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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:zymosterol
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Accession:CHEBI:18252 term browser browse the term
Definition:A 3beta-sterol that has formula C27H44O.
Synonyms:related_synonym: 5alpha-Cholesta-8,24-dien-3beta-ol;   Formula=C27H44O;   InChI=1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,19-21,23-24,28H,6,8-17H2,1-5H3/t19-,20+,21+,23-,24+,26+,27-/m1/s1;   InChIKey=CGSJXLIKVBJVRY-XTGBIJOFSA-N;   SMILES=[H][C@@]12CCC3=C(CC[C@]4(C)[C@]([H])(CC[C@@]34[H])[C@H](C)CCC=C(C)C)[C@@]1(C)CC[C@H](O)C2;   delta8,24-Cholestadien-3beta-ol;   zymostrol
 alt_id: CHEBI:10131;   CHEBI:12172;   CHEBI:20646;   CHEBI:27370
 xref: Beilstein:2568614;   CAS:128-33-6;   KEGG:C05437;   KNApSAcK:C00023749;   LIPID_MAPS_instance:LMST01010066
 xref_mesh: MESH:C015582



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zymosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases metabolic processing ISO CYP27A1 protein results in increased metabolism of zymosterol CTD PMID:14622972 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Msmo1 methylsterol monooxygenase 1 decreases abundance ISO MSMO1 protein results in decreased abundance of zymosterol metabolite CTD PMID:23125191 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        biochemical role 19368
          metabolite 19344
            eukaryotic metabolite 19033
              fungal metabolite 17447
                Saccharomyces cerevisiae metabolite 16645
                  zymosterol 2
                    26,27-dehydrozymosterol 0
                    3-dehydro-4-carboxyzymosterol 0
                    3-dehydro-4-methylzymosterol + 0
                    4-carboxy-4-methylzymosterol 0
                    4-carboxyzymosterol 0
                    4-formylzymosterol + 0
                    4-hydroxymethylzymosterol + 0
                    4-methylzymosterol 0
                    4alpha-hydroxymethyl-4beta-methylzymosterol 0
                    4alpha-methylzymosterol + 0
                    4beta-methylzymosterol-4-carbaldehyde 0
                    4beta-methylzymosterol-4alpha-carboxylic acid 0
                    zymosterol ester + 0
                    zymosterol intermediate 1c 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic molecule 19549
                              organic cyclic compound 19343
                                organic polycyclic compound 16570
                                  steroid 13347
                                    hydroxy steroid 12976
                                      3-hydroxy steroid 10368
                                        sterol 438
                                          3beta-sterol 432
                                            zymosterol 2
                                              26,27-dehydrozymosterol 0
                                              3-dehydro-4-carboxyzymosterol 0
                                              3-dehydro-4-methylzymosterol + 0
                                              4-carboxy-4-methylzymosterol 0
                                              4-carboxyzymosterol 0
                                              4-formylzymosterol + 0
                                              4-hydroxymethylzymosterol + 0
                                              4-methylzymosterol 0
                                              4alpha-hydroxymethyl-4beta-methylzymosterol 0
                                              4alpha-methylzymosterol + 0
                                              4beta-methylzymosterol-4-carbaldehyde 0
                                              4beta-methylzymosterol-4alpha-carboxylic acid 0
                                              zymosterol ester + 0
                                              zymosterol intermediate 1c 0
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