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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:iron atom
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Accession:CHEBI:18248 term browser browse the term
Definition:An iron group element atom that has atomic number 26.
Synonyms:related_synonym: 26Fe;   Eisen;   Fe;   Formula=Fe;   InChI=1S/Fe;   InChIKey=XEEYBQQBJWHFJM-UHFFFAOYSA-N;   SMILES=[Fe];   fer;   ferrum;   hierro;   iron
 alt_id: CHEBI:13322;   CHEBI:24872;   CHEBI:5974
 xref: CAS:7439-89-6;   DrugBank:DB01592;   HMDB:HMDB0015531;   KEGG:C00023
 xref_mesh: MESH:D007501
 xref: Reaxys:4122945;   WebElements:Fe



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iron atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO ABCC1 protein promotes the reaction [Nitric Oxide results in increased secretion of Iron] CTD PMID:16679408 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 affects metabolic processing ISO ABCG2 protein affects the metabolism of Iron CTD PMID:17194590 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Acbd3 acyl-CoA binding domain containing 3 multiple interactions EXP Nitric Oxide promotes the reaction [[RASD1 protein binds to ACBD3 protein binds to SLC11A2 protein] which results in increased uptake of Iron] CTD PMID:16908409 NCBI chr13:92,455,813...92,484,556
Ensembl chr13:92,455,655...92,483,380
JBrowse link
G Aco1 aconitase 1 multiple interactions
affects metabolic processing
ISO
EXP
Iron inhibits the reaction [nickel chloride results in increased activity of ACO1 protein]; Iron inhibits the reaction [Nickel results in increased activity of ACO1 protein]
[Deferoxamine results in decreased abundance of Iron] which results in increased activity of ACO1 protein
ACO1 protein affects the metabolism of Iron
CTD PMID:15893546 PMID:16039939 PMID:16877034 PMID:17194590 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Aco2 aconitase 2 multiple interactions
increases activity
EXP [[[Superoxides results in decreased activity of ACO2 protein] which results in increased abundance of Iron] which co-treated with Hydrogen Peroxide] results in increased chemical synthesis of Hydroxyl Radical; [Superoxides results in decreased activity of ACO2 protein] which results in increased abundance of Iron; ACO2 protein affects the reaction [Paraquat results in increased abundance of Iron]; Iron deficiency promotes the reaction [Clofibrate results in increased expression of ACO2 protein]; Iron inhibits the reaction [manganese chloride results in decreased activity of ACO2 protein]; Iron inhibits the reaction [Manganese results in decreased activity of ACO2 protein]
Iron results in increased activity of ACO2 protein
CTD PMID:9675333 PMID:11969379 PMID:16162655 PMID:21517855 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Acsf2 acyl-CoA synthetase family member 2 decreases expression EXP Iron deficiency results in decreased expression of ACSF2 mRNA CTD PMID:16629162 NCBI chr10:79,504,510...79,546,714
Ensembl chr10:79,504,511...79,546,673
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression EXP Iron deficiency results in decreased expression of ACSL1 mRNA CTD PMID:19821111 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression EXP Iron deficiency results in decreased expression of ACSL3 mRNA CTD PMID:19821111 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 decreases expression ISO Iron deficiency results in decreased expression of ADGRG1 mRNA CTD PMID:20368581 NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108
JBrowse link
G Ahsp alpha hemoglobin stabilizing protein multiple interactions ISO AHSP protein binds to and affects the folding of and affects the stability of [HBA1 protein binds to Iron] CTD PMID:16901899 NCBI chr 1:182,879,901...182,885,508
Ensembl chr 1:182,880,076...182,885,506
JBrowse link
G Akap13 A-kinase anchoring protein 13 decreases expression EXP Iron deficiency results in decreased expression of AKAP13 mRNA CTD PMID:16629162 NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation
EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Iron results in increased phosphorylation of AKT1 protein]; [Iron-Dextran Complex results in increased abundance of Iron] which results in decreased phosphorylation of AKT1 protein; Deferiprone inhibits the reaction [Iron results in increased phosphorylation of AKT1 protein]; Ergothioneine inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in decreased phosphorylation of AKT1 protein]; Filipin inhibits the reaction [Iron results in increased phosphorylation of AKT1 protein]; HRAS protein affects the reaction [Iron results in increased phosphorylation of AKT1 protein]; MAP3K7 protein affects the reaction [Iron results in increased phosphorylation of AKT1 protein]; PIK3R1 protein affects the reaction [Iron results in increased phosphorylation of AKT1 protein]; taxifolin inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in decreased phosphorylation of AKT1 protein] CTD PMID:17172471 PMID:32828744 PMID:33580994 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alas2 5'-aminolevulinate synthase 2 increases expression ISO Iron results in increased expression of ALAS2 mRNA CTD PMID:16424395 NCBI chr  X:19,463,146...19,486,526
Ensembl chr  X:19,463,171...19,486,519
JBrowse link
G Alb albumin multiple interactions ISO ALB protein affects the reaction [[Iron co-treated with Bicarbonates] results in increased abundance of Malondialdehyde]; ALB protein inhibits the reaction [[Iron co-treated with Phosphates] results in increased abundance of Malondialdehyde] CTD PMID:16027354 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C decreases expression ISO Iron deficiency results in decreased expression of ALDOC mRNA CTD PMID:20368581 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
JBrowse link
G Ankrd22 ankyrin repeat domain 22 increases expression ISO Iron deficiency results in increased expression of ANKRD22 mRNA CTD PMID:20368581 NCBI chr 1:231,639,035...231,670,537
Ensembl chr 1:231,639,314...231,670,381
JBrowse link
G Ankrd37 ankyrin repeat domain 37 increases expression EXP
ISO
Iron deficiency results in increased expression of ANKRD37 mRNA CTD PMID:16629162 PMID:23776592 NCBI chr16:46,269,025...46,271,971
Ensembl chr16:46,268,443...46,271,963
JBrowse link
G Anxa1 annexin A1 decreases expression EXP Iron deficiency results in decreased expression of ANXA1 mRNA CTD PMID:19821111 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Anxa2 annexin A2 increases expression ISO Iron deficiency results in increased expression of ANXA2 mRNA CTD PMID:20368581 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Ap1s3 adaptor related protein complex 1 subunit sigma 3 decreases expression ISO Iron deficiency results in decreased expression of AP1S3 mRNA CTD PMID:20368581 NCBI chr 9:80,950,402...81,039,685
Ensembl chr 9:80,950,715...81,009,798
JBrowse link
G Ap2a1 adaptor related protein complex 2 subunit alpha 1 multiple interactions EXP [Tungsten co-treated with Nickel co-treated with Iron] results in decreased expression of AP2A1 mRNA CTD PMID:24619124 NCBI chr 1:95,384,303...95,414,249
Ensembl chr 1:95,384,309...95,414,147
JBrowse link
G Apoe apolipoprotein E increases response to substance ISO APOE gene polymorphism results in increased susceptibility to Iron CTD PMID:15993987 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Apoh apolipoprotein H decreases expression EXP Iron deficiency results in decreased expression of APOH mRNA CTD PMID:19821111 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329
JBrowse link
G App amyloid beta precursor protein increases uptake
increases expression
ISO Iron results in increased uptake of APP protein
Iron results in increased expression of APP mRNA
CTD PMID:15993987 PMID:16308480 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Aqp4 aquaporin 4 increases expression
multiple interactions
EXP
ISO
Iron deficiency results in increased expression of AQP4 mRNA
[ferrous chloride results in increased abundance of Iron] which results in increased expression of AQP4 mRNA; [ferrous chloride results in increased abundance of Iron] which results in increased expression of AQP4 protein; SB 203580 inhibits the reaction [[ferrous chloride results in increased abundance of Iron] which results in increased expression of AQP4 protein]; U 0126 inhibits the reaction [[ferrous chloride results in increased abundance of Iron] which results in increased expression of AQP4 protein]; Vitamin E inhibits the reaction [[ferrous chloride results in increased abundance of Iron] which results in increased expression of AQP4 protein]
CTD PMID:16629162 PMID:30914277 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
JBrowse link
G Arid3b AT-rich interaction domain 3B increases expression ISO Iron deficiency results in increased expression of ARID3B mRNA CTD PMID:20368581 NCBI chr 8:58,193,268...58,240,901
Ensembl chr 8:58,193,418...58,238,318
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO ARNT protein affects the reaction [Iron deficiency results in increased activity of CP promoter] CTD PMID:10777486 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
JBrowse link
G Arrdc3 arrestin domain containing 3 increases expression ISO Iron deficiency results in increased expression of ARRDC3 mRNA CTD PMID:20368581 NCBI chr 2:11,137,443...11,149,978
Ensembl chr 2:11,137,460...11,149,978
JBrowse link
G Atm ATM serine/threonine kinase affects response to substance
affects abundance
multiple interactions
ISO ATM protein affects the susceptibility to Iron
ATM protein affects the abundance of Iron
Iron results in increased phosphorylation of and results in increased activity of ATM protein
CTD PMID:15336622 PMID:16959548 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atp7a ATPase copper transporting alpha affects metabolic processing
increases expression
multiple interactions
affects transport
decreases oxidation
increases response to substance
ISO
EXP
ATP7A protein mutant form affects the metabolism of Iron
Iron deficiency results in increased expression of ATP7A; Iron deficiency results in increased expression of ATP7A mRNA; Iron deficiency results in increased expression of ATP7A protein
[Iron deficiency results in increased expression of ATP7A] which results in increased abundance of Copper
ATP7A mutant form affects the transport of Iron
ATP7A gene mutant form results in decreased oxidation of Iron
ATP7A gene mutant form results in increased susceptibility to Iron deficiency
[ATP7A gene mutant form co-treated with Iron deficiency] results in increased uptake of Copper; [ATP7A gene mutant form co-treated with Iron deficiency] results in increased uptake of Iron; ATP7A gene mutant form promotes the reaction [Iron deficiency results in increased expression of MT1 mRNA]; Iron deficiency inhibits the reaction [ATP7A gene mutant form results in decreased oxidation of Iron]
CTD PMID:16629162 PMID:21852364 PMID:23174565 PMID:23776592 PMID:23814049 More... NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Atp7b ATPase copper transporting beta increases abundance EXP ATP7B gene mutant form results in increased abundance of Iron CTD PMID:15911138 NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
JBrowse link
G B2m beta-2 microglobulin multiple interactions
affects metabolic processing
ISO [HFE protein binds to B2M protein binds to SLC11A2 protein] which results in decreased uptake of Iron
B2M protein affects the metabolism of Iron
CTD PMID:16841247 PMID:17194590 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO [Arachidonic Acid co-treated with Iron] results in increased expression of BAD protein; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased expression of BAD protein] CTD PMID:30626086 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of BAX protein]; [Arachidonic Acid co-treated with Iron] results in increased expression of BAX protein; [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of BAX protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of BAX protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of BAX protein]; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased expression of BAX protein]; SB 203580 inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of BAX protein] CTD PMID:30626086 PMID:33285147 PMID:33393188 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl10 BCL10, immune signaling adaptor multiple interactions ISO [Arsenic co-treated with Iron] results in increased expression of BCL10 mRNA CTD PMID:31739468 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Arachidonic Acid co-treated with Iron] results in decreased expression of BCL2 protein; [Iron-Dextran Complex results in increased abundance of Iron] which results in decreased expression of BCL2 protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in decreased expression of BCL2 protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in decreased expression of BCL2 protein]; Resveratrol inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in decreased expression of BCL2 protein] CTD PMID:19620254 PMID:33285147 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO [Arachidonic Acid co-treated with Iron] results in decreased expression of BCL2L1 protein; Drugs, Chinese Herbal inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in decreased expression of BCL2L1 protein]; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in decreased expression of BCL2L1 protein]; Resveratrol inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in decreased expression of BCL2L1 protein] CTD PMID:19620254 PMID:27916511 PMID:30626086 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl3 BCL3, transcription coactivator increases expression ISO Iron deficiency results in increased expression of BCL3 mRNA CTD PMID:20368581 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
JBrowse link
G Bmp6 bone morphogenetic protein 6 decreases abundance
increases expression
decreases expression
increases abundance
ISO
EXP
BMP6 protein results in decreased abundance of Iron
Iron results in increased expression of BMP6 mRNA
Iron deficiency results in decreased expression of BMP6 mRNA
BMP6 gene mutant form results in increased abundance of Iron
CTD PMID:19252486 PMID:19252488 PMID:20164366 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression ISO Iron deficiency results in increased expression of BNIP3 mRNA CTD PMID:23776592 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C multiple interactions ISO [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of CACNA1C protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of CACNA1C protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of CACNA1C protein] CTD PMID:33285147 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
JBrowse link
G Calr calreticulin increases expression ISO Iron results in increased expression of CALR mRNA; Iron results in increased expression of CALR protein CTD PMID:11500943 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta multiple interactions ISO [Arsenic co-treated with Iron] results in increased expression of CAMK2D mRNA CTD PMID:31739468 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178
JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of and results in increased cleavage of CASP3 protein]; [Acetaminophen co-treated with [ferric nitrate results in increased abundance of Iron]] results in increased cleavage of CASP3 protein; [Arachidonic Acid co-treated with Iron] results in decreased expression of CASP3 protein; [Arachidonic Acid co-treated with Iron] results in increased cleavage of CASP3 protein; [Arachidonic Acid co-treated with Iron] results in increased expression of CASP3 protein modified form; [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of and results in increased cleavage of CASP3 protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of and results in increased cleavage of CASP3 protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of and results in increased cleavage of CASP3 protein]; Drugs, Chinese Herbal inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased cleavage of CASP3 protein]; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased cleavage of CASP3 protein]; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased expression of CASP3 protein modified form]; Resveratrol inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in decreased expression of CASP3 protein]; Rifampin inhibits the reaction [[Acetaminophen co-treated with [ferric nitrate results in increased abundance of Iron]] results in increased cleavage of CASP3 protein]; SB 203580 inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of and results in increased cleavage of CASP3 protein]; U 0126 inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of and results in increased cleavage of CASP3 protein]
[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of CASP3 protein
[Iron-Dextran Complex results in increased abundance of Iron] which results in increased activity of CASP3 protein; Ergothioneine inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased activity of CASP3 protein]; taxifolin inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased activity of CASP3 protein]
CTD PMID:19620254 PMID:27916511 PMID:30626086 PMID:31678598 PMID:32828744 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase multiple interactions
decreases activity
ISO
EXP
Iron deficiency inhibits the reaction [Benzoyl Peroxide results in decreased activity of CAT protein]; Iron promotes the reaction [Benzoyl Peroxide results in decreased activity of CAT protein]; Iron promotes the reaction [cumene hydroperoxide results in decreased activity of CAT protein]; Iron promotes the reaction [Hydrogen Peroxide results in decreased activity of CAT protein]; Iron promotes the reaction [mezerein results in decreased activity of CAT protein]; Iron promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]
[Arsenic co-treated with Cadmium co-treated with Lead co-treated with Mercury co-treated with Chromium co-treated with Nickel co-treated with Manganese co-treated with Iron] results in decreased activity of CAT protein; [Iron-Dextran Complex results in increased abundance of Iron] which results in decreased activity of CAT protein; [Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of CAT protein]; Ergothioneine inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in decreased activity of CAT protein]
Iron results in decreased activity of CAT protein
CTD PMID:12065085 PMID:12067571 PMID:12504893 PMID:17176674 PMID:22534743 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav1 caveolin 1 affects localization EXP Iron affects the localization of CAV1 protein CTD PMID:17172471 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
multiple interactions
ISO
EXP
Iron deficiency results in increased expression of CCL2 mRNA
[Iron co-treated with Diethylnitrosamine] results in increased expression of CCL2 mRNA; Iron promotes the reaction [[Copper co-treated with Diethylnitrosamine] results in increased expression of CCL2 mRNA]
CTD PMID:20302851 PMID:20368581 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions EXP [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of CCL3 mRNA CTD PMID:22198552 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO Iron deficiency results in increased expression of CCL5 mRNA CTD PMID:20368581 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccna2 cyclin A2 multiple interactions ISO [Arsenic co-treated with Iron] results in decreased expression of CCNA2 mRNA CTD PMID:31739468 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnd1 cyclin D1 increases expression EXP
ISO
Iron deficiency results in increased expression of CCND1 mRNA; Iron results in increased expression of CCND1; Iron results in increased expression of CCND1 mRNA; Iron results in increased expression of CCND1 protein CTD PMID:16629162 PMID:16890145 PMID:22649188 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccng2 cyclin G2 increases expression ISO Iron deficiency results in increased expression of CCNG2 mRNA CTD PMID:20368581 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
JBrowse link
G Ccpg1 cell cycle progression 1 increases expression ISO Iron deficiency results in increased expression of CCPG1 mRNA CTD PMID:20368581 NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430
JBrowse link
G Ccsap centriole, cilia and spindle-associated protein increases expression ISO Iron deficiency results in increased expression of CCSAP mRNA CTD PMID:20368581 NCBI chr19:51,824,954...51,843,469
Ensembl chr19:51,826,994...51,842,753
JBrowse link
G Cd109 CD109 molecule increases expression ISO Iron deficiency results in increased expression of CD109 mRNA CTD PMID:20368581 NCBI chr 8:79,454,480...79,569,195
Ensembl chr 8:79,454,480...79,569,194
JBrowse link
G Cd14 CD14 molecule multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [Iron deficiency results in increased expression of CD14 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Iron deficiency results in increased expression of CD14 protein]; Vitamin D promotes the reaction [Iron deficiency results in increased expression of CD14 protein] CTD PMID:20368581 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd1d1 CD1d1 molecule decreases expression EXP Iron deficiency results in decreased expression of CD1D1 mRNA CTD PMID:19821111 NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089
JBrowse link
G Cd300a Cd300a molecule increases expression ISO Iron deficiency results in increased expression of CD300A mRNA CTD PMID:20368581 NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674
JBrowse link
G Cd36 CD36 molecule decreases expression EXP Iron deficiency results in decreased expression of CD36 mRNA CTD PMID:16629162 PMID:19821111 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cd70 Cd70 molecule increases expression ISO Iron deficiency results in increased expression of CD70 mRNA CTD PMID:20368581 NCBI chr 9:2,006,563...2,009,715
Ensembl chr 9:2,006,563...2,009,715
JBrowse link
G Cd74 CD74 molecule decreases expression ISO Iron deficiency results in decreased expression of CD74 mRNA CTD PMID:20368581 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase decreases expression EXP Iron deficiency results in decreased expression of CDIPT mRNA CTD PMID:19821111 NCBI chr 1:181,583,098...181,587,409
Ensembl chr 1:181,583,141...181,587,408
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions EXP [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of CDKN1A mRNA CTD PMID:22198552 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression EXP Iron deficiency results in decreased expression of CDKN1C mRNA CTD PMID:16629162 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D increases expression ISO Iron deficiency results in increased expression of CDKN2D mRNA CTD PMID:20368581 NCBI chr 8:19,831,874...19,834,640
Ensembl chr 8:19,831,866...19,834,674
JBrowse link
G Cdo1 cysteine dioxygenase type 1 multiple interactions EXP Iron binds to and results in increased activity of CDO1 protein CTD PMID:16611640 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
JBrowse link
G Cdrt4 CMT1A duplicated region transcript 4 increases expression ISO Iron deficiency results in increased expression of CDRT4 mRNA CTD PMID:20368581 NCBI chr10:47,625,448...47,657,493
Ensembl chr10:47,625,470...47,657,493
JBrowse link
G Cds1 CDP-diacylglycerol synthase 1 decreases expression EXP Iron deficiency results in decreased expression of CDS1 mRNA CTD PMID:19821111 NCBI chr14:7,820,328...7,882,943
Ensembl chr14:7,820,351...7,882,681
JBrowse link
G Cel carboxyl ester lipase increases expression EXP Iron deficiency results in increased expression of CEL mRNA CTD PMID:19821111 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035
JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions EXP [Nickel co-treated with Iron co-treated with Tungsten] results in decreased expression of CHEK2 mRNA CTD PMID:22198552 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Chi3l1 chitinase 3 like 1 decreases expression ISO Iron deficiency results in decreased expression of CHI3L1 mRNA CTD PMID:20368581 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
JBrowse link
G Chrnd cholinergic receptor nicotinic delta subunit multiple interactions EXP [Tungsten co-treated with Nickel co-treated with Iron] results in decreased expression of CHRND mRNA CTD PMID:24619124 NCBI chr 9:87,862,417...87,870,833
Ensembl chr 9:87,862,407...87,870,833
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions EXP
ISO
deferiprone inhibits the reaction [Iron results in increased activity of [CHUK protein binds to IKBKB protein]]; Filipin inhibits the reaction [Iron results in increased activity of [CHUK protein binds to IKBKB protein]]; Iron results in increased activity of [CHUK protein binds to IKBKB protein]; N,N'-bis(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid inhibits the reaction [Iron results in increased activity of [CHUK protein binds to IKBKB protein]]
[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of CHUK protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of CHUK protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of CHUK protein]
CTD PMID:17172471 PMID:33285147 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Cldn2 claudin 2 increases expression EXP Iron deficiency results in increased expression of CLDN2 mRNA CTD PMID:16629162 NCBI chr  X:103,459,870...103,473,794
Ensembl chr  X:103,459,780...103,474,838
JBrowse link
G Clps colipase increases expression EXP Iron deficiency results in increased expression of CLPS mRNA CTD PMID:19821111 NCBI chr20:6,620,529...6,622,709
Ensembl chr20:6,620,529...6,622,689
JBrowse link
G Cnn3 calponin 3 increases expression EXP Iron deficiency results in increased expression of CNN3 mRNA CTD PMID:16629162 NCBI chr 2:209,518,948...209,550,107
Ensembl chr 2:209,518,948...209,550,104
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP Iron promotes the reaction [Asbestos, Amosite results in increased expression of COL1A1 mRNA] CTD PMID:11306436 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Cp ceruloplasmin increases abundance
multiple interactions
increases activity
increases oxidation
increases expression
decreases export
affects binding
ISO
EXP
CP gene mutant form results in increased abundance of Iron
[Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of CP protein]
Iron deficiency results in increased activity of CP promoter
CP protein results in increased oxidation of Iron
Iron deficiency results in increased expression of CP protein; Iron deficiency results in increased expression of CP protein modified form
CP gene mutant form results in decreased export of Iron
CP protein binds to [TF protein binds to Iron]
[CP protein results in increased oxidation of Iron] which results in increased stability of SLC40A1 protein; ARNT protein affects the reaction [Iron deficiency results in increased activity of CP promoter]
[CP gene mutant form results in increased abundance of Iron] which results in decreased expression of TFRC mRNA; [CP gene mutant form results in increased abundance of Iron] which results in increased expression of FTH1 mRNA; [CP gene mutant form results in increased abundance of Iron] which results in increased expression of FTL mRNA; [CP gene mutant form results in increased abundance of Iron] which results in increased expression of SLC11A1 mRNA; Iron inhibits the reaction [Diethylnitrosamine results in increased expression of CP protein]
CTD PMID:10777486 PMID:12572680 PMID:16988052 PMID:19061943 PMID:20655381 More... NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions EXP [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of CSF2 mRNA CTD PMID:22198552 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Cstf2t cleavage stimulation factor subunit 2, tau variant decreases expression ISO Iron deficiency results in decreased expression of CSTF2T mRNA CTD PMID:20368581 NCBI chr 1:228,952,617...228,956,183
Ensembl chr 1:228,952,504...228,955,873
JBrowse link
G Ctnnbip1 catenin, beta-interacting protein 1 decreases expression EXP Iron deficiency results in decreased expression of CTNNBIP1 mRNA CTD PMID:19821111 NCBI chr 5:159,961,961...160,010,942
Ensembl chr 5:159,961,928...160,010,939
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions EXP [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of CXCL1 protein CTD PMID:22198552 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions EXP [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of CXCL2 protein CTD PMID:22198552 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cybrd1 cytochrome b reductase 1 decreases expression
increases expression
ISO
EXP
Iron results in decreased expression of CYBRD1 protein
Iron deficiency results in increased expression of CYBRD1 mRNA
Iron results in increased expression of CYBRD1 protein
CTD PMID:16629162 PMID:18815723 PMID:19821111 PMID:21540277 PMID:23776592 More... NCBI chr 3:55,934,874...55,962,132
Ensembl chr 3:55,934,874...55,962,108
JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 decreases expression EXP Iron deficiency results in decreased expression of CYP2B15 mRNA CTD PMID:16629162 NCBI chr 1:82,094,188...82,106,492
Ensembl chr 1:82,094,180...82,106,492
JBrowse link
G Cytip cytohesin 1 interacting protein increases expression ISO Iron deficiency results in increased expression of CYTIP mRNA CTD PMID:20368581 NCBI chr 3:42,698,058...42,774,955
Ensembl chr 3:42,698,768...42,725,993
JBrowse link
G Dapl1 death associated protein-like 1 decreases expression EXP Iron deficiency results in decreased expression of DAPL1 mRNA CTD PMID:16629162 NCBI chr 3:43,960,993...43,980,940
Ensembl chr 3:43,960,810...43,980,940
JBrowse link
G Daxx death-domain associated protein increases expression ISO Iron results in increased expression of DAXX mRNA CTD PMID:16308480 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO
EXP
Iron deficiency results in increased expression of DDIT3 mRNA
[Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of DDIT3 mRNA
CTD PMID:20368581 PMID:22198552 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Defa6 defensin alpha 6 increases expression EXP Iron deficiency results in increased expression of DEFA6 mRNA CTD PMID:16629162 NCBI chr16:70,405,268...70,406,142
Ensembl chr16:70,405,268...70,406,142
JBrowse link
G Dgka diacylglycerol kinase, alpha increases expression EXP Iron deficiency results in increased expression of DGKA mRNA CTD PMID:19821111 NCBI chr 7:1,148,734...1,175,324
Ensembl chr 7:1,148,735...1,175,110
JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein increases expression EXP Iron deficiency results in increased expression of DLC1 mRNA CTD PMID:16629162 NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439
JBrowse link
G Dock10 dedicator of cytokinesis 10 increases expression ISO Iron deficiency results in increased expression of DOCK10 mRNA CTD PMID:20368581 NCBI chr 9:81,843,599...82,101,540
Ensembl chr 9:81,843,604...82,101,525
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions EXP [manganese chloride co-treated with Iron deficiency] results in decreased expression of DRD1 protein CTD PMID:22479410 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions EXP [manganese chloride co-treated with Iron deficiency] results in increased expression of DRD2 protein CTD PMID:22479410 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions EXP [Nickel co-treated with Iron co-treated with Tungsten] results in decreased expression of E2F1 mRNA CTD PMID:22198552 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G E2f8 E2F transcription factor 8 increases expression ISO Iron deficiency results in increased expression of E2F8 mRNA CTD PMID:20368581 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098
JBrowse link
G Edn1 endothelin 1 multiple interactions EXP [Iron co-treated with Diethylnitrosamine] results in increased expression of EDN1 protein; Copper promotes the reaction [[Iron co-treated with Diethylnitrosamine] results in increased expression of EDN1 protein] CTD PMID:20302851 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase increases expression EXP Iron deficiency results in increased expression of EEF2K mRNA CTD PMID:16629162 NCBI chr 1:175,393,119...175,454,452
Ensembl chr 1:175,393,154...175,455,164
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO [Arsenic co-treated with Iron] results in decreased expression of EGFR mRNA CTD PMID:31739468 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 affects binding ISO Iron binds to EGLN1 protein CTD PMID:16649251 NCBI chr19:52,867,914...52,907,169
Ensembl chr19:52,869,486...52,907,777
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 increases expression EXP Iron deficiency results in increased expression of EGLN3 mRNA CTD PMID:16629162 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
JBrowse link
G Egr1 early growth response 1 increases expression
multiple interactions
EXP Iron deficiency results in increased expression of EGR1 mRNA
[Tungsten co-treated with Nickel co-treated with Iron] results in increased expression of EGR1 mRNA
CTD PMID:16629162 PMID:24619124 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Elane elastase, neutrophil expressed decreases expression ISO Iron deficiency results in decreased expression of ELANE mRNA CTD PMID:20368581 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100
JBrowse link
G Emp1 epithelial membrane protein 1 increases expression ISO Iron deficiency results in increased expression of EMP1 mRNA CTD PMID:20368581 NCBI chr 4:168,212,901...168,233,039
Ensembl chr 4:168,212,861...168,232,904
JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions
increases expression
ISO
EXP
Iron inhibits the reaction [galangin results in increased expression of EPAS1 protein]; Iron inhibits the reaction [Quercetin results in increased expression of EPAS1 protein]
Iron deficiency results in increased expression of EPAS1 protein
CTD PMID:17973296 PMID:23814049 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Epo erythropoietin affects response to substance ISO Iron affects the susceptibility to EPO protein CTD PMID:24806658 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Exoc6 exocyst complex component 6 affects metabolic processing ISO EXOC6 protein affects the metabolism of Iron CTD PMID:17194590 NCBI chr 1:235,314,612...235,457,824
Ensembl chr 1:235,300,369...235,457,015
JBrowse link
G F13a1 coagulation factor XIII A1 chain decreases expression ISO Iron deficiency results in decreased expression of F13A1 mRNA CTD PMID:20368581 NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700
JBrowse link
G F2 coagulation factor II decreases activity ISO Iron results in decreased activity of F2 protein CTD PMID:6421970 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G Fabp2 fatty acid binding protein 2 increases expression EXP Iron deficiency results in increased expression of FABP2 mRNA CTD PMID:19821111 NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089
JBrowse link
G Fabp6 fatty acid binding protein 6 increases expression EXP Iron deficiency results in increased expression of FABP6 mRNA CTD PMID:19821111 NCBI chr10:28,063,603...28,068,276
Ensembl chr10:28,063,603...28,068,282
JBrowse link
G Fam117b family with sequence similarity 117, member B increases expression EXP Iron deficiency results in increased expression of FAM117B mRNA CTD PMID:16629162 NCBI chr 9:61,340,291...61,418,531
Ensembl chr 9:61,340,249...61,408,483
JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase decreases expression ISO Iron deficiency results in decreased expression of FAM20C mRNA CTD PMID:20368581 NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543
JBrowse link
G Fbxw5 F-box and WD repeat domain containing 5 multiple interactions EXP [Tungsten co-treated with Nickel co-treated with Iron] results in decreased expression of FBXW5 mRNA CTD PMID:24619124 NCBI chr 3:8,322,543...8,327,092
Ensembl chr 3:8,322,543...8,327,092
JBrowse link
G Fech ferrochelatase multiple interactions ISO [Aminolevulinic Acid results in decreased activity of FECH protein] which results in increased abundance of Iron; [Griseofulvin results in decreased activity of FECH protein] which results in decreased uptake of Iron; [Porphobilinogen results in decreased activity of FECH protein] which results in increased abundance of Iron; heme arginate inhibits the reaction [[Griseofulvin results in decreased activity of FECH protein] which results in decreased uptake of Iron]
[pyridoxal isonicotinoyl hydrazone results in decreased abundance of Iron] which results in decreased expression of FECH protein
CTD PMID:15078340 PMID:30517741 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
JBrowse link
G Fen1 flap structure-specific endonuclease 1 multiple interactions ISO Iron binds to and inhibits the reaction [NEIL1 protein binds to FEN1 protein] CTD PMID:20622253 NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003
JBrowse link
G Flot1 flotillin 1 increases expression ISO Iron deficiency results in increased expression of FLOT1 mRNA CTD PMID:20368581 NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978
JBrowse link
G Fn3k fructosamine 3 kinase multiple interactions EXP [Tungsten co-treated with Nickel co-treated with Iron] results in increased expression of FN3K mRNA CTD PMID:24619124 NCBI chr10:106,700,302...106,715,903
Ensembl chr10:106,700,670...106,715,895
JBrowse link
G Fntb farnesyltransferase, CAAX box, beta increases expression EXP Iron deficiency results in increased expression of FNTB mRNA CTD PMID:16629162 NCBI chr 6:95,536,540...95,619,587
Ensembl chr 6:95,470,683...95,619,586
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of FOS protein; [Tungsten co-treated with Nickel co-treated with Iron] results in increased expression of FOS mRNA; Ergothioneine inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of FOS protein]; taxifolin inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of FOS protein] CTD PMID:24619124 PMID:32828744 PMID:33580994 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fth1 ferritin heavy chain 1 affects binding
multiple interactions
increases expression
affects metabolic processing
decreases expression
affects abundance
ISO
EXP
Iron binds to FTH1 protein
[Deferoxamine results in decreased abundance of Iron] which results in decreased expression of FTH1 mRNA; Iron deficiency promotes the reaction [Vitamin A deficiency results in decreased expression of FTH1 protein]
Iron results in increased expression of FTH1 mRNA
FTH1 protein affects the metabolism of Iron
Iron results in decreased expression of FTH1 mRNA
FTH1 protein affects the abundance of Iron
[CP gene mutant form results in increased abundance of Iron] which results in increased expression of FTH1 mRNA; [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of FTH1 mRNA; FTH1 protein inhibits the reaction [Iron results in increased abundance of Reactive Oxygen Species]
[[NBD peptide, mouse results in decreased expression of FTH1 mRNA] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species; [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of FTH1 protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of FTH1 protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of FTH1 protein]
CTD PMID:15893546 PMID:16424395 PMID:16448386 PMID:16988052 PMID:17070541 More... NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Ftl1 ferritin light chain 1 multiple interactions
increases expression
decreases expression
affects binding
decreases uptake
ISO
EXP
2-pyridylcarboxaldehyde isonicotinoylhydrazone inhibits the reaction [Doxorubicin promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]]; 2-pyridylcarboxaldehyde isonicotinoylhydrazone inhibits the reaction [Iron binds to [FTL protein binds to FTMT protein]]; [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of FTL mRNA; [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of FTL mRNA; [Hemin results in increased abundance of Iron] which results in increased expression of FTL mRNA; Deferoxamine inhibits the reaction [Doxorubicin promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]]; Deferoxamine inhibits the reaction [Iron binds to [FTL protein binds to FTMT protein]]; Doxorubicin promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]; Paraquat promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]; Razoxane inhibits the reaction [Iron binds to [FTL protein binds to FTMT protein]]; Vitamin K 3 promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]
Iron results in increased expression of FTL1 mRNA
Iron results in decreased expression of FTL1 mRNA
[Deferoxamine results in decreased abundance of Iron] which results in decreased expression of FTL mRNA; [Iron co-treated with Diethylnitrosamine] results in increased expression of FTL mRNA; Copper promotes the reaction [[Iron co-treated with Diethylnitrosamine] results in increased expression of FTL mRNA]
[CP gene mutant form results in increased abundance of Iron] which results in increased expression of FTL mRNA; [Iron co-treated with Ethanol] results in increased expression of FTL1 mRNA; Iron inhibits the reaction [Diethylnitrosamine results in decreased expression of FTL1 mRNA]; Quercetin inhibits the reaction [[Iron co-treated with Ethanol] results in increased expression of FTL1 mRNA]; Quercetin inhibits the reaction [Iron results in increased expression of FTL1 mRNA]
FTL protein mutant form results in decreased uptake of Iron
CTD PMID:12393473 PMID:12644586 PMID:15893546 PMID:16424395 PMID:16822677 More... NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
JBrowse link
G Ftmt ferritin mitochondrial multiple interactions
affects localization
affects binding
ISO 2-pyridylcarboxaldehyde isonicotinoylhydrazone inhibits the reaction [Doxorubicin promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]]; 2-pyridylcarboxaldehyde isonicotinoylhydrazone inhibits the reaction [Iron binds to [FTL protein binds to FTMT protein]]; [diallyl trisulfide results in decreased expression of FTMT protein] which results in increased abundance of Iron; Deferoxamine inhibits the reaction [Doxorubicin promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]]; Deferoxamine inhibits the reaction [Iron binds to [FTL protein binds to FTMT protein]]; Doxorubicin promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]; Paraquat promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]; Razoxane inhibits the reaction [Iron binds to [FTL protein binds to FTMT protein]]; Vitamin K 3 promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]
FTMT protein affects the localization of Iron
CTD PMID:12644586 PMID:16757684 PMID:21616139 NCBI chr18:45,758,874...45,760,123
Ensembl chr18:45,758,874...45,760,123
JBrowse link
G Fxn frataxin increases metabolic processing
increases abundance
affects metabolic processing
affects binding
ISO FXN protein results in increased metabolism of Iron
FXN gene mutant form results in increased abundance of Iron
FXN protein affects the metabolism of Iron
Iron binds to FXN protein
CTD PMID:16120311 PMID:16911956 PMID:17101455 PMID:17194590 NCBI chr 1:221,874,007...221,897,841
Ensembl chr 1:221,872,420...221,897,540
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression EXP Iron deficiency results in decreased expression of G6PC1 mRNA CTD PMID:16629162 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 multiple interactions
decreases expression
EXP [Iron deficiency co-treated with manganese chloride] results in decreased expression of GABBR2 mRNA; [Iron deficiency co-treated with manganese chloride] results in decreased expression of GABBR2 protein
Iron deficiency results in decreased expression of GABBR2 mRNA; Iron deficiency results in decreased expression of GABBR2 protein
CTD PMID:18771689 NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 decreases expression
increases expression
multiple interactions
EXP Iron deficiency results in decreased expression of GABRA1 mRNA
Iron deficiency results in increased expression of GABRA1 protein
[Iron deficiency co-treated with manganese chloride] results in increased expression of GABRA1 protein
CTD PMID:18771689 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
JBrowse link
G Gar1 GAR1 ribonucleoprotein increases expression EXP Iron deficiency results in increased expression of GAR1 mRNA CTD PMID:16629162 NCBI chr 2:218,375,231...218,382,509
Ensembl chr 2:218,375,353...218,382,524
JBrowse link
G Gas1 growth arrest-specific 1 multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of GAS1 mRNA; [Hemin results in increased abundance of Iron] which results in increased expression of GAS1 mRNA CTD PMID:12393473 NCBI chr17:4,482,014...4,485,155 JBrowse link
G Gas7 growth arrest specific 7 increases expression ISO Iron deficiency results in increased expression of GAS7 mRNA CTD PMID:20368581 NCBI chr10:52,152,728...52,383,276
Ensembl chr10:52,152,493...52,383,276
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases activity
decreases expression
multiple interactions
EXP
ISO
Iron results in increased activity of GCLC protein
Iron results in decreased expression of GCLC mRNA
Ursodeoxycholic Acid inhibits the reaction [Iron results in decreased expression of GCLC mRNA]
CTD PMID:17189828 PMID:19073151 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions
decreases expression
ISO Ursodeoxycholic Acid inhibits the reaction [Iron results in decreased expression of GCLM mRNA] CTD PMID:19073151 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gkn1 gastrokine 1 increases expression EXP Iron deficiency results in increased expression of GKN1 mRNA CTD PMID:16629162 NCBI chr 4:119,790,101...119,795,389
Ensembl chr 4:119,790,101...119,795,389
JBrowse link
G Gkn2 gastrokine 2 increases expression EXP Iron deficiency results in increased expression of GKN2 mRNA CTD PMID:16629162 NCBI chr 4:119,778,326...119,824,366
Ensembl chr 4:119,818,280...119,824,363
JBrowse link
G Gli3 GLI family zinc finger 3 multiple interactions ISO [Arsenic co-treated with Iron] results in decreased expression of GLI3 mRNA CTD PMID:31739468 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions
increases activity
EXP Capsaicin inhibits the reaction [Iron results in increased activity of GOT1 protein]; Curcumin inhibits the reaction [Iron results in increased activity of GOT1 protein] CTD PMID:16956363 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial increases expression EXP Iron deficiency results in increased expression of GPAM mRNA CTD PMID:16629162 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Gpr34 G protein-coupled receptor 34 increases expression ISO Iron deficiency results in increased expression of GPR34 mRNA CTD PMID:20368581 NCBI chr  X:9,104,829...9,113,796
Ensembl chr  X:9,104,565...9,148,601
JBrowse link
G Gprc5a G protein-coupled receptor, class C, group 5, member A increases expression EXP Iron deficiency results in increased expression of GPRC5A mRNA CTD PMID:16629162 NCBI chr 4:167,903,542...167,922,276
Ensembl chr 4:167,903,542...167,922,260
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases activity
EXP
ISO
[Iron-Dextran Complex results in increased abundance of Iron] which results in increased activity of GPT protein; Capsaicin inhibits the reaction [Iron results in increased activity of GPT protein]; Curcumin inhibits the reaction [Iron results in increased activity of GPT protein]; Ergothioneine inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased activity of GPT protein]; taxifolin inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased activity of GPT protein]
Drugs, Chinese Herbal inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased expression of ALT protein]; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased expression of ALT protein]
