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ONTOLOGY REPORT - ANNOTATIONS


Term:benzylpenicillin
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Accession:CHEBI:18208 term browser browse the term
Definition:A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group.
Synonyms:exact_synonym: 2,2-dimethyl-6beta-(phenylacetamido)penam-3alpha-carboxylic acid
 related_synonym: (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;   6-(2-phenylacetamido)penicillanic acid;   Formula=C16H18N2O4S;   InChI=1S/C16H18N2O4S/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22)/t11-,12+,14-/m1/s1;   InChIKey=JGSARLDLIJGVTE-MBNYWOFBSA-N;   PCG;   PENICILLIN G;   PG;   SMILES=N12C([C@H]([C@]1(SC([C@@H]2C(O)=O)(C)C)[H])NC(CC3=CC=CC=C3)=O)=O;   bencilpenicilina;   bensylpenicillin;   benzyl benicillin;   benzylpenicilline;   benzylpenicillinic acid;   benzylpenicillinum;   free penicillin II
 alt_id: CHEBI:14743;   CHEBI:25866;   CHEBI:45073;   CHEBI:7962
 xref: Beilstein:44740 "Beilstein";   CAS:61-33-6 "ChemIDplus";   CAS:61-33-6 "KEGG COMPOUND";   DrugBank:DB01053;   Drug_Central:2082 "DrugCentral";   Gmelin:781913 "Gmelin";   HMDB:HMDB0015186;   KEGG:C05551;   KEGG:D02336;   LINCS:LSM-3229
 xref_mesh: MESH:D010400
 xref: PDBeChem:PNN;   PMID:10930630 "Europe PMC";   PMID:11431418 "Europe PMC";   PMID:11906332 "Europe PMC";   PMID:12569987 "Europe PMC";   PMID:12850488 "Europe PMC";   PMID:1384868 "Europe PMC";   PMID:16033609 "Europe PMC";   PMID:1709917 "Europe PMC";   PMID:2083978 "Europe PMC";   PMID:24485692 "Europe PMC";   PMID:24631718 "Europe PMC";   PMID:25998949 "Europe PMC";   PMID:27731424 "Europe PMC";   PMID:29017833 "Europe PMC";   PMID:29355985 "Europe PMC";   PMID:6161899 "Europe PMC";   PMID:7602118 "Europe PMC";   PMID:7716788 "Europe PMC";   Patent:US3024169;   Reaxys:44740 "Reaxys";   Wikipedia:Benzylpenicillin
 cyclic_relationship: is_conjugate_acid_of CHEBI:51354


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benzylpenicillin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:6480464
G Abcc4 ATP binding cassette subfamily C member 4 JBrowse link 15 103,695,415 103,927,980 RGD:6480464
G Acaca acetyl-CoA carboxylase alpha JBrowse link 10 71,519,392 71,719,910 RGD:6480464
G Acly ATP citrate lyase JBrowse link 10 88,392,248 88,442,845 RGD:6480464
G Afp alpha-fetoprotein JBrowse link 14 19,141,755 19,159,919 RGD:6480464
G Anxa8 annexin A8 JBrowse link 16 10,417,174 10,432,388 RGD:6480464
G Atf3 activating transcription factor 3 JBrowse link 13 109,817,892 109,849,632 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Ccr2 C-C motif chemokine receptor 2 RGD:6480464
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:6480464
G Cd86 CD86 molecule JBrowse link 11 67,060,305 67,117,990 RGD:6480464
G Cer1 cerberus 1, DAN family BMP antagonist JBrowse link 5 101,003,019 101,006,375 RGD:6480464
G Ces1d carboxylesterase 1D JBrowse link 19 15,195,514 15,239,827 RGD:6480464
G Cpt1a carnitine palmitoyltransferase 1A JBrowse link 1 218,568,157 218,629,679 RGD:6480464
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:6480464
G Cs citrate synthase JBrowse link 7 2,752,680 2,778,963 RGD:6480464
G Dcn decorin JBrowse link 7 38,742,250 38,782,282 RGD:6480464
G Defb1 defensin beta 1 JBrowse link 16 75,294,385 75,309,127 RGD:6480464
G Dgat1 diacylglycerol O-acyltransferase 1 JBrowse link 7 117,566,363 117,576,735 RGD:6480464
G Dgat2 diacylglycerol O-acyltransferase 2 JBrowse link 1 164,113,459 164,143,818 RGD:6480464
G Fabp1 fatty acid binding protein 1 JBrowse link 4 99,063,181 99,066,957 RGD:6480464
G Fasn fatty acid synthase JBrowse link 10 109,987,735 110,005,901 RGD:6480464
G Frzb frizzled-related protein JBrowse link 3 67,635,604 67,668,772 RGD:6480464
G Gclm glutamate cysteine ligase, modifier subunit JBrowse link 2 225,827,504 225,847,876 RGD:6480464
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial JBrowse link 1 275,843,823 275,906,880 RGD:6480464
G Hdac7 histone deacetylase 7 JBrowse link 7 139,280,396 139,319,108 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:6480464
G Igfbp5 insulin-like growth factor binding protein 5 JBrowse link 9 80,154,230 80,166,813 RGD:6480464
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:6480464
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Kdr kinase insert domain receptor JBrowse link 14 34,727,677 34,787,127 RGD:6480464
G Lbp lipopolysaccharide binding protein JBrowse link 3 154,786,232 154,812,910 RGD:6480464
G Mesp1 mesoderm posterior bHLH transcription factor 1 JBrowse link 1 141,532,390 141,533,908 RGD:6480464
G Mmp1 matrix metallopeptidase 1 JBrowse link 8 5,703,206 5,723,593 RGD:6480464
G Mttp microsomal triglyceride transfer protein JBrowse link 2 243,366,181 243,407,608 RGD:6480464
G Muc2 mucin 2, oligomeric mucus/gel-forming JBrowse link 1 214,663,929 214,693,197 RGD:6480464
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:6480464
G Nefm neurofilament medium JBrowse link 15 44,855,307 44,860,604 RGD:6480464
