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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:isoflavone
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Accession:CHEBI:18220 term browser browse the term
Definition:A simplest member of the class of isoflavones that is 4H-chromen-4-one in which the hydrogen at position 3 is replaced by a phenyl group.
Synonyms:exact_synonym: 3-phenyl-4H-chromen-4-one
 related_synonym: 3-Phenylchromone;   3-phenyl-4H-1-benzopyran-4-one;   Formula=C15H10O2;   InChI=1S/C15H10O2/c16-15-12-8-4-5-9-14(12)17-10-13(15)11-6-2-1-3-7-11/h1-10H;   InChIKey=GOMNOOKGLZYEJT-UHFFFAOYSA-N;   Isoflavon;   SMILES=O=c1c(coc2ccccc12)-c1ccccc1
 alt_id: CHEBI:14467;   CHEBI:24892;   CHEBI:6013
 xref: Beilstein:157731;   CAS:574-12-9;   Gmelin:1224833;   KEGG:C00799;   LIPID_MAPS_instance:LMPK12050000;   Reaxys:157731



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afrormosin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 affects activity ISO afromosin affects the activity of ABCC1 protein CTD PMID:15796199 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
calycosin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd14b abhydrolase domain containing 14b increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of ABHD14B protein CTD PMID:24455688 NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:107,088,069...107,092,119
JBrowse link
G Ache acetylcholinesterase increases expression
multiple interactions
EXP 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of ACHE mRNA
7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of and results in increased activity of ACHE protein
CTD PMID:27019979 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Blvrb biliverdin reductase B increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of BLVRB protein CTD PMID:24455688 NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375
JBrowse link
G Ccnb1 cyclin B1 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of CCNB1 mRNA CTD PMID:24455688 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in decreased expression of CCND3 mRNA CTD PMID:24455688 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccng1 cyclin G1 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of CCNG1 mRNA CTD PMID:24455688 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cdk7 cyclin-dependent kinase 7 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of CDK7 mRNA CTD PMID:24455688 NCBI chr 2:31,840,545...31,865,447
Ensembl chr 2:31,840,558...31,865,383
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in decreased expression of CDKN1A mRNA CTD PMID:24455688 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in decreased expression of CDKN1C mRNA CTD PMID:24455688 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D decreases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in decreased expression of CDKN2D mRNA CTD PMID:24455688 NCBI chr 8:19,831,874...19,834,640
Ensembl chr 8:19,831,866...19,834,674
JBrowse link
G Epo erythropoietin increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of EPO mRNA CTD PMID:21309574 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Erp29 endoplasmic reticulum protein 29 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of ERP29 protein CTD PMID:24455688 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of and results in decreased degradation of HIF1A protein
7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of HIF1A mRNA
CTD PMID:21309574 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmgb1 high mobility group box 1 decreases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in decreased expression of HMGB1 protein CTD PMID:24455688 NCBI chr12:5,973,062...5,978,565 JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein] CTD PMID:31726037 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL1RL1 mRNA] CTD PMID:31726037 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256
JBrowse link
G Il33 interleukin 33 multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 mRNA]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 protein] CTD PMID:31726037 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Il6 interleukin 6 multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein] CTD PMID:31726037 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Krt1 keratin 1 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of KRT1 protein CTD PMID:24455688 NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844
JBrowse link
G Lasp1 LIM and SH3 protein 1 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of LASP1 protein CTD PMID:24455688 NCBI chr10:82,795,177...82,835,659
Ensembl chr10:82,795,137...82,943,292
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased phosphorylation of MAPK1 protein CTD PMID:20686605 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased phosphorylation of MAPK3 protein CTD PMID:20686605 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in decreased expression of MCM5 mRNA CTD PMID:24455688 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of MCM6 mRNA CTD PMID:24455688 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 protein] CTD PMID:31726037 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of NME1 protein CTD PMID:24455688 NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of PEBP1 protein CTD PMID:24455688 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
JBrowse link
G Pgam1 phosphoglycerate mutase 1 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of PGAM1 protein CTD PMID:24455688 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
JBrowse link
G Pnpo pyridoxamine 5'-phosphate oxidase increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of PNPO protein CTD PMID:24455688 NCBI chr10:81,924,584...81,930,844
Ensembl chr10:81,924,569...81,930,871
JBrowse link
G Prdx1 peroxiredoxin 1 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of PRDX1 protein CTD PMID:24455688 NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856
JBrowse link
G Prdx2 peroxiredoxin 2 decreases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in decreased expression of PRDX2 protein CTD PMID:24455688 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
JBrowse link
G Prima1 proline rich membrane anchor 1 increases expression EXP 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of PRIMA1 mRNA CTD PMID:27019979 NCBI chr 6:122,338,365...122,390,955
Ensembl chr 6:122,338,370...122,389,921
JBrowse link
G Rad9a RAD9 checkpoint clamp component A decreases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in decreased expression of RAD9A mRNA CTD PMID:24455688 NCBI chr 1:201,488,511...201,553,582
Ensembl chr 1:201,487,136...201,553,608
JBrowse link
G Rbx1 ring-box 1 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of RBX1 mRNA CTD PMID:24455688 NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of RELA protein] CTD PMID:31726037 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Skp1 S-phase kinase-associated protein 1 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of SKP1 mRNA CTD PMID:24455688 NCBI chr10:36,401,987...36,417,066
Ensembl chr10:36,402,153...36,417,388
JBrowse link
G Skp2 S-phase kinase associated protein 2 decreases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in decreased expression of SKP2 mRNA CTD PMID:24455688 NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338
JBrowse link
G Stip1 stress-induced phosphoprotein 1 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of STIP1 protein CTD PMID:24455688 NCBI chr 1:204,209,434...204,228,452
Ensembl chr 1:204,178,932...204,228,476
JBrowse link
G Tagln2 transgelin 2 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of TAGLN2 protein CTD PMID:24455688 NCBI chr13:84,966,980...84,973,973
Ensembl chr13:84,967,009...84,973,972
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein] CTD PMID:31726037 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein] CTD PMID:31726037 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Ube3a ubiquitin protein ligase E3A increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of UBE3A mRNA CTD PMID:24455688 NCBI chr 1:110,070,260...110,161,675