CTD PMID:16956363 PMID:27916511 PMID:32828744 PMID:33580994 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases response to substance
multiple interactions
ISO
EXP
GPX1 protein results in decreased susceptibility to Iron
[Iron co-treated with Hydrogen Peroxide] results in decreased expression of and results in decreased activity of GPX1 protein
CTD PMID:16721761 PMID:17280487 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression EXP Iron deficiency results in increased expression of GPX2 mRNA CTD PMID:16629162 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO [SB 216763 results in decreased activity of GSK3B protein] results in decreased susceptibility to [Arachidonic Acid co-treated with Iron] CTD PMID:19620254 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
ISO
EXP
[Iron-Dextran Complex results in increased abundance of Iron] which results in increased activity of GSR protein; Iron deficiency inhibits the reaction [Benzoyl Peroxide results in decreased activity of GSR protein]; Iron promotes the reaction [Benzoyl Peroxide results in decreased activity of GSR protein]; Iron promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of GSR protein]
[Arsenic co-treated with Cadmium co-treated with Lead co-treated with Mercury co-treated with Chromium co-treated with Nickel co-treated with Manganese co-treated with Iron] results in decreased activity of GSR protein
Iron results in decreased activity of GSR protein
CTD PMID:12067571 PMID:12504893 PMID:17176674 PMID:33393188 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gss glutathione synthetase multiple interactions
decreases expression
ISO Ursodeoxycholic Acid inhibits the reaction [Iron results in decreased expression of GSS mRNA] CTD PMID:19073151 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 multiple interactions
decreases expression
increases expression
EXP
ISO
[Copper co-treated with Diethylnitrosamine co-treated with Iron] results in decreased expression of GSTA2 mRNA
Iron results in decreased expression of GSTA1 protein
Iron results in increased expression of GSTA1 mRNA; Iron results in increased expression of GSTA1 protein
CTD PMID:11755321 PMID:20302851 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 multiple interactions EXP Iron results in increased expression of and results in increased activity of GSTA4 protein CTD PMID:7878679 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 multiple interactions EXP [Copper co-treated with Diethylnitrosamine co-treated with Iron] results in increased expression of GSTA5 mRNA CTD PMID:20302851 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Gsta6 glutathione S-transferase alpha 6 decreases expression
increases expression
ISO Iron results in decreased expression of GSTA1 protein
Iron results in increased expression of GSTA1 mRNA; Iron results in increased expression of GSTA1 protein
CTD PMID:11755321 NCBI chr 9:23,743,262...23,806,260
Ensembl chr 9:23,744,288...23,801,131
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases expression
increases expression
ISO Iron results in decreased expression of GSTM1 protein
Iron results in increased expression of GSTM1 mRNA; Iron results in increased expression of GSTM1 protein
CTD PMID:11755321 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions EXP [Copper co-treated with Diethylnitrosamine co-treated with Iron] results in increased expression of GSTM3 mRNA CTD PMID:20302851 NCBI chr 2:195,531,627...195,534,562
Ensembl chr 2:195,531,495...195,534,553
JBrowse link
G H3f4 H3.4 histone increases methylation
multiple interactions
ISO Iron results in increased methylation of H3-4 protein
[[Iron co-treated with Ketoglutaric Acids] results in increased activity of KDM3A protein] which results in decreased methylation of H3-4 protein
CTD PMID:16603237 PMID:21385672 NCBI chr10:43,740,797...43,741,207 JBrowse link
G Hamp hepcidin antimicrobial peptide decreases secretion
increases expression
decreases expression
affects expression
multiple interactions
affects metabolic processing
ISO
EXP
HAMP protein results in decreased secretion of Iron
Iron results in increased expression of HAMP protein
Iron results in increased expression of HAMP mRNA
Iron deficiency results in decreased expression of HAMP mRNA
Iron affects the expression of HAMP mRNA
[Acetaminophen results in decreased expression of HAMP mRNA] which results in increased abundance of Iron; [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of HAMP mRNA; Iron inhibits the reaction [Diethylnitrosamine results in decreased expression of HAMP mRNA]
HAMP protein affects the metabolism of Iron
[IL6 protein results in increased expression of HAMP protein] which results in decreased secretion of Iron; Iron affects the reaction [HAMP protein results in increased uptake of SLC40A1 protein]
CTD PMID:11113132 PMID:16460831 PMID:16574947 PMID:16648237 PMID:17116712 More... NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 multiple interactions ISO AHSP protein binds to and affects the folding of and affects the stability of [HBA1 protein binds to Iron] CTD PMID:16901899 NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392
JBrowse link
G Hbb hemoglobin subunit beta multiple interactions
affects abundance
ISO [HBB-B1 gene mutant form results in increased abundance of Iron] which results in decreased expression of TFR2 mRNA; [HBB-B1 gene mutant form results in increased abundance of Iron] which results in increased expression of SLC40A1 mRNA
HBB-B1 protein affects the abundance of Iron
CTD PMID:17018382 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
JBrowse link
G Hdac8 histone deacetylase 8 multiple interactions ISO Iron binds to and results in increased activity of HDAC8 protein CTD PMID:16681389 NCBI chr  X:67,385,288...67,593,014
Ensembl chr  X:67,385,289...67,592,923
JBrowse link
G Heph hephaestin affects metabolic processing
multiple interactions
ISO
EXP
HEPH protein affects the metabolism of Iron
[Zinc results in decreased expression of HEPH protein] which results in decreased uptake of Iron
CTD PMID:16614402 PMID:17194590 NCBI chr  X:61,151,131...61,402,980
Ensembl chr  X:61,296,345...61,402,980
JBrowse link
G Hfe homeostatic iron regulator increases uptake
affects abundance
multiple interactions
affects metabolic processing
decreases uptake
affects response to substance
increases abundance
ISO HFE gene mutant form results in increased uptake of Iron
HFE protein affects the abundance of Iron
[HFE gene mutant form co-treated with TFR2 gene mutant form] results in increased abundance of Iron
HFE protein affects the metabolism of Iron
HFE protein results in decreased uptake of Iron
[HFE protein binds to B2M protein binds to SLC11A2 protein] which results in decreased uptake of Iron; [HFE protein binds to TFR2 protein] which affects the susceptibility to Iron; HFE protein inhibits the reaction [TFRC protein results in increased uptake of Iron]; TNF gene SNP promotes the reaction [HFE protein mutant form results in increased uptake of Iron]
HFE protein affects the susceptibility to Iron
HFE gene polymorphism affects the abundance of Iron; HFE protein affects the abundance of Iron
HFE gene mutant form results in increased abundance of Iron; HFE gene polymorphism results in increased abundance of Iron
CTD PMID:10085150 PMID:12393473 PMID:16793930 PMID:16823846 PMID:16841247 More... NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
decreases expression
increases response to substance
decreases metabolic processing
ISO
EXP
[Deferoxamine results in decreased abundance of Iron] which results in increased expression of HIF1A mRNA; [Hemin results in decreased abundance of Iron] which results in increased expression of HIF1A mRNA; [Quercetin results in decreased abundance of Iron] which results in increased expression of HIF1A protein; Iron inhibits the reaction [galangin results in increased expression of HIF1A protein]; Iron inhibits the reaction [manganese chloride results in increased expression of HIF1A protein]; Iron inhibits the reaction [Nickel results in increased stability of HIF1A protein]; Iron inhibits the reaction [Quercetin results in increased expression of and affects the localization of HIF1A protein]; Iron inhibits the reaction [Quercetin results in increased expression of HIF1A protein]
Iron deficiency results in decreased expression of HIF1A mRNA
HIF1A protein results in increased susceptibility to Iron
HIF1A gene mutant form results in decreased metabolism of Iron
CTD PMID:12393473 PMID:16629162 PMID:16787915 PMID:16877034 PMID:17364964 More... NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hjv hemojuvelin BMP co-receptor affects metabolic processing ISO HJV protein affects the metabolism of Iron CTD PMID:17194590 NCBI chr 2:184,065,970...184,069,851
Ensembl chr 2:184,065,970...184,069,850
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 decreases expression EXP Iron deficiency results in decreased expression of HMGCS2 mRNA CTD PMID:16629162 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases metabolic processing
increases expression
EXP
ISO
[Copper co-treated with Diethylnitrosamine co-treated with Iron] results in increased expression of HMOX1 mRNA; [Iron co-treated with Diethylnitrosamine] results in increased expression of HMOX1 protein; Copper promotes the reaction [[Iron co-treated with Diethylnitrosamine] results in increased expression of HMOX1 protein]
HMOX1 protein results in increased metabolism of Iron
[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron; [[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species; [[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased expression of MMP1 mRNA; [[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein; [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of HMOX1 mRNA; [Ethanol results in increased expression of HMOX1 protein] which results in increased abundance of Iron; [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of HMOX1 mRNA; [Hemin results in increased abundance of Iron] which results in increased expression of HMOX1 mRNA; [HMOX1 protein results in increased degradation of Heme] which results in increased abundance of Iron; [Particulate Matter results in increased abundance of Iron] which results in increased expression of HMOX1 mRNA; Acetylcysteine inhibits the reaction [[[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein]; Iron promotes the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; zinc protoporphyrin inhibits the reaction [[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron]
Iron deficiency results in increased expression of HMOX1 mRNA; Iron results in increased expression of HMOX1 protein
CTD PMID:12393473 PMID:15602829 PMID:16439612 PMID:16629162 PMID:19136476 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hpgds hematopoietic prostaglandin D synthase increases expression ISO Iron deficiency results in increased expression of HPGDS mRNA CTD PMID:20368581 NCBI chr 4:94,368,426...94,397,931
Ensembl chr 4:94,373,342...94,397,883
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions
affects localization
EXP HRAS protein affects the reaction [Iron results in increased phosphorylation of AKT1 protein]; HRAS protein affects the reaction [Iron results in increased phosphorylation of MAPK1 protein]; HRAS protein affects the reaction [Iron results in increased phosphorylation of MAPK3 protein]; HRAS protein affects the reaction [Iron results in increased phosphorylation of NFKBIA protein]; Iron promotes the reaction [MAP3K7 protein binds to HRAS protein binds to PIK3R1 protein]
Iron affects the localization of HRAS protein
CTD PMID:17172471 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hsbp1l1 heat shock factor binding protein 1-like 1 decreases expression ISO Iron deficiency results in decreased expression of HSBP1L1 mRNA CTD PMID:20368581 NCBI chr18:73,682,286...73,690,061
Ensembl chr18:73,682,286...73,688,045
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions EXP [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of HSPA1A mRNA CTD PMID:22198552
G Hspa1l heat shock protein family A (Hsp70) member 1 like multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of HSPA1L mRNA; [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of HSPA1L mRNA; [Hemin results in increased abundance of Iron] which results in increased expression of HSPA1L mRNA CTD PMID:12393473 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions EXP [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of HSPA8 mRNA CTD PMID:22198552 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of HSPA9 mRNA; [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of HSPA9 mRNA; [Hemin results in increased abundance of Iron] which results in increased expression of HSPA9 mRNA CTD PMID:12393473 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions EXP [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of HSPB1 mRNA CTD PMID:22198552 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 multiple interactions EXP
ISO
[Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of HSPH1 mRNA
[Deferoxamine results in decreased abundance of Iron] which results in decreased expression of HSPH1 mRNA; [Hemin results in increased abundance of Iron] which results in increased expression of HSPH1 mRNA
CTD PMID:12393473 PMID:22198552 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Htt huntingtin decreases uptake ISO HTT protein mutant form results in decreased uptake of Iron CTD PMID:20547568 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:12633744 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression EXP Iron deficiency results in decreased expression of IDI1 mRNA CTD PMID:19821111 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
JBrowse link
G Ifng interferon gamma multiple interactions ISO Iron affects the reaction [[IL12A protein binds to IL12B protein] which results in increased secretion of IFNG protein]; Iron affects the reaction [IL18 protein results in increased secretion of IFNG protein] CTD PMID:15799959 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ift172 intraflagellar transport 172 increases expression EXP Iron deficiency results in increased expression of SLB mRNA CTD PMID:16629162 NCBI chr 6:25,081,933...25,121,271
Ensembl chr 6:25,081,980...25,120,860
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions EXP IGF1 protein inhibits the reaction [Carbon Tetrachloride results in increased abundance of Iron] CTD PMID:15745444 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression
multiple interactions
EXP
ISO
Iron deficiency results in increased expression of IGFBP3 mRNA
[Arsenic co-treated with Iron] results in decreased expression of IGFBP3 mRNA
CTD PMID:16629162 PMID:31739468 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions EXP deferiprone inhibits the reaction [Iron results in increased activity of [CHUK protein binds to IKBKB protein]]; Filipin inhibits the reaction [Iron results in increased activity of [CHUK protein binds to IKBKB protein]]; Iron results in increased activity of [CHUK protein binds to IKBKB protein]; N,N'-bis(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid inhibits the reaction [Iron results in increased activity of [CHUK protein binds to IKBKB protein]] CTD PMID:17172471 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Il12a interleukin 12A multiple interactions ISO Iron affects the reaction [[IL12A protein binds to IL12B protein] which results in increased secretion of IFNG protein] CTD PMID:15799959 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il12b interleukin 12B multiple interactions ISO Iron affects the reaction [[IL12A protein binds to IL12B protein] which results in increased secretion of IFNG protein] CTD PMID:15799959 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il18 interleukin 18 multiple interactions ISO Iron affects the reaction [IL18 protein results in increased secretion of IFNG protein] CTD PMID:15799959 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP [Iron co-treated with Diethylnitrosamine co-treated with Copper] results in increased expression of IL1A mRNA; [Iron co-treated with Diethylnitrosamine] results in increased expression of IL1A mRNA CTD PMID:20302851 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of IL1B protein; [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of IL1B mRNA; [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of IL1B protein; lipopolysaccharide A promotes the reaction [Iron results in increased secretion of IL1B protein]; taxifolin inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of IL1B protein]
[Particulate Matter results in increased abundance of Iron] which results in increased secretion of IL1B protein
CTD PMID:16958088 PMID:22198552 PMID:32007923 PMID:32828744 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions
increases secretion
ISO
EXP
[IL6 protein results in increased expression of HAMP protein] which results in decreased secretion of Iron
[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of IL6 protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of IL6 protein]
Iron results in increased secretion of IL6 protein
[Iron co-treated with Diethylnitrosamine co-treated with Copper] results in decreased expression of IL6 mRNA; [Iron co-treated with Diethylnitrosamine] results in decreased expression of IL6 mRNA; [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of IL6 protein; [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of IL6 mRNA; Ergothioneine inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of IL6 protein]; taxifolin inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of IL6 protein]
CTD PMID:16460831 PMID:20302851 PMID:22198552 PMID:26416317 PMID:32828744 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 multiple interactions ISO [Arsenic co-treated with Iron] results in increased expression of IP6K2 mRNA CTD PMID:31739468 NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166
JBrowse link
G Iqcd IQ motif containing D increases expression ISO Iron deficiency results in increased expression of IQCD mRNA CTD PMID:20368581 NCBI chr12:35,955,522...35,972,666 JBrowse link
G Ireb2 iron responsive element binding protein 2 affects metabolic processing
increases activity
multiple interactions
ISO
EXP
IREB2 protein affects the metabolism of Iron
Iron deficiency results in increased activity of IREB2 protein
Clofibrate inhibits the reaction [Iron deficiency results in increased activity of IREB2 protein]
CTD PMID:11969379 PMID:17194590 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
JBrowse link
G Irf8 interferon regulatory factor 8 decreases expression ISO Iron deficiency results in decreased expression of IRF8 mRNA CTD PMID:20368581 NCBI chr19:48,790,483...48,812,363
Ensembl chr19:48,790,588...48,811,829
JBrowse link
G Itga6 integrin subunit alpha 6 increases expression EXP Iron deficiency results in increased expression of ITGA6 mRNA CTD PMID:16629162 NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428
JBrowse link
G Itgam integrin subunit alpha M increases expression
multiple interactions
ISO Iron deficiency results in increased expression of ITGAM mRNA; Iron deficiency results in increased expression of ITGAM protein
Vitamin D promotes the reaction [Iron deficiency results in increased expression of ITGAM protein]
CTD PMID:20368581 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itgb2 integrin subunit beta 2 increases expression ISO Iron deficiency results in increased expression of ITGB2 mRNA CTD PMID:20368581 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
JBrowse link
G Itln1 intelectin 1 multiple interactions ISO ITLN1 protein binds to and results in increased uptake of Iron CTD PMID:16936804 NCBI chr13:83,932,234...83,958,243
Ensembl chr13:83,948,124...83,958,227
JBrowse link
G Jazf1 JAZF zinc finger 1 increases expression ISO Iron deficiency results in increased expression of JAZF1 mRNA CTD PMID:20368581 NCBI chr 4:81,879,501...82,183,241
Ensembl chr 4:81,881,061...82,183,100
JBrowse link
G Jchain joining chain of multimeric IgA and IgM increases expression EXP Iron deficiency results in increased expression of JCHAIN mRNA CTD PMID:16629162 NCBI chr14:19,538,560...19,546,384
Ensembl chr14:19,538,952...19,546,298
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO Iron deficiency results in increased expression of JUN mRNA
[Arsenic co-treated with Iron] results in increased expression of JUN mRNA; [Deferoxamine results in decreased abundance of Iron] which results in increased expression of JUN mRNA; [Hemin results in decreased abundance of Iron] which results in increased expression of JUN mRNA
CTD PMID:12393473 PMID:20368581 PMID:31739468 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 increases expression EXP Iron deficiency results in increased expression of KCNE3 mRNA CTD PMID:16629162 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020
JBrowse link
G Kdm3a lysine demethylase 3A multiple interactions ISO [[Iron co-treated with Ketoglutaric Acids] results in increased activity of KDM3A protein] which results in decreased methylation of H3-4 protein CTD PMID:16603237 NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression ISO Iron deficiency results in decreased expression of KIT mRNA CTD PMID:20368581 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Klhdc7b kelch domain containing 7B increases expression ISO Iron deficiency results in increased expression of KLHDC7B mRNA CTD PMID:20368581 NCBI chr 7:120,452,081...120,456,094
Ensembl chr 7:120,453,932...120,455,737
JBrowse link
G Lamc2 laminin subunit gamma 2 increases expression EXP Iron deficiency results in increased expression of LAMC2 mRNA CTD PMID:16629162 NCBI chr13:65,284,664...65,344,200
Ensembl chr13:65,284,664...65,344,200
JBrowse link
G Lamp5 lysosomal-associated membrane protein family, member 5 decreases expression ISO Iron deficiency results in decreased expression of LAMP5 mRNA CTD PMID:20368581 NCBI chr 3:123,372,462...123,384,970
Ensembl chr 3:123,372,462...123,384,952
JBrowse link
G Lcn2 lipocalin 2 affects metabolic processing
increases expression
ISO LCN2 protein affects the metabolism of Iron
Iron results in increased expression of LCN2 mRNA; Iron results in increased expression of LCN2 protein
CTD PMID:17194590 PMID:17350462 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Lig3 DNA ligase 3 decreases activity ISO Iron results in decreased activity of LIG3 protein CTD PMID:20622253 NCBI chr10:67,717,796...67,741,141
Ensembl chr10:67,717,812...67,798,414
JBrowse link
G Lox lysyl oxidase multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in increased expression of LOX mRNA; [Hemin results in decreased abundance of Iron] which results in increased expression of LOX mRNA CTD PMID:12393473 NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 decreases expression EXP Iron deficiency results in decreased expression of LPAR1 mRNA CTD PMID:19821111 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895
JBrowse link
G Lrrc25 leucine rich repeat containing 25 increases expression ISO Iron deficiency results in increased expression of LRRC25 mRNA CTD PMID:20368581 NCBI chr16:18,806,888...18,813,726
Ensembl chr16:18,806,890...18,813,671
JBrowse link
G Lta lymphotoxin alpha multiple interactions EXP [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of LTA mRNA CTD PMID:22198552 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859
JBrowse link
G Ly75 lymphocyte antigen 75 decreases expression ISO Iron deficiency results in decreased expression of LY75 mRNA CTD PMID:20368581 NCBI chr 3:44,764,702...44,852,219
Ensembl chr 3:44,765,122...44,852,374
JBrowse link
G Lypla1 lysophospholipase 1 decreases expression EXP Iron deficiency results in decreased expression of LYPLA1 mRNA CTD PMID:19821111 NCBI chr 5:14,679,605...14,708,774
Ensembl chr 5:14,679,606...14,708,746
JBrowse link
