Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ornithine
go back to main search page
Accession:CHEBI:18257 term browser browse the term
Definition:An alpha-amino acid that is pentanoic acid bearing two amino substituents at positions 2 and 5.
Synonyms:related_synonym: 2,5-Diaminopentanoic acid;   2,5-Diaminovaleric acid;   DL-Ornithine;   Formula=C5H12N2O2;   InChI=1S/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9);   InChIKey=AHLPHDHHMVZTML-UHFFFAOYSA-N;   Orn;   SMILES=NCCCC(N)C(O)=O
 alt_id: CHEBI:7784
 xref: Beilstein:1722296;   CAS:616-07-9;   Gmelin:847696;   KEGG:C01602;   KNApSAcK:C00001384
 xref_mesh: MESH:D009952
 xref: PMID:15449570;   PMID:17190852;   PMID:22264337;   Reaxys:1722296
 cyclic_relationship: is_conjugate_acid_of CHEBI:32964;   is_conjugate_base_of CHEBI:46912


show annotations for term's descendants           Sort by:
 
ornithine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egf epidermal growth factor multiple interactions EXP [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Ornithine; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Ornithine] CTD PMID:22689575 NCBI chr 2:68,820,616...68,895,537 JBrowse link
rhodotorulic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases activity
ISO Calcium Chloride inhibits the reaction [rhodotorulic acid results in decreased activity of MMP2 protein]; ferric chloride inhibits the reaction [rhodotorulic acid results in decreased activity of MMP2 protein] CTD PMID:10086886 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
S-methyl-L-thiocitrulline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 multiple interactions EXP S-methylthiocitrulline inhibits the reaction [EDN1 protein results in increased abundance of Nitric Oxide] CTD PMID:16380457 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions
decreases activity
EXP
ISO
[S-methylthiocitrulline results in decreased activity of NOS1 protein] which affects the abundance of Sodium
[S-methylthiocitrulline results in decreased activity of NOS1 protein] which affects the susceptibility to Methamphetamine
CTD PMID:11006970, PMID:12511180 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions EXP S-methylthiocitrulline inhibits the reaction [Methamphetamine results in decreased activity of SLC18A2 protein]; S-methylthiocitrulline inhibits the reaction [Methamphetamine results in decreased expression of SLC18A2 protein] CTD PMID:17683483 NCBI chr 1:280,397,831...280,457,968
Ensembl chr 1:280,423,079...280,457,148
JBrowse link
sinefungin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt1 DNA methyltransferase 1 decreases activity ISO sinefungin results in decreased activity of DNMT1 protein CTD PMID:23671287 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases activity ISO sinefungin results in decreased activity of DNMT3A protein CTD PMID:23671287 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19792
    role 19738
      biological role 19737
        biochemical role 19241
          metabolite 19218
            eukaryotic metabolite 18842
              algal metabolite 13591
                ornithine 7
                  D-ornithine + 0
                  L-ornithine + 6
                  N(2)-ornithino group + 0
                  N(5)-ornithino group + 0
                  eflornithine + 0
                  ornithine derivative + 4
                  ornithine residue + 0
                  ornithyl group + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19792
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19675
                    p-block element atom 19675
                      carbon group element atom 19571
                        carbon atom 19560
                          organic molecular entity 19560
                            organic group 18508
                              organic divalent group 18501
                                organodiyl group 18501
                                  carbonyl group 18404
                                    carbonyl compound 18404
                                      carboxylic acid 18079
                                        amino acid 14080
                                          alpha-amino acid 11547
                                            non-proteinogenic alpha-amino acid 1542
                                              ornithine 7
                                                D-ornithine + 0
                                                L-ornithine + 6
                                                N(2)-ornithino group + 0
                                                N(5)-ornithino group + 0
                                                eflornithine + 0
                                                ornithine derivative + 4
                                                ornithine residue + 0
                                                ornithyl group + 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.