Ensembl chr 1:110,070,480...110,157,250
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of 7,3'-dihydroxy-4'-methoxyisoflavone CTD PMID:25044472 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of 7,3'-dihydroxy-4'-methoxyisoflavone CTD PMID:25044472 NCBI chr 9:88,791,216...88,808,465 JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation ISO UGT1A8 protein results in increased glucuronidation of 7,3'-dihydroxy-4'-methoxyisoflavone CTD PMID:25044472 NCBI chr 9:88,727,094...88,808,465 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of 7,3'-dihydroxy-4'-methoxyisoflavone CTD PMID:25044472 NCBI chr 9:88,696,981...88,808,465 JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 increases glucuronidation ISO UGT2B7 protein results in increased glucuronidation of 7,3'-dihydroxy-4'-methoxyisoflavone CTD PMID:25044472 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
JBrowse link
calycosin-7-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epo erythropoietin increases expression ISO calycosin-7-O-beta-D-glucoside results in increased expression of EPO mRNA CTD PMID:21309574 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
ISO calycosin-7-O-beta-D-glucoside results in increased expression of and results in decreased degradation of HIF1A protein
calycosin-7-O-beta-D-glucoside results in increased expression of HIF1A mRNA
CTD PMID:21309574 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
glycitein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ABCA1 mRNA CTD PMID:16963248 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of ACSL3 mRNA CTD PMID:27424125 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Add2 adducin 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ADD2 mRNA CTD PMID:16963248 NCBI chr 4:118,444,594...118,538,505
Ensembl chr 4:118,497,416...118,538,505
JBrowse link
G Ahr aryl hydrocarbon receptor increases activity ISO glycitein results in increased activity of AHR protein CTD PMID:17869316 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ALDH1A2 mRNA CTD PMID:27424125 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107
JBrowse link
G Anpep alanyl aminopeptidase, membrane multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ANPEP mRNA CTD PMID:27424125 NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO glycitein results in decreased expression of ARHGDIA mRNA CTD PMID:15757668 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of ATOH8 mRNA CTD PMID:27424125 NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168
JBrowse link
G Atp6v0a2 ATPase H+ transporting V0 subunit a2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ATP6V0A2 mRNA CTD PMID:16963248 NCBI chr12:31,949,863...31,979,777 JBrowse link
G Baz1a bromodomain adjacent to zinc finger domain, 1A multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of BAZ1A mRNA CTD PMID:16963248 NCBI chr 6:72,389,701...72,512,516
Ensembl chr 6:72,389,703...72,512,459
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of BCKDK mRNA CTD PMID:27424125 NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633
JBrowse link
G Bpgm bisphosphoglycerate mutase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of BPGM mRNA CTD PMID:27424125 NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:63,140,018...63,168,581
JBrowse link
G Cabp5 calcium binding protein 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CABP5 mRNA CTD PMID:27424125 NCBI chr 1:74,350,811...74,363,830
Ensembl chr 1:74,350,811...74,363,830
JBrowse link
G Cacybp calcyclin binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CACYBP mRNA CTD PMID:27424125 NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CASP8AP2 mRNA CTD PMID:27424125 NCBI chr 5:47,014,501...47,052,276
Ensembl chr 5:47,014,667...47,052,275
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO glycitein results in decreased expression of CCNA2 CTD PMID:21161820 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO glycitein results in increased expression of CCND1 mRNA CTD PMID:19800779 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cd200r1 CD200 receptor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CD200R1 mRNA CTD PMID:27424125 NCBI chr11:55,886,937...55,921,217
Ensembl chr11:55,887,717...55,921,285
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases activity ISO glycitein results in decreased activity of CDK4 protein CTD PMID:21161820 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO ESR2 affects the reaction [glycitein results in increased expression of CDKN1A] CTD PMID:21161820 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cfap251 cilia and flagella associated protein 251 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CFAP251 mRNA CTD PMID:27424125 NCBI chr12:33,261,622...33,337,028
Ensembl chr12:33,261,476...33,293,932
JBrowse link
G Cybrd1 cytochrome b reductase 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CYBRD1 mRNA CTD PMID:27424125 NCBI chr 3:55,934,874...55,962,132
Ensembl chr 3:55,934,874...55,962,108
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of CYP11A1 mRNA CTD PMID:28964809 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Dennd2d DENN domain containing 2D multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of DENND2D mRNA CTD PMID:27424125 NCBI chr 2:193,973,231...193,992,275
Ensembl chr 2:193,973,231...193,992,270
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT3A mRNA CTD PMID:28964809 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
JBrowse link
G Dock3 dedicator of cyto-kinesis 3 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of DOCK3 mRNA CTD PMID:16963248 NCBI chr 8:107,552,462...107,903,527
Ensembl chr 8:107,552,463...107,903,514
JBrowse link
G Dpp9 dipeptidyl peptidase 9 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of DPP9 mRNA CTD PMID:27424125 NCBI chr 9:1,011,347...1,046,337
Ensembl chr 9:1,011,351...1,046,541
JBrowse link
G Edrf1 erythroid differentiation regulatory factor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of EDRF1 mRNA CTD PMID:27424125 NCBI chr 1:188,441,514...188,478,743
Ensembl chr 1:188,441,634...188,478,701
JBrowse link
G Efhd1 EF-hand domain family, member D1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of EFHD1 mRNA CTD PMID:27424125 NCBI chr 9:87,938,259...87,984,917
Ensembl chr 9:87,938,284...87,984,917
JBrowse link
G Epha1 Eph receptor A1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of EPHA1 mRNA CTD PMID:16963248 NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846
JBrowse link
G Espn espin multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ESPN mRNA CTD PMID:16963248 NCBI chr 5:162,626,560...162,660,439
Ensembl chr 5:162,626,560...162,660,256
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
affects binding
ISO glycitein inhibits the reaction [Estradiol binds to ESR1 protein]
glycitein binds to ESR1 protein
CTD PMID:14579009 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
affects response to substance
ISO
EXP
ESR2 affects the reaction [glycitein results in increased expression of CDKN1A]
[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of ESR2 mRNA
ESR2 affects the susceptibility to glycitein
CTD PMID:21161820 PMID:28964809 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Fam171a2 family with sequence similarity 171, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FAM171A2 mRNA CTD PMID:27424125 NCBI chr10:87,393,888...87,404,051
Ensembl chr10:87,394,007...87,404,053
JBrowse link
G Fam180a family with sequence similarity 180, member A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM180A mRNA CTD PMID:27424125 NCBI chr 4:63,992,867...64,008,047
Ensembl chr 4:63,992,867...64,008,047
JBrowse link
G Fam210b family with sequence similarity 210, member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM210B mRNA CTD PMID:27424125 NCBI chr 3:161,118,228...161,128,400
Ensembl chr 3:161,118,239...161,128,397
JBrowse link
G Fam241b family with sequence similarity 241 member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of FAM241B mRNA CTD PMID:27424125 NCBI chr20:30,052,315...30,055,247