G Maoa monoamine oxidase A decreases expression EXP Iron deficiency results in decreased expression of MAOA mRNA CTD PMID:16629162 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO Iron affects the reaction [Deferoxamine results in increased expression of MAP1LC3B protein]; Iron affects the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone results in increased expression of MAP1LC3B protein] CTD PMID:25301941 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 multiple interactions
increases phosphorylation
EXP Filipin inhibits the reaction [Iron promotes the reaction [MAP3K7 protein results in increased phosphorylation of MAP2K6 protein]]; Filipin inhibits the reaction [Iron results in increased phosphorylation of MAP2K6 protein]; Iron promotes the reaction [MAP3K7 protein results in increased phosphorylation of MAP2K6 protein] CTD PMID:17172471 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 multiple interactions EXP MAP3K14 protein affects the reaction [Iron results in increased phosphorylation of NFKBIA protein]; MAP3K14 protein affects the reaction [Iron results in increased secretion of TNF protein] CTD PMID:17172471 NCBI chr10:88,165,349...88,215,558
Ensembl chr10:88,165,351...88,215,523
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 multiple interactions
increases activity
affects localization
EXP Filipin inhibits the reaction [Iron promotes the reaction [MAP3K7 protein results in increased phosphorylation of MAP2K6 protein]]; Filipin inhibits the reaction [Iron results in increased activity of MAP3K7 protein]; Iron promotes the reaction [MAP3K7 protein binds to HRAS protein binds to PIK3R1 protein]; Iron promotes the reaction [MAP3K7 protein results in increased phosphorylation of MAP2K6 protein]; MAP3K7 protein affects the reaction [Iron results in increased phosphorylation of AKT1 protein]; MAP3K7 protein affects the reaction [Iron results in increased phosphorylation of NFKBIA protein]; MAP3K7 protein affects the reaction [Iron results in increased secretion of TNF protein]
Iron affects the localization of MAP3K7 protein
CTD PMID:17172471 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
EXP
ISO
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Iron results in increased phosphorylation of MAPK1 protein]; [Vanadium co-treated with Iron] results in increased phosphorylation of MAPK1 protein; Deferiprone inhibits the reaction [Iron results in increased phosphorylation of MAPK1 protein]; Filipin inhibits the reaction [Iron results in increased phosphorylation of MAPK1 protein]; HRAS protein affects the reaction [Iron results in increased phosphorylation of MAPK1 protein]; Iron promotes the reaction [Asbestos, Amosite results in increased phosphorylation of MAPK1 protein]; PIK3R1 protein affects the reaction [Iron results in increased phosphorylation of MAPK1 protein]; SB 203580 promotes the reaction [Iron results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Iron results in increased phosphorylation of MAPK1 protein]
[ferrous chloride results in increased abundance of Iron] which results in increased phosphorylation of MAPK1 protein
[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of MAPK1 protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of MAPK1 protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of MAPK1 protein]; Iron promotes the reaction [Arsenic results in increased phosphorylation of and results in increased activity of MAPK1 protein]
CTD PMID:11306436 PMID:16728372 PMID:17172471 PMID:23100159 PMID:30914277 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
EXP
ISO
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Iron results in increased phosphorylation of MAPK3 protein]; [Aluminum co-treated with Iron] results in increased phosphorylation of MAPK3 protein; [Vanadium co-treated with Iron] results in increased phosphorylation of MAPK3 protein; deferiprone inhibits the reaction [Iron results in increased phosphorylation of MAPK3 protein]; Filipin inhibits the reaction [Iron results in increased phosphorylation of MAPK3 protein]; HRAS protein affects the reaction [Iron results in increased phosphorylation of MAPK3 protein]; Iron promotes the reaction [Asbestos, Amosite results in increased phosphorylation of MAPK3 protein]; PIK3R1 protein affects the reaction [Iron results in increased phosphorylation of MAPK3 protein]; SB 203580 promotes the reaction [Iron results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Iron results in increased phosphorylation of MAPK3 protein]
[ferrous chloride results in increased abundance of Iron] which results in increased phosphorylation of MAPK3 protein
[Iron co-treated with Arsenic] results in increased phosphorylation of and results in increased activity of MAPK3 protein; [Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of MAPK3 protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of MAPK3 protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of MAPK3 protein]
CTD PMID:11306436 PMID:16728372 PMID:17172471 PMID:23100159 PMID:30914277 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate increases expression EXP Iron deficiency results in increased expression of MARCKS mRNA CTD PMID:16629162 NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
JBrowse link
G Mcemp1 mast cell-expressed membrane protein 1 increases expression ISO Iron deficiency results in increased expression of MCEMP1 mRNA CTD PMID:20368581 NCBI chr12:1,721,781...1,727,350
Ensembl chr12:1,718,730...1,725,986
JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 multiple interactions
increases expression
ISO [Ethanol co-treated with Iron] results in increased expression of MCOLN1 mRNA; [Ethanol co-treated with Iron] results in increased expression of MCOLN1 protein; Quercetin inhibits the reaction [[Ethanol co-treated with Iron] results in increased expression of MCOLN1 mRNA]; Quercetin inhibits the reaction [[Ethanol co-treated with Iron] results in increased expression of MCOLN1 protein]; Quercetin inhibits the reaction [Iron results in increased expression of MCOLN1 mRNA]; Quercetin inhibits the reaction [Iron results in increased expression of MCOLN1 protein]
Iron results in increased expression of MCOLN1 mRNA; Iron results in increased expression of MCOLN1 protein
CTD PMID:24569067 NCBI chr12:1,560,341...1,574,252
Ensembl chr12:1,560,359...1,574,252
JBrowse link
G Mctp1 multiple C2 and transmembrane domain containing 1 increases expression ISO Iron deficiency results in increased expression of MCTP1 mRNA CTD PMID:20368581 NCBI chr 2:6,071,408...6,761,833
Ensembl chr 2:6,065,808...6,761,833
JBrowse link
G Me1 malic enzyme 1 increases expression ISO Iron deficiency results in increased expression of ME1 mRNA CTD PMID:20368581 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Mif macrophage migration inhibitory factor multiple interactions EXP [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of MIF mRNA CTD PMID:22198552 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Miox myo-inositol oxygenase affects binding ISO [MIOX protein binds to Iron] which binds to Inositol CTD PMID:17012379 NCBI chr 7:120,405,031...120,407,529
Ensembl chr 7:120,405,031...120,407,537
JBrowse link
G Mir196b microRNA 196b multiple interactions ISO [Air Pollutants, Occupational results in increased abundance of Iron] which results in increased expression of MIR196B mRNA CTD PMID:27506416 NCBI chr 4:81,330,487...81,330,571
Ensembl chr 4:81,330,487...81,330,571
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO [[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased expression of MMP1 mRNA; [[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein; Acetylcysteine inhibits the reaction [[[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein] CTD PMID:19136476 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity
EXP [Hexachlorocyclohexane co-treated with Iron] results in increased activity of MPO protein
Iron results in increased activity of MPO protein
CTD PMID:11141352 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Ms4a6a membrane spanning 4-domains A6A decreases expression ISO Iron deficiency results in decreased expression of MS4A6A mRNA CTD PMID:20368581 NCBI chr 1:208,401,465...208,414,831
Ensembl chr 1:208,401,466...208,414,758
JBrowse link
G Ms4a7 membrane spanning 4-domains A7 increases expression EXP Iron deficiency results in increased expression of MS4A7 mRNA CTD PMID:16629162 NCBI chr 1:207,968,761...207,984,812
Ensembl chr 1:207,968,761...207,983,260
JBrowse link
G Mt1 metallothionein 1 increases expression
multiple interactions
EXP
ISO
Iron deficiency results in increased expression of MT1A; Iron deficiency results in increased expression of MT1A mRNA
Iron deficiency results in increased expression of MT1 mRNA
ATP7A gene mutant form promotes the reaction [Iron deficiency results in increased expression of MT1 mRNA]
[Zinc co-treated with Iron] results in increased expression of and affects the localization of MT1A protein; Iron results in increased expression of and affects the localization of MT1A protein
CTD PMID:16629162 PMID:17241390 PMID:21852364 PMID:23776592 PMID:24089420 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
JBrowse link
G Mt2A metallothionein 2A multiple interactions
affects abundance
increases expression
ISO
EXP
[Deferoxamine results in decreased abundance of Iron] which results in increased expression of MT2A mRNA; [ferric ammonium citrate results in decreased abundance of Iron] which results in increased expression of MT2A mRNA; [Hemin results in decreased abundance of Iron] which results in increased expression of MT2A mRNA
MT2A gene SNP affects the abundance of Iron
Iron deficiency results in increased expression of MT2 mRNA
[Zinc co-treated with Iron] results in increased expression of and affects the localization of MT2A protein; Iron results in increased expression of and affects the localization of MT2A protein
Iron deficiency results in increased expression of MT2A mRNA
CTD PMID:12393473 PMID:16629162 PMID:17241390 PMID:21328412 PMID:24089420 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mvd mevalonate diphosphate decarboxylase increases expression EXP Iron deficiency results in increased expression of MVD mRNA CTD PMID:19821111 NCBI chr19:50,496,366...50,506,389
Ensembl chr19:50,496,367...50,507,971
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of MYC mRNA; [Hemin results in increased abundance of Iron] which results in increased expression of MYC mRNA CTD PMID:12393473 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Ndrg1 N-myc downstream regulated 1 multiple interactions ISO [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone binds to Iron] which results in increased expression of NDRG1 protein; NDRG1 protein results in decreased susceptibility to [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone binds to Iron] CTD PMID:24532803 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 affects expression ISO Iron affects the expression of NDUFS1 protein CTD PMID:11313346 NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 increases expression EXP Iron deficiency results in increased expression of NEDD9 mRNA CTD PMID:16629162 NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019
JBrowse link
G Neil1 nei-like DNA glycosylase 1 multiple interactions ISO Curcumin inhibits the reaction [Iron binds to and results in decreased activity of NEIL1 protein]; Edetic Acid inhibits the reaction [Iron binds to and results in decreased activity of NEIL1 protein]; Iron binds to and affects the folding of and results in decreased activity of NEIL1 protein; Iron binds to and inhibits the reaction [NEIL1 protein binds to FEN1 protein]; Iron binds to and inhibits the reaction [NEIL1 protein binds to POLB protein] CTD PMID:20622253 NCBI chr 8:57,550,142...57,556,884
Ensembl chr 8:57,550,147...57,556,258
JBrowse link
G Neil2 nei-like DNA glycosylase 2 multiple interactions ISO Iron binds to and results in decreased activity of NEIL2 protein CTD PMID:20622253 NCBI chr15:37,444,676...37,454,863
Ensembl chr15:37,445,381...37,454,863
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases activity
EXP
ISO
[Iron co-treated with Diethylnitrosamine co-treated with Copper] results in increased expression of NFE2L2 mRNA
[Particulate Matter results in increased abundance of Iron] which affects the localization of NFE2L2 protein; [Particulate Matter results in increased abundance of Iron] which results in increased expression of NFE2L2 mRNA
Iron results in increased activity of NFE2L2 promoter
NFE2L2 protein promotes the reaction [SLC40A1 protein results in increased export of Iron]
CTD PMID:20302851 PMID:21303654 PMID:21643505 PMID:26419736 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfib nuclear factor I/B multiple interactions ISO [Arsenic co-treated with Iron] results in decreased expression of NFIB mRNA CTD PMID:31739468 NCBI chr 5:96,759,208...96,973,092
Ensembl chr 5:96,764,653...96,975,479
JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated increases expression ISO Iron deficiency results in increased expression of NFIL3 mRNA CTD PMID:20368581 NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases phosphorylation
EXP
ISO
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Iron results in increased phosphorylation of NFKBIA protein]; [Copper co-treated with Diethylnitrosamine co-treated with Iron] results in decreased expression of NFKBIA mRNA; [Iron co-treated with Diethylnitrosamine] results in decreased expression of NFKBIA mRNA; HRAS protein affects the reaction [Iron results in increased phosphorylation of NFKBIA protein]; MAP3K14 protein affects the reaction [Iron results in increased phosphorylation of NFKBIA protein]; MAP3K7 protein affects the reaction [Iron results in increased phosphorylation of NFKBIA protein]; PIK3R1 protein affects the reaction [Iron results in increased phosphorylation of NFKBIA protein]; SB 203580 promotes the reaction [Iron results in increased phosphorylation of NFKBIA protein]; U 0126 inhibits the reaction [Iron results in increased phosphorylation of NFKBIA protein]
[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of NFKBIA protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of NFKBIA protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of NFKBIA protein]
CTD PMID:17172471 PMID:20302851 PMID:33285147 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ngb neuroglobin decreases uptake ISO NGB protein results in decreased uptake of Iron CTD PMID:19154338 NCBI chr 6:106,744,378...106,749,830
Ensembl chr 6:106,744,378...106,749,830
JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 increases expression ISO Iron deficiency results in increased expression of NLRC4 mRNA CTD PMID:20368581 NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248
JBrowse link
G Nmt2 N-myristoyltransferase 2 multiple interactions EXP [Tungsten co-treated with Nickel co-treated with Iron] results in increased expression of NMT2 mRNA CTD PMID:24619124 NCBI chr17:74,917,833...74,964,788
Ensembl chr17:74,917,833...74,961,080
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP
ISO
[Aluminum co-treated with Iron] results in increased expression of NOS2 protein; [Iron co-treated with Diethylnitrosamine co-treated with Copper] results in decreased expression of NOS2 mRNA; [Iron co-treated with Diethylnitrosamine] results in decreased expression of NOS2 mRNA; [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of NOS2 mRNA
Iron inhibits the reaction [Asbestos, Crocidolite results in increased expression of NOS2 mRNA]; Iron inhibits the reaction [Asbestos, Crocidolite results in increased expression of NOS2 protein]
CTD PMID:11461780 PMID:16728372 PMID:20302851 PMID:22198552 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 decreases abundance ISO NPC1 gene mutant form results in decreased abundance of Iron CTD PMID:24901380 NCBI chr18:3,379,482...3,425,100
Ensembl chr18:3,379,482...3,425,049
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases reduction
multiple interactions
ISO NQO1 protein results in increased reduction of Iron
[Particulate Matter results in increased abundance of Iron] which results in increased expression of NQO1 mRNA
CTD PMID:17178108 PMID:26419736 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Ocln occludin multiple interactions EXP Iron inhibits the reaction [Lead results in decreased expression of OCLN mRNA]; Iron inhibits the reaction [Lead results in decreased expression of OCLN protein] CTD PMID:17234227 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions
increases activity
ISO Iron affects the reaction [3-chloroperbenzoic acid results in increased activity of ODC1 protein]; Iron deficiency inhibits the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]; Iron promotes the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]; Iron promotes the reaction [cumene hydroperoxide results in increased activity of ODC1 protein]; Iron promotes the reaction [Hydrogen Peroxide results in increased activity of ODC1 protein]; Iron promotes the reaction [mezerein results in increased activity of ODC1 protein]; Iron promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]
Iron results in increased activity of ODC1 protein
CTD PMID:7653998 PMID:12065085 PMID:12067571 PMID:12504893 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Opn3 opsin 3 decreases expression ISO Iron deficiency results in decreased expression of OPN3 mRNA CTD PMID:20368581 NCBI chr13:87,589,330...87,619,847
Ensembl chr13:87,589,333...87,619,847
JBrowse link
G Osbpl11 oxysterol binding protein-like 11 increases expression ISO Iron deficiency results in increased expression of OSBPL11 mRNA CTD PMID:20368581 NCBI chr11:67,533,669...67,616,795
Ensembl chr11:67,533,672...67,596,444
JBrowse link
G P2rx7 purinergic receptor P2X 7 increases expression ISO Iron deficiency results in increased expression of P2RX7 mRNA CTD PMID:20368581 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 increases expression EXP Iron deficiency results in increased expression of P4HA1 mRNA CTD PMID:16629162 NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
JBrowse link
G P4htm prolyl 4-hydroxylase, transmembrane multiple interactions ISO Iron inhibits the reaction [manganese chloride results in decreased activity of P4HTM protein] CTD PMID:19263519 NCBI chr 8:109,274,629...109,292,802
Ensembl chr 8:109,274,626...109,292,473
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [Acetaminophen co-treated with [ferric nitrate results in increased abundance of Iron]] results in increased cleavage of PARP1 protein; [Arachidonic Acid co-treated with Iron] results in increased expression of PARP1 protein modified form; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased expression of PARP1 protein modified form]; Rifampin inhibits the reaction [[Acetaminophen co-treated with [ferric nitrate results in increased abundance of Iron]] results in increased cleavage of PARP1 protein] CTD PMID:30626086 PMID:31678598 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pcgf5 polycomb group ring finger 5 increases expression ISO Iron deficiency results in increased expression of PCGF5 mRNA CTD PMID:20368581 NCBI chr 1:234,063,854...234,180,022
Ensembl chr 1:234,063,892...234,175,315
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 decreases expression EXP Iron deficiency results in decreased expression of PCK1 mRNA CTD PMID:16629162 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression
multiple interactions
EXP Iron deficiency results in increased expression of PCNA mRNA
[taxifolin co-treated with [Iron-Dextran Complex results in increased abundance of Iron]] results in increased expression of PCNA protein
CTD PMID:16629162 PMID:32828744 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pctp phosphatidylcholine transfer protein decreases expression EXP Iron deficiency results in decreased expression of PCTP mRNA CTD PMID:19821111 NCBI chr10:74,808,887...74,856,260
Ensembl chr10:74,808,887...74,849,867
JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions EXP Iron promotes the reaction [Asbestos, Amosite results in increased expression of PDGFA mRNA] CTD PMID:11306436 PMID:12475806 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression EXP Iron deficiency results in increased expression of PDK4 mRNA CTD PMID:16629162 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 multiple interactions ISO [cobaltous chloride results in decreased abundance of Iron] which results in increased expression of PFKFB4 mRNA; [Deferoxamine results in decreased abundance of Iron] which results in increased expression of PFKFB4 mRNA CTD PMID:16025159 NCBI chr 8:109,643,558...109,687,006
Ensembl chr 8:109,643,937...109,685,634
JBrowse link
G Phospho1 phosphoethanolamine/phosphocholine phosphatase 1 decreases expression EXP Iron deficiency results in decreased expression of PHOSPHO1 mRNA CTD PMID:16629162 NCBI chr10:80,762,062...80,769,596
Ensembl chr10:80,760,792...80,770,342
JBrowse link
G Pik3c2b phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta increases expression EXP Iron deficiency results in increased expression of PIK3C2B mRNA CTD PMID:16629162 NCBI chr13:44,494,673...44,555,663
Ensembl chr13:44,495,050...44,555,612
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha multiple interactions EXP [Iron-Dextran Complex results in increased abundance of Iron] which results in decreased expression of PIK3CA protein; [Iron-Dextran Complex results in increased abundance of Iron] which results in decreased phosphorylation of PIK3CA protein; Ergothioneine inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in decreased expression of PIK3CA protein]; taxifolin inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in decreased phosphorylation of PIK3CA protein] CTD PMID:32828744 PMID:33580994 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions EXP Iron promotes the reaction [MAP3K7 protein binds to HRAS protein binds to PIK3R1 protein]; PIK3R1 protein affects the reaction [Iron results in increased phosphorylation of AKT1 protein]; PIK3R1 protein affects the reaction [Iron results in increased phosphorylation of MAPK1 protein]; PIK3R1 protein affects the reaction [Iron results in increased phosphorylation of MAPK3 protein]; PIK3R1 protein affects the reaction [Iron results in increased phosphorylation of NFKBIA protein]; PIK3R1 protein affects the reaction [Iron results in increased secretion of TNF protein] CTD PMID:17172471 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase increases expression ISO Iron deficiency results in increased expression of PIM1 mRNA CTD PMID:20368581 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
JBrowse link
G Pip5k1b phosphatidylinositol-4-phosphate 5-kinase type 1 beta increases expression ISO Iron deficiency results in increased expression of PIP5K1B mRNA CTD PMID:20368581 NCBI chr 1:221,907,220...222,183,672
Ensembl chr 1:221,914,159...222,183,672
JBrowse link
G Pla2g1b phospholipase A2 group IB increases expression EXP Iron deficiency results in increased expression of PLA2G1B mRNA CTD PMID:19821111 NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226
JBrowse link
G Pla2g4a phospholipase A2 group IVA decreases expression EXP Iron deficiency results in decreased expression of PLA2G4A mRNA CTD PMID:19821111 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Plaa phospholipase A2, activating protein decreases expression EXP Iron deficiency results in decreased expression of PLAA mRNA CTD PMID:19821111 NCBI chr 5:109,428,600...109,460,373
Ensembl chr 5:109,428,265...109,460,282
JBrowse link
G Pld4 phospholipase D family, member 4 decreases expression ISO Iron deficiency results in decreased expression of PLD4 mRNA CTD PMID:20368581 NCBI chr 6:131,818,860...131,827,457
Ensembl chr 6:131,818,860...131,826,376
JBrowse link
G Plpp1 phospholipid phosphatase 1 increases expression ISO Iron deficiency results in increased expression of PLPP1 mRNA CTD PMID:20368581 NCBI chr 2:44,439,002...44,500,430
