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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:zymosterol
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Accession:CHEBI:18252 term browser browse the term
Definition:A 3beta-sterol that has formula C27H44O.
Synonyms:related_synonym: 5alpha-Cholesta-8,24-dien-3beta-ol;   Formula=C27H44O;   InChI=1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,19-21,23-24,28H,6,8-17H2,1-5H3/t19-,20+,21+,23-,24+,26+,27-/m1/s1;   InChIKey=CGSJXLIKVBJVRY-XTGBIJOFSA-N;   SMILES=[H][C@@]12CCC3=C(CC[C@]4(C)[C@]([H])(CC[C@@]34[H])[C@H](C)CCC=C(C)C)[C@@]1(C)CC[C@H](O)C2;   delta8,24-Cholestadien-3beta-ol;   zymostrol
 alt_id: CHEBI:10131;   CHEBI:12172;   CHEBI:20646;   CHEBI:27370
 xref: Beilstein:2568614;   CAS:128-33-6;   KEGG:C05437;   KNApSAcK:C00023749;   LIPID_MAPS_instance:LMST01010066
 xref_mesh: MESH:C015582


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zymosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases metabolic processing ISO CYP27A1 protein results in increased metabolism of zymosterol CTD PMID:14622972 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Msmo1 methylsterol monooxygenase 1 decreases abundance ISO MSMO1 protein results in decreased abundance of zymosterol metabolite CTD PMID:23125191 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    role 19790
      biological role 19788
        biochemical role 19501
          metabolite 19486
            eukaryotic metabolite 19284
              fungal metabolite 17662
                Saccharomyces cerevisiae metabolite 16897
                  zymosterol 2
                    26,27-dehydrozymosterol 0
                    3-dehydro-4-carboxyzymosterol 0
                    3-dehydro-4-methylzymosterol + 0
                    4-carboxy-4-methylzymosterol 0
                    4-carboxyzymosterol 0
                    4-formylzymosterol + 0
                    4-hydroxymethylzymosterol + 0
                    4-methylzymosterol 0
                    4alpha-hydroxymethyl-4beta-methylzymosterol 0
                    4alpha-methylzymosterol + 0
                    4beta-methylzymosterol-4-carbaldehyde 0
                    4beta-methylzymosterol-4alpha-carboxylic acid 0
                    zymosterol ester + 0
                    zymosterol intermediate 1c 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    p-block element atom 19761
                      carbon group element atom 19703
                        carbon atom 19698
                          organic molecular entity 19698
                            organic molecule 19656
                              organic cyclic compound 19461
                                organic polycyclic compound 17202
                                  steroid 14409
                                    hydroxy steroid 14128
                                      3-hydroxy steroid 12206
                                        sterol 460
                                          3beta-sterol 454
                                            zymosterol 2
                                              26,27-dehydrozymosterol 0
                                              3-dehydro-4-carboxyzymosterol 0
                                              3-dehydro-4-methylzymosterol + 0
                                              4-carboxy-4-methylzymosterol 0
                                              4-carboxyzymosterol 0
                                              4-formylzymosterol + 0
                                              4-hydroxymethylzymosterol + 0
                                              4-methylzymosterol 0
                                              4alpha-hydroxymethyl-4beta-methylzymosterol 0
                                              4alpha-methylzymosterol + 0
                                              4beta-methylzymosterol-4-carbaldehyde 0
                                              4beta-methylzymosterol-4alpha-carboxylic acid 0
                                              zymosterol ester + 0
                                              zymosterol intermediate 1c 0
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