Ensembl chr20:30,052,324...30,055,084
JBrowse link
G Fgd6 FYVE, RhoGEF and PH domain containing 6 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FGD6 mRNA CTD PMID:27424125 NCBI chr 7:28,597,609...28,712,908
Ensembl chr 7:28,597,609...28,712,456
JBrowse link
G Fhl2 four and a half LIM domains 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FHL2 mRNA CTD PMID:27424125 NCBI chr 9:45,388,979...45,462,530
Ensembl chr 9:45,388,981...45,431,192
JBrowse link
G Fmn2 formin 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of FMN2 mRNA CTD PMID:16963248 NCBI chr13:86,454,256...86,771,437 JBrowse link
G Galnt15 polypeptide N-acetylgalactosaminyltransferase 15 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of GALNT15 mRNA CTD PMID:27424125 NCBI chr16:7,227,232...7,267,002
Ensembl chr16:7,227,271...7,267,014
JBrowse link
G Gng5 G protein subunit gamma 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of GNG5 mRNA CTD PMID:27424125 NCBI chr 2:235,394,680...235,403,177 JBrowse link
G Hipk4 homeodomain interacting protein kinase 4 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of HIPK4 mRNA CTD PMID:27424125 NCBI chr 1:82,810,708...82,821,080
Ensembl chr 1:82,810,708...82,821,077
JBrowse link
G Hmcn1 hemicentin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of HMCN1 mRNA CTD PMID:27424125 NCBI chr13:62,615,461...63,084,524
Ensembl chr13:62,615,461...63,084,524
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of HSD3B1 mRNA CTD PMID:28964809 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
JBrowse link
G Ifrd2 interferon-related developmental regulator 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of IFRD2 mRNA CTD PMID:16963248 NCBI chr 8:108,260,969...108,266,191
Ensembl chr 8:108,260,969...108,266,194
JBrowse link
G Il6r interleukin 6 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of IL6R mRNA CTD PMID:27424125 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Irf2bp1 interferon regulatory factor 2 binding protein 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of IRF2BP1 mRNA CTD PMID:16963248 NCBI chr 1:78,652,736...78,655,437
Ensembl chr 1:78,652,412...78,655,530
JBrowse link
G Isg20l2 interferon stimulated exonuclease gene 20-like 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ISG20L2 mRNA CTD PMID:27424125 NCBI chr 2:173,396,780...173,407,102
Ensembl chr 2:173,396,780...173,406,614
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases activity ISO glycitein results in increased activity of JUN protein CTD PMID:17088408 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kcng2 potassium voltage-gated channel modifier subfamily G member 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of KCNG2 mRNA CTD PMID:16963248 NCBI chr18:73,742,224...73,810,420
Ensembl chr18:73,743,074...73,808,723
JBrowse link
G Kdm5a lysine demethylase 5A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of KDM5A mRNA CTD PMID:27424125 NCBI chr 4:153,565,909...153,643,912
Ensembl chr 4:153,565,846...153,642,422
JBrowse link
G Kitlg KIT ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KITLG mRNA CTD PMID:27424125 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KNSTRN mRNA CTD PMID:27424125 NCBI chr 3:105,800,762...105,820,555
Ensembl chr 3:105,800,954...105,820,715
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LDLRAP1 mRNA CTD PMID:27424125 NCBI chr 5:146,955,607...146,978,601
Ensembl chr 5:146,955,607...146,978,601
JBrowse link
G Lmod1 leiomodin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LMOD1 mRNA CTD PMID:27424125 NCBI chr13:46,754,048...46,796,186
Ensembl chr13:46,754,033...46,794,900
JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of LRG1 mRNA CTD PMID:27424125 NCBI chr 9:947,516...949,773
Ensembl chr 9:947,516...949,813
JBrowse link
G Lsr lipolysis stimulated lipoprotein receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LSR mRNA CTD PMID:27424125 NCBI chr 1:86,185,769...86,201,952
Ensembl chr 1:86,186,431...86,201,952
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO glycitein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]
glycitein results in increased phosphorylation of MAPK1 protein
CTD PMID:17088408 PMID:20188714 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO glycitein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]
glycitein results in increased phosphorylation of MAPK3 protein
CTD PMID:17088408 PMID:20188714 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mmp3 matrix metallopeptidase 3 decreases expression ISO glycitein results in decreased expression of MMP3 mRNA; glycitein results in decreased expression of MMP3 protein CTD PMID:20188714 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
ISO glycitein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]
glycitein results in decreased expression of MMP9 mRNA; glycitein results in decreased expression of MMP9 protein
CTD PMID:20188714 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mrpl33 mitochondrial ribosomal protein L33 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of MRPL33 mRNA CTD PMID:27424125 NCBI chr 6:24,825,804...24,834,061
Ensembl chr 6:24,825,827...24,833,834
JBrowse link
G Mtmr11 myotubularin related protein 11 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of MTMR11 mRNA CTD PMID:27424125 NCBI chr 2:183,721,983...183,732,148
Ensembl chr 2:183,723,530...183,732,148
JBrowse link
G Myof myoferlin multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of MYOF mRNA CTD PMID:27424125 NCBI chr 1:235,673,666...235,822,413
Ensembl chr 1:235,673,666...235,822,334
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases activity
ISO glycitein inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; glycitein inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
glycitein results in decreased activity of NOS2 protein
CTD PMID:11308324 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of NR4A1 mRNA CTD PMID:27424125 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 protein; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased methylation of NR5A1 promoter; decitabine inhibits the reaction [[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA] CTD PMID:28964809 NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 increases expression ISO glycitein results in increased expression of NRIP1 mRNA CTD PMID:15757668 NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761
JBrowse link
G Olfml3 olfactomedin-like 3 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of OLFML3 mRNA CTD PMID:16963248 NCBI chr 2:191,244,221...191,247,050
Ensembl chr 2:191,244,221...191,247,050
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO glycitein results in decreased expression of PCNA CTD PMID:21161820 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pdlim2 PDZ and LIM domain 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of PDLIM2 mRNA CTD PMID:16963248 NCBI chr15:45,235,421...45,250,187
Ensembl chr15:45,237,477...45,249,242
JBrowse link
G Pnn pinin, desmosome associated protein multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of PNN mRNA CTD PMID:16963248 NCBI chr 6:76,758,138...76,766,451
Ensembl chr 6:76,758,117...76,766,889
JBrowse link
G Pou4f2 POU class 4 homeobox 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of POU4F2 mRNA CTD PMID:16963248 NCBI chr19:29,486,686...29,490,327
Ensembl chr19:29,486,686...29,490,327
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of PRKACA mRNA CTD PMID:27424125 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Prpf40a pre-mRNA processing factor 40 homolog A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PRPF40A mRNA CTD PMID:27424125 NCBI chr 3:37,625,585...37,689,859
Ensembl chr 3:37,627,690...37,690,886
JBrowse link
G Pspc1 paraspeckle component 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PSPC1 mRNA CTD PMID:27424125 NCBI chr15:30,828,617...30,911,315
Ensembl chr15:30,828,626...30,911,202
JBrowse link
G Pth1r parathyroid hormone 1 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of PTH1R mRNA CTD PMID:27424125 NCBI chr 8:110,693,910...110,725,458
Ensembl chr 8:110,697,485...110,719,729
JBrowse link