Ensembl chr 2:44,438,994...44,501,268
JBrowse link
G Plscr1 phospholipid scramblase 1 decreases expression EXP Iron deficiency results in decreased expression of PLSCR1 mRNA CTD PMID:19821111 NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692
JBrowse link
G Pmp22 peripheral myelin protein 22 increases expression
multiple interactions
ISO
EXP
Iron deficiency results in increased expression of PMP22 mRNA
[Deferoxamine results in decreased abundance of Iron] which results in decreased expression of PMP22 mRNA; [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of PMP22 mRNA; [Hemin results in decreased abundance of Iron] which results in increased expression of PMP22 mRNA
CTD PMID:12393473 PMID:16629162 PMID:20368581 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
JBrowse link
G Pmvk phosphomevalonate kinase increases expression EXP Iron deficiency results in increased expression of PMVK mRNA CTD PMID:19821111 NCBI chr 2:174,876,586...174,886,365
Ensembl chr 2:174,876,657...174,886,364
JBrowse link
G Pnlip pancreatic lipase increases expression EXP Iron deficiency results in increased expression of PNLIP mRNA CTD PMID:19821111 NCBI chr 1:257,774,012...257,811,656
Ensembl chr 1:257,798,581...257,811,654
JBrowse link
G Pnliprp1 pancreatic lipase-related protein 1 increases expression EXP Iron deficiency results in increased expression of PNLIPRP1 mRNA CTD PMID:19821111 NCBI chr 1:257,867,885...257,883,514
Ensembl chr 1:257,867,885...257,883,514
JBrowse link
G Pnliprp2 pancreatic lipase related protein 2 decreases expression EXP Iron deficiency results in decreased expression of PNLIPRP2 mRNA CTD PMID:16629162 NCBI chr 1:257,897,766...257,916,434
Ensembl chr 1:257,897,766...257,916,434
JBrowse link
G Poglut2 protein O-glucosyltransferase 2 increases expression ISO Iron deficiency results in increased expression of POGLUT2 mRNA CTD PMID:20368581 NCBI chr 9:46,256,388...46,268,714
Ensembl chr 9:46,256,390...46,268,532
JBrowse link
G Polb DNA polymerase beta multiple interactions ISO Iron binds to and inhibits the reaction [NEIL1 protein binds to POLB protein] CTD PMID:20622253 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812
JBrowse link
G Polr3e RNA polymerase III subunit E multiple interactions EXP [Tungsten co-treated with Nickel co-treated with Iron] results in increased expression of POLR3E mRNA CTD PMID:24619124 NCBI chr 1:175,466,091...175,494,679
Ensembl chr 1:175,466,127...175,494,667
JBrowse link
G Pon1 paraoxonase 1 multiple interactions ISO
EXP
[Iron co-treated with Ascorbic Acid] results in decreased activity of PON1 protein; [Iron co-treated with Ascorbic Acid] results in decreased expression of PON1 protein; Butylated Hydroxytoluene inhibits the reaction [[Iron co-treated with Ascorbic Acid] results in decreased expression of PON1 protein] CTD PMID:16052486 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions ISO [[Iron co-treated with POR protein] results in increased metabolism of Diquat] which results in increased abundance of Hydroxyl Radical; [[Iron co-treated with POR protein] results in increased metabolism of Paraquat] which results in increased abundance of Hydroxyl Radical; [Iron co-treated with POR protein] results in increased metabolism of Diquat; [Iron co-treated with POR protein] results in increased metabolism of Paraquat CTD PMID:21215309 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO Iron deficiency results in increased expression of PPARG mRNA CTD PMID:20368581 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppp1r16b protein phosphatase 1, regulatory subunit 16B increases expression ISO Iron deficiency results in increased expression of PPP1R16B mRNA CTD PMID:20368581 NCBI chr 3:147,323,652...147,419,658
Ensembl chr 3:147,324,126...147,418,937
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B increases expression EXP Iron deficiency results in increased expression of PPP1R1B mRNA CTD PMID:16629162 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775
JBrowse link
G Prg3 proteoglycan 3, pro eosinophil major basic protein 2 decreases expression ISO Iron deficiency results in decreased expression of PRG3 mRNA CTD PMID:20368581 NCBI chr 3:70,071,970...70,078,103
Ensembl chr 3:70,072,497...70,078,102
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 decreases expression EXP Iron deficiency results in decreased expression of PRKAA1 mRNA CTD PMID:19821111 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prnp prion protein multiple interactions
decreases abundance
ISO [Hydrogen Peroxide co-treated with Iron] results in increased cleavage of PRNP protein; Edetic Acid inhibits the reaction [[Hydrogen Peroxide co-treated with Iron] results in increased cleavage of PRNP protein]; Iron, Dietary inhibits the reaction [PRNP gene mutant form results in decreased abundance of Iron] CTD PMID:16595185 PMID:23478311 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
JBrowse link
G Prtn3 proteinase 3 decreases expression ISO Iron deficiency results in decreased expression of PRTN3 mRNA CTD PMID:20368581 NCBI chr 7:9,822,123...9,831,300
Ensembl chr 7:9,822,122...9,831,944
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP
ISO
[Copper co-treated with Diethylnitrosamine co-treated with Iron] results in increased expression of PTGS2 protein
[Arsenic co-treated with Iron] results in increased expression of PTGS2 mRNA
CTD PMID:20302851 PMID:31739468 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Pthlh parathyroid hormone-like hormone multiple interactions ISO [Arsenic co-treated with Iron] results in increased expression of PTHLH mRNA CTD PMID:31739468 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847
JBrowse link
G Ptx3 pentraxin 3 increases expression ISO Iron deficiency results in increased expression of PTX3 mRNA CTD PMID:20368581 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323
JBrowse link
G Pxdn peroxidasin multiple interactions ISO [Arsenic co-treated with Iron] results in decreased expression of PXDN mRNA CTD PMID:31739468 NCBI chr 6:46,580,749...46,658,345
Ensembl chr 6:46,580,761...46,658,345
JBrowse link
G Rab30 RAB30, member RAS oncogene family decreases expression EXP Iron deficiency results in decreased expression of RAB30 mRNA CTD PMID:16629162 NCBI chr 1:146,803,652...146,898,369
Ensembl chr 1:146,803,714...146,892,181
JBrowse link
G Rasd1 ras related dexamethasone induced 1 multiple interactions EXP Nitric Oxide promotes the reaction [[RASD1 protein binds to ACBD3 protein binds to SLC11A2 protein] which results in increased uptake of Iron] CTD PMID:16908409 NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186
JBrowse link
G Rbp7 retinol binding protein 7 increases expression EXP Iron deficiency results in increased expression of RBP7 mRNA CTD PMID:16629162 NCBI chr 5:159,889,723...159,894,338
Ensembl chr 5:159,889,723...159,894,339
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP
[Iron-Dextran Complex results in increased abundance of Iron] which affects the localization of RELA protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which affects the localization of RELA protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which affects the localization of RELA protein]; SB 203580 inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which affects the localization of RELA protein]; U 0126 inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which affects the localization of RELA protein]
[Iron-Dextran Complex results in increased abundance of Iron] which affects the localization of RELA protein; Ergothioneine inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which affects the localization of RELA protein]
CTD PMID:33285147 PMID:33580994 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit increases expression ISO Iron deficiency results in increased expression of RELB mRNA CTD PMID:20368581 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
JBrowse link
G Retn resistin increases expression ISO Iron deficiency results in increased expression of RETN mRNA CTD PMID:20368581 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620
JBrowse link
G Rgs1 regulator of G-protein signaling 1 increases expression ISO Iron deficiency results in increased expression of RGS1 mRNA CTD PMID:20368581 NCBI chr13:56,018,529...56,022,939
Ensembl chr13:56,018,554...56,022,984
JBrowse link
G Rgs2 regulator of G-protein signaling 2 increases expression ISO Iron deficiency results in increased expression of RGS2 mRNA CTD PMID:20368581 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
G Rho rhodopsin multiple interactions ISO [Iron-Dextran Complex results in increased abundance of Iron] which results in decreased expression of RHO mRNA; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in decreased expression of RHO mRNA] CTD PMID:33285147 NCBI chr 4:148,975,597...148,988,693
Ensembl chr 4:148,980,611...148,985,773
JBrowse link
G Rhob ras homolog family member B increases expression EXP Iron deficiency results in increased expression of RHOB mRNA CTD PMID:16629162 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
JBrowse link
G Rnase4 ribonuclease A family member 4 increases expression ISO Iron deficiency results in increased expression of RNASE4 mRNA CTD PMID:20368581 NCBI chr15:24,312,765...24,330,116
Ensembl chr15:24,312,464...24,330,117
JBrowse link
G Ropn1l rhophilin associated tail protein 1-like decreases expression ISO Iron deficiency results in decreased expression of ROPN1L mRNA CTD PMID:20368581 NCBI chr 2:82,442,645...82,453,332
Ensembl chr 2:82,441,891...82,453,485
JBrowse link
G Rpe65 retinoid isomerohydrolase RPE65 multiple interactions ISO [Iron-Dextran Complex results in increased abundance of Iron] which results in decreased expression of RPE65 mRNA; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in decreased expression of RPE65 mRNA] CTD PMID:33285147 NCBI chr 2:248,766,497...248,798,403
Ensembl chr 2:248,766,612...248,798,403
JBrowse link
G Rpl37 ribosomal protein L37 decreases expression ISO Iron results in decreased expression of RPL37 mRNA CTD PMID:27329587 NCBI chr10:61,033,799...61,034,157
Ensembl chr10:61,033,797...61,034,168
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 multiple interactions ISO [Iron co-treated with Oxygen] binds to RRM2 protein CTD PMID:16829694 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
JBrowse link
G RT1-Bb RT1 class II, locus Bb increases expression EXP Iron deficiency results in increased expression of RT1-BB mRNA CTD PMID:16629162 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 increases expression EXP Iron deficiency results in increased expression of RT1-DB1 mRNA CTD PMID:16629162 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G S100a9 S100 calcium binding protein A9 decreases expression EXP Iron deficiency results in decreased expression of S100A9 mRNA CTD PMID:16629162 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 increases expression
decreases expression
EXP Iron deficiency results in increased expression of SCD2 mRNA
Iron deficiency results in decreased expression of SCD2 mRNA
CTD PMID:16629162 PMID:19821111 NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232
JBrowse link
G Scp2 sterol carrier protein 2 decreases expression EXP Iron deficiency results in decreased expression of SCP2 mRNA CTD PMID:19821111 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
JBrowse link
G Sele selectin E multiple interactions ISO [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:12633744 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Serpinb8 serpin family B member 8 increases expression ISO Iron deficiency results in increased expression of SERPINB8 mRNA CTD PMID:20368581 NCBI chr13:23,626,945...23,650,270
Ensembl chr13:23,626,945...23,650,835
JBrowse link
G Sesn3 sestrin 3 decreases expression ISO Iron deficiency results in decreased expression of SESN3 mRNA CTD PMID:20368581 NCBI chr 8:11,133,822...11,189,436
Ensembl chr 8:11,133,678...11,185,842
JBrowse link
G Ska1 spindle and kinetochore associated complex subunit 1 increases expression ISO Iron deficiency results in increased expression of SKA1 mRNA CTD PMID:20368581 NCBI chr18:67,794,722...67,805,037
Ensembl chr18:67,794,725...67,805,037
JBrowse link
G Slc11a1 solute carrier family 11 member 1 multiple interactions ISO [CP gene mutant form results in increased abundance of Iron] which results in increased expression of SLC11A1 mRNA CTD PMID:16988052 NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101
JBrowse link
G Slc11a2 solute carrier family 11 member 2 multiple interactions
increases uptake
affects abundance
increases expression
increases transport
decreases expression
decreases uptake
affects metabolic processing
decreases transport
ISO
EXP
[Deferoxamine results in decreased abundance of Iron] which results in increased expression of SLC11A2 mRNA; [HFE protein binds to B2M protein binds to SLC11A2 protein] which results in decreased uptake of Iron; [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of SLC11A2 protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of SLC11A2 protein]; cupric chloride inhibits the reaction [SLC11A2 protein results in increased uptake of Iron]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of SLC11A2 protein]; Dronabinol inhibits the reaction [SLC11A2 protein results in increased uptake of Iron]; ebselen inhibits the reaction [SLC11A2 protein results in increased uptake of Iron]; prolinedithiocarbamate inhibits the reaction [SLC11A2 protein results in increased uptake of Iron]
SLC11A2 gene SNP affects the abundance of Iron
Iron deficiency results in increased expression of SLC11A2 mRNA; Iron results in increased expression of SLC11A2 mRNA; Iron results in increased expression of SLC11A2 protein
SLC11A2 protein alternative form results in increased uptake of Iron; SLC11A2 protein results in increased uptake of Iron
SLC11A2 protein results in increased transport of Iron
Iron results in decreased expression of SLC11A2 protein
SLC11A2 gene mutant form results in decreased uptake of Iron; SLC11A2 protein mutant form results in decreased uptake of Iron
SLC11A2 protein affects the metabolism of Iron
Iron deficiency results in increased expression of SLC11A2 mRNA; Iron deficiency results in increased expression of SLC11A2 protein; Iron results in increased expression of SLC11A2 mRNA; Iron results in increased expression of SLC11A2 protein
[Doxorubicin results in increased expression of SLC11A2 protein] which results in increased uptake of Iron; Iron inhibits the reaction [SLC11A2 protein results in increased uptake of manganese chloride]; Iron inhibits the reaction [SLC11A2 protein results in increased uptake of Manganese]; Manganese promotes the reaction [SLC11A2 protein results in increased transport of Iron]; Metals promotes the reaction [SLC11A2 protein results in increased transport of Iron]; Nitric Oxide promotes the reaction [[RASD1 protein binds to ACBD3 protein binds to SLC11A2 protein] which results in increased uptake of Iron]; SLC11A2 protein affects the reaction [Manganese results in increased transport of Iron]
SLC11A2 gene mutant form results in decreased transport of Iron
[Ethanol co-treated with Iron] results in increased expression of SLC11A2 mRNA; [Ethanol co-treated with Iron] results in increased expression of SLC11A2 protein; [SLC11A2 protein mutant form results in decreased phosphorylation of SLC11A2 protein] which results in decreased uptake of Iron; [Staurosporine results in decreased phosphorylation of SLC11A2 protein] which results in decreased uptake of Iron; Iron inhibits the reaction [Diethylnitrosamine results in decreased expression of SLC11A2 protein]; Quercetin inhibits the reaction [[Ethanol co-treated with Iron] results in increased expression of SLC11A2 mRNA]; Quercetin inhibits the reaction [[Ethanol co-treated with Iron] results in increased expression of SLC11A2 protein]; Quercetin inhibits the reaction [Iron results in increased expression of SLC11A2 mRNA]; Quercetin inhibits the reaction [Iron results in increased expression of SLC11A2 protein]
CTD PMID:11439223 PMID:12220667 PMID:12388109 PMID:12393473 PMID:15157939 More... NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
JBrowse link
G Slc12a2 solute carrier family 12 member 2 increases expression EXP Iron deficiency results in increased expression of SLC12A2 mRNA CTD PMID:16629162 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440
JBrowse link
G Slc23a2 solute carrier family 23 member 2 increases expression EXP Iron deficiency results in increased expression of SLC23A2 mRNA CTD PMID:16629162 NCBI chr 3:119,302,651...119,395,289
Ensembl chr 3:119,302,666...119,460,343
JBrowse link
G Slc26a11 solute carrier family 26 member 11 increases expression ISO Iron deficiency results in increased expression of SLC26A11 mRNA CTD PMID:20368581 NCBI chr10:104,613,498...104,635,873
Ensembl chr10:104,613,564...104,635,970
JBrowse link
G Slc2a5 solute carrier family 2 member 5 decreases expression ISO
EXP
Iron deficiency results in decreased expression of SLC2A5 mRNA CTD PMID:16629162 PMID:20368581 NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106
JBrowse link
G Slc34a2 solute carrier family 34 member 2 decreases expression EXP Iron deficiency results in decreased expression of SLC34A2 mRNA CTD PMID:16629162 NCBI chr14:57,910,931...57,930,236
Ensembl chr14:57,910,480...57,930,436
JBrowse link
G Slc39a14 solute carrier family 39 member 14 increases uptake
increases import
increases expression
multiple interactions
ISO SLC39A14 protein results in increased uptake of Iron
SLC39A14 protein results in increased import of Iron
Iron results in increased expression of SLC39A14 mRNA; Iron results in increased expression of SLC39A14 protein
4,7-diphenylphenanthroline sulfonate inhibits the reaction [SLC39A14 protein results in increased uptake of Iron]; [Ethanol co-treated with Iron] results in increased expression of SLC39A14 mRNA; [Ethanol co-treated with Iron] results in increased expression of SLC39A14 protein; Quercetin inhibits the reaction [[Ethanol co-treated with Iron] results in increased expression of SLC39A14 mRNA]; Quercetin inhibits the reaction [[Ethanol co-treated with Iron] results in increased expression of SLC39A14 protein]; Quercetin inhibits the reaction [Iron results in increased expression of SLC39A14 mRNA]; Quercetin inhibits the reaction [Iron results in increased expression of SLC39A14 protein]
CTD PMID:16950869 PMID:22898811 PMID:24569067 NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524
JBrowse link
G Slc39a8 solute carrier family 39 member 8 increases import
multiple interactions
ISO
EXP
SLC39A8 protein results in increased import of Iron
Cobalt inhibits the reaction [SLC39A8 protein results in increased import of Iron]; Iron inhibits the reaction [SLC39A8 protein results in increased import of Zinc]; Iron results in increased expression of and affects the localization of SLC39A8 protein; Manganese inhibits the reaction [SLC39A8 protein results in increased import of Iron]; Zinc inhibits the reaction [SLC39A8 protein results in increased import of Iron]
Protons affects the reaction [SLC39A8 protein results in increased import of Iron]
CTD PMID:22898811 NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129
JBrowse link
G Slc40a1 solute carrier family 40 member 1 multiple interactions
decreases expression
increases expression
increases export
decreases export
affects metabolic processing
ISO
EXP
[HBB-B1 gene mutant form results in increased abundance of Iron] which results in increased expression of SLC40A1 mRNA; [HBB-B2 gene mutant form results in increased abundance of Iron] which results in increased expression of SLC40A1 mRNA; [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of SLC40A1 mRNA; Iron inhibits the reaction [Diethylnitrosamine results in decreased expression of SLC40A1 mRNA]; Iron inhibits the reaction [Diethylnitrosamine results in decreased expression of SLC40A1 protein]; NFE2L2 protein promotes the reaction [SLC40A1 protein results in increased export of Iron]; SLC40A1 protein inhibits the reaction [ferrous sulfate results in increased uptake of Iron]
Iron results in decreased expression of SLC40A1 protein
Iron deficiency results in increased expression of SLC40A1 mRNA
[CP protein results in increased oxidation of Iron] which results in increased stability of SLC40A1 protein; Iron affects the reaction [HAMP protein results in increased uptake of SLC40A1 protein]; Iron inhibits the reaction [SLC40A1 protein results in increased export of Manganese]
SLC40A1 protein mutant form results in increased export of Iron; SLC40A1 protein results in increased export of Iron
SLC40A1 protein mutant form results in decreased export of Iron
SLC40A1 protein affects the metabolism of Iron
Iron deficiency results in increased expression of SLC40A1 mRNA; Iron results in increased expression of SLC40A1 mRNA
CTD PMID:16457665 PMID:16565419 PMID:16648237 PMID:17018382 PMID:17194590 More... NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
G Slc6a1 solute carrier family 6 member 1 multiple interactions
increases expression
decreases expression
EXP [Iron deficiency co-treated with manganese chloride] results in decreased expression of SLC6A1 mRNA; [Iron deficiency co-treated with manganese chloride] results in decreased expression of SLC6A1 protein; [Iron deficiency co-treated with manganese chloride] results in increased expression of SLC6A1 mRNA
Iron deficiency results in increased expression of SLC6A1 mRNA
Iron deficiency results in decreased expression of SLC6A1 protein
CTD PMID:18771689 NCBI chr 4:147,448,961...147,482,295
Ensembl chr 4:147,466,965...147,482,293
JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions EXP [manganese chloride co-treated with Iron deficiency] results in decreased expression of SLC6A3 protein CTD PMID:22479410 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor decreases expression ISO Iron deficiency results in decreased expression of SLPI mRNA CTD PMID:20368581 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
JBrowse link
G Smim3 small integral membrane protein 3 increases expression EXP Iron deficiency results in increased expression of SMIM3 mRNA CTD PMID:16629162 NCBI chr18:53,930,019...53,982,339
Ensembl chr18:53,930,020...53,957,416
JBrowse link
G Snapc1 small nuclear RNA activating complex, polypeptide 1 increases expression EXP Iron deficiency results in increased expression of SNAPC1 mRNA CTD PMID:16629162 NCBI chr 6:92,684,785...92,710,772
Ensembl chr 6:92,684,752...92,707,746
JBrowse link
G Snca synuclein alpha multiple interactions
increases response to substance
affects localization
ISO Cytarabine promotes the reaction [SNCA protein mutant form results in increased susceptibility to Iron]; Hydroxyurea promotes the reaction [SNCA protein mutant form results in increased susceptibility to Iron]; SNCA protein mutant form results in increased susceptibility to [Paraquat co-treated with Iron]
EUK-189 results in decreased susceptibility to [Iron co-treated with Paraquat co-treated with SNCA gene mutant form]
Iron affects the localization of SNCA protein
CTD PMID:12401952 PMID:14535945 PMID:21039522 PMID:27324791 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
affects abundance
ISO
EXP
SOD1 protein inhibits the reaction [Asbestos, Crocidolite results in increased uptake of Iron]
[Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of SOD1 protein]
SOD1 protein affects the abundance of Iron
[Corn Oil co-treated with Iron] results in decreased activity of SOD1 protein; Iron promotes the reaction [Corn Oil results in decreased activity of SOD1 protein]
CTD PMID:16272461 PMID:17194920 PMID:19482077 PMID:22534743 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
affects abundance
ISO
EXP
Deferoxamine inhibits the reaction [SOD2 protein affects the reaction [Ethanol results in increased abundance of Iron]]; SOD2 protein affects the reaction [Ethanol results in increased abundance of Iron]
[Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of SOD2 protein]
SOD2 protein polymorphism affects the abundance of Iron
Iron results in decreased expression of and results in decreased activity of SOD2 protein
CTD PMID:18760346 PMID:19063909 PMID:22534743 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sord sorbitol dehydrogenase affects abundance EXP SORD protein affects the abundance of Iron CTD PMID:18549825 NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133
JBrowse link
G Sort1 sortilin 1 increases expression ISO Iron deficiency results in increased expression of SORT1 mRNA CTD PMID:20368581 NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354
JBrowse link
G Sox9 SRY-box transcription factor 9 increases expression EXP Iron deficiency results in increased expression of SOX9 mRNA CTD PMID:16629162 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased activity of SP1 protein] CTD PMID:12633744 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
JBrowse link
G Sp6 Sp6 transcription factor increases expression EXP Iron deficiency results in increased expression of SP6 mRNA CTD PMID:16629162 NCBI chr10:82,005,518...82,009,699
Ensembl chr10:82,005,294...82,011,013
JBrowse link
G Spr sepiapterin reductase increases expression EXP Iron deficiency results in increased expression of SPR mRNA CTD PMID:16629162 NCBI chr 4:117,671,948...117,676,292
Ensembl chr 4:117,671,949...117,675,678
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO [Arsenic co-treated with Iron] results in increased expression of SQSTM1 mRNA; [Iron co-treated with Deferoxamine] results in increased expression of SQSTM1 protein; Iron affects the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone results in increased expression of SQSTM1 protein] CTD PMID:25301941 PMID:31739468 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO Iron promotes the reaction [Arsenic results in increased phosphorylation of and results in increased activity of SRC protein] CTD PMID:23100159 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Ssr1 signal sequence receptor subunit 1 multiple interactions ISO [Arsenic co-treated with Iron] results in decreased expression of SSR1 mRNA CTD PMID:31739468 NCBI chr17:26,833,720...26,861,821
Ensembl chr17:26,833,741...26,861,821
JBrowse link
G Steap2 STEAP2 metalloreductase increases reduction
increases uptake
ISO STEAP2 protein results in increased reduction of Iron
STEAP2 protein results in increased uptake of Iron
CTD PMID:16609065 NCBI chr 4:28,347,769...28,368,177
Ensembl chr 4:28,348,362...28,375,791
JBrowse link
G Steap3 STEAP3 metalloreductase affects metabolic processing
increases uptake
increases reduction
ISO STEAP3 protein affects the metabolism of Iron
STEAP3 protein results in increased uptake of Iron
STEAP3 protein results in increased reduction of Iron
CTD PMID:16609065 PMID:17194590 NCBI chr13:31,351,954...31,397,344
Ensembl chr13:31,351,954...31,396,519
JBrowse link
G Steap4 STEAP4 metalloreductase increases reduction
increases uptake
ISO STEAP4 protein results in increased reduction of Iron
STEAP4 protein results in increased uptake of Iron
CTD PMID:16609065 NCBI chr 4:26,077,182...26,099,859
Ensembl chr 4:26,054,671...26,099,859
JBrowse link
G Stk11 serine/threonine kinase 11 multiple interactions ISO STK11 protein affects the reaction [resveratrol results in decreased susceptibility to [Arachidonic Acid co-treated with Iron]] CTD PMID:19620254 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
JBrowse link
G Sulf2 sulfatase 2 increases expression ISO Iron deficiency results in increased expression of SULF2 mRNA CTD PMID:20368581 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415
JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 decreases expression ISO Iron deficiency results in decreased expression of TASL mRNA CTD PMID:20368581 NCBI chr  X:50,403,962...50,423,141
Ensembl chr  X:50,361,248...50,423,269
JBrowse link
G Tert telomerase reverse transcriptase increases activity EXP Iron results in increased activity of TERT protein CTD PMID:17189828 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tes testin LIM domain protein increases expression ISO Iron deficiency results in increased expression of TES mRNA CTD PMID:20368581 NCBI chr 4:45,365,304...45,403,829
Ensembl chr 4:45,365,285...45,403,829
JBrowse link
G Tf transferrin multiple interactions
affects binding
increases expression
increases uptake
affects metabolic processing
ISO
EXP
[Aluminum binds to TF protein] which results in decreased uptake of Iron; [Iron binds to TF protein] which results in decreased uptake of Iron; [TF protein binds to Aluminum] affects the activity of [TF protein binds to Iron]; [TF protein binds to Aluminum] which results in increased uptake of Iron; ammonium ferric sulfate promotes the reaction [TF protein results in increased uptake of Iron]; cobaltous chloride inhibits the reaction [TF protein results in increased uptake of Iron]; cuprous chloride inhibits the reaction [TF protein results in increased uptake of Iron]; ferric ammonium citrate inhibits the reaction [TF protein results in increased uptake of Iron]; ferric chloride promotes the reaction [TF protein results in increased uptake of Iron]; ferrous sulfate promotes the reaction [TF protein results in increased uptake of Iron]; gallium nitrate promotes the reaction [TF protein results in increased uptake of Iron]; TF protein binds to [Aluminum co-treated with Iron]; TF protein binds to and affects the transport of Iron; zinc chloride inhibits the reaction [TF protein results in increased uptake of Iron]
[Iron binds to TF protein] which binds to TFRC protein; [TF protein binds to Iron] which binds to TFRC protein; CP protein binds to [TF protein binds to Iron]; Iron binds to TF protein; TF protein binds to Iron
Iron deficiency results in increased expression of TF protein
[Iron deficiency co-treated with Manganese] results in increased expression of TF protein; [Melatonin results in increased expression of TF protein] which affects the abundance of Iron; [S-Adenosylmethionine results in increased expression of TF protein] which affects the abundance of Iron; Copper deficiency results in decreased expression of [Iron binds to TF protein]
TRF protein affects the metabolism of Iron
CTD PMID:2039817 PMID:2308257 PMID:8782865 PMID:11193083 PMID:11335103 More... NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tff1 trefoil factor 1 increases expression EXP Iron deficiency results in increased expression of TFF1 mRNA CTD PMID:16629162 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
JBrowse link
G Tfr2 transferrin receptor 2 multiple interactions
decreases expression
affects metabolic processing
increases uptake
affects response to substance
ISO
EXP
[HBB-B1 gene mutant form results in increased abundance of Iron] which results in decreased expression of TFR2 mRNA; [HBB-B2 gene mutant form results in increased abundance of Iron] which results in decreased expression of TFR2 mRNA; [HFE gene mutant form co-treated with TFR2 gene mutant form] results in increased abundance of Iron; Iron inhibits the reaction [Diethylnitrosamine results in decreased expression of TFR2 protein]
Iron deficiency results in decreased expression of TFR2 protein
TFR2 protein affects the metabolism of Iron
TFR2 protein mutant form results in increased uptake of Iron
TFR2 protein affects the susceptibility to Iron
[HFE protein binds to TFR2 protein] which affects the susceptibility to Iron
CTD PMID:16893896 PMID:16935854 PMID:17018382 PMID:17194590 PMID:17241880 More... NCBI chr12:19,107,673...19,124,622
Ensembl chr12:19,107,673...19,124,591
JBrowse link
G Tfrc transferrin receptor increases expression
affects binding
decreases expression
increases uptake
multiple interactions
affects expression
affects metabolic processing
ISO
EXP
Iron results in increased expression of TFRC protein
Iron deficiency results in increased expression of TFRC mRNA; Iron results in increased expression of TFRC mRNA
[Iron binds to TF protein] which binds to TFRC protein; [TF protein binds to Iron] which binds to TFRC protein
Iron deficiency results in increased expression of TFRC mRNA; Iron deficiency results in increased expression of TFRC protein
Iron results in decreased expression of TFRC mRNA
TFRC protein results in increased uptake of Iron
[Iron co-treated with Diethylnitrosamine co-treated with Copper] results in decreased expression of TFRC mRNA; [Iron co-treated with Diethylnitrosamine] results in decreased expression of TFRC mRNA; [Iron co-treated with Diethylnitrosamine] results in decreased expression of TFRC protein; Clofibrate inhibits the reaction [Iron deficiency results in increased expression of TFRC mRNA]
Iron affects the expression of TFRC mRNA; Iron affects the expression of TFRC protein
TFRC protein affects the metabolism of Iron
[CP gene mutant form results in increased abundance of Iron] which results in decreased expression of TFRC mRNA; [Iron co-treated with Ethanol] results in increased expression of TFRC mRNA; [Zinc deficiency results in increased abundance of Iron] which results in increased expression of TFRC mRNA; [Zinc deficiency results in increased abundance of Iron] which results in increased expression of TFRC protein; Iron inhibits the reaction [Diethylnitrosamine results in increased expression of TFRC protein]; Quercetin inhibits the reaction [[Iron co-treated with Ethanol] results in increased expression of TFRC mRNA]; Quercetin inhibits the reaction [Iron results in increased expression of TFRC mRNA]
[Deferoxamine results in decreased abundance of Iron] which results in increased expression of TFRC mRNA; [ferric ammonium citrate results in decreased abundance of Iron] which results in increased expression of TFRC mRNA; [Fluvastatin results in decreased expression of TFRC protein] which results in decreased uptake of Iron; [GGTI 298 results in decreased expression of TFRC protein] which results in decreased uptake of Iron; [Hemin results in decreased abundance of Iron] which results in increased expression of TFRC mRNA; [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TFRC protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TFRC protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TFRC protein]; HFE protein inhibits the reaction [TFRC protein results in increased uptake of Iron]
CTD PMID:10085150 PMID:11068183 PMID:11969379 PMID:12393473 PMID:16428268 More... NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP Iron promotes the reaction [Asbestos, Amosite results in increased expression of TGFB1 mRNA] CTD PMID:11306436 PMID:12475806 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 multiple interactions ISO [Arsenic co-treated with Iron] results in increased expression of TGFBR1 mRNA CTD PMID:31739468 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 increases expression EXP Iron deficiency results in increased expression of TGIF1 mRNA CTD PMID:16629162 NCBI chr 9:110,748,094...110,757,714
Ensembl chr 9:110,720,921...110,757,802
JBrowse link
G Tmem154 transmembrane protein 154 increases expression ISO Iron deficiency results in increased expression of TMEM154 mRNA CTD PMID:20368581 NCBI chr 2:169,947,534...170,054,901
Ensembl chr 2:170,015,184...170,052,481
JBrowse link
G Tmem252 transmembrane protein 252 increases expression EXP Iron deficiency results in increased expression of TMEM252 mRNA CTD PMID:16629162 NCBI chr 1:222,316,982...222,321,946
Ensembl chr 1:222,316,795...222,321,943
JBrowse link
G Tmem45b transmembrane protein 45b decreases expression EXP Iron deficiency results in decreased expression of TMEM45B mRNA CTD PMID:16629162 NCBI chr 8:29,865,276...29,910,453
Ensembl chr 8:29,865,278...29,910,453
JBrowse link
G Tmem86a transmembrane protein 86A increases expression EXP Iron deficiency results in increased expression of TMEM86A mRNA CTD PMID:16629162 NCBI chr 1:97,595,910...97,600,260
Ensembl chr 1:97,595,842...97,600,260
JBrowse link
G Tmprss6 transmembrane serine protease 6 affects abundance ISO TMPRSS6 gene SNP affects the abundance of Iron CTD PMID:19820698 PMID:19820699 NCBI chr 7:109,991,008...110,021,626
Ensembl chr 7:109,985,931...110,021,624
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases uptake
decreases abundance
increases secretion
increases expression
EXP
ISO
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Iron results in increased secretion of TNF protein]; [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TNF protein; [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of TNF protein; Ergothioneine inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TNF protein]; lipopolysaccharide A promotes the reaction [Iron results in increased secretion of TNF protein]; MAP3K14 protein affects the reaction [Iron results in increased secretion of TNF protein]; MAP3K7 protein affects the reaction [Iron results in increased secretion of TNF protein]; PIK3R1 protein affects the reaction [Iron results in increased secretion of TNF protein]; taxifolin inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TNF protein]; TNF protein affects the transport of and results in decreased abundance of Iron; U 0126 inhibits the reaction [Iron results in increased secretion of TNF protein]
[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TNF protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TNF protein]
TNF protein results in increased uptake of Iron
TNF protein results in decreased abundance of Iron
Iron results in increased expression of TNF mRNA
[Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased activity of SP1 protein]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of SELE protein]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; TNF gene SNP promotes the reaction [HFE protein mutant form results in increased uptake of Iron]
CTD PMID:10865941 PMID:12633744 PMID:16566752 PMID:16793930 PMID:16890145 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfsf10 TNF superfamily member 10 increases expression ISO Iron deficiency results in increased expression of TNFSF10 mRNA CTD PMID:20368581 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tppp3 tubulin polymerization-promoting protein family member 3 increases expression EXP Iron deficiency results in increased expression of TPPP3 mRNA CTD PMID:16629162 NCBI chr19:33,345,897...33,349,610
Ensembl chr19:33,345,898...33,349,577
JBrowse link
G Treml2 triggering receptor expressed on myeloid cells-like 2 increases expression ISO Iron deficiency results in increased expression of TREML2 mRNA CTD PMID:20368581 NCBI chr 9:12,694,453...12,705,379
Ensembl chr 9:12,694,697...12,705,324
JBrowse link
G Trim27 tripartite motif-containing 27 increases expression EXP Iron deficiency results in increased expression of TRIM27 mRNA CTD PMID:16629162 NCBI chr17:43,538,282...43,550,633
Ensembl chr17:43,538,285...43,550,643
JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 increases uptake ISO TRPC6 protein results in increased uptake of Iron CTD PMID:14640978 NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092
JBrowse link
G Tshz1 teashirt zinc finger homeobox 1 increases expression EXP Iron deficiency results in increased expression of TSHZ1 mRNA CTD PMID:16629162 NCBI chr18:77,376,399...77,452,315
Ensembl chr18:77,377,394...77,453,509
JBrowse link
G Tshz3 teashirt zinc finger homeobox 3 increases expression ISO Iron deficiency results in increased expression of TSHZ3 mRNA CTD PMID:20368581 NCBI chr 1:89,386,732...89,460,719
Ensembl chr 1:89,381,858...89,460,874
JBrowse link
G Txn2 thioredoxin 2 multiple interactions ISO [3-aminopyridine-2-carboxaldehyde thiosemicarbazone binds to Iron] which results in increased oxidation of TXN2 protein CTD PMID:21195754 NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359
JBrowse link
G Txnip thioredoxin interacting protein multiple interactions ISO [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TXNIP mRNA; [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TXNIP protein CTD PMID:33393188 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO [Iron-Dextran Complex results in increased abundance of Iron] which results in decreased expression of TXNRD1 mRNA; [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TXNRD1 protein CTD PMID:33393188 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Ube2e1 ubiquitin-conjugating enzyme E2E 1 decreases expression ISO Iron deficiency results in decreased expression of UBE2E1 mRNA CTD PMID:20368581 NCBI chr15:7,439,502...7,493,410
Ensembl chr15:7,439,759...7,493,400
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 multiple interactions EXP [Nickel co-treated with Iron co-treated with Tungsten] results in decreased expression of UGT1A6 mRNA CTD PMID:22198552 NCBI chr 9:88,747,229...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt2b15 UDP glucuronosyltransferase family 2 member B15 decreases expression EXP Iron deficiency results in decreased expression of UGT2B15 mRNA CTD PMID:16629162 NCBI chr14:20,768,015...20,783,599
Ensembl chr14:20,768,015...20,783,589
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 decreases expression EXP Iron deficiency results in decreased expression of UGT2B17 mRNA CTD PMID:16629162 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
G Urod uroporphyrinogen decarboxylase decreases activity
multiple interactions
ISO
EXP
Iron results in decreased activity of UROD protein
Iron inhibits the reaction [Ethinyl Estradiol results in increased activity of UROD protein]
CTD PMID:3945969 PMID:12030801 NCBI chr 5:130,464,695...130,468,783
Ensembl chr 5:130,455,217...130,468,808
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] CTD PMID:12633744 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vdr vitamin D receptor increases expression ISO Iron deficiency results in increased expression of VDR mRNA CTD PMID:20368581 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
G Vsig10l V-set and immunoglobulin domain containing 10 like decreases expression EXP Iron deficiency results in decreased expression of VSIG10L mRNA CTD PMID:16629162 NCBI chr 1:93,871,487...93,880,157
Ensembl chr 1:93,851,774...93,879,566
JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 increases expression ISO Iron deficiency results in increased expression of WIPI1 mRNA CTD PMID:20368581 NCBI chr10:94,542,946...94,580,174
Ensembl chr10:94,542,946...94,579,846
JBrowse link
G Zfp503 zinc finger protein 503 increases expression EXP Iron deficiency results in increased expression of ZFP503 mRNA CTD PMID:16629162 NCBI chr15:2,313,060...2,316,848
Ensembl chr15:2,313,060...2,316,848
JBrowse link
ferbam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100125598 metallothionein 1a pseudogene increases expression ISO ferbam results in increased expression of MT1G mRNA CTD PMID:32870474 NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases activity ISO ferbam results in decreased activity of TGFB1 protein CTD PMID:31652400 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
ferric ammonium citrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 increases activity
decreases activity
ISO ferric ammonium citrate results in increased activity of ACO1 protein
ferric ammonium citrate results in decreased activity of ACO1 protein
CTD PMID:11054110 PMID:18073202 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Aco2 aconitase 2 multiple interactions
increases activity
ISO ferric ammonium citrate inhibits the reaction [manganese chloride results in decreased activity of ACO2 protein]; ferric ammonium citrate inhibits the reaction [Manganese results in decreased activity of ACO2 protein]
ferric ammonium citrate results in increased activity of ACO2 protein
CTD PMID:16625280 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]] CTD PMID:32283200 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alb albumin multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of ALB protein] CTD PMID:24862973 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Anxa3 annexin A3 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ANXA3 protein] CTD PMID:19515424 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ARHGDIA protein] CTD PMID:19515424 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO ferric ammonium citrate affects the reaction [Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]]; ferric ammonium citrate inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA] CTD PMID:25633564 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
ISO ferric ammonium citrate results in increased cleavage of CASP3 protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; Deferoxamine inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; DNM1L protein mutant form inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]
CTD PMID:17191120 PMID:26318285 PMID:27481217 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO ferric ammonium citrate inhibits the reaction [2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CDKN1A protein] CTD PMID:12807743 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO ferric ammonium citrate results in decreased expression of COL1A1 mRNA CTD PMID:19735707 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Dnm1l dynamin 1-like multiple interactions
decreases phosphorylation
ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; Cyclosporine inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; Deferoxamine inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; DNM1L protein mutant form inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; ferric ammonium citrate results in decreased phosphorylation of and affects the localization of DNM1L protein; N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; Tacrolimus inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein] CTD PMID:26318285 PMID:27481217 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:32283200 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Erp29 endoplasmic reticulum protein 29 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ERP29 protein] CTD PMID:19515424 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
JBrowse link
G F3 coagulation factor III, tissue factor increases expression
multiple interactions
ISO ferric ammonium citrate results in increased expression of F3 mRNA
Deferoxamine inhibits the reaction [ferric ammonium citrate results in increased expression of F3 mRNA]
CTD PMID:25858758 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO ferric ammonium citrate promotes the reaction [Palmitic Acid results in increased expression of FTH1 protein] CTD PMID:32283200 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Ftl1 ferritin light chain 1 multiple interactions
increases expression
ISO [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of FTL mRNA
ferric ammonium citrate results in increased expression of FTL1 mRNA
SLC40A1 protein inhibits the reaction [ferric ammonium citrate results in increased expression of FTL1 mRNA]
CTD PMID:12393473 PMID:19913091 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of GAPDH protein] CTD PMID:19515424 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Glo1 glyoxalase 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of GLO1 protein] CTD PMID:19515424 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions
decreases expression
ISO Deferoxamine promotes the reaction [ferric ammonium citrate results in decreased expression of HAMP mRNA]; ferric ammonium citrate affects the reaction [Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]]; ferric ammonium citrate inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA] CTD PMID:25633564 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
EXP
ISO
ferric ammonium citrate results in increased expression of HMOX1 protein
[ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of HMOX1 mRNA
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [ferric ammonium citrate results in increased expression of HMOX1 protein]
