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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2-aminophenol
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Accession:CHEBI:18112 term browser browse the term
Definition:The aminophenol which has the single amino substituent located ortho to the phenolic -OH group.
Synonyms:related_synonym: 2-Aminobenzenol;   2-Hydroxyaniline;   Formula=C6H7NO;   InChI=1S/C6H7NO/c7-5-3-1-2-4-6(5)8/h1-4,8H,7H2;   InChIKey=CDAWCLOXVUBKRW-UHFFFAOYSA-N;   SMILES=Nc1ccccc1O;   o-Aminophenol;   o-hydroxyaniline
 alt_id: CHEBI:1023;   CHEBI:11527;   CHEBI:19476;   CHEBI:39779
 xref: CAS:95-55-6;   DrugBank:DB01726;   Gmelin:26978;   Gmelin:606075;   KEGG:C01987;   KNApSAcK:C00007533
 xref_mesh: MESH:C027667
 xref: PDBeChem:2AF;   PMID:11304127;   PMID:1395635;   PMID:24124510;   PMID:24571346;   PMID:9683650;   Reaxys:606075;   UM-BBD_compID:c0316;   Wikipedia:2-Aminophenol


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2-aminophenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO 2-aminophenol results in increased expression of AKR1C2 mRNA CTD PMID:20491607 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO 2-aminophenol results in increased expression of CYP1A1 mRNA CTD PMID:20491607 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO 2-aminophenol results in increased expression of HMOX1 mRNA CTD PMID:20491607 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
affects response to substance
ISO 2-aminophenol results in increased expression of NQO1 mRNA
NQO1 gene SNP affects the susceptibility to 2-aminophenol
CTD PMID:20491607 PMID:25622337 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects response to substance ISO NR3C1 gene SNP affects the susceptibility to 2-aminophenol CTD PMID:25622337 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Rnf115 ring finger protein 115 affects response to substance ISO RNF115 gene SNP affects the susceptibility to 2-aminophenol CTD PMID:25622337 NCBI chr 2:184,262,087...184,329,841
Ensembl chr 2:184,262,371...184,329,823
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      biological role 19761
        biochemical role 19381
          metabolite 19356
            prokaryotic metabolite 18420
              bacterial metabolite 18420
                2-aminophenol 6
                  2-acetamidophenol sulfate 0
                  2-aminophenyl hydrogen sulfate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    main group molecular entity 19708
                      s-block molecular entity 19493
                        hydrogen molecular entity 19488
                          hydrides 18845
                            inorganic hydride 17691
                              pnictogen hydride 17672
                                nitrogen hydride 17545
                                  azane 17279
                                    ammonia 17278
                                      organic amino compound 17278
                                        aromatic amine 13701
                                          anilines 12359
                                            substituted aniline 11852
                                              aminophenol 10697
                                                2-aminophenol 6
                                                  2-acetamidophenol sulfate 0
                                                  2-aminophenyl hydrogen sulfate 0
paths to the root