G Rassf5 Ras association domain family member 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of RASSF5 mRNA CTD PMID:27424125 NCBI chr13:42,637,513...42,703,024
Ensembl chr13:42,637,549...42,703,024
JBrowse link
G Rgs22 regulator of G-protein signaling 22 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of RGS22 mRNA CTD PMID:27424125 NCBI chr 7:67,188,531...67,308,805
Ensembl chr 7:67,188,519...67,308,875
JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 increases expression ISO glycitein results in increased expression of RPS6KA3 mRNA CTD PMID:15757668 NCBI chr  X:35,517,306...35,623,296
Ensembl chr  X:35,517,306...35,623,207
JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of S1PR3 mRNA CTD PMID:27424125 NCBI chr17:13,781,050...13,794,408
Ensembl chr17:13,781,050...13,794,505
JBrowse link
G Selplg selectin P ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SELPLG mRNA CTD PMID:27424125 NCBI chr12:42,796,690...42,809,908
Ensembl chr12:42,796,580...42,812,585
JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of SGPP1 mRNA CTD PMID:16963248 NCBI chr 6:94,425,339...94,446,534
Ensembl chr 6:94,425,339...94,446,534
JBrowse link
G Siglec10 sialic acid binding Ig-like lectin 10 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SIGLEC10 mRNA CTD PMID:27424125 NCBI chr 1:93,817,301...93,826,376
Ensembl chr 1:93,817,335...93,825,931
JBrowse link
G Slc12a2 solute carrier family 12 member 2 decreases expression ISO glycitein results in decreased expression of SLC12A2 mRNA CTD PMID:15757668 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440
JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SLC16A1 mRNA CTD PMID:27424125 NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611
JBrowse link
G Slc22a8 solute carrier family 22 member 8 increases uptake ISO SLC22A8 protein results in increased uptake of glycitein analog CTD PMID:21244849 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
JBrowse link
G Snx30 sorting nexin family member 30 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SNX30 mRNA CTD PMID:27424125 NCBI chr 5:74,683,902...74,813,013
Ensembl chr 5:74,684,015...74,792,631
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions
increases activity
ISO glycitein promotes the reaction [SP1 protein binds to VDR promoter]; U 0126 inhibits the reaction [glycitein results in increased activity of SP1 protein] CTD PMID:17088408 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
JBrowse link
G Ssc5d scavenger receptor cysteine rich family member with 5 domains multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SSC5D mRNA CTD PMID:27424125 NCBI chr 1:68,891,942...68,910,462
Ensembl chr 1:68,891,949...68,909,743
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR protein CTD PMID:28964809 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Stc1 stanniocalcin 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of STC1 mRNA CTD PMID:16963248 NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of STYXL1 mRNA CTD PMID:27424125 NCBI chr12:20,907,410...20,940,232
Ensembl chr12:20,907,435...20,939,752
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of SUMO1 mRNA CTD PMID:27424125 NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761
JBrowse link
G Tacr3 tachykinin receptor 3 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of TACR3 mRNA CTD PMID:16963248 NCBI chr 2:223,266,536...223,363,791
Ensembl chr 2:223,266,536...223,363,791
JBrowse link
G Tc2n tandem C2 domains, nuclear multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of TC2N mRNA CTD PMID:27424125 NCBI chr 6:120,761,112...120,856,835
Ensembl chr 6:120,761,119...120,849,326
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of TNFAIP6 mRNA CTD PMID:16963248 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
JBrowse link
G Tp53 tumor protein p53 increases expression ISO glycitein results in increased expression of TP53 protein CTD PMID:19800779 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp53i11 tumor protein p53 inducible protein 11 decreases expression
multiple interactions
ISO glycitein results in decreased expression of TP53I11 mRNA
[daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of TP53I11 mRNA
CTD PMID:15757668 PMID:27424125 NCBI chr 3:79,144,824...79,160,056
Ensembl chr 3:79,144,895...79,160,050
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of UCHL1 mRNA CTD PMID:16963248 NCBI chr14:41,485,033...41,495,590
Ensembl chr14:41,485,031...41,495,590
JBrowse link
G Vcpip1 valosin containing protein interacting protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of VCPIP1 mRNA CTD PMID:27424125 NCBI chr 5:9,534,247...9,560,889
Ensembl chr 5:9,534,129...9,562,040
JBrowse link
G Vdr vitamin D receptor multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [glycitein results in increased expression of VDR protein]; glycitein promotes the reaction [SP1 protein binds to VDR promoter]; U 0126 inhibits the reaction [glycitein results in increased expression of VDR protein]
glycitein results in increased expression of VDR mRNA; glycitein results in increased expression of VDR protein
CTD PMID:17088408 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
puerarin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO puerarin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of ACACA mRNA] CTD PMID:31273855 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acacb acetyl-CoA carboxylase beta multiple interactions ISO puerarin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of ACACB mRNA] CTD PMID:31273855 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain increases expression ISO puerarin results in increased expression of ACADM mRNA CTD PMID:31273855 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Ache acetylcholinesterase multiple interactions ISO puerarin inhibits the reaction [lead acetate results in decreased expression of ACHE protein] CTD PMID:23501611 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acly ATP citrate lyase increases expression ISO puerarin results in increased expression of ACLY mRNA CTD PMID:20706672 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression ISO puerarin results in increased expression of ACOX1 mRNA CTD PMID:31273855 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO puerarin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of ACTA2 mRNA]; puerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:27318789 PMID:31273855 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions
ISO puerarin results in increased phosphorylation of AKT1 protein
fulvestrant inhibits the reaction [puerarin results in increased phosphorylation of AKT1 protein]
CTD PMID:21884717 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alb albumin multiple interactions EXP
ISO
puerarin inhibits the reaction [Carbon Tetrachloride results in decreased expression of ALB protein]; puerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of ALB protein] CTD PMID:23146695 PMID:23500774 PMID:27318789 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aqp1 aquaporin 1 increases expression ISO puerarin results in increased expression of AQP1 mRNA CTD PMID:20706672 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) increases expression ISO puerarin results in increased expression of AQP3 mRNA CTD PMID:20706672 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
JBrowse link
G Ar androgen receptor decreases expression ISO puerarin results in decreased expression of AR mRNA CTD PMID:20706672 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO
EXP
puerarin results in increased expression of BAX protein
puerarin inhibits the reaction [cadmium acetate results in increased expression of BAX mRNA]; puerarin inhibits the reaction [cadmium acetate results in increased expression of BAX protein]
CTD PMID:16055262 PMID:27717697 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO
EXP
puerarin results in decreased expression of BCL2 mRNA; puerarin results in decreased expression of BCL2 protein
