Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:aureusidin
go back to main search page
Accession:CHEBI:18149 term browser browse the term
Definition:A hydroxyaurone that is aurone substituted by hydroxy groups at positions 4, 6, 3' and 4' respectively.
Synonyms:exact_synonym: (2Z)-2-[(3,4-dihydroxyphenyl)methylidene]-4,6-dihydroxy-1-benzofuran-3(2H)-one
 related_synonym: Formula=C15H10O6;   InChI=1S/C15H10O6/c16-8-5-11(19)14-12(6-8)21-13(15(14)20)4-7-1-2-9(17)10(18)3-7/h1-6,16-19H/b13-4-;   InChIKey=WBEFUVAYFSOUEA-PQMHYQBVSA-N;   SMILES=Oc1cc(O)c2C(=O)\\C(Oc2c1)=C\\c1ccc(O)c(O)c1
 alt_id: CHEBI:13867;   CHEBI:2926
 xref: Beilstein:35491;   CAS:38216-54-5;   KEGG:C08576;   KNApSAcK:C00008027
 xref_mesh: MESH:C416232
 xref: PMID:22924954;   Reaxys:35491
 cyclic_relationship: is_conjugate_acid_of CHEBI:58393


show annotations for term's descendants           Sort by:
 
aureusidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation EXP aureusidin results in increased phosphorylation of AKT1 protein CTD PMID:31790703 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [aureusidin results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [aureusidin results in increased expression of HMOX1 protein]; pyrazolanthrone inhibits the reaction [aureusidin results in increased expression of HMOX1 protein]; SB 203580 inhibits the reaction [aureusidin results in increased expression of HMOX1 protein]
aureusidin results in increased expression of HMOX1 mRNA; aureusidin results in increased expression of HMOX1 protein
CTD PMID:31790703 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Il6 interleukin 6 multiple interactions ISO aureusidin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:31790703 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression EXP aureusidin results in decreased expression of KEAP1 mRNA; aureusidin results in decreased expression of KEAP1 protein CTD PMID:31790703 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
EXP aureusidin results in increased phosphorylation of MAPK1 protein
Acetylcysteine inhibits the reaction [aureusidin results in increased phosphorylation of MAPK1 protein]
CTD PMID:31790703 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
EXP aureusidin results in increased phosphorylation of MAPK3 protein
Acetylcysteine inhibits the reaction [aureusidin results in increased phosphorylation of MAPK3 protein]
CTD PMID:31790703 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
EXP Acetylcysteine inhibits the reaction [aureusidin results in increased phosphorylation of MAPK8 protein] CTD PMID:31790703 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
increases expression
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [aureusidin affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [aureusidin affects the localization of NFE2L2 protein]; aureusidin results in increased expression of and affects the localization of NFE2L2 protein; pyrazolanthrone inhibits the reaction [aureusidin affects the localization of NFE2L2 protein]; SB 203580 inhibits the reaction [aureusidin affects the localization of NFE2L2 protein]
aureusidin results in increased expression of NFE2L2 mRNA
CTD PMID:31790703 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO aureusidin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein] CTD PMID:31790703 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO aureusidin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; aureusidin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:31790703 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP aureusidin results in increased expression of NQO1 mRNA CTD PMID:31790703 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO aureusidin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; aureusidin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:31790703 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO aureusidin inhibits the reaction [Lipopolysaccharides results in increased expression of and affects the localization of RELA protein] CTD PMID:31790703 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO aureusidin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; aureusidin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:31790703 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19720
      biological role 19720
        biochemical role 19310
          metabolite 19292
            eukaryotic metabolite 18963
              plant metabolite 17441
                aureusidin 14
                  4,6,3',4'-tetramethoxyaurone 0
                  aureusidin 6-O-beta-glucoside 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19580
                        carbon atom 19571
                          organic molecular entity 19571
                            organic group 18602
                              organic divalent group 18593
                                organodiyl group 18593
                                  carbonyl group 18506
                                    carbonyl compound 18506
                                      ketone 16825
                                        cyclic ketone 15234
                                          aurone 14
                                            aureusidin 14
                                              4,6,3',4'-tetramethoxyaurone 0
                                              aureusidin 6-O-beta-glucoside 0
paths to the root