CTD PMID:12393473 PMID:16439612 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of HSPA1A protein] CTD PMID:19515424
G Hspa1l heat shock protein family A (Hsp70) member 1 like multiple interactions ISO [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of HSPA1L mRNA CTD PMID:12393473 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 multiple interactions ISO [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of HSPA9 mRNA CTD PMID:12393473 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of HSPD1 protein] CTD PMID:19515424 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of IL1B protein] CTD PMID:24862973 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of IL6 mRNA]; ferric ammonium citrate inhibits the reaction [Ozone results in increased secretion of IL6 protein] CTD PMID:24862973 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins2 insulin 2 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; Thapsigargin inhibits the reaction [ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]] CTD PMID:32283200 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Ireb2 iron responsive element binding protein 2 decreases expression
decreases activity
EXP
ISO
ferric ammonium citrate results in decreased expression of IREB2 protein
ferric ammonium citrate results in decreased activity of IREB2 protein
CTD PMID:11054110 PMID:17469137 PMID:18073202 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
JBrowse link
G Lcn2 lipocalin 2 multiple interactions ISO ferric ammonium citrate inhibits the reaction [bathophenanthroline disulfonic acid results in decreased expression of LCN2 protein] CTD PMID:17350462 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO [ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in decreased phosphorylation of MAPK1 protein
ferric ammonium citrate results in increased phosphorylation of MAPK1 protein
CTD PMID:17191120 PMID:25858758 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation ISO ferric ammonium citrate results in increased phosphorylation of MAPK14 protein CTD PMID:17191120 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO [ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in decreased phosphorylation of MAPK3 protein
ferric ammonium citrate results in increased phosphorylation of MAPK3 protein
CTD PMID:17191120 PMID:25858758 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mrps9 mitochondrial ribosomal protein S9 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of MRPS9 protein] CTD PMID:19515424 NCBI chr 9:45,113,554...45,172,375
Ensembl chr 9:45,113,554...45,172,375
JBrowse link
G Mt2A metallothionein 2A multiple interactions ISO [ferric ammonium citrate results in decreased abundance of Iron] which results in increased expression of MT2A mRNA CTD PMID:12393473 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Ncoa4 nuclear receptor coactivator 4 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased expression of NCOA4 protein] CTD PMID:32283200 NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,366,542...7,409,556
Ensembl chr16:7,366,542...7,409,556
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO [ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in increased expression of NOS2 mRNA; Acetylcysteine inhibits the reaction [[ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in increased expression of NOS2 mRNA] CTD PMID:9826428 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Oga O-GlcNAcase multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of OGA protein] CTD PMID:24862973 NCBI chr 1:244,598,285...244,633,835
Ensembl chr 1:244,598,292...244,634,359
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of P4HA1 protein] CTD PMID:19515424 NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PDHB protein] CTD PMID:19515424 NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PGK1 protein] CTD PMID:19515424 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Pmp22 peripheral myelin protein 22 multiple interactions ISO [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of PMP22 mRNA CTD PMID:12393473 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
JBrowse link
G Ppia peptidylprolyl isomerase A multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PPIA protein] CTD PMID:19515424 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of PTGS2 mRNA] CTD PMID:24862973 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rack1 receptor for activated C kinase 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of RACK1 protein] CTD PMID:19515424 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975
JBrowse link
G Slc11a1 solute carrier family 11 member 1 increases expression ISO ferric ammonium citrate results in increased expression of SLC11A1 mRNA CTD PMID:11054110 NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101
JBrowse link
G Slc11a2 solute carrier family 11 member 2 increases expression ISO ferric ammonium citrate results in increased expression of SLC11A2 mRNA CTD PMID:11054110 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
JBrowse link
G Slc40a1 solute carrier family 40 member 1 increases expression
multiple interactions
EXP
ISO
ferric ammonium citrate results in increased expression of SLC40A1 mRNA
SLC40A1 protein inhibits the reaction [ferric ammonium citrate results in increased expression of FTL1 mRNA]
CTD PMID:19913091 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of SOD1 mRNA] CTD PMID:24862973 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Tf transferrin multiple interactions ISO ferric ammonium citrate inhibits the reaction [TF protein results in increased uptake of Iron] CTD PMID:11335103 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tfr2 transferrin receptor 2 decreases expression ISO ferric ammonium citrate results in decreased expression of TFR2 protein CTD PMID:25633564 NCBI chr12:19,107,673...19,124,622
Ensembl chr12:19,107,673...19,124,591
JBrowse link
G Tfrc transferrin receptor decreases expression
multiple interactions
ISO ferric ammonium citrate results in decreased expression of TFRC mRNA; ferric ammonium citrate results in decreased expression of TFRC protein
[ferric ammonium citrate results in decreased abundance of Iron] which results in increased expression of TFRC mRNA
CTD PMID:11054110 PMID:12393473 PMID:16760464 PMID:18073202 PMID:25633564 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of TNF protein] CTD PMID:24862973 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tpd52l1 TPD52 like 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of TPD52L1 protein] CTD PMID:19515424 NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109
JBrowse link
G Vdac2 voltage-dependent anion channel 2 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of VDAC2 protein] CTD PMID:19515424 NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased expression of XBP1 protein] CTD PMID:32283200 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
ferric oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatk apoptosis-associated tyrosine kinase increases expression ISO ferric oxide analog results in increased expression of AATK mRNA CTD PMID:25086211 NCBI chr10:105,290,750...105,327,219
Ensembl chr10:105,291,585...105,327,112
JBrowse link
G Ache acetylcholinesterase decreases activity ISO ferric oxide results in decreased activity of ACHE protein CTD PMID:28993115 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 increases expression ISO ferric oxide analog results in increased expression of ACSS2 mRNA CTD PMID:25086211 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 increases expression ISO ferric oxide analog results in increased expression of ADGRE1 mRNA CTD PMID:24525745 NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000
JBrowse link
G Adm adrenomedullin increases expression ISO ferric oxide analog results in increased expression of ADM mRNA CTD PMID:25086211 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Adora2b adenosine A2B receptor increases expression ISO ferric oxide analog results in increased expression of ADORA2B mRNA CTD PMID:25086211 NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
JBrowse link
G Ahnak2 AHNAK nucleoprotein 2 increases expression ISO ferric oxide analog results in increased expression of AHNAK2 mRNA CTD PMID:25086211 NCBI chr 6:131,830,668...131,876,311 JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor increases expression ISO ferric oxide analog results in increased expression of AHRR mRNA CTD PMID:24525745 NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673
JBrowse link
G Aig1 androgen-induced 1 increases expression ISO ferric oxide analog results in increased expression of AIG1 mRNA CTD PMID:25086211 NCBI chr 1:8,046,430...8,269,276
Ensembl chr 1:8,046,430...8,269,084
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP [ferric oxide analog co-treated with Acrolein] results in increased phosphorylation of AKT1 protein CTD PMID:24847785 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 decreases expression ISO ferric oxide analog results in decreased expression of ALDH1L2 mRNA CTD PMID:25086211 NCBI chr 7:20,254,196...20,305,793
Ensembl chr 7:20,254,233...20,305,776
JBrowse link
G Ankrd12 ankyrin repeat domain 12 decreases expression ISO ferric oxide analog results in decreased expression of ANKRD12 mRNA CTD PMID:24525745 NCBI chr 9:105,583,273...105,687,957
Ensembl chr 9:105,584,065...105,687,911
JBrowse link
G Anln anillin, actin binding protein decreases expression
increases expression
ISO ferric oxide analog results in decreased expression of ANLN mRNA
ferric oxide analog results in increased expression of ANLN mRNA
CTD PMID:24525745 PMID:25086211 NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538
JBrowse link
G Anxa3 annexin A3 decreases expression ISO ferric oxide analog results in decreased expression of ANXA3 mRNA CTD PMID:25086211 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
JBrowse link
G Ap5b1 adaptor related protein complex 5 subunit beta 1 decreases expression ISO ferric oxide analog results in decreased expression of AP5B1 mRNA CTD PMID:25086211 NCBI chr 1:202,876,272...202,880,303
Ensembl chr 1:202,876,272...202,880,289
JBrowse link
G Arhgap24 Rho GTPase activating protein 24 increases expression ISO ferric oxide analog results in increased expression of ARHGAP24 mRNA CTD PMID:25086211 NCBI chr14:6,800,631...7,184,001
Ensembl chr14:6,800,631...7,183,823
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO ferric oxide analog results in increased expression of ATF3 protein CTD PMID:24068039 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atg5 autophagy related 5 increases expression ISO ferric oxide analog results in increased expression of ATG5 protein CTD PMID:24068039 NCBI chr20:47,798,222...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G B3galnt1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) increases expression ISO ferric oxide analog results in increased expression of B3GALNT1 mRNA CTD PMID:24525745 NCBI chr 2:153,847,297...153,877,371
Ensembl chr 2:153,846,474...153,877,332
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
decreases expression
increases phosphorylation
ISO
EXP
bromotetrandrine promotes the reaction [[ferric oxide co-treated with ferrous oxide co-treated with Daunorubicin] results in increased expression of BAX protein]
ferric oxide results in increased expression of BAX protein
ferric oxide results in decreased expression of BAX protein
ferric oxide analog results in increased phosphorylation of BAX protein
CTD PMID:19421372 PMID:22995439 PMID:25086211 PMID:26991130 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases phosphorylation
increases expression
EXP
ISO
ferric oxide analog results in increased phosphorylation of BCL2 protein
ferric oxide analog results in increased expression of BCL2 protein
CTD PMID:22995439 PMID:25086211 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l11 BCL2 like 11 increases expression ISO ferric oxide analog results in increased expression of BCL2L11 mRNA; ferric oxide analog results in increased expression of BCL2L11 protein CTD PMID:24525745 PMID:25086211 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bdh2 3-hydroxybutyrate dehydrogenase 2 increases expression ISO ferric oxide analog results in increased expression of BDH2 mRNA CTD PMID:25086211 NCBI chr 2:223,702,410...223,723,076
Ensembl chr 2:223,702,412...223,723,072
JBrowse link
G Becn1 beclin 1 decreases expression
increases expression
ISO ferric oxide results in decreased expression of BECN1 protein
ferric oxide analog results in increased expression of BECN1 protein
CTD PMID:24068039 PMID:25086211 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression ISO ferric oxide analog results in increased expression of BHLHE40 mRNA CTD PMID:25086211 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
JBrowse link
G Canx calnexin decreases expression ISO ferric oxide results in decreased expression of CANX protein CTD PMID:25086211 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
ISO bromotetrandrine promotes the reaction [[ferric oxide co-treated with ferrous oxide co-treated with Daunorubicin] results in increased expression of CASP3 protein]
ferric oxide results in increased cleavage of CASP3 protein
CTD PMID:19421372 PMID:26991130 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 increases expression ISO ferric oxide analog results in increased expression of CASTOR1 mRNA CTD PMID:25086211 NCBI chr14:79,086,136...79,090,549
Ensembl chr14:79,086,136...79,090,548
JBrowse link
G Cat catalase decreases activity
decreases expression
ISO ferric oxide results in decreased activity of CAT protein
ferric oxide results in decreased expression of CAT protein
CTD PMID:19699289 PMID:26991130 PMID:28993115 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccdc85b coiled-coil domain containing 85B increases expression ISO ferric oxide analog results in increased expression of CCDC85B mRNA CTD PMID:25086211 NCBI chr 1:202,763,645...202,764,631
Ensembl chr 1:202,763,631...202,764,703
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases secretion ISO ferric oxide results in increased secretion of CCL2 protein CTD PMID:24885771 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 increases secretion ISO ferric oxide results in increased secretion of CCL22 protein CTD PMID:24885771 NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases secretion ISO ferric oxide results in increased secretion of CCL3 protein CTD PMID:24885771 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression
increases secretion
ISO ferric oxide analog results in decreased expression of CCL4 mRNA
ferric oxide results in increased secretion of CCL4 protein
CTD PMID:24525745 PMID:24885771 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases secretion ISO ferric oxide results in increased secretion of CCL7 protein CTD PMID:24885771 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Cd14 CD14 molecule decreases expression ISO ferric oxide analog results in decreased expression of CD14 mRNA CTD PMID:25086211 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd274 CD274 molecule increases expression ISO ferric oxide analog results in increased expression of CD274 mRNA CTD PMID:25086211 NCBI chr 1:227,116,627...227,137,379
Ensembl chr 1:227,116,649...227,134,450
JBrowse link
G Cd74 CD74 molecule decreases expression ISO ferric oxide analog results in decreased expression of CD74 mRNA CTD PMID:25086211 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Cd83 CD83 molecule increases expression ISO ferric oxide analog results in increased expression of CD83 mRNA CTD PMID:24525745 PMID:25086211 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP ferric oxide analog results in increased expression of CDKN1A protein CTD PMID:22995439 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions EXP [ferric oxide analog co-treated with Acrolein] results in decreased expression of CDKN1B protein CTD PMID:24847785 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A decreases expression ISO ferric oxide analog results in decreased expression of CDKN2A mRNA CTD PMID:24525745 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cep83 centrosomal protein 83 decreases expression ISO ferric oxide analog results in decreased expression of CEP83 mRNA CTD PMID:24525745 NCBI chr 7:29,280,358...29,389,574
Ensembl chr 7:29,280,419...29,389,574
JBrowse link
G Clec5a C-type lectin domain containing 5A decreases expression ISO ferric oxide analog results in decreased expression of CLEC5A mRNA CTD PMID:25086211 NCBI chr 4:69,407,125...69,416,872
Ensembl chr 4:69,407,835...69,416,859
JBrowse link
G Clk4 CDC-like kinase 4 increases expression ISO ferric oxide analog results in increased expression of CLK4 mRNA CTD PMID:25086211 NCBI chr10:35,523,382...35,541,387
Ensembl chr10:35,524,755...35,541,352
JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 decreases expression ISO ferric oxide analog results in decreased expression of COX6A2 mRNA CTD PMID:25086211 NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274
JBrowse link
G Csnk1e casein kinase 1, epsilon increases expression ISO ferric oxide analog results in increased expression of CSNK1E mRNA CTD PMID:25086211 NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 decreases expression ISO ferric oxide analog results in decreased expression of CX3CR1 mRNA CTD PMID:25086211 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO ferric oxide analog results in increased expression of CXCR4 mRNA CTD PMID:25086211 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP ferric oxide promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A1 protein]; ferric oxide promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA] CTD PMID:15211619 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
decreases expression
ISO ferric oxide analog results in increased expression of DDIT3 mRNA; ferric oxide analog results in increased expression of DDIT3 protein
ferric oxide analog results in decreased expression of DDIT3 mRNA
CTD PMID:24525745 PMID:25086211 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 decreases expression ISO ferric oxide analog results in decreased expression of DDIT4 mRNA CTD PMID:24525745 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Dgkg diacylglycerol kinase, gamma decreases expression ISO ferric oxide analog results in decreased expression of DGKG mRNA CTD PMID:25086211 NCBI chr11:78,384,212...78,579,158
Ensembl chr11:78,384,458...78,577,212
JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression ISO ferric oxide analog results in decreased expression of DUSP1 mRNA CTD PMID:25086211 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp4 dual specificity phosphatase 4 increases expression ISO ferric oxide analog results in increased expression of DUSP4 mRNA CTD PMID:25086211 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 decreases expression ISO ferric oxide analog results in decreased expression of EEF1A1 mRNA CTD PMID:25086211 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
JBrowse link
G Egfr epidermal growth factor receptor increases phosphorylation ISO ferric oxide analog results in increased phosphorylation of EGFR protein CTD PMID:24068039 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 decreases expression ISO ferric oxide analog results in decreased expression of EGR1 mRNA CTD PMID:25086211 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Egr2 early growth response 2 increases expression ISO ferric oxide analog results in increased expression of EGR2 mRNA CTD PMID:24525745 PMID:25086211 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 decreases expression ISO ferric oxide analog results in decreased expression of EIF2AK2 mRNA CTD PMID:25086211 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
JBrowse link
G Eno2 enolase 2 increases expression
decreases expression
ISO ferric oxide analog results in increased expression of ENO2 mRNA
ferric oxide analog results in decreased expression of ENO2 mRNA
CTD PMID:24525745 PMID:25086211 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Epn2 epsin 2 increases expression ISO ferric oxide analog results in increased expression of EPN2 mRNA CTD PMID:25086211 NCBI chr10:46,197,785...46,259,673
Ensembl chr10:46,197,785...46,259,642
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO ferric oxide analog results in increased expression of and results in increased phosphorylation of ERN1 protein CTD PMID:25086211 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Fam214a family with sequence similarity 214, member A increases expression ISO ferric oxide analog results in increased expression of FAM214A mRNA CTD PMID:25086211 NCBI chr 8:75,694,828...75,772,565
Ensembl chr 8:75,695,022...75,772,549
JBrowse link
G Fblim1 filamin binding LIM protein 1 increases expression ISO ferric oxide analog results in increased expression of FBLIM1 mRNA CTD PMID:25086211 NCBI chr 5:153,883,946...153,915,524
Ensembl chr 5:153,883,960...153,913,757
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression
increases expression
ISO ferric oxide analog results in decreased expression of FOS mRNA
ferric oxide analog results in increased expression of FOS mRNA
CTD PMID:24525745 PMID:25086211 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fus FUS RNA binding protein decreases expression ISO ferric oxide analog results in decreased expression of FUS mRNA CTD PMID:25086211 NCBI chr 1:182,576,479...182,590,417
Ensembl chr 1:182,576,545...182,590,414
JBrowse link
G Fyb1 FYN binding protein 1 decreases expression ISO ferric oxide analog results in decreased expression of FYB mRNA CTD PMID:25086211 NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases phosphorylation EXP ferric oxide analog results in increased phosphorylation of GADD45A protein CTD PMID:22995439 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression ISO ferric oxide analog results in increased expression of GADD45B mRNA CTD PMID:25086211 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression ISO ferric oxide analog results in increased expression of GJA1 mRNA CTD PMID:25086211 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gpr183 G protein-coupled receptor 183 increases expression ISO ferric oxide analog results in increased expression of GPR183 mRNA CTD PMID:24525745 NCBI chr15:99,037,764...99,050,550
Ensembl chr15:99,036,367...99,050,559
JBrowse link
G Gpr84 G protein-coupled receptor 84 decreases expression
increases expression
ISO ferric oxide analog results in decreased expression of GPR84 mRNA
ferric oxide analog results in increased expression of GPR84 mRNA
CTD PMID:24525745 PMID:25086211 NCBI chr 7:134,443,904...134,446,173
Ensembl chr 7:134,443,936...134,446,178
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO [Benzo(a)pyrene co-treated with ferric oxide] results in increased activity of GSR protein CTD PMID:11033230 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases expression
ISO Oxygen deficiency inhibits the reaction [ferric oxide analog results in increased expression of H2AX protein] CTD PMID:27270449 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G H2bc9 H2B clustered histone 9 decreases expression ISO ferric oxide analog results in decreased expression of H2BC9 mRNA CTD PMID:24525745 PMID:25086211 NCBI chr17:42,470,593...42,478,605 JBrowse link
G H2bu1 H2B.U histone 1 increases expression ISO ferric oxide analog results in increased expression of H2BC21 mRNA CTD PMID:25086211 NCBI chr10:43,732,737...43,733,484
Ensembl chr10:43,732,864...43,736,277
JBrowse link
G H3c1 H3 clustered histone 1 decreases expression ISO ferric oxide analog results in decreased expression of H3C1 mRNA CTD PMID:25086211 NCBI chr17:41,367,824...41,368,902
Ensembl chr17:41,368,386...41,368,856
JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO ferric oxide analog results in increased expression of HBEGF mRNA CTD PMID:25086211 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
JBrowse link
G Heatr3 HEAT repeat containing 3 decreases expression ISO ferric oxide analog results in decreased expression of HEATR3 mRNA CTD PMID:25086211 NCBI chr19:18,892,477...18,930,502
Ensembl chr19:18,893,144...18,930,509
JBrowse link
G Hebp1 heme binding protein 1 increases expression ISO ferric oxide analog results in increased expression of HEBP1 mRNA CTD PMID:25086211 NCBI chr 4:167,974,318...168,003,859
Ensembl chr 4:167,974,319...168,003,854
JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated increases expression ISO ferric oxide analog results in increased expression of HILPDA mRNA CTD PMID:25086211 NCBI chr 4:57,871,076...57,875,206
Ensembl chr 4:57,871,110...57,874,557
JBrowse link
G Hist1h2ail1 histone cluster 1 H2a family member I like 1 decreases expression ISO ferric oxide analog results in decreased expression of H3C6 mRNA CTD PMID:25086211 NCBI chr17:41,568,666...41,569,076
Ensembl chr17:41,568,471...41,569,109
JBrowse link
G Hist1h2bd histone cluster 1 H2B family member D decreases expression ISO ferric oxide analog results in decreased expression of H2BC14 mRNA CTD PMID:25086211 NCBI chr17:42,792,887...42,793,268 JBrowse link
G Hist1h2bl histone cluster 1 H2B family member l decreases expression ISO ferric oxide analog results in decreased expression of H2BC7 mRNA CTD PMID:24525745 PMID:25086211 NCBI chr17:42,708,646...42,709,435 JBrowse link
G Hist2h2be histone cluster 2 H2B family member E decreases expression ISO ferric oxide analog results in decreased expression of H2BC11 mRNA CTD PMID:25086211 NCBI chr 2:183,780,449...183,783,030 JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO ferric oxide analog results in increased expression of HMOX1 mRNA CTD PMID:24525745 PMID:25086211 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 increases expression ISO ferric oxide analog results in increased expression of HSD3B7 mRNA CTD PMID:25086211 NCBI chr 1:182,411,836...182,415,447
Ensembl chr 1:182,412,151...182,415,442
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of HSPA1A mRNA CTD PMID:20540983
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of HSPA8 mRNA CTD PMID:20540983 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression ISO ferric oxide results in decreased expression of HSPD1 protein CTD PMID:28077287 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Hyal1 hyaluronidase 1 increases expression
decreases expression
ISO ferric oxide analog results in increased expression of HYAL1 mRNA
ferric oxide analog results in decreased expression of HYAL1 mRNA
CTD PMID:24525745 PMID:25086211 NCBI chr 8:108,250,654...108,254,526
Ensembl chr 8:108,250,667...108,260,210
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO ferric oxide results in increased expression of ICAM1 protein CTD PMID:21439359 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Icam2 intercellular adhesion molecule 2 decreases expression ISO ferric oxide analog results in decreased expression of ICAM2 mRNA CTD PMID:25086211 NCBI chr10:91,308,608...91,319,536
Ensembl chr10:91,308,538...91,315,293
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression ISO ferric oxide analog results in increased expression of ID1 mRNA CTD PMID:24525745 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein increases expression ISO ferric oxide analog results in increased expression of ID3 mRNA CTD PMID:24525745 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
JBrowse link
G Il10ra interleukin 10 receptor subunit alpha decreases expression ISO ferric oxide analog results in decreased expression of IL10RA mRNA CTD PMID:25086211 NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061
JBrowse link
G Il1b interleukin 1 beta increases secretion ISO ferric oxide analog results in increased secretion of IL1B protein
ferric oxide results in increased secretion of IL1B protein
CTD PMID:24525745 PMID:24885771 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of IL2 protein CTD PMID:20540983 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4 interleukin 4 multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of IL4 protein; ferric oxide inhibits the reaction [Ovalbumin results in increased expression of IL4 protein] CTD PMID:20540983 PMID:23147377 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5 interleukin 5 multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of IL5 protein CTD PMID:20540983 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il6 interleukin 6 multiple interactions
increases secretion
ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of IL6 protein
ferric oxide results in increased secretion of IL6 protein
ferric oxide analog results in increased secretion of IL6 protein
CTD PMID:20540983 PMID:24525745 PMID:24885771 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Irf7 interferon regulatory factor 7 decreases expression ISO ferric oxide analog results in decreased expression of IRF7 mRNA CTD PMID:25086211 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases phosphorylation EXP ferric oxide analog results in increased phosphorylation of JUN protein CTD PMID:22995439 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Klf2 Kruppel-like factor 2 decreases expression ISO ferric oxide analog results in decreased expression of KLF2 mRNA CTD PMID:25086211 NCBI chr16:17,521,773...17,523,723
Ensembl chr16:17,514,552...17,523,944
JBrowse link
G Klf4 Kruppel like factor 4 decreases expression ISO ferric oxide analog results in decreased expression of KLF4 mRNA CTD PMID:25086211 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 multiple interactions EXP [ferric oxide analog co-treated with Acrolein] results in decreased expression of LAMP1 protein CTD PMID:24847785 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 increases expression ISO ferric oxide analog results in increased expression of LAMP2 protein CTD PMID:25086211 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522
JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 decreases expression ISO ferric oxide analog results in decreased expression of LILRB4B mRNA CTD PMID:24525745 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660
JBrowse link
G Lima1 LIM domain and actin binding 1 increases expression ISO ferric oxide analog results in increased expression of LIMA1 mRNA CTD PMID:25086211 NCBI chr 7:130,901,717...131,001,573
Ensembl chr 7:130,901,717...131,001,473
JBrowse link
G Lims2 LIM zinc finger domain containing 2 increases expression ISO ferric oxide analog results in increased expression of LIMS2 mRNA CTD PMID:25086211 NCBI chr18:23,553,813...23,592,137
Ensembl chr18:23,553,937...23,592,137
JBrowse link
G LOC120093505 U6 spliceosomal RNA decreases expression ISO ferric oxide analog results in decreased expression of RNU6 mRNA CTD PMID:24525745 NCBI chr 6:9,344,990...9,345,096
Ensembl chr 6:9,344,990...9,345,096
JBrowse link
G Lst1 leukocyte specific transcript 1 decreases expression ISO ferric oxide analog results in decreased expression of LST1 mRNA CTD PMID:24525745 NCBI chr20:3,634,680...3,639,731
Ensembl chr20:3,634,749...3,637,997
JBrowse link
G Lyz2 lysozyme 2 decreases expression ISO ferric oxide analog results in decreased expression of LYZ2 mRNA CTD PMID:25086211 NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106
JBrowse link
G Mafb MAF bZIP transcription factor B increases expression ISO ferric oxide analog results in increased expression of MAFB mRNA CTD PMID:24525745 NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha increases expression ISO ferric oxide analog results in increased expression of MAP1LC3A protein CTD PMID:25086211 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression ISO ferric oxide analog results in increased expression of MAP1LC3B protein CTD PMID:24068039 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO
EXP
ferric oxide analog results in increased phosphorylation of MAPK1 protein
[ferric oxide analog co-treated with Acrolein] results in increased phosphorylation of MAPK1 protein
CTD PMID:24068039 PMID:24847785 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO
EXP
ferric oxide analog results in increased phosphorylation of MAPK3 protein
[ferric oxide analog co-treated with Acrolein] results in increased phosphorylation of MAPK3 protein
CTD PMID:24068039 PMID:24847785 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mat2a methionine adenosyltransferase 2A decreases expression
increases expression
ISO ferric oxide analog results in decreased expression of MAT2A mRNA
ferric oxide analog results in increased expression of MAT2A mRNA
CTD PMID:24525745 PMID:25086211 NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493
JBrowse link
G Mef2c myocyte enhancer factor 2C decreases expression ISO ferric oxide analog results in decreased expression of MEF2C mRNA CTD PMID:25086211 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Mmp12 matrix metallopeptidase 12 multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of MMP12 mRNA CTD PMID:20540983 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
G Mmp19 matrix metallopeptidase 19 multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of MMP19 mRNA CTD PMID:20540983 NCBI chr 7:1,221,229...1,229,555
Ensembl chr 7:1,221,343...1,229,555
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of MMP2 mRNA CTD PMID:20540983 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp23 matrix metallopeptidase 23 multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of MMP23 mRNA CTD PMID:20540983 NCBI chr 5:166,239,643...166,242,734
Ensembl chr 5:166,239,644...166,242,433
JBrowse link
G Mmp7 matrix metallopeptidase 7 increases expression ISO ferric oxide results in increased expression of MMP7 protein CTD PMID:24885771 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
JBrowse link
G Msmb microseminoprotein, beta affects expression ISO ferric oxide affects the expression of MSMB mRNA CTD PMID:28077287 NCBI chr16:7,366,536...7,387,124
Ensembl chr16:7,366,536...7,387,123
JBrowse link
G Naa80 N(alpha)-acetyltransferase 80, NatH catalytic subunit increases expression ISO ferric oxide analog results in increased expression of NAA80 mRNA CTD PMID:25086211 NCBI chr 8:108,254,314...108,257,564
Ensembl chr 8:108,253,302...108,257,563
JBrowse link
G Nckap5l NCK-associated protein 5-like decreases expression ISO ferric oxide analog results in decreased expression of NCKAP5L mRNA CTD PMID:24525745 NCBI chr 7:130,553,683...130,591,886
Ensembl chr 7:130,555,368...130,591,857
JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression ISO ferric oxide analog results in increased expression of NDRG1 mRNA CTD PMID:25086211 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 increases expression ISO ferric oxide analog results in increased expression of NEDD9 mRNA CTD PMID:24525745 NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019
JBrowse link
G Nox4 NADPH oxidase 4 increases expression ISO ferric oxide results in increased expression of NOX4 protein CTD PMID:28077287 PMID:28993115 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Npm3 nucleophosmin/nucleoplasmin, 3 decreases expression ISO ferric oxide analog results in decreased expression of NPM3 mRNA CTD PMID:25086211 NCBI chr 1:244,595,638...244,597,623
Ensembl chr 1:244,595,644...244,597,591
JBrowse link
G Nrp1 neuropilin 1 decreases expression ISO ferric oxide analog results in decreased expression of NRP1 mRNA CTD PMID:25086211 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Nt5c2 5'-nucleotidase, cytosolic II increases expression ISO ferric oxide analog results in increased expression of NT5C2 mRNA CTD PMID:24525745 NCBI chr 1:245,770,993...245,896,925
Ensembl chr 1:245,772,277...245,897,913
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator decreases expression ISO ferric oxide analog results in decreased expression of NUPR1 mRNA CTD PMID:24525745 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 decreases expression ISO ferric oxide analog results in decreased expression of OAS2 mRNA CTD PMID:25086211 NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371
JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like decreases expression ISO ferric oxide analog results in decreased expression of OASL1 mRNA CTD PMID:25086211 NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO ferric oxide analog results in increased cleavage of PARP1 protein
ferric oxide results in decreased expression of and results in increased cleavage of PARP1 protein
ferric oxide results in increased cleavage of PARP1 protein
CTD PMID:26991130 PMID:27270449 PMID:28993115 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pate4 prostate and testis expressed 4 affects expression ISO ferric oxide affects the expression of PATE4 mRNA CTD PMID:28077287 NCBI chr 8:33,988,812...33,991,552
Ensembl chr 8:33,988,812...33,991,552
JBrowse link
G Pcdh7 protocadherin 7 decreases expression ISO ferric oxide analog results in decreased expression of PCDH7 mRNA CTD PMID:25086211 NCBI chr14:52,471,801...52,901,696
Ensembl chr14:52,475,610...52,902,051
Ensembl chr14:52,475,610...52,902,051
JBrowse link
G Per2 period circadian regulator 2 increases expression ISO ferric oxide analog results in increased expression of PER2 mRNA CTD PMID:25086211 NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
JBrowse link
G Pes1 pescadillo ribosomal biogenesis factor 1 decreases expression ISO ferric oxide analog results in decreased expression of PES1 mRNA CTD PMID:25086211 NCBI chr14:78,850,754...78,867,134
Ensembl chr14:78,850,709...78,867,134
JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 increases expression ISO ferric oxide analog results in increased expression of PHLDA1 mRNA CTD PMID:25086211 NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861
JBrowse link
G Plekhf1 pleckstrin homology and FYVE domain containing 1 increases expression ISO ferric oxide analog results in increased expression of PLEKHF1 mRNA CTD PMID:25086211 NCBI chr 1:90,908,304...90,915,862
Ensembl chr 1:90,904,742...90,915,820
JBrowse link
G Plk2 polo-like kinase 2 increases expression ISO ferric oxide analog results in increased expression of PLK2 mRNA CTD PMID:25086211 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
JBrowse link
G Plk3 polo-like kinase 3 increases expression ISO ferric oxide analog results in increased expression of PLK3 mRNA CTD PMID:25086211 NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317
JBrowse link
G Plpbp pyridoxal phosphate binding protein increases expression ISO ferric oxide analog results in increased expression of PLPBP mRNA CTD PMID:25086211 NCBI chr16:65,003,292...65,014,886
Ensembl chr16:65,002,223...65,014,886
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A decreases expression ISO ferric oxide analog results in decreased expression of PPP1R15A mRNA CTD PMID:24525745 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Prf1 perforin 1 decreases expression ISO ferric oxide analog results in decreased expression of PRF1 mRNA CTD PMID:24525745 NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701
JBrowse link
G Prmt6 protein arginine methyltransferase 6 decreases expression ISO ferric oxide analog results in decreased expression of PRMT6 mRNA CTD PMID:25086211 NCBI chr 2:197,927,750...197,932,980
Ensembl chr 2:197,927,220...197,933,648
JBrowse link
G Prr18 proline rich 18 increases expression ISO ferric oxide analog results in increased expression of PRR18 mRNA CTD PMID:25086211 NCBI chr 1:52,400,215...52,404,492
Ensembl chr 1:52,400,215...52,404,309
JBrowse link
G Prr33 proline rich 33 decreases expression ISO ferric oxide analog results in decreased expression of PRR33 mRNA CTD PMID:25086211 NCBI chr 1:197,644,903...197,650,774
Ensembl chr 1:197,644,902...197,650,714
JBrowse link
G Rab15 RAB15, member RAS oncogene family increases expression ISO ferric oxide analog results in increased expression of RAB15 mRNA CTD PMID:25086211 NCBI chr 6:95,499,584...95,524,073
Ensembl chr 6:95,499,587...95,523,942
JBrowse link
G Rad50 RAD50 double strand break repair protein decreases expression ISO ferric oxide analog results in decreased expression of RAD50 mRNA CTD PMID:24525745 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396
JBrowse link
G Rbak RB-associated KRAB zinc finger increases expression ISO ferric oxide analog results in increased expression of RBAK mRNA CTD PMID:24525745 NCBI chr12:11,375,314...11,388,937
Ensembl chr12:11,375,318...11,388,934
JBrowse link
G Rcan1 regulator of calcineurin 1 increases expression ISO ferric oxide analog results in increased expression of RCAN1 mRNA CTD PMID:25086211 NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045
JBrowse link
G Rcbtb2 RCC1 and BTB domain containing protein 2 increases expression ISO ferric oxide analog results in increased expression of RCBTB2 mRNA CTD PMID:24525745 NCBI chr15:48,319,809...48,364,441
Ensembl chr15:48,323,866...48,383,750
JBrowse link
G Rilpl1 Rab interacting lysosomal protein-like 1 decreases expression ISO ferric oxide analog results in decreased expression of RILPL1 mRNA CTD PMID:24525745 NCBI chr12:32,071,870...32,109,687
Ensembl chr12:32,071,693...32,109,938
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 multiple interactions EXP [ferric oxide analog co-treated with Acrolein] results in increased expression of RIPK1 protein CTD PMID:24847785 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 multiple interactions EXP [ferric oxide analog co-treated with Acrolein] results in increased expression of RIPK3 protein CTD PMID:24847785 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of H2-EB1 mRNA CTD PMID:20540983 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of H2-T23 mRNA CTD PMID:20540983 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
G Rusc2 RUN and SH3 domain containing 2 increases expression ISO ferric oxide analog results in increased expression of RUSC2 mRNA CTD PMID:25086211 NCBI chr 5:57,628,397...57,675,524
Ensembl chr 5:57,629,904...57,675,524
JBrowse link
G Samd9 sterile alpha motif domain containing 9 decreases expression ISO ferric oxide analog results in decreased expression of SAMD9L mRNA CTD PMID:25086211 NCBI chr 4:31,164,639...31,184,325
Ensembl chr 4:31,164,510...31,184,322
JBrowse link
G Serpinb1a serpin family B member 1A decreases expression ISO ferric oxide analog results in decreased expression of SERPINB1A mRNA CTD PMID:24525745 NCBI chr17:31,590,695...31,599,102
Ensembl chr17:31,590,677...31,599,102
JBrowse link
G Skil SKI-like proto-oncogene increases expression ISO ferric oxide analog results in increased expression of SKIL mRNA CTD PMID:24525745 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080
JBrowse link
G Slamf8 SLAM family member 8 increases expression ISO ferric oxide analog results in increased expression of SLAMF8 mRNA CTD PMID:24525745 NCBI chr13:85,047,729...85,057,571
Ensembl chr13:85,047,727...85,057,211
JBrowse link
G Slc11a1 solute carrier family 11 member 1 increases expression ISO ferric oxide analog results in increased expression of SLC11A1 mRNA CTD PMID:25086211 NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101
JBrowse link
G Slc46a3 solute carrier family 46, member 3 decreases expression ISO ferric oxide analog results in decreased expression of SLC46A3 mRNA CTD PMID:25086211 NCBI chr12:7,140,610...7,157,093
Ensembl chr12:7,140,668...7,157,092
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of SLPI mRNA CTD PMID:20540983 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
JBrowse link
G Sod1 superoxide dismutase 1 increases expression ISO ferric oxide analog results in increased expression of SOD1 protein CTD PMID:24068039 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO ferric oxide analog results in increased expression of SOD2 protein; ferric oxide results in increased expression of SOD2 protein CTD PMID:24068039 PMID:25086211 PMID:26991130 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Spata24 spermatogenesis associated 24 decreases expression ISO ferric oxide analog results in decreased expression of SPATA24 mRNA CTD PMID:24525745 NCBI chr18:27,249,047...27,257,129
Ensembl chr18:27,248,609...27,257,124
JBrowse link
G Tatdn2 TatD DNase domain containing 2 decreases expression ISO ferric oxide analog results in decreased expression of TATDN2 mRNA CTD PMID:24525745 NCBI chr 4:146,845,156...146,865,708
Ensembl chr 4:146,845,156...146,860,897
JBrowse link
G Tbc1d2 TBC1 domain family, member 2 increases expression
decreases expression
ISO ferric oxide analog results in increased expression of TBC1D2 mRNA
ferric oxide analog results in decreased expression of TBC1D2 mRNA
CTD PMID:24525745 PMID:25086211 NCBI chr 5:60,884,114...60,931,717
Ensembl chr 5:60,884,124...60,931,352
JBrowse link
G Tbxas1 thromboxane A synthase 1 increases expression ISO ferric oxide analog results in increased expression of TBXAS1 mRNA CTD PMID:24525745 NCBI chr 4:67,664,963...67,837,096
Ensembl chr 4:67,665,007...67,837,096
JBrowse link
G Tf transferrin increases expression EXP ferric oxide results in increased expression of TF mRNA CTD PMID:16428268 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tfrc transferrin receptor decreases expression ISO ferric oxide analog results in decreased expression of TFRC mRNA CTD PMID:25086211 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tgfbi transforming growth factor, beta induced increases expression ISO ferric oxide analog results in increased expression of TGFBI mRNA CTD PMID:24525745 NCBI chr17:7,955,603...7,984,903
Ensembl chr17:7,955,603...7,985,240
JBrowse link
G Tgm2 transglutaminase 2 increases expression ISO ferric oxide analog results in increased expression of TGM2 mRNA CTD PMID:25086211 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of TIMP1 mRNA CTD PMID:20540983 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression ISO ferric oxide results in increased expression of TIMP2 protein CTD PMID:24885771 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
JBrowse link
G Tlr2 toll-like receptor 2 increases expression ISO ferric oxide analog results in increased expression of TLR2 mRNA CTD PMID:24525745 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tmem176a transmembrane protein 176A decreases expression ISO ferric oxide analog results in decreased expression of TMEM176A mRNA CTD PMID:25086211 NCBI chr 4:77,774,940...77,778,620
Ensembl chr 4:77,774,843...77,778,620
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases secretion
ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of TNF protein
ferric oxide results in increased secretion of TNF protein
ferric oxide analog results in increased secretion of TNF protein
CTD PMID:20540983 PMID:24068039 PMID:24525745 PMID:24885771 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnni3 troponin I3, cardiac type increases expression ISO ferric oxide results in increased expression of TNNI3 protein CTD PMID:28993115 NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580
JBrowse link
G Tp53 tumor protein p53 increases phosphorylation
multiple interactions
EXP ferric oxide analog results in increased phosphorylation of TP53 protein
[ferric oxide analog co-treated with Acrolein] results in increased expression of TP53 protein
CTD PMID:22995439 PMID:24847785 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases expression ISO ferric oxide analog results in increased expression of TRP53INP1 mRNA CTD PMID:25086211 NCBI chr 5:24,253,986...24,272,250
Ensembl chr 5:24,260,568...24,267,968
JBrowse link
G Tpr translocated promoter region, nuclear basket protein decreases expression ISO ferric oxide analog results in decreased expression of TPR mRNA CTD PMID:24525745 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496
JBrowse link
G Trib3 tribbles pseudokinase 3 decreases expression ISO ferric oxide analog results in decreased expression of