puerarin inhibits the reaction [[Ethanol co-treated with Carbon Tetrachloride] results in increased expression of BCL2 mRNA]; puerarin inhibits the reaction [cadmium acetate results in decreased expression of BCL2 mRNA]; puerarin inhibits the reaction [cadmium acetate results in decreased expression of BCL2 protein]
arsenic trioxide promotes the reaction [puerarin results in decreased expression of BCL2 mRNA]
CTD PMID:16055262 PMID:16426832 PMID:20416161 PMID:27717697 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression
ISO arsenic trioxide promotes the reaction [puerarin results in decreased expression of BIRC5 mRNA] CTD PMID:20416161 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
ISO
EXP
arsenic trioxide promotes the reaction [puerarin results in increased expression of CASP3 protein]
puerarin inhibits the reaction [Carbon Tetrachloride results in increased activity of CASP3 protein]
puerarin results in increased activity of CASP3 protein
puerarin inhibits the reaction [cadmium acetate results in increased activity of CASP3 protein]; puerarin inhibits the reaction [lead nitrate results in increased activity of CASP3 protein]; puerarin results in decreased expression of and results in decreased activity of CASP3 protein
CTD PMID:16041641 PMID:16055262 PMID:20416161 PMID:24505050 PMID:27318789 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases expression
multiple interactions
ISO puerarin results in increased expression of CASP8 protein
arsenic trioxide promotes the reaction [puerarin results in increased expression of CASP8 protein]
CTD PMID:20416161 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cat catalase multiple interactions EXP puerarin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CAT protein]; puerarin inhibits the reaction [lead nitrate results in decreased activity of CAT protein] CTD PMID:23315276 PMID:24975872 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions ISO puerarin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of CCN2 mRNA]; puerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of CCN2 mRNA] CTD PMID:27318789 PMID:31273855 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Cdh1 cadherin 1 increases expression ISO puerarin results in increased expression of CDH1 mRNA CTD PMID:20706672 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO puerarin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of COL1A1 mRNA]; puerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA] CTD PMID:27318789 PMID:31273855 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions EXP puerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 protein] CTD PMID:23500774 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression ISO puerarin results in increased expression of CPT1A mRNA CTD PMID:31273855 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO puerarin inhibits the reaction [nickel sulfate results in increased phosphorylation of CREB1 protein] CTD PMID:26607348 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Cygb cytoglobin decreases expression ISO puerarin results in decreased expression of CYGB mRNA CTD PMID:20706672 NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases expression
ISO puerarin inhibits the reaction [CYP2E1 protein results in increased hydroxylation of aniline]
puerarin results in increased expression of CYP2E1 protein
CTD PMID:18038910 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions EXP puerarin affects the reaction [Lead affects the expression of CYP7A1] CTD PMID:22001170 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Dsg3 desmoglein 3 decreases expression ISO puerarin results in decreased expression of DSG3 mRNA CTD PMID:20706672 NCBI chr18:11,798,905...11,833,415
Ensembl chr18:11,798,900...11,830,818
JBrowse link
G Egf epidermal growth factor decreases expression ISO puerarin results in decreased expression of EGF mRNA CTD PMID:20706672 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
decreases phosphorylation
EXP puerarin inhibits the reaction [lead nitrate results in increased phosphorylation of EIF4EBP1 protein]
puerarin results in decreased phosphorylation of EIF4EBP1 protein
CTD PMID:27762461 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Esr1 estrogen receptor 1 decreases expression EXP puerarin results in decreased expression of ESR1 mRNA CTD PMID:22919047 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 decreases activity
decreases expression
ISO
EXP
puerarin results in decreased activity of ESR2 protein
puerarin results in decreased expression of ESR2 mRNA
CTD PMID:18937077 PMID:20706672 PMID:22919047 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Faslg Fas ligand multiple interactions
increases expression
ISO arsenic trioxide promotes the reaction [puerarin results in increased expression of FASLG protein] CTD PMID:20416161 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO puerarin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of FASN mRNA] CTD PMID:31273855 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbn1 fibrillin 1 decreases expression ISO puerarin results in decreased expression of FBN1 mRNA CTD PMID:20706672 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Fbn2 fibrillin 2 decreases expression ISO puerarin results in decreased expression of FBN2 mRNA CTD PMID:20706672 NCBI chr18:51,499,737...51,703,976
Ensembl chr18:51,499,737...51,703,976
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression ISO puerarin results in increased expression of FGF1 mRNA CTD PMID:20706672 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO puerarin results in increased expression of FOS mRNA CTD PMID:17142977 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions ISO
EXP
[1-Methyl-4-phenylpyridinium co-treated with puerarin] results in decreased phosphorylation of FYN protein
[1-Methyl-4-phenylpyridinium co-treated with puerarin] results in decreased phosphorylation of FYN protein; FYN protein affects the reaction [[1-Methyl-4-phenylpyridinium co-treated with puerarin] results in increased activity of NFE2L2 protein]; Lithium Chloride inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with puerarin] results in decreased phosphorylation of FYN protein]
CTD PMID:32763437 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO
EXP
[1-Methyl-4-phenylpyridinium co-treated with puerarin] results in increased expression of GCLC mRNA; [1-Methyl-4-phenylpyridinium co-treated with puerarin] results in increased expression of GCLC protein; NFE2L2 protein affects the reaction [[1-Methyl-4-phenylpyridinium co-treated with puerarin] results in increased expression of GCLC mRNA]; NFE2L2 protein affects the reaction [[1-Methyl-4-phenylpyridinium co-treated with puerarin] results in increased expression of GCLC protein] CTD PMID:32763437 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions ISO 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [puerarin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of GDNF protein]]; puerarin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of GDNF protein] CTD PMID:27796870 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 multiple interactions
increases expression
ISO Sirolimus inhibits the reaction [puerarin results in increased expression of GPER1 protein] CTD PMID:27796870 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Gpi glucose-6-phosphate isomerase multiple interactions EXP puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of GPI mRNA] CTD PMID:33404196 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO puerarin inhibits the reaction [nickel sulfate results in increased activity of GPT protein] CTD PMID:26607348 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP
ISO
[1-Methyl-4-phenylpyridinium co-treated with puerarin] results in increased phosphorylation of GSK3B protein CTD PMID:32763437 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsr glutathione-disulfide reductase increases expression
multiple interactions
ISO
EXP
puerarin results in increased expression of GSR protein
puerarin inhibits the reaction [Lead results in decreased activity of GSR protein]
