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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:zymosterol
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Accession:CHEBI:18252 term browser browse the term
Definition:A 3beta-sterol that has formula C27H44O.
Synonyms:related_synonym: 5alpha-Cholesta-8,24-dien-3beta-ol;   Formula=C27H44O;   InChI=1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,19-21,23-24,28H,6,8-17H2,1-5H3/t19-,20+,21+,23-,24+,26+,27-/m1/s1;   InChIKey=CGSJXLIKVBJVRY-XTGBIJOFSA-N;   SMILES=[H][C@@]12CCC3=C(CC[C@]4(C)[C@]([H])(CC[C@@]34[H])[C@H](C)CCC=C(C)C)[C@@]1(C)CC[C@H](O)C2;   delta8,24-Cholestadien-3beta-ol;   zymostrol
 alt_id: CHEBI:10131;   CHEBI:12172;   CHEBI:20646;   CHEBI:27370
 xref: Beilstein:2568614;   CAS:128-33-6;   KEGG:C05437;   KNApSAcK:C00023749;   LIPID_MAPS_instance:LMST01010066
 xref_mesh: MESH:C015582


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zymosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases metabolic processing ISO CYP27A1 protein results in increased metabolism of zymosterol CTD PMID:14622972 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Msmo1 methylsterol monooxygenase 1 decreases abundance ISO MSMO1 protein results in decreased abundance of zymosterol metabolite CTD PMID:23125191 NCBI chr16:26,859,441...26,875,880
Ensembl chr16:26,859,397...26,875,973
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      biological role 19764
        biochemical role 19313
          metabolite 19294
            eukaryotic metabolite 18943
              fungal metabolite 17421
                Saccharomyces cerevisiae metabolite 16485
                  zymosterol 2
                    26,27-dehydrozymosterol 0
                    3-dehydro-4-carboxyzymosterol 0
                    3-dehydro-4-methylzymosterol + 0
                    4-carboxy-4-methylzymosterol 0
                    4-carboxyzymosterol 0
                    4-formylzymosterol + 0
                    4-hydroxymethylzymosterol + 0
                    4-methylzymosterol 0
                    4alpha-hydroxymethyl-4beta-methylzymosterol 0
                    4alpha-methylzymosterol + 0
                    4beta-methylzymosterol-4-carbaldehyde 0
                    4beta-methylzymosterol-4alpha-carboxylic acid 0
                    zymosterol ester + 0
                    zymosterol intermediate 1c 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic molecule 19522
                              organic cyclic compound 19320
                                organic polycyclic compound 16395
                                  steroid 12800
                                    hydroxy steroid 12380
                                      3-hydroxy steroid 10008
                                        sterol 418
                                          3beta-sterol 412
                                            zymosterol 2
                                              26,27-dehydrozymosterol 0
                                              3-dehydro-4-carboxyzymosterol 0
                                              3-dehydro-4-methylzymosterol + 0
                                              4-carboxy-4-methylzymosterol 0
                                              4-carboxyzymosterol 0
                                              4-formylzymosterol + 0
                                              4-hydroxymethylzymosterol + 0
                                              4-methylzymosterol 0
                                              4alpha-hydroxymethyl-4beta-methylzymosterol 0
                                              4alpha-methylzymosterol + 0
                                              4beta-methylzymosterol-4-carbaldehyde 0
                                              4beta-methylzymosterol-4alpha-carboxylic acid 0
                                              zymosterol ester + 0
                                              zymosterol intermediate 1c 0
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