Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1,4-dihydroxy-2-naphthoic acid
go back to main search page
Accession:CHEBI:18094 term browser browse the term
Definition:A naphthoic acid that is 2-naphthoic acid substituted by hydroxy groups at positions 1 and 4.
Synonyms:related_synonym: 1,4-Dihydroxy-2-naphthalenecarboxylic acid;   1,4-dihydroxynaphthalene-2-carboxylic acid;   Formula=C11H8O4;   InChI=1S/C11H8O4/c12-9-5-8(11(14)15)10(13)7-4-2-1-3-6(7)9/h1-5,12-13H,(H,14,15);   InChIKey=VOJUXHHACRXLTD-UHFFFAOYSA-N;   SMILES=OC(=O)c1cc(O)c2ccccc2c1O
 alt_id: CHEBI:18933;   CHEBI:539
 xref: Beilstein:2111226;   CAS:31519-22-9;   ECMDB:ECMDB04054;   KEGG:C03657;   KNApSAcK:C00000736
 xref_mesh: MESH:C024023
 xref: PMID:1091286;   PMID:23801651;   Reaxys:2111226
 cyclic_relationship: is_conjugate_acid_of CHEBI:11173


show annotations for term's descendants           Sort by:
 
1,4-dihydroxy-2-naphthoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO 1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein; [1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; [1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA CTD PMID:27837168 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA CTD PMID:27837168 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA CTD PMID:27837168 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Gpr35 G protein-coupled receptor 35 multiple interactions ISO 1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of GPR35 protein CTD PMID:20826425 NCBI chr 9:100,129,428...100,141,269
Ensembl chr 9:100,137,881...100,138,801
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19761
    role 19711
      biological role 19711
        biochemical role 19301
          metabolite 19282
            xenobiotic metabolite 14244
              2-naphthoic acid 14
                1,4-dihydroxy-2-naphthoic acid 4
                  1,4-dihydroxy-2-naphthoyl-CoA 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19761
    subatomic particle 19759
      composite particle 19759
        hadron 19759
          baryon 19759
            nucleon 19759
              atomic nucleus 19759
                atom 19759
                  main group element atom 19653
                    p-block element atom 19653
                      carbon group element atom 19569
                        carbon atom 19559
                          organic molecular entity 19559
                            organic group 18593
                              organic divalent group 18584
                                organodiyl group 18584
                                  carbonyl group 18499
                                    carbonyl compound 18499
                                      carboxylic acid 18151
                                        hydroxy carboxylic acid 3616
                                          hydroxy monocarboxylic acid 3616
                                            dihydroxy monocarboxylic acid 256
                                              1,4-dihydroxy-2-naphthoic acid 4
                                                1,4-dihydroxy-2-naphthoyl-CoA 0
paths to the root