CTD PMID:18038910 PMID:22001170 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Has1 hyaluronan synthase 1 decreases expression ISO puerarin results in decreased expression of HAS1 mRNA CTD PMID:20706672 NCBI chr 1:58,693,411...58,705,653
Ensembl chr 1:58,693,411...58,705,397
JBrowse link
G Hk1 hexokinase 1 multiple interactions EXP puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of HK1 mRNA] CTD PMID:33404196 NCBI chr20:30,230,488...30,332,161
Ensembl chr20:30,230,486...30,332,131
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions EXP puerarin affects the reaction [Lead affects the expression of HMGCR] CTD PMID:22001170 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO
EXP
bisindolylmaleimide I inhibits the reaction [puerarin results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [puerarin results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [puerarin results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [puerarin results in increased expression of HMOX1 protein]; PRKCD mutant form inhibits the reaction [puerarin results in increased expression of HMOX1 protein]; rottlerin inhibits the reaction [puerarin results in increased expression of HMOX1 protein]
puerarin inhibits the reaction [Carbon Tetrachloride results in decreased expression of HMOX1 protein]
puerarin results in increased expression of HMOX1 mRNA; puerarin results in increased expression of HMOX1 protein
CTD PMID:20060010 PMID:24975872 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression ISO puerarin results in increased expression of HSPB1 mRNA CTD PMID:20706672 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO puerarin inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; puerarin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:21884717 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifng interferon gamma multiple interactions ISO puerarin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of IFNG mRNA] CTD PMID:31273855 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression
multiple interactions
ISO puerarin results in decreased expression of IGF1 mRNA
puerarin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]
CTD PMID:20706672 PMID:23927877 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO puerarin results in decreased expression of IL1A mRNA CTD PMID:20706672 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO puerarin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of IL1B mRNA] CTD PMID:31273855 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO puerarin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of IL6 mRNA]; puerarin inhibits the reaction [nickel sulfate results in increased expression of IL6 protein] CTD PMID:26607348 PMID:31273855 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Insr insulin receptor multiple interactions ISO puerarin inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA] CTD PMID:23927877 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Kl Klotho decreases expression ISO puerarin results in decreased expression of KL mRNA CTD PMID:20706672 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
JBrowse link
G Ldha lactate dehydrogenase A multiple interactions EXP puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of LDHA protein] CTD PMID:33404196 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions EXP puerarin affects the reaction [Lead affects the expression of LDLR] CTD PMID:22001170 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lif LIF, interleukin 6 family cytokine decreases expression EXP puerarin results in decreased expression of LIF mRNA CTD PMID:22919047 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO
EXP
puerarin results in increased phosphorylation of MAPK1 protein
puerarin inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK1 protein]
CTD PMID:21884717 PMID:24975872 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO
EXP
puerarin results in increased phosphorylation of MAPK3 protein
puerarin inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK3 protein]
CTD PMID:21884717 PMID:24975872 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
increases expression
ISO arsenic trioxide promotes the reaction [puerarin results in increased expression of MAPK8 protein]
puerarin results in increased phosphorylation of MAPK8 protein
CTD PMID:20416161 PMID:21884717 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation ISO puerarin results in increased phosphorylation of MAPK9 protein CTD PMID:21884717 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mc1r melanocortin 1 receptor decreases expression ISO puerarin results in decreased expression of MC1R mRNA CTD PMID:20706672 NCBI chr19:51,452,448...51,455,375 JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP puerarin inhibits the reaction [Carbon Tetrachloride results in decreased expression of MMP2 mRNA] CTD PMID:23500774 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I increases expression
multiple interactions
ISO
EXP
puerarin results in increased expression of COX1 mRNA
puerarin inhibits the reaction [lead nitrate results in decreased expression of COX1 mRNA]
CTD PMID:20706672 PMID:23315276 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II multiple interactions EXP puerarin inhibits the reaction [lead nitrate results in decreased expression of COX2 mRNA] CTD PMID:23315276 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III multiple interactions EXP puerarin inhibits the reaction [lead nitrate results in decreased expression of COX3 mRNA] CTD PMID:23315276 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
increases phosphorylation
ISO
EXP
Sirolimus inhibits the reaction [puerarin results in increased phosphorylation of MTOR protein]
puerarin inhibits the reaction [lead nitrate results in increased phosphorylation of MTOR protein]
CTD PMID:27762461 PMID:27796870 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO puerarin results in decreased expression of MYC protein CTD PMID:16055262 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
affects localization
EXP
ISO
[1-Methyl-4-phenylpyridinium co-treated with puerarin] results in increased activity of and affects the localization of NFE2L2 protein; FYN protein affects the reaction [[1-Methyl-4-phenylpyridinium co-treated with puerarin] results in increased activity of NFE2L2 protein]; Lithium Chloride inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with puerarin] results in increased activity of NFE2L2 protein]; puerarin inhibits the reaction [Carbon Tetrachloride affects the localization of NFE2L2 protein]
[1-Methyl-4-phenylpyridinium co-treated with puerarin] affects the localization of NFE2L2 protein; NFE2L2 protein affects the reaction [[1-Methyl-4-phenylpyridinium co-treated with puerarin] results in increased expression of GCLC mRNA]; NFE2L2 protein affects the reaction [[1-Methyl-4-phenylpyridinium co-treated with puerarin] results in increased expression of GCLC protein]
puerarin affects the localization of NFE2L2 protein
CTD PMID:24975872 PMID:32763437 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions EXP puerarin inhibits the reaction [Ethanol inhibits the reaction [Lipopolysaccharides results in increased activity of [NFKB1 protein binds to NFKB1 protein]]]; puerarin inhibits the reaction [Ethanol results in decreased activity of [NFKB1 protein binds to NFKB1 protein]]; puerarin inhibits the reaction [Ethanol results in increased activity of [RELA protein binds to NFKB1 protein]] CTD PMID:17887948 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO puerarin inhibits the reaction [Carbon Tetrachloride results in increased degradation of NFKBIA protein] CTD PMID:27318789 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions ISO puerarin inhibits the reaction [lead acetate results in decreased expression of NOS1 protein] CTD PMID:23501611 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression
multiple interactions
ISO
EXP
puerarin results in decreased expression of NOS2 mRNA
puerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 mRNA]; puerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 protein]
CTD PMID:20706672 PMID:23146695 PMID:24975872 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