G Nes nestin JBrowse link 2 187,343,109 187,352,972 RGD:6480464
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:6480464
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:6480464
G Pgd phosphogluconate dehydrogenase JBrowse link 5 165,966,128 165,982,327 RGD:6480464
G Pir pirin JBrowse link X 31,852,322 31,968,152 RGD:6480464
G Pnpla6 patatin-like phospholipase domain containing 6 JBrowse link 12 2,068,749 2,098,139 RGD:6480464
G Reg3g regenerating family member 3 gamma JBrowse link 4 109,529,679 109,532,234 RGD:6480464
G Retnlb resistin like beta JBrowse link 11 54,565,471 54,567,578 RGD:6480464
G Scd stearoyl-CoA desaturase JBrowse link 1 264,159,966 264,173,061 RGD:6480464
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:6480464
G Slc22a12 solute carrier family 22 member 12 JBrowse link 1 221,910,787 221,919,277 RGD:6480464
G Slc22a20 solute carrier family 22, member 20 JBrowse link 1 221,327,608 221,344,367 RGD:6480464
G Slc22a6 solute carrier family 22 member 6 JBrowse link 1 224,824,809 224,833,284 RGD:6480464
G Slc22a8 solute carrier family 22 member 8 JBrowse link 1 224,799,444 224,818,482 RGD:6480464
G Slc27a2 solute carrier family 27 member 2 JBrowse link 3 119,014,620 119,052,531 RGD:6480464
G Slco3a1 solute carrier organic anion transporter family, member 3a1 JBrowse link 1 135,790,854 136,073,640 RGD:6480464
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 10 46,570,996 46,593,021 RGD:6480464
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Trim16 tripartite motif-containing 16 JBrowse link 10 49,231,660 49,254,653 RGD:6480464
G Ttr transthyretin JBrowse link 18 15,532,963 15,542,180 RGD:6480464
G Wnt3 Wnt family member 3 JBrowse link 10 91,830,709 91,874,907 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      biological role 19596
        epitope 6766
          benzylpenicillin 64
            benzylpenamaldate group 0
            benzylpenamidyl group 0
            benzylpenicanyl group 0
            benzylpenicillanyl group 0
            benzylpenicillenyl group 0
            benzylpenicilloyl group + 0
            benzylpenicilloyl polylysine 0
            benzylpenicilloyl-L-lysine + 0
            benzylpenicilloyl-benzylamine 0
            benzylpenicilloyl-butylamine 0
            benzylpenicilloyl-cysteine 0
            benzylpenilloic acid 0
            penamecillin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic group 18331
                              organic divalent group 18321
                                organodiyl group 18321
                                  carbonyl group 18209
                                    carbonyl compound 18209
                                      carboxylic acid 17908
                                        carboacyl group 16930
                                          univalent carboacyl group 16930
                                            carbamoyl group 16610
                                              carboxamide 16610
                                                lactam 2919
                                                  beta-lactam 707
                                                    beta-lactam antibiotic 695
                                                      penams 180
                                                        penicillanic acids 180
                                                          penicillanic acid 180
                                                            6-aminopenicillanic acid 180
                                                              penicillin 180
                                                                penicillin allergen 177
                                                                  benzylpenicillin 64
                                                                    benzylpenamaldate group 0
                                                                    benzylpenamidyl group 0
                                                                    benzylpenicanyl group 0
                                                                    benzylpenicillanyl group 0
                                                                    benzylpenicillenyl group 0
                                                                    benzylpenicilloyl group + 0
                                                                    benzylpenicilloyl polylysine 0
                                                                    benzylpenicilloyl-L-lysine + 0
                                                                    benzylpenicilloyl-benzylamine 0
                                                                    benzylpenicilloyl-butylamine 0
                                                                    benzylpenicilloyl-cysteine 0
                                                                    benzylpenilloic acid 0
                                                                    penamecillin 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.