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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ornithine
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Accession:CHEBI:18257 term browser browse the term
Definition:An alpha-amino acid that is pentanoic acid bearing two amino substituents at positions 2 and 5.
Synonyms:related_synonym: 2,5-Diaminopentanoic acid;   2,5-Diaminovaleric acid;   DL-Ornithine;   Formula=C5H12N2O2;   InChI=1S/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9);   InChIKey=AHLPHDHHMVZTML-UHFFFAOYSA-N;   Orn;   SMILES=NCCCC(N)C(O)=O
 alt_id: CHEBI:7784
 xref: Beilstein:1722296;   CAS:616-07-9;   Gmelin:847696;   KEGG:C01602;   KNApSAcK:C00001384
 xref_mesh: MESH:D009952
 xref: PMID:15449570;   PMID:17190852;   PMID:22264337;   Reaxys:1722296
 cyclic_relationship: is_conjugate_acid_of CHEBI:32964;   is_conjugate_base_of CHEBI:46912


show annotations for term's descendants           Sort by:
ornithine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egf epidermal growth factor multiple interactions ISO [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Ornithine; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Ornithine] CTD PMID:22689575 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965 		JBrowse link
rhodotorulic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases activity		 ISO Calcium Chloride inhibits the reaction [rhodotorulic acid results in decreased activity of MMP2 protein]; ferric chloride inhibits the reaction [rhodotorulic acid results in decreased activity of MMP2 protein] CTD PMID:10086886 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048 		JBrowse link
S-methyl-L-thiocitrulline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 multiple interactions ISO S-methylthiocitrulline inhibits the reaction [EDN1 protein results in increased abundance of Nitric Oxide] CTD PMID:16380457 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466 		JBrowse link
G Nos1 nitric oxide synthase 1, neuronal multiple interactions
decreases activity		 ISO
EXP		 [S-methylthiocitrulline results in decreased activity of NOS1 protein] which affects the abundance of Sodium
[S-methylthiocitrulline results in decreased activity of NOS1 protein] which affects the susceptibility to Methamphetamine		 CTD PMID:11006970 PMID:12511180 NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905 		JBrowse link
G Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 multiple interactions ISO S-methylthiocitrulline inhibits the reaction [Methamphetamine results in decreased activity of SLC18A2 protein]; S-methylthiocitrulline inhibits the reaction [Methamphetamine results in decreased expression of SLC18A2 protein] CTD PMID:17683483 NCBI chr19:59,249,310...59,284,444
Ensembl chr19:59,249,328...59,284,444 		JBrowse link
sinefungin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt1 DNA methyltransferase 1 decreases activity ISO sinefungin results in decreased activity of DNMT1 protein CTD PMID:23671287 NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184 		JBrowse link
G Dnmt3a DNA methyltransferase 3A decreases activity EXP sinefungin results in decreased activity of DNMT3A protein CTD PMID:23671287 NCBI chr12:3,851,559...3,964,442
Ensembl chr12:3,856,007...3,964,443 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22194
    role 22179
      biological role 22178
        biochemical role 21449
          metabolite 21397
            eukaryotic metabolite 21256
              algal metabolite 16027
                ornithine 7
                  D-ornithine + 0
                  L-ornithine + 6
                  N(2)-ornithino group + 0
                  N(5)-ornithino group + 0
                  eflornithine + 0
                  ornithine derivative + 4
                  ornithine residue + 0
                  ornithyl group + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22194
    subatomic particle 22186
      composite particle 22186
        hadron 22186
          baryon 22186
            nucleon 22186
              atomic nucleus 22186
                atom 22186
                  main group element atom 22120
                    main group molecular entity 22120
                      s-block molecular entity 21717
                        hydrogen molecular entity 21634
                          hydrides 20777
                            inorganic hydride 18692
                              pnictogen hydride 18672
                                nitrogen hydride 18540
                                  azane 18447
                                    ammonia 18446
                                      organic amino compound 18446
                                        amino acid 16431
                                          non-proteinogenic amino acid 4035
                                            non-proteinogenic alpha-amino acid 3837
                                              ornithine 7
                                                D-ornithine + 0
                                                L-ornithine + 6
                                                N(2)-ornithino group + 0
                                                N(5)-ornithino group + 0
                                                eflornithine + 0
                                                ornithine derivative + 4
                                                ornithine residue + 0
                                                ornithyl group + 0
paths to the root