increases phosphorylation
increases expression
increases activity
ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[puerarin results in increased phosphorylation of NOS3 protein] which results in increased abundance of Nitric Oxide]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [puerarin results in increased phosphorylation of NOS3 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[puerarin results in increased phosphorylation of NOS3 protein] which results in increased abundance of Nitric Oxide]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [puerarin results in increased phosphorylation of NOS3 protein]; [puerarin results in increased phosphorylation of NOS3 protein] which results in increased abundance of Nitric Oxide; fulvestrant inhibits the reaction [[puerarin results in increased phosphorylation of NOS3 protein] which results in increased abundance of Nitric Oxide]; fulvestrant inhibits the reaction [puerarin results in increased phosphorylation of NOS3 protein]; W 7 inhibits the reaction [[puerarin results in increased phosphorylation of NOS3 protein] which results in increased abundance of Nitric Oxide]; W 7 inhibits the reaction [puerarin results in increased phosphorylation of NOS3 protein]
puerarin inhibits the reaction [lead acetate results in decreased expression of NOS3 protein]
puerarin results in increased expression of NOS3 mRNA
puerarin results in increased activity of NOS3 protein
CTD PMID:20706672 PMID:21884717 PMID:23501611 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
EXP puerarin inhibits the reaction [Carbon Tetrachloride results in decreased expression of NQO1 protein]
puerarin results in increased expression of NQO1 protein
CTD PMID:24975872 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions EXP
ISO
puerarin inhibits the reaction [cadmium acetate results in increased cleavage of PARP1 protein]
puerarin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of PARP1 protein]; puerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of PARP1 protein]
CTD PMID:27318789 PMID:27717697 PMID:31273855 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pfkp phosphofructokinase, platelet multiple interactions EXP puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of PFKP mRNA] CTD PMID:33404196 NCBI chr17:63,729,743...63,794,021
Ensembl chr17:63,729,780...63,794,018
JBrowse link
G Pgam1 phosphoglycerate mutase 1 multiple interactions EXP puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of PGAM1 mRNA] CTD PMID:33404196 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
JBrowse link
G Pgr progesterone receptor decreases expression
increases expression
ISO
EXP
puerarin results in decreased expression of PGR mRNA
puerarin results in increased expression of PGR protein
CTD PMID:17142977 PMID:20706672 PMID:22919047 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 increases expression ISO puerarin results in increased expression of PLOD3 mRNA CTD PMID:20706672 NCBI chr12:19,676,384...19,686,945
Ensembl chr12:19,676,386...19,686,960
JBrowse link
G Pml PML nuclear body scaffold multiple interactions
decreases expression
ISO arsenic trioxide promotes the reaction [puerarin results in decreased expression of PML mRNA alternative form] CTD PMID:20416161 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO puerarin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of PPARA mRNA]; puerarin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of PPARA protein]; puerarin inhibits the reaction [Streptozocin results in decreased expression of PPARA mRNA] CTD PMID:23927877 PMID:31273855 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
decreases expression
EXP
ISO
puerarin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PPARG protein]
puerarin results in decreased expression of PPARG mRNA
CTD PMID:20706672 PMID:23500774 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions EXP puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of PPARGC1A protein] CTD PMID:33404196 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Prkcd protein kinase C, delta multiple interactions
increases phosphorylation
ISO PRKCD mutant form inhibits the reaction [puerarin results in increased expression of HMOX1 protein]
puerarin results in increased phosphorylation of PRKCD protein
CTD PMID:20060010 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Ptger1 prostaglandin E receptor 1 decreases expression ISO puerarin results in decreased expression of PTGER1 mRNA CTD PMID:20706672 NCBI chr19:24,470,258...24,473,687
Ensembl chr19:24,467,532...24,473,559
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions
EXP
ISO
puerarin results in decreased expression of PTGS2 mRNA
puerarin inhibits the reaction [nickel sulfate results in increased expression of PTGS2 protein]
puerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein]
CTD PMID:22919047 PMID:24975872 PMID:26607348 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions
increases expression
decreases expression
ISO arsenic trioxide promotes the reaction [puerarin results in decreased expression of RARA mRNA alternative form]
puerarin results in increased expression of RARA mRNA
CTD PMID:20416161 PMID:20706672 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP
puerarin inhibits the reaction [TNF protein results in increased expression of RELA protein]
puerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of RELA protein]; puerarin inhibits the reaction [nickel sulfate affects the localization of RELA protein]
puerarin inhibits the reaction [Carbon Tetrachloride affects the localization of RELA protein]; puerarin inhibits the reaction [Ethanol results in increased activity of [RELA protein binds to NFKB1 protein]]
CTD PMID:17887948 PMID:21884717 PMID:24975872 PMID:26607348 PMID:27318789 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 increases phosphorylation
multiple interactions
ISO
EXP
puerarin results in increased phosphorylation of RPS6KB1 protein
puerarin inhibits the reaction [lead nitrate results in increased phosphorylation of RPS6KB1 protein]
Sirolimus inhibits the reaction [puerarin results in increased phosphorylation of RPS6KB1 protein]
CTD PMID:27762461 PMID:27796870 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of SIRT1 protein] CTD PMID:33404196 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc25a4 solute carrier family 25 member 4 multiple interactions EXP puerarin inhibits the reaction [cadmium acetate results in increased expression of SLC25A4 mRNA]; puerarin inhibits the reaction [cadmium acetate results in increased expression of SLC25A4 protein] CTD PMID:27717697 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
G Slc25a5 solute carrier family 25 member 5 multiple interactions EXP puerarin inhibits the reaction [cadmium acetate results in decreased expression of SLC25A5 mRNA]; puerarin inhibits the reaction [cadmium acetate results in decreased expression of SLC25A5 protein] CTD PMID:27717697 NCBI chr  X:116,031,896...116,034,963
Ensembl chr  X:116,031,803...116,034,967
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions EXP puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of SLC2A1 protein] CTD PMID:33404196 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Sod3 superoxide dismutase 3 decreases expression ISO puerarin results in decreased expression of SOD3 mRNA CTD PMID:20706672 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions EXP puerarin inhibits the reaction [lead nitrate results in increased expression of SQSTM1 protein] CTD PMID:27762461 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 decreases expression ISO puerarin results in decreased expression of SRD5A2 mRNA CTD PMID:20706672 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO puerarin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of SREBF1 mRNA] CTD PMID:31273855 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Tert telomerase reverse transcriptase decreases expression ISO puerarin results in decreased expression of TERT mRNA CTD PMID:20706672 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP
ISO
puerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein]
puerarin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of TGFB1 mRNA]; puerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]
CTD PMID:23146695 PMID:27318789 PMID:31273855 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP puerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA] CTD PMID:23500774 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO puerarin inhibits the reaction [nickel sulfate results in increased expression of TLR4 protein] CTD PMID:26607348 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases activity
ISO
EXP
puerarin inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; puerarin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; puerarin inhibits the reaction [TNF protein results in increased expression of RELA protein]
puerarin inhibits the reaction [nickel sulfate results in increased expression of TNF protein]
puerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]
puerarin results in decreased activity of TNF protein
CTD PMID:21884717 PMID:23146695 PMID:26607348 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 increases expression ISO puerarin results in increased expression of TPT1 mRNA CTD PMID:20706672 NCBI chr15:51,156,728...51,159,629
Ensembl chr15:51,146,154...51,159,625
JBrowse link
G Txn1 thioredoxin 1 increases expression ISO puerarin results in increased expression of TXN mRNA CTD PMID:20706672 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Tyrp1 tyrosinase-related protein 1 decreases expression ISO puerarin results in decreased expression of TYRP1 mRNA CTD PMID:20706672 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions EXP puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in increased expression of UCP2 protein] CTD PMID:33404196 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases metabolic processing ISO UGT1A1 protein results in increased metabolism of puerarin CTD PMID:22648071 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases metabolic processing ISO UGT1A3 protein results in increased metabolism of puerarin CTD PMID:22648071 NCBI chr 9:88,791,216...88,808,465 JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases metabolic processing ISO UGT1A6 protein results in increased metabolism of puerarin CTD PMID:22648071 NCBI chr 9:88,747,229...88,808,465 JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 increases metabolic processing ISO UGT1A8 protein results in increased metabolism of puerarin CTD PMID:22648071 NCBI chr 9:88,727,094...88,808,465 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases metabolic processing ISO UGT1A9 protein results in increased metabolism of puerarin CTD PMID:22648071 NCBI chr 9:88,696,981...88,808,465 JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression EXP puerarin results in decreased expression of VEGFA mRNA CTD PMID:22919047 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Xiap X-linked inhibitor of apoptosis increases expression EXP puerarin results in increased expression of XIAP protein CTD PMID:16041641 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
tectoridin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadm acyl-CoA dehydrogenase medium chain multiple interactions ISO tectoridin inhibits the reaction [Ethanol results in decreased expression of ACADM mRNA] CTD PMID:20637825 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions ISO tectoridin inhibits the reaction [Ethanol results in decreased expression of ACOX1 mRNA] CTD PMID:20637825 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO tectoridin inhibits the reaction [Ethanol results in decreased expression of CPT1A mRNA] CTD PMID:20637825 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO tectoridin inhibits the reaction [Ethanol results in increased expression of DGAT1 mRNA] CTD PMID:20637825 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions ISO tectoridin inhibits the reaction [Ethanol results in increased expression of DGAT2 mRNA] CTD PMID:20637825 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial multiple interactions ISO tectoridin inhibits the reaction [Ethanol results in increased expression of GPAM mRNA] CTD PMID:20637825 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO tectoridin inhibits the reaction [Ethanol results in decreased expression of PPARA mRNA] CTD PMID:20637825 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19795
    chemical entity 19795
      atom 19794
        nonmetal atom 19681
          oxygen atom 19418
            oxygen molecular entity 19418
              flavonoids 11136
                isoflavonoid 3778
                  isoflavones 3763
                    isoflavone 254
                      3',4'-dihydroxyisoflavone 0
                      4'-O-methylisoflavone 0
                      5,6,7,4'-tetramethoxyisoflavone 0
                      7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavone + 0
                      7-hydroxy-2',4',5'-trimethoxyisoflavone 0
                      7-hydroxy-5-methoxy-6,8-dimethylisoflavone 0
                      afrormosin 1
                      betavulgarin 0
                      calycosin + 47
                      dalpatein 0
                      glycitein + 104
                      irigenin + 0
                      isoderrone 0
                      isowighteone 0
                      licoricone 0
                      orobol + 0
                      paniculatin 0
                      piscerythramine 0
                      pisonianone 0
                      puerarin + 119
                      tectorigenin + 7
                      wighteone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19795
    subatomic particle 19794
      composite particle 19794
        hadron 19794
          baryon 19794
            nucleon 19794
              atomic nucleus 19794
                atom 19794
                  main group element atom 19693
                    p-block element atom 19693
                      carbon group element atom 19614
                        carbon atom 19604
                          organic molecular entity 19604
                            organic group 18713
                              organic divalent group 18697
                                organodiyl group 18697
                                  carbonyl group 18646
                                    carbonyl compound 18646
                                      ketone 16955
                                        cyclic ketone 15523
                                          isoflavones 3763
                                            isoflavone 254
                                              3',4'-dihydroxyisoflavone 0
                                              4'-O-methylisoflavone 0
                                              5,6,7,4'-tetramethoxyisoflavone 0
                                              7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavone + 0
                                              7-hydroxy-2',4',5'-trimethoxyisoflavone 0
                                              7-hydroxy-5-methoxy-6,8-dimethylisoflavone 0
                                              afrormosin 1
                                              betavulgarin 0
                                              calycosin + 47
                                              dalpatein 0
                                              glycitein + 104
                                              irigenin + 0
                                              isoderrone 0
                                              isowighteone 0
                                              licoricone 0
                                              orobol + 0
                                              paniculatin 0
                                              piscerythramine 0
                                              pisonianone 0
                                              puerarin + 119
                                              tectorigenin + 7
                                              wighteone 0
paths to the root