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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2-aminophenol
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Accession:CHEBI:18112 term browser browse the term
Definition:The aminophenol which has the single amino substituent located ortho to the phenolic -OH group.
Synonyms:related_synonym: 2-Aminobenzenol;   2-Hydroxyaniline;   Formula=C6H7NO;   InChI=1S/C6H7NO/c7-5-3-1-2-4-6(5)8/h1-4,8H,7H2;   InChIKey=CDAWCLOXVUBKRW-UHFFFAOYSA-N;   SMILES=Nc1ccccc1O;   o-Aminophenol;   o-hydroxyaniline
 alt_id: CHEBI:1023;   CHEBI:11527;   CHEBI:19476;   CHEBI:39779
 xref: CAS:95-55-6;   DrugBank:DB01726;   Gmelin:26978;   Gmelin:606075;   KEGG:C01987;   KNApSAcK:C00007533
 xref_mesh: MESH:C027667
 xref: PDBeChem:2AF;   PMID:11304127;   PMID:1395635;   PMID:24124510;   PMID:24571346;   PMID:9683650;   Reaxys:606075;   UM-BBD_compID:c0316;   Wikipedia:2-Aminophenol


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2-aminophenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO 2-aminophenol results in increased expression of AKR1C2 mRNA CTD PMID:20491607 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO 2-aminophenol results in increased expression of CYP1A1 mRNA CTD PMID:20491607 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO 2-aminophenol results in increased expression of HMOX1 mRNA CTD PMID:20491607 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
affects response to substance
ISO 2-aminophenol results in increased expression of NQO1 mRNA
NQO1 gene SNP affects the susceptibility to 2-aminophenol
CTD PMID:20491607, PMID:25622337 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects response to substance ISO NR3C1 gene SNP affects the susceptibility to 2-aminophenol CTD PMID:25622337 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Rnf115 ring finger protein 115 affects response to substance ISO RNF115 gene SNP affects the susceptibility to 2-aminophenol CTD PMID:25622337 NCBI chr 2:198,852,392...198,920,000
Ensembl chr 2:198,852,500...198,919,995
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        biochemical role 19282
          metabolite 19263
            prokaryotic metabolite 18357
              bacterial metabolite 18357
                2-aminophenol 6
                  2-acetamidophenol sulfate 0
                  2-aminophenyl hydrogen sulfate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    main group molecular entity 19672
                      s-block molecular entity 19430
                        hydrogen molecular entity 19420
                          hydrides 18686
                            inorganic hydride 17411
                              pnictogen hydride 17383
                                nitrogen hydride 17224
                                  azane 16941
                                    ammonia 16940
                                      organic amino compound 16939
                                        aromatic amine 13618
                                          anilines 12329
                                            substituted aniline 11825
                                              aminophenol 10681
                                                2-aminophenol 6
                                                  2-acetamidophenol sulfate 0
                                                  2-aminophenyl hydrogen sulfate 0
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