction [PON1 protein results in increased hydrolysis of Isoflurophate]; 2-hydroxyquinoline inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon] CTD PMID:21382471 NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22194
    chemical entity 22193
      molecular entity 22185
        polyatomic entity 22088
          molecule 21686
            organic molecule 21662
              organic cyclic compound 21269
                organic aromatic compound 20751
                  quinolines 2654
                    quinolone 333
                      quinolin-2(1H)-one 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 22194
    subatomic particle 22186
      composite particle 22186
        hadron 22186
          baryon 22186
            nucleon 22186
              atomic nucleus 22186
                atom 22186
                  main group element atom 22120
                    p-block element atom 22120
                      carbon group element atom 21920
                        carbon atom 21846
                          organic molecular entity 21846
                            organic molecule 21662
                              organic cyclic compound 21269
                                organic heterocyclic compound 20342
                                  organonitrogen heterocyclic compound 19086
                                    quinolines 2654
                                      quinolone 333
                                        quinolin-2(1H)-one 1
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