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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:zymosterol
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Accession:CHEBI:18252 term browser browse the term
Definition:A 3beta-sterol that has formula C27H44O.
Synonyms:related_synonym: 5alpha-Cholesta-8,24-dien-3beta-ol;   Formula=C27H44O;   InChI=1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,19-21,23-24,28H,6,8-17H2,1-5H3/t19-,20+,21+,23-,24+,26+,27-/m1/s1;   InChIKey=CGSJXLIKVBJVRY-XTGBIJOFSA-N;   SMILES=[H][C@@]12CCC3=C(CC[C@]4(C)[C@]([H])(CC[C@@]34[H])[C@H](C)CCC=C(C)C)[C@@]1(C)CC[C@H](O)C2;   delta8,24-Cholestadien-3beta-ol;   zymostrol
 alt_id: CHEBI:10131;   CHEBI:12172;   CHEBI:20646;   CHEBI:27370
 xref: Beilstein:2568614;   CAS:128-33-6;   KEGG:C05437;   KNApSAcK:C00023749;   LIPID_MAPS_instance:LMST01010066
 xref_mesh: MESH:C015582



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zymosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases metabolic processing ISO CYP27A1 protein results in increased metabolism of zymosterol CTD PMID:14622972 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Msmo1 methylsterol monooxygenase 1 decreases abundance ISO MSMO1 protein results in decreased abundance of zymosterol metabolite CTD PMID:23125191 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19860
    role 19832
      biological role 19830
        biochemical role 19538
          metabolite 19525
            eukaryotic metabolite 19347
              fungal metabolite 17956
                Saccharomyces cerevisiae metabolite 17472
                  zymosterol 2
                    26,27-dehydrozymosterol 0
                    3-dehydro-4-carboxyzymosterol 0
                    3-dehydro-4-methylzymosterol + 0
                    4-carboxy-4-methylzymosterol 0
                    4-carboxyzymosterol 0
                    4-formylzymosterol + 0
                    4-hydroxymethylzymosterol + 0
                    4-methylzymosterol 0
                    4alpha-hydroxymethyl-4beta-methylzymosterol 0
                    4alpha-methylzymosterol + 0
                    4beta-methylzymosterol-4-carbaldehyde 0
                    4beta-methylzymosterol-4alpha-carboxylic acid 0
                    zymosterol ester + 0
                    zymosterol intermediate 1c 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19860
    subatomic particle 19858
      composite particle 19858
        hadron 19858
          baryon 19858
            nucleon 19858
              atomic nucleus 19858
                atom 19858
                  main group element atom 19804
                    p-block element atom 19804
                      carbon group element atom 19745
                        carbon atom 19741
                          organic molecular entity 19741
                            organic molecule 19692
                              organic cyclic compound 19503
                                organic polycyclic compound 17267
                                  steroid 14721
                                    hydroxy steroid 14468
                                      3-hydroxy steroid 12813
                                        sterol 465
                                          3beta-sterol 459
                                            zymosterol 2
                                              26,27-dehydrozymosterol 0
                                              3-dehydro-4-carboxyzymosterol 0
                                              3-dehydro-4-methylzymosterol + 0
                                              4-carboxy-4-methylzymosterol 0
                                              4-carboxyzymosterol 0
                                              4-formylzymosterol + 0
                                              4-hydroxymethylzymosterol + 0
                                              4-methylzymosterol 0
                                              4alpha-hydroxymethyl-4beta-methylzymosterol 0
                                              4alpha-methylzymosterol + 0
                                              4beta-methylzymosterol-4-carbaldehyde 0
                                              4beta-methylzymosterol-4alpha-carboxylic acid 0
                                              zymosterol ester + 0
                                              zymosterol intermediate